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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for YY1_YY2

Z-value: 2.34

Motif logo

Transcription factors associated with YY1_YY2

Gene Symbol Gene ID Gene Info
ENSG00000100811.6 YY1 transcription factor
ENSG00000230797.2 YY2 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
YY1hg19_v2_chr14_+_100705322_1007053600.531.9e-17Click!
YY2hg19_v2_chrX_+_21874105_21874105-0.472.2e-13Click!

Activity profile of YY1_YY2 motif

Sorted Z-values of YY1_YY2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_1303462 72.71 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chr14_-_69864993 67.50 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr19_-_13044494 67.02 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
phenylalanyl-tRNA synthetase, alpha subunit
chr16_-_87903079 52.70 ENST00000261622.4
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr14_-_23504337 45.49 ENST00000361611.6
proteasome (prosome, macropain) subunit, beta type, 5
chr14_-_23504087 44.06 ENST00000493471.2
ENST00000460922.2
proteasome (prosome, macropain) subunit, beta type, 5
chr14_-_23504432 43.50 ENST00000425762.2
proteasome (prosome, macropain) subunit, beta type, 5
chr13_-_37679803 42.93 ENST00000379800.3
casein kinase 1, alpha 1-like
chr1_-_149900122 41.22 ENST00000271628.8
splicing factor 3b, subunit 4, 49kDa
chr7_+_73097890 40.90 ENST00000265758.2
ENST00000423166.2
ENST00000423497.1
Williams Beuren syndrome chromosome region 22
chr3_-_149688896 39.35 ENST00000239940.7
profilin 2
chr2_+_27851863 38.71 ENST00000264718.3
ENST00000610189.1
GPN-loop GTPase 1
chr3_-_149688502 37.10 ENST00000481767.1
ENST00000475518.1
profilin 2
chr1_-_222885770 36.79 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr12_+_7079944 34.90 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr15_-_89010607 34.10 ENST00000312475.4
mitochondrial ribosomal protein L46
chr11_+_75110530 34.07 ENST00000531188.1
ENST00000530164.1
ENST00000422465.2
ENST00000278572.6
ENST00000534440.1
ENST00000527446.1
ENST00000526608.1
ENST00000527273.1
ENST00000524851.1
ribosomal protein S3
chr14_+_103801140 33.66 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
eukaryotic translation initiation factor 5
chr1_+_156756667 33.41 ENST00000526188.1
ENST00000454659.1
papillary renal cell carcinoma (translocation-associated)
chr3_-_149688655 33.30 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr1_-_153949751 33.20 ENST00000428469.1
jumping translocation breakpoint
chr12_+_56211703 32.96 ENST00000243045.5
ENST00000552672.1
ENST00000550836.1
ORM1-like 2 (S. cerevisiae)
chr1_+_46769303 32.87 ENST00000311672.5
ubiquinol-cytochrome c reductase hinge protein
chr14_+_78174414 32.71 ENST00000557342.1
ENST00000238688.5
ENST00000557623.1
ENST00000557431.1
ENST00000556831.1
ENST00000556375.1
ENST00000553981.1
SRA stem-loop interacting RNA binding protein
chr14_-_23398565 32.66 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
protein arginine methyltransferase 5
chr5_-_71616043 31.81 ENST00000508863.2
ENST00000522095.1
ENST00000513900.1
ENST00000515404.1
ENST00000457646.4
ENST00000261413.5
mitochondrial ribosomal protein S27
chr19_-_2456922 31.26 ENST00000582871.1
ENST00000325327.3
lamin B2
chr11_+_57480046 31.17 ENST00000378312.4
ENST00000278422.4
thioredoxin-related transmembrane protein 2
chr20_-_49547731 31.09 ENST00000396029.3
activity-dependent neuroprotector homeobox
chr11_-_122929699 30.70 ENST00000526686.1
heat shock 70kDa protein 8
chr7_-_6523688 30.49 ENST00000490996.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_-_66206260 30.39 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
mitochondrial ribosomal protein L11
chr1_-_161087802 30.30 ENST00000368010.3
prefoldin subunit 2
chr11_-_14380664 30.00 ENST00000545643.1
ENST00000256196.4
related RAS viral (r-ras) oncogene homolog 2
chr2_+_86426478 29.70 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
mitochondrial ribosomal protein L35
chr3_+_160117418 29.66 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
structural maintenance of chromosomes 4
chr2_-_190044480 29.09 ENST00000374866.3
collagen, type V, alpha 2
chr5_-_180670880 29.01 ENST00000511566.1
ENST00000511900.1
ENST00000504726.1
ENST00000512968.1
ENST00000376817.4
ENST00000513027.1
ENST00000503081.1
ENST00000456394.2
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr19_+_38865398 28.97 ENST00000585598.1
ENST00000602911.1
ENST00000592561.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr5_+_154320623 28.94 ENST00000523037.1
ENST00000265229.8
ENST00000439747.3
ENST00000522038.1
mitochondrial ribosomal protein L22
chr1_-_153950164 28.71 ENST00000271843.4
jumping translocation breakpoint
chr14_-_54908043 28.63 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr1_-_153950098 27.89 ENST00000356648.1
jumping translocation breakpoint
chr19_+_16178317 27.68 ENST00000344824.6
ENST00000538887.1
tropomyosin 4
chr3_+_160117087 27.39 ENST00000357388.3
structural maintenance of chromosomes 4
chrX_+_119005399 27.38 ENST00000371437.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
chr19_+_38865176 26.42 ENST00000215071.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr1_-_153950116 26.25 ENST00000368589.1
jumping translocation breakpoint
chr10_-_120938303 25.62 ENST00000356951.3
ENST00000298510.2
peroxiredoxin 3
chr11_+_74660278 25.55 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr1_+_166808692 25.37 ENST00000367876.4
pogo transposable element with KRAB domain
chr6_-_8102714 25.11 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr11_-_122930121 25.07 ENST00000524552.1
heat shock 70kDa protein 8
chrX_-_109561294 24.88 ENST00000372059.2
ENST00000262844.5
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr3_-_12705600 24.87 ENST00000542177.1
ENST00000442415.2
ENST00000251849.4
v-raf-1 murine leukemia viral oncogene homolog 1
chr5_+_52856456 24.76 ENST00000296684.5
ENST00000506765.1
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr12_+_98987369 24.76 ENST00000401722.3
ENST00000188376.5
ENST00000228318.3
ENST00000551917.1
ENST00000548046.1
ENST00000552981.1
ENST00000551265.1
ENST00000550695.1
ENST00000547534.1
ENST00000549338.1
ENST00000548847.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr3_+_197677379 24.74 ENST00000442341.1
ribosomal protein L35a
chr6_-_8102279 24.67 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr11_+_65686802 24.30 ENST00000376991.2
DR1-associated protein 1 (negative cofactor 2 alpha)
chr5_-_180671172 24.24 ENST00000512805.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr4_-_103747011 24.10 ENST00000350435.7
ubiquitin-conjugating enzyme E2D 3
chr3_-_123304017 23.98 ENST00000383657.5
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chr7_-_72936531 23.91 ENST00000339594.4
bromodomain adjacent to zinc finger domain, 1B
chr3_-_183966717 23.78 ENST00000446569.1
ENST00000418734.2
ENST00000397676.3
ALG3, alpha-1,3- mannosyltransferase
chrX_+_154444643 23.63 ENST00000286428.5
von Hippel-Lindau binding protein 1
chr9_-_127177703 23.58 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
proteasome (prosome, macropain) subunit, beta type, 7
chr7_-_6523755 23.41 ENST00000436575.1
ENST00000258739.4
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr12_+_12966250 23.39 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chrX_+_106871713 23.24 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
phosphoribosyl pyrophosphate synthetase 1
chr17_-_40169429 22.83 ENST00000316603.7
ENST00000588641.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chrX_+_70503037 22.74 ENST00000535149.1
non-POU domain containing, octamer-binding
chr16_-_28857677 22.68 ENST00000313511.3
Tu translation elongation factor, mitochondrial
chr1_+_228270361 22.64 ENST00000272102.5
ENST00000540651.1
ADP-ribosylation factor 1
chr11_-_14379997 22.54 ENST00000526063.1
ENST00000532814.1
related RAS viral (r-ras) oncogene homolog 2
chr3_+_197677047 22.46 ENST00000448864.1
ribosomal protein L35a
chr7_+_135242652 22.11 ENST00000285968.6
ENST00000440390.2
nucleoporin 205kDa
chr15_+_89010923 21.99 ENST00000353598.6
mitochondrial ribosomal protein S11
chr6_-_43027105 21.95 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr17_-_40169659 21.70 ENST00000457167.4
DnaJ (Hsp40) homolog, subfamily C, member 7
chr9_+_131452239 21.66 ENST00000372688.4
ENST00000372686.5
SET nuclear oncogene
chr20_+_30193083 21.58 ENST00000376112.3
ENST00000376105.3
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr3_+_184079492 21.29 ENST00000456318.1
ENST00000412877.1
ENST00000438240.1
polymerase (RNA) II (DNA directed) polypeptide H
chr20_-_49547910 21.22 ENST00000396032.3
activity-dependent neuroprotector homeobox
chr17_+_4699439 21.18 ENST00000270586.3
proteasome (prosome, macropain) subunit, beta type, 6
chr7_+_116502605 21.12 ENST00000458284.2
ENST00000490693.1
capping protein (actin filament) muscle Z-line, alpha 2
chr19_-_4670345 21.05 ENST00000599630.1
ENST00000262947.3
chromosome 19 open reading frame 10
chr1_+_228270784 21.05 ENST00000541182.1
ADP-ribosylation factor 1
chr1_+_155178518 21.04 ENST00000316721.4
metaxin 1
chr3_-_48647470 21.01 ENST00000203407.5
ubiquinol-cytochrome c reductase core protein I
chr4_-_103746683 20.89 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr7_+_2394445 20.81 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
eukaryotic translation initiation factor 3, subunit B
chr2_+_114647504 20.80 ENST00000263238.2
ARP3 actin-related protein 3 homolog (yeast)
chr4_-_103746924 20.55 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
ubiquitin-conjugating enzyme E2D 3
chr1_+_113161778 20.52 ENST00000263168.3
capping protein (actin filament) muscle Z-line, alpha 1
chr6_+_160211481 20.51 ENST00000367034.4
mitochondrial ribosomal protein L18
chr19_+_12848299 20.28 ENST00000357332.3
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chrX_+_48433326 20.23 ENST00000376755.1
RNA binding motif (RNP1, RRM) protein 3
chr12_-_49075941 20.18 ENST00000553086.1
ENST00000548304.1
KAT8 regulatory NSL complex subunit 2
chr11_+_4116054 20.17 ENST00000423050.2
ribonucleotide reductase M1
chr19_-_13068012 20.11 ENST00000316939.1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr9_+_140135665 19.95 ENST00000340384.4
tubulin, beta 4B class IVb
chr20_+_44441626 19.92 ENST00000372568.4
ubiquitin-conjugating enzyme E2C
chr11_+_4116005 19.83 ENST00000300738.5
ribonucleotide reductase M1
chr17_-_3571934 19.76 ENST00000225525.3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr12_+_93861264 19.71 ENST00000549982.1
ENST00000361630.2
mitochondrial ribosomal protein L42
chr14_+_23235886 19.71 ENST00000604262.1
ENST00000431881.2
ENST00000412791.1
ENST00000358043.5
oxidase (cytochrome c) assembly 1-like
chr2_+_242255275 19.63 ENST00000391971.2
septin 2
chr12_+_93861282 19.61 ENST00000552217.1
ENST00000393128.4
ENST00000547098.1
mitochondrial ribosomal protein L42
chr17_-_685559 19.57 ENST00000301329.6
glyoxalase domain containing 4
chr11_-_64013663 19.50 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_-_78120936 19.49 ENST00000576547.1
ENST00000269349.3
eukaryotic translation initiation factor 4A3
chr1_+_225965518 19.28 ENST00000304786.7
ENST00000366839.4
ENST00000366838.1
signal recognition particle 9kDa
chr17_-_40169161 19.23 ENST00000589586.2
ENST00000426588.3
ENST00000589576.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr18_-_812517 19.10 ENST00000584307.1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr3_-_52567792 18.98 ENST00000307092.4
ENST00000422318.2
ENST00000459839.1
5'-nucleotidase domain containing 2
chrX_+_47053208 18.97 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
ubiquitin-like modifier activating enzyme 1
chr11_-_111957451 18.88 ENST00000504148.2
ENST00000541231.1
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr17_-_685493 18.85 ENST00000536578.1
ENST00000301328.5
ENST00000576419.1
glyoxalase domain containing 4
chr19_+_36631867 18.77 ENST00000588780.1
calpain, small subunit 1
chr17_+_1733276 18.77 ENST00000254719.5
replication protein A1, 70kDa
chr6_-_31509714 18.66 ENST00000456662.1
ENST00000431908.1
ENST00000456976.1
ENST00000428450.1
ENST00000453105.2
ENST00000418897.1
ENST00000415382.2
ENST00000449074.2
ENST00000419020.1
ENST00000428098.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr6_-_42185583 18.62 ENST00000053468.3
mitochondrial ribosomal protein S10
chr4_+_83956312 18.53 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COP9 signalosome subunit 4
chr14_-_45603657 18.49 ENST00000396062.3
FK506 binding protein 3, 25kDa
chr5_+_170814803 18.42 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr3_+_23959185 18.40 ENST00000354811.5
ribosomal protein L15
chr4_+_83956237 18.39 ENST00000264389.2
COP9 signalosome subunit 4
chr3_-_49142178 18.32 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
glutaminyl-tRNA synthetase
chr17_+_66509019 18.27 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr22_-_36236265 18.21 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr21_-_27107344 18.15 ENST00000457143.2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr19_-_55791058 18.14 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr7_+_99686577 18.09 ENST00000303904.3
ENST00000419210.1
ENST00000418625.1
COP9 signalosome subunit 6
chr19_-_44031341 18.07 ENST00000600651.1
ethylmalonic encephalopathy 1
chr5_+_134094461 18.05 ENST00000452510.2
ENST00000354283.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr9_+_91926103 18.01 ENST00000314355.6
CDC28 protein kinase regulatory subunit 2
chr20_-_524415 17.94 ENST00000400217.2
casein kinase 2, alpha 1 polypeptide
chr17_-_79481666 17.92 ENST00000575659.1
actin, gamma 1
chr17_-_61905005 17.67 ENST00000584574.1
ENST00000585145.1
ENST00000427159.2
FtsJ homolog 3 (E. coli)
chr16_+_67261008 17.60 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
transmembrane protein 208
chr7_-_42971759 17.57 ENST00000538645.1
ENST00000445517.1
ENST00000223321.4
proteasome (prosome, macropain) subunit, alpha type, 2
chr3_+_172468505 17.52 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
epithelial cell transforming sequence 2 oncogene
chr21_-_27107198 17.48 ENST00000400094.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chrX_+_67718863 17.43 ENST00000374622.2
Yip1 domain family, member 6
chr11_-_34937858 17.43 ENST00000278359.5
APAF1 interacting protein
chr17_-_5322786 17.38 ENST00000225696.4
nucleoporin 88kDa
chr15_+_63340647 17.30 ENST00000404484.4
tropomyosin 1 (alpha)
chr19_-_39322299 17.29 ENST00000601094.1
ENST00000595567.1
ENST00000602115.1
ENST00000601778.1
ENST00000597205.1
ENST00000595470.1
enoyl CoA hydratase 1, peroxisomal
chr8_+_145149930 17.26 ENST00000318911.4
cytochrome c-1
chrX_-_48980098 17.23 ENST00000156109.5
G patch domain and KOW motifs
chr20_-_49575058 17.18 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chrX_-_114953669 17.16 ENST00000449327.1
Uncharacterized protein
chr19_+_39214797 17.12 ENST00000440400.1
actinin, alpha 4
chr22_+_21921994 17.10 ENST00000545681.1
ubiquitin-conjugating enzyme E2L 3
chr19_-_8386238 17.07 ENST00000301457.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr7_+_116502527 17.07 ENST00000361183.3
capping protein (actin filament) muscle Z-line, alpha 2
chr11_+_34938119 17.06 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
pyruvate dehydrogenase complex, component X
chrX_+_49028265 17.06 ENST00000376322.3
ENST00000376327.5
proteolipid protein 2 (colonic epithelium-enriched)
chr21_-_27107283 16.93 ENST00000284971.3
ENST00000400099.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_-_89357179 16.88 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chr3_+_23958632 16.88 ENST00000412097.1
ENST00000415719.1
ENST00000435882.1
ribosomal protein L15
chr20_+_44441304 16.87 ENST00000352551.5
ubiquitin-conjugating enzyme E2C
chr10_+_75910960 16.70 ENST00000539909.1
ENST00000286621.2
adenosine kinase
chr3_+_172468472 16.63 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr6_-_170862322 16.62 ENST00000262193.6
proteasome (prosome, macropain) subunit, beta type, 1
chr6_+_36562132 16.55 ENST00000373715.6
ENST00000339436.7
serine/arginine-rich splicing factor 3
chr17_-_4843206 16.54 ENST00000576951.1
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chrX_-_153285251 16.42 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr16_-_18801582 16.35 ENST00000565420.1
ribosomal protein S15a
chr1_+_155179012 16.31 ENST00000609421.1
metaxin 1
chr5_+_137514687 16.29 ENST00000394894.3
kinesin family member 20A
chr20_+_44441215 16.15 ENST00000356455.4
ENST00000405520.1
ubiquitin-conjugating enzyme E2C
chr19_-_44031375 16.07 ENST00000292147.2
ethylmalonic encephalopathy 1
chr12_-_117628333 16.06 ENST00000427718.2
F-box protein 21
chr3_-_58419537 16.06 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
pyruvate dehydrogenase (lipoamide) beta
chr19_+_55897699 16.04 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
ribosomal protein L28
chr3_-_67705006 16.02 ENST00000492795.1
ENST00000493112.1
ENST00000307227.5
succinate-CoA ligase, GDP-forming, beta subunit
chrX_+_153060090 16.01 ENST00000370086.3
ENST00000370085.3
signal sequence receptor, delta
chr10_+_75936444 15.99 ENST00000372734.3
ENST00000541550.1
adenosine kinase
chr11_-_34938039 15.97 ENST00000395787.3
APAF1 interacting protein
chr17_+_73257945 15.89 ENST00000579002.1
mitochondrial ribosomal protein S7
chr17_+_61904766 15.85 ENST00000581842.1
ENST00000582130.1
ENST00000584320.1
ENST00000585123.1
ENST00000580864.1
proteasome (prosome, macropain) 26S subunit, ATPase, 5
chr16_-_18801643 15.84 ENST00000322989.4
ENST00000563390.1
ribosomal protein S15a
chr15_+_63340858 15.70 ENST00000560615.1
tropomyosin 1 (alpha)
chr20_-_524455 15.69 ENST00000349736.5
ENST00000217244.3
casein kinase 2, alpha 1 polypeptide
chr17_+_7487146 15.67 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr2_+_242255297 15.58 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
septin 2
chr12_+_120875910 15.53 ENST00000551806.1
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr16_+_57481382 15.51 ENST00000564655.1
ENST00000567072.1
ENST00000567933.1
ENST00000563166.1
coenzyme Q9
chr1_+_42921761 15.50 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chr5_-_180669197 15.49 ENST00000502905.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr11_+_16760161 15.44 ENST00000524439.1
ENST00000422258.2
ENST00000528634.1
ENST00000525684.1
chromosome 11 open reading frame 58
chr17_+_30677136 15.43 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
zinc finger protein 207
chr17_+_7476136 15.40 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr20_+_52824367 15.36 ENST00000371419.2
prefoldin subunit 4
chrX_-_153285395 15.31 ENST00000369980.3
interleukin-1 receptor-associated kinase 1
chrX_+_118370288 15.28 ENST00000535419.1
progesterone receptor membrane component 1
chr19_+_19626531 15.25 ENST00000507754.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr5_-_140070897 15.22 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
histidyl-tRNA synthetase

Network of associatons between targets according to the STRING database.

First level regulatory network of YY1_YY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
24.2 72.7 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
16.0 64.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
14.6 43.7 GO:1902822 lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
13.7 13.7 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
12.9 38.8 GO:0045900 negative regulation of translational elongation(GO:0045900)
12.9 38.7 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
12.4 49.5 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
11.2 55.8 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
10.9 32.7 GO:0044209 AMP salvage(GO:0044209)
10.8 32.4 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
10.7 32.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
10.6 84.8 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
10.3 20.5 GO:0035928 rRNA import into mitochondrion(GO:0035928)
9.6 48.0 GO:0019348 dolichol metabolic process(GO:0019348)
9.5 75.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
9.4 28.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
9.3 111.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
8.9 26.7 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
8.9 70.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
8.8 26.5 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
8.5 25.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
8.5 34.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
8.3 24.9 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
8.2 32.7 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
8.1 32.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
8.0 16.0 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
7.7 23.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
7.7 30.6 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
7.5 52.3 GO:0033484 nitric oxide homeostasis(GO:0033484)
7.3 29.1 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
7.2 21.6 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
7.1 21.4 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
7.1 21.3 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
6.9 20.8 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
6.7 33.6 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
6.6 26.3 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
6.4 19.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
6.3 87.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
6.1 30.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
6.0 17.9 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
5.9 17.6 GO:0006624 vacuolar protein processing(GO:0006624)
5.8 40.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
5.8 5.8 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
5.7 17.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
5.7 34.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
5.7 403.6 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
5.6 39.5 GO:0043144 snoRNA processing(GO:0043144)
5.6 16.7 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
5.5 55.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
5.4 37.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
5.3 84.1 GO:0043248 proteasome assembly(GO:0043248)
5.2 10.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
5.2 57.2 GO:0006621 protein retention in ER lumen(GO:0006621)
5.2 25.9 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
5.1 30.6 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
5.1 25.5 GO:0071035 nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
4.9 44.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
4.8 19.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
4.8 33.4 GO:0070269 pyroptosis(GO:0070269)
4.8 310.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
4.7 52.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
4.7 9.5 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
4.5 13.5 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
4.5 139.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
4.3 12.8 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
4.3 59.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
4.2 16.9 GO:1904798 positive regulation of core promoter binding(GO:1904798)
4.2 67.5 GO:0000338 protein deneddylation(GO:0000338)
4.2 20.8 GO:0075525 viral translational termination-reinitiation(GO:0075525)
4.1 16.6 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
4.0 12.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
3.9 7.9 GO:1901983 regulation of protein acetylation(GO:1901983)
3.9 357.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
3.9 27.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
3.8 18.9 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
3.8 11.3 GO:0060920 atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
3.7 14.7 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
3.5 14.2 GO:0045218 zonula adherens maintenance(GO:0045218)
3.5 10.6 GO:0002276 basophil activation involved in immune response(GO:0002276)
3.5 14.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
3.5 14.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
3.4 13.8 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
3.4 3.4 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
3.4 17.0 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
3.4 20.4 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
3.4 37.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
3.3 9.9 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
3.3 9.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
3.3 23.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
3.3 19.8 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
3.3 19.7 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
3.2 45.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
3.2 53.8 GO:2000774 positive regulation of cellular senescence(GO:2000774)
3.1 12.5 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
3.1 21.9 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
3.0 15.1 GO:0006311 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
3.0 3.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
3.0 23.8 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
2.9 8.8 GO:0006167 AMP biosynthetic process(GO:0006167)
2.9 8.8 GO:0003164 His-Purkinje system development(GO:0003164)
2.9 14.5 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
2.9 11.6 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
2.8 47.9 GO:0002192 IRES-dependent translational initiation(GO:0002192)
2.8 24.8 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
2.7 35.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
2.7 77.3 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
2.6 13.2 GO:0035617 stress granule disassembly(GO:0035617)
2.6 28.9 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
2.6 18.4 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
2.6 7.9 GO:0090149 mitochondrial membrane fission(GO:0090149)
2.6 20.7 GO:0070475 rRNA base methylation(GO:0070475)
2.6 7.7 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
2.5 101.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
2.5 72.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
2.5 24.8 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
2.4 9.7 GO:0043555 regulation of translation in response to stress(GO:0043555)
2.4 7.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
2.4 16.9 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
2.4 19.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
2.4 9.5 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
2.4 16.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
2.4 4.7 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
2.4 4.7 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
2.4 49.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
2.3 9.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
2.3 7.0 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
2.3 11.6 GO:0090343 positive regulation of cell aging(GO:0090343)
2.3 77.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
2.2 13.1 GO:0071763 nuclear membrane organization(GO:0071763)
2.1 8.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
2.1 4.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.1 21.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
2.1 2.1 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
2.1 10.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
2.1 24.7 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
2.1 304.6 GO:0045047 protein targeting to ER(GO:0045047)
2.1 10.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
2.0 6.1 GO:0016259 selenocysteine metabolic process(GO:0016259) selenocysteine biosynthetic process(GO:0016260)
2.0 6.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
2.0 26.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.9 34.9 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
1.9 1.9 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.9 89.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
1.9 1.9 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
1.8 8.9 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
1.8 10.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.7 15.7 GO:0030091 protein repair(GO:0030091)
1.7 28.0 GO:0072321 chaperone-mediated protein transport(GO:0072321)
1.7 7.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
1.7 32.6 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
1.7 5.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
1.7 44.1 GO:0042255 ribosome assembly(GO:0042255)
1.7 60.9 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
1.7 3.4 GO:0034971 histone H3-R17 methylation(GO:0034971)
1.7 13.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
1.7 13.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
1.7 18.3 GO:0008216 spermidine metabolic process(GO:0008216)
1.6 6.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.6 3.3 GO:0035989 tendon development(GO:0035989)
1.6 8.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
1.6 1.6 GO:0043335 protein unfolding(GO:0043335)
1.6 16.3 GO:0010265 SCF complex assembly(GO:0010265)
1.6 17.9 GO:0045116 protein neddylation(GO:0045116)
1.6 6.5 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
1.6 8.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
1.6 4.8 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
1.6 17.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
1.6 22.1 GO:0006378 mRNA polyadenylation(GO:0006378)
1.6 7.9 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
1.6 4.7 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.6 9.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.6 4.7 GO:0006447 regulation of translational initiation by iron(GO:0006447)
1.6 14.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
1.6 11.0 GO:0003150 muscular septum morphogenesis(GO:0003150)
1.6 15.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
1.5 15.4 GO:1904424 regulation of GTP binding(GO:1904424)
1.5 3.1 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
1.5 1.5 GO:0035973 aggrephagy(GO:0035973)
1.5 18.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
1.5 6.0 GO:0090646 mitochondrial tRNA processing(GO:0090646)
1.5 31.5 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
1.5 4.5 GO:0034453 microtubule anchoring(GO:0034453)
1.5 35.6 GO:0006337 nucleosome disassembly(GO:0006337)
1.5 7.3 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
1.5 16.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
1.4 10.1 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
1.4 11.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
1.4 4.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
1.4 8.6 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
1.4 11.5 GO:0033523 histone H2B ubiquitination(GO:0033523)
1.4 2.8 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.4 4.1 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
1.3 9.4 GO:0070141 response to UV-A(GO:0070141)
1.3 14.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.3 9.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.3 4.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
1.3 24.8 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
1.3 13.0 GO:0031468 nuclear envelope reassembly(GO:0031468)
1.3 11.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.3 22.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
1.3 46.5 GO:0045841 negative regulation of mitotic metaphase/anaphase transition(GO:0045841) mitotic spindle checkpoint(GO:0071174) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100)
1.3 2.5 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.3 5.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
1.2 17.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
1.2 7.3 GO:0039526 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
1.2 15.7 GO:0019388 galactose catabolic process(GO:0019388)
1.2 9.6 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
1.2 12.0 GO:0045008 depyrimidination(GO:0045008)
1.2 4.8 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
1.2 55.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
1.2 19.8 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
1.2 4.6 GO:0008333 endosome to lysosome transport(GO:0008333)
1.2 13.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.1 9.1 GO:0001675 acrosome assembly(GO:0001675)
1.1 1.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
1.1 14.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.1 195.2 GO:0000910 cytokinesis(GO:0000910)
1.1 4.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
1.1 10.1 GO:0001878 response to yeast(GO:0001878)
1.1 101.1 GO:0048208 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
1.1 3.3 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
1.1 3.3 GO:0080009 mRNA methylation(GO:0080009)
1.1 11.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
1.1 19.2 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.1 3.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.1 9.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.0 10.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
1.0 4.2 GO:0042182 ketone catabolic process(GO:0042182)
1.0 4.0 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
1.0 5.0 GO:0051182 coenzyme transport(GO:0051182)
1.0 71.6 GO:0045454 cell redox homeostasis(GO:0045454)
1.0 10.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
1.0 12.8 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
1.0 3.9 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
1.0 29.1 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.0 1.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.0 32.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
1.0 2.9 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.9 17.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.9 3.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.9 3.7 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.9 3.6 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.9 22.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.9 38.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.9 23.4 GO:0006491 N-glycan processing(GO:0006491)
0.9 3.5 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.9 0.9 GO:0060462 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.9 25.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.9 2.6 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.8 2.5 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.8 24.3 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.8 4.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.8 17.6 GO:0046697 decidualization(GO:0046697)
0.8 2.4 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.8 9.6 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.8 3.2 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.8 11.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.8 3.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.8 23.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.8 2.4 GO:1902499 regulation of protein autoubiquitination(GO:1902498) positive regulation of protein autoubiquitination(GO:1902499)
0.8 2.3 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.8 10.1 GO:0010288 response to lead ion(GO:0010288)
0.8 4.7 GO:1903232 melanosome assembly(GO:1903232)
0.8 6.2 GO:0009650 UV protection(GO:0009650)
0.8 6.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.8 4.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.8 8.4 GO:0006694 steroid biosynthetic process(GO:0006694)
0.8 2.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.8 3.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.7 6.7 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476)
0.7 11.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.7 5.2 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.7 5.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.7 3.7 GO:0003322 pancreatic A cell development(GO:0003322)
0.7 3.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.7 4.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.7 0.7 GO:1902445 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.7 10.8 GO:0006449 regulation of translational termination(GO:0006449)
0.7 5.0 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.7 4.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.7 4.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.7 2.1 GO:0072599 establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.7 11.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.7 5.5 GO:0060056 mammary gland involution(GO:0060056)
0.7 6.8 GO:0009414 response to water deprivation(GO:0009414)
0.7 3.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.7 2.7 GO:0060434 bronchus morphogenesis(GO:0060434)
0.7 2.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.7 2.0 GO:0002752 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.7 70.6 GO:0006413 translational initiation(GO:0006413)
0.7 5.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.6 7.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.6 10.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.6 4.5 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.6 6.4 GO:0002934 desmosome organization(GO:0002934)
0.6 3.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.6 2.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.6 7.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.6 13.5 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.6 8.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.6 4.2 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.6 8.9 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.6 7.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.6 10.5 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.6 7.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.6 3.5 GO:0006789 bilirubin conjugation(GO:0006789)
0.6 10.8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.6 2.3 GO:2000618 regulation of histone H4-K16 acetylation(GO:2000618)
0.6 4.5 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.6 6.7 GO:0006108 malate metabolic process(GO:0006108)
0.6 1.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.6 4.4 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.5 3.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.5 1.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.5 20.7 GO:0006414 translational elongation(GO:0006414)
0.5 1.6 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 8.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.5 12.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 2.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.5 2.4 GO:0018345 protein palmitoylation(GO:0018345)
0.5 5.2 GO:0042026 protein refolding(GO:0042026)
0.5 3.3 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.5 4.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.5 2.3 GO:0016240 autophagosome docking(GO:0016240)
0.4 8.0 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.4 5.8 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.4 11.4 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.4 8.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.4 4.7 GO:0033197 response to vitamin E(GO:0033197)
0.4 1.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.4 2.2 GO:0007097 nuclear migration(GO:0007097)
0.4 7.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.4 8.6 GO:0033622 integrin activation(GO:0033622)
0.4 1.7 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716) melanocyte proliferation(GO:0097325)
0.4 3.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.4 2.1 GO:0034201 response to oleic acid(GO:0034201)
0.4 2.1 GO:0072205 metanephric collecting duct development(GO:0072205)
0.4 9.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.4 1.2 GO:0043297 apical junction assembly(GO:0043297)
0.4 5.7 GO:0001765 membrane raft assembly(GO:0001765)
0.4 22.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.4 3.5 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.4 30.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.4 2.7 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.4 1.5 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve development(GO:0021557) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.4 18.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.4 5.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.4 5.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.4 6.5 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.4 3.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.4 2.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.4 8.2 GO:0035987 endodermal cell differentiation(GO:0035987)
0.4 8.4 GO:0006903 vesicle targeting(GO:0006903)
0.4 5.8 GO:0032060 bleb assembly(GO:0032060)
0.4 3.3 GO:0071694 sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.4 27.1 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.4 5.7 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.4 1.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.3 2.8 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.3 4.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 5.8 GO:0000154 rRNA modification(GO:0000154)
0.3 19.7 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.3 13.7 GO:0045214 sarcomere organization(GO:0045214)
0.3 4.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.3 4.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.3 2.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.3 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 5.6 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.3 1.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.3 3.4 GO:0015886 heme transport(GO:0015886)
0.3 13.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.3 3.6 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.3 3.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.3 5.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.3 1.5 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.3 21.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.3 80.0 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.3 29.7 GO:0070268 cornification(GO:0070268)
0.3 13.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.3 1.8 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.3 1.5 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.3 4.6 GO:0006750 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.3 1.9 GO:0072718 response to cisplatin(GO:0072718)
0.3 7.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 0.8 GO:0042023 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.3 47.0 GO:0001649 osteoblast differentiation(GO:0001649)
0.3 1.0 GO:0051552 flavone metabolic process(GO:0051552)
0.3 1.5 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.3 5.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2 0.7 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.5 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 33.3 GO:0006457 protein folding(GO:0006457)
0.2 0.7 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.2 0.7 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.2 37.6 GO:0008360 regulation of cell shape(GO:0008360)
0.2 2.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 0.7 GO:0070831 basement membrane assembly(GO:0070831)
0.2 3.4 GO:0060065 uterus development(GO:0060065)
0.2 0.4 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.2 2.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 0.2 GO:0040031 snRNA modification(GO:0040031)
0.2 7.4 GO:0045727 positive regulation of translation(GO:0045727)
0.2 7.2 GO:0032272 negative regulation of protein polymerization(GO:0032272)
0.2 1.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 1.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 4.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 3.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.2 5.3 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 2.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.2 0.5 GO:0015680 intracellular copper ion transport(GO:0015680)
0.2 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 3.7 GO:0007565 female pregnancy(GO:0007565)
0.2 4.7 GO:0006270 DNA replication initiation(GO:0006270)
0.2 1.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 1.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 3.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 2.2 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.2 4.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 6.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 5.2 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 4.7 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.1 1.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.7 GO:1903313 positive regulation of mRNA metabolic process(GO:1903313)
0.1 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 4.0 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 3.6 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 2.7 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.1 1.5 GO:0034605 cellular response to heat(GO:0034605)
0.1 5.9 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.1 4.2 GO:0006826 iron ion transport(GO:0006826)
0.1 0.3 GO:0030307 positive regulation of cell growth(GO:0030307)
0.1 1.7 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 1.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.7 GO:0042407 cristae formation(GO:0042407)
0.1 6.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.6 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.1 0.3 GO:0051685 endoplasmic reticulum localization(GO:0051643) maintenance of ER location(GO:0051685)
0.1 4.2 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.1 3.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 0.8 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1 4.2 GO:0031016 pancreas development(GO:0031016)
0.1 3.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 4.0 GO:0005977 glycogen metabolic process(GO:0005977)
0.1 1.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 7.8 GO:0002576 platelet degranulation(GO:0002576)
0.1 5.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.6 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 1.6 GO:0090398 cellular senescence(GO:0090398)
0.1 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:0006366 transcription from RNA polymerase II promoter(GO:0006366)
0.1 1.1 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.1 0.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.1 2.1 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 2.0 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 0.3 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 2.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.0 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.4 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019) negative regulation of gap junction assembly(GO:1903597)
0.0 1.4 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.5 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 1.2 GO:0006397 mRNA processing(GO:0006397)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.7 GO:0048514 blood vessel morphogenesis(GO:0048514)
0.0 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.8 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.3 GO:2000272 negative regulation of receptor activity(GO:2000272)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
13.2 211.6 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
11.8 82.6 GO:0016272 prefoldin complex(GO:0016272)
11.7 82.0 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
11.4 34.1 GO:0071159 NF-kappaB complex(GO:0071159)
10.8 32.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
10.0 40.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
9.7 77.9 GO:0042382 paraspeckles(GO:0042382)
9.7 29.1 GO:0005588 collagen type V trimer(GO:0005588)
9.3 27.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
8.5 93.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
8.2 33.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
8.1 32.4 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
8.0 79.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
7.9 70.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
7.6 206.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
7.1 70.9 GO:0000796 condensin complex(GO:0000796)
6.8 34.2 GO:0097149 centralspindlin complex(GO:0097149)
6.8 20.4 GO:0035370 UBC13-UEV1A complex(GO:0035370)
6.7 33.7 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
6.5 51.8 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
6.3 31.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
6.3 25.2 GO:0070985 TFIIK complex(GO:0070985)
6.2 112.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
6.2 104.9 GO:0034709 methylosome(GO:0034709)
6.1 36.5 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
6.0 17.9 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
5.9 111.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
5.8 23.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
5.5 21.9 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
5.5 27.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
5.3 58.0 GO:0031595 nuclear proteasome complex(GO:0031595)
5.2 78.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
5.1 40.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
5.0 15.1 GO:0032302 MutSbeta complex(GO:0032302)
5.0 14.9 GO:1903349 omegasome membrane(GO:1903349)
4.8 100.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
4.7 23.7 GO:0034457 Mpp10 complex(GO:0034457)
4.7 14.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
4.6 69.1 GO:0008290 F-actin capping protein complex(GO:0008290)
4.6 193.3 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
4.5 58.3 GO:0042555 MCM complex(GO:0042555)
4.4 13.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
4.4 48.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
4.4 30.7 GO:0016589 NURF complex(GO:0016589)
4.3 30.0 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
3.9 51.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
3.9 35.3 GO:0005638 lamin filament(GO:0005638)
3.9 231.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
3.6 10.9 GO:0034455 t-UTP complex(GO:0034455)
3.5 13.8 GO:1990423 RZZ complex(GO:1990423)
3.4 3.4 GO:0071203 WASH complex(GO:0071203)
3.3 13.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
3.3 33.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
3.3 23.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
3.3 13.2 GO:0044611 nuclear pore inner ring(GO:0044611)
3.3 26.3 GO:0070552 BRISC complex(GO:0070552)
3.2 22.6 GO:0046581 intercellular canaliculus(GO:0046581)
3.2 22.2 GO:0005787 signal peptidase complex(GO:0005787)
3.2 9.5 GO:0034686 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
3.2 94.9 GO:0005680 anaphase-promoting complex(GO:0005680)
3.1 40.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
3.1 24.8 GO:0005687 U4 snRNP(GO:0005687)
3.1 9.2 GO:0005826 actomyosin contractile ring(GO:0005826) GID complex(GO:0034657)
3.0 15.2 GO:0005721 pericentric heterochromatin(GO:0005721)
3.0 8.9 GO:0005873 plus-end kinesin complex(GO:0005873)
3.0 8.9 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
3.0 20.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.9 20.1 GO:0061700 GATOR2 complex(GO:0061700)
2.8 45.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
2.8 74.7 GO:0032040 small-subunit processome(GO:0032040)
2.7 13.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
2.7 13.4 GO:0035061 interchromatin granule(GO:0035061)
2.6 7.9 GO:0031262 Ndc80 complex(GO:0031262)
2.6 31.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
2.4 24.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
2.4 19.2 GO:0005610 laminin-5 complex(GO:0005610)
2.4 56.9 GO:0030137 COPI-coated vesicle(GO:0030137)
2.4 26.0 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
2.4 18.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
2.3 9.2 GO:0071001 U4/U6 snRNP(GO:0071001)
2.3 6.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
2.3 57.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
2.2 17.9 GO:0032133 chromosome passenger complex(GO:0032133)
2.2 15.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.1 10.6 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
2.0 24.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
2.0 28.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
2.0 43.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
2.0 21.6 GO:0005838 proteasome regulatory particle(GO:0005838)
1.9 19.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.9 11.6 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
1.9 42.1 GO:0031105 septin complex(GO:0031105)
1.9 15.3 GO:0034719 SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
1.9 204.5 GO:0015934 large ribosomal subunit(GO:0015934)
1.9 100.8 GO:0005871 kinesin complex(GO:0005871)
1.8 34.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
1.8 18.1 GO:0031616 spindle pole centrosome(GO:0031616)
1.8 23.5 GO:0008385 IkappaB kinase complex(GO:0008385)
1.8 19.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.8 19.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.8 33.8 GO:0036020 endolysosome membrane(GO:0036020)
1.7 77.6 GO:0008180 COP9 signalosome(GO:0008180)
1.7 26.8 GO:0000178 exosome (RNase complex)(GO:0000178)
1.7 51.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.6 19.7 GO:0005746 mitochondrial respiratory chain(GO:0005746)
1.6 4.8 GO:0031415 NatA complex(GO:0031415)
1.6 12.8 GO:0097208 alveolar lamellar body(GO:0097208)
1.6 19.2 GO:0042405 nuclear inclusion body(GO:0042405)
1.6 21.8 GO:0005662 DNA replication factor A complex(GO:0005662)
1.5 7.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
1.5 20.1 GO:0097433 dense body(GO:0097433)
1.5 6.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.5 12.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.5 4.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
1.5 6.0 GO:0032044 DSIF complex(GO:0032044)
1.5 158.8 GO:0005840 ribosome(GO:0005840)
1.5 11.7 GO:0051286 cell tip(GO:0051286)
1.4 8.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
1.4 8.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
1.4 4.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
1.4 26.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.4 9.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
1.3 88.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.3 10.7 GO:0042824 MHC class I peptide loading complex(GO:0042824)
1.3 16.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
1.3 30.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.2 6.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
1.2 12.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.2 67.5 GO:0005801 cis-Golgi network(GO:0005801)
1.2 12.0 GO:0090543 Flemming body(GO:0090543)
1.2 13.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.2 33.3 GO:0031143 pseudopodium(GO:0031143)
1.1 8.0 GO:1990635 proximal dendrite(GO:1990635)
1.1 22.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.1 19.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
1.1 14.6 GO:0005869 dynactin complex(GO:0005869)
1.1 3.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
1.1 7.7 GO:0005685 U1 snRNP(GO:0005685)
1.1 10.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.0 4.9 GO:0071986 Ragulator complex(GO:0071986)
0.9 3.8 GO:0089701 U2AF(GO:0089701)
0.9 4.7 GO:0033503 HULC complex(GO:0033503)
0.9 5.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.9 24.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.9 4.7 GO:0031905 early endosome lumen(GO:0031905)
0.9 7.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.9 78.6 GO:0043195 terminal bouton(GO:0043195)
0.8 10.7 GO:0030904 retromer complex(GO:0030904)
0.8 7.3 GO:0032059 bleb(GO:0032059)
0.8 6.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.8 8.5 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.8 26.5 GO:0000502 proteasome complex(GO:0000502)
0.8 18.1 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.7 45.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.7 6.6 GO:0061574 ASAP complex(GO:0061574)
0.7 10.2 GO:0010369 chromocenter(GO:0010369)
0.7 32.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.7 49.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.6 1.9 GO:0001740 Barr body(GO:0001740)
0.6 1.9 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.6 2.6 GO:0000798 nuclear cohesin complex(GO:0000798)
0.6 5.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.6 4.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6 3.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 3.7 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.6 18.5 GO:0030057 desmosome(GO:0030057)
0.6 3.1 GO:0001739 sex chromatin(GO:0001739)
0.6 14.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.6 4.2 GO:0005955 calcineurin complex(GO:0005955)
0.6 149.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.6 1.1 GO:0001940 male pronucleus(GO:0001940)
0.6 7.3 GO:0005577 fibrinogen complex(GO:0005577)
0.6 2.2 GO:0030686 90S preribosome(GO:0030686)
0.5 8.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.5 13.1 GO:0042629 mast cell granule(GO:0042629)
0.5 7.0 GO:0017119 Golgi transport complex(GO:0017119)
0.5 1.6 GO:0032039 integrator complex(GO:0032039)
0.5 3.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.5 7.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.5 72.9 GO:0030496 midbody(GO:0030496)
0.5 3.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.5 1.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 26.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.5 12.0 GO:0002080 acrosomal membrane(GO:0002080)
0.5 57.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.5 8.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.5 5.9 GO:0030478 actin cap(GO:0030478)
0.4 4.5 GO:0097546 ciliary base(GO:0097546)
0.4 25.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.4 2.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 2.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.4 4.4 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.4 37.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.4 6.1 GO:0032433 filopodium tip(GO:0032433)
0.4 9.2 GO:0000421 autophagosome membrane(GO:0000421)
0.4 17.8 GO:0043034 costamere(GO:0043034)
0.4 2.1 GO:0035859 Seh1-associated complex(GO:0035859) Iml1 complex(GO:1990130)
0.4 4.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 8.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.4 39.5 GO:0035579 specific granule membrane(GO:0035579)
0.4 14.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 6.6 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4 1.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.4 18.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.4 6.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.4 24.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 3.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 7.3 GO:1904115 axon cytoplasm(GO:1904115)
0.3 11.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 1.6 GO:0032021 NELF complex(GO:0032021)
0.3 8.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 5.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 16.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 10.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 3.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.3 3.3 GO:0009925 basal plasma membrane(GO:0009925)
0.3 2.9 GO:0005876 spindle microtubule(GO:0005876)
0.3 2.6 GO:0035861 site of double-strand break(GO:0035861)
0.3 1.3 GO:0070847 core mediator complex(GO:0070847)
0.2 0.5 GO:0070939 Dsl1p complex(GO:0070939)
0.2 1.2 GO:0005916 fascia adherens(GO:0005916)
0.2 11.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 12.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 8.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.2 0.9 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 3.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 2.3 GO:0097346 INO80-type complex(GO:0097346)
0.2 2.5 GO:0071141 SMAD protein complex(GO:0071141)
0.2 3.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 4.1 GO:0000812 Swr1 complex(GO:0000812)
0.2 1.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 2.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 7.6 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 14.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 3.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 0.7 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 7.9 GO:0005811 lipid particle(GO:0005811)
0.2 7.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 3.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 24.3 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 2.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 5.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 6.1 GO:0031526 brush border membrane(GO:0031526)
0.1 1.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 1.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.2 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.9 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 3.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 3.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 2.4 GO:0001533 cornified envelope(GO:0001533)
0.1 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 4.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 4.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 3.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 9.3 GO:0001650 fibrillar center(GO:0001650)
0.1 2.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 5.7 GO:0005604 basement membrane(GO:0005604)
0.1 5.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 4.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.2 GO:0043679 axon terminus(GO:0043679)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.8 GO:0000922 spindle pole(GO:0000922)
0.0 1.4 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0031201 SNARE complex(GO:0031201)
0.0 5.3 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
16.0 64.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
13.5 53.9 GO:0005046 KDEL sequence binding(GO:0005046)
10.7 32.0 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
10.7 32.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
10.5 73.4 GO:0050815 phosphoserine binding(GO:0050815)
10.2 71.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
10.0 40.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
9.3 27.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
8.9 26.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
8.7 26.0 GO:0005047 signal recognition particle binding(GO:0005047)
8.1 32.4 GO:0000104 succinate dehydrogenase activity(GO:0000104)
8.1 242.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
8.1 32.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
7.9 23.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
7.3 58.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
7.1 21.4 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
6.5 25.9 GO:0004774 succinate-CoA ligase activity(GO:0004774)
5.9 17.7 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
5.8 34.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
5.8 17.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
5.7 56.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
5.3 58.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
5.2 15.7 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
5.2 15.6 GO:0001069 regulatory region RNA binding(GO:0001069)
5.1 15.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
5.1 271.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
5.1 55.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
5.0 15.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
5.0 25.0 GO:0015140 malate transmembrane transporter activity(GO:0015140)
4.8 14.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
4.8 14.3 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
4.5 31.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
4.5 45.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
4.2 21.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
4.2 12.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
4.1 33.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
4.1 28.5 GO:0030621 U4 snRNA binding(GO:0030621)
3.9 27.3 GO:0033592 RNA strand annealing activity(GO:0033592)
3.7 18.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
3.6 165.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
3.6 17.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
3.6 14.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
3.5 10.5 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
3.5 10.4 GO:0004766 spermidine synthase activity(GO:0004766)
3.4 3.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
3.4 33.8 GO:0008097 5S rRNA binding(GO:0008097)
3.3 13.2 GO:0099609 microtubule lateral binding(GO:0099609)
3.3 88.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
3.3 26.3 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
3.2 25.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
3.2 19.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
3.0 62.7 GO:0001055 RNA polymerase II activity(GO:0001055)
2.8 8.5 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
2.8 8.5 GO:0035613 RNA stem-loop binding(GO:0035613)
2.7 184.0 GO:0003743 translation initiation factor activity(GO:0003743)
2.7 5.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
2.6 60.7 GO:0008327 methyl-CpG binding(GO:0008327)
2.6 7.9 GO:0000253 3-keto sterol reductase activity(GO:0000253)
2.6 15.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
2.6 7.8 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
2.6 5.2 GO:0043532 angiostatin binding(GO:0043532)
2.6 18.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.5 85.4 GO:0001671 ATPase activator activity(GO:0001671)
2.5 519.7 GO:0003735 structural constituent of ribosome(GO:0003735)
2.5 7.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
2.4 21.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
2.4 29.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
2.4 16.8 GO:0008312 7S RNA binding(GO:0008312)
2.4 7.2 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
2.4 4.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
2.3 43.7 GO:0016004 phospholipase activator activity(GO:0016004)
2.3 105.5 GO:0003785 actin monomer binding(GO:0003785)
2.3 27.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
2.2 8.9 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
2.2 11.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
2.2 35.4 GO:0019843 rRNA binding(GO:0019843)
2.1 15.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
2.1 8.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
2.1 44.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
2.1 2.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
2.1 10.5 GO:1990460 leptin receptor binding(GO:1990460)
2.1 12.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
2.1 8.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
2.0 6.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
2.0 8.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
2.0 20.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.0 12.0 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
2.0 9.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.9 11.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.9 32.7 GO:0019206 nucleoside kinase activity(GO:0019206)
1.9 9.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.9 9.4 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
1.9 7.4 GO:0043515 kinetochore binding(GO:0043515)
1.8 7.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
1.8 63.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.7 19.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.7 60.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
1.7 35.3 GO:0070628 proteasome binding(GO:0070628)
1.7 8.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
1.7 69.7 GO:0004532 exoribonuclease activity(GO:0004532)
1.7 5.0 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
1.6 11.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.6 4.8 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
1.6 6.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
1.6 4.7 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
1.6 9.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.6 31.5 GO:0005537 mannose binding(GO:0005537)
1.6 45.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.6 21.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
1.5 4.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.5 10.7 GO:0050733 RS domain binding(GO:0050733)
1.5 4.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
1.5 10.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.5 9.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.5 12.0 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
1.5 1.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.4 25.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.4 8.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.4 11.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.4 45.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.3 6.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.3 12.0 GO:0070883 pre-miRNA binding(GO:0070883)
1.3 21.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
1.3 11.9 GO:0015288 porin activity(GO:0015288)
1.3 34.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.3 9.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
1.3 9.1 GO:0048408 epidermal growth factor binding(GO:0048408)
1.3 3.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.3 10.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
1.2 54.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
1.2 6.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
1.2 118.1 GO:0008307 structural constituent of muscle(GO:0008307)
1.2 14.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.2 16.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.2 12.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.2 4.9 GO:0036033 mediator complex binding(GO:0036033)
1.2 12.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.2 9.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.2 55.1 GO:0051879 Hsp90 protein binding(GO:0051879)
1.2 1.2 GO:0071253 connexin binding(GO:0071253)
1.2 8.2 GO:0030911 TPR domain binding(GO:0030911)
1.2 45.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.2 4.7 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
1.2 2.3 GO:0001540 beta-amyloid binding(GO:0001540)
1.2 28.8 GO:0003746 translation elongation factor activity(GO:0003746)
1.1 22.8 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
1.1 3.4 GO:0033149 FFAT motif binding(GO:0033149)
1.1 6.7 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
1.1 6.7 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
1.1 8.8 GO:0016842 amidine-lyase activity(GO:0016842)
1.1 7.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.1 3.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
1.1 7.4 GO:0035174 histone serine kinase activity(GO:0035174)
1.0 67.1 GO:0005507 copper ion binding(GO:0005507)
1.0 42.6 GO:0004364 glutathione transferase activity(GO:0004364)
1.0 8.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
1.0 2.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
1.0 14.6 GO:0070717 poly-purine tract binding(GO:0070717)
1.0 2.9 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
1.0 5.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.0 2.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.9 3.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.9 9.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.9 15.7 GO:0003680 AT DNA binding(GO:0003680)
0.9 13.7 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.9 58.7 GO:0019003 GDP binding(GO:0019003)
0.9 19.2 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.9 21.8 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.9 4.4 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.8 29.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.8 22.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.8 39.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.8 17.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.8 2.5 GO:0035500 MH2 domain binding(GO:0035500)
0.8 19.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.8 8.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.8 2.4 GO:0070984 SET domain binding(GO:0070984)
0.8 14.4 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.8 13.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.8 9.4 GO:0043274 phospholipase binding(GO:0043274)
0.8 7.9 GO:0015266 protein channel activity(GO:0015266)
0.8 10.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.8 31.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.8 6.2 GO:0003696 satellite DNA binding(GO:0003696)
0.8 4.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.8 4.5 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.7 18.0 GO:0070064 proline-rich region binding(GO:0070064)
0.7 6.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.7 32.1 GO:0050699 WW domain binding(GO:0050699)
0.7 14.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.7 3.7 GO:0097016 L27 domain binding(GO:0097016)
0.7 0.7 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.7 12.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.7 7.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.7 7.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.7 4.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.7 2.1 GO:0000150 recombinase activity(GO:0000150)
0.7 4.9 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.7 7.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.7 17.0 GO:0043022 ribosome binding(GO:0043022)
0.7 6.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.7 7.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.7 10.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.7 3.3 GO:0050436 microfibril binding(GO:0050436)
0.6 6.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.6 4.5 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.6 9.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.6 3.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.6 20.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.6 2.4 GO:0008432 JUN kinase binding(GO:0008432)
0.6 10.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.6 2.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.6 12.3 GO:0050811 GABA receptor binding(GO:0050811)
0.6 4.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.6 5.8 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.6 2.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.6 16.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.6 3.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.5 51.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.5 22.9 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.5 12.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.5 4.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5 3.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.5 27.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.5 17.1 GO:0019956 chemokine binding(GO:0019956)
0.5 12.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.5 4.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5 1.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 5.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.5 5.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.5 5.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.5 6.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.5 4.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.5 11.3 GO:0042605 peptide antigen binding(GO:0042605)
0.4 4.5 GO:0051434 BH3 domain binding(GO:0051434)
0.4 6.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.4 18.8 GO:0042169 SH2 domain binding(GO:0042169)
0.4 6.9 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.4 3.4 GO:0030274 LIM domain binding(GO:0030274)
0.4 3.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.4 2.9 GO:0035198 miRNA binding(GO:0035198)
0.4 14.3 GO:0005080 protein kinase C binding(GO:0005080)
0.4 10.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 12.0 GO:0051018 protein kinase A binding(GO:0051018)
0.4 3.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 22.3 GO:0003678 DNA helicase activity(GO:0003678)
0.4 13.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 23.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.4 10.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.4 8.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.4 2.6 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 4.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.4 2.1 GO:0005499 vitamin D binding(GO:0005499)
0.3 3.4 GO:0015232 heme transporter activity(GO:0015232)
0.3 4.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 2.3 GO:0016421 CoA carboxylase activity(GO:0016421)
0.3 1.6 GO:0048156 tau protein binding(GO:0048156)
0.3 13.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 3.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.3 1.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.3 2.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.3 4.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 12.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.3 5.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 0.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3 11.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.3 1.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.3 3.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 2.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 1.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.3 8.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.3 17.0 GO:0051087 chaperone binding(GO:0051087)
0.3 41.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.3 1.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 3.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 0.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 11.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.2 6.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 11.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.2 77.7 GO:0005525 GTP binding(GO:0005525)
0.2 0.5 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 4.7 GO:0090484 drug transporter activity(GO:0090484)
0.2 0.7 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.2 39.3 GO:0008201 heparin binding(GO:0008201)
0.2 0.7 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.2 22.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 13.8 GO:0009055 electron carrier activity(GO:0009055)
0.2 2.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 2.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 2.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 4.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 22.6 GO:0005178 integrin binding(GO:0005178)
0.2 0.8 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 12.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.2 12.6 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.2 0.9 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 4.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 73.8 GO:0003779 actin binding(GO:0003779)
0.2 2.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 10.4 GO:0030165 PDZ domain binding(GO:0030165)
0.2 3.0 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 3.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 0.1 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.1 2.2 GO:0019894 kinesin binding(GO:0019894)
0.1 12.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.9 GO:0098821 BMP receptor activity(GO:0098821)
0.1 32.5 GO:0044389 ubiquitin-like protein ligase binding(GO:0044389)
0.1 3.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.2 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.8 GO:0004529 exodeoxyribonuclease activity(GO:0004529) exodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016895) 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 2.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.6 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 4.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.1 GO:0005112 Notch binding(GO:0005112)
0.1 1.2 GO:0019900 kinase binding(GO:0019900)
0.1 0.2 GO:0005113 patched binding(GO:0005113)
0.1 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 5.0 GO:0005496 steroid binding(GO:0005496)
0.1 0.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 13.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 5.3 GO:0005179 hormone activity(GO:0005179)
0.0 1.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.9 GO:0016209 antioxidant activity(GO:0016209)
0.0 5.1 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 81.1 PID ARF 3PATHWAY Arf1 pathway
3.0 211.2 PID IGF1 PATHWAY IGF1 pathway
2.6 158.7 PID AURORA B PATHWAY Aurora B signaling
2.6 146.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
2.0 82.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
1.8 30.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
1.8 25.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.7 48.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
1.6 55.3 PID IL1 PATHWAY IL1-mediated signaling events
1.4 43.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
1.4 44.1 PID IL3 PATHWAY IL3-mediated signaling events
1.4 6.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
1.3 65.1 PID PLK1 PATHWAY PLK1 signaling events
1.2 28.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.2 9.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.1 44.8 PID NCADHERIN PATHWAY N-cadherin signaling events
1.1 23.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
1.0 15.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.9 21.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.8 18.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.8 20.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.8 6.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.8 78.1 PID CMYB PATHWAY C-MYB transcription factor network
0.7 32.4 NABA COLLAGENS Genes encoding collagen proteins
0.7 78.0 PID E2F PATHWAY E2F transcription factor network
0.7 7.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.6 6.4 PID ATM PATHWAY ATM pathway
0.6 74.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.6 13.7 PID BARD1 PATHWAY BARD1 signaling events
0.6 12.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.5 19.6 PID ATR PATHWAY ATR signaling pathway
0.5 12.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.5 20.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.5 19.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.5 15.0 PID INSULIN PATHWAY Insulin Pathway
0.5 15.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.4 26.0 PID CDC42 PATHWAY CDC42 signaling events
0.4 6.2 PID ALK2 PATHWAY ALK2 signaling events
0.4 10.3 PID FOXO PATHWAY FoxO family signaling
0.3 12.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 15.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.3 16.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.3 11.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 15.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.3 2.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 4.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.3 10.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.3 5.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 5.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 2.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 4.0 ST GA13 PATHWAY G alpha 13 Pathway
0.2 4.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 5.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 5.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 6.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 13.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 2.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 4.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 11.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 0.7 PID MYC PATHWAY C-MYC pathway
0.1 1.9 PID ALK1 PATHWAY ALK1 signaling events
0.1 7.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 2.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 6.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 2.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 27.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 4.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 65.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
6.0 12.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
5.5 406.5 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
5.3 123.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
5.2 186.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
4.9 415.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
4.1 37.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
3.9 153.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
3.9 85.4 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
3.7 29.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
3.7 33.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
3.6 57.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
3.6 270.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
3.3 29.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
3.2 38.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
3.1 12.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
2.7 159.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
2.7 58.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
2.6 38.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
2.6 54.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
2.6 35.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
2.5 30.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
2.3 74.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
2.3 367.7 REACTOME TRANSLATION Genes involved in Translation
2.2 113.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
2.1 113.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
2.1 59.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
2.0 8.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
2.0 125.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
2.0 48.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.9 33.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.9 80.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
1.9 3.8 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
1.8 32.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
1.8 45.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
1.8 45.8 REACTOME KINESINS Genes involved in Kinesins
1.8 59.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.7 36.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
1.7 32.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
1.7 34.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.7 11.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.6 13.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.6 24.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.5 43.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
1.5 17.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
1.4 26.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
1.4 11.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
1.3 38.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
1.3 32.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.3 22.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.3 13.9 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
1.3 15.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.2 20.7 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
1.1 13.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.1 9.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.1 57.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.1 12.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
1.0 21.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.9 24.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.9 8.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.8 19.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.8 12.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.8 34.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.8 4.7 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.8 38.4 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.8 70.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.8 26.3 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.7 13.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.7 74.4 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.7 16.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.7 6.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.7 14.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.6 12.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.6 5.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.6 37.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.6 15.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.6 14.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.5 1.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.5 12.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.5 26.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.5 33.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.5 24.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.5 10.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.5 15.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.5 13.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.5 3.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.5 3.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.5 16.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.4 11.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.4 6.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.4 14.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.4 2.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.4 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.4 11.3 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.3 7.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 7.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.3 6.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 44.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.3 7.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 3.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 6.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.3 10.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 5.7 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.3 6.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 19.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 3.6 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 8.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 4.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 4.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 22.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.2 2.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 6.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 3.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 2.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 3.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.2 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.1 1.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.0 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 2.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones