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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZNF148

Z-value: 1.16

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Transcription factors associated with ZNF148

Gene Symbol Gene ID Gene Info
ZNF148
ENSG00000163848.14 zinc finger protein 148

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF148hg19_v2_chr3_-_125094093_125094198-0.045.8e-01Click!

Activity profile of ZNF148 motif

Sorted Z-values of ZNF148 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_42992856 19.24 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
GFAP
glial fibrillary acidic protein
chr11_+_63448955 16.64 ENST00000377819.5
ENST00000339997.4
ENST00000540798.1
ENST00000545432.1
ENST00000543552.1
ENST00000537981.1
RTN3
reticulon 3
chr19_+_41725088 13.62 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr5_+_71403061 13.14 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr11_+_63448918 11.87 ENST00000341307.2
ENST00000356000.3
ENST00000542238.1
RTN3
reticulon 3
chr14_-_60337684 10.74 ENST00000267484.5
RTN1
reticulon 1
chr3_+_159557637 9.12 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr12_-_49582978 8.55 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr12_-_49582593 8.11 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr11_+_124609823 8.05 ENST00000412681.2
NRGN
neurogranin (protein kinase C substrate, RC3)
chr11_+_124609742 7.98 ENST00000284292.6
NRGN
neurogranin (protein kinase C substrate, RC3)
chr22_+_32340481 7.62 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr20_+_10199468 7.23 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr7_+_100770328 7.09 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr11_+_46402297 6.46 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr3_+_238273 6.46 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr1_-_156217822 6.40 ENST00000368270.1
PAQR6
progestin and adipoQ receptor family member VI
chr12_+_120933904 6.34 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
DYNLL1
dynein, light chain, LC8-type 1
chr1_-_156217875 6.30 ENST00000292291.5
PAQR6
progestin and adipoQ receptor family member VI
chr12_+_120933859 6.28 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
DYNLL1
dynein, light chain, LC8-type 1
chr14_+_96505659 6.15 ENST00000555004.1
C14orf132
chromosome 14 open reading frame 132
chrX_+_114795489 6.06 ENST00000355899.3
ENST00000537301.1
ENST00000289290.3
PLS3
plastin 3
chr11_-_61735103 5.97 ENST00000529191.1
ENST00000529631.1
ENST00000530019.1
ENST00000529548.1
ENST00000273550.7
FTH1
ferritin, heavy polypeptide 1
chr5_+_173472607 5.95 ENST00000303177.3
ENST00000519867.1
NSG2
Neuron-specific protein family member 2
chr1_-_156217829 5.91 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
PAQR6
progestin and adipoQ receptor family member VI
chr12_+_6309517 5.90 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr9_+_131314859 5.85 ENST00000358161.5
ENST00000372731.4
ENST00000372739.3
SPTAN1
spectrin, alpha, non-erythrocytic 1
chr1_-_11714700 5.84 ENST00000354287.4
FBXO2
F-box protein 2
chr19_+_41725140 5.79 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr3_-_49907323 5.55 ENST00000296471.7
ENST00000488336.1
ENST00000467248.1
ENST00000466940.1
ENST00000463537.1
ENST00000480398.2
CAMKV
CaM kinase-like vesicle-associated
chr6_-_46459675 5.42 ENST00000306764.7
RCAN2
regulator of calcineurin 2
chr16_+_6069586 5.39 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_+_86274145 5.37 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
GRM3
glutamate receptor, metabotropic 3
chr16_+_30078811 5.37 ENST00000564688.1
ALDOA
aldolase A, fructose-bisphosphate
chr10_+_70748487 5.24 ENST00000361983.4
KIAA1279
KIAA1279
chr19_+_18718214 5.22 ENST00000600490.1
TMEM59L
transmembrane protein 59-like
chr14_+_100150622 5.19 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr1_-_149889382 5.13 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr5_-_176900610 4.90 ENST00000477391.2
ENST00000393565.1
ENST00000309007.5
DBN1
drebrin 1
chr20_-_36793774 4.82 ENST00000361475.2
TGM2
transglutaminase 2
chr10_+_17272608 4.82 ENST00000421459.2
VIM
vimentin
chr10_-_118764862 4.73 ENST00000260777.10
KIAA1598
KIAA1598
chr11_+_12132117 4.50 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr22_-_38669030 4.48 ENST00000361906.3
TMEM184B
transmembrane protein 184B
chr20_-_44539538 4.47 ENST00000372420.1
PLTP
phospholipid transfer protein
chr1_+_40506392 4.46 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr12_-_90102594 4.35 ENST00000428670.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr9_+_35732312 4.34 ENST00000353704.2
CREB3
cAMP responsive element binding protein 3
chr11_+_46402583 4.26 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr14_+_65879668 4.24 ENST00000553924.1
ENST00000358307.2
ENST00000557338.1
ENST00000554610.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr10_-_81205373 4.22 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr3_+_57994127 4.20 ENST00000490882.1
ENST00000295956.4
ENST00000358537.3
ENST00000429972.2
ENST00000348383.5
ENST00000357272.4
FLNB
filamin B, beta
chr1_-_95007193 4.12 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr5_+_138609782 4.11 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
MATR3
matrin 3
chr5_+_125758813 4.03 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr2_+_85132749 3.95 ENST00000233143.4
TMSB10
thymosin beta 10
chr7_+_95401851 3.88 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr5_-_172756506 3.85 ENST00000265087.4
STC2
stanniocalcin 2
chr1_+_155829286 3.83 ENST00000368324.4
SYT11
synaptotagmin XI
chr5_+_138609441 3.83 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3
matrin 3
chr9_-_113800317 3.82 ENST00000374431.3
LPAR1
lysophosphatidic acid receptor 1
chr14_+_105941118 3.82 ENST00000550577.1
ENST00000538259.2
CRIP2
cysteine-rich protein 2
chr12_-_52967600 3.76 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chr9_+_114423615 3.76 ENST00000374293.4
GNG10
guanine nucleotide binding protein (G protein), gamma 10
chr2_+_181845074 3.70 ENST00000602959.1
ENST00000602479.1
ENST00000392415.2
ENST00000602291.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr1_-_43833628 3.67 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr11_-_61735029 3.59 ENST00000526640.1
FTH1
ferritin, heavy polypeptide 1
chr3_-_48130314 3.57 ENST00000439356.1
ENST00000395734.3
ENST00000426837.2
MAP4
microtubule-associated protein 4
chr6_+_30850697 3.54 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr14_-_23822061 3.51 ENST00000397260.3
SLC22A17
solute carrier family 22, member 17
chr11_-_61734599 3.48 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr20_-_36793663 3.39 ENST00000536701.1
ENST00000536724.1
TGM2
transglutaminase 2
chr11_+_131781290 3.39 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr1_+_40505891 3.35 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr15_+_68871569 3.33 ENST00000566799.1
CORO2B
coronin, actin binding protein, 2B
chr7_-_80548667 3.32 ENST00000265361.3
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr16_+_6069664 3.24 ENST00000422070.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_+_95401877 3.23 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr2_+_181845298 3.22 ENST00000410062.4
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr10_+_47746929 3.20 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr10_+_48255253 3.19 ENST00000357718.4
ENST00000344416.5
ENST00000456111.2
ENST00000374258.3
ANXA8
AL591684.1
annexin A8
Protein LOC100996760
chr19_-_50143452 3.14 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr11_+_46402482 3.12 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr3_-_52567792 3.08 ENST00000307092.4
ENST00000422318.2
ENST00000459839.1
NT5DC2
5'-nucleotidase domain containing 2
chr12_-_109125285 3.03 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr9_-_35732362 3.01 ENST00000314888.9
ENST00000540444.1
TLN1
talin 1
chr9_+_19049372 2.93 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr2_+_201171372 2.92 ENST00000409140.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr10_-_47173994 2.90 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr1_-_26232522 2.87 ENST00000399728.1
STMN1
stathmin 1
chr16_+_8806800 2.86 ENST00000561870.1
ENST00000396600.2
ABAT
4-aminobutyrate aminotransferase
chr3_-_16555150 2.84 ENST00000334133.4
RFTN1
raftlin, lipid raft linker 1
chr17_-_61850894 2.75 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47
coiled-coil domain containing 47
chr19_-_19049791 2.74 ENST00000594439.1
ENST00000221222.11
HOMER3
homer homolog 3 (Drosophila)
chr7_-_55640176 2.68 ENST00000285279.5
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr22_-_45608324 2.64 ENST00000496226.1
ENST00000251993.7
KIAA0930
KIAA0930
chr1_-_113249734 2.60 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr14_-_103523745 2.57 ENST00000361246.2
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr18_+_9475001 2.54 ENST00000019317.4
RALBP1
ralA binding protein 1
chrX_+_47078069 2.52 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
CDK16
cyclin-dependent kinase 16
chr3_-_42845951 2.52 ENST00000418900.2
ENST00000430190.1
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr2_-_47168906 2.52 ENST00000444761.2
ENST00000409147.1
MCFD2
multiple coagulation factor deficiency 2
chr20_-_56285595 2.52 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_+_52776228 2.51 ENST00000256759.3
FST
follistatin
chr1_-_21948906 2.50 ENST00000374761.2
ENST00000599760.1
RAP1GAP
RAP1 GTPase activating protein
chr5_+_102595119 2.49 ENST00000510890.1
C5orf30
chromosome 5 open reading frame 30
chr20_-_36156293 2.45 ENST00000373537.2
ENST00000414542.2
BLCAP
bladder cancer associated protein
chr3_+_183415558 2.43 ENST00000305135.5
YEATS2
YEATS domain containing 2
chr1_+_44444865 2.38 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr1_-_113249678 2.35 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr8_-_144241432 2.33 ENST00000430474.2
LY6H
lymphocyte antigen 6 complex, locus H
chr2_+_220143989 2.31 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr17_+_2699697 2.25 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr2_-_200323414 2.25 ENST00000443023.1
SATB2
SATB homeobox 2
chr20_-_36156125 2.23 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr1_-_52456352 2.22 ENST00000371655.3
RAB3B
RAB3B, member RAS oncogene family
chr16_-_70719925 2.21 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr3_-_183735731 2.19 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr6_-_143266297 2.19 ENST00000367603.2
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr8_-_144241664 2.18 ENST00000342752.4
LY6H
lymphocyte antigen 6 complex, locus H
chr1_-_1009683 2.14 ENST00000453464.2
RNF223
ring finger protein 223
chr11_+_63742050 2.13 ENST00000314133.3
ENST00000535431.1
COX8A
AP000721.4
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr6_+_44238203 2.13 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr17_-_62658186 2.12 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr7_-_26240357 2.10 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr8_-_25315905 2.09 ENST00000221200.4
KCTD9
potassium channel tetramerization domain containing 9
chr1_+_44445549 2.08 ENST00000356836.6
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr1_-_23670817 2.06 ENST00000478691.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr19_+_7600584 2.06 ENST00000600737.1
PNPLA6
patatin-like phospholipase domain containing 6
chr14_+_31343747 2.00 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
COCH
cochlin
chr5_-_133340326 1.99 ENST00000425992.1
ENST00000395044.3
ENST00000395047.2
VDAC1
voltage-dependent anion channel 1
chr4_+_6271558 1.98 ENST00000503569.1
ENST00000226760.1
WFS1
Wolfram syndrome 1 (wolframin)
chr1_-_23670813 1.98 ENST00000374612.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr4_+_75480629 1.97 ENST00000380846.3
AREGB
amphiregulin B
chr7_+_73868120 1.93 ENST00000265755.3
GTF2IRD1
GTF2I repeat domain containing 1
chr9_-_113800341 1.92 ENST00000358883.4
LPAR1
lysophosphatidic acid receptor 1
chr12_-_124457371 1.91 ENST00000238156.3
ENST00000545037.1
CCDC92
coiled-coil domain containing 92
chr16_-_49698136 1.91 ENST00000535559.1
ZNF423
zinc finger protein 423
chr7_+_100273736 1.90 ENST00000412215.1
ENST00000393924.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr8_+_48920960 1.90 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr14_+_105331596 1.90 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
CEP170B
centrosomal protein 170B
chr11_-_45687128 1.88 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr19_+_45417812 1.84 ENST00000592535.1
APOC1
apolipoprotein C-I
chr19_+_7599597 1.82 ENST00000414982.3
ENST00000450331.3
PNPLA6
patatin-like phospholipase domain containing 6
chr20_-_3748416 1.81 ENST00000399672.1
C20orf27
chromosome 20 open reading frame 27
chr13_+_38923959 1.81 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr16_+_330581 1.80 ENST00000219409.3
ARHGDIG
Rho GDP dissociation inhibitor (GDI) gamma
chr1_+_202995611 1.78 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr1_+_15250596 1.75 ENST00000361144.5
KAZN
kazrin, periplakin interacting protein
chr10_+_94352956 1.74 ENST00000260731.3
KIF11
kinesin family member 11
chr2_+_239335449 1.72 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr2_+_173292280 1.72 ENST00000264107.7
ITGA6
integrin, alpha 6
chr2_+_220144052 1.71 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr22_-_28315115 1.70 ENST00000455418.3
ENST00000436663.1
ENST00000320996.10
ENST00000335272.5
PITPNB
phosphatidylinositol transfer protein, beta
chr21_-_34100244 1.69 ENST00000382491.3
ENST00000357345.3
ENST00000429236.1
SYNJ1
synaptojanin 1
chr9_-_131790464 1.67 ENST00000417224.1
ENST00000416629.1
ENST00000372559.1
SH3GLB2
SH3-domain GRB2-like endophilin B2
chr3_-_98312548 1.66 ENST00000264193.2
CPOX
coproporphyrinogen oxidase
chr1_-_150208498 1.65 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_113249948 1.64 ENST00000339083.7
ENST00000369642.3
RHOC
ras homolog family member C
chr2_-_47168850 1.62 ENST00000409207.1
MCFD2
multiple coagulation factor deficiency 2
chr11_-_3862206 1.60 ENST00000351018.4
RHOG
ras homolog family member G
chr14_+_31343951 1.60 ENST00000556908.1
ENST00000555881.1
ENST00000460581.2
COCH
cochlin
chr20_-_3748363 1.58 ENST00000217195.8
C20orf27
chromosome 20 open reading frame 27
chr16_+_90015105 1.54 ENST00000567999.1
ENST00000566079.1
ENST00000566820.1
ENST00000562578.1
ENST00000561741.1
ENST00000268676.7
ENST00000562986.1
ENST00000569453.1
ENST00000567884.1
ENST00000569061.1
ENST00000418391.2
ENST00000561959.1
ENST00000567874.1
ENST00000570182.1
ENST00000563795.1
DEF8
differentially expressed in FDCP 8 homolog (mouse)
chr17_-_65362678 1.54 ENST00000357146.4
ENST00000356126.3
PSMD12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr2_+_173600565 1.53 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_+_64081214 1.53 ENST00000542911.2
YTHDF3
YTH domain family, member 3
chr11_+_34938119 1.52 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX
pyruvate dehydrogenase complex, component X
chr2_+_173292390 1.51 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6
integrin, alpha 6
chr17_+_46126135 1.50 ENST00000361665.3
ENST00000585062.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr4_+_75310851 1.50 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr15_+_43809797 1.49 ENST00000399453.1
ENST00000300231.5
MAP1A
microtubule-associated protein 1A
chr20_+_17207665 1.47 ENST00000536609.1
PCSK2
proprotein convertase subtilisin/kexin type 2
chr2_+_173600514 1.46 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_48264816 1.46 ENST00000296435.2
ENST00000576243.1
CAMP
cathelicidin antimicrobial peptide
chr16_+_4674787 1.44 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr19_-_53662257 1.43 ENST00000599096.1
ENST00000334197.7
ENST00000597183.1
ENST00000601804.1
ENST00000601469.2
ENST00000452676.2
ZNF347
zinc finger protein 347
chr1_-_43232649 1.43 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
LEPRE1
leucine proline-enriched proteoglycan (leprecan) 1
chr8_+_64081118 1.41 ENST00000539294.1
YTHDF3
YTH domain family, member 3
chr21_+_45161301 1.40 ENST00000467908.1
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr4_+_75311019 1.40 ENST00000502307.1
AREG
amphiregulin
chrX_-_153599578 1.40 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr1_-_211752073 1.38 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr3_-_52001448 1.37 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4
poly(rC) binding protein 4
chr15_+_78832747 1.35 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr15_+_78833105 1.34 ENST00000558341.1
ENST00000559437.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr17_+_43972010 1.34 ENST00000334239.8
ENST00000446361.3
MAPT
microtubule-associated protein tau
chr2_+_173600671 1.33 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr20_+_17207636 1.32 ENST00000262545.2
PCSK2
proprotein convertase subtilisin/kexin type 2
chrX_+_48367338 1.31 ENST00000359882.4
ENST00000537758.1
ENST00000367574.4
ENST00000355961.4
ENST00000489940.1
ENST00000361988.3
PORCN
porcupine homolog (Drosophila)
chr12_-_56694142 1.31 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr1_-_155224751 1.30 ENST00000350210.2
ENST00000368368.3
FAM189B
family with sequence similarity 189, member B
chr19_-_6591113 1.29 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr2_+_182756701 1.28 ENST00000409001.1
SSFA2
sperm specific antigen 2
chr2_+_128403720 1.27 ENST00000272644.3
GPR17
G protein-coupled receptor 17
chr3_+_50273625 1.27 ENST00000536647.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr1_+_183155373 1.27 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr8_-_145018080 1.26 ENST00000354589.3
PLEC
plectin
chr17_+_61851157 1.25 ENST00000578681.1
ENST00000583590.1
DDX42
DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr2_-_73511559 1.23 ENST00000521871.1
FBXO41
F-box protein 41

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF148

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 19.4 GO:0048549 positive regulation of pinocytosis(GO:0048549)
3.2 28.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
2.7 8.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
2.4 7.1 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
2.3 13.8 GO:0030421 defecation(GO:0030421)
1.9 13.0 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.8 19.7 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.5 4.5 GO:0019417 sulfur oxidation(GO:0019417)
1.4 5.7 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.4 7.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.4 4.2 GO:0036071 N-glycan fucosylation(GO:0036071)
1.4 4.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.3 3.8 GO:1905154 negative regulation of membrane invagination(GO:1905154)
1.1 4.5 GO:0042360 vitamin E metabolic process(GO:0042360)
1.1 2.2 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
1.1 6.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
1.1 3.2 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
1.0 19.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.0 4.0 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.9 8.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.9 4.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.9 4.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.8 2.5 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.8 4.9 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.7 2.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.7 2.9 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.7 3.5 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.7 2.7 GO:1904978 regulation of endosome organization(GO:1904978)
0.6 3.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6 3.6 GO:0051012 microtubule sliding(GO:0051012)
0.6 2.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.6 3.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.6 2.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.6 14.5 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.6 1.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.6 2.8 GO:0030070 insulin processing(GO:0030070)
0.6 3.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.5 5.9 GO:0009414 response to water deprivation(GO:0009414)
0.5 16.0 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.5 2.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.5 5.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.5 5.5 GO:0033227 dsRNA transport(GO:0033227)
0.5 3.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.5 1.4 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.4 4.8 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.4 4.7 GO:0006983 ER overload response(GO:0006983)
0.4 2.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.4 3.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.4 3.2 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.4 7.6 GO:0006706 steroid catabolic process(GO:0006706)
0.4 6.1 GO:0051639 actin filament network formation(GO:0051639)
0.4 1.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.4 7.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.4 5.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4 1.1 GO:1900133 positive regulation of eosinophil degranulation(GO:0043311) regulation of renin secretion into blood stream(GO:1900133) positive regulation of eosinophil activation(GO:1902568)
0.4 1.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.3 2.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.3 4.4 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.3 1.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.3 8.0 GO:0061157 mRNA destabilization(GO:0061157)
0.3 3.0 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.3 5.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.3 5.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 0.9 GO:0019482 purine nucleobase catabolic process(GO:0006145) beta-alanine metabolic process(GO:0019482)
0.3 0.8 GO:0033212 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.3 1.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.3 0.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.3 1.8 GO:0071569 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 2.5 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.2 2.9 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 1.4 GO:0016479 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.2 6.5 GO:0035640 exploration behavior(GO:0035640)
0.2 2.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 0.7 GO:0048627 myoblast development(GO:0048627)
0.2 5.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 2.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 3.9 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 8.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 2.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 0.9 GO:0030047 actin modification(GO:0030047)
0.2 0.7 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
0.2 0.9 GO:0006041 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.2 1.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2 1.7 GO:0051597 response to methylmercury(GO:0051597)
0.2 1.1 GO:0051414 response to cortisol(GO:0051414)
0.2 1.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 6.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.2 1.1 GO:0090032 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.2 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 2.0 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 0.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 1.9 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.9 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 5.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 9.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.4 GO:0032900 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900)
0.1 1.5 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.1 6.7 GO:0051693 actin filament capping(GO:0051693)
0.1 2.5 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.4 GO:1904596 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.1 5.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.3 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.8 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 5.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 3.9 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 17.2 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 4.7 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 0.3 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 1.0 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 2.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 2.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 1.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 3.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.8 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.2 GO:0006449 regulation of translational termination(GO:0006449)
0.1 2.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 1.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.3 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 3.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.7 GO:0030539 male genitalia development(GO:0030539)
0.1 3.4 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.6 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.8 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 1.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.4 GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.1 3.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 5.3 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 13.4 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 1.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 1.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.6 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 1.1 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 1.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 3.6 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.9 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.0 0.2 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.7 GO:0010039 response to iron ion(GO:0010039)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0007015 actin filament organization(GO:0007015)
0.0 0.7 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 1.2 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 1.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.9 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 1.2 GO:0030888 regulation of B cell proliferation(GO:0030888)
0.0 3.3 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.7 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.0 GO:0006497 protein lipidation(GO:0006497)
0.0 0.4 GO:0042692 muscle cell differentiation(GO:0042692)
0.0 0.5 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.7 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.0 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
1.8 7.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.5 4.4 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
1.3 16.0 GO:0044327 dendritic spine head(GO:0044327)
1.1 16.9 GO:0033643 host cell part(GO:0033643)
1.0 3.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.7 2.9 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.7 19.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.6 1.9 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.5 2.9 GO:1990130 EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 1.4 GO:0031523 Myb complex(GO:0031523)
0.4 5.7 GO:0016600 flotillin complex(GO:0016600)
0.4 1.3 GO:0005607 laminin-2 complex(GO:0005607)
0.4 5.8 GO:0008091 spectrin(GO:0008091)
0.3 1.3 GO:0045298 tubulin complex(GO:0045298)
0.3 5.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 3.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 1.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 5.9 GO:0032585 multivesicular body membrane(GO:0032585)
0.3 16.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 2.6 GO:0042641 actomyosin(GO:0042641)
0.2 4.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 27.6 GO:0005882 intermediate filament(GO:0005882)
0.2 0.9 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 5.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 4.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 0.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 0.9 GO:0005726 perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061)
0.2 0.8 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 0.5 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.2 0.8 GO:0032021 NELF complex(GO:0032021)
0.2 2.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 2.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 29.8 GO:0043197 dendritic spine(GO:0043197)
0.2 1.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 2.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 4.4 GO:0005921 gap junction(GO:0005921)
0.1 0.9 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 5.4 GO:0031430 M band(GO:0031430)
0.1 0.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 7.3 GO:0014704 intercalated disc(GO:0014704)
0.1 0.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.8 GO:0071203 WASH complex(GO:0071203)
0.1 7.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 8.6 GO:0005802 trans-Golgi network(GO:0005802)
0.1 17.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.3 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.7 GO:0005903 brush border(GO:0005903)
0.1 5.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 2.4 GO:0042627 chylomicron(GO:0042627)
0.1 5.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 7.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 6.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.5 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.1 GO:0031143 pseudopodium(GO:0031143)
0.1 1.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 6.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.8 GO:0046930 pore complex(GO:0046930)
0.1 5.0 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.1 7.1 GO:0032432 actin filament bundle(GO:0032432)
0.1 8.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 1.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 5.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 3.6 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 1.7 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 37.1 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 2.0 GO:0045178 basal part of cell(GO:0045178)
0.1 7.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.7 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 3.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 2.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 20.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 3.1 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 6.4 GO:0030133 transport vesicle(GO:0030133)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.3 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.4 GO:0015030 Cajal body(GO:0015030)
0.0 2.0 GO:0070469 respiratory chain(GO:0070469)
0.0 1.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 3.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.6 GO:0030054 cell junction(GO:0030054)
0.0 1.9 GO:0043209 myelin sheath(GO:0043209)
0.0 1.0 GO:0005769 early endosome(GO:0005769)
0.0 1.1 GO:0030018 Z disc(GO:0030018)
0.0 0.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 13.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.4 8.6 GO:1990254 keratin filament binding(GO:1990254)
1.4 4.2 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
1.2 19.4 GO:0032036 myosin heavy chain binding(GO:0032036)
1.1 4.5 GO:0004461 lactose synthase activity(GO:0004461)
1.1 5.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
1.0 8.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.9 5.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7 12.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.7 16.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.7 2.9 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.7 3.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.7 2.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.7 5.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.6 5.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.6 3.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 7.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.5 5.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.5 7.1 GO:0045503 dynein light chain binding(GO:0045503)
0.5 6.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.4 8.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 1.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 0.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3 4.4 GO:0038132 neuregulin binding(GO:0038132)
0.3 1.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.3 1.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.3 2.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 4.9 GO:0005522 profilin binding(GO:0005522)
0.3 1.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.3 3.0 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 3.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 40.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 7.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 2.0 GO:0015288 porin activity(GO:0015288)
0.2 4.3 GO:0035497 cAMP response element binding(GO:0035497)
0.2 9.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 2.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 8.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 1.5 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 2.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 2.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 1.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.9 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.2 3.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 3.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 6.2 GO:0003785 actin monomer binding(GO:0003785)
0.2 5.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 19.6 GO:0005496 steroid binding(GO:0005496)
0.1 0.9 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 5.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.6 GO:0070097 delta-catenin binding(GO:0070097)
0.1 20.9 GO:0002020 protease binding(GO:0002020)
0.1 3.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.7 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 1.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 1.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.4 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.1 6.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 2.3 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.9 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 4.2 GO:0030552 cAMP binding(GO:0030552)
0.1 0.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 2.2 GO:0031489 myosin V binding(GO:0031489)
0.1 0.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.9 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 2.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.9 GO:0071949 FAD binding(GO:0071949)
0.1 5.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 7.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 1.4 GO:0031402 sodium ion binding(GO:0031402)
0.1 1.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 17.4 GO:0003924 GTPase activity(GO:0003924)
0.1 14.3 GO:0008017 microtubule binding(GO:0008017)
0.1 2.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.6 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.3 GO:0050699 WW domain binding(GO:0050699)
0.1 3.6 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 6.3 GO:0005178 integrin binding(GO:0005178)
0.1 9.3 GO:0008201 heparin binding(GO:0008201)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 8.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.8 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 2.9 GO:0015631 tubulin binding(GO:0015631)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 2.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 8.6 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 1.7 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 2.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.9 GO:0020037 heme binding(GO:0020037)
0.0 1.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.0 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 1.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 35.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2 5.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 6.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 8.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 4.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 12.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 19.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 7.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 5.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 6.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 7.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 6.2 PID AURORA B PATHWAY Aurora B signaling
0.1 1.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 3.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.1 ST STAT3 PATHWAY STAT3 Pathway
0.1 9.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 5.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 3.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 3.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 2.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 16.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 5.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 11.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.4 7.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 13.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 6.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 5.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 8.7 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.3 6.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.2 16.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 11.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 9.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 9.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 4.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 26.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 3.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 5.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 2.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 2.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 3.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 2.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 4.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 6.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 0.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 15.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 7.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 3.8 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.1 1.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 2.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 2.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 3.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway