Project
averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
Z-value: 8.82
Motif logo
Transcription factors associated with YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
YBX1
|
ENSG00000065978.13 | Y-box binding protein 1 |
|
FOS
|
ENSG00000170345.5 | Fos proto-oncogene, AP-1 transcription factor subunit |
|
NFYC
|
ENSG00000066136.15 | nuclear transcription factor Y subunit gamma |
|
NFYA
|
ENSG00000001167.10 | nuclear transcription factor Y subunit alpha |
|
NFYB
|
ENSG00000120837.3 | nuclear transcription factor Y subunit beta |
|
CEBPZ
|
ENSG00000115816.9 | CCAAT enhancer binding protein zeta |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CEBPZ | hg19_v2_chr2_-_37458749_37458856 | 0.83 | 2.9e-56 | Click! |
| YBX1 | hg19_v2_chr1_+_43148625_43148710 | 0.78 | 1.9e-46 | Click! |
| NFYC | hg19_v2_chr1_+_41204506_41204541 | 0.69 | 5.4e-32 | Click! |
| NFYB | hg19_v2_chr12_-_104531945_104531996 | 0.54 | 4.1e-18 | Click! |
| FOS | hg19_v2_chr14_+_75745477_75745680 | -0.40 | 1.3e-09 | Click! |
| NFYA | hg19_v2_chr6_+_41040678_41040722 | -0.02 | 8.1e-01 | Click! |
Activity profile of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif
Sorted Z-values of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif
Network of associatons between targets according to the STRING database.
First level regulatory network of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 114.3 | 342.9 | GO:2000775 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775) |
| 104.5 | 313.6 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
| 92.5 | 740.3 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 61.2 | 306.0 | GO:0016321 | female meiosis chromosome segregation(GO:0016321) |
| 54.1 | 216.5 | GO:0090579 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 52.2 | 313.2 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 51.7 | 206.6 | GO:0006272 | leading strand elongation(GO:0006272) |
| 48.8 | 293.0 | GO:0014038 | regulation of Schwann cell differentiation(GO:0014038) |
| 48.0 | 383.8 | GO:0090306 | spindle assembly involved in meiosis(GO:0090306) |
| 47.8 | 334.6 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 47.2 | 330.7 | GO:0016128 | phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129) |
| 46.7 | 140.1 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 46.1 | 138.3 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 43.6 | 740.6 | GO:0006265 | DNA topological change(GO:0006265) |
| 43.0 | 301.3 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 42.8 | 128.5 | GO:0090155 | negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) |
| 35.5 | 35.5 | GO:1903405 | protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
| 33.0 | 165.1 | GO:0045338 | farnesyl diphosphate metabolic process(GO:0045338) |
| 33.0 | 164.9 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 32.7 | 130.8 | GO:0046104 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 31.7 | 380.8 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 31.4 | 94.1 | GO:0033489 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 31.3 | 156.5 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 29.6 | 88.7 | GO:0072334 | UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334) |
| 29.3 | 88.0 | GO:0021589 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
| 28.5 | 114.1 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 27.3 | 54.6 | GO:0005997 | xylulose metabolic process(GO:0005997) |
| 27.0 | 81.1 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 25.5 | 25.5 | GO:1903181 | regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) |
| 25.2 | 75.5 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
| 24.3 | 72.9 | GO:2000374 | regulation of oxygen metabolic process(GO:2000374) |
| 24.3 | 97.1 | GO:0019322 | pentose biosynthetic process(GO:0019322) |
| 24.2 | 363.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 23.7 | 47.5 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 23.4 | 23.4 | GO:1904815 | negative regulation of protein localization to chromosome, telomeric region(GO:1904815) |
| 22.7 | 113.7 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 22.4 | 269.1 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 22.4 | 89.5 | GO:0090296 | regulation of mitochondrial DNA replication(GO:0090296) |
| 21.5 | 364.8 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 21.3 | 63.8 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
| 21.1 | 105.6 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 20.9 | 20.9 | GO:0031047 | gene silencing by RNA(GO:0031047) |
| 20.6 | 206.1 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 20.3 | 142.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 20.0 | 20.0 | GO:0060623 | regulation of chromosome condensation(GO:0060623) |
| 19.8 | 59.4 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 19.7 | 296.1 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 19.4 | 58.3 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 19.4 | 154.9 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 19.3 | 192.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 19.0 | 874.1 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 18.9 | 94.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 18.6 | 18.6 | GO:1904429 | regulation of t-circle formation(GO:1904429) positive regulation of t-circle formation(GO:1904431) |
| 18.3 | 55.0 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
| 18.3 | 182.9 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 17.4 | 104.6 | GO:0030581 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 17.3 | 52.0 | GO:0006425 | glutaminyl-tRNA aminoacylation(GO:0006425) |
| 17.2 | 292.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 16.6 | 49.9 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 16.6 | 49.8 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 16.5 | 33.1 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 16.5 | 610.6 | GO:2000816 | negative regulation of mitotic sister chromatid separation(GO:2000816) |
| 16.5 | 49.5 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 16.3 | 162.7 | GO:0007091 | metaphase/anaphase transition of mitotic cell cycle(GO:0007091) |
| 16.2 | 81.1 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 16.2 | 113.5 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 16.2 | 48.5 | GO:0044209 | AMP salvage(GO:0044209) |
| 16.0 | 1022.7 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 15.8 | 47.3 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 15.7 | 31.5 | GO:0009211 | pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) dTTP metabolic process(GO:0046075) |
| 15.7 | 47.1 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 15.6 | 156.5 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 15.6 | 78.2 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 15.5 | 46.6 | GO:1904247 | positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 15.5 | 93.1 | GO:0055129 | proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129) |
| 15.5 | 31.0 | GO:0009133 | ADP biosynthetic process(GO:0006172) nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188) |
| 15.4 | 46.3 | GO:0048478 | replication fork protection(GO:0048478) |
| 15.4 | 184.7 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 15.2 | 76.2 | GO:1904764 | late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 15.2 | 1173.9 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 15.1 | 75.3 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 15.0 | 30.0 | GO:0035927 | RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928) |
| 14.9 | 311.9 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 14.7 | 383.1 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 14.6 | 29.2 | GO:0000912 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 14.2 | 28.5 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 13.9 | 55.6 | GO:2001166 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 13.8 | 69.1 | GO:0002084 | protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 13.7 | 123.3 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
| 13.6 | 40.9 | GO:0070638 | nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) |
| 13.2 | 39.5 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 13.0 | 39.1 | GO:0070510 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
| 12.9 | 64.4 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 12.9 | 102.9 | GO:0042761 | fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 12.6 | 188.7 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 12.5 | 50.1 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 12.2 | 48.9 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 12.1 | 12.1 | GO:0019046 | release from viral latency(GO:0019046) |
| 12.0 | 108.3 | GO:1903297 | regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) |
| 12.0 | 143.6 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 11.8 | 47.1 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 11.7 | 81.8 | GO:0090224 | regulation of spindle organization(GO:0090224) |
| 11.6 | 34.9 | GO:1901355 | response to rapamycin(GO:1901355) |
| 11.6 | 81.1 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 11.6 | 34.7 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 11.6 | 462.1 | GO:0042407 | cristae formation(GO:0042407) |
| 11.1 | 77.7 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 11.1 | 55.3 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 10.7 | 85.7 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 10.5 | 189.4 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 10.5 | 31.5 | GO:0072237 | isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) metanephric proximal tubule development(GO:0072237) |
| 10.3 | 51.6 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 10.3 | 615.8 | GO:0007077 | mitotic nuclear envelope disassembly(GO:0007077) |
| 10.1 | 80.7 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 10.0 | 49.9 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 9.9 | 29.7 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
| 9.8 | 29.5 | GO:0035087 | targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087) |
| 9.8 | 108.1 | GO:2000576 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 9.7 | 58.3 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 9.5 | 47.6 | GO:2000781 | positive regulation of double-strand break repair(GO:2000781) |
| 9.5 | 37.8 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 9.4 | 56.5 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 9.3 | 259.9 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 9.2 | 64.6 | GO:0090650 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 9.2 | 27.6 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 9.2 | 27.6 | GO:1901873 | regulation of post-translational protein modification(GO:1901873) |
| 9.1 | 45.5 | GO:0070647 | protein modification by small protein conjugation or removal(GO:0070647) |
| 9.0 | 35.9 | GO:0071681 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) |
| 9.0 | 89.7 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 9.0 | 80.6 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 8.9 | 71.1 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 8.9 | 26.6 | GO:0021678 | fourth ventricle development(GO:0021592) third ventricle development(GO:0021678) |
| 8.9 | 70.9 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 8.7 | 26.1 | GO:0032765 | lymphotoxin A production(GO:0032641) positive regulation of mast cell cytokine production(GO:0032765) lymphotoxin A biosynthetic process(GO:0042109) |
| 8.7 | 43.4 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 8.6 | 129.4 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
| 8.6 | 333.5 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 8.5 | 59.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 8.4 | 33.6 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 8.4 | 386.0 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 8.3 | 24.8 | GO:0045658 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 8.1 | 32.4 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 8.1 | 510.5 | GO:0032392 | DNA geometric change(GO:0032392) |
| 8.1 | 129.0 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 8.0 | 143.8 | GO:0070200 | establishment of protein localization to telomere(GO:0070200) |
| 7.9 | 71.3 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 7.8 | 31.2 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 7.7 | 77.3 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 7.7 | 23.1 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 7.7 | 46.0 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 7.6 | 38.2 | GO:0042816 | vitamin B6 metabolic process(GO:0042816) |
| 7.6 | 15.2 | GO:0075528 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) |
| 7.6 | 189.1 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 7.5 | 60.4 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 7.5 | 7.5 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) |
| 7.5 | 89.7 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 7.4 | 133.9 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 7.4 | 52.0 | GO:0003415 | chondrocyte hypertrophy(GO:0003415) |
| 7.4 | 88.4 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 7.3 | 14.6 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 7.3 | 131.8 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 7.3 | 29.1 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 7.2 | 28.7 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 7.0 | 105.1 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 7.0 | 147.0 | GO:0002192 | IRES-dependent translational initiation(GO:0002192) |
| 7.0 | 14.0 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
| 6.9 | 20.7 | GO:0032773 | regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910) |
| 6.8 | 20.5 | GO:2000687 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 6.8 | 13.5 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 6.8 | 33.8 | GO:0033591 | response to L-ascorbic acid(GO:0033591) |
| 6.8 | 33.8 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 6.8 | 101.3 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 6.7 | 20.2 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 6.7 | 20.0 | GO:0030860 | regulation of polarized epithelial cell differentiation(GO:0030860) |
| 6.6 | 72.7 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 6.6 | 26.4 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 6.6 | 39.6 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 6.5 | 39.3 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 6.5 | 26.0 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 6.4 | 19.3 | GO:0006258 | UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499) |
| 6.4 | 460.5 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
| 6.4 | 25.4 | GO:0072367 | regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) |
| 6.3 | 31.5 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 6.3 | 6.3 | GO:0051595 | response to methylglyoxal(GO:0051595) |
| 6.3 | 31.4 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 6.3 | 162.7 | GO:0072663 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 6.2 | 236.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 6.2 | 18.5 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 6.2 | 18.5 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 6.2 | 135.7 | GO:0006465 | signal peptide processing(GO:0006465) |
| 6.2 | 43.1 | GO:0090343 | positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774) |
| 6.1 | 6.1 | GO:0040031 | snRNA modification(GO:0040031) |
| 6.1 | 24.3 | GO:0002880 | chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) |
| 6.0 | 6.0 | GO:0006286 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) |
| 6.0 | 23.9 | GO:0017198 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 6.0 | 29.8 | GO:1990834 | response to odorant(GO:1990834) |
| 5.9 | 41.5 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 5.9 | 52.9 | GO:0009113 | purine nucleobase biosynthetic process(GO:0009113) |
| 5.8 | 5.8 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 5.8 | 23.2 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
| 5.7 | 109.1 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 5.7 | 5.7 | GO:0061031 | endodermal digestive tract morphogenesis(GO:0061031) |
| 5.6 | 311.8 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 5.6 | 22.3 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 5.6 | 22.2 | GO:0072308 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697) |
| 5.5 | 160.9 | GO:0006301 | postreplication repair(GO:0006301) |
| 5.5 | 16.6 | GO:0002731 | negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253) |
| 5.5 | 16.6 | GO:0042369 | vitamin D catabolic process(GO:0042369) |
| 5.5 | 22.1 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 5.5 | 33.1 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 5.5 | 121.2 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 5.4 | 16.3 | GO:1902303 | regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303) |
| 5.3 | 10.6 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 5.3 | 21.2 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 5.3 | 21.2 | GO:0060751 | epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751) |
| 5.2 | 36.5 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 5.2 | 36.4 | GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 5.2 | 15.5 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 5.1 | 15.3 | GO:0043095 | regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105) |
| 5.1 | 71.4 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 5.1 | 15.3 | GO:0072282 | metanephric nephron tubule morphogenesis(GO:0072282) |
| 5.0 | 5.0 | GO:0036506 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 5.0 | 65.4 | GO:0043248 | proteasome assembly(GO:0043248) |
| 5.0 | 24.9 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 5.0 | 34.8 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 5.0 | 19.8 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 4.9 | 34.4 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 4.9 | 9.8 | GO:0002331 | pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331) |
| 4.9 | 38.9 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 4.8 | 48.5 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 4.8 | 23.8 | GO:0003069 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 4.7 | 14.2 | GO:0051305 | chromosome movement towards spindle pole(GO:0051305) |
| 4.7 | 9.4 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 4.7 | 42.3 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 4.7 | 56.3 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 4.7 | 271.9 | GO:0006342 | chromatin silencing(GO:0006342) |
| 4.5 | 340.9 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 4.4 | 22.2 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 4.4 | 13.3 | GO:0016260 | selenocysteine biosynthetic process(GO:0016260) |
| 4.4 | 17.7 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 4.4 | 8.8 | GO:0006864 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 4.4 | 22.1 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 4.4 | 8.8 | GO:1903626 | positive regulation of DNA catabolic process(GO:1903626) |
| 4.4 | 26.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 4.4 | 56.7 | GO:0019054 | modulation by virus of host process(GO:0019054) |
| 4.3 | 260.0 | GO:0051439 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) |
| 4.3 | 34.0 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 4.2 | 63.5 | GO:0000338 | protein deneddylation(GO:0000338) |
| 4.2 | 274.1 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 4.2 | 29.4 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 4.1 | 12.4 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
| 4.1 | 24.8 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 4.1 | 28.9 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 4.1 | 93.7 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 4.0 | 36.3 | GO:0045008 | depyrimidination(GO:0045008) |
| 4.0 | 40.2 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 4.0 | 20.0 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 4.0 | 12.0 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 4.0 | 43.8 | GO:1903800 | regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 4.0 | 43.8 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 3.9 | 15.7 | GO:0007144 | female meiosis I(GO:0007144) |
| 3.9 | 62.7 | GO:1903540 | neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540) |
| 3.9 | 19.5 | GO:0030047 | actin modification(GO:0030047) |
| 3.8 | 61.2 | GO:0051639 | actin filament network formation(GO:0051639) |
| 3.8 | 30.5 | GO:0009249 | protein lipoylation(GO:0009249) |
| 3.8 | 3.8 | GO:1990144 | intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144) |
| 3.8 | 18.9 | GO:0051299 | mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299) |
| 3.8 | 60.6 | GO:0042113 | B cell activation(GO:0042113) |
| 3.8 | 135.7 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 3.8 | 75.0 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 3.7 | 30.0 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 3.7 | 7.4 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 3.7 | 22.0 | GO:0070836 | caveola assembly(GO:0070836) |
| 3.7 | 3.7 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 3.6 | 50.8 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 3.6 | 3.6 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 3.6 | 10.8 | GO:0043132 | FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132) |
| 3.6 | 180.3 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 3.6 | 25.1 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 3.5 | 56.0 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 3.5 | 10.5 | GO:0034982 | mitochondrial protein processing(GO:0034982) |
| 3.4 | 10.3 | GO:0051135 | positive regulation of NK T cell activation(GO:0051135) |
| 3.4 | 51.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 3.4 | 249.1 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 3.4 | 6.8 | GO:0090427 | activation of meiosis(GO:0090427) |
| 3.4 | 70.7 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 3.2 | 45.1 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 3.2 | 12.7 | GO:0014894 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 3.2 | 22.2 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 3.1 | 6.2 | GO:0046449 | creatinine metabolic process(GO:0046449) |
| 3.1 | 9.3 | GO:0002326 | B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152) |
| 3.0 | 6.0 | GO:0070541 | response to platinum ion(GO:0070541) |
| 3.0 | 33.0 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 3.0 | 33.0 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 3.0 | 211.1 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 3.0 | 8.9 | GO:0072718 | response to cisplatin(GO:0072718) |
| 2.9 | 8.8 | GO:1904526 | regulation of microtubule binding(GO:1904526) |
| 2.9 | 23.2 | GO:0061042 | vascular wound healing(GO:0061042) |
| 2.9 | 8.7 | GO:1904504 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
| 2.8 | 8.5 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 2.8 | 14.1 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 2.7 | 10.9 | GO:1903826 | arginine transmembrane transport(GO:1903826) |
| 2.7 | 147.7 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 2.7 | 21.8 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 2.7 | 10.9 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
| 2.7 | 10.8 | GO:0043967 | histone H4 acetylation(GO:0043967) |
| 2.7 | 2.7 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 2.7 | 10.7 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 2.7 | 37.2 | GO:0045814 | negative regulation of gene expression, epigenetic(GO:0045814) |
| 2.6 | 7.9 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 2.6 | 31.8 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 2.6 | 5.2 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 2.6 | 10.5 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 2.6 | 15.6 | GO:0031087 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 2.6 | 20.8 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 2.6 | 5.2 | GO:0060696 | regulation of phospholipid catabolic process(GO:0060696) |
| 2.6 | 72.3 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 2.6 | 59.2 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 2.5 | 30.5 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 2.5 | 35.6 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 2.5 | 5.1 | GO:0036260 | 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 2.5 | 32.8 | GO:0000478 | endonucleolytic cleavage involved in rRNA processing(GO:0000478) |
| 2.5 | 148.3 | GO:0042267 | natural killer cell mediated cytotoxicity(GO:0042267) |
| 2.5 | 12.5 | GO:0070574 | cadmium ion transport(GO:0015691) lead ion transport(GO:0015692) cadmium ion transmembrane transport(GO:0070574) |
| 2.5 | 7.4 | GO:0071043 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 2.5 | 12.4 | GO:0015862 | uridine transport(GO:0015862) |
| 2.5 | 73.8 | GO:0045739 | positive regulation of DNA repair(GO:0045739) |
| 2.5 | 14.7 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 2.5 | 9.8 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 2.4 | 16.9 | GO:0006868 | glutamine transport(GO:0006868) |
| 2.4 | 7.3 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 2.4 | 55.1 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
| 2.4 | 4.8 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 2.4 | 26.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 2.4 | 30.7 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 2.3 | 18.8 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
| 2.3 | 49.0 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 2.3 | 11.6 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 2.3 | 6.8 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 2.2 | 38.2 | GO:0071451 | removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) |
| 2.2 | 35.7 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 2.2 | 24.5 | GO:0033197 | response to vitamin E(GO:0033197) |
| 2.2 | 4.4 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 2.1 | 4.3 | GO:0031441 | negative regulation of mRNA 3'-end processing(GO:0031441) |
| 2.1 | 40.6 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 2.1 | 8.5 | GO:1901727 | protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727) |
| 2.1 | 27.5 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 2.1 | 8.3 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 2.1 | 16.6 | GO:0010917 | negative regulation of mitochondrial membrane potential(GO:0010917) |
| 2.1 | 8.3 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 2.1 | 4.1 | GO:0070141 | response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492) |
| 2.0 | 12.1 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 2.0 | 24.2 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 2.0 | 48.3 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 2.0 | 12.0 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 2.0 | 10.0 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 2.0 | 6.0 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
| 2.0 | 9.9 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
| 2.0 | 58.9 | GO:0000060 | protein import into nucleus, translocation(GO:0000060) |
| 1.9 | 1.9 | GO:0051182 | coenzyme transport(GO:0051182) |
| 1.9 | 438.4 | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 1.9 | 5.8 | GO:0060178 | regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178) |
| 1.9 | 17.5 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 1.9 | 21.4 | GO:0051451 | myoblast migration(GO:0051451) |
| 1.9 | 57.2 | GO:0043388 | positive regulation of DNA binding(GO:0043388) |
| 1.9 | 30.3 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 1.8 | 7.4 | GO:0070302 | regulation of stress-activated MAPK cascade(GO:0032872) regulation of stress-activated protein kinase signaling cascade(GO:0070302) |
| 1.8 | 34.9 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 1.8 | 146.8 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 1.8 | 23.8 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 1.8 | 18.3 | GO:0036258 | multivesicular body organization(GO:0036257) multivesicular body assembly(GO:0036258) |
| 1.8 | 21.8 | GO:0045727 | positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727) |
| 1.8 | 21.6 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 1.8 | 33.7 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 1.8 | 17.7 | GO:0044728 | DNA methylation or demethylation(GO:0044728) |
| 1.8 | 14.1 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 1.7 | 73.0 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 1.7 | 10.4 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 1.7 | 46.7 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 1.7 | 5.2 | GO:0051697 | protein delipidation(GO:0051697) |
| 1.7 | 42.8 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 1.7 | 8.6 | GO:0030316 | osteoclast differentiation(GO:0030316) |
| 1.7 | 6.8 | GO:0044821 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 1.7 | 8.4 | GO:0034637 | cellular carbohydrate biosynthetic process(GO:0034637) |
| 1.7 | 15.0 | GO:0006024 | aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024) |
| 1.6 | 8.2 | GO:0060022 | hard palate development(GO:0060022) |
| 1.6 | 8.2 | GO:0048254 | snoRNA localization(GO:0048254) |
| 1.6 | 4.8 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
| 1.6 | 7.9 | GO:1905146 | lysosomal protein catabolic process(GO:1905146) |
| 1.6 | 3.2 | GO:0060266 | negative regulation of respiratory burst involved in inflammatory response(GO:0060266) |
| 1.6 | 14.1 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 1.6 | 9.4 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 1.5 | 27.6 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 1.5 | 13.7 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 1.5 | 4.5 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 1.5 | 10.3 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 1.5 | 11.8 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
| 1.5 | 38.1 | GO:0031648 | protein destabilization(GO:0031648) |
| 1.4 | 1.4 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
| 1.4 | 1.4 | GO:0070828 | heterochromatin organization(GO:0070828) |
| 1.4 | 4.2 | GO:0048203 | vesicle targeting, trans-Golgi to endosome(GO:0048203) |
| 1.4 | 56.9 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 1.4 | 8.3 | GO:0060736 | prostate gland growth(GO:0060736) |
| 1.4 | 15.2 | GO:0051195 | negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198) |
| 1.4 | 2.7 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 1.4 | 13.6 | GO:0031639 | plasminogen activation(GO:0031639) |
| 1.4 | 98.6 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 1.3 | 8.1 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 1.3 | 5.3 | GO:1902513 | regulation of organelle transport along microtubule(GO:1902513) |
| 1.3 | 2.7 | GO:0071609 | chemokine (C-C motif) ligand 5 production(GO:0071609) |
| 1.3 | 47.9 | GO:0035306 | positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307) |
| 1.3 | 13.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 1.3 | 21.2 | GO:0006491 | N-glycan processing(GO:0006491) |
| 1.3 | 13.2 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 1.3 | 3.9 | GO:0070272 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 1.3 | 3.9 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 1.3 | 1.3 | GO:0051030 | snRNA transport(GO:0051030) |
| 1.3 | 2.6 | GO:2000491 | hepatic stellate cell activation(GO:0035733) regulation of hepatic stellate cell activation(GO:2000489) positive regulation of hepatic stellate cell activation(GO:2000491) |
| 1.3 | 3.9 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 1.3 | 5.1 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 1.3 | 7.6 | GO:0042262 | DNA protection(GO:0042262) |
| 1.3 | 3.8 | GO:1903313 | positive regulation of mRNA metabolic process(GO:1903313) |
| 1.2 | 8.7 | GO:0001916 | positive regulation of T cell mediated cytotoxicity(GO:0001916) |
| 1.2 | 3.7 | GO:0044275 | cellular carbohydrate catabolic process(GO:0044275) |
| 1.2 | 2.5 | GO:0042938 | dipeptide transport(GO:0042938) |
| 1.2 | 33.2 | GO:0006505 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
| 1.2 | 3.7 | GO:0019418 | sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) |
| 1.2 | 16.8 | GO:0002021 | response to dietary excess(GO:0002021) |
| 1.2 | 3.6 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 1.2 | 4.7 | GO:0097278 | complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) |
| 1.2 | 24.8 | GO:0030488 | tRNA methylation(GO:0030488) |
| 1.2 | 14.1 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 1.2 | 7.0 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 1.2 | 2.3 | GO:0046946 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 1.2 | 24.3 | GO:0009226 | nucleotide-sugar biosynthetic process(GO:0009226) |
| 1.2 | 6.9 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
| 1.2 | 9.2 | GO:0046618 | drug export(GO:0046618) |
| 1.1 | 3.4 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 1.1 | 16.7 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 1.1 | 4.4 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 1.1 | 3.3 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 1.1 | 13.0 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 1.1 | 74.1 | GO:0007098 | centrosome cycle(GO:0007098) |
| 1.0 | 19.8 | GO:0050892 | intestinal absorption(GO:0050892) |
| 1.0 | 6.1 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 1.0 | 1.0 | GO:2000696 | regulation of epithelial cell differentiation involved in kidney development(GO:2000696) |
| 1.0 | 1.0 | GO:0060648 | mammary gland bud morphogenesis(GO:0060648) |
| 1.0 | 8.7 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.9 | 2.8 | GO:0002353 | kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) |
| 0.9 | 28.0 | GO:0006582 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
| 0.9 | 7.4 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.9 | 11.1 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.9 | 15.4 | GO:0014904 | myotube cell development(GO:0014904) |
| 0.9 | 14.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.9 | 3.6 | GO:1901838 | regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.9 | 0.9 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
| 0.9 | 21.4 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.9 | 3.5 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 0.9 | 1.7 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 0.9 | 43.1 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
| 0.8 | 41.6 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.8 | 8.2 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.8 | 2.4 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.8 | 6.4 | GO:0002441 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.8 | 47.0 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.8 | 11.9 | GO:0031424 | keratinization(GO:0031424) |
| 0.8 | 3.2 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 0.8 | 7.1 | GO:0006568 | tryptophan metabolic process(GO:0006568) |
| 0.8 | 1.5 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
| 0.7 | 6.0 | GO:0006787 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.7 | 7.4 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.7 | 96.9 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.7 | 2.2 | GO:0050894 | determination of affect(GO:0050894) |
| 0.7 | 13.2 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.7 | 11.0 | GO:0051569 | regulation of histone H3-K4 methylation(GO:0051569) |
| 0.7 | 3.6 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.7 | 9.2 | GO:0046686 | response to cadmium ion(GO:0046686) |
| 0.7 | 6.4 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.7 | 6.2 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.7 | 8.3 | GO:1901687 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.7 | 2.7 | GO:0060671 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.7 | 4.0 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.7 | 5.3 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.6 | 82.3 | GO:0071466 | cellular response to xenobiotic stimulus(GO:0071466) |
| 0.6 | 29.4 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.6 | 9.2 | GO:0006959 | humoral immune response(GO:0006959) |
| 0.6 | 1.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.6 | 1.2 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.6 | 3.5 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
| 0.6 | 9.9 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.6 | 20.5 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.6 | 4.5 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.6 | 5.6 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.6 | 1.7 | GO:0002703 | regulation of leukocyte mediated immunity(GO:0002703) |
| 0.6 | 4.4 | GO:0030100 | regulation of endocytosis(GO:0030100) |
| 0.5 | 1.6 | GO:1901162 | isoquinoline alkaloid metabolic process(GO:0033076) serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314) primary amino compound biosynthetic process(GO:1901162) |
| 0.5 | 21.1 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.5 | 1.6 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.5 | 17.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.5 | 1.6 | GO:0032785 | negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.5 | 74.5 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.5 | 1.0 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.5 | 37.7 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.5 | 3.0 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.5 | 12.6 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.5 | 1.5 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 0.5 | 3.3 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.5 | 4.6 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.5 | 23.9 | GO:0051452 | pH reduction(GO:0045851) intracellular pH reduction(GO:0051452) |
| 0.5 | 2.7 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.4 | 6.7 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
| 0.4 | 2.7 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.4 | 0.9 | GO:0021558 | trochlear nerve development(GO:0021558) |
| 0.4 | 2.2 | GO:0090181 | regulation of cholesterol metabolic process(GO:0090181) |
| 0.4 | 3.4 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.4 | 0.8 | GO:1902994 | regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) |
| 0.4 | 8.8 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.4 | 2.7 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.4 | 0.8 | GO:0032304 | negative regulation of icosanoid secretion(GO:0032304) |
| 0.4 | 0.4 | GO:0002580 | regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) |
| 0.4 | 47.1 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.4 | 17.2 | GO:0071357 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.4 | 41.2 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.4 | 1.4 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.4 | 2.5 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.3 | 20.6 | GO:0042035 | regulation of cytokine biosynthetic process(GO:0042035) |
| 0.3 | 5.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.3 | 2.7 | GO:1904776 | protein localization to cell cortex(GO:0072697) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.3 | 2.0 | GO:0060135 | maternal process involved in female pregnancy(GO:0060135) |
| 0.3 | 5.0 | GO:1990542 | mitochondrial transmembrane transport(GO:1990542) |
| 0.3 | 1.7 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.3 | 1.0 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.3 | 2.6 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.3 | 1.6 | GO:0009650 | UV protection(GO:0009650) |
| 0.3 | 2.8 | GO:0007517 | muscle organ development(GO:0007517) muscle structure development(GO:0061061) |
| 0.3 | 2.1 | GO:0048069 | eye pigmentation(GO:0048069) |
| 0.3 | 1.2 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.3 | 4.1 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.3 | 12.0 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.3 | 3.4 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.3 | 1.1 | GO:0010626 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.3 | 1.9 | GO:1903204 | negative regulation of oxidative stress-induced neuron death(GO:1903204) |
| 0.3 | 3.6 | GO:0031664 | regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664) |
| 0.3 | 4.6 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.3 | 2.4 | GO:0051923 | sulfation(GO:0051923) |
| 0.3 | 1.8 | GO:1990564 | protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.2 | 2.2 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 4.8 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.2 | 1.1 | GO:1900016 | negative regulation of cytokine production involved in inflammatory response(GO:1900016) |
| 0.2 | 0.9 | GO:0048702 | embryonic neurocranium morphogenesis(GO:0048702) |
| 0.2 | 2.7 | GO:0030728 | ovulation(GO:0030728) |
| 0.2 | 1.6 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.2 | 2.8 | GO:0009128 | purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) |
| 0.2 | 1.7 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.2 | 0.9 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.2 | 0.2 | GO:0003166 | bundle of His development(GO:0003166) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926) |
| 0.2 | 1.2 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.2 | 1.0 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.2 | 2.3 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.2 | 3.6 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.2 | 0.2 | GO:1902805 | positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle exocytosis(GO:2000302) |
| 0.2 | 3.8 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.2 | 1.4 | GO:0046051 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 0.2 | 0.6 | GO:2001286 | regulation of caveolin-mediated endocytosis(GO:2001286) positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 0.6 | GO:0060346 | bone trabecula formation(GO:0060346) |
| 0.1 | 1.3 | GO:0031282 | regulation of guanylate cyclase activity(GO:0031282) |
| 0.1 | 1.0 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.1 | 2.7 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.1 | 1.0 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.1 | 0.2 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.1 | 0.6 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.1 | 3.0 | GO:0045745 | positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745) |
| 0.1 | 0.7 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.1 | 0.7 | GO:0030091 | protein repair(GO:0030091) |
| 0.1 | 0.3 | GO:0006636 | unsaturated fatty acid biosynthetic process(GO:0006636) |
| 0.1 | 0.3 | GO:0001820 | serotonin secretion(GO:0001820) regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063) |
| 0.1 | 1.0 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.1 | 0.6 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.1 | 0.3 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.1 | 0.7 | GO:0090102 | cochlea development(GO:0090102) |
| 0.1 | 0.4 | GO:0030210 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.1 | 0.7 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 0.6 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 1.0 | GO:0051931 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
| 0.0 | 0.3 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 1.4 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
| 0.0 | 0.7 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.6 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.2 | GO:0030238 | male sex determination(GO:0030238) |
| 0.0 | 0.2 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.0 | 0.1 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
| 0.0 | 0.1 | GO:0032930 | positive regulation of superoxide anion generation(GO:0032930) |
| 0.0 | 1.1 | GO:0051341 | regulation of oxidoreductase activity(GO:0051341) |
| 0.0 | 2.3 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 0.4 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.0 | 0.5 | GO:0030101 | natural killer cell activation(GO:0030101) |
| 0.0 | 0.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 125.0 | 625.2 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 109.7 | 329.1 | GO:1990298 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 101.7 | 508.3 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 96.3 | 289.0 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 67.1 | 268.2 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 66.2 | 198.7 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 61.3 | 490.1 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 52.7 | 158.0 | GO:0005715 | late recombination nodule(GO:0005715) |
| 46.1 | 138.3 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 44.6 | 133.7 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 42.1 | 126.2 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 41.7 | 166.6 | GO:0031211 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 40.8 | 163.2 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 39.8 | 1194.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 38.7 | 154.9 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 32.6 | 130.5 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 30.4 | 639.1 | GO:0000812 | Swr1 complex(GO:0000812) |
| 29.5 | 235.9 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 29.2 | 87.7 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 29.1 | 494.4 | GO:0034709 | methylosome(GO:0034709) |
| 28.6 | 85.7 | GO:0097124 | cyclin A2-CDK2 complex(GO:0097124) |
| 27.9 | 195.0 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 26.7 | 320.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 26.6 | 26.6 | GO:0005687 | U4 snRNP(GO:0005687) |
| 26.6 | 345.2 | GO:0042555 | MCM complex(GO:0042555) |
| 26.2 | 104.6 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 25.7 | 179.7 | GO:0061617 | MICOS complex(GO:0061617) |
| 23.8 | 190.5 | GO:0042382 | paraspeckles(GO:0042382) |
| 23.1 | 322.9 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 22.9 | 389.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 22.5 | 45.0 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 22.2 | 155.6 | GO:0016272 | prefoldin complex(GO:0016272) |
| 21.4 | 64.1 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 20.5 | 143.6 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 19.6 | 137.4 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 18.3 | 292.2 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 18.3 | 73.0 | GO:0070876 | SOSS complex(GO:0070876) |
| 17.9 | 196.9 | GO:0005688 | U6 snRNP(GO:0005688) |
| 17.3 | 69.2 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 17.3 | 69.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 16.7 | 200.1 | GO:0005642 | annulate lamellae(GO:0005642) |
| 16.5 | 923.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 16.3 | 81.4 | GO:1905202 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 16.3 | 97.6 | GO:0001740 | Barr body(GO:0001740) |
| 16.0 | 63.9 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 15.8 | 31.5 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 15.7 | 47.1 | GO:0097447 | dendritic tree(GO:0097447) |
| 14.8 | 74.1 | GO:0000235 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 14.4 | 43.2 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 14.1 | 155.0 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 13.8 | 290.6 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 13.7 | 164.1 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 13.6 | 54.5 | GO:0000811 | GINS complex(GO:0000811) |
| 13.5 | 81.1 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 13.5 | 54.0 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 12.6 | 301.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 12.5 | 112.4 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 12.4 | 123.6 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 12.4 | 61.8 | GO:0033503 | HULC complex(GO:0033503) |
| 12.2 | 73.5 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 12.0 | 59.8 | GO:0097422 | tubular endosome(GO:0097422) |
| 11.6 | 58.0 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 11.4 | 22.8 | GO:1903349 | omegasome membrane(GO:1903349) |
| 11.3 | 90.3 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 11.1 | 44.3 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 11.1 | 33.2 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 10.9 | 76.2 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 9.8 | 39.1 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 9.7 | 174.7 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 9.6 | 28.7 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 9.2 | 110.0 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 8.3 | 24.9 | GO:0030904 | retromer complex(GO:0030904) |
| 8.1 | 56.7 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 8.0 | 80.1 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 7.8 | 86.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 7.8 | 405.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 7.8 | 46.5 | GO:0071817 | MMXD complex(GO:0071817) |
| 7.8 | 147.3 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 7.5 | 37.7 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 7.4 | 44.6 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 7.4 | 88.4 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 7.2 | 14.5 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 7.1 | 163.3 | GO:0005685 | U1 snRNP(GO:0005685) |
| 7.0 | 77.3 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 6.7 | 13.5 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 6.5 | 26.2 | GO:0035061 | interchromatin granule(GO:0035061) |
| 6.5 | 45.5 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 6.5 | 38.9 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 6.4 | 121.4 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 6.2 | 99.6 | GO:0005814 | centriole(GO:0005814) |
| 6.2 | 56.0 | GO:0071439 | clathrin complex(GO:0071439) |
| 6.2 | 93.0 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 6.1 | 354.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 6.1 | 24.3 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 5.9 | 29.6 | GO:0005869 | dynactin complex(GO:0005869) |
| 5.8 | 122.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 5.8 | 34.6 | GO:1990635 | proximal dendrite(GO:1990635) |
| 5.5 | 72.1 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 5.5 | 11.1 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 5.5 | 16.6 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 5.5 | 54.9 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 5.4 | 81.4 | GO:0005916 | fascia adherens(GO:0005916) |
| 5.3 | 73.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 5.2 | 183.4 | GO:0005876 | spindle microtubule(GO:0005876) |
| 5.2 | 125.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 5.2 | 26.1 | GO:0032449 | CBM complex(GO:0032449) lipopolysaccharide receptor complex(GO:0046696) |
| 5.2 | 36.4 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 5.0 | 60.6 | GO:0090543 | Flemming body(GO:0090543) |
| 5.0 | 54.5 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 5.0 | 168.3 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 4.9 | 138.3 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 4.9 | 9.8 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 4.8 | 28.8 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 4.7 | 236.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 4.7 | 14.0 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 4.6 | 23.2 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 4.5 | 31.4 | GO:0071203 | WASH complex(GO:0071203) |
| 4.4 | 71.0 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 4.4 | 22.1 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 4.3 | 282.9 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 4.3 | 21.4 | GO:0031226 | intrinsic component of plasma membrane(GO:0031226) |
| 4.2 | 58.9 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 4.2 | 58.7 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 4.1 | 28.5 | GO:1990391 | DNA repair complex(GO:1990391) |
| 4.0 | 32.3 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 4.0 | 48.1 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 3.9 | 27.6 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 3.9 | 74.2 | GO:0001891 | phagocytic cup(GO:0001891) |
| 3.8 | 376.4 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 3.8 | 280.3 | GO:0035580 | specific granule lumen(GO:0035580) |
| 3.8 | 61.3 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 3.8 | 26.3 | GO:0031415 | NatA complex(GO:0031415) |
| 3.7 | 7.4 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 3.7 | 32.9 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 3.6 | 3.6 | GO:1990462 | omegasome(GO:1990462) |
| 3.6 | 32.1 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 3.6 | 35.6 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 3.5 | 179.2 | GO:0000786 | nucleosome(GO:0000786) |
| 3.4 | 20.4 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 3.4 | 272.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 3.3 | 73.3 | GO:0000776 | kinetochore(GO:0000776) |
| 3.3 | 66.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 3.3 | 69.2 | GO:1902555 | endoribonuclease complex(GO:1902555) |
| 3.3 | 16.3 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 3.3 | 16.3 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 3.2 | 38.9 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 3.2 | 50.6 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 3.2 | 79.0 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 3.1 | 12.4 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 3.1 | 9.3 | GO:0031515 | tRNA (m1A) methyltransferase complex(GO:0031515) |
| 3.1 | 449.0 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 3.1 | 268.9 | GO:0005643 | nuclear pore(GO:0005643) |
| 2.9 | 11.6 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 2.9 | 11.5 | GO:0070545 | PeBoW complex(GO:0070545) |
| 2.8 | 25.1 | GO:0043203 | axon hillock(GO:0043203) |
| 2.8 | 8.3 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 2.7 | 38.4 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 2.7 | 21.8 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 2.7 | 8.2 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 2.7 | 18.8 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 2.6 | 7.9 | GO:0031166 | integral component of vacuolar membrane(GO:0031166) |
| 2.6 | 52.6 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 2.6 | 93.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 2.5 | 22.9 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 2.5 | 22.5 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 2.5 | 12.5 | GO:0070826 | paraferritin complex(GO:0070826) |
| 2.5 | 54.9 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 2.5 | 17.4 | GO:0016600 | flotillin complex(GO:0016600) |
| 2.5 | 12.4 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 2.5 | 166.2 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 2.5 | 19.8 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 2.5 | 24.5 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 2.4 | 64.8 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 2.4 | 391.3 | GO:0000793 | condensed chromosome(GO:0000793) |
| 2.3 | 44.3 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 2.3 | 34.7 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
| 2.3 | 20.7 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 2.3 | 4.6 | GO:0034657 | GID complex(GO:0034657) |
| 2.3 | 61.3 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 2.2 | 84.7 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 2.2 | 171.7 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 2.1 | 33.3 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 2.1 | 8.3 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 2.1 | 10.3 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 2.0 | 14.2 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 1.9 | 149.1 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 1.9 | 40.1 | GO:0032040 | small-subunit processome(GO:0032040) |
| 1.9 | 35.6 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 1.9 | 14.9 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 1.8 | 9.1 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 1.8 | 16.0 | GO:0005955 | calcineurin complex(GO:0005955) |
| 1.7 | 17.1 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 1.7 | 35.5 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 1.6 | 7.9 | GO:0030894 | replisome(GO:0030894) |
| 1.6 | 6.3 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 1.5 | 166.9 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 1.4 | 20.2 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 1.4 | 4.3 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 1.4 | 12.9 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 1.4 | 17.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 1.4 | 184.9 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 1.4 | 15.6 | GO:0051233 | spindle midzone(GO:0051233) |
| 1.4 | 50.8 | GO:0016592 | mediator complex(GO:0016592) |
| 1.4 | 12.6 | GO:0034464 | BBSome(GO:0034464) |
| 1.4 | 147.8 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 1.3 | 239.4 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 1.3 | 18.4 | GO:0031519 | PcG protein complex(GO:0031519) |
| 1.3 | 9.1 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 1.3 | 18.1 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 1.3 | 304.8 | GO:0005694 | chromosome(GO:0005694) |
| 1.3 | 47.8 | GO:0030496 | midbody(GO:0030496) |
| 1.2 | 418.5 | GO:0005635 | nuclear envelope(GO:0005635) |
| 1.2 | 4.7 | GO:0043073 | germ cell nucleus(GO:0043073) |
| 1.1 | 8.0 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 1.1 | 12.0 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 1.1 | 110.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 1.0 | 10.8 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.9 | 28.9 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.9 | 46.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.9 | 3.7 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.9 | 2.7 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 0.9 | 9.1 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.8 | 51.0 | GO:0005902 | microvillus(GO:0005902) |
| 0.8 | 2.5 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 0.8 | 29.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.8 | 9.1 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.8 | 42.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.7 | 87.7 | GO:0034774 | secretory granule lumen(GO:0034774) |
| 0.7 | 14.5 | GO:0016459 | myosin complex(GO:0016459) |
| 0.7 | 49.0 | GO:0000922 | spindle pole(GO:0000922) |
| 0.7 | 75.4 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.7 | 11.1 | GO:0000145 | exocyst(GO:0000145) |
| 0.7 | 52.6 | GO:0016605 | PML body(GO:0016605) |
| 0.7 | 10.0 | GO:0032059 | bleb(GO:0032059) |
| 0.7 | 26.0 | GO:0045095 | keratin filament(GO:0045095) |
| 0.6 | 74.4 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.6 | 12.8 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.6 | 6.7 | GO:0005929 | cilium(GO:0005929) |
| 0.6 | 21.6 | GO:0015030 | Cajal body(GO:0015030) |
| 0.6 | 1.1 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.6 | 150.0 | GO:0019866 | mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866) |
| 0.5 | 45.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.5 | 3.2 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.5 | 23.8 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.5 | 11.0 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.5 | 4.4 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.5 | 2.3 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.4 | 1.8 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.4 | 38.0 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
| 0.4 | 2.2 | GO:0032021 | NELF complex(GO:0032021) |
| 0.4 | 2.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.4 | 3.4 | GO:0070187 | telosome(GO:0070187) |
| 0.4 | 2.2 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
| 0.4 | 3.3 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 0.4 | 9.2 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.3 | 3.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.3 | 0.6 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 0.3 | 1.2 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.3 | 7.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.3 | 75.2 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.3 | 1.1 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.3 | 1.0 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.3 | 2.6 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.3 | 1.0 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.2 | 4.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.2 | 1.2 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.2 | 0.8 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.2 | 0.7 | GO:0030684 | preribosome(GO:0030684) |
| 0.2 | 22.6 | GO:0005874 | microtubule(GO:0005874) |
| 0.2 | 2.2 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.2 | 10.1 | GO:0043292 | contractile fiber(GO:0043292) |
| 0.2 | 9.0 | GO:0030315 | T-tubule(GO:0030315) |
| 0.1 | 5.2 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 65.7 | GO:0042175 | nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175) |
| 0.1 | 0.9 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 1.0 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 3.8 | GO:0044439 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
| 0.1 | 5.7 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.1 | 2.2 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 2.2 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 19.0 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 238.2 | GO:0005829 | cytosol(GO:0005829) |
| 0.1 | 1.1 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 1.4 | GO:0072562 | blood microparticle(GO:0072562) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 175.5 | 1228.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 96.4 | 385.5 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 96.3 | 289.0 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 67.1 | 268.2 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 61.8 | 309.1 | GO:0032139 | dinucleotide insertion or deletion binding(GO:0032139) |
| 55.0 | 330.3 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 52.5 | 209.8 | GO:0004310 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 50.2 | 301.3 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 48.5 | 436.5 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 46.7 | 140.1 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 43.6 | 130.8 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 42.2 | 210.9 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 38.0 | 228.1 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 35.3 | 176.7 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 34.1 | 102.2 | GO:0004487 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 33.4 | 133.7 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 33.0 | 165.1 | GO:0004161 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 32.9 | 32.9 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 32.0 | 320.3 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 31.0 | 340.7 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 29.6 | 88.7 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 29.1 | 116.3 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 27.6 | 82.9 | GO:0097158 | pre-mRNA intronic pyrimidine-rich binding(GO:0097158) |
| 24.8 | 248.5 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 24.3 | 73.0 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 23.6 | 70.9 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 23.0 | 298.4 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 22.9 | 68.8 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 21.8 | 65.5 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 21.3 | 63.8 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
| 19.2 | 76.9 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 18.9 | 869.3 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 18.3 | 329.8 | GO:0035173 | histone kinase activity(GO:0035173) |
| 18.3 | 146.2 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 18.1 | 72.5 | GO:0016936 | galactoside binding(GO:0016936) |
| 18.1 | 36.3 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 18.1 | 90.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 17.5 | 87.7 | GO:0019798 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 17.3 | 52.0 | GO:0004819 | glutamine-tRNA ligase activity(GO:0004819) |
| 17.3 | 776.3 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 16.6 | 49.9 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 16.6 | 66.2 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 16.3 | 81.4 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 15.1 | 256.4 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 15.0 | 556.4 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 15.0 | 74.8 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 14.9 | 29.8 | GO:0030984 | kininogen binding(GO:0030984) |
| 14.6 | 644.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 13.9 | 69.3 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 13.6 | 40.9 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 13.6 | 54.5 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 13.6 | 27.1 | GO:0046979 | TAP2 binding(GO:0046979) |
| 13.5 | 135.4 | GO:0042731 | PH domain binding(GO:0042731) |
| 13.5 | 81.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 13.4 | 40.2 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 13.1 | 52.4 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 13.1 | 65.5 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 12.9 | 142.1 | GO:0015266 | protein channel activity(GO:0015266) |
| 12.8 | 140.3 | GO:0046790 | virion binding(GO:0046790) |
| 12.7 | 38.1 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 12.1 | 36.4 | GO:0001002 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
| 11.9 | 47.6 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 11.9 | 35.7 | GO:0031859 | platelet activating factor receptor binding(GO:0031859) |
| 11.5 | 69.2 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 11.3 | 135.6 | GO:0031386 | protein tag(GO:0031386) |
| 11.3 | 135.5 | GO:0046972 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 11.1 | 55.3 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 11.0 | 33.0 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 10.9 | 43.5 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 10.9 | 65.2 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 10.8 | 97.3 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 10.8 | 32.4 | GO:0070538 | oleic acid binding(GO:0070538) |
| 10.7 | 42.8 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 10.6 | 31.9 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 10.6 | 10.6 | GO:0070404 | NADH binding(GO:0070404) |
| 10.6 | 31.7 | GO:0048030 | disaccharide binding(GO:0048030) |
| 10.5 | 73.5 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 10.5 | 41.9 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 10.3 | 51.7 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 10.3 | 71.9 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 10.2 | 194.6 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 10.0 | 50.0 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 10.0 | 39.8 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 9.9 | 89.5 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 9.9 | 29.7 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 9.9 | 49.4 | GO:0004359 | glutaminase activity(GO:0004359) |
| 9.7 | 77.7 | GO:0004396 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 9.5 | 293.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 9.5 | 37.8 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 9.3 | 204.0 | GO:0070402 | NADPH binding(GO:0070402) |
| 9.1 | 127.7 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 9.0 | 315.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 9.0 | 63.0 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 8.9 | 17.8 | GO:0061650 | ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 8.8 | 26.3 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
| 8.6 | 69.1 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 8.6 | 34.5 | GO:0052795 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 8.6 | 77.1 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 8.4 | 25.3 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 8.3 | 191.5 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 8.3 | 33.1 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 8.1 | 32.4 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 7.8 | 23.5 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 7.8 | 39.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 7.8 | 46.9 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 7.7 | 46.3 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 7.6 | 53.4 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 7.6 | 259.5 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 7.5 | 44.7 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 7.2 | 28.7 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 7.1 | 276.4 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 7.0 | 21.0 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 7.0 | 208.7 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 6.9 | 132.0 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 6.9 | 34.7 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 6.8 | 27.2 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 6.8 | 81.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 6.7 | 67.2 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 6.7 | 33.6 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
| 6.6 | 359.1 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 6.6 | 124.8 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 6.5 | 38.9 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 6.3 | 132.1 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 6.3 | 100.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 6.3 | 31.3 | GO:0008483 | transaminase activity(GO:0008483) |
| 6.2 | 24.8 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
| 6.2 | 31.0 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 6.2 | 18.6 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 6.2 | 148.3 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 6.2 | 86.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 6.1 | 24.5 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 6.0 | 23.9 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 5.9 | 35.5 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 5.8 | 63.4 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 5.7 | 17.2 | GO:0048039 | quinone binding(GO:0048038) ubiquinone binding(GO:0048039) |
| 5.5 | 22.2 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 5.5 | 49.9 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 5.5 | 44.3 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 5.5 | 5.5 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 5.5 | 307.6 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 5.4 | 308.7 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
| 5.4 | 21.5 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 5.3 | 26.6 | GO:0070990 | snRNP binding(GO:0070990) |
| 5.3 | 63.4 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 5.2 | 57.4 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 5.2 | 281.5 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 5.2 | 26.0 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 5.2 | 41.4 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 5.2 | 242.8 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 5.1 | 15.3 | GO:0044549 | GTP cyclohydrolase binding(GO:0044549) |
| 5.0 | 139.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 4.9 | 24.3 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 4.8 | 33.8 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 4.8 | 23.8 | GO:0070905 | serine binding(GO:0070905) |
| 4.7 | 14.0 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 4.6 | 59.7 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 4.6 | 13.7 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 4.5 | 139.9 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 4.4 | 13.3 | GO:0016781 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 4.4 | 44.1 | GO:0016829 | lyase activity(GO:0016829) |
| 4.4 | 158.8 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 4.4 | 52.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 4.4 | 69.9 | GO:0031491 | nucleosome binding(GO:0031491) |
| 4.3 | 25.7 | GO:0031543 | peptidyl-proline dioxygenase activity(GO:0031543) |
| 4.3 | 12.8 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 4.3 | 63.8 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 4.2 | 4.2 | GO:0008413 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539) |
| 4.2 | 25.3 | GO:0034452 | dynactin binding(GO:0034452) |
| 4.2 | 8.3 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 4.0 | 20.0 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 4.0 | 95.8 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 4.0 | 16.0 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 4.0 | 79.6 | GO:0000339 | RNA cap binding(GO:0000339) |
| 4.0 | 19.8 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 4.0 | 39.6 | GO:0055104 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 3.9 | 78.9 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 3.9 | 50.6 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 3.9 | 66.1 | GO:0005537 | mannose binding(GO:0005537) |
| 3.9 | 147.3 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 3.9 | 46.5 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 3.8 | 38.4 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 3.8 | 11.4 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 3.8 | 15.1 | GO:0005471 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 3.7 | 82.4 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 3.7 | 130.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 3.7 | 40.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 3.7 | 410.0 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 3.6 | 101.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 3.6 | 28.9 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
| 3.6 | 3.6 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 3.6 | 21.4 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 3.5 | 10.4 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 3.5 | 48.5 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
| 3.4 | 79.0 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 3.4 | 133.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 3.4 | 50.8 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 3.4 | 27.0 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 3.3 | 26.8 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 3.3 | 6.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 3.3 | 62.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 3.3 | 291.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 3.2 | 25.8 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 3.2 | 15.8 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 3.1 | 6.2 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 3.1 | 40.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 3.1 | 9.3 | GO:0016426 | tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429) |
| 3.1 | 49.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 3.1 | 15.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 3.0 | 18.1 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 3.0 | 30.0 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 3.0 | 17.9 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 2.9 | 26.1 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 2.9 | 214.7 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 2.8 | 8.5 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 2.8 | 16.9 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 2.8 | 14.1 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 2.8 | 24.9 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 2.8 | 19.3 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 2.7 | 8.2 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 2.7 | 10.9 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 2.7 | 16.3 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673) |
| 2.7 | 43.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 2.7 | 24.0 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 2.6 | 31.6 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 2.6 | 10.5 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 2.6 | 15.5 | GO:0008948 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948) |
| 2.5 | 35.5 | GO:0070628 | proteasome binding(GO:0070628) |
| 2.5 | 10.0 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 2.5 | 7.4 | GO:0033867 | Fas-activated serine/threonine kinase activity(GO:0033867) |
| 2.5 | 12.3 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 2.4 | 44.0 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 2.4 | 12.1 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 2.4 | 33.9 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 2.4 | 58.9 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 2.3 | 7.0 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 2.3 | 11.6 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 2.3 | 18.5 | GO:0089720 | caspase binding(GO:0089720) |
| 2.3 | 13.9 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 2.3 | 6.9 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 2.3 | 139.5 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 2.3 | 6.8 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 2.2 | 40.1 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 2.2 | 17.7 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 2.2 | 109.2 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 2.1 | 131.0 | GO:0005507 | copper ion binding(GO:0005507) |
| 2.1 | 42.8 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 2.1 | 2.1 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 2.1 | 173.2 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 2.1 | 36.0 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 2.1 | 6.3 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 2.1 | 195.9 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 2.1 | 115.6 | GO:0002039 | p53 binding(GO:0002039) |
| 2.1 | 65.9 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 2.1 | 16.5 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 2.1 | 22.6 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 2.0 | 409.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 2.0 | 8.2 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 2.0 | 48.4 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 1.9 | 27.2 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 1.9 | 23.2 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
| 1.9 | 3.8 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 1.9 | 7.6 | GO:0033265 | choline binding(GO:0033265) |
| 1.9 | 56.0 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 1.9 | 9.3 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 1.8 | 9.2 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 1.8 | 11.0 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 1.8 | 23.8 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 1.8 | 51.2 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 1.8 | 5.3 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 1.7 | 13.9 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 1.7 | 5.2 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 1.7 | 10.3 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 1.7 | 8.6 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
| 1.7 | 61.8 | GO:0043531 | ADP binding(GO:0043531) |
| 1.7 | 17.1 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 1.7 | 22.0 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 1.7 | 25.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 1.7 | 35.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 1.7 | 33.6 | GO:0004549 | tRNA-specific ribonuclease activity(GO:0004549) |
| 1.7 | 38.0 | GO:0031489 | myosin V binding(GO:0031489) |
| 1.6 | 75.4 | GO:0016859 | cis-trans isomerase activity(GO:0016859) |
| 1.6 | 34.0 | GO:0019894 | kinesin binding(GO:0019894) |
| 1.6 | 4.8 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 1.6 | 191.5 | GO:0042393 | histone binding(GO:0042393) |
| 1.6 | 6.4 | GO:0015563 | uptake transmembrane transporter activity(GO:0015563) |
| 1.6 | 9.5 | GO:0050733 | RS domain binding(GO:0050733) |
| 1.6 | 18.8 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 1.5 | 9.1 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 1.5 | 58.5 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 1.5 | 26.8 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 1.5 | 3.0 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 1.5 | 11.7 | GO:0050072 | m7G(5')pppN diphosphatase activity(GO:0050072) |
| 1.5 | 17.5 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 1.5 | 11.6 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 1.4 | 37.5 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
| 1.4 | 4.3 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 1.4 | 9.9 | GO:0008199 | ferric iron binding(GO:0008199) |
| 1.4 | 15.5 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 1.4 | 5.5 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 1.4 | 458.9 | GO:0045296 | cadherin binding(GO:0045296) |
| 1.3 | 18.6 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 1.3 | 3.9 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 1.3 | 97.9 | GO:0004386 | helicase activity(GO:0004386) |
| 1.3 | 5.0 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 1.2 | 185.6 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 1.2 | 95.3 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 1.2 | 7.3 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 1.2 | 23.1 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 1.2 | 4.8 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 1.2 | 23.9 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
| 1.2 | 11.8 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 1.2 | 11.5 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 1.1 | 4.5 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 1.1 | 19.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 1.1 | 3.4 | GO:1904047 | cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) S-adenosyl-L-methionine binding(GO:1904047) |
| 1.1 | 11.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 1.1 | 4.4 | GO:0004335 | galactokinase activity(GO:0004335) |
| 1.1 | 8.6 | GO:0032182 | ubiquitin-like protein binding(GO:0032182) |
| 1.1 | 7.4 | GO:0008312 | 7S RNA binding(GO:0008312) |
| 1.0 | 41.4 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 1.0 | 2.1 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 1.0 | 6.1 | GO:0004521 | endoribonuclease activity(GO:0004521) |
| 1.0 | 13.1 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 1.0 | 33.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.9 | 3.8 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
| 0.9 | 1.9 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.9 | 13.0 | GO:0052744 | phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744) |
| 0.9 | 41.9 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.9 | 11.0 | GO:0004659 | prenyltransferase activity(GO:0004659) |
| 0.9 | 27.3 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.9 | 34.6 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.9 | 836.9 | GO:0003723 | RNA binding(GO:0003723) |
| 0.9 | 92.0 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.9 | 31.8 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.9 | 12.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.8 | 12.4 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.8 | 2.4 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.8 | 2.4 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.8 | 3.9 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.7 | 5.2 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.7 | 4.5 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.7 | 2.2 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.7 | 1.5 | GO:0000035 | acyl binding(GO:0000035) |
| 0.7 | 9.4 | GO:0071949 | FAD binding(GO:0071949) |
| 0.7 | 2.9 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.7 | 3.6 | GO:0038187 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.7 | 3.5 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.7 | 3.3 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 0.7 | 4.6 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.7 | 2.7 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.6 | 6.9 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.6 | 9.2 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.6 | 7.8 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.6 | 1.8 | GO:0005254 | chloride channel activity(GO:0005254) chloride transmembrane transporter activity(GO:0015108) |
| 0.6 | 5.1 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.6 | 9.1 | GO:0015923 | alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923) |
| 0.6 | 5.0 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.5 | 4.2 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.5 | 16.9 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.5 | 1.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.5 | 1.0 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.5 | 11.6 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.5 | 7.0 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.5 | 2.0 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.5 | 3.3 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.5 | 4.6 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.5 | 4.6 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.4 | 2.2 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.4 | 6.5 | GO:0016209 | antioxidant activity(GO:0016209) |
| 0.4 | 2.2 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.4 | 20.5 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.4 | 1.7 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.4 | 0.8 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.4 | 0.8 | GO:0008252 | nucleotidase activity(GO:0008252) |
| 0.4 | 0.8 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.4 | 5.5 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.4 | 5.4 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.4 | 28.1 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.4 | 31.5 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.4 | 1.5 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.4 | 1.1 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 0.4 | 1.4 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 0.3 | 0.3 | GO:0015925 | galactosidase activity(GO:0015925) |
| 0.3 | 1.6 | GO:0008237 | metallopeptidase activity(GO:0008237) |
| 0.3 | 54.5 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) |
| 0.3 | 3.9 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.3 | 2.4 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.3 | 12.4 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.3 | 26.1 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 0.3 | 1.7 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.3 | 1.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.3 | 2.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.2 | 0.2 | GO:0016453 | C-acetyltransferase activity(GO:0016453) |
| 0.2 | 2.5 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.2 | 0.9 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.2 | 0.6 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.2 | 0.2 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
| 0.2 | 1.4 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.2 | 1.0 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.2 | 0.9 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.2 | 2.0 | GO:0031701 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.2 | 0.5 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.2 | 3.6 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.2 | 0.9 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 0.1 | 1.9 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.1 | 1.2 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
| 0.1 | 0.4 | GO:0010851 | cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249) |
| 0.1 | 0.7 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.1 | 0.6 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 0.9 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.1 | 1.4 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.1 | 0.6 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.1 | 4.9 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 1.8 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.1 | 2.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 2.0 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 0.3 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.1 | 0.9 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 0.6 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 0.6 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.1 | 0.6 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 2.7 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.0 | 0.9 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.0 | 1.9 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.0 | 0.1 | GO:0015556 | C4-dicarboxylate transmembrane transporter activity(GO:0015556) |
| 0.0 | 0.3 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.1 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.1 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.0 | 0.5 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.0 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.0 | 0.2 | GO:0019992 | diacylglycerol binding(GO:0019992) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 31.1 | 2116.0 | PID PLK1 PATHWAY | PLK1 signaling events |
| 24.0 | 1655.0 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 19.8 | 19.8 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 15.6 | 234.3 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 12.3 | 318.7 | PID BARD1 PATHWAY | BARD1 signaling events |
| 11.0 | 430.9 | PID MYC PATHWAY | C-MYC pathway |
| 10.0 | 449.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 9.8 | 402.2 | PID AURORA A PATHWAY | Aurora A signaling |
| 9.7 | 476.1 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 9.4 | 877.3 | PID E2F PATHWAY | E2F transcription factor network |
| 6.9 | 179.3 | PID ATR PATHWAY | ATR signaling pathway |
| 5.1 | 219.6 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 5.0 | 853.0 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 4.9 | 24.5 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 4.8 | 312.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 3.9 | 125.4 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 3.7 | 41.1 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 3.6 | 14.4 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 3.3 | 229.5 | PID P73PATHWAY | p73 transcription factor network |
| 3.3 | 192.9 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 3.2 | 22.2 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 3.0 | 30.0 | ST STAT3 PATHWAY | STAT3 Pathway |
| 3.0 | 77.5 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 2.8 | 121.8 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 2.7 | 128.7 | PID FOXO PATHWAY | FoxO family signaling |
| 2.7 | 69.3 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 2.5 | 53.1 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 2.5 | 32.5 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 2.5 | 235.2 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 2.5 | 72.2 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 2.2 | 140.6 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 2.2 | 138.1 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 2.1 | 177.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 2.0 | 36.0 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 1.9 | 102.4 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 1.8 | 23.0 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 1.7 | 36.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 1.6 | 75.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 1.6 | 54.5 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 1.6 | 98.4 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 1.4 | 32.0 | PID RHOA PATHWAY | RhoA signaling pathway |
| 1.4 | 20.8 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 1.3 | 17.5 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 1.2 | 14.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 1.2 | 20.9 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.9 | 42.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.9 | 29.9 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.9 | 14.0 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.8 | 23.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.8 | 0.8 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.8 | 42.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.8 | 14.6 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.7 | 46.2 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.7 | 16.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.7 | 21.5 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.7 | 14.7 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.6 | 23.4 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.6 | 10.6 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.5 | 23.1 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.5 | 22.0 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.5 | 23.9 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.4 | 12.1 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.4 | 7.3 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.4 | 6.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.4 | 6.5 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.3 | 3.4 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.3 | 6.8 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.3 | 2.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 3.9 | PID ATM PATHWAY | ATM pathway |
| 0.2 | 2.7 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.2 | 15.2 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.2 | 34.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 4.9 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 1.3 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 1.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.0 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 1.6 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 0.7 | PID BMP PATHWAY | BMP receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 89.2 | 624.1 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 50.1 | 50.1 | REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 49.0 | 1371.3 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 48.5 | 581.8 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 34.6 | 1074.0 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 32.9 | 32.9 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 32.7 | 523.3 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 29.2 | 583.8 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 25.8 | 541.6 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 21.6 | 560.9 | REACTOME KINESINS | Genes involved in Kinesins |
| 20.0 | 320.7 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 19.6 | 156.9 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 18.5 | 259.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 17.5 | 332.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 16.7 | 149.9 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 14.9 | 223.1 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 14.1 | 226.2 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 14.0 | 266.2 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 12.6 | 590.3 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 12.5 | 312.2 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 12.1 | 1092.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 11.9 | 94.9 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 11.8 | 423.0 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 11.4 | 159.0 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 11.2 | 547.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 10.6 | 413.5 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 9.4 | 93.9 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 8.9 | 106.9 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 8.8 | 202.3 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 8.6 | 232.3 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 8.5 | 59.4 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 8.4 | 596.6 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 8.3 | 99.1 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 8.0 | 136.5 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 7.6 | 1089.7 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 7.3 | 73.3 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 7.3 | 131.5 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 7.1 | 78.1 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 6.9 | 145.9 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 6.9 | 220.3 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 6.9 | 41.2 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 6.8 | 392.1 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 6.7 | 74.1 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 6.4 | 63.8 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 6.4 | 108.1 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 5.9 | 70.3 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 5.8 | 92.0 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 5.1 | 142.9 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 5.0 | 130.8 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 4.9 | 93.7 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 4.7 | 93.9 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 4.4 | 70.7 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 4.3 | 93.8 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 4.2 | 41.7 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 4.1 | 146.0 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 4.0 | 32.2 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 3.9 | 62.6 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 3.8 | 56.8 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 3.7 | 78.0 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 3.6 | 64.6 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 3.5 | 300.5 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 3.5 | 52.5 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 3.5 | 93.5 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 3.4 | 57.7 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 3.1 | 89.2 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 3.1 | 21.5 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 3.0 | 61.0 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 2.9 | 140.9 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 2.8 | 33.3 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 2.7 | 13.4 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 2.5 | 86.1 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 2.3 | 160.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 2.3 | 66.4 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 2.3 | 11.3 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 2.2 | 116.6 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 2.1 | 34.3 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 2.1 | 48.5 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 2.1 | 90.4 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 2.1 | 58.0 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 2.1 | 138.2 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 2.0 | 13.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 2.0 | 82.6 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 2.0 | 33.2 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 1.9 | 262.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 1.8 | 422.1 | REACTOME TRANSLATION | Genes involved in Translation |
| 1.8 | 49.3 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 1.7 | 39.9 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 1.6 | 27.0 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 1.6 | 50.8 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 1.6 | 12.4 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 1.5 | 30.6 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 1.4 | 8.3 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 1.4 | 17.9 | REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX | Genes involved in Formation of the HIV-1 Early Elongation Complex |
| 1.3 | 36.5 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 1.3 | 21.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 1.2 | 25.4 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 1.1 | 26.6 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 1.0 | 5.1 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 1.0 | 17.4 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.9 | 9.1 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.9 | 104.9 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.9 | 53.2 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.9 | 10.3 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.9 | 29.0 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.8 | 12.0 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.8 | 6.3 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.8 | 12.5 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.7 | 10.3 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.7 | 30.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.6 | 5.1 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.6 | 10.9 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.6 | 3.6 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.6 | 12.8 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.5 | 16.7 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.5 | 21.6 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 0.5 | 15.5 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.4 | 5.8 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.4 | 14.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.4 | 16.7 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.3 | 3.4 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.3 | 16.2 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.3 | 11.4 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.3 | 6.6 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.3 | 14.0 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.3 | 10.1 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.3 | 21.3 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.2 | 7.0 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.2 | 2.3 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.1 | 6.4 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 22.6 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |
| 0.1 | 11.5 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 1.6 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 1.2 | REACTOME GLOBAL GENOMIC NER GG NER | Genes involved in Global Genomic NER (GG-NER) |
| 0.1 | 1.5 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.1 | 1.9 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 0.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |