Project
averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for ZBTB7A_ZBTB7C
Z-value: 1.34
Motif logo
Transcription factors associated with ZBTB7A_ZBTB7C
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZBTB7A | hg19_v2_chr19_-_4066890_4066943 | 0.38 | 4.1e-09 | Click! |
| ZBTB7C | hg19_v2_chr18_-_45663666_45663732, hg19_v2_chr18_-_45935663_45935793 | 0.03 | 6.8e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZBTB7A_ZBTB7C
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 45.1 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 33.3 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.1 | 22.5 | GO:0006469 | negative regulation of protein kinase activity(GO:0006469) |
| 0.1 | 21.2 | GO:0007568 | aging(GO:0007568) |
| 5.3 | 21.1 | GO:1903288 | protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288) |
| 1.2 | 18.0 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 6.0 | 17.9 | GO:0007412 | axon target recognition(GO:0007412) |
| 2.2 | 17.8 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 2.4 | 16.8 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 1.7 | 16.6 | GO:0009249 | protein lipoylation(GO:0009249) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 75.7 | GO:0005856 | cytoskeleton(GO:0005856) |
| 0.0 | 66.9 | GO:0016021 | integral component of membrane(GO:0016021) |
| 5.8 | 46.2 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.3 | 29.5 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 2.4 | 29.2 | GO:0033010 | paranodal junction(GO:0033010) |
| 1.1 | 21.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.4 | 17.9 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 1.8 | 17.8 | GO:0045180 | basal cortex(GO:0045180) |
| 1.1 | 16.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 12.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 105.9 | GO:0005525 | GTP binding(GO:0005525) |
| 0.9 | 45.1 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 1.3 | 21.1 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.7 | 18.0 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 4.5 | 17.9 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.7 | 17.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 5.4 | 16.2 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.1 | 15.4 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 14.0 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.4 | 13.7 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 17.9 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 15.5 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.3 | 14.6 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.2 | 12.4 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.2 | 10.1 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.5 | 9.5 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.2 | 7.2 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 5.1 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 3.7 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 3.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 23.7 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.5 | 16.1 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 1.5 | 14.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.2 | 10.4 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 10.0 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.3 | 9.5 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 8.9 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 8.4 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 8.4 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.1 | 7.9 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |