ISMARA results: WT1_MTF1

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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for WT1_MTF1_ZBTB7B

Z-value: 4.15

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Transcription factors associated with WT1_MTF1_ZBTB7B

Gene Symbol	Gene ID	Gene Info
WT1 Ensembl NCBI GeneCards UniProt	ENSG00000184937.8	WT1 transcription factor
MTF1 Ensembl NCBI GeneCards UniProt	ENSG00000188786.9	metal regulatory transcription factor 1
ZBTB7B Ensembl NCBI GeneCards UniProt	ENSG00000160685.9	zinc finger and BTB domain containing 7B

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZBTB7B	hg19_v2_chr1_+_154975258_154975330	0.73	7.0e-37	Click!
WT1	hg19_v2_chr11_-_32457075_32457095	0.36	4.1e-08	Click!
MTF1	hg19_v2_chr1_-_38325256_38325292	-0.19	5.7e-03	Click!

Activity profile of WT1_MTF1_ZBTB7B motif

Sorted Z-values of WT1_MTF1_ZBTB7B motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_-_2906979 Show fit	173.24	ENST00000380725.1 ENST00000313407.6 ENST00000430149.2 ENST00000440480.2 ENST00000414822.3	CDKN1C Ensembl NCBI GeneCards UniProt Show fit	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr1_+_6845384 Show fit	159.83	ENST00000303635.7	CAMTA1 Ensembl NCBI GeneCards UniProt Show fit	calmodulin binding transcription activator 1
chr16_+_58497567 Show fit	130.00	ENST00000258187.5	NDRG4 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 4
chr1_-_20812690 Show fit	128.16	ENST00000375078.3	CAMK2N1 Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr14_+_102027688 Show fit	127.92	ENST00000510508.4 ENST00000359323.3	DIO3 Ensembl NCBI GeneCards UniProt Show fit	deiodinase, iodothyronine, type III
chr16_+_226658 Show fit	127.65	ENST00000320868.5 ENST00000397797.1	HBA1 Ensembl NCBI GeneCards UniProt Show fit	hemoglobin, alpha 1
chr12_-_124457257 Show fit	126.33	ENST00000545891.1	CCDC92 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 92
chr11_-_12030629 Show fit	125.62	ENST00000396505.2	DKK3 Ensembl NCBI GeneCards UniProt Show fit	dickkopf WNT signaling pathway inhibitor 3
chr14_-_81687197 Show fit	124.37	ENST00000553612.1	GTF2A1 Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIA, 1, 19/37kDa
chr9_+_139873264 Show fit	122.47	ENST00000446677.1	PTGDS Ensembl NCBI GeneCards UniProt Show fit	prostaglandin D2 synthase 21kDa (brain)
chr17_+_77751931 Show fit	121.15	ENST00000310942.4 ENST00000269399.5	CBX2 Ensembl NCBI GeneCards UniProt Show fit	chromobox homolog 2
chr10_+_124221036 Show fit	117.40	ENST00000368984.3	HTRA1 Ensembl NCBI GeneCards UniProt Show fit	HtrA serine peptidase 1
chr16_+_222846 Show fit	111.81	ENST00000251595.6 ENST00000397806.1	HBA2 Ensembl NCBI GeneCards UniProt Show fit	hemoglobin, alpha 2
chr9_+_137979506 Show fit	105.66	ENST00000539529.1 ENST00000392991.4 ENST00000371793.3	OLFM1 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin 1
chr12_-_124457371 Show fit	102.92	ENST00000238156.3 ENST00000545037.1	CCDC92 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 92
chr20_-_35492048 Show fit	101.33	ENST00000237536.4	SOGA1 Ensembl NCBI GeneCards UniProt Show fit	suppressor of glucose, autophagy associated 1
chr15_+_80696666 Show fit	100.43	ENST00000303329.4	ARNT2 Ensembl NCBI GeneCards UniProt Show fit	aryl-hydrocarbon receptor nuclear translocator 2
chr19_+_708910 Show fit	100.17	ENST00000264560.7	PALM Ensembl NCBI GeneCards UniProt Show fit	paralemmin
chr20_-_3154162 Show fit	94.94	ENST00000360342.3	LZTS3 Ensembl NCBI GeneCards UniProt Show fit	Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr7_-_44365020 Show fit	94.63	ENST00000395747.2 ENST00000347193.4 ENST00000346990.4 ENST00000258682.6 ENST00000353625.4 ENST00000421607.1 ENST00000424197.1 ENST00000502837.2 ENST00000350811.3 ENST00000395749.2	CAMK2B Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin-dependent protein kinase II beta
chr19_+_709101 Show fit	90.41	ENST00000338448.5	PALM Ensembl NCBI GeneCards UniProt Show fit	paralemmin
chr9_+_130374537 Show fit	89.20	ENST00000373302.3 ENST00000373299.1	STXBP1 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 1
chr10_-_79397391 Show fit	88.76	ENST00000286628.8 ENST00000406533.3 ENST00000354353.5 ENST00000404857.1	KCNMA1 Ensembl NCBI GeneCards UniProt Show fit	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr8_+_144816303 Show fit	85.84	ENST00000533004.1	FAM83H-AS1 Ensembl NCBI GeneCards UniProt Show fit	FAM83H antisense RNA 1 (head to head)
chr4_-_5894777 Show fit	81.15	ENST00000324989.7	CRMP1 Ensembl NCBI GeneCards UniProt Show fit	collapsin response mediator protein 1
chr19_+_35521616 Show fit	81.01	ENST00000595652.1	SCN1B Ensembl NCBI GeneCards UniProt Show fit	sodium channel, voltage-gated, type I, beta subunit
chr6_-_46459099 Show fit	78.68	ENST00000371374.1	RCAN2 Ensembl NCBI GeneCards UniProt Show fit	regulator of calcineurin 2
chr11_-_134281812 Show fit	78.58	ENST00000392580.1 ENST00000312527.4	B3GAT1 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr11_-_12030905 Show fit	78.20	ENST00000326932.4	DKK3 Ensembl NCBI GeneCards UniProt Show fit	dickkopf WNT signaling pathway inhibitor 3
chr16_+_56623433 Show fit	76.07	ENST00000570176.1	MT3 Ensembl NCBI GeneCards UniProt Show fit	metallothionein 3
chr16_+_1203194 Show fit	74.07	ENST00000348261.5 ENST00000358590.4	CACNA1H Ensembl NCBI GeneCards UniProt Show fit	calcium channel, voltage-dependent, T type, alpha 1H subunit
chrX_-_2418596 Show fit	73.92	ENST00000381218.3	ZBED1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, BED-type containing 1
chr1_+_169075554 Show fit	69.50	ENST00000367815.4	ATP1B1 Ensembl NCBI GeneCards UniProt Show fit	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_-_44365216 Show fit	69.34	ENST00000358707.3 ENST00000457475.1 ENST00000440254.2	CAMK2B Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin-dependent protein kinase II beta
chrX_+_153237740 Show fit	69.28	ENST00000369982.4	TMEM187 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 187
chr13_-_110438914 Show fit	69.24	ENST00000375856.3	IRS2 Ensembl NCBI GeneCards UniProt Show fit	insulin receptor substrate 2
chr14_-_100070363 Show fit	69.07	ENST00000380243.4	CCDC85C Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 85C
chr10_-_75634219 Show fit	67.89	ENST00000305762.7	CAMK2G Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin-dependent protein kinase II gamma
chr16_+_69166418 Show fit	67.79	ENST00000314423.7 ENST00000562237.1 ENST00000567460.1 ENST00000566227.1 ENST00000352319.4 ENST00000563094.1	CIRH1A Ensembl NCBI GeneCards UniProt Show fit	cirrhosis, autosomal recessive 1A (cirhin)
chr20_+_34742650 Show fit	67.74	ENST00000373945.1 ENST00000338074.2	EPB41L1 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1-like 1
chr14_-_81687575 Show fit	67.51	ENST00000434192.2	GTF2A1 Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIA, 1, 19/37kDa
chr20_+_10199468 Show fit	67.15	ENST00000254976.2 ENST00000304886.2	SNAP25 Ensembl NCBI GeneCards UniProt Show fit	synaptosomal-associated protein, 25kDa
chr19_-_49944806 Show fit	67.13	ENST00000221485.3	SLC17A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 (vesicular glutamate transporter), member 7
chr19_+_589893 Show fit	66.60	ENST00000251287.2	HCN2 Ensembl NCBI GeneCards UniProt Show fit	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr22_+_45898712 Show fit	66.41	ENST00000455233.1 ENST00000348697.2 ENST00000402984.3 ENST00000262722.7 ENST00000327858.6 ENST00000442170.2 ENST00000340923.5 ENST00000439835.1	FBLN1 Ensembl NCBI GeneCards UniProt Show fit	fibulin 1
chr3_-_149688655 Show fit	66.05	ENST00000461930.1 ENST00000423691.2 ENST00000490975.1 ENST00000461868.1 ENST00000452853.2	PFN2 Ensembl NCBI GeneCards UniProt Show fit	profilin 2
chr19_+_45409011 Show fit	66.04	ENST00000252486.4 ENST00000446996.1 ENST00000434152.1	APOE Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein E
chr4_+_4388805 Show fit	65.63	ENST00000504171.1	NSG1 Ensembl NCBI GeneCards UniProt Show fit	Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr4_-_84406218 Show fit	65.60	ENST00000515303.1	FAM175A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 175, member A
chr1_-_11714700 Show fit	65.29	ENST00000354287.4	FBXO2 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 2
chr3_-_149688502 Show fit	65.21	ENST00000481767.1 ENST00000475518.1	PFN2 Ensembl NCBI GeneCards UniProt Show fit	profilin 2
chr20_-_62130474 Show fit	64.89	ENST00000217182.3	EEF1A2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 alpha 2
chr3_+_14989186 Show fit	64.48	ENST00000435454.1 ENST00000323373.6	NR2C2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2, group C, member 2
chr12_+_110718921 Show fit	64.06	ENST00000308664.6	ATP2A2 Ensembl NCBI GeneCards UniProt Show fit	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr17_-_15903002 Show fit	63.97	ENST00000399277.1	ZSWIM7 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, SWIM-type containing 7
chr19_+_35521572 Show fit	63.59	ENST00000262631.5	SCN1B Ensembl NCBI GeneCards UniProt Show fit	sodium channel, voltage-gated, type I, beta subunit
chr8_+_1922024 Show fit	62.54	ENST00000320248.3	KBTBD11 Ensembl NCBI GeneCards UniProt Show fit	kelch repeat and BTB (POZ) domain containing 11
chr11_-_64410787 Show fit	62.47	ENST00000301894.2	NRXN2 Ensembl NCBI GeneCards UniProt Show fit	neurexin 2
chr8_+_1711918 Show fit	62.31	ENST00000331222.4	CLN8 Ensembl NCBI GeneCards UniProt Show fit	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr14_+_29236269 Show fit	61.84	ENST00000313071.4	FOXG1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box G1
chr7_-_105029812 Show fit	61.65	ENST00000482897.1	SRPK2 Ensembl NCBI GeneCards UniProt Show fit	SRSF protein kinase 2
chr19_-_36523709 Show fit	61.31	ENST00000592017.1 ENST00000360535.4	CLIP3 Ensembl NCBI GeneCards UniProt Show fit	CAP-GLY domain containing linker protein 3
chrX_+_38420783 Show fit	61.25	ENST00000422612.2 ENST00000286824.6 ENST00000545599.1	TSPAN7 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 7
chr16_+_56659687 Show fit	61.02	ENST00000568293.1 ENST00000330439.6	MT1E Ensembl NCBI GeneCards UniProt Show fit	metallothionein 1E
chr15_+_68871308 Show fit	60.88	ENST00000261861.5	CORO2B Ensembl NCBI GeneCards UniProt Show fit	coronin, actin binding protein, 2B
chr16_-_1020849 Show fit	60.87	ENST00000568897.1	LMF1 Ensembl NCBI GeneCards UniProt Show fit	lipase maturation factor 1
chr3_-_132441209 Show fit	60.61	ENST00000383282.2 ENST00000326682.8 ENST00000343113.4 ENST00000337331.5	NPHP3 Ensembl NCBI GeneCards UniProt Show fit	nephronophthisis 3 (adolescent)
chrX_-_13956497 Show fit	59.66	ENST00000398361.3	GPM6B Ensembl NCBI GeneCards UniProt Show fit	glycoprotein M6B
chr14_+_96505659 Show fit	59.63	ENST00000555004.1	C14orf132 Ensembl NCBI GeneCards UniProt Show fit	chromosome 14 open reading frame 132
chr11_-_116968987 Show fit	59.63	ENST00000434315.2 ENST00000292055.4 ENST00000375288.1 ENST00000542607.1 ENST00000445177.1 ENST00000375300.1 ENST00000446921.2	SIK3 Ensembl NCBI GeneCards UniProt Show fit	SIK family kinase 3
chr16_+_58533951 Show fit	59.58	ENST00000566192.1 ENST00000565088.1 ENST00000568640.1 ENST00000563978.1 ENST00000569923.1 ENST00000356752.4 ENST00000563799.1 ENST00000562999.1 ENST00000570248.1 ENST00000562731.1 ENST00000568424.1	NDRG4 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 4
chr11_-_64512273 Show fit	59.32	ENST00000377497.3 ENST00000377487.1 ENST00000430645.1	RASGRP2 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr4_-_8873531 Show fit	59.22	ENST00000400677.3	HMX1 Ensembl NCBI GeneCards UniProt Show fit	H6 family homeobox 1
chrX_+_135229600 Show fit	58.96	ENST00000370690.3	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr11_-_117747607 Show fit	58.42	ENST00000540359.1 ENST00000539526.1	FXYD6 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 6
chr16_+_56642489 Show fit	58.36	ENST00000561491.1	MT2A Ensembl NCBI GeneCards UniProt Show fit	metallothionein 2A
chr22_-_38851205 Show fit	58.34	ENST00000303592.3	KCNJ4 Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly-rectifying channel, subfamily J, member 4
chr9_+_140513438 Show fit	58.26	ENST00000462484.1 ENST00000334856.6 ENST00000460843.1	EHMT1 Ensembl NCBI GeneCards UniProt Show fit	euchromatic histone-lysine N-methyltransferase 1
chrX_+_135229559 Show fit	58.18	ENST00000394155.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chrX_+_11776410 Show fit	57.81	ENST00000361672.2	MSL3 Ensembl NCBI GeneCards UniProt Show fit	male-specific lethal 3 homolog (Drosophila)
chr2_+_242641442 Show fit	57.27	ENST00000313552.6 ENST00000406941.1	ING5 Ensembl NCBI GeneCards UniProt Show fit	inhibitor of growth family, member 5
chr6_-_29600832 Show fit	57.17	ENST00000377016.4 ENST00000376977.3 ENST00000377034.4	GABBR1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid (GABA) B receptor, 1
chr12_+_53773944 Show fit	57.09	ENST00000551969.1 ENST00000327443.4	SP1 Ensembl NCBI GeneCards UniProt Show fit	Sp1 transcription factor
chr16_+_640201 Show fit	56.62	ENST00000563109.1	RAB40C Ensembl NCBI GeneCards UniProt Show fit	RAB40C, member RAS oncogene family
chr17_+_4710391 Show fit	56.58	ENST00000263088.6 ENST00000572940.1	PLD2 Ensembl NCBI GeneCards UniProt Show fit	phospholipase D2
chr2_+_46524537 Show fit	56.54	ENST00000263734.3	EPAS1 Ensembl NCBI GeneCards UniProt Show fit	endothelial PAS domain protein 1
chr9_-_98079965 Show fit	56.28	ENST00000289081.3	FANCC Ensembl NCBI GeneCards UniProt Show fit	Fanconi anemia, complementation group C
chr12_-_54982300 Show fit	56.28	ENST00000547431.1	PPP1R1A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr1_+_25944341 Show fit	56.24	ENST00000263979.3	MAN1C1 Ensembl NCBI GeneCards UniProt Show fit	mannosidase, alpha, class 1C, member 1
chr12_+_10365404 Show fit	56.19	ENST00000266458.5 ENST00000421801.2 ENST00000544284.1 ENST00000545047.1 ENST00000543602.1 ENST00000545887.1	GABARAPL1 Ensembl NCBI GeneCards UniProt Show fit	GABA(A) receptor-associated protein like 1
chr2_+_10183651 Show fit	56.18	ENST00000305883.1	KLF11 Ensembl NCBI GeneCards UniProt Show fit	Kruppel-like factor 11
chr10_+_180987 Show fit	56.00	ENST00000381591.1	ZMYND11 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, MYND-type containing 11
chr19_+_33685490 Show fit	55.87	ENST00000253193.7	LRP3 Ensembl NCBI GeneCards UniProt Show fit	low density lipoprotein receptor-related protein 3
chr15_-_77712477 Show fit	55.85	ENST00000560626.2	PEAK1 Ensembl NCBI GeneCards UniProt Show fit	pseudopodium-enriched atypical kinase 1
chr16_+_84002234 Show fit	55.82	ENST00000305202.4	NECAB2 Ensembl NCBI GeneCards UniProt Show fit	N-terminal EF-hand calcium binding protein 2
chr14_-_21493649 Show fit	55.82	ENST00000553442.1 ENST00000555869.1 ENST00000556457.1 ENST00000397844.2 ENST00000554415.1	NDRG2 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 2
chr22_-_39548627 Show fit	55.81	ENST00000216133.5	CBX7 Ensembl NCBI GeneCards UniProt Show fit	chromobox homolog 7
chrX_+_38420623 Show fit	55.67	ENST00000378482.2	TSPAN7 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 7
chr1_+_151254738 Show fit	55.36	ENST00000336715.6 ENST00000324048.5 ENST00000368879.2	ZNF687 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 687
chr7_-_158380371 Show fit	55.34	ENST00000389418.4 ENST00000389416.4	PTPRN2 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr10_-_735553 Show fit	55.28	ENST00000280886.6 ENST00000423550.1	DIP2C Ensembl NCBI GeneCards UniProt Show fit	DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr19_-_16582815 Show fit	55.09	ENST00000455140.2 ENST00000248070.6 ENST00000594975.1	EPS15L1 Ensembl NCBI GeneCards UniProt Show fit	epidermal growth factor receptor pathway substrate 15-like 1
chr2_+_26915584 Show fit	54.88	ENST00000302909.3	KCNK3 Ensembl NCBI GeneCards UniProt Show fit	potassium channel, subfamily K, member 3
chr10_-_105452917 Show fit	54.85	ENST00000427662.2	SH3PXD2A Ensembl NCBI GeneCards UniProt Show fit	SH3 and PX domains 2A
chr11_+_125774362 Show fit	54.52	ENST00000530414.1 ENST00000530129.2	DDX25 Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr2_+_20646824 Show fit	54.37	ENST00000272233.4	RHOB Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member B
chr7_+_65338230 Show fit	54.33	ENST00000360768.3	VKORC1L1 Ensembl NCBI GeneCards UniProt Show fit	vitamin K epoxide reductase complex, subunit 1-like 1
chr19_-_460996 Show fit	54.19	ENST00000264554.6	SHC2 Ensembl NCBI GeneCards UniProt Show fit	SHC (Src homology 2 domain containing) transforming protein 2
chr5_-_11904152 Show fit	54.13	ENST00000304623.8 ENST00000458100.2	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin (cadherin-associated protein), delta 2
chr12_+_57610562 Show fit	54.10	ENST00000349394.5	NXPH4 Ensembl NCBI GeneCards UniProt Show fit	neurexophilin 4
chr16_+_85061367 Show fit	53.93	ENST00000538274.1 ENST00000258180.3	KIAA0513 Ensembl NCBI GeneCards UniProt Show fit	KIAA0513
chr1_-_182360918 Show fit	53.85	ENST00000339526.4	GLUL Ensembl NCBI GeneCards UniProt Show fit	glutamate-ammonia ligase
chr8_-_11725549 Show fit	53.75	ENST00000505496.2 ENST00000534636.1 ENST00000524500.1 ENST00000345125.3 ENST00000453527.2 ENST00000527215.2 ENST00000532392.1 ENST00000533455.1 ENST00000534510.1 ENST00000530640.2 ENST00000531089.1 ENST00000532656.2 ENST00000531502.1 ENST00000434271.1 ENST00000353047.6	CTSB Ensembl NCBI GeneCards UniProt Show fit	cathepsin B
chr3_+_50712672 Show fit	53.72	ENST00000266037.9	DOCK3 Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 3
chr13_-_30881621 Show fit	53.52	ENST00000380615.3	KATNAL1 Ensembl NCBI GeneCards UniProt Show fit	katanin p60 subunit A-like 1
chr5_+_76506706 Show fit	53.51	ENST00000340978.3 ENST00000346042.3 ENST00000264917.5 ENST00000342343.4 ENST00000333194.4	PDE8B Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 8B
chr14_+_100150622 Show fit	53.49	ENST00000261835.3	CYP46A1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450, family 46, subfamily A, polypeptide 1
chr9_+_17579084 Show fit	53.48	ENST00000380607.4	SH3GL2 Ensembl NCBI GeneCards UniProt Show fit	SH3-domain GRB2-like 2
chr4_-_5890145 Show fit	53.44	ENST00000397890.2	CRMP1 Ensembl NCBI GeneCards UniProt Show fit	collapsin response mediator protein 1
chr1_-_235813290 Show fit	53.09	ENST00000391854.2	GNG4 Ensembl NCBI GeneCards UniProt Show fit	guanine nucleotide binding protein (G protein), gamma 4
chr14_+_105781048 Show fit	53.05	ENST00000458164.2 ENST00000447393.1	PACS2 Ensembl NCBI GeneCards UniProt Show fit	phosphofurin acidic cluster sorting protein 2
chr11_-_111783595 Show fit	53.01	ENST00000528628.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr1_-_32229523 Show fit	53.00	ENST00000398547.1 ENST00000373655.2 ENST00000373658.3 ENST00000257070.4	BAI2 Ensembl NCBI GeneCards UniProt Show fit	brain-specific angiogenesis inhibitor 2
chr9_-_138799070 Show fit	52.91	ENST00000389532.4 ENST00000409386.3	CAMSAP1 Ensembl NCBI GeneCards UniProt Show fit	calmodulin regulated spectrin-associated protein 1
chr11_-_777467 Show fit	52.73	ENST00000397472.2 ENST00000524550.1 ENST00000319863.8 ENST00000526325.1 ENST00000442059.2	PDDC1 Ensembl NCBI GeneCards UniProt Show fit	Parkinson disease 7 domain containing 1
chr22_+_43808014 Show fit	52.67	ENST00000334209.5 ENST00000443721.1 ENST00000414469.2 ENST00000439548.1	MPPED1 Ensembl NCBI GeneCards UniProt Show fit	metallophosphoesterase domain containing 1
chr6_-_84418860 Show fit	52.44	ENST00000521743.1	SNAP91 Ensembl NCBI GeneCards UniProt Show fit	synaptosomal-associated protein, 91kDa
chr2_+_54198210 Show fit	52.43	ENST00000607452.1 ENST00000422521.2	ACYP2 Ensembl NCBI GeneCards UniProt Show fit	acylphosphatase 2, muscle type
chr16_+_1662326 Show fit	52.42	ENST00000397412.3	CRAMP1L Ensembl NCBI GeneCards UniProt Show fit	Crm, cramped-like (Drosophila)
chr9_+_130965677 Show fit	52.11	ENST00000393594.3 ENST00000486160.1	DNM1 Ensembl NCBI GeneCards UniProt Show fit	dynamin 1
chr22_+_17082732 Show fit	51.84	ENST00000558085.2 ENST00000592918.1 ENST00000400593.2 ENST00000592107.1 ENST00000426585.1 ENST00000591299.1	TPTEP1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane phosphatase with tensin homology pseudogene 1
chr6_+_31865552 Show fit	51.82	ENST00000469372.1 ENST00000497706.1	C2 Ensembl NCBI GeneCards UniProt Show fit	complement component 2
chr8_-_18871159 Show fit	51.79	ENST00000327040.8 ENST00000440756.2	PSD3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing 3
chr13_+_27131798 Show fit	51.77	ENST00000361042.4	WASF3 Ensembl NCBI GeneCards UniProt Show fit	WAS protein family, member 3
chr15_-_83316254 Show fit	51.74	ENST00000567678.1 ENST00000450751.2	CPEB1 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic polyadenylation element binding protein 1
chr3_-_126194707 Show fit	51.73	ENST00000336332.5 ENST00000389709.3	ZXDC Ensembl NCBI GeneCards UniProt Show fit	ZXD family zinc finger C
chr14_-_103987679 Show fit	51.69	ENST00000553610.1	CKB Ensembl NCBI GeneCards UniProt Show fit	creatine kinase, brain
chr10_-_75634260 Show fit	51.34	ENST00000372765.1 ENST00000351293.3	CAMK2G Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin-dependent protein kinase II gamma
chr5_-_693500 Show fit	51.32	ENST00000360578.5	TPPP Ensembl NCBI GeneCards UniProt Show fit	tubulin polymerization promoting protein
chr17_-_74707037 Show fit	51.30	ENST00000355797.3 ENST00000375036.2 ENST00000449428.2	MXRA7 Ensembl NCBI GeneCards UniProt Show fit	matrix-remodelling associated 7
chr4_+_1795012 Show fit	51.22	ENST00000481110.2 ENST00000340107.4 ENST00000440486.2 ENST00000412135.2	FGFR3 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor receptor 3
chr20_-_23618582 Show fit	50.65	ENST00000398411.1 ENST00000376925.3	CST3 Ensembl NCBI GeneCards UniProt Show fit	cystatin C
chr1_-_32229934 Show fit	50.48	ENST00000398542.1	BAI2 Ensembl NCBI GeneCards UniProt Show fit	brain-specific angiogenesis inhibitor 2
chr12_-_54982420 Show fit	50.41	ENST00000257905.8	PPP1R1A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr9_+_132427883 Show fit	50.37	ENST00000372469.4	PRRX2 Ensembl NCBI GeneCards UniProt Show fit	paired related homeobox 2
chr5_-_11904100 Show fit	50.34	ENST00000359640.2	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin (cadherin-associated protein), delta 2
chr22_+_19701985 Show fit	50.21	ENST00000455784.2 ENST00000406395.1	SEPT5 Ensembl NCBI GeneCards UniProt Show fit	septin 5
chr8_+_142402089 Show fit	50.12	ENST00000521578.1 ENST00000520105.1 ENST00000523147.1	PTP4A3 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase type IVA, member 3
chr6_-_84419101 Show fit	50.06	ENST00000520302.1 ENST00000520213.1 ENST00000439399.2 ENST00000428679.2 ENST00000437520.1	SNAP91 Ensembl NCBI GeneCards UniProt Show fit	synaptosomal-associated protein, 91kDa
chr2_-_38604398 Show fit	50.01	ENST00000443098.1 ENST00000449130.1 ENST00000378954.4 ENST00000539122.1 ENST00000419554.2 ENST00000451483.1 ENST00000406122.1	ATL2 Ensembl NCBI GeneCards UniProt Show fit	atlastin GTPase 2
chr15_+_68871569 Show fit	49.83	ENST00000566799.1	CORO2B Ensembl NCBI GeneCards UniProt Show fit	coronin, actin binding protein, 2B
chr15_-_44829057 Show fit	49.62	ENST00000559356.1 ENST00000560049.1 ENST00000313807.4	EIF3J-AS1 Ensembl NCBI GeneCards UniProt Show fit	EIF3J antisense RNA 1 (head to head)
chr1_+_1981890 Show fit	49.50	ENST00000378567.3 ENST00000468310.1	PRKCZ Ensembl NCBI GeneCards UniProt Show fit	protein kinase C, zeta
chr8_+_136469684 Show fit	49.41	ENST00000355849.5	KHDRBS3 Ensembl NCBI GeneCards UniProt Show fit	KH domain containing, RNA binding, signal transduction associated 3
chr7_-_139477500 Show fit	49.16	ENST00000406875.3 ENST00000428878.2	HIPK2 Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 2
chr22_+_51039098 Show fit	49.07	ENST00000399912.1 ENST00000329492.3 ENST00000442429.2 ENST00000341339.4	MAPK8IP2 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 8 interacting protein 2
chr5_+_17217669 Show fit	49.04	ENST00000322611.3	BASP1 Ensembl NCBI GeneCards UniProt Show fit	brain abundant, membrane attached signal protein 1
chr15_+_99791567 Show fit	48.95	ENST00000558879.1 ENST00000301981.3 ENST00000422500.2 ENST00000447360.2 ENST00000442993.2	LRRC28 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 28
chr3_-_194991876 Show fit	48.92	ENST00000310380.6	XXYLT1 Ensembl NCBI GeneCards UniProt Show fit	xyloside xylosyltransferase 1
chr22_+_41777927 Show fit	48.88	ENST00000266304.4	TEF Ensembl NCBI GeneCards UniProt Show fit	thyrotrophic embryonic factor
chr18_-_78005231 Show fit	48.84	ENST00000470488.2 ENST00000353265.3	PARD6G Ensembl NCBI GeneCards UniProt Show fit	par-6 family cell polarity regulator gamma
chr2_-_25896380 Show fit	48.83	ENST00000545439.1 ENST00000407186.1 ENST00000406818.3 ENST00000404103.3 ENST00000407661.3 ENST00000407038.3 ENST00000405222.1 ENST00000288642.8	DTNB Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin, beta
chr7_-_158622210 Show fit	48.74	ENST00000251527.5	ESYT2 Ensembl NCBI GeneCards UniProt Show fit	extended synaptotagmin-like protein 2
chr2_+_17935119 Show fit	48.62	ENST00000317402.7	GEN1 Ensembl NCBI GeneCards UniProt Show fit	GEN1 Holliday junction 5' flap endonuclease
chr11_-_113746212 Show fit	48.56	ENST00000537642.1 ENST00000537706.1 ENST00000544750.1 ENST00000260188.5 ENST00000540925.1	USP28 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 28
chr13_+_27131887 Show fit	48.50	ENST00000335327.5	WASF3 Ensembl NCBI GeneCards UniProt Show fit	WAS protein family, member 3
chr7_+_94023873 Show fit	48.38	ENST00000297268.6	COL1A2 Ensembl NCBI GeneCards UniProt Show fit	collagen, type I, alpha 2
chr19_-_18717627 Show fit	48.37	ENST00000392386.3	CRLF1 Ensembl NCBI GeneCards UniProt Show fit	cytokine receptor-like factor 1
chr15_+_74833518 Show fit	48.27	ENST00000346246.5	ARID3B Ensembl NCBI GeneCards UniProt Show fit	AT rich interactive domain 3B (BRIGHT-like)
chr15_+_69222827 Show fit	48.25	ENST00000310673.3 ENST00000448182.3 ENST00000260364.5	SPESP1 Ensembl NCBI GeneCards UniProt Show fit NOX5 Ensembl NCBI GeneCards UniProt Show fit	sperm equatorial segment protein 1 NADPH oxidase, EF-hand calcium binding domain 5
chr1_+_156698708 Show fit	48.14	ENST00000519086.1	RRNAD1 Ensembl NCBI GeneCards UniProt Show fit	ribosomal RNA adenine dimethylase domain containing 1
chr3_-_183543301 Show fit	48.05	ENST00000318631.3 ENST00000431348.1	MAP6D1 Ensembl NCBI GeneCards UniProt Show fit	MAP6 domain containing 1
chr11_-_2160611 Show fit	48.00	ENST00000416167.2	IGF2 Ensembl NCBI GeneCards UniProt Show fit	insulin-like growth factor 2 (somatomedin A)
chr9_+_132934835 Show fit	47.99	ENST00000372398.3	NCS1 Ensembl NCBI GeneCards UniProt Show fit	neuronal calcium sensor 1
chr1_-_182361327 Show fit	47.98	ENST00000331872.6 ENST00000311223.5	GLUL Ensembl NCBI GeneCards UniProt Show fit	glutamate-ammonia ligase
chrX_-_13956737 Show fit	47.85	ENST00000454189.2	GPM6B Ensembl NCBI GeneCards UniProt Show fit	glycoprotein M6B
chrX_-_17878827 Show fit	47.84	ENST00000360011.1	RAI2 Ensembl NCBI GeneCards UniProt Show fit	retinoic acid induced 2
chr1_-_182360498 Show fit	47.80	ENST00000417584.2	GLUL Ensembl NCBI GeneCards UniProt Show fit	glutamate-ammonia ligase
chr16_-_402639 Show fit	47.79	ENST00000262320.3	AXIN1 Ensembl NCBI GeneCards UniProt Show fit	axin 1
chr9_-_99417562 Show fit	47.71	ENST00000375234.3 ENST00000446045.1	AAED1 Ensembl NCBI GeneCards UniProt Show fit	AhpC/TSA antioxidant enzyme domain containing 1
chr11_-_64511789 Show fit	47.60	ENST00000419843.1 ENST00000394430.1	RASGRP2 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chrX_+_135229731 Show fit	47.60	ENST00000420362.1	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr19_+_50706866 Show fit	47.52	ENST00000440075.2 ENST00000376970.2 ENST00000425460.1 ENST00000599920.1 ENST00000601313.1	MYH14 Ensembl NCBI GeneCards UniProt Show fit	myosin, heavy chain 14, non-muscle
chr3_+_49507674 Show fit	47.51	ENST00000431960.1 ENST00000452317.1 ENST00000435508.2 ENST00000452060.1 ENST00000428779.1 ENST00000419218.1 ENST00000430636.1	DAG1 Ensembl NCBI GeneCards UniProt Show fit	dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr7_-_143059780 Show fit	47.48	ENST00000409578.1 ENST00000409346.1	FAM131B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 131, member B
chr9_-_13279589 Show fit	47.40	ENST00000319217.7	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain protein
chr1_+_10270863 Show fit	47.22	ENST00000377093.4 ENST00000263934.6	KIF1B Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 1B
chr2_+_17935383 Show fit	47.14	ENST00000524465.1 ENST00000381254.2 ENST00000532257.1	GEN1 Ensembl NCBI GeneCards UniProt Show fit	GEN1 Holliday junction 5' flap endonuclease
chr20_-_50385138 Show fit	47.13	ENST00000338821.5	ATP9A Ensembl NCBI GeneCards UniProt Show fit	ATPase, class II, type 9A
chr7_-_105029329 Show fit	46.78	ENST00000393651.3 ENST00000460391.1	SRPK2 Ensembl NCBI GeneCards UniProt Show fit	SRSF protein kinase 2
chr7_+_45613958 Show fit	46.78	ENST00000297323.7	ADCY1 Ensembl NCBI GeneCards UniProt Show fit	adenylate cyclase 1 (brain)
chr9_-_13279563 Show fit	46.67	ENST00000541718.1	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain protein
chr22_-_45559642 Show fit	46.63	ENST00000426282.2	CTA-217C2.1 Ensembl NCBI GeneCards UniProt Show fit	CTA-217C2.1
chr17_-_79139817 Show fit	46.51	ENST00000326724.4	AATK Ensembl NCBI GeneCards UniProt Show fit	apoptosis-associated tyrosine kinase
chr11_-_113746277 Show fit	46.40	ENST00000003302.4 ENST00000545540.1	USP28 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 28
chr19_-_4457776 Show fit	46.31	ENST00000301281.6	UBXN6 Ensembl NCBI GeneCards UniProt Show fit	UBX domain protein 6
chr9_-_13279406 Show fit	46.18	ENST00000546205.1	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain protein
chr2_-_175869936 Show fit	46.11	ENST00000409900.3	CHN1 Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr11_-_236326 Show fit	45.92	ENST00000525237.1 ENST00000532956.1 ENST00000525319.1 ENST00000524564.1 ENST00000382743.4	SIRT3 Ensembl NCBI GeneCards UniProt Show fit	sirtuin 3
chr16_+_56225248 Show fit	45.88	ENST00000262493.6	GNAO1 Ensembl NCBI GeneCards UniProt Show fit	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

Network of associatons between targets according to the STRING database.

First level regulatory network of WT1_MTF1_ZBTB7B

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
51.0	203.8	GO:1902612	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
50.9	152.8	GO:0021966	corticospinal neuron axon guidance(GO:0021966)
46.4	139.1	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
44.9	134.6	GO:1904617	negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
44.5	133.4	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
38.9	116.7	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
38.8	116.4	GO:0071140	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
37.4	149.6	GO:0006542	glutamine biosynthetic process(GO:0006542)
30.3	90.8	GO:0043012	regulation of fusion of sperm to egg plasma membrane(GO:0043012)
29.3	263.6	GO:0003190	atrioventricular valve formation(GO:0003190)
28.3	226.5	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
28.0	84.1	GO:0042137	sequestering of neurotransmitter(GO:0042137)
27.1	135.3	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
26.6	53.1	GO:0042308	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
26.5	79.5	GO:0014807	regulation of somitogenesis(GO:0014807)
26.1	104.3	GO:0097114	NMDA glutamate receptor clustering(GO:0097114)
26.0	78.0	GO:0033693	neurofilament bundle assembly(GO:0033693)
25.9	77.8	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
25.9	77.7	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
24.6	172.3	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
24.5	122.3	GO:0035063	nuclear speck organization(GO:0035063)
23.9	23.9	GO:0070314	G1 to G0 transition(GO:0070314)
23.6	70.9	GO:0070830	bicellular tight junction assembly(GO:0070830)
23.6	94.3	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
23.0	69.0	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
22.9	91.7	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
22.9	160.0	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
22.6	22.6	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
22.3	89.4	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
22.1	44.2	GO:0072237	metanephric proximal tubule development(GO:0072237)
21.8	87.0	GO:1904565	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
21.7	65.1	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
21.6	64.9	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
21.5	129.1	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
21.2	106.0	GO:0090272	negative regulation of fibroblast growth factor production(GO:0090272)
21.1	42.3	GO:0045921	positive regulation of exocytosis(GO:0045921)
21.1	84.6	GO:0042412	taurine biosynthetic process(GO:0042412)
20.3	61.0	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
20.2	20.2	GO:0060352	cell adhesion molecule production(GO:0060352) regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
20.1	261.2	GO:2001135	regulation of endocytic recycling(GO:2001135)
19.7	118.1	GO:0071321	cellular response to cGMP(GO:0071321)
19.5	58.6	GO:2000705	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
19.4	38.8	GO:0072134	nephrogenic mesenchyme morphogenesis(GO:0072134)
18.7	37.3	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
18.3	18.3	GO:0050884	neuromuscular process controlling posture(GO:0050884)
18.1	54.4	GO:2000182	regulation of progesterone biosynthetic process(GO:2000182)
18.0	72.2	GO:0060594	mammary gland specification(GO:0060594)
18.0	251.3	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
17.8	231.4	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
17.8	88.8	GO:0006041	glucosamine metabolic process(GO:0006041)
17.7	17.7	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
17.6	52.8	GO:0021718	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
17.6	17.6	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
17.5	209.8	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
17.1	68.4	GO:0048496	maintenance of organ identity(GO:0048496)
17.1	17.1	GO:2000591	negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) cell migration involved in kidney development(GO:0035787) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
16.9	67.5	GO:0019086	late viral transcription(GO:0019086)
16.8	16.8	GO:1903350	response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
16.8	50.4	GO:1904647	response to rotenone(GO:1904647)
16.7	33.4	GO:0014898	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
16.5	49.6	GO:0008355	olfactory learning(GO:0008355)
16.5	164.9	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
16.3	162.7	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
16.2	81.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
16.1	64.4	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
16.1	48.3	GO:1902534	single-organism membrane invagination(GO:1902534)
16.1	96.4	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
16.0	16.0	GO:0075071	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
16.0	16.0	GO:0007518	myoblast fate determination(GO:0007518)
15.9	31.8	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
15.9	111.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
15.6	62.5	GO:0060313	negative regulation of blood vessel remodeling(GO:0060313)
15.3	15.3	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763)
15.3	15.3	GO:1902809	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
15.3	76.6	GO:0097091	synaptic vesicle clustering(GO:0097091)
15.2	45.7	GO:0048687	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
14.9	14.9	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
14.9	44.8	GO:1990502	dense core granule maturation(GO:1990502)
14.9	14.9	GO:0002265	astrocyte activation involved in immune response(GO:0002265)
14.8	44.4	GO:1903401	L-lysine transmembrane transport(GO:1903401)
14.7	58.8	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
14.5	58.2	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
14.4	72.1	GO:0061107	seminal vesicle development(GO:0061107)
14.4	43.2	GO:0032474	otolith morphogenesis(GO:0032474)
14.4	14.4	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
14.3	57.4	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
14.3	14.3	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
14.3	71.3	GO:0015670	carbon dioxide transport(GO:0015670)
14.3	14.3	GO:1903059	regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
14.1	56.5	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
14.1	112.8	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
14.1	126.8	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
14.1	70.4	GO:0016476	regulation of embryonic cell shape(GO:0016476)
13.9	83.7	GO:0033504	floor plate development(GO:0033504)
13.9	41.8	GO:0060437	lung growth(GO:0060437)
13.9	41.8	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
13.8	55.1	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
13.7	27.5	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
13.7	96.0	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
13.7	41.1	GO:0003358	noradrenergic neuron development(GO:0003358)
13.6	13.6	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
13.4	53.5	GO:1990535	neuron projection maintenance(GO:1990535)
13.3	13.3	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
13.3	39.9	GO:1990504	dense core granule exocytosis(GO:1990504)
13.3	79.7	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
13.2	131.8	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
13.1	52.6	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
13.1	105.1	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
13.0	78.2	GO:0018095	protein polyglutamylation(GO:0018095)
12.9	38.8	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
12.9	51.6	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
12.9	103.1	GO:0033578	protein glycosylation in Golgi(GO:0033578)
12.9	51.5	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
12.8	38.3	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
12.5	25.0	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
12.4	24.8	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
12.4	86.7	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
12.3	37.0	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
12.3	36.9	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
12.3	12.3	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
12.1	60.7	GO:0036369	transcription factor catabolic process(GO:0036369)
12.0	36.0	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
12.0	36.0	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
12.0	59.9	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
12.0	83.8	GO:1903818	positive regulation of voltage-gated potassium channel activity(GO:1903818)
11.9	35.8	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
11.9	11.9	GO:0014075	response to amine(GO:0014075)
11.8	11.8	GO:0072520	seminiferous tubule development(GO:0072520)
11.8	35.4	GO:0051595	response to methylglyoxal(GO:0051595)
11.8	105.9	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
11.7	35.2	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
11.7	46.9	GO:0048749	compound eye development(GO:0048749)
11.7	35.1	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
11.7	46.7	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
11.7	35.0	GO:1904328	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
11.6	58.0	GO:1902075	cellular response to salt(GO:1902075)
11.6	34.7	GO:1902530	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
11.5	57.7	GO:0060024	rhythmic synaptic transmission(GO:0060024)
11.5	22.9	GO:0072014	proximal tubule development(GO:0072014)
11.4	79.8	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
11.4	11.4	GO:0060544	regulation of necroptotic process(GO:0060544)
11.2	44.9	GO:0034959	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
11.2	44.8	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
11.2	67.0	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
11.2	11.2	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
11.1	33.3	GO:0070781	response to biotin(GO:0070781)
11.1	77.4	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
11.1	33.2	GO:0007602	phototransduction(GO:0007602)
11.0	43.9	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
10.9	65.7	GO:2001224	positive regulation of neuron migration(GO:2001224)
10.9	21.7	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
10.8	21.6	GO:0097477	spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
10.8	32.4	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
10.8	107.8	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
10.8	21.6	GO:0009386	translational attenuation(GO:0009386)
10.8	10.8	GO:0015870	acetylcholine transport(GO:0015870)
10.8	96.9	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
10.7	10.7	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
10.7	21.4	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
10.7	21.4	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
10.7	53.3	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
10.6	31.8	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
10.6	179.7	GO:0019371	cyclooxygenase pathway(GO:0019371)
10.5	137.1	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
10.5	42.0	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
10.5	41.8	GO:1904978	regulation of endosome organization(GO:1904978)
10.4	83.4	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664)
10.4	41.6	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
10.4	41.6	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
10.4	41.6	GO:0072143	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
10.4	10.4	GO:0060214	endocardium formation(GO:0060214)
10.4	51.8	GO:0051013	microtubule severing(GO:0051013)
10.3	51.5	GO:0043589	skin morphogenesis(GO:0043589)
10.3	20.6	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
10.3	267.3	GO:0071294	cellular response to zinc ion(GO:0071294)
10.3	51.4	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
10.3	20.5	GO:2001202	negative regulation of transforming growth factor-beta secretion(GO:2001202)
10.2	30.7	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
10.2	10.2	GO:0051138	positive regulation of NK T cell differentiation(GO:0051138)
10.2	51.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
10.1	40.5	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
10.1	161.4	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
10.1	40.3	GO:0005986	sucrose biosynthetic process(GO:0005986)
10.1	30.2	GO:1990108	protein linear deubiquitination(GO:1990108)
10.0	50.1	GO:0070829	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
10.0	60.1	GO:0042415	norepinephrine metabolic process(GO:0042415)
10.0	10.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
9.9	69.6	GO:0043117	positive regulation of vascular permeability(GO:0043117)
9.9	9.9	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
9.8	19.7	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
9.8	177.1	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
9.8	49.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
9.8	49.0	GO:0015961	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
9.7	58.3	GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
9.7	29.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
9.7	96.9	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
9.7	57.9	GO:0055059	asymmetric neuroblast division(GO:0055059)
9.7	48.3	GO:0016080	synaptic vesicle targeting(GO:0016080)
9.6	86.8	GO:0048266	behavioral response to pain(GO:0048266)
9.6	28.8	GO:0051946	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
9.6	28.8	GO:0032888	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
9.6	48.0	GO:0071874	response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
9.5	19.0	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
9.5	19.0	GO:1904031	positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
9.5	247.4	GO:0034199	activation of protein kinase A activity(GO:0034199)
9.5	9.5	GO:0097017	renal protein absorption(GO:0097017)
9.4	253.5	GO:0048268	clathrin coat assembly(GO:0048268)
9.4	37.4	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
9.4	28.1	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
9.3	121.5	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
9.3	18.7	GO:0060086	circadian temperature homeostasis(GO:0060086)
9.3	83.6	GO:1902949	positive regulation of tau-protein kinase activity(GO:1902949)
9.2	46.2	GO:0048680	positive regulation of axon regeneration(GO:0048680)
9.2	18.4	GO:0042026	protein refolding(GO:0042026)
9.2	36.8	GO:0071279	cellular response to cobalt ion(GO:0071279)
9.2	36.8	GO:0042713	sperm ejaculation(GO:0042713)
9.2	45.9	GO:1903273	regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
9.2	82.6	GO:0072102	glomerulus morphogenesis(GO:0072102)
9.2	9.2	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
9.1	18.3	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
9.0	36.2	GO:0060385	axonogenesis involved in innervation(GO:0060385)
8.9	8.9	GO:0098773	skin epidermis development(GO:0098773)
8.9	35.8	GO:2001023	regulation of response to drug(GO:2001023)
8.9	8.9	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
8.9	35.6	GO:0030807	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
8.9	204.3	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
8.9	35.5	GO:0051866	general adaptation syndrome(GO:0051866)
8.8	79.5	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
8.8	70.5	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
8.8	8.8	GO:0045792	negative regulation of cell size(GO:0045792)
8.8	79.1	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
8.8	131.5	GO:0015669	gas transport(GO:0015669)
8.8	8.8	GO:0009649	entrainment of circadian clock(GO:0009649)
8.7	8.7	GO:0021854	hypothalamus development(GO:0021854)
8.7	52.2	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
8.7	95.7	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
8.7	69.6	GO:0007258	JUN phosphorylation(GO:0007258)
8.7	34.7	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
8.7	43.4	GO:0016322	neuron remodeling(GO:0016322)
8.7	52.0	GO:0046208	spermine catabolic process(GO:0046208)
8.7	51.9	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
8.6	43.1	GO:0030070	insulin processing(GO:0030070)
8.6	25.8	GO:0071529	cementum mineralization(GO:0071529)
8.6	8.6	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
8.6	266.7	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
8.6	34.4	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
8.6	34.3	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
8.6	25.7	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
8.6	34.3	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
8.6	25.7	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
8.6	34.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
8.5	42.7	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
8.5	59.7	GO:1902669	positive regulation of axon guidance(GO:1902669)
8.5	102.0	GO:0046325	negative regulation of glucose import(GO:0046325)
8.5	25.4	GO:0021886	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
8.5	33.8	GO:1905232	cellular response to L-glutamate(GO:1905232)
8.4	16.8	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
8.4	67.3	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
8.4	16.7	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
8.4	167.2	GO:0032011	ARF protein signal transduction(GO:0032011)
8.3	25.0	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
8.3	16.6	GO:0038034	signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
8.3	33.2	GO:0072139	glomerular parietal epithelial cell differentiation(GO:0072139)
8.3	8.3	GO:2000364	regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
8.2	115.1	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
8.2	81.8	GO:0042711	maternal behavior(GO:0042711) parental behavior(GO:0060746)
8.1	24.4	GO:0061760	antifungal innate immune response(GO:0061760)
8.1	48.8	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
8.1	24.3	GO:0010046	response to mycotoxin(GO:0010046)
8.1	72.9	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
8.1	8.1	GO:0023035	CD40 signaling pathway(GO:0023035)
8.1	40.3	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
8.0	16.1	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
8.0	72.0	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
8.0	16.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
8.0	8.0	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
8.0	8.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
7.9	7.9	GO:1900027	regulation of ruffle assembly(GO:1900027)
7.9	63.6	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
7.9	55.5	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
7.9	63.2	GO:0032482	Rab protein signal transduction(GO:0032482)
7.9	7.9	GO:0007412	axon target recognition(GO:0007412)
7.9	55.1	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
7.9	15.7	GO:0045925	positive regulation of female receptivity(GO:0045925)
7.9	70.8	GO:0015871	choline transport(GO:0015871)
7.9	7.9	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
7.8	7.8	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
7.8	7.8	GO:0007521	muscle cell fate determination(GO:0007521)
7.8	23.3	GO:1905073	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
7.7	30.9	GO:0046958	nonassociative learning(GO:0046958)
7.7	331.8	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
7.7	30.9	GO:0071494	cellular response to UV-C(GO:0071494)
7.7	30.8	GO:0097676	histone H3-K36 dimethylation(GO:0097676)
7.7	7.7	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
7.7	53.6	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
7.6	22.8	GO:0046351	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) disaccharide biosynthetic process(GO:0046351)
7.6	30.3	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
7.6	7.6	GO:0055096	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
7.6	7.6	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
7.6	22.7	GO:0009183	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
7.5	45.2	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
7.5	75.3	GO:0036066	protein O-linked fucosylation(GO:0036066)
7.5	180.1	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
7.5	217.4	GO:0008045	motor neuron axon guidance(GO:0008045)
7.5	82.4	GO:0001886	endothelial cell morphogenesis(GO:0001886)
7.5	15.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
7.5	7.5	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
7.5	37.3	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
7.5	7.5	GO:0001743	optic placode formation(GO:0001743)
7.5	74.5	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
7.5	37.3	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
7.4	14.9	GO:0090187	positive regulation of pancreatic juice secretion(GO:0090187)
7.4	29.8	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
7.4	7.4	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
7.4	96.0	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
7.4	44.3	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
7.3	22.0	GO:0045212	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
7.3	43.9	GO:0060137	maternal process involved in parturition(GO:0060137)
7.3	43.9	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
7.3	29.2	GO:0061734	parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
7.3	21.9	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
7.3	131.2	GO:0034389	lipid particle organization(GO:0034389)
7.3	65.4	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
7.3	7.3	GO:0038003	opioid receptor signaling pathway(GO:0038003)
7.3	14.5	GO:0042360	vitamin E metabolic process(GO:0042360)
7.2	21.7	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
7.2	7.2	GO:0042560	folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
7.2	21.6	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
7.2	43.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
7.2	14.4	GO:0001842	neural fold formation(GO:0001842)
7.2	14.4	GO:0021781	glial cell fate commitment(GO:0021781)
7.2	35.9	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
7.2	114.6	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
7.2	43.0	GO:0002175	protein localization to paranode region of axon(GO:0002175)
7.2	21.5	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
7.2	50.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
7.1	21.3	GO:0061744	motor behavior(GO:0061744)
7.1	14.2	GO:0061053	somite development(GO:0061053)
7.1	7.1	GO:0035725	sodium ion transmembrane transport(GO:0035725)
7.1	21.2	GO:0048243	norepinephrine secretion(GO:0048243)
7.0	56.3	GO:0038007	netrin-activated signaling pathway(GO:0038007)
7.0	7.0	GO:0003417	growth plate cartilage development(GO:0003417)
7.0	35.2	GO:0032383	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
7.0	14.0	GO:1903509	glycolipid metabolic process(GO:0006664) liposaccharide metabolic process(GO:1903509)
7.0	188.8	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
7.0	118.6	GO:0035988	chondrocyte proliferation(GO:0035988)
7.0	48.8	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
7.0	62.6	GO:0007413	axonal fasciculation(GO:0007413)
7.0	83.4	GO:0070050	neuron cellular homeostasis(GO:0070050)
6.9	27.8	GO:0035633	maintenance of blood-brain barrier(GO:0035633)
6.9	27.8	GO:1900154	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
6.9	6.9	GO:0097084	vascular smooth muscle cell development(GO:0097084)
6.9	20.7	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
6.9	34.5	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
6.9	20.6	GO:0006566	threonine metabolic process(GO:0006566)
6.8	6.8	GO:1903527	regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
6.8	20.5	GO:0071409	cellular response to cycloheximide(GO:0071409)
6.8	54.6	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
6.8	68.2	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
6.8	13.6	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
6.8	47.5	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
6.8	20.3	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
6.7	40.4	GO:0006526	arginine biosynthetic process(GO:0006526)
6.7	20.2	GO:0090649	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
6.7	13.4	GO:0051446	positive regulation of meiotic cell cycle(GO:0051446)
6.7	33.6	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
6.7	13.4	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
6.7	33.5	GO:0021578	hindbrain maturation(GO:0021578) central nervous system maturation(GO:0021626)
6.7	39.9	GO:0060453	regulation of gastric acid secretion(GO:0060453)
6.6	252.4	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
6.6	106.2	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
6.6	33.2	GO:0070384	Harderian gland development(GO:0070384)
6.6	26.5	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
6.6	19.9	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
6.6	6.6	GO:0014002	astrocyte development(GO:0014002)
6.6	26.2	GO:0070426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
6.5	45.8	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
6.5	19.6	GO:0043116	negative regulation of vascular permeability(GO:0043116)
6.5	32.5	GO:0006127	glycerophosphate shuttle(GO:0006127)
6.5	13.0	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
6.5	32.5	GO:0048807	female genitalia morphogenesis(GO:0048807)
6.5	45.4	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
6.5	13.0	GO:1901160	primary amino compound metabolic process(GO:1901160)
6.5	6.5	GO:2000824	negative regulation of androgen receptor activity(GO:2000824)
6.5	12.9	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
6.5	19.4	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
6.4	38.6	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
6.4	32.1	GO:1904100	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
6.4	19.2	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
6.4	51.3	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
6.4	19.1	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
6.3	95.2	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
6.3	88.7	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
6.3	12.7	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
6.3	44.0	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
6.2	31.2	GO:0003322	pancreatic A cell development(GO:0003322)
6.2	12.5	GO:1990164	histone H2A phosphorylation(GO:1990164)
6.2	6.2	GO:0010266	response to vitamin B1(GO:0010266)
6.2	31.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
6.2	24.8	GO:0034334	adherens junction maintenance(GO:0034334)
6.2	43.4	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
6.2	12.4	GO:0042940	D-amino acid transport(GO:0042940)
6.2	18.6	GO:0055072	iron ion homeostasis(GO:0055072)
6.2	18.5	GO:0032364	oxygen homeostasis(GO:0032364)
6.2	6.2	GO:1902369	negative regulation of RNA catabolic process(GO:1902369) negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
6.2	12.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
6.2	73.9	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
6.1	42.9	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
6.1	12.3	GO:0003219	cardiac right ventricle formation(GO:0003219)
6.1	18.3	GO:0023021	termination of signal transduction(GO:0023021)
6.1	18.2	GO:0060081	membrane hyperpolarization(GO:0060081)
6.1	97.3	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
6.1	91.1	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
6.0	30.1	GO:0000189	MAPK import into nucleus(GO:0000189)
6.0	144.4	GO:0045494	photoreceptor cell maintenance(GO:0045494)
6.0	6.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
6.0	72.2	GO:0021794	thalamus development(GO:0021794)
6.0	6.0	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
6.0	12.0	GO:0060013	righting reflex(GO:0060013)
6.0	6.0	GO:0015808	L-alanine transport(GO:0015808)
6.0	42.0	GO:1904354	negative regulation of telomere capping(GO:1904354)
6.0	54.0	GO:0042373	vitamin K metabolic process(GO:0042373)
6.0	18.0	GO:0098935	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
6.0	29.9	GO:1901731	positive regulation of platelet aggregation(GO:1901731)
6.0	59.8	GO:0006983	ER overload response(GO:0006983)
6.0	17.9	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
6.0	190.9	GO:0014003	oligodendrocyte development(GO:0014003)
6.0	166.8	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
6.0	11.9	GO:0007231	osmosensory signaling pathway(GO:0007231)
5.9	29.7	GO:1900107	regulation of nodal signaling pathway(GO:1900107)
5.9	11.7	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
5.8	5.8	GO:0003338	metanephros morphogenesis(GO:0003338)
5.8	11.6	GO:0002513	tolerance induction to self antigen(GO:0002513)
5.8	23.2	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
5.8	23.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
5.8	17.3	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
5.8	11.5	GO:0060033	anatomical structure regression(GO:0060033)
5.8	5.8	GO:1904933	regulation of cell proliferation in midbrain(GO:1904933)
5.7	11.5	GO:0061245	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) establishment or maintenance of bipolar cell polarity(GO:0061245)
5.7	34.5	GO:0098535	de novo centriole assembly(GO:0098535)
5.7	17.2	GO:0045957	regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
5.7	34.4	GO:0071105	response to interleukin-11(GO:0071105)
5.7	51.5	GO:0007042	lysosomal lumen acidification(GO:0007042)
5.7	5.7	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
5.7	28.4	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
5.7	85.1	GO:2000505	regulation of energy homeostasis(GO:2000505)
5.7	11.3	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
5.7	147.4	GO:0097503	sialylation(GO:0097503)
5.7	17.0	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
5.7	17.0	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
5.7	5.7	GO:0031860	telomeric 3' overhang formation(GO:0031860)
5.6	22.6	GO:0003352	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
5.6	33.8	GO:0008090	retrograde axonal transport(GO:0008090)
5.6	39.4	GO:0070544	histone H3-K36 demethylation(GO:0070544)
5.6	22.5	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) mesonephric duct morphogenesis(GO:0072180)
5.6	33.7	GO:0032025	response to cobalt ion(GO:0032025)
5.6	22.4	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
5.6	100.8	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
5.6	5.6	GO:0071168	protein localization to chromatin(GO:0071168)
5.6	5.6	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
5.5	22.2	GO:0018094	protein polyglycylation(GO:0018094)
5.5	5.5	GO:0007440	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
5.5	5.5	GO:0035801	adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
5.5	11.0	GO:0071711	basement membrane organization(GO:0071711)
5.5	11.0	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
5.5	44.0	GO:0086070	SA node cell to atrial cardiac muscle cell communication(GO:0086070)
5.5	5.5	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
5.5	5.5	GO:1902310	positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
5.5	16.4	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
5.4	38.0	GO:0009597	detection of virus(GO:0009597)
5.4	16.2	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
5.4	10.8	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
5.4	53.9	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
5.4	37.7	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
5.4	102.1	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
5.4	21.4	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
5.3	26.7	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
5.3	5.3	GO:0051885	positive regulation of anagen(GO:0051885)
5.3	10.7	GO:2000463	positive regulation of excitatory postsynaptic potential(GO:2000463)
5.3	10.7	GO:0070257	positive regulation of mucus secretion(GO:0070257)
5.3	5.3	GO:1900048	positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
5.3	16.0	GO:0034227	tRNA thio-modification(GO:0034227)
5.3	10.6	GO:0021891	olfactory bulb interneuron development(GO:0021891)
5.3	10.6	GO:1900673	olefin metabolic process(GO:1900673)
5.3	5.3	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
5.3	37.2	GO:1901387	positive regulation of voltage-gated calcium channel activity(GO:1901387)
5.3	31.7	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
5.3	15.8	GO:0051414	response to cortisol(GO:0051414)
5.3	15.8	GO:0001172	transcription, RNA-templated(GO:0001172)
5.3	15.8	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
5.3	5.3	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
5.2	5.2	GO:0030890	positive regulation of B cell proliferation(GO:0030890)
5.2	10.5	GO:0090427	activation of meiosis(GO:0090427)
5.2	89.1	GO:0030539	male genitalia development(GO:0030539)
5.2	31.4	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
5.2	78.3	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
5.2	15.7	GO:0007497	posterior midgut development(GO:0007497)
5.2	10.4	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
5.2	15.7	GO:0043507	positive regulation of JUN kinase activity(GO:0043507)
5.2	15.6	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
5.2	20.8	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
5.2	20.8	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
5.2	10.4	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
5.2	10.4	GO:0051944	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
5.2	56.9	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
5.1	36.0	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
5.1	41.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
5.1	15.4	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
5.1	25.6	GO:0060346	bone trabecula formation(GO:0060346)
5.1	5.1	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
5.1	10.2	GO:0051969	regulation of transmission of nerve impulse(GO:0051969)
5.1	35.8	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
5.1	61.3	GO:0021681	cerebellar granular layer development(GO:0021681)
5.1	25.5	GO:0021819	layer formation in cerebral cortex(GO:0021819)
5.1	5.1	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
5.1	71.3	GO:0001946	lymphangiogenesis(GO:0001946)
5.1	5.1	GO:2000617	positive regulation of histone H3-K9 acetylation(GO:2000617)
5.1	5.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
5.1	10.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
5.1	20.3	GO:0042335	cuticle development(GO:0042335)
5.0	10.1	GO:0050777	negative regulation of immune response(GO:0050777)
5.0	20.2	GO:0010829	negative regulation of glucose transport(GO:0010829)
5.0	25.1	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
5.0	5.0	GO:0070471	uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
5.0	75.1	GO:0021954	central nervous system neuron development(GO:0021954)
5.0	5.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
5.0	5.0	GO:2000078	glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
5.0	5.0	GO:2000584	regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
5.0	29.7	GO:0006287	base-excision repair, gap-filling(GO:0006287)
5.0	74.3	GO:0010457	centriole-centriole cohesion(GO:0010457)
4.9	14.8	GO:0072244	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
4.9	137.9	GO:0043984	histone H4-K16 acetylation(GO:0043984)
4.9	39.3	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
4.9	4.9	GO:0035963	cellular response to interleukin-13(GO:0035963)
4.9	4.9	GO:0061743	motor learning(GO:0061743)
4.9	9.7	GO:0010959	regulation of metal ion transport(GO:0010959)
4.8	43.6	GO:1901978	positive regulation of cell cycle checkpoint(GO:1901978)
4.8	4.8	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
4.8	29.0	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
4.8	14.5	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
4.8	14.5	GO:0035610	protein side chain deglutamylation(GO:0035610)
4.8	24.0	GO:0035617	stress granule disassembly(GO:0035617)
4.8	33.5	GO:0098655	cation transmembrane transport(GO:0098655)
4.8	76.6	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
4.8	19.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
4.8	4.8	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
4.7	9.5	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
4.7	37.8	GO:0034380	high-density lipoprotein particle assembly(GO:0034380)
4.7	14.2	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
4.7	4.7	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
4.7	4.7	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
4.7	23.3	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
4.6	18.6	GO:0060294	cilium movement involved in cell motility(GO:0060294)
4.6	9.3	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
4.6	23.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
4.6	41.7	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
4.6	129.6	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
4.6	23.1	GO:0099551	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
4.6	4.6	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
4.6	9.2	GO:0031959	mineralocorticoid receptor signaling pathway(GO:0031959)
4.6	4.6	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
4.6	224.1	GO:0015701	bicarbonate transport(GO:0015701)
4.5	45.5	GO:0060022	hard palate development(GO:0060022)
4.5	4.5	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
4.5	68.2	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
4.5	68.1	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
4.5	9.1	GO:0021592	fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
4.5	13.6	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
4.5	4.5	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
4.5	9.0	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
4.5	72.3	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
4.5	58.6	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
4.5	9.0	GO:2000535	regulation of entry of bacterium into host cell(GO:2000535)
4.5	13.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
4.5	22.4	GO:0030517	negative regulation of axon extension(GO:0030517)
4.5	40.2	GO:0051410	detoxification of nitrogen compound(GO:0051410)
4.5	44.6	GO:0060068	vagina development(GO:0060068)
4.5	151.6	GO:0050885	neuromuscular process controlling balance(GO:0050885)
4.5	8.9	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
4.5	182.5	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
4.4	17.8	GO:0010650	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
4.4	44.5	GO:0001504	neurotransmitter uptake(GO:0001504)
4.4	26.6	GO:0034776	response to histamine(GO:0034776)
4.4	8.9	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
4.4	52.9	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
4.4	13.2	GO:1903625	negative regulation of DNA catabolic process(GO:1903625)
4.4	4.4	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
4.4	26.3	GO:0016191	synaptic vesicle uncoating(GO:0016191)
4.4	8.8	GO:0006982	response to lipid hydroperoxide(GO:0006982)
4.4	17.6	GO:1902018	negative regulation of cilium assembly(GO:1902018)
4.4	26.2	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
4.3	13.0	GO:1900073	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
4.3	8.7	GO:0006665	sphingolipid metabolic process(GO:0006665)
4.3	73.6	GO:0042417	dopamine metabolic process(GO:0042417)
4.3	17.3	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
4.3	13.0	GO:1990403	embryonic brain development(GO:1990403)
4.3	17.3	GO:0097035	regulation of membrane lipid distribution(GO:0097035)
4.3	17.3	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
4.3	12.9	GO:0090009	primitive streak formation(GO:0090009)
4.3	12.9	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
4.3	17.2	GO:2000018	regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020)
4.3	34.3	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
4.3	12.9	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
4.3	47.0	GO:0008038	neuron recognition(GO:0008038)
4.3	51.1	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
4.3	8.5	GO:2001186	regulation of T cell antigen processing and presentation(GO:0002625) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
4.3	12.8	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
4.2	127.5	GO:0019228	neuronal action potential(GO:0019228)
4.2	21.2	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
4.2	16.9	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
4.2	33.8	GO:0030516	regulation of axon extension(GO:0030516)
4.2	8.5	GO:0060075	regulation of resting membrane potential(GO:0060075)
4.2	33.8	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
4.2	4.2	GO:0042048	olfactory behavior(GO:0042048)
4.2	12.6	GO:0043171	peptide catabolic process(GO:0043171)
4.2	12.6	GO:0032074	negative regulation of nuclease activity(GO:0032074)
4.2	16.7	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
4.2	58.4	GO:2000291	regulation of myoblast proliferation(GO:2000291)
4.2	4.2	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
4.2	4.2	GO:0060157	urinary bladder development(GO:0060157)
4.2	78.9	GO:0006895	Golgi to endosome transport(GO:0006895)
4.1	107.5	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
4.1	24.8	GO:0002098	tRNA wobble uridine modification(GO:0002098)
4.1	24.8	GO:0008088	axo-dendritic transport(GO:0008088)
4.1	8.2	GO:1904430	negative regulation of t-circle formation(GO:1904430)
4.1	78.1	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
4.1	28.7	GO:0042574	retinal metabolic process(GO:0042574)
4.1	49.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
4.1	36.7	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
4.1	28.5	GO:1900449	regulation of glutamate receptor signaling pathway(GO:1900449)
4.1	60.8	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
4.0	8.1	GO:0051684	maintenance of Golgi location(GO:0051684)
4.0	16.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
4.0	12.0	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
4.0	24.0	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
4.0	8.0	GO:0050679	positive regulation of epithelial cell proliferation(GO:0050679)
4.0	4.0	GO:0030432	peristalsis(GO:0030432)
4.0	15.8	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
3.9	3.9	GO:2001225	regulation of chloride transport(GO:2001225)
3.9	19.6	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
3.9	7.8	GO:0036159	inner dynein arm assembly(GO:0036159)
3.9	3.9	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
3.9	23.3	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
3.9	11.6	GO:0003416	endochondral bone growth(GO:0003416)
3.9	7.8	GO:0060113	inner ear receptor cell differentiation(GO:0060113)
3.9	11.6	GO:0070459	prolactin secretion(GO:0070459)
3.9	11.6	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
3.8	19.2	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
3.8	30.6	GO:0010172	embryonic body morphogenesis(GO:0010172)
3.8	11.4	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
3.8	34.0	GO:0021756	striatum development(GO:0021756)
3.8	15.0	GO:0032496	response to lipopolysaccharide(GO:0032496)
3.8	3.8	GO:0060290	transdifferentiation(GO:0060290)
3.7	7.5	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
3.7	15.0	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
3.7	29.8	GO:0090042	tubulin deacetylation(GO:0090042)
3.7	29.8	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
3.7	3.7	GO:2001293	malonyl-CoA metabolic process(GO:2001293)
3.7	3.7	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
3.7	11.1	GO:0048485	sympathetic nervous system development(GO:0048485)
3.7	22.3	GO:0007256	activation of JNKK activity(GO:0007256)
3.7	66.7	GO:0050901	leukocyte tethering or rolling(GO:0050901)
3.7	18.5	GO:0051012	microtubule sliding(GO:0051012)
3.7	225.0	GO:1902476	chloride transmembrane transport(GO:1902476)
3.7	3.7	GO:0032607	interferon-alpha production(GO:0032607)
3.7	3.7	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005)
3.7	18.4	GO:0021978	telencephalon regionalization(GO:0021978)
3.7	3.7	GO:0002437	inflammatory response to antigenic stimulus(GO:0002437)
3.7	55.2	GO:0097484	dendrite extension(GO:0097484)
3.7	11.0	GO:0060151	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
3.7	11.0	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
3.7	11.0	GO:0021514	ventral spinal cord interneuron differentiation(GO:0021514)
3.7	3.7	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
3.7	14.6	GO:0090160	Golgi to lysosome transport(GO:0090160)
3.7	11.0	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
3.6	10.9	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
3.6	7.3	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
3.6	7.3	GO:0071442	regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
3.6	18.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
3.6	10.9	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
3.6	7.2	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
3.6	10.8	GO:0035524	proline transmembrane transport(GO:0035524)
3.6	3.6	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
3.6	82.3	GO:0003254	regulation of membrane depolarization(GO:0003254)
3.6	7.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
3.6	3.6	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
3.5	31.9	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
3.5	7.1	GO:0036018	cellular response to erythropoietin(GO:0036018)
3.5	10.6	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
3.5	10.6	GO:0006821	chloride transport(GO:0006821)
3.5	105.9	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
3.5	28.1	GO:0006069	ethanol oxidation(GO:0006069)
3.5	14.0	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
3.5	10.5	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
3.5	17.5	GO:0048011	neurotrophin TRK receptor signaling pathway(GO:0048011)
3.5	3.5	GO:0097490	sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
3.5	20.8	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
3.5	20.8	GO:0030322	stabilization of membrane potential(GO:0030322)
3.5	3.5	GO:0051604	protein maturation(GO:0051604)
3.5	27.7	GO:0097062	dendritic spine maintenance(GO:0097062)
3.5	51.9	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
3.4	17.2	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
3.4	51.6	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
3.4	44.6	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
3.4	17.2	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
3.4	13.7	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
3.4	6.8	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
3.4	23.9	GO:0048820	hair follicle maturation(GO:0048820)
3.4	17.0	GO:0019323	pentose catabolic process(GO:0019323)
3.4	85.0	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
3.4	13.6	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
3.4	64.5	GO:0010107	potassium ion import(GO:0010107)
3.4	16.9	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
3.4	10.1	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
3.4	3.4	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
3.4	20.2	GO:0016075	rRNA catabolic process(GO:0016075)
3.3	10.0	GO:1902510	regulation of apoptotic DNA fragmentation(GO:1902510)
3.3	56.7	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
3.3	3.3	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
3.3	26.6	GO:0001778	plasma membrane repair(GO:0001778)
3.3	16.6	GO:0042118	endothelial cell activation(GO:0042118)
3.3	19.9	GO:0007135	meiosis II(GO:0007135)
3.3	6.6	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
3.3	16.4	GO:0032007	negative regulation of TOR signaling(GO:0032007)
3.3	19.6	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
3.3	35.9	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
3.3	6.5	GO:0030916	otic vesicle formation(GO:0030916)
3.3	13.0	GO:0001661	conditioned taste aversion(GO:0001661)
3.3	13.0	GO:0048102	autophagic cell death(GO:0048102)
3.2	19.5	GO:0051694	pointed-end actin filament capping(GO:0051694)
3.2	3.2	GO:0048841	regulation of axon extension involved in axon guidance(GO:0048841)
3.2	9.6	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
3.2	16.0	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
3.2	22.4	GO:0007506	gonadal mesoderm development(GO:0007506)
3.2	25.6	GO:0015919	peroxisomal membrane transport(GO:0015919)
3.2	12.8	GO:0015705	iodide transport(GO:0015705)
3.2	12.8	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
3.2	19.2	GO:0035457	cellular response to interferon-alpha(GO:0035457)
3.2	3.2	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
3.2	12.7	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
3.2	3.2	GO:0051547	regulation of keratinocyte migration(GO:0051547)
3.2	12.6	GO:0045739	positive regulation of DNA repair(GO:0045739)
3.2	3.2	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
3.1	22.0	GO:0015791	polyol transport(GO:0015791)
3.1	9.4	GO:1903244	positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
3.1	28.2	GO:0036158	outer dynein arm assembly(GO:0036158)
3.1	22.0	GO:0016558	protein import into peroxisome matrix(GO:0016558)
3.1	6.2	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
3.1	3.1	GO:0055119	relaxation of cardiac muscle(GO:0055119)
3.1	12.4	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
3.1	12.4	GO:0072661	protein targeting to plasma membrane(GO:0072661)
3.1	24.8	GO:0035418	protein localization to synapse(GO:0035418)
3.1	15.4	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
3.1	9.2	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
3.1	49.2	GO:0035493	SNARE complex assembly(GO:0035493)
3.1	33.8	GO:0015886	heme transport(GO:0015886)
3.1	15.3	GO:0003096	renal sodium ion transport(GO:0003096)
3.1	6.1	GO:0072033	renal vesicle formation(GO:0072033) ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
3.1	9.2	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
3.0	12.2	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
3.0	21.3	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
3.0	9.1	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
3.0	3.0	GO:0072254	metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
3.0	9.1	GO:0071313	cellular response to caffeine(GO:0071313)
3.0	12.1	GO:1903597	negative regulation of gap junction assembly(GO:1903597)
3.0	6.0	GO:0043932	ossification involved in bone remodeling(GO:0043932)
3.0	15.1	GO:0097152	mesenchymal cell apoptotic process(GO:0097152)
3.0	21.1	GO:0018198	peptidyl-cysteine modification(GO:0018198)
3.0	12.1	GO:0043615	astrocyte cell migration(GO:0043615)
3.0	18.0	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
3.0	12.0	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
3.0	3.0	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
3.0	27.0	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
3.0	59.9	GO:0031167	rRNA methylation(GO:0031167)
3.0	27.0	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
3.0	18.0	GO:0048265	response to pain(GO:0048265)
3.0	20.9	GO:0021772	olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
3.0	32.8	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
3.0	20.9	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
3.0	6.0	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
3.0	14.9	GO:0019226	transmission of nerve impulse(GO:0019226)
3.0	11.9	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
3.0	151.4	GO:0035773	insulin secretion involved in cellular response to glucose stimulus(GO:0035773)
3.0	23.7	GO:0060856	establishment of blood-brain barrier(GO:0060856)
3.0	14.8	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
3.0	3.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
2.9	5.9	GO:0035696	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) positive regulation of monocyte extravasation(GO:2000439)
2.9	8.8	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
2.9	91.0	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
2.9	17.6	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
2.9	29.2	GO:0070633	transepithelial transport(GO:0070633)
2.9	26.2	GO:0006600	creatine metabolic process(GO:0006600)
2.9	40.6	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
2.9	20.3	GO:0043634	polyadenylation-dependent ncRNA catabolic process(GO:0043634)
2.9	17.4	GO:0071447	cellular response to hydroperoxide(GO:0071447)
2.9	20.1	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
2.9	11.5	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
2.9	2.9	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
2.9	2.9	GO:0046113	nucleobase catabolic process(GO:0046113)
2.9	11.4	GO:0051642	centrosome localization(GO:0051642)
2.8	5.7	GO:0042160	lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
2.8	8.5	GO:0002730	regulation of dendritic cell cytokine production(GO:0002730) negative regulation of dendritic cell cytokine production(GO:0002731)
2.8	8.5	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
2.8	11.3	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
2.8	76.2	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
2.8	8.5	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
2.8	2.8	GO:0051208	sequestering of calcium ion(GO:0051208)
2.8	112.7	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
2.8	109.8	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
2.8	28.1	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
2.8	11.2	GO:0018032	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
2.8	25.2	GO:0031112	positive regulation of microtubule polymerization or depolymerization(GO:0031112)
2.8	27.9	GO:0006776	vitamin A metabolic process(GO:0006776)
2.8	2.8	GO:0045112	integrin biosynthetic process(GO:0045112)
2.8	22.3	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
2.8	11.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
2.8	13.9	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
2.8	16.7	GO:1901525	negative regulation of macromitophagy(GO:1901525)
2.8	30.5	GO:0048251	elastic fiber assembly(GO:0048251)
2.8	19.4	GO:0051384	response to glucocorticoid(GO:0051384)
2.8	2.8	GO:0090298	negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
2.8	8.3	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
2.8	2.8	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684)
2.7	2.7	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
2.7	8.2	GO:0030324	lung development(GO:0030324)
2.7	10.9	GO:0034371	chylomicron remodeling(GO:0034371)
2.7	8.2	GO:0046950	cellular ketone body metabolic process(GO:0046950)
2.7	2.7	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
2.7	13.6	GO:0034472	snRNA 3'-end processing(GO:0034472)
2.7	5.4	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
2.7	32.5	GO:0007158	neuron cell-cell adhesion(GO:0007158)
2.7	13.5	GO:0043654	recognition of apoptotic cell(GO:0043654)
2.7	5.4	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
2.7	37.8	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
2.7	26.9	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
2.7	13.4	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
2.7	21.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
2.7	13.3	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
2.7	23.9	GO:0032411	positive regulation of transporter activity(GO:0032411)
2.7	34.5	GO:0055003	cardiac myofibril assembly(GO:0055003)
2.7	39.8	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
2.7	8.0	GO:0052203	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
2.6	7.8	GO:0061314	Notch signaling involved in heart development(GO:0061314)
2.6	10.4	GO:0045023	G0 to G1 transition(GO:0045023)
2.6	5.2	GO:0007548	sex differentiation(GO:0007548)
2.6	70.1	GO:0007257	activation of JUN kinase activity(GO:0007257)
2.6	77.7	GO:0016486	peptide hormone processing(GO:0016486)
2.6	5.2	GO:0021558	trochlear nerve development(GO:0021558)
2.6	10.3	GO:0018343	protein farnesylation(GO:0018343)
2.6	5.2	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
2.6	25.7	GO:0036465	synaptic vesicle recycling(GO:0036465)
2.6	5.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
2.6	20.5	GO:0072592	oxygen metabolic process(GO:0072592)
2.5	5.1	GO:0055099	response to high density lipoprotein particle(GO:0055099)
2.5	15.1	GO:0097205	renal filtration(GO:0097205)
2.5	7.5	GO:0072010	glomerular epithelium development(GO:0072010)
2.5	69.8	GO:0006783	heme biosynthetic process(GO:0006783)
2.5	14.9	GO:0043550	regulation of lipid kinase activity(GO:0043550)
2.5	2.5	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
2.5	24.6	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
2.4	205.4	GO:0006836	neurotransmitter transport(GO:0006836)
2.4	44.0	GO:0019372	lipoxygenase pathway(GO:0019372)
2.4	4.9	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
2.4	17.1	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
2.4	9.7	GO:0015811	L-cystine transport(GO:0015811)
2.4	14.5	GO:0030813	positive regulation of nucleotide catabolic process(GO:0030813)
2.4	2.4	GO:0001696	gastric acid secretion(GO:0001696)
2.4	2.4	GO:0050902	leukocyte adhesive activation(GO:0050902)
2.4	4.8	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
2.4	2.4	GO:0060023	soft palate development(GO:0060023)
2.4	19.3	GO:0050771	negative regulation of axonogenesis(GO:0050771)
2.4	7.2	GO:0045404	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
2.4	139.6	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
2.4	24.0	GO:0097435	fibril organization(GO:0097435)
2.4	9.6	GO:0031645	negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
2.4	2.4	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
2.4	33.5	GO:0071850	mitotic cell cycle arrest(GO:0071850)
2.4	4.8	GO:0002371	dendritic cell cytokine production(GO:0002371)
2.4	4.8	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
2.4	11.9	GO:1901660	calcium ion export(GO:1901660)
2.4	16.6	GO:0007512	adult heart development(GO:0007512)
2.4	14.2	GO:0035865	cellular response to potassium ion(GO:0035865)
2.4	80.5	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
2.4	30.8	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
2.4	9.4	GO:0006689	ganglioside catabolic process(GO:0006689)
2.4	9.4	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
2.4	18.8	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
2.3	2.3	GO:0061387	regulation of extent of cell growth(GO:0061387)
2.3	2.3	GO:1990637	response to prolactin(GO:1990637)
2.3	7.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
2.3	2.3	GO:0051167	glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
2.3	2.3	GO:0046061	dATP catabolic process(GO:0046061)
2.3	7.0	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
2.3	37.3	GO:0090140	regulation of mitochondrial fission(GO:0090140)
2.3	2.3	GO:0006533	aspartate catabolic process(GO:0006533)
2.3	16.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
2.3	16.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
2.3	38.9	GO:2000785	regulation of autophagosome assembly(GO:2000785)
2.3	52.3	GO:0001578	microtubule bundle formation(GO:0001578)
2.3	13.6	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
2.3	20.4	GO:0047496	vesicle transport along microtubule(GO:0047496)
2.3	6.8	GO:0048630	skeletal muscle tissue growth(GO:0048630)
2.2	9.0	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
2.2	2.2	GO:1990834	response to odorant(GO:1990834)
2.2	24.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
2.2	4.4	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
2.2	4.4	GO:0046068	cGMP metabolic process(GO:0046068)
2.2	22.2	GO:0030728	ovulation(GO:0030728)
2.2	20.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
2.2	111.0	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
2.2	13.3	GO:0048821	erythrocyte development(GO:0048821)
2.2	15.5	GO:0006685	sphingomyelin catabolic process(GO:0006685)
2.2	2.2	GO:2000677	regulation of transcription regulatory region DNA binding(GO:2000677)
2.2	2.2	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
2.2	19.8	GO:0048245	eosinophil chemotaxis(GO:0048245)
2.2	2.2	GO:0035634	response to stilbenoid(GO:0035634)
2.2	4.4	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
2.2	13.0	GO:0006537	glutamate biosynthetic process(GO:0006537)
2.2	34.7	GO:0048854	brain morphogenesis(GO:0048854)
2.2	8.7	GO:0003091	renal water homeostasis(GO:0003091)
2.2	4.3	GO:0032526	response to retinoic acid(GO:0032526)
2.2	8.6	GO:0035635	entry of bacterium into host cell(GO:0035635)
2.2	10.8	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
2.2	15.1	GO:0045007	depurination(GO:0045007)
2.1	2.1	GO:0035411	catenin import into nucleus(GO:0035411)
2.1	12.9	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
2.1	12.8	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
2.1	25.6	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
2.1	4.3	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
2.1	6.4	GO:1902490	regulation of sperm capacitation(GO:1902490)
2.1	14.7	GO:0003351	epithelial cilium movement(GO:0003351)
2.1	16.7	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
2.1	16.6	GO:0060736	prostate gland growth(GO:0060736)
2.1	2.1	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
2.1	6.2	GO:0070105	regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.1	37.1	GO:0006853	carnitine shuttle(GO:0006853)
2.1	76.0	GO:0071277	cellular response to calcium ion(GO:0071277)
2.0	6.1	GO:0060004	reflex(GO:0060004)
2.0	6.1	GO:0051102	DNA ligation involved in DNA recombination(GO:0051102)
2.0	4.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
2.0	2.0	GO:0010593	negative regulation of lamellipodium assembly(GO:0010593) negative regulation of lamellipodium organization(GO:1902744)
2.0	2.0	GO:0002221	pattern recognition receptor signaling pathway(GO:0002221) toll-like receptor signaling pathway(GO:0002224)
2.0	10.1	GO:0030500	regulation of bone mineralization(GO:0030500)
2.0	20.0	GO:0035878	nail development(GO:0035878)
2.0	4.0	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
2.0	2.0	GO:0071926	endocannabinoid signaling pathway(GO:0071926)
2.0	8.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
2.0	17.9	GO:0032836	glomerular basement membrane development(GO:0032836)
2.0	12.0	GO:0042426	choline catabolic process(GO:0042426)
2.0	23.8	GO:0007398	ectoderm development(GO:0007398)
2.0	9.9	GO:0060042	retina morphogenesis in camera-type eye(GO:0060042)
2.0	2.0	GO:0060384	innervation(GO:0060384)
2.0	7.9	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
2.0	25.6	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
2.0	2.0	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
2.0	3.9	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
1.9	11.7	GO:2000194	regulation of female gonad development(GO:2000194)
1.9	11.6	GO:0070528	protein kinase C signaling(GO:0070528)
1.9	3.9	GO:0001574	ganglioside biosynthetic process(GO:0001574)
1.9	1.9	GO:0001955	blood vessel maturation(GO:0001955)
1.9	34.6	GO:0060291	long-term synaptic potentiation(GO:0060291)
1.9	3.8	GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
1.9	26.7	GO:0050806	positive regulation of synaptic transmission(GO:0050806)
1.9	3.8	GO:0001935	endothelial cell proliferation(GO:0001935)
1.9	51.4	GO:0030279	negative regulation of ossification(GO:0030279)
1.9	1.9	GO:0003343	proepicardium development(GO:0003342) septum transversum development(GO:0003343)
1.9	11.4	GO:0006768	biotin metabolic process(GO:0006768)
1.9	1.9	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
1.9	28.3	GO:0007130	synaptonemal complex assembly(GO:0007130)
1.9	101.6	GO:0044243	multicellular organism catabolic process(GO:0044243)
1.9	7.5	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.9	11.2	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
1.9	5.6	GO:0001554	luteolysis(GO:0001554)
1.9	1.9	GO:0060972	left/right pattern formation(GO:0060972)
1.9	1.9	GO:2000773	negative regulation of cellular senescence(GO:2000773)
1.9	14.9	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
1.9	7.4	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.8	5.5	GO:0071027	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
1.8	5.5	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
1.8	5.5	GO:0001757	somite specification(GO:0001757)
1.8	38.6	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
1.8	1.8	GO:0071219	cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
1.8	66.0	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
1.8	1.8	GO:0070417	cellular response to cold(GO:0070417)
1.8	9.1	GO:1904779	regulation of protein localization to centrosome(GO:1904779)
1.8	18.3	GO:0048227	plasma membrane to endosome transport(GO:0048227)
1.8	125.2	GO:0007626	locomotory behavior(GO:0007626)
1.8	74.1	GO:0007218	neuropeptide signaling pathway(GO:0007218)
1.8	214.6	GO:0007266	Rho protein signal transduction(GO:0007266)
1.8	1.8	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
1.8	3.6	GO:0035405	histone-threonine phosphorylation(GO:0035405)
1.8	3.6	GO:0019896	axonal transport of mitochondrion(GO:0019896)
1.8	3.6	GO:2000382	positive regulation of mesoderm development(GO:2000382)
1.8	7.1	GO:0042743	hydrogen peroxide metabolic process(GO:0042743)
1.8	1.8	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
1.8	7.1	GO:0070995	NADPH oxidation(GO:0070995)
1.8	28.3	GO:0060323	head morphogenesis(GO:0060323)
1.8	24.7	GO:0007340	acrosome reaction(GO:0007340)
1.8	21.2	GO:0021983	pituitary gland development(GO:0021983)
1.8	21.1	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
1.8	5.3	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
1.7	40.2	GO:1901687	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
1.7	7.0	GO:0032103	positive regulation of response to external stimulus(GO:0032103)
1.7	20.9	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
1.7	10.5	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
1.7	17.4	GO:0032944	regulation of mononuclear cell proliferation(GO:0032944)
1.7	17.4	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
1.7	17.3	GO:0035728	response to hepatocyte growth factor(GO:0035728)
1.7	3.5	GO:0035434	copper ion transmembrane transport(GO:0035434)
1.7	3.4	GO:0001880	Mullerian duct regression(GO:0001880)
1.7	3.4	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
1.7	6.9	GO:0007468	regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
1.7	3.4	GO:0048641	regulation of skeletal muscle tissue development(GO:0048641)
1.7	22.3	GO:0042403	thyroid hormone metabolic process(GO:0042403)
1.7	6.8	GO:2000052	regulation of non-canonical Wnt signaling pathway(GO:2000050) positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
1.7	6.8	GO:0010968	regulation of microtubule nucleation(GO:0010968)
1.7	6.8	GO:0003341	cilium movement(GO:0003341)
1.7	18.6	GO:0016576	histone dephosphorylation(GO:0016576)
1.7	5.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
1.6	3.3	GO:0002024	diet induced thermogenesis(GO:0002024)
1.6	1.6	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
1.6	3.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
1.6	17.8	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
1.6	12.9	GO:0033687	osteoblast proliferation(GO:0033687)
1.6	8.1	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
1.6	6.4	GO:0051026	chiasma assembly(GO:0051026)
1.6	20.9	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.6	22.4	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
1.6	25.5	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
1.6	1.6	GO:0002833	positive regulation of response to biotic stimulus(GO:0002833)
1.6	1.6	GO:0021571	rhombomere 5 development(GO:0021571)
1.6	4.7	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
1.6	4.7	GO:0048536	spleen development(GO:0048536)
1.6	4.7	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
1.6	18.8	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
1.5	9.3	GO:0060051	negative regulation of protein ADP-ribosylation(GO:0010836) negative regulation of protein glycosylation(GO:0060051)
1.5	9.2	GO:0051189	molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
1.5	15.3	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
1.5	1.5	GO:0032494	response to peptidoglycan(GO:0032494)
1.5	18.3	GO:0033622	integrin activation(GO:0033622)
1.5	4.6	GO:0030325	adrenal gland development(GO:0030325)
1.5	10.6	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
1.5	4.5	GO:0071941	nitrogen cycle metabolic process(GO:0071941)
1.5	18.0	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
1.5	3.0	GO:0006622	protein targeting to lysosome(GO:0006622)
1.5	4.5	GO:0006020	inositol metabolic process(GO:0006020)
1.5	4.5	GO:0009304	tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.5	11.9	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.5	1.5	GO:0033564	anterior/posterior axon guidance(GO:0033564)
1.5	5.9	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.5	34.0	GO:0003279	cardiac septum development(GO:0003279)
1.5	2.9	GO:0051597	response to methylmercury(GO:0051597)
1.5	2.9	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002460)
1.5	4.4	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.5	2.9	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
1.5	38.0	GO:0009083	branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
1.5	10.2	GO:0030166	proteoglycan biosynthetic process(GO:0030166)
1.5	4.4	GO:0045919	positive regulation of cytolysis(GO:0045919)
1.5	27.6	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
1.4	7.2	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
1.4	12.9	GO:0045026	plasma membrane fusion(GO:0045026)
1.4	1.4	GO:1903413	cellular response to bile acid(GO:1903413)
1.4	7.0	GO:0006013	mannose metabolic process(GO:0006013)
1.4	1.4	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
1.4	1.4	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
1.4	26.4	GO:0019369	arachidonic acid metabolic process(GO:0019369)
1.4	37.5	GO:0001510	RNA methylation(GO:0001510)
1.4	70.6	GO:0031338	regulation of vesicle fusion(GO:0031338)
1.4	2.8	GO:0008063	Toll signaling pathway(GO:0008063)
1.4	2.7	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
1.3	1.3	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.3	10.8	GO:0031018	endocrine pancreas development(GO:0031018)
1.3	10.7	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.3	1.3	GO:0030259	lipid glycosylation(GO:0030259)
1.3	13.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.3	10.7	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.3	26.6	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
1.3	9.3	GO:0009404	toxin metabolic process(GO:0009404)
1.3	15.9	GO:0032720	negative regulation of tumor necrosis factor production(GO:0032720)
1.3	4.0	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
1.3	1.3	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
1.3	13.1	GO:0034390	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
1.3	5.2	GO:0090200	regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
1.3	1.3	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
1.3	11.7	GO:0048635	negative regulation of muscle organ development(GO:0048635)
1.3	2.6	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.3	3.9	GO:0071351	interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
1.3	15.5	GO:0006516	glycoprotein catabolic process(GO:0006516)
1.3	2.6	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
1.3	3.8	GO:0060700	regulation of ribonuclease activity(GO:0060700)
1.3	11.5	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
1.3	8.9	GO:0040019	positive regulation of embryonic development(GO:0040019)
1.2	10.0	GO:0097576	vacuole fusion(GO:0097576)
1.2	64.8	GO:0006501	C-terminal protein lipidation(GO:0006501)
1.2	6.2	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
1.2	12.4	GO:0050770	regulation of axonogenesis(GO:0050770)
1.2	25.9	GO:0021987	cerebral cortex development(GO:0021987)
1.2	18.4	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
1.2	7.4	GO:0048333	mesodermal cell differentiation(GO:0048333)
1.2	109.6	GO:0070588	calcium ion transmembrane transport(GO:0070588)
1.2	6.1	GO:0046968	peptide antigen transport(GO:0046968)
1.2	6.1	GO:0006102	isocitrate metabolic process(GO:0006102)
1.2	1.2	GO:0006565	L-serine catabolic process(GO:0006565)
1.2	7.2	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.2	3.6	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
1.2	1.2	GO:0001967	suckling behavior(GO:0001967)
1.2	3.6	GO:0001759	organ induction(GO:0001759)
1.2	29.7	GO:0007368	determination of left/right symmetry(GO:0007368)
1.2	9.5	GO:0042723	thiamine-containing compound metabolic process(GO:0042723)
1.2	8.2	GO:0006548	histidine metabolic process(GO:0006547) histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
1.2	5.8	GO:0007617	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
1.2	1.2	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
1.2	3.5	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
1.2	4.6	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
1.2	5.8	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
1.1	4.6	GO:0070627	ferrous iron import(GO:0070627)
1.1	11.5	GO:0031033	myosin filament organization(GO:0031033)
1.1	6.9	GO:0005513	detection of calcium ion(GO:0005513)
1.1	2.3	GO:1904970	brush border assembly(GO:1904970)
1.1	3.4	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
1.1	1.1	GO:0003418	growth plate cartilage chondrocyte differentiation(GO:0003418)
1.1	2.2	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
1.1	4.5	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
1.1	1.1	GO:0033684	regulation of luteinizing hormone secretion(GO:0033684)
1.1	3.3	GO:0044804	nucleophagy(GO:0044804)
1.1	7.8	GO:0061333	renal tubule morphogenesis(GO:0061333)
1.1	2.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
1.1	4.4	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
1.1	2.2	GO:0006701	progesterone biosynthetic process(GO:0006701)
1.1	3.3	GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
1.1	12.0	GO:0010863	positive regulation of phospholipase C activity(GO:0010863)
1.1	26.2	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
1.1	1.1	GO:0030222	eosinophil differentiation(GO:0030222)
1.1	4.3	GO:0006067	ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068)
1.1	3.3	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
1.1	10.8	GO:0036035	osteoclast development(GO:0036035)
1.1	10.7	GO:0070207	protein homotrimerization(GO:0070207)
1.1	3.2	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
1.1	2.1	GO:0006493	protein O-linked glycosylation(GO:0006493)
1.1	1.1	GO:0036342	post-anal tail morphogenesis(GO:0036342)
1.1	2.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.1	7.5	GO:0043691	reverse cholesterol transport(GO:0043691)
1.1	2.1	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
1.1	1.1	GO:2000171	negative regulation of dendrite development(GO:2000171)
1.1	1.1	GO:1902337	mammary gland branching involved in pregnancy(GO:0060745) regulation of apoptotic process involved in morphogenesis(GO:1902337) regulation of apoptotic process involved in development(GO:1904748)
1.0	1.0	GO:0042938	dipeptide transport(GO:0042938)
1.0	2.1	GO:0002088	lens development in camera-type eye(GO:0002088)
1.0	8.3	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
1.0	7.3	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086)
1.0	2.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
1.0	3.1	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
1.0	10.2	GO:0035136	forelimb morphogenesis(GO:0035136)
1.0	6.1	GO:0030252	growth hormone secretion(GO:0030252)
1.0	10.1	GO:0043401	steroid hormone mediated signaling pathway(GO:0043401)
1.0	15.1	GO:0000186	activation of MAPKK activity(GO:0000186)
1.0	4.0	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.0	4.0	GO:0061025	membrane fusion(GO:0061025)
1.0	20.0	GO:0097502	mannosylation(GO:0097502)
1.0	2.0	GO:0034434	steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
1.0	10.9	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.0	4.9	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
1.0	18.7	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
1.0	28.6	GO:0046329	negative regulation of JNK cascade(GO:0046329)
1.0	2.9	GO:0046887	positive regulation of hormone secretion(GO:0046887)
1.0	1.0	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
1.0	5.8	GO:0002759	positive regulation of antimicrobial peptide production(GO:0002225) regulation of antimicrobial humoral response(GO:0002759) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
1.0	107.3	GO:0006469	negative regulation of protein kinase activity(GO:0006469)
1.0	52.0	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
1.0	8.6	GO:0015747	urate transport(GO:0015747)
1.0	11.4	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.9	3.8	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.9	10.3	GO:0030282	bone mineralization(GO:0030282)
0.9	2.8	GO:0097359	UDP-glucosylation(GO:0097359)
0.9	0.9	GO:0010935	regulation of macrophage cytokine production(GO:0010935)
0.9	6.5	GO:0034063	stress granule assembly(GO:0034063)
0.9	6.5	GO:0003073	regulation of systemic arterial blood pressure(GO:0003073)
0.9	16.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.9	23.0	GO:0007565	female pregnancy(GO:0007565)
0.9	10.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.9	9.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.9	12.8	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.9	8.1	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.9	13.5	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.9	1.8	GO:0001573	ganglioside metabolic process(GO:0001573)
0.9	1.8	GO:0046777	protein autophosphorylation(GO:0046777)
0.9	3.5	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.9	4.4	GO:0006824	cobalt ion transport(GO:0006824)
0.9	2.6	GO:0030578	PML body organization(GO:0030578)
0.9	1.7	GO:0001575	globoside metabolic process(GO:0001575)
0.9	17.2	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.9	11.2	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.9	6.0	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.8	4.2	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.8	10.1	GO:0010664	negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.8	3.4	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.8	1.7	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.8	4.2	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.8	0.8	GO:0021670	lateral ventricle development(GO:0021670)
0.8	3.3	GO:0044331	cell-cell adhesion mediated by cadherin(GO:0044331)
0.8	2.5	GO:0034201	response to oleic acid(GO:0034201)
0.8	4.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.8	6.5	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.8	12.9	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.8	0.8	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.8	292.8	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.8	3.2	GO:0010761	fibroblast migration(GO:0010761)
0.8	4.0	GO:0051601	exocyst localization(GO:0051601)
0.8	7.1	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.8	2.3	GO:0003335	corneocyte development(GO:0003335)
0.8	13.9	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.8	9.2	GO:0006706	steroid catabolic process(GO:0006706)
0.8	0.8	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.8	3.8	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.7	0.7	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.7	3.7	GO:0007638	mechanosensory behavior(GO:0007638)
0.7	2.2	GO:0051639	actin filament network formation(GO:0051639)
0.7	2.2	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.7	1.5	GO:0048069	eye pigmentation(GO:0048069)
0.7	8.0	GO:0048747	muscle fiber development(GO:0048747)
0.7	0.7	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.7	3.6	GO:0061668	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.7	5.0	GO:0010543	regulation of platelet activation(GO:0010543)
0.7	4.3	GO:0006972	hyperosmotic response(GO:0006972)
0.7	8.5	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.7	0.7	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.7	15.5	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.7	8.4	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.7	9.0	GO:0043462	regulation of ATPase activity(GO:0043462)
0.7	0.7	GO:0045829	negative regulation of isotype switching(GO:0045829)
0.7	61.7	GO:0030449	regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.7	5.5	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.7	1.4	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.7	1.3	GO:1904528	positive regulation of microtubule binding(GO:1904528)
0.7	2.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.7	4.0	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.7	0.7	GO:0048483	autonomic nervous system development(GO:0048483)
0.7	13.8	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.7	1.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.6	1.9	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.6	2.6	GO:0046348	amino sugar catabolic process(GO:0046348)
0.6	0.6	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.6	2.6	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.6	3.8	GO:0032060	bleb assembly(GO:0032060)
0.6	3.2	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.6	1.3	GO:0045408	regulation of interleukin-6 biosynthetic process(GO:0045408)
0.6	1.2	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.6	1.8	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.6	0.6	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.6	2.4	GO:0007431	salivary gland development(GO:0007431)
0.6	1.8	GO:0036124	histone H3-K9 trimethylation(GO:0036124)
0.6	1.8	GO:0048484	enteric nervous system development(GO:0048484)
0.6	4.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.6	9.2	GO:0045667	regulation of osteoblast differentiation(GO:0045667)
0.6	8.6	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.6	1.1	GO:0009409	response to cold(GO:0009409)
0.6	1.7	GO:0048278	vesicle docking(GO:0048278)
0.6	7.9	GO:0098754	detoxification(GO:0098754)
0.5	3.3	GO:0050909	sensory perception of taste(GO:0050909)
0.5	1.1	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.5	1.1	GO:2000508	regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.5	8.4	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.5	7.3	GO:0001505	regulation of neurotransmitter levels(GO:0001505)
0.5	4.2	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.5	2.6	GO:0042733	embryonic digit morphogenesis(GO:0042733)
0.5	1.0	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.5	0.5	GO:0019249	lactate biosynthetic process(GO:0019249)
0.5	0.5	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.5	1.0	GO:0042551	neuron maturation(GO:0042551)
0.5	2.0	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.5	1.4	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.5	1.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.5	0.5	GO:0060711	labyrinthine layer development(GO:0060711)
0.5	5.0	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.5	1.8	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.4	2.2	GO:0006265	DNA topological change(GO:0006265)
0.4	0.4	GO:0010040	response to iron(II) ion(GO:0010040)
0.4	0.4	GO:1902603	carnitine transmembrane transport(GO:1902603)
0.4	0.4	GO:0002644	negative regulation of tolerance induction(GO:0002644)
0.4	0.9	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.4	2.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.4	0.4	GO:0007635	chemosensory behavior(GO:0007635)
0.4	6.7	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.4	2.1	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.4	3.7	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.4	4.1	GO:0030815	negative regulation of cAMP metabolic process(GO:0030815)
0.4	3.7	GO:0050891	multicellular organismal water homeostasis(GO:0050891)
0.4	2.0	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.4	0.8	GO:0002778	antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.4	2.3	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4	1.5	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4	1.9	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.4	0.8	GO:0098543	detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.4	7.6	GO:0034308	primary alcohol metabolic process(GO:0034308)
0.4	0.4	GO:1903939	regulation of TORC2 signaling(GO:1903939)
0.4	1.4	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.3	2.8	GO:0046330	positive regulation of JNK cascade(GO:0046330)
0.3	1.3	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.3	1.6	GO:0016926	protein desumoylation(GO:0016926)
0.3	1.0	GO:0006835	dicarboxylic acid transport(GO:0006835)
0.3	0.6	GO:0019935	cyclic-nucleotide-mediated signaling(GO:0019935)
0.3	2.2	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.3	0.6	GO:0070932	histone H3 deacetylation(GO:0070932)
0.3	2.2	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.3	3.1	GO:0051480	regulation of cytosolic calcium ion concentration(GO:0051480)
0.3	0.9	GO:0009106	lipoate metabolic process(GO:0009106)
0.3	2.7	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.3	0.3	GO:0071371	cellular response to gonadotropin stimulus(GO:0071371)
0.3	0.3	GO:0035754	B cell chemotaxis(GO:0035754)
0.3	1.1	GO:0008218	bioluminescence(GO:0008218)
0.3	5.9	GO:0046323	glucose import(GO:0046323)
0.3	2.5	GO:0006826	iron ion transport(GO:0006826)
0.3	1.1	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.3	0.6	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.3	6.5	GO:0001706	endoderm formation(GO:0001706)
0.3	0.3	GO:0042116	macrophage activation(GO:0042116)
0.3	1.0	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.3	10.4	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.3	0.3	GO:0051023	regulation of immunoglobulin secretion(GO:0051023)
0.2	1.4	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.2	1.0	GO:0071285	cellular response to lithium ion(GO:0071285)
0.2	0.9	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.2	0.9	GO:0007567	parturition(GO:0007567)
0.2	0.5	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.2	0.2	GO:0070640	vitamin D3 metabolic process(GO:0070640)
0.2	1.1	GO:0001881	receptor recycling(GO:0001881)
0.2	0.9	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501)
0.2	0.9	GO:0072602	interleukin-4 secretion(GO:0072602)
0.2	0.2	GO:0071609	chemokine (C-C motif) ligand 5 production(GO:0071609)
0.2	8.6	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.2	1.3	GO:0071715	icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.2	21.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2	0.2	GO:0007569	cell aging(GO:0007569)
0.2	1.2	GO:0030101	natural killer cell activation(GO:0030101)
0.2	0.8	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.2	1.0	GO:0034501	protein localization to kinetochore(GO:0034501)
0.2	1.0	GO:0021563	glossopharyngeal nerve development(GO:0021563)
0.2	1.0	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.2	3.5	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2	0.2	GO:0007405	neuroblast proliferation(GO:0007405)
0.2	1.1	GO:0009068	aspartate family amino acid catabolic process(GO:0009068)
0.2	0.4	GO:1901654	response to ketone(GO:1901654)
0.2	0.3	GO:1903800	regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	0.3	GO:1904037	positive regulation of epithelial cell apoptotic process(GO:1904037)
0.2	0.3	GO:0048771	tissue remodeling(GO:0048771)
0.2	1.6	GO:0006942	regulation of striated muscle contraction(GO:0006942)
0.2	0.2	GO:0070673	response to interleukin-18(GO:0070673)
0.2	0.2	GO:0048539	bone marrow development(GO:0048539)
0.2	0.6	GO:1901838	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790) regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2	0.6	GO:0072348	sulfur compound transport(GO:0072348)
0.1	0.7	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.1	0.1	GO:2001223	negative regulation of neuron migration(GO:2001223)
0.1	1.9	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.3	GO:1904350	regulation of protein catabolic process in the vacuole(GO:1904350) positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1	0.9	GO:0007000	nucleolus organization(GO:0007000)
0.1	0.1	GO:1903903	regulation of establishment of T cell polarity(GO:1903903)
0.1	0.2	GO:0002347	response to tumor cell(GO:0002347)
0.1	0.2	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1	0.3	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1	0.1	GO:0002076	osteoblast development(GO:0002076)
0.1	0.2	GO:0034311	sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.1	2.4	GO:0007586	digestion(GO:0007586)
0.1	0.2	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1	0.7	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.1	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	0.4	GO:0051552	flavone metabolic process(GO:0051552)
0.1	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.3	GO:0051924	regulation of calcium ion transport(GO:0051924)
0.1	0.5	GO:0018879	biphenyl metabolic process(GO:0018879)
0.1	0.4	GO:0072538	T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539)
0.1	0.6	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.3	GO:0001180	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1	0.3	GO:2000811	negative regulation of anoikis(GO:2000811)
0.1	0.8	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1	0.4	GO:0010762	regulation of fibroblast migration(GO:0010762)
0.1	0.2	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.3	GO:0097178	ruffle assembly(GO:0097178)
0.1	0.3	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.1	2.8	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.2	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.9	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187)
0.0	0.1	GO:0002673	regulation of acute inflammatory response(GO:0002673)
0.0	0.3	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.3	GO:0048706	embryonic skeletal system development(GO:0048706)
0.0	0.1	GO:0042461	photoreceptor cell development(GO:0042461)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
34.5	103.5	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
33.3	133.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
32.3	129.4	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
26.8	26.8	GO:0019034	viral replication complex(GO:0019034)
23.6	70.7	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
21.0	126.2	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
20.9	83.7	GO:0048787	presynaptic active zone membrane(GO:0048787)
19.3	57.9	GO:0060053	neurofilament cytoskeleton(GO:0060053)
19.1	76.4	GO:0070695	FHF complex(GO:0070695)
18.5	222.2	GO:0044327	dendritic spine head(GO:0044327)
17.4	139.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
17.3	69.2	GO:0043293	apoptosome(GO:0043293)
17.2	17.2	GO:0000145	exocyst(GO:0000145)
16.3	81.5	GO:0043194	axon initial segment(GO:0043194)
16.1	32.2	GO:0014802	terminal cisterna(GO:0014802)
15.4	77.1	GO:1990761	growth cone lamellipodium(GO:1990761)
14.9	14.9	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
14.9	44.8	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
14.6	14.6	GO:0016342	catenin complex(GO:0016342)
14.1	98.6	GO:0072487	MSL complex(GO:0072487)
13.5	40.6	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
13.2	52.9	GO:0045160	myosin I complex(GO:0045160)
13.1	248.4	GO:0032591	dendritic spine membrane(GO:0032591)
12.7	50.7	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
12.5	50.2	GO:0030914	STAGA complex(GO:0030914)
12.5	275.5	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
12.4	49.8	GO:0031673	H zone(GO:0031673)
12.3	36.9	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
12.2	48.8	GO:0000333	telomerase catalytic core complex(GO:0000333)
12.1	72.3	GO:0000138	Golgi trans cisterna(GO:0000138)
12.0	131.7	GO:0033391	chromatoid body(GO:0033391)
11.9	71.5	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
11.7	35.0	GO:0005652	nuclear lamina(GO:0005652)
11.7	46.6	GO:0098843	postsynaptic endocytic zone(GO:0098843)
11.6	208.1	GO:0097386	glial cell projection(GO:0097386)
11.5	321.9	GO:0033268	node of Ranvier(GO:0033268)
11.5	34.4	GO:0016938	kinesin I complex(GO:0016938)
11.3	45.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
11.3	56.3	GO:0045298	tubulin complex(GO:0045298)
11.2	56.2	GO:0036128	CatSper complex(GO:0036128)
11.2	44.9	GO:0031302	intrinsic component of endosome membrane(GO:0031302)
11.1	110.8	GO:0071953	elastic fiber(GO:0071953)
11.0	32.9	GO:0097453	mesaxon(GO:0097453) ensheathing process(GO:1990015)
10.8	10.8	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
10.7	138.5	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
10.6	31.8	GO:0044423	virion(GO:0019012) virion part(GO:0044423)
10.5	31.6	GO:0072534	perineuronal net(GO:0072534)
10.5	63.2	GO:0030991	intraciliary transport particle A(GO:0030991)
10.5	52.6	GO:0031256	leading edge membrane(GO:0031256)
10.4	62.4	GO:0005927	muscle tendon junction(GO:0005927)
10.4	166.4	GO:0097512	cardiac myofibril(GO:0097512)
10.3	257.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
10.2	61.3	GO:0033269	internode region of axon(GO:0033269)
10.1	181.8	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
10.0	320.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
9.8	98.0	GO:0097427	microtubule bundle(GO:0097427)
9.8	39.0	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
9.4	131.0	GO:0035102	PRC1 complex(GO:0035102)
9.3	27.8	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
9.2	64.4	GO:0036021	endolysosome lumen(GO:0036021)
9.1	72.6	GO:0098845	postsynaptic endosome(GO:0098845)
9.0	81.4	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
9.0	27.1	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
9.0	116.6	GO:0097418	neurofibrillary tangle(GO:0097418)
8.9	733.0	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
8.9	26.7	GO:0030893	meiotic cohesin complex(GO:0030893)
8.8	70.6	GO:0035253	ciliary rootlet(GO:0035253)
8.8	35.3	GO:0097224	sperm connecting piece(GO:0097224)
8.7	70.0	GO:0044294	dendritic growth cone(GO:0044294)
8.6	69.1	GO:0033270	paranode region of axon(GO:0033270)
8.6	34.5	GO:0005899	insulin receptor complex(GO:0005899)
8.4	33.5	GO:0030485	smooth muscle contractile fiber(GO:0030485)
8.3	16.7	GO:0005883	neurofilament(GO:0005883)
8.3	74.9	GO:0016013	syntrophin complex(GO:0016013)
8.3	33.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
8.2	427.2	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
8.1	24.4	GO:0010370	perinucleolar chromocenter(GO:0010370)
8.1	24.3	GO:0036398	TCR signalosome(GO:0036398)
8.1	48.5	GO:1990130	Iml1 complex(GO:1990130)
8.1	40.3	GO:0000137	Golgi cis cisterna(GO:0000137)
7.9	39.4	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
7.9	7.9	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
7.8	54.6	GO:1903439	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
7.7	46.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
7.7	115.5	GO:0044295	axonal growth cone(GO:0044295)
7.6	15.2	GO:0097059	CNTFR-CLCF1 complex(GO:0097059)
7.5	14.9	GO:0032421	stereocilium(GO:0032420) stereocilium bundle(GO:0032421)
7.4	272.5	GO:0048786	presynaptic active zone(GO:0048786)
7.3	43.7	GO:0097443	sorting endosome(GO:0097443)
7.2	65.0	GO:0043203	axon hillock(GO:0043203)
7.2	21.5	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
7.1	21.4	GO:0071020	post-spliceosomal complex(GO:0071020)
7.0	126.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
7.0	21.0	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
7.0	48.7	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
7.0	278.1	GO:0097546	ciliary base(GO:0097546)
6.8	13.7	GO:0000125	PCAF complex(GO:0000125)
6.8	27.4	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
6.8	6.8	GO:0002139	stereocilia coupling link(GO:0002139)
6.7	20.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
6.5	19.6	GO:0098536	deuterosome(GO:0098536)
6.5	71.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
6.4	19.3	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
6.4	12.8	GO:0033010	paranodal junction(GO:0033010)
6.4	19.2	GO:0097440	apical dendrite(GO:0097440)
6.3	38.0	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
6.3	44.2	GO:0000813	ESCRT I complex(GO:0000813)
6.3	44.1	GO:0060077	inhibitory synapse(GO:0060077)
6.2	93.6	GO:0030877	beta-catenin destruction complex(GO:0030877)
6.2	68.1	GO:0031045	dense core granule(GO:0031045)
6.1	18.3	GO:0044609	DBIRD complex(GO:0044609)
6.1	6.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
6.1	48.4	GO:0005593	FACIT collagen trimer(GO:0005593)
6.0	603.7	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
6.0	17.9	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
5.9	11.8	GO:0035189	Rb-E2F complex(GO:0035189)
5.9	64.4	GO:0002116	semaphorin receptor complex(GO:0002116)
5.8	104.9	GO:0043218	compact myelin(GO:0043218)
5.8	11.5	GO:0044308	axonal spine(GO:0044308)
5.7	22.7	GO:0033596	TSC1-TSC2 complex(GO:0033596)
5.7	67.9	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
5.6	62.0	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
5.6	28.1	GO:0036038	MKS complex(GO:0036038)
5.6	5.6	GO:0043291	RAVE complex(GO:0043291)
5.5	302.3	GO:0042734	presynaptic membrane(GO:0042734)
5.5	21.9	GO:0042583	chromaffin granule(GO:0042583)
5.5	109.0	GO:0032839	dendrite cytoplasm(GO:0032839)
5.4	70.8	GO:0031209	SCAR complex(GO:0031209)
5.4	65.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
5.4	32.5	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
5.4	27.1	GO:0030061	mitochondrial crista(GO:0030061)
5.4	70.2	GO:0043083	synaptic cleft(GO:0043083)
5.4	156.2	GO:0001917	photoreceptor inner segment(GO:0001917)
5.4	37.7	GO:0044300	cerebellar mossy fiber(GO:0044300)
5.3	42.7	GO:0097208	alveolar lamellar body(GO:0097208)
5.3	5.3	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
5.2	20.8	GO:0097165	nuclear stress granule(GO:0097165)
5.2	15.5	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
5.1	303.6	GO:0043195	terminal bouton(GO:0043195)
5.0	450.3	GO:0005604	basement membrane(GO:0005604)
5.0	5.0	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
4.9	14.8	GO:0060187	cell pole(GO:0060187)
4.8	459.3	GO:0043204	perikaryon(GO:0043204)
4.8	19.0	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
4.7	4.7	GO:0032593	insulin-responsive compartment(GO:0032593)
4.6	32.2	GO:0070382	exocytic vesicle(GO:0070382)
4.6	22.8	GO:0034451	centriolar satellite(GO:0034451)
4.5	40.5	GO:0005955	calcineurin complex(GO:0005955)
4.5	45.0	GO:0045180	basal cortex(GO:0045180)
4.5	75.9	GO:0046658	anchored component of plasma membrane(GO:0046658)
4.5	66.8	GO:0031083	BLOC-1 complex(GO:0031083)
4.4	39.9	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
4.3	13.0	GO:0099634	postsynaptic specialization membrane(GO:0099634)
4.3	159.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
4.3	55.9	GO:0030478	actin cap(GO:0030478)
4.3	290.0	GO:0005905	clathrin-coated pit(GO:0005905)
4.2	46.1	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
4.2	8.4	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
4.2	8.3	GO:0034657	GID complex(GO:0034657)
4.2	41.6	GO:0030123	AP-3 adaptor complex(GO:0030123)
4.1	16.6	GO:1990745	EARP complex(GO:1990745)
4.1	844.6	GO:0060076	excitatory synapse(GO:0060076)
4.1	24.7	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
4.1	28.8	GO:0000421	autophagosome membrane(GO:0000421)
4.1	16.4	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
4.1	16.4	GO:0072687	meiotic spindle(GO:0072687)
4.1	24.5	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
4.1	56.8	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
4.0	20.1	GO:1990909	Wnt signalosome(GO:1990909)
4.0	23.9	GO:0016461	unconventional myosin complex(GO:0016461)
4.0	7.9	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
4.0	31.6	GO:0030133	transport vesicle(GO:0030133)
3.9	11.7	GO:0031251	PAN complex(GO:0031251)
3.8	19.1	GO:0070847	core mediator complex(GO:0070847)
3.8	94.6	GO:1902710	GABA receptor complex(GO:1902710)
3.7	44.9	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
3.7	29.6	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
3.7	3.7	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
3.7	32.9	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
3.6	21.8	GO:0032444	activin responsive factor complex(GO:0032444)
3.6	18.1	GO:0097227	sperm annulus(GO:0097227)
3.6	18.1	GO:0005602	complement component C1 complex(GO:0005602)
3.5	173.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
3.5	13.9	GO:0060091	kinocilium(GO:0060091)
3.5	31.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
3.4	27.3	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
3.4	367.9	GO:0098793	presynapse(GO:0098793)
3.4	17.0	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
3.4	10.1	GO:0017119	Golgi transport complex(GO:0017119)
3.4	10.1	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
3.3	16.7	GO:0008275	gamma-tubulin small complex(GO:0008275)
3.3	33.2	GO:0000800	lateral element(GO:0000800)
3.3	314.2	GO:0005814	centriole(GO:0005814)
3.3	144.4	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
3.3	144.4	GO:0036064	ciliary basal body(GO:0036064)
3.3	29.3	GO:0005964	phosphorylase kinase complex(GO:0005964)
3.2	22.5	GO:0001520	outer dense fiber(GO:0001520)
3.1	18.9	GO:1990682	CSF1-CSF1R complex(GO:1990682)
3.1	34.4	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
3.1	12.4	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
3.1	27.8	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
3.1	67.4	GO:0042627	chylomicron(GO:0042627)
3.1	320.7	GO:0005796	Golgi lumen(GO:0005796)
3.0	9.0	GO:0032584	growth cone membrane(GO:0032584)
3.0	48.1	GO:0031527	filopodium membrane(GO:0031527)
3.0	6.0	GO:0071546	pi-body(GO:0071546)
3.0	157.6	GO:0005581	collagen trimer(GO:0005581)
3.0	29.7	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
3.0	53.2	GO:0005922	connexon complex(GO:0005922)
2.9	8.8	GO:1990622	CHOP-ATF3 complex(GO:1990622)
2.9	8.8	GO:0000806	Y chromosome(GO:0000806)
2.9	105.0	GO:0001750	photoreceptor outer segment(GO:0001750)
2.9	14.5	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
2.9	8.7	GO:0014704	intercalated disc(GO:0014704)
2.9	14.4	GO:0097513	myosin II filament(GO:0097513)
2.9	25.7	GO:0008091	spectrin(GO:0008091)
2.9	2.9	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
2.8	48.0	GO:0097225	sperm midpiece(GO:0097225)
2.8	365.6	GO:0055037	recycling endosome(GO:0055037)
2.7	8.1	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
2.7	248.3	GO:0032587	ruffle membrane(GO:0032587)
2.7	21.5	GO:0036157	outer dynein arm(GO:0036157)
2.7	16.0	GO:0005858	axonemal dynein complex(GO:0005858)
2.6	12.9	GO:0005945	6-phosphofructokinase complex(GO:0005945)
2.6	25.6	GO:0042599	lamellar body(GO:0042599)
2.6	551.4	GO:0016323	basolateral plasma membrane(GO:0016323)
2.5	34.9	GO:0043679	axon terminus(GO:0043679)
2.5	17.3	GO:0005827	polar microtubule(GO:0005827)
2.5	29.4	GO:0044232	organelle membrane contact site(GO:0044232)
2.4	19.6	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
2.4	7.2	GO:0019008	molybdopterin synthase complex(GO:0019008)
2.4	113.1	GO:0016324	apical plasma membrane(GO:0016324)
2.4	40.4	GO:0043198	dendritic shaft(GO:0043198)
2.3	16.2	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
2.3	219.9	GO:0030426	growth cone(GO:0030426)
2.3	48.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
2.3	2.3	GO:0030008	TRAPP complex(GO:0030008)
2.3	18.1	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
2.3	11.3	GO:0071148	TEAD-1-YAP complex(GO:0071148)
2.3	469.8	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
2.2	8.9	GO:0097136	Bcl-2 family protein complex(GO:0097136)
2.2	42.1	GO:0016459	myosin complex(GO:0016459)
2.2	6.5	GO:0044447	axoneme part(GO:0044447)
2.1	8.6	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
2.1	35.6	GO:0071141	SMAD protein complex(GO:0071141)
2.1	22.6	GO:0035686	sperm fibrous sheath(GO:0035686)
2.1	6.2	GO:0071437	invadopodium(GO:0071437)
2.0	26.6	GO:0001772	immunological synapse(GO:0001772)
2.0	10.2	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.0	16.0	GO:0034706	sodium channel complex(GO:0034706)
1.9	5.7	GO:0034362	low-density lipoprotein particle(GO:0034362)
1.9	24.6	GO:0000242	pericentriolar material(GO:0000242)
1.8	1.8	GO:0031201	SNARE complex(GO:0031201)
1.8	47.4	GO:0030057	desmosome(GO:0030057)
1.8	10.7	GO:0031985	Golgi cisterna(GO:0031985)
1.8	21.1	GO:0030673	axolemma(GO:0030673)
1.8	19.3	GO:0008385	IkappaB kinase complex(GO:0008385)
1.8	423.6	GO:0045202	synapse(GO:0045202)
1.7	7.0	GO:0031417	NatC complex(GO:0031417)
1.7	297.8	GO:0043025	neuronal cell body(GO:0043025)
1.7	3.5	GO:0032009	early phagosome(GO:0032009)
1.7	6.9	GO:0032311	angiogenin-PRI complex(GO:0032311)
1.7	6.9	GO:0070821	tertiary granule membrane(GO:0070821)
1.7	6.8	GO:0005965	protein farnesyltransferase complex(GO:0005965)
1.6	11.2	GO:0035976	AP1 complex(GO:0035976)
1.6	14.0	GO:0002080	acrosomal membrane(GO:0002080)
1.5	102.3	GO:0030424	axon(GO:0030424)
1.5	84.8	GO:0005791	rough endoplasmic reticulum(GO:0005791)
1.5	13.8	GO:0005579	membrane attack complex(GO:0005579)
1.5	6.1	GO:0002177	manchette(GO:0002177)
1.5	3.0	GO:0043159	acrosomal matrix(GO:0043159)
1.5	23.9	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
1.5	56.6	GO:0016460	myosin II complex(GO:0016460)
1.5	7.4	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
1.5	5.9	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
1.4	62.1	GO:0005801	cis-Golgi network(GO:0005801)
1.4	51.2	GO:0016235	aggresome(GO:0016235)
1.4	20.7	GO:0000974	Prp19 complex(GO:0000974)
1.3	1.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
1.3	79.4	GO:0001726	ruffle(GO:0001726)
1.3	1.3	GO:0036020	endolysosome membrane(GO:0036020)
1.3	2.6	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
1.3	235.7	GO:0043235	receptor complex(GO:0043235)
1.3	117.9	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
1.3	15.2	GO:0043020	NADPH oxidase complex(GO:0043020)
1.2	4155.6	GO:0031224	intrinsic component of membrane(GO:0031224)
1.2	128.2	GO:0005802	trans-Golgi network(GO:0005802)
1.2	13.0	GO:0031089	platelet dense granule lumen(GO:0031089)
1.2	52.2	GO:0008023	transcription elongation factor complex(GO:0008023)
1.1	5.7	GO:0034457	Mpp10 complex(GO:0034457)
1.1	13.4	GO:0005902	microvillus(GO:0005902)
1.1	4.4	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
1.1	4.4	GO:0030896	checkpoint clamp complex(GO:0030896)
1.1	7.5	GO:0030870	Mre11 complex(GO:0030870)
1.0	4.2	GO:0033263	CORVET complex(GO:0033263)
1.0	2.0	GO:0045179	apical cortex(GO:0045179)
1.0	14.3	GO:0016529	sarcoplasmic reticulum(GO:0016529)
1.0	2.0	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
1.0	3.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.0	4.0	GO:0070436	Grb2-EGFR complex(GO:0070436)
1.0	7.0	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
1.0	10.9	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
1.0	7.7	GO:0042587	glycogen granule(GO:0042587)
0.9	16.7	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.9	3.7	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.9	1.8	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.8	5.6	GO:0005869	dynactin complex(GO:0005869)
0.8	44.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.8	7.0	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.8	1.5	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.7	15.5	GO:0035145	exon-exon junction complex(GO:0035145)
0.7	2.2	GO:1990393	3M complex(GO:1990393)
0.7	16.6	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.7	10.0	GO:0031904	endosome lumen(GO:0031904)
0.7	1.4	GO:0042588	zymogen granule(GO:0042588)
0.6	19.7	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.6	91.0	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.6	6.7	GO:0005833	hemoglobin complex(GO:0005833)
0.6	3.9	GO:0042788	polysomal ribosome(GO:0042788)
0.5	11.1	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.4	26.0	GO:0005770	late endosome(GO:0005770)
0.4	1.3	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.4	3.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.4	2.5	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.4	2.0	GO:0097524	sperm plasma membrane(GO:0097524)
0.4	1.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4	0.7	GO:0055087	Ski complex(GO:0055087)
0.3	2.3	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3	1.3	GO:0070876	SOSS complex(GO:0070876)
0.3	1.0	GO:0071749	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.2	0.7	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2	4.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2	2.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.2	0.6	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.2	11.8	GO:0009897	external side of plasma membrane(GO:0009897)
0.2	2.0	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	0.4	GO:0034464	BBSome(GO:0034464)
0.1	0.5	GO:0032449	CBM complex(GO:0032449)
0.1	2.5	GO:0051233	spindle midzone(GO:0051233)
0.1	0.6	GO:0005577	fibrinogen complex(GO:0005577)
0.1	4.7	GO:0005923	bicellular tight junction(GO:0005923)
0.1	104.5	GO:0005615	extracellular space(GO:0005615)
0.1	7.0	GO:0030018	Z disc(GO:0030018)
0.1	0.5	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.6	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.2	GO:0031082	BLOC complex(GO:0031082)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
48.7	146.2	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
44.5	178.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
37.4	149.6	GO:0004356	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
36.0	108.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
34.5	103.5	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
33.4	100.2	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
29.3	87.8	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
27.7	83.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
26.0	182.3	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
24.7	148.1	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
24.2	96.8	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
23.5	94.0	GO:0004803	transposase activity(GO:0004803)
23.4	23.4	GO:0050998	nitric-oxide synthase binding(GO:0050998)
23.3	139.9	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
23.1	69.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
23.0	69.1	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
22.5	134.8	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
21.7	65.1	GO:0070025	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
21.6	86.2	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
21.0	83.9	GO:0035939	microsatellite binding(GO:0035939)
19.6	78.4	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
19.4	38.7	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
18.8	75.3	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
18.8	169.0	GO:0032051	clathrin light chain binding(GO:0032051)
18.0	90.0	GO:0070097	delta-catenin binding(GO:0070097)
18.0	53.9	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
17.7	70.8	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
17.6	70.5	GO:0097001	ceramide binding(GO:0097001)
17.6	52.8	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
17.4	52.2	GO:0032093	SAM domain binding(GO:0032093)
17.4	86.8	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
17.1	68.6	GO:0070051	fibrinogen binding(GO:0070051)
17.1	85.7	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
17.1	68.4	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
16.9	84.3	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
16.8	16.8	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
16.8	168.0	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
16.8	50.4	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
16.5	131.7	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
15.9	79.4	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
15.8	63.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
15.5	62.0	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
15.3	91.8	GO:0015252	hydrogen ion channel activity(GO:0015252)
14.9	14.9	GO:0030226	apolipoprotein receptor activity(GO:0030226)
14.9	44.7	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
14.8	44.4	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
14.8	74.0	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
14.4	43.2	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
14.3	42.8	GO:0004103	choline kinase activity(GO:0004103)
13.8	55.0	GO:0061769	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
13.7	82.4	GO:0043237	laminin-1 binding(GO:0043237)
13.6	81.6	GO:0003998	acylphosphatase activity(GO:0003998)
13.6	40.8	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
13.5	67.5	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
13.5	26.9	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
13.4	26.8	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
13.4	80.2	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
13.3	66.5	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
12.9	25.9	GO:0035033	histone deacetylase regulator activity(GO:0035033)
12.8	64.2	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
12.8	167.0	GO:0046870	cadmium ion binding(GO:0046870)
12.8	154.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
12.8	38.4	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
12.8	12.8	GO:0052812	phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
12.6	37.9	GO:0047325	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
12.6	37.8	GO:0032184	SUMO polymer binding(GO:0032184)
12.5	25.0	GO:0043559	insulin binding(GO:0043559)
12.4	62.1	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
12.3	36.8	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
11.9	47.6	GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
11.7	35.0	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
11.5	161.6	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
11.4	91.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
11.3	79.2	GO:0017002	activin-activated receptor activity(GO:0017002)
11.3	67.8	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
11.3	45.1	GO:0051430	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
11.2	78.6	GO:0031681	G-protein beta-subunit binding(GO:0031681)
11.2	145.2	GO:0005344	oxygen transporter activity(GO:0005344)
11.1	300.8	GO:0050780	dopamine receptor binding(GO:0050780)
11.1	422.8	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
11.1	33.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
11.0	32.9	GO:0052895	norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
10.9	98.4	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
10.9	43.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
10.8	10.8	GO:0005277	acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
10.7	32.1	GO:0034584	piRNA binding(GO:0034584)
10.6	42.6	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
10.6	10.6	GO:0030506	ankyrin binding(GO:0030506)
10.5	52.6	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
10.5	52.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
10.5	31.4	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
10.4	260.8	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
10.3	216.5	GO:0031005	filamin binding(GO:0031005)
10.3	257.1	GO:0004383	guanylate cyclase activity(GO:0004383)
10.3	61.5	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
10.2	51.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
10.2	50.9	GO:0061665	SUMO ligase activity(GO:0061665)
10.2	10.2	GO:0032794	GTPase activating protein binding(GO:0032794)
10.1	10.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
10.1	60.6	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
10.1	40.3	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
10.1	30.2	GO:0030350	iron-responsive element binding(GO:0030350)
10.1	10.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
10.0	50.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
10.0	40.0	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
9.9	59.5	GO:0071837	HMG box domain binding(GO:0071837)
9.8	206.1	GO:0050811	GABA receptor binding(GO:0050811)
9.8	49.0	GO:0034431	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
9.8	39.1	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
9.8	39.0	GO:0047298	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
9.7	29.2	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
9.7	125.9	GO:0097109	neuroligin family protein binding(GO:0097109)
9.6	76.9	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
9.6	9.6	GO:0035276	ethanol binding(GO:0035276)
9.5	19.0	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
9.5	28.5	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
9.4	28.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
9.4	28.1	GO:0004951	cholecystokinin receptor activity(GO:0004951)
9.3	56.0	GO:0016015	morphogen activity(GO:0016015)
9.3	129.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
9.1	73.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
9.1	63.6	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
9.0	54.0	GO:0039552	RIG-I binding(GO:0039552)
8.9	35.6	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
8.9	35.6	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
8.9	35.4	GO:0019770	IgG receptor activity(GO:0019770)
8.8	159.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
8.8	17.6	GO:0052901	polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
8.8	44.0	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
8.8	272.3	GO:0017075	syntaxin-1 binding(GO:0017075)
8.7	8.7	GO:0097677	STAT family protein binding(GO:0097677)
8.6	8.6	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
8.6	25.8	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
8.5	34.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
8.4	92.9	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
8.4	25.2	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
8.2	49.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
8.2	81.7	GO:0022841	potassium ion leak channel activity(GO:0022841)
8.2	32.7	GO:0031716	calcitonin receptor binding(GO:0031716)
8.1	32.5	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
8.1	40.5	GO:0004995	tachykinin receptor activity(GO:0004995)
8.1	56.5	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
8.0	40.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
8.0	40.0	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
8.0	104.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
8.0	48.0	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
8.0	24.0	GO:0070984	SET domain binding(GO:0070984)
8.0	24.0	GO:0070404	NADH binding(GO:0070404)
8.0	47.9	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
8.0	111.4	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
7.8	78.3	GO:0009374	biotin binding(GO:0009374)
7.8	31.3	GO:0004657	proline dehydrogenase activity(GO:0004657)
7.8	155.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
7.8	31.0	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
7.7	7.7	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
7.7	92.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
7.7	46.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
7.7	46.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
7.6	30.4	GO:0005502	11-cis retinal binding(GO:0005502)
7.5	97.8	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
7.4	88.9	GO:1903136	cuprous ion binding(GO:1903136)
7.4	22.2	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
7.4	22.1	GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
7.3	73.4	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
7.3	14.6	GO:0045294	alpha-catenin binding(GO:0045294)
7.3	131.4	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
7.2	50.1	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
7.1	21.4	GO:0035501	MH1 domain binding(GO:0035501)
7.1	21.2	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
7.0	140.9	GO:0043121	neurotrophin binding(GO:0043121)
7.0	42.1	GO:0048495	Roundabout binding(GO:0048495)
6.9	117.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
6.9	34.4	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
6.8	27.4	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
6.8	135.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
6.8	27.1	GO:0042903	tubulin deacetylase activity(GO:0042903)
6.7	33.6	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
6.7	40.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
6.6	106.1	GO:0070411	I-SMAD binding(GO:0070411)
6.6	33.0	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
6.6	85.9	GO:0070700	BMP receptor binding(GO:0070700)
6.6	132.0	GO:0050321	tau-protein kinase activity(GO:0050321)
6.6	39.3	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
6.5	19.5	GO:0061663	NEDD8 ligase activity(GO:0061663)
6.5	71.4	GO:0001042	RNA polymerase I core binding(GO:0001042)
6.5	12.9	GO:0051525	NFAT protein binding(GO:0051525)
6.4	19.3	GO:0003826	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
6.4	50.8	GO:0008131	primary amine oxidase activity(GO:0008131)
6.3	88.7	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
6.3	183.0	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
6.3	31.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
6.2	25.0	GO:0099609	microtubule lateral binding(GO:0099609)
6.2	25.0	GO:0008940	nitrate reductase activity(GO:0008940)
6.2	18.7	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
6.2	55.9	GO:0004969	histamine receptor activity(GO:0004969)
6.2	86.9	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
6.1	30.7	GO:0030552	cAMP binding(GO:0030552)
6.1	30.4	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
6.1	103.4	GO:0015250	water channel activity(GO:0015250)
6.0	283.9	GO:0005158	insulin receptor binding(GO:0005158)
6.0	24.2	GO:0017040	ceramidase activity(GO:0017040)
6.0	198.5	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
6.0	72.0	GO:0008179	adenylate cyclase binding(GO:0008179)
6.0	18.0	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
6.0	18.0	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
6.0	71.7	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
6.0	405.1	GO:0001540	beta-amyloid binding(GO:0001540)
6.0	41.7	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
5.9	35.6	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
5.9	71.2	GO:0019841	retinol binding(GO:0019841)
5.9	70.9	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
5.9	17.6	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
5.9	135.1	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
5.9	88.0	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
5.9	87.9	GO:0005003	ephrin receptor activity(GO:0005003)
5.8	81.6	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
5.8	17.5	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
5.8	17.3	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
5.7	17.2	GO:0001861	complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
5.7	97.6	GO:0019992	diacylglycerol binding(GO:0019992)
5.7	17.0	GO:0004961	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
5.6	33.8	GO:0003777	microtubule motor activity(GO:0003777)
5.6	73.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
5.6	11.2	GO:0005137	interleukin-5 receptor binding(GO:0005137)
5.6	22.5	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
5.6	39.0	GO:0097322	7SK snRNA binding(GO:0097322)
5.6	155.9	GO:0043394	proteoglycan binding(GO:0043394)
5.5	38.8	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
5.5	22.2	GO:0070735	protein-glycine ligase activity(GO:0070735)
5.5	94.0	GO:0070300	phosphatidic acid binding(GO:0070300)
5.5	38.7	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
5.5	60.7	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
5.5	71.6	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
5.5	5.5	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
5.5	5.5	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
5.5	163.8	GO:0017147	Wnt-protein binding(GO:0017147)
5.4	16.3	GO:0019961	interferon binding(GO:0019961)
5.4	130.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
5.4	108.4	GO:0045504	dynein heavy chain binding(GO:0045504)
5.4	86.7	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
5.3	155.0	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
5.3	10.6	GO:0008410	CoA-transferase activity(GO:0008410)
5.3	37.1	GO:0043426	MRF binding(GO:0043426)
5.3	10.6	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
5.3	5.3	GO:0038064	collagen receptor activity(GO:0038064)
5.3	15.8	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
5.2	36.7	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
5.2	20.9	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
5.2	15.7	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
5.2	57.4	GO:0017154	semaphorin receptor activity(GO:0017154)
5.2	15.6	GO:0035473	lipase binding(GO:0035473)
5.2	72.6	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
5.2	15.5	GO:0005174	CD40 receptor binding(GO:0005174)
5.1	30.8	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
5.1	30.8	GO:0042577	lipid phosphatase activity(GO:0042577)
5.1	15.4	GO:0008267	poly-glutamine tract binding(GO:0008267)
5.1	35.9	GO:1990459	transferrin receptor binding(GO:1990459)
5.1	15.3	GO:0010857	calcium-dependent protein kinase activity(GO:0010857)
5.0	70.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
5.0	105.1	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
5.0	9.9	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
5.0	24.8	GO:1904315	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
4.9	34.6	GO:0097642	calcitonin family receptor activity(GO:0097642)
4.9	49.4	GO:0008432	JUN kinase binding(GO:0008432)
4.9	9.9	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
4.9	39.4	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
4.9	24.6	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
4.9	4.9	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
4.9	19.6	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
4.9	19.6	GO:0008431	vitamin E binding(GO:0008431)
4.9	4.9	GO:0032183	SUMO binding(GO:0032183)
4.8	19.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
4.8	43.0	GO:0004985	opioid receptor activity(GO:0004985)
4.8	52.6	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
4.8	28.6	GO:0004305	ethanolamine kinase activity(GO:0004305)
4.7	14.2	GO:0015439	heme-transporting ATPase activity(GO:0015439)
4.7	23.7	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
4.7	9.4	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
4.7	9.4	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
4.7	28.3	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
4.7	112.9	GO:0004890	GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
4.7	4.7	GO:0004924	oncostatin-M receptor activity(GO:0004924)
4.7	14.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
4.7	4.7	GO:0043532	angiostatin binding(GO:0043532)
4.7	79.4	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
4.7	32.7	GO:0050682	AF-2 domain binding(GO:0050682)
4.7	32.6	GO:0004112	cyclic-nucleotide phosphodiesterase activity(GO:0004112)
4.6	83.5	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
4.6	203.9	GO:0030507	spectrin binding(GO:0030507)
4.6	198.7	GO:0017080	sodium channel regulator activity(GO:0017080)
4.6	4.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
4.6	59.7	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
4.6	13.8	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
4.6	9.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
4.6	50.3	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
4.6	18.2	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
4.5	4.5	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
4.5	13.6	GO:0070095	fructose-6-phosphate binding(GO:0070095)
4.5	94.9	GO:0005112	Notch binding(GO:0005112)
4.4	44.5	GO:0017166	vinculin binding(GO:0017166)
4.4	53.1	GO:0045125	bioactive lipid receptor activity(GO:0045125)
4.4	52.9	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
4.4	132.2	GO:0005212	structural constituent of eye lens(GO:0005212)
4.4	30.8	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
4.4	13.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
4.4	52.4	GO:0051011	microtubule minus-end binding(GO:0051011)
4.4	13.1	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
4.4	13.1	GO:0008502	melatonin receptor activity(GO:0008502)
4.4	30.5	GO:0000150	recombinase activity(GO:0000150)
4.3	13.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
4.3	17.3	GO:0008384	IkappaB kinase activity(GO:0008384)
4.3	77.8	GO:0043522	leucine zipper domain binding(GO:0043522)
4.3	17.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
4.3	8.6	GO:0004936	alpha-adrenergic receptor activity(GO:0004936) alpha2-adrenergic receptor activity(GO:0004938)
4.3	12.9	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
4.3	21.5	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056)
4.3	17.1	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
4.3	38.3	GO:0001530	lipopolysaccharide binding(GO:0001530)
4.3	76.5	GO:0043015	gamma-tubulin binding(GO:0043015)
4.2	21.2	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
4.2	63.0	GO:0043560	insulin receptor substrate binding(GO:0043560)
4.2	16.8	GO:0015220	choline transmembrane transporter activity(GO:0015220)
4.2	16.7	GO:0047708	biotinidase activity(GO:0047708)
4.2	12.5	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
4.1	16.6	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
4.1	28.9	GO:0004035	alkaline phosphatase activity(GO:0004035)
4.1	399.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
4.1	140.0	GO:0070412	R-SMAD binding(GO:0070412)
4.1	138.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
4.1	268.5	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
4.0	44.0	GO:0019215	intermediate filament binding(GO:0019215)
4.0	16.0	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
3.9	11.8	GO:0000182	rDNA binding(GO:0000182)
3.9	11.8	GO:0016833	oxo-acid-lyase activity(GO:0016833)
3.9	86.0	GO:0046875	ephrin receptor binding(GO:0046875)
3.9	7.8	GO:0008184	glycogen phosphorylase activity(GO:0008184)
3.9	23.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
3.9	100.9	GO:0031489	myosin V binding(GO:0031489)
3.9	19.4	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
3.9	15.5	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
3.9	15.4	GO:0042030	ATPase inhibitor activity(GO:0042030)
3.9	7.7	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
3.8	30.7	GO:0034235	GPI anchor binding(GO:0034235)
3.8	26.9	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
3.8	26.7	GO:0032036	myosin heavy chain binding(GO:0032036)
3.8	15.2	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
3.8	3.8	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
3.8	34.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
3.8	22.7	GO:0031705	bombesin receptor binding(GO:0031705)
3.7	18.5	GO:0097108	hedgehog family protein binding(GO:0097108)
3.7	74.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
3.7	14.8	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
3.7	40.6	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
3.7	29.4	GO:0004111	creatine kinase activity(GO:0004111)
3.7	22.1	GO:0008430	selenium binding(GO:0008430)
3.7	58.4	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
3.7	32.9	GO:0033691	sialic acid binding(GO:0033691)
3.6	10.9	GO:0047977	hepoxilin-epoxide hydrolase activity(GO:0047977)
3.6	7.3	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
3.6	14.5	GO:0004461	lactose synthase activity(GO:0004461)
3.6	28.9	GO:0008172	S-methyltransferase activity(GO:0008172)
3.6	10.8	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
3.6	39.4	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
3.6	17.9	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
3.6	14.3	GO:0072349	modified amino acid transmembrane transporter activity(GO:0072349)
3.6	117.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
3.6	21.3	GO:0045499	chemorepellent activity(GO:0045499)
3.6	10.7	GO:0004967	glucagon receptor activity(GO:0004967)
3.5	14.2	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
3.5	17.6	GO:0070573	metallodipeptidase activity(GO:0070573)
3.5	10.5	GO:0004828	serine-tRNA ligase activity(GO:0004828)
3.5	20.9	GO:0050816	phosphothreonine binding(GO:0050816)
3.5	10.4	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
3.5	86.9	GO:0004806	triglyceride lipase activity(GO:0004806)
3.4	3.4	GO:0070569	uridylyltransferase activity(GO:0070569)
3.4	13.8	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
3.4	10.3	GO:0030375	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
3.4	40.9	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
3.4	20.4	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
3.4	40.6	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
3.4	10.1	GO:0016426	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
3.4	50.3	GO:0001223	transcription coactivator binding(GO:0001223)
3.3	26.8	GO:0045545	syndecan binding(GO:0045545)
3.3	13.4	GO:0017081	chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869)
3.3	10.0	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
3.3	23.2	GO:0001515	opioid peptide activity(GO:0001515)
3.3	16.5	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
3.3	19.7	GO:0004522	ribonuclease A activity(GO:0004522)
3.3	65.4	GO:0050431	transforming growth factor beta binding(GO:0050431)
3.3	19.6	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
3.3	16.3	GO:0016934	inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
3.3	3.3	GO:0001855	complement component C4b binding(GO:0001855)
3.2	13.0	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
3.2	6.5	GO:0030151	molybdenum ion binding(GO:0030151)
3.2	142.7	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
3.2	13.0	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
3.2	12.9	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
3.2	16.1	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
3.2	41.9	GO:0008140	cAMP response element binding protein binding(GO:0008140)
3.2	15.9	GO:0004994	somatostatin receptor activity(GO:0004994)
3.2	9.5	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
3.2	15.8	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
3.1	15.7	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
3.1	18.8	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
3.1	9.4	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
3.1	65.5	GO:0001948	glycoprotein binding(GO:0001948)
3.1	341.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
3.1	9.3	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
3.1	18.4	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
3.0	27.4	GO:0005243	gap junction channel activity(GO:0005243)
3.0	27.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
3.0	3.0	GO:0043199	sulfate binding(GO:0043199)
3.0	3.0	GO:0042806	fucose binding(GO:0042806)
3.0	18.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
3.0	6.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
3.0	42.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
3.0	8.9	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
3.0	11.8	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
3.0	14.8	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
2.9	8.8	GO:0050501	hyaluronan synthase activity(GO:0050501)
2.9	8.8	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
2.9	5.8	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
2.9	14.4	GO:0008420	CTD phosphatase activity(GO:0008420)
2.9	28.8	GO:0070016	armadillo repeat domain binding(GO:0070016)
2.9	34.4	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
2.9	20.0	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
2.9	2.9	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
2.9	2.9	GO:0004031	aldehyde oxidase activity(GO:0004031)
2.8	56.9	GO:1990939	ATP-dependent microtubule motor activity(GO:1990939)
2.8	31.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
2.8	11.2	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
2.8	151.7	GO:0005262	calcium channel activity(GO:0005262)
2.8	19.5	GO:0015232	heme transporter activity(GO:0015232)
2.8	13.8	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
2.8	63.6	GO:0005521	lamin binding(GO:0005521)
2.8	22.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
2.8	289.6	GO:0003707	steroid hormone receptor activity(GO:0003707)
2.8	27.6	GO:0046790	virion binding(GO:0046790)
2.7	10.9	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
2.7	40.6	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
2.7	16.2	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
2.7	16.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
2.7	216.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
2.7	10.7	GO:0004351	glutamate decarboxylase activity(GO:0004351)
2.7	37.4	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
2.6	36.9	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
2.6	34.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
2.6	18.2	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
2.6	5.1	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
2.6	5.1	GO:0045322	unmethylated CpG binding(GO:0045322)
2.6	7.7	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
2.5	30.6	GO:0004017	adenylate kinase activity(GO:0004017)
2.5	35.7	GO:0004065	arylsulfatase activity(GO:0004065)
2.5	15.2	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
2.5	10.1	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
2.5	42.8	GO:0043014	alpha-tubulin binding(GO:0043014)
2.5	37.2	GO:0048018	receptor agonist activity(GO:0048018)
2.5	12.4	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
2.5	24.6	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
2.5	4.9	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
2.4	9.7	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
2.4	4.9	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.4	9.7	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
2.4	12.1	GO:0004359	glutaminase activity(GO:0004359)
2.4	12.0	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
2.4	28.5	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
2.4	7.1	GO:0042731	PH domain binding(GO:0042731)
2.4	73.6	GO:0008395	steroid hydroxylase activity(GO:0008395)
2.4	2.4	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
2.4	35.4	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
2.4	9.4	GO:0052794	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
2.3	4.7	GO:0004660	protein farnesyltransferase activity(GO:0004660)
2.3	2.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
2.3	11.7	GO:0001594	trace-amine receptor activity(GO:0001594)
2.3	72.2	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
2.3	36.8	GO:0004143	diacylglycerol kinase activity(GO:0004143)
2.3	6.9	GO:0002046	opsin binding(GO:0002046)
2.3	120.7	GO:0019905	syntaxin binding(GO:0019905)
2.3	11.3	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
2.2	4.5	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
2.2	11.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.2	4.5	GO:0019870	potassium channel inhibitor activity(GO:0019870)
2.2	8.9	GO:0050693	LBD domain binding(GO:0050693)
2.2	2.2	GO:0004913	interleukin-4 receptor activity(GO:0004913)
2.2	28.8	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
2.2	17.7	GO:0051018	protein kinase A binding(GO:0051018)
2.2	219.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
2.2	72.9	GO:0001784	phosphotyrosine binding(GO:0001784)
2.2	6.6	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
2.2	6.6	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
2.2	6.6	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
2.2	15.3	GO:0016594	glycine binding(GO:0016594)
2.2	45.5	GO:0003785	actin monomer binding(GO:0003785)
2.2	2.2	GO:0034056	estrogen response element binding(GO:0034056)
2.2	10.8	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
2.2	12.9	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
2.1	17.2	GO:0030172	troponin C binding(GO:0030172)
2.1	12.8	GO:0004614	phosphoglucomutase activity(GO:0004614)
2.1	2.1	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.1	23.3	GO:0045159	myosin II binding(GO:0045159)
2.1	8.5	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701) MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
2.1	31.7	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
2.1	8.3	GO:0015057	thrombin receptor activity(GO:0015057)
2.1	10.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.0	47.1	GO:0045502	dynein binding(GO:0045502)
2.0	26.5	GO:0005272	sodium channel activity(GO:0005272)
2.0	2.0	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
2.0	18.1	GO:0050700	CARD domain binding(GO:0050700)
2.0	12.0	GO:0004859	phospholipase inhibitor activity(GO:0004859)
2.0	22.0	GO:0003996	acyl-CoA ligase activity(GO:0003996)
2.0	2.0	GO:1990239	steroid hormone binding(GO:1990239)
2.0	12.0	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
2.0	33.8	GO:0071889	14-3-3 protein binding(GO:0071889)
2.0	4.0	GO:0001968	fibronectin binding(GO:0001968)
2.0	61.3	GO:0008146	sulfotransferase activity(GO:0008146)
2.0	19.6	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
2.0	88.3	GO:0042162	telomeric DNA binding(GO:0042162)
2.0	2.0	GO:0008253	5'-nucleotidase activity(GO:0008253)
2.0	21.5	GO:0097016	L27 domain binding(GO:0097016)
1.9	1.9	GO:0050613	delta14-sterol reductase activity(GO:0050613)
1.9	35.0	GO:0022839	calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)
1.9	15.6	GO:0032027	myosin light chain binding(GO:0032027)
1.9	3.9	GO:0070325	lipoprotein particle receptor binding(GO:0070325)
1.9	1.9	GO:0035497	cAMP response element binding(GO:0035497)
1.9	9.5	GO:0005499	vitamin D binding(GO:0005499)
1.9	9.4	GO:0004925	prolactin receptor activity(GO:0004925)
1.9	11.3	GO:0034711	inhibin binding(GO:0034711)
1.9	11.2	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
1.8	5.5	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
1.8	225.9	GO:0017137	Rab GTPase binding(GO:0017137)
1.8	5.5	GO:0005165	neurotrophin receptor binding(GO:0005165)
1.8	3.6	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
1.8	5.5	GO:0031685	adenosine receptor binding(GO:0031685)
1.8	28.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
1.8	23.4	GO:0043295	glutathione binding(GO:0043295)
1.8	3.6	GO:0070052	collagen V binding(GO:0070052)
1.8	354.4	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
1.8	19.4	GO:0008066	glutamate receptor activity(GO:0008066)
1.7	7.0	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
1.7	3.5	GO:0016019	peptidoglycan receptor activity(GO:0016019)
1.7	3.5	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
1.7	34.3	GO:0005109	frizzled binding(GO:0005109)
1.7	162.8	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
1.6	16.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
1.6	24.3	GO:0008417	fucosyltransferase activity(GO:0008417)
1.6	4.9	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
1.6	6.5	GO:0016499	orexin receptor activity(GO:0016499)
1.6	17.6	GO:0015368	calcium:cation antiporter activity(GO:0015368)
1.6	4.8	GO:0042954	lipoprotein transporter activity(GO:0042954)
1.6	3.2	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.6	23.8	GO:0009881	photoreceptor activity(GO:0009881)
1.6	7.9	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
1.6	11.0	GO:0051787	misfolded protein binding(GO:0051787)
1.6	20.3	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) TFIIB-class transcription factor binding(GO:0001093)
1.6	3.1	GO:0098770	FBXO family protein binding(GO:0098770)
1.6	3.1	GO:0070888	E-box binding(GO:0070888)
1.5	13.9	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
1.5	1.5	GO:0004935	adrenergic receptor activity(GO:0004935)
1.5	4.6	GO:0001596	angiotensin type I receptor activity(GO:0001596)
1.5	7.6	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
1.5	4.5	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
1.5	60.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
1.5	33.9	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
1.5	4.4	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.5	10.3	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
1.5	111.5	GO:0004860	protein kinase inhibitor activity(GO:0004860)
1.5	276.0	GO:0005096	GTPase activator activity(GO:0005096)
1.4	43.3	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
1.4	20.0	GO:0016805	dipeptidase activity(GO:0016805)
1.4	11.4	GO:0004957	prostaglandin E receptor activity(GO:0004957)
1.4	5.5	GO:0030274	LIM domain binding(GO:0030274)
1.4	4.1	GO:0046997	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
1.4	63.8	GO:0044325	ion channel binding(GO:0044325)
1.3	1.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
1.3	1.3	GO:0098847	sequence-specific single stranded DNA binding(GO:0098847)
1.3	215.1	GO:0008017	microtubule binding(GO:0008017)
1.3	2.6	GO:0031893	vasopressin receptor binding(GO:0031893)
1.3	4.0	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.3	13.0	GO:0052742	phosphatidylinositol kinase activity(GO:0052742)
1.3	3.9	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
1.3	6.4	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
1.3	13.8	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.3	65.2	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
1.2	8.7	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.2	8.7	GO:0070891	lipoteichoic acid binding(GO:0070891)
1.2	29.8	GO:0005184	neuropeptide hormone activity(GO:0005184)
1.2	320.0	GO:0004930	G-protein coupled receptor activity(GO:0004930)
1.2	9.8	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
1.2	8.5	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
1.2	14.6	GO:0000149	SNARE binding(GO:0000149)
1.2	9.7	GO:1990405	protein antigen binding(GO:1990405)
1.2	6.0	GO:0036122	BMP binding(GO:0036122)
1.2	1.2	GO:0032142	single guanine insertion binding(GO:0032142)
1.2	2.3	GO:0042289	MHC class II protein binding(GO:0042289)
1.2	5.8	GO:1901567	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
1.2	3.5	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.1	11.4	GO:0042809	vitamin D receptor binding(GO:0042809)
1.1	35.1	GO:0005044	scavenger receptor activity(GO:0005044)
1.1	2.2	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.1	11.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
1.1	55.7	GO:0048306	calcium-dependent protein binding(GO:0048306)
1.1	7.8	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
1.1	3.3	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.1	3.2	GO:0004645	phosphorylase activity(GO:0004645)
1.1	4.3	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
1.1	2.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
1.0	53.3	GO:0008080	N-acetyltransferase activity(GO:0008080)
1.0	2.0	GO:0004797	thymidine kinase activity(GO:0004797)
1.0	5.9	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
1.0	15.8	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
1.0	8.8	GO:0050840	extracellular matrix binding(GO:0050840)
1.0	18.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
1.0	11.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
1.0	4.9	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.0	2.9	GO:0016841	ammonia-lyase activity(GO:0016841)
1.0	274.4	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.9	21.8	GO:0015276	ligand-gated ion channel activity(GO:0015276) ligand-gated channel activity(GO:0022834)
0.9	13.2	GO:0005518	collagen binding(GO:0005518)
0.9	2.8	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.9	17.7	GO:0005484	SNAP receptor activity(GO:0005484)
0.9	2.8	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.9	3.7	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.9	11.0	GO:0038191	neuropilin binding(GO:0038191)
0.9	7.2	GO:0032451	demethylase activity(GO:0032451)
0.9	1.8	GO:0005151	interleukin-1, Type II receptor binding(GO:0005151)
0.9	30.6	GO:0008374	O-acyltransferase activity(GO:0008374)
0.9	3.6	GO:0035325	Toll-like receptor binding(GO:0035325)
0.9	1.8	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.9	12.5	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.9	29.4	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.9	2.7	GO:0070728	leucine binding(GO:0070728)
0.9	5.3	GO:0045569	TRAIL binding(GO:0045569)
0.9	7.9	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.9	4.4	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.9	432.3	GO:0005509	calcium ion binding(GO:0005509)
0.9	12.1	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.9	8.6	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.8	5.0	GO:0003696	satellite DNA binding(GO:0003696)
0.8	1.7	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.8	6.6	GO:0030275	LRR domain binding(GO:0030275)
0.8	51.6	GO:0005179	hormone activity(GO:0005179)
0.8	5.6	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.8	11.1	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.8	9.4	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.8	4.7	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.8	151.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.8	0.8	GO:0016004	phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.8	0.8	GO:0048185	activin binding(GO:0048185)
0.7	3.7	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7	2.2	GO:0003916	DNA topoisomerase activity(GO:0003916)
0.7	4.4	GO:0031419	cobalamin binding(GO:0031419)
0.7	34.0	GO:0008013	beta-catenin binding(GO:0008013)
0.7	1.4	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.7	5.7	GO:0070330	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.7	6.4	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.7	15.6	GO:0051393	alpha-actinin binding(GO:0051393)
0.7	10.5	GO:0070566	adenylyltransferase activity(GO:0070566)
0.7	9.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.7	5.5	GO:0004565	beta-galactosidase activity(GO:0004565)
0.7	4.8	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.7	4.8	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.7	2.0	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.7	1.3	GO:0031013	troponin I binding(GO:0031013)
0.7	2.7	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.6	3.2	GO:0003796	lysozyme activity(GO:0003796)
0.6	2.6	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.6	2.6	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.6	35.7	GO:0035064	methylated histone binding(GO:0035064)
0.6	2.5	GO:0008158	hedgehog receptor activity(GO:0008158)
0.6	2.4	GO:0042020	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.6	0.6	GO:0015295	solute:proton symporter activity(GO:0015295)
0.6	0.6	GO:0001007	transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.6	1.7	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.6	3.5	GO:0003774	motor activity(GO:0003774)
0.6	3.4	GO:0005254	chloride channel activity(GO:0005254)
0.6	3.4	GO:0042805	actinin binding(GO:0042805)
0.6	474.2	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.5	4.4	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.5	7.1	GO:0042056	chemoattractant activity(GO:0042056)
0.5	1.1	GO:0032135	DNA insertion or deletion binding(GO:0032135) single base insertion or deletion binding(GO:0032138)
0.5	4.2	GO:0015459	potassium channel regulator activity(GO:0015459)
0.5	2.6	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.5	4.1	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.5	3.1	GO:0048039	ubiquinone binding(GO:0048039)
0.5	2.0	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.5	1.5	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.5	13.1	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.5	3.3	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.5	31.6	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.5	5.5	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.4	0.9	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.4	11.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.4	8.4	GO:0017022	myosin binding(GO:0017022)
0.4	1.7	GO:0030492	hemoglobin binding(GO:0030492)
0.4	2.5	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4	2.5	GO:0035198	miRNA binding(GO:0035198)
0.4	2.3	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.4	10.0	GO:0008009	chemokine activity(GO:0008009)
0.4	3.7	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.3	0.3	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.3	1.7	GO:0015643	toxic substance binding(GO:0015643)
0.3	1.7	GO:0039706	co-receptor binding(GO:0039706)
0.3	1.4	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3	2.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.3	1.0	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.3	0.9	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3	4.6	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.3	0.9	GO:0070283	lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.3	1.2	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.3	1.4	GO:0000828	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3	1.1	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.3	1.9	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3	1.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.3	1.0	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3	0.3	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.3	3.3	GO:0032395	MHC class II receptor activity(GO:0032395)
0.2	14.2	GO:0005516	calmodulin binding(GO:0005516)
0.2	1.9	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.2	0.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.2	3.1	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.2	0.8	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.2	2.7	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2	0.6	GO:0071209	U7 snRNA binding(GO:0071209)
0.2	0.4	GO:0004000	adenosine deaminase activity(GO:0004000)
0.2	0.4	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2	0.9	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.2	3.7	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2	0.6	GO:0042015	interleukin-20 binding(GO:0042015)
0.2	1.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.5	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	1.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	7.9	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.1	1.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	1.7	GO:0004497	monooxygenase activity(GO:0004497)
0.1	2.7	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1	0.5	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.7	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	0.5	GO:0030553	cGMP binding(GO:0030553)
0.1	0.9	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.8	GO:0032396	inhibitory MHC class I receptor activity(GO:0032396)
0.1	0.3	GO:0016405	CoA-ligase activity(GO:0016405)
0.1	0.4	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.3	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
0.1	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.5	GO:0019864	IgG binding(GO:0019864)
0.0	0.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.2	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0	0.1	GO:0017129	triglyceride binding(GO:0017129)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.0	GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
22.4	22.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
18.6	37.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
16.5	33.0	PID IFNG PATHWAY	IFN-gamma pathway
12.8	460.4	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
12.6	50.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
8.8	17.6	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
8.5	85.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
8.3	83.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
8.2	24.7	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
7.6	189.9	PID LPA4 PATHWAY	LPA4-mediated signaling events
7.6	334.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
6.7	287.6	PID S1P S1P3 PATHWAY	S1P3 pathway
6.2	172.7	ST GAQ PATHWAY	G alpha q Pathway
6.0	282.7	PID RAS PATHWAY	Regulation of Ras family activation
5.7	268.7	NABA COLLAGENS	Genes encoding collagen proteins
5.5	5.5	PID S1P S1P2 PATHWAY	S1P2 pathway
5.3	210.7	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
5.2	146.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
5.2	348.1	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
4.8	72.6	PID EPHA FWDPATHWAY	EPHA forward signaling
4.7	118.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
4.6	23.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
4.6	73.9	PID ALK2 PATHWAY	ALK2 signaling events
4.5	22.7	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
4.5	72.1	ST G ALPHA S PATHWAY	G alpha s Pathway
4.2	105.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
4.1	8.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
4.0	12.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
4.0	7.9	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
4.0	51.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
3.9	282.0	PID FGF PATHWAY	FGF signaling pathway
3.8	184.8	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
3.6	69.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
3.6	183.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
3.6	32.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
3.4	769.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
3.4	34.0	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
3.3	146.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
3.2	102.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
3.1	6.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
3.1	125.3	ST JNK MAPK PATHWAY	JNK MAPK Pathway
3.1	27.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
2.9	20.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
2.9	117.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
2.8	96.5	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
2.8	13.9	ST STAT3 PATHWAY	STAT3 Pathway
2.8	121.9	PID SHP2 PATHWAY	SHP2 signaling
2.8	44.2	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
2.7	21.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
2.6	115.6	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
2.5	43.1	ST G ALPHA I PATHWAY	G alpha i Pathway
2.5	296.9	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
2.5	32.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
2.4	58.7	PID REELIN PATHWAY	Reelin signaling pathway
2.4	29.1	ST GA13 PATHWAY	G alpha 13 Pathway
2.4	585.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
2.4	51.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
2.3	93.6	PID ARF6 PATHWAY	Arf6 signaling events
2.3	160.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
2.2	42.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
2.2	26.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
2.1	25.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
2.1	151.0	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
2.0	54.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
2.0	2.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
1.9	11.7	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
1.9	40.3	PID INSULIN PATHWAY	Insulin Pathway
1.9	631.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
1.9	37.7	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
1.9	41.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
1.8	7.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
1.7	43.2	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
1.5	15.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
1.5	29.0	PID ENDOTHELIN PATHWAY	Endothelins
1.5	10.6	PID NECTIN PATHWAY	Nectin adhesion pathway
1.5	241.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.5	9.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
1.5	8.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
1.4	50.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
1.4	17.9	PID RAC1 PATHWAY	RAC1 signaling pathway
1.3	15.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
1.3	16.9	PID CDC42 PATHWAY	CDC42 signaling events
1.3	69.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
1.3	38.0	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
1.2	8.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
1.2	25.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
1.2	13.9	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
1.1	12.0	PID NOTCH PATHWAY	Notch signaling pathway
1.1	34.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
1.0	25.9	PID IL12 2PATHWAY	IL12-mediated signaling events
1.0	25.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
1.0	20.4	PID IL1 PATHWAY	IL1-mediated signaling events
1.0	16.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.9	15.0	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.8	5.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.8	22.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.8	26.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.7	24.6	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.7	4.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.6	17.6	PID MTOR 4PATHWAY	mTOR signaling pathway
0.6	2.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6	3.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.6	5.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.5	6.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.5	0.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.5	6.9	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.5	17.2	PID AURORA A PATHWAY	Aurora A signaling
0.5	0.9	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.4	28.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.3	2.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3	5.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	0.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	0.5	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.1	0.5	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.1	1.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
26.1	26.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
22.9	45.9	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
20.4	20.4	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
18.9	340.4	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
13.0	38.9	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
12.8	357.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
12.5	149.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
11.5	11.5	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
11.3	202.8	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
11.2	78.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
11.1	99.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
10.9	10.9	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
10.8	54.1	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
10.7	256.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
10.5	569.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
10.4	354.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
9.7	29.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
9.5	66.8	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
8.8	8.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
8.7	52.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
8.7	182.9	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
8.6	17.2	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
8.3	16.7	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
7.4	44.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
7.3	87.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
7.3	94.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
7.1	114.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
7.1	149.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
6.9	103.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
6.8	252.9	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
6.8	176.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
6.7	128.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
6.7	254.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
6.7	207.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
6.6	417.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
6.4	102.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
6.4	275.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
6.3	12.6	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
6.2	43.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
6.1	30.3	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
5.9	100.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
5.8	116.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
5.8	139.5	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
5.7	135.8	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
5.4	32.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
5.2	10.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
5.1	128.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
5.1	280.2	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
5.0	34.8	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
4.9	68.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
4.9	121.5	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
4.8	19.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
4.8	33.5	REACTOME SIGNALING BY GPCR	Genes involved in Signaling by GPCR
4.7	220.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
4.6	64.7	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
4.6	4.6	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
4.6	114.7	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
4.5	86.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
4.4	71.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
4.4	92.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
4.4	87.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
4.3	59.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
4.2	8.5	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
4.2	4.2	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
4.1	175.1	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
3.9	27.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
3.9	752.1	REACTOME NEURONAL SYSTEM	Genes involved in Neuronal System
3.8	65.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
3.7	63.1	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
3.7	18.5	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
3.6	43.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
3.5	13.9	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
3.4	27.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
3.4	73.9	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
3.3	33.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
3.3	9.9	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
3.3	68.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
3.1	40.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
3.0	20.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
3.0	100.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
2.9	270.9	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
2.9	210.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
2.7	68.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
2.7	54.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
2.7	32.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
2.7	74.5	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
2.6	28.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
2.5	35.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
2.5	79.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
2.5	86.2	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
2.5	95.7	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
2.3	16.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
2.2	65.2	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
2.2	9.0	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
2.2	42.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
2.2	8.8	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
2.1	25.8	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
2.1	83.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
2.1	112.6	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
2.1	181.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
2.0	157.4	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
2.0	28.3	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
2.0	64.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
2.0	40.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
2.0	329.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
2.0	19.8	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
2.0	67.0	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
2.0	15.7	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
1.9	62.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.9	92.7	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
1.9	1.9	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
1.9	22.6	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
1.8	3.6	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
1.8	30.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
1.8	8.9	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
1.7	5.2	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
1.7	13.7	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
1.7	69.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
1.7	42.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
1.6	25.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.5	21.4	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
1.5	115.6	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
1.5	30.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
1.4	41.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
1.4	24.9	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
1.4	17.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
1.3	2.7	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
1.3	14.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
1.3	11.8	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
1.3	12.9	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
1.2	19.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
1.2	21.3	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
1.2	15.1	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
1.1	29.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
1.0	3.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
1.0	20.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
1.0	1.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
1.0	22.0	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.9	23.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.9	44.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.8	8.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.8	7.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.8	14.8	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.8	8.4	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.7	11.1	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.7	7.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.7	19.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.7	0.7	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.6	5.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.6	5.7	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.6	8.9	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.6	8.9	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.6	3.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.6	20.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.5	1.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.5	7.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.5	1.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.5	125.6	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.4	3.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.4	18.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.4	7.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	6.7	REACTOME GPCR LIGAND BINDING	Genes involved in GPCR ligand binding
0.3	0.3	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.3	11.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	7.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.2	0.7	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.2	4.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.4	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	2.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	2.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	1.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	1.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.8	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.1	0.1	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
0.0	2.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.4	REACTOME DEFENSINS	Genes involved in Defensins

Results for WT1_MTF1_ZBTB7B

Z-value: 4.15

Motif logo

Transcription factors associated with WT1_MTF1_ZBTB7B

Activity-expression correlation:

Activity profile of WT1_MTF1_ZBTB7B motif

Sorted Z-values of WT1_MTF1_ZBTB7B motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of WT1_MTF1_ZBTB7B

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: