averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)



Z-value: 8.82

Motif logo

Transcription factors associated with YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

Gene Symbol Gene ID Gene Info
ENSG00000065978.13 Y-box binding protein 1
ENSG00000170345.5 Fos proto-oncogene, AP-1 transcription factor subunit
ENSG00000066136.15 nuclear transcription factor Y subunit gamma
ENSG00000001167.10 nuclear transcription factor Y subunit alpha
ENSG00000120837.3 nuclear transcription factor Y subunit beta
ENSG00000115816.9 CCAAT enhancer binding protein zeta

Activity-expression correlation:

Activity profile of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif

Sorted Z-values of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_154947148 329.21 ENST00000368436.1
CDC28 protein kinase regulatory subunit 1B
chr1_+_154947126 313.29 ENST00000368439.1
CDC28 protein kinase regulatory subunit 1B
chr17_-_38574169 289.03 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr14_+_54863739 287.52 ENST00000541304.1
cyclin-dependent kinase inhibitor 3
chr14_+_54863667 279.35 ENST00000335183.6
cyclin-dependent kinase inhibitor 3
chr14_+_54863682 269.87 ENST00000543789.2
cyclin-dependent kinase inhibitor 3
chr1_-_197115818 252.56 ENST00000367409.4
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr4_-_174255536 244.96 ENST00000446922.2
high mobility group box 2
chr9_+_91926103 243.06 ENST00000314355.6
CDC28 protein kinase regulatory subunit 2
chr3_+_172468505 218.39 ENST00000427830.1
epithelial cell transforming sequence 2 oncogene
chr1_-_153643442 209.73 ENST00000368681.1
interleukin enhancer binding factor 2
chr3_+_172468472 201.12 ENST00000232458.5
epithelial cell transforming sequence 2 oncogene
chr17_+_26646175 197.63 ENST00000583381.1
transmembrane protein 97
chr19_-_55919087 189.78 ENST00000587845.1
ubiquitin-conjugating enzyme E2S
chr2_-_61765315 169.78 ENST00000406957.1
exportin 1 (CRM1 homolog, yeast)
chr17_-_8113886 164.90 ENST00000577833.1
aurora kinase B
chr10_+_124914285 162.69 ENST00000407911.2
BUB3 mitotic checkpoint protein
chr5_+_151151471 160.78 ENST00000394123.3
GTPase activating protein (SH3 domain) binding protein 1
chr5_+_137514834 159.24 ENST00000508792.1
kinesin family member 20A
chr5_+_177631523 158.60 ENST00000506339.1
heterogeneous nuclear ribonucleoprotein A/B
chr20_+_44441271 155.85 ENST00000335046.3
ubiquitin-conjugating enzyme E2C
chr5_+_151151504 155.37 ENST00000356245.3
GTPase activating protein (SH3 domain) binding protein 1
chr14_-_21737551 154.73 ENST00000554891.1
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr15_+_59397275 153.42 ENST00000288207.2
cyclin B2
chr20_+_47662805 151.59 ENST00000262982.2
CSE1 chromosome segregation 1-like (yeast)
chr15_-_64673630 151.23 ENST00000558008.1
chr10_+_62538089 150.83 ENST00000519078.2
cyclin-dependent kinase 1
chr5_+_177631497 149.44 ENST00000358344.3
heterogeneous nuclear ribonucleoprotein A/B
chr17_-_8113542 148.71 ENST00000578549.1
aurora kinase B
chr11_+_63953691 148.59 ENST00000543847.1
stress-induced-phosphoprotein 1
chr2_+_10262442 148.24 ENST00000360566.2
ribonucleotide reductase M2
chr1_+_43824577 148.21 ENST00000310955.6
cell division cycle 20
chr1_+_43824669 146.76 ENST00000372462.1
cell division cycle 20
chr5_+_137514687 145.03 ENST00000394894.3
kinesin family member 20A
chr15_+_59397298 143.71 ENST00000559622.1
cyclin B2
chr14_-_21737610 143.65 ENST00000320084.7
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chrX_+_154444643 142.23 ENST00000286428.5
von Hippel-Lindau binding protein 1
chr17_+_26646121 142.19 ENST00000226230.6
transmembrane protein 97
chr4_-_174256276 137.28 ENST00000296503.5
high mobility group box 2
chr12_+_104324112 135.19 ENST00000299767.5
heat shock protein 90kDa beta (Grp94), member 1
chr1_+_62902308 135.11 ENST00000339950.4
ubiquitin specific peptidase 1
chr20_+_44441626 134.26 ENST00000372568.4
ubiquitin-conjugating enzyme E2C
chr20_+_44441304 132.30 ENST00000352551.5
ubiquitin-conjugating enzyme E2C
chr1_+_110881945 131.87 ENST00000602849.1
RNA binding motif protein 15
chr20_-_5100591 131.63 ENST00000379143.5
proliferating cell nuclear antigen
chr10_+_62538248 131.55 ENST00000448257.2
cyclin-dependent kinase 1
chr17_-_76183111 130.84 ENST00000405273.1
thymidine kinase 1, soluble
chr12_+_56211703 128.47 ENST00000243045.5
ORM1-like 2 (S. cerevisiae)
chr20_+_44441215 128.08 ENST00000356455.4
ubiquitin-conjugating enzyme E2C
chr1_+_62901968 126.84 ENST00000452143.1
ubiquitin specific peptidase 1
chr5_+_159848807 125.26 ENST00000352433.5
pituitary tumor-transforming 1
chr5_+_68462837 121.18 ENST00000256442.5
cyclin B1
chr3_+_179280668 120.89 ENST00000429709.2
actin-like 6A
chr5_+_145826867 120.61 ENST00000296702.5
transcription elongation regulator 1
chr2_+_10262857 119.99 ENST00000304567.5
ribonucleotide reductase M2
chr1_+_38158090 116.67 ENST00000373055.1
cell division cycle associated 8
chr1_-_150669500 114.22 ENST00000271732.3
golgi phosphoprotein 3-like
chr5_+_68462944 113.95 ENST00000506572.1
cyclin B1
chr5_+_162864575 111.30 ENST00000512163.1
cyclin G1
chr19_+_50180317 111.28 ENST00000534465.1
protein arginine methyltransferase 1
chr15_+_41624892 109.30 ENST00000260359.6
nucleolar and spindle associated protein 1
chr5_+_68463043 107.74 ENST00000508407.1
cyclin B1
chr20_-_48770174 106.90 ENST00000341698.2
TMEM189-UBE2V1 readthrough
chr4_-_1713977 105.89 ENST00000318386.4
stem-loop binding protein
chr7_+_73097890 104.58 ENST00000265758.2
Williams Beuren syndrome chromosome region 22
chr20_-_48770244 102.77 ENST00000371650.5
transmembrane protein 189
chr7_-_99699538 100.90 ENST00000343023.6
minichromosome maintenance complex component 7
chr5_+_74633036 100.35 ENST00000343975.5
3-hydroxy-3-methylglutaryl-CoA reductase
chr11_+_63953587 100.27 ENST00000305218.4
stress-induced-phosphoprotein 1
chr17_+_6347729 99.76 ENST00000572447.1
family with sequence similarity 64, member A
chr14_+_58711539 99.11 ENST00000216455.4
proteasome (prosome, macropain) subunit, alpha type, 3
chr10_+_124913930 98.58 ENST00000368858.5
BUB3 mitotic checkpoint protein
chr1_+_41174988 98.38 ENST00000372652.1
nuclear transcription factor Y, gamma
chr8_+_11660227 98.25 ENST00000443614.2
farnesyl-diphosphate farnesyltransferase 1
chr6_+_24775153 98.22 ENST00000356509.3
geminin, DNA replication inhibitor
chr2_+_27008865 98.17 ENST00000335756.4
centromere protein A
chr17_+_6347761 96.97 ENST00000250056.8
family with sequence similarity 64, member A
chr2_-_96874553 96.72 ENST00000337288.5
StAR-related lipid transfer (START) domain containing 7
chr1_+_155278539 95.62 ENST00000447866.1
farnesyl diphosphate synthase
chr9_-_95056010 95.38 ENST00000443024.2
isoleucyl-tRNA synthetase
chr20_-_54967187 95.28 ENST00000422322.1
aurora kinase A
chr5_+_162887556 94.76 ENST00000393915.4
hyaluronan-mediated motility receptor (RHAMM)
chr1_-_150208498 92.60 ENST00000314136.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr5_+_74632993 91.86 ENST00000287936.4
3-hydroxy-3-methylglutaryl-CoA reductase
chr9_+_140135665 91.59 ENST00000340384.4
tubulin, beta 4B class IVb
chr12_-_102513843 91.32 ENST00000551744.2
nucleoporin 37kDa
chr8_-_25315905 90.93 ENST00000221200.4
potassium channel tetramerization domain containing 9
chr4_+_166248775 90.28 ENST00000261507.6
methylsterol monooxygenase 1
chr19_+_13049413 90.28 ENST00000316448.5
chr1_-_150208412 89.74 ENST00000532744.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr9_-_35103105 89.47 ENST00000452248.2
stomatin (EPB72)-like 2
chr19_-_8070474 89.00 ENST00000407627.2
ELAV like RNA binding protein 1
chr6_+_80714318 88.82 ENST00000369798.2
TTK protein kinase
chr17_+_45727204 88.64 ENST00000290158.4
karyopherin (importin) beta 1
chr1_+_155278625 88.48 ENST00000368356.4
farnesyl diphosphate synthase
chr17_-_5323480 88.27 ENST00000573584.1
nucleoporin 88kDa
chr8_+_11660120 88.25 ENST00000220584.4
farnesyl-diphosphate farnesyltransferase 1
chr9_-_128003606 88.04 ENST00000324460.6
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr17_-_79818354 87.68 ENST00000576541.1
prolyl 4-hydroxylase, beta polypeptide
chr14_-_55658252 87.07 ENST00000395425.2
discs, large (Drosophila) homolog-associated protein 5
chr6_-_18265050 86.79 ENST00000397239.3
DEK oncogene
chr1_-_150208363 86.76 ENST00000436748.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_-_49075941 86.65 ENST00000553086.1
KAT8 regulatory NSL complex subunit 2
chr1_+_181057638 86.64 ENST00000367577.4
immediate early response 5
chr7_-_30544405 86.21 ENST00000409390.1
chr17_+_1733276 86.09 ENST00000254719.5
replication protein A1, 70kDa
chr5_+_159848854 85.78 ENST00000517480.1
pituitary tumor-transforming 1
chr19_+_3572925 85.77 ENST00000333651.6
high mobility group 20B
chr14_-_23398565 84.88 ENST00000397440.4
protein arginine methyltransferase 5
chr6_+_160183492 84.86 ENST00000541436.1
acetyl-CoA acetyltransferase 2
chr3_+_37034823 84.27 ENST00000231790.2
mutL homolog 1
chr19_+_45394477 83.47 ENST00000252487.5
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_-_7680601 83.11 ENST00000396682.2
replication protein A3, 14kDa
chr8_-_66546439 82.61 ENST00000276569.3
armadillo repeat containing 1
chrX_+_150151752 81.57 ENST00000325307.7
high mobility group box 3
chr4_+_1723197 81.56 ENST00000485989.2
transforming, acidic coiled-coil containing protein 3
chr10_-_58120996 81.55 ENST00000361148.6
ZW10 interacting kinetochore protein
chr6_+_32146131 81.33 ENST00000375094.3
ring finger protein 5, E3 ubiquitin protein ligase
chr10_+_14880157 81.07 ENST00000378372.3
heat shock 70kDa protein 14
chr7_-_148725733 80.62 ENST00000286091.4
protein disulfide isomerase family A, member 4
chr2_+_191745560 80.60 ENST00000338435.4
chr19_-_18433875 80.56 ENST00000252816.6
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr19_+_49497121 80.07 ENST00000413176.2
RuvB-like AAA ATPase 2
chr14_-_55658323 79.62 ENST00000554067.1
discs, large (Drosophila) homolog-associated protein 5
chr15_-_41624685 79.54 ENST00000560640.1
Opa interacting protein 5
chr19_+_49496705 79.50 ENST00000595090.1
RuvB-like AAA ATPase 2
chr5_-_137878887 78.88 ENST00000507939.1
eukaryotic translation termination factor 1
chr20_+_30327063 78.40 ENST00000300403.6
TPX2, microtubule-associated
chr1_-_35658736 78.15 ENST00000357214.5
splicing factor proline/glutamine-rich
chr14_+_52456327 77.95 ENST00000556760.1
chromosome 14 open reading frame 166
chr4_-_100871506 77.64 ENST00000296417.5
H2A histone family, member Z
chr6_-_52149475 77.23 ENST00000419835.2
minichromosome maintenance complex component 3
chr5_+_44809027 76.78 ENST00000507110.1
mitochondrial ribosomal protein S30
chr19_-_18433910 75.83 ENST00000594828.3
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_-_46867780 75.47 ENST00000529230.1
cytoskeleton associated protein 5
chr8_+_6565854 74.68 ENST00000285518.6
1-acylglycerol-3-phosphate O-acyltransferase 5
chr2_-_111435610 74.48 ENST00000447014.1
BUB1 mitotic checkpoint serine/threonine kinase
chr22_+_19467261 74.34 ENST00000455750.1
cell division cycle 45
chr1_+_52082751 74.33 ENST00000447887.1
oxysterol binding protein-like 9
chr17_-_43025005 74.11 ENST00000587309.1
kinesin family member 18B
chr2_+_74425689 74.08 ENST00000394053.2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr1_-_27816641 73.52 ENST00000430629.2
WAS protein family, member 2
chr17_-_5322786 73.27 ENST00000225696.4
nucleoporin 88kDa
chr12_+_56618102 73.04 ENST00000267023.4
nucleic acid binding protein 2
chrX_-_100662881 72.55 ENST00000218516.3
galactosidase, alpha
chr20_+_3869423 72.39 ENST00000497424.1
pantothenate kinase 2
chr21_-_40720974 72.38 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr1_+_10459111 72.27 ENST00000541529.1
phosphogluconate dehydrogenase
chr12_+_109535373 72.02 ENST00000242576.2
uracil-DNA glycosylase
chr13_+_53029564 71.22 ENST00000468284.1
cytoskeleton associated protein 2
chr12_-_49076002 71.20 ENST00000357861.3
KAT8 regulatory NSL complex subunit 2
chr3_-_141868293 71.13 ENST00000317104.7
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_+_12727250 71.06 ENST00000404894.1
ADP-ribosylation factor-like 4A
chr16_+_69458537 71.04 ENST00000515314.1
cytochrome b5 type B (outer mitochondrial membrane)
chr11_+_57480046 70.97 ENST00000378312.4
thioredoxin-related transmembrane protein 2
chr4_-_1714037 70.80 ENST00000488267.1
stem-loop binding protein
chr11_+_95523621 70.51 ENST00000325542.5
centrosomal protein 57kDa
chr14_+_39644387 70.34 ENST00000553331.1
pinin, desmosome associated protein
chr17_-_79980734 70.05 ENST00000584600.1
stimulated by retinoic acid 13
chrX_+_48432892 69.64 ENST00000376759.3
RNA binding motif (RNP1, RRM) protein 3
chr13_-_31040060 69.31 ENST00000326004.4
high mobility group box 1
chr5_-_89705537 69.25 ENST00000522864.1
centrin, EF-hand protein, 3
chr17_+_18759612 69.24 ENST00000432893.2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr1_+_214776516 69.22 ENST00000366955.3
centromere protein F, 350/400kDa
chr16_+_69458428 69.04 ENST00000512062.1
cytochrome b5 type B (outer mitochondrial membrane)
chr12_+_121124921 68.75 ENST00000412616.2
chr1_-_28241226 68.51 ENST00000373912.3
replication protein A2, 32kDa
chr19_+_16222439 68.16 ENST00000300935.3
RAB8A, member RAS oncogene family
chr12_+_109535923 68.16 ENST00000336865.2
uracil-DNA glycosylase
chr11_-_64546202 68.12 ENST00000377390.3
splicing factor 1
chr20_+_35807449 67.95 ENST00000237530.6
ribophorin II
chr10_+_124913793 67.81 ENST00000368865.4
BUB3 mitotic checkpoint protein
chr6_+_27114861 67.72 ENST00000377459.1
histone cluster 1, H2ah
chr2_-_234763147 67.48 ENST00000411486.2
Holliday junction recognition protein
chr21_-_40720995 67.17 ENST00000380749.5
high mobility group nucleosome binding domain 1
chr20_-_5107180 67.09 ENST00000379160.3
proliferating cell nuclear antigen
chr7_-_151217166 66.93 ENST00000496004.1
Ras homolog enriched in brain
chr12_+_6603253 66.72 ENST00000382457.4
non-SMC condensin I complex, subunit D2
chr15_+_80351910 66.57 ENST00000261749.6
zinc finger, AN1-type domain 6
chr11_-_64545941 66.28 ENST00000377387.1
splicing factor 1
chr1_+_33116765 66.12 ENST00000544435.1
retinoblastoma binding protein 4
chr2_+_75061108 65.90 ENST00000290573.2
hexokinase 2
chr2_-_128784846 65.68 ENST00000259235.3
Sin3A-associated protein, 130kDa
chr14_+_52456193 65.64 ENST00000261700.3
chromosome 14 open reading frame 166
chrX_+_48380205 65.51 ENST00000446158.1
emopamil binding protein (sterol isomerase)
chr1_-_150208291 65.43 ENST00000533654.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr3_+_51422478 64.82 ENST00000528157.1
mesencephalic astrocyte-derived neurotrophic factor
chr6_-_27114577 64.43 ENST00000356950.1
histone cluster 1, H2bk
chr1_+_33116743 64.30 ENST00000414241.3
retinoblastoma binding protein 4
chr1_-_225615599 64.17 ENST00000421383.1
lamin B receptor
chr5_-_31532160 64.11 ENST00000511367.2
drosha, ribonuclease type III
chr1_-_149814478 64.04 ENST00000369161.3
histone cluster 2, H2aa3
chr13_+_73302047 63.79 ENST00000377814.2
bora, aurora kinase A activator
chr19_+_41770236 63.58 ENST00000392006.3
heterogeneous nuclear ribonucleoprotein U-like 1
chr15_-_64673665 63.38 ENST00000300035.4
chr1_+_32757668 63.32 ENST00000373548.3
histone deacetylase 1
chr15_+_80351977 63.16 ENST00000559157.1
zinc finger, AN1-type domain 6
chr4_-_122744998 63.12 ENST00000274026.5
cyclin A2
chr11_-_66056596 63.08 ENST00000471387.2
Yip1 interacting factor homolog A (S. cerevisiae)
chr14_+_97263641 63.04 ENST00000216639.3
vaccinia related kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
114.3 342.9 GO:2000775 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
104.5 313.6 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
92.5 740.3 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
61.2 306.0 GO:0016321 female meiosis chromosome segregation(GO:0016321)
54.1 216.5 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
52.2 313.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
51.7 206.6 GO:0006272 leading strand elongation(GO:0006272)
48.8 293.0 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
48.0 383.8 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
47.8 334.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
47.2 330.7 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
46.7 140.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
46.1 138.3 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
43.6 740.6 GO:0006265 DNA topological change(GO:0006265)
43.0 301.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
42.8 128.5 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
35.5 35.5 GO:1903405 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
33.0 165.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
33.0 164.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
32.7 130.8 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
31.7 380.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
31.4 94.1 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
31.3 156.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
29.6 88.7 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
29.3 88.0 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
28.5 114.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
27.3 54.6 GO:0005997 xylulose metabolic process(GO:0005997)
27.0 81.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
25.5 25.5 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
25.2 75.5 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
24.3 72.9 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
24.3 97.1 GO:0019322 pentose biosynthetic process(GO:0019322)
24.2 363.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
23.7 47.5 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
23.4 23.4 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
22.7 113.7 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
22.4 269.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
22.4 89.5 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296)
21.5 364.8 GO:0000920 cell separation after cytokinesis(GO:0000920)
21.3 63.8 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
21.1 105.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
20.9 20.9 GO:0031047 gene silencing by RNA(GO:0031047)
20.6 206.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
20.3 142.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
20.0 20.0 GO:0060623 regulation of chromosome condensation(GO:0060623)
19.8 59.4 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
19.7 296.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
19.4 58.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
19.4 154.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
19.3 192.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
19.0 874.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
18.9 94.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
18.6 18.6 GO:1904429 regulation of t-circle formation(GO:1904429) positive regulation of t-circle formation(GO:1904431)
18.3 55.0 GO:0071109 superior temporal gyrus development(GO:0071109)
18.3 182.9 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
17.4 104.6 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
17.3 52.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
17.2 292.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
16.6 49.9 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
16.6 49.8 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
16.5 33.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
16.5 610.6 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
16.5 49.5 GO:0007290 spermatid nucleus elongation(GO:0007290)
16.3 162.7 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
16.2 81.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
16.2 113.5 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
16.2 48.5 GO:0044209 AMP salvage(GO:0044209)
16.0 1022.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
15.8 47.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
15.7 31.5 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) dTTP metabolic process(GO:0046075)
15.7 47.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
15.6 156.5 GO:0015939 pantothenate metabolic process(GO:0015939)
15.6 78.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
15.5 46.6 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
15.5 93.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
15.5 31.0 GO:0009133 ADP biosynthetic process(GO:0006172) nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
15.4 46.3 GO:0048478 replication fork protection(GO:0048478)
15.4 184.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
15.2 76.2 GO:1904764 late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
15.2 1173.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
15.1 75.3 GO:2000035 regulation of stem cell division(GO:2000035)
15.0 30.0 GO:0035927 RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928)
14.9 311.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
14.7 383.1 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
14.6 29.2 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
14.2 28.5 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
13.9 55.6 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
13.8 69.1 GO:0002084 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
13.7 123.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
13.6 40.9 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
13.2 39.5 GO:0006106 fumarate metabolic process(GO:0006106)
13.0 39.1 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
12.9 64.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
12.9 102.9 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
12.6 188.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
12.5 50.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
12.2 48.9 GO:0002317 plasma cell differentiation(GO:0002317)
12.1 12.1 GO:0019046 release from viral latency(GO:0019046)
12.0 108.3 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
12.0 143.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
11.8 47.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
11.7 81.8 GO:0090224 regulation of spindle organization(GO:0090224)
11.6 34.9 GO:1901355 response to rapamycin(GO:1901355)
11.6 81.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
11.6 34.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
11.6 462.1 GO:0042407 cristae formation(GO:0042407)
11.1 77.7 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
11.1 55.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
10.7 85.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
10.5 189.4 GO:0007021 tubulin complex assembly(GO:0007021)
10.5 31.5 GO:0072237 isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) metanephric proximal tubule development(GO:0072237)
10.3 51.6 GO:0006543 glutamine catabolic process(GO:0006543)
10.3 615.8 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
10.1 80.7 GO:0016139 glycoside catabolic process(GO:0016139)
10.0 49.9 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
9.9 29.7 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
9.8 29.5 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
9.8 108.1 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
9.7 58.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
9.5 47.6 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
9.5 37.8 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
9.4 56.5 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
9.3 259.9 GO:0006270 DNA replication initiation(GO:0006270)
9.2 64.6 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
9.2 27.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
9.2 27.6 GO:1901873 regulation of post-translational protein modification(GO:1901873)
9.1 45.5 GO:0070647 protein modification by small protein conjugation or removal(GO:0070647)
9.0 35.9 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
9.0 89.7 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
9.0 80.6 GO:0006552 leucine catabolic process(GO:0006552)
8.9 71.1 GO:0048194 Golgi vesicle budding(GO:0048194)
8.9 26.6 GO:0021678 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
8.9 70.9 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
8.7 26.1 GO:0032765 lymphotoxin A production(GO:0032641) positive regulation of mast cell cytokine production(GO:0032765) lymphotoxin A biosynthetic process(GO:0042109)
8.7 43.4 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
8.6 129.4 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
8.6 333.5 GO:0000281 mitotic cytokinesis(GO:0000281)
8.5 59.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
8.4 33.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
8.4 386.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
8.3 24.8 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
8.1 32.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
8.1 510.5 GO:0032392 DNA geometric change(GO:0032392)
8.1 129.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
8.0 143.8 GO:0070200 establishment of protein localization to telomere(GO:0070200)
7.9 71.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
7.8 31.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
7.7 77.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
7.7 23.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
7.7 46.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
7.6 38.2 GO:0042816 vitamin B6 metabolic process(GO:0042816)
7.6 15.2 GO:0075528 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
7.6 189.1 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
7.5 60.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
7.5 7.5 GO:0090116 C-5 methylation of cytosine(GO:0090116)
7.5 89.7 GO:0006449 regulation of translational termination(GO:0006449)
7.4 133.9 GO:0061157 mRNA destabilization(GO:0061157)
7.4 52.0 GO:0003415 chondrocyte hypertrophy(GO:0003415)
7.4 88.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
7.3 14.6 GO:0070314 G1 to G0 transition(GO:0070314)
7.3 131.8 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
7.3 29.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
7.2 28.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
7.0 105.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
7.0 147.0 GO:0002192 IRES-dependent translational initiation(GO:0002192)
7.0 14.0 GO:0045900 negative regulation of translational elongation(GO:0045900)
6.9 20.7 GO:0032773 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
6.8 20.5 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
6.8 13.5 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
6.8 33.8 GO:0033591 response to L-ascorbic acid(GO:0033591)
6.8 33.8 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
6.8 101.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
6.7 20.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
6.7 20.0 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
6.6 72.7 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
6.6 26.4 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
6.6 39.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
6.5 39.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
6.5 26.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
6.4 19.3 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
6.4 460.5 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
6.4 25.4 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
6.3 31.5 GO:0031507 heterochromatin assembly(GO:0031507)
6.3 6.3 GO:0051595 response to methylglyoxal(GO:0051595)
6.3 31.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
6.3 162.7 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
6.2 236.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
6.2 18.5 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
6.2 18.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
6.2 135.7 GO:0006465 signal peptide processing(GO:0006465)
6.2 43.1 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
6.1 6.1 GO:0040031 snRNA modification(GO:0040031)
6.1 24.3 GO:0002880 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
6.0 6.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
6.0 23.9 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
6.0 29.8 GO:1990834 response to odorant(GO:1990834)
5.9 41.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
5.9 52.9 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
5.8 5.8 GO:0042118 endothelial cell activation(GO:0042118)
5.8 23.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
5.7 109.1 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
5.7 5.7 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
5.6 311.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
5.6 22.3 GO:0048496 maintenance of organ identity(GO:0048496)
5.6 22.2 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
5.5 160.9 GO:0006301 postreplication repair(GO:0006301)
5.5 16.6 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
5.5 16.6 GO:0042369 vitamin D catabolic process(GO:0042369)
5.5 22.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
5.5 33.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
5.5 121.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
5.4 16.3 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
5.3 10.6 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
5.3 21.2 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
5.3 21.2 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
5.2 36.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
5.2 36.4 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
5.2 15.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
5.1 15.3 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
5.1 71.4 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
5.1 15.3 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
5.0 5.0 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
5.0 65.4 GO:0043248 proteasome assembly(GO:0043248)
5.0 24.9 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
5.0 34.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
5.0 19.8 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
4.9 34.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
4.9 9.8 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
4.9 38.9 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
4.8 48.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
4.8 23.8 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
4.7 14.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
4.7 9.4 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
4.7 42.3 GO:0043968 histone H2A acetylation(GO:0043968)
4.7 56.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
4.7 271.9 GO:0006342 chromatin silencing(GO:0006342)
4.5 340.9 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
4.4 22.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
4.4 13.3 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
4.4 17.7 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
4.4 8.8 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
4.4 22.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
4.4 8.8 GO:1903626 positive regulation of DNA catabolic process(GO:1903626)
4.4 26.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
4.4 56.7 GO:0019054 modulation by virus of host process(GO:0019054)
4.3 260.0 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
4.3 34.0 GO:0006689 ganglioside catabolic process(GO:0006689)
4.2 63.5 GO:0000338 protein deneddylation(GO:0000338)
4.2 274.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
4.2 29.4 GO:0060155 platelet dense granule organization(GO:0060155)
4.1 12.4 GO:0072719 cellular response to cisplatin(GO:0072719)
4.1 24.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
4.1 28.9 GO:0010507 negative regulation of autophagy(GO:0010507)
4.1 93.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
4.0 36.3 GO:0045008 depyrimidination(GO:0045008)
4.0 40.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
4.0 20.0 GO:0000733 DNA strand renaturation(GO:0000733)
4.0 12.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
4.0 43.8 GO:1903800 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
4.0 43.8 GO:0006337 nucleosome disassembly(GO:0006337)
3.9 15.7 GO:0007144 female meiosis I(GO:0007144)
3.9 62.7 GO:1903540 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
3.9 19.5 GO:0030047 actin modification(GO:0030047)
3.8 61.2 GO:0051639 actin filament network formation(GO:0051639)
3.8 30.5 GO:0009249 protein lipoylation(GO:0009249)
3.8 3.8 GO:1990144 intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
3.8 18.9 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
3.8 60.6 GO:0042113 B cell activation(GO:0042113)
3.8 135.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
3.8 75.0 GO:0035855 megakaryocyte development(GO:0035855)
3.7 30.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
3.7 7.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
3.7 22.0 GO:0070836 caveola assembly(GO:0070836)
3.7 3.7 GO:0031291 Ran protein signal transduction(GO:0031291)
3.6 50.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
3.6 3.6 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465) positive regulation of glycogen (starch) synthase activity(GO:2000467)
3.6 10.8 GO:0043132 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
3.6 180.3 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
3.6 25.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
3.5 56.0 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
3.5 10.5 GO:0034982 mitochondrial protein processing(GO:0034982)
3.4 10.3 GO:0051135 positive regulation of NK T cell activation(GO:0051135)
3.4 51.2 GO:0045116 protein neddylation(GO:0045116)
3.4 249.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
3.4 6.8 GO:0090427 activation of meiosis(GO:0090427)
3.4 70.7 GO:0006750 glutathione biosynthetic process(GO:0006750)
3.2 45.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
3.2 12.7 GO:0014894 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
3.2 22.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
3.1 6.2 GO:0046449 creatinine metabolic process(GO:0046449)
3.1 9.3 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
3.0 6.0 GO:0070541 response to platinum ion(GO:0070541)
3.0 33.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
3.0 33.0 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
3.0 211.1 GO:0045454 cell redox homeostasis(GO:0045454)
3.0 8.9 GO:0072718 response to cisplatin(GO:0072718)
2.9 8.8 GO:1904526 regulation of microtubule binding(GO:1904526)
2.9 23.2 GO:0061042 vascular wound healing(GO:0061042)
2.9 8.7 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
2.8 8.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
2.8 14.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
2.7 10.9 GO:1903826 arginine transmembrane transport(GO:1903826)
2.7 147.7 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
2.7 21.8 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
2.7 10.9 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
2.7 10.8 GO:0043967 histone H4 acetylation(GO:0043967)
2.7 2.7 GO:0006624 vacuolar protein processing(GO:0006624)
2.7 10.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
2.7 37.2 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
2.6 7.9 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
2.6 31.8 GO:0035372 protein localization to microtubule(GO:0035372)
2.6 5.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
2.6 10.5 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
2.6 15.6 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
2.6 20.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
2.6 5.2 GO:0060696 regulation of phospholipid catabolic process(GO:0060696)
2.6 72.3 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
2.6 59.2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
2.5 30.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
2.5 35.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
2.5 5.1 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
2.5 32.8 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
2.5 148.3 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
2.5 12.5 GO:0070574 cadmium ion transport(GO:0015691) lead ion transport(GO:0015692) cadmium ion transmembrane transport(GO:0070574)
2.5 7.4 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
2.5 12.4 GO:0015862 uridine transport(GO:0015862)
2.5 73.8 GO:0045739 positive regulation of DNA repair(GO:0045739)
2.5 14.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
2.5 9.8 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
2.4 16.9 GO:0006868 glutamine transport(GO:0006868)
2.4 7.3 GO:0006597 spermine biosynthetic process(GO:0006597)
2.4 55.1 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
2.4 4.8 GO:0051084 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
2.4 26.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
2.4 30.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
2.3 18.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
2.3 49.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
2.3 11.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
2.3 6.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
2.2 38.2 GO:0071451 removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
2.2 35.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
2.2 24.5 GO:0033197 response to vitamin E(GO:0033197)
2.2 4.4 GO:0006059 hexitol metabolic process(GO:0006059)
2.1 4.3 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
2.1 40.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
2.1 8.5 GO:1901727 protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
2.1 27.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
2.1 8.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
2.1 16.6 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
2.1 8.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
2.1 4.1 GO:0070141 response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492)
2.0 12.1 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
2.0 24.2 GO:0090527 actin filament reorganization(GO:0090527)
2.0 48.3 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
2.0 12.0 GO:0070933 histone H4 deacetylation(GO:0070933)
2.0 10.0 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.0 6.0 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
2.0 9.9 GO:0006011 UDP-glucose metabolic process(GO:0006011)
2.0 58.9 GO:0000060 protein import into nucleus, translocation(GO:0000060)
1.9 1.9 GO:0051182 coenzyme transport(GO:0051182)
1.9 438.4 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
1.9 5.8 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
1.9 17.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
1.9 21.4 GO:0051451 myoblast migration(GO:0051451)
1.9 57.2 GO:0043388 positive regulation of DNA binding(GO:0043388)
1.9 30.3 GO:0018345 protein palmitoylation(GO:0018345)
1.8 7.4 GO:0070302 regulation of stress-activated MAPK cascade(GO:0032872) regulation of stress-activated protein kinase signaling cascade(GO:0070302)
1.8 34.9 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
1.8 146.8 GO:0006353 DNA-templated transcription, termination(GO:0006353)
1.8 23.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
1.8 18.3 GO:0036258 multivesicular body organization(GO:0036257) multivesicular body assembly(GO:0036258)
1.8 21.8 GO:0045727 positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727)
1.8 21.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.8 33.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
1.8 17.7 GO:0044728 DNA methylation or demethylation(GO:0044728)
1.8 14.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
1.7 73.0 GO:0006611 protein export from nucleus(GO:0006611)
1.7 10.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
1.7 46.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.7 5.2 GO:0051697 protein delipidation(GO:0051697)
1.7 42.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
1.7 8.6 GO:0030316 osteoclast differentiation(GO:0030316)
1.7 6.8 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
1.7 8.4 GO:0034637 cellular carbohydrate biosynthetic process(GO:0034637)
1.7 15.0 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
1.6 8.2 GO:0060022 hard palate development(GO:0060022)
1.6 8.2 GO:0048254 snoRNA localization(GO:0048254)
1.6 4.8 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
1.6 7.9 GO:1905146 lysosomal protein catabolic process(GO:1905146)
1.6 3.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
1.6 14.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
1.6 9.4 GO:0006013 mannose metabolic process(GO:0006013)
1.5 27.6 GO:0036010 protein localization to endosome(GO:0036010)
1.5 13.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
1.5 4.5 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.5 10.3 GO:0007258 JUN phosphorylation(GO:0007258)
1.5 11.8 GO:0051660 establishment of centrosome localization(GO:0051660)
1.5 38.1 GO:0031648 protein destabilization(GO:0031648)
1.4 1.4 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
1.4 1.4 GO:0070828 heterochromatin organization(GO:0070828)
1.4 4.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
1.4 56.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
1.4 8.3 GO:0060736 prostate gland growth(GO:0060736)
1.4 15.2 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
1.4 2.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.4 13.6 GO:0031639 plasminogen activation(GO:0031639)
1.4 98.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.3 8.1 GO:0090161 Golgi ribbon formation(GO:0090161)
1.3 5.3 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
1.3 2.7 GO:0071609 chemokine (C-C motif) ligand 5 production(GO:0071609)
1.3 47.9 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
1.3 13.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
1.3 21.2 GO:0006491 N-glycan processing(GO:0006491)
1.3 13.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
1.3 3.9 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.3 3.9 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.3 1.3 GO:0051030 snRNA transport(GO:0051030)
1.3 2.6 GO:2000491 hepatic stellate cell activation(GO:0035733) regulation of hepatic stellate cell activation(GO:2000489) positive regulation of hepatic stellate cell activation(GO:2000491)
1.3 3.9 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.3 5.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
1.3 7.6 GO:0042262 DNA protection(GO:0042262)
1.3 3.8 GO:1903313 positive regulation of mRNA metabolic process(GO:1903313)
1.2 8.7 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
1.2 3.7 GO:0044275 cellular carbohydrate catabolic process(GO:0044275)
1.2 2.5 GO:0042938 dipeptide transport(GO:0042938)
1.2 33.2 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
1.2 3.7 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
1.2 16.8 GO:0002021 response to dietary excess(GO:0002021)