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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for AACACUG

Z-value: 0.49

Motif logo

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miRNA associated with seed AACACUG

NamemiRBASE accession
hsa-miR-141-3p
MIMAT0000432
hsa-miR-200a-3p
MIMAT0000682

Activity profile of AACACUG motif

Sorted Z-values of AACACUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_51701924 12.17 ENST00000242719.3
RNF11
ring finger protein 11
chr3_+_62304712 11.38 ENST00000494481.1
C3orf14
chromosome 3 open reading frame 14
chr3_+_158991025 11.12 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr3_+_159557637 10.10 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chrX_-_13956737 9.57 ENST00000454189.2
GPM6B
glycoprotein M6B
chr6_-_18265050 8.31 ENST00000397239.3
DEK
DEK oncogene
chr1_-_6453399 8.06 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr1_+_84543734 7.82 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_8534067 7.61 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr3_-_33686743 7.54 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr7_-_47621736 6.97 ENST00000311160.9
TNS3
tensin 3
chr5_+_82767284 6.65 ENST00000265077.3
VCAN
versican
chr1_-_150208291 6.62 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_211752073 6.48 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr13_+_98605902 6.27 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5
importin 5
chr5_+_145826867 6.24 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr8_+_20054878 5.73 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr6_-_122792919 5.58 ENST00000339697.4
SERINC1
serine incorporator 1
chr1_+_36621529 5.48 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr15_+_52311398 5.32 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr8_+_48920960 5.29 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr2_-_2334888 5.15 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr1_+_40723779 5.01 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr1_-_11120057 4.93 ENST00000376957.2
SRM
spermidine synthase
chr12_-_109125285 4.87 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr8_+_30013813 4.84 ENST00000221114.3
DCTN6
dynactin 6
chr13_+_42846272 4.78 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr2_-_131850951 4.69 ENST00000409185.1
ENST00000389915.3
FAM168B
family with sequence similarity 168, member B
chr2_+_102508955 4.57 ENST00000414004.2
FLJ20373
FLJ20373
chr6_-_16761678 4.55 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr7_-_111846435 4.49 ENST00000437633.1
ENST00000428084.1
DOCK4
dedicator of cytokinesis 4
chr5_-_133561752 4.47 ENST00000519718.1
ENST00000481195.1
CTD-2410N18.5
PPP2CA
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr6_+_107811162 4.47 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr8_+_26149007 4.44 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr17_+_11924129 4.44 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr16_+_53088885 4.40 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_+_35840542 4.32 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr11_+_86748863 4.30 ENST00000340353.7
TMEM135
transmembrane protein 135
chr17_-_46178527 4.30 ENST00000393408.3
CBX1
chromobox homolog 1
chr17_+_40118759 4.29 ENST00000393892.3
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr4_-_100871506 4.08 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr3_+_113465866 4.03 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chrX_+_51928002 4.02 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chr11_-_115375107 3.95 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr2_-_37899323 3.90 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr20_+_3776371 3.90 ENST00000245960.5
CDC25B
cell division cycle 25B
chr15_+_57210818 3.77 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr4_-_100815525 3.76 ENST00000226522.8
ENST00000499666.2
LAMTOR3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr3_-_195808952 3.68 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chr5_-_11904152 3.64 ENST00000304623.8
ENST00000458100.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr6_+_64281906 3.42 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chrX_+_118370211 3.41 ENST00000217971.7
PGRMC1
progesterone receptor membrane component 1
chr9_-_6015607 3.34 ENST00000259569.5
RANBP6
RAN binding protein 6
chr6_+_17600576 3.34 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr17_+_66508537 3.20 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr5_+_112312416 3.12 ENST00000389063.2
DCP2
decapping mRNA 2
chr6_-_52441713 3.10 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr1_+_93913713 3.09 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr16_-_71758602 3.07 ENST00000568954.1
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr21_-_15755446 3.02 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr19_+_19322758 2.99 ENST00000252575.6
NCAN
neurocan
chr8_-_67525473 2.88 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr2_+_178257372 2.88 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr1_-_16482554 2.87 ENST00000358432.5
EPHA2
EPH receptor A2
chr1_-_243418344 2.86 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr1_-_225840747 2.84 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr12_+_48516357 2.82 ENST00000549022.1
ENST00000547587.1
ENST00000312352.7
PFKM
phosphofructokinase, muscle
chr6_-_10415470 2.77 ENST00000379604.2
ENST00000379613.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr13_-_50367057 2.76 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr20_+_10199468 2.75 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr5_+_10353780 2.74 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr9_+_130374537 2.70 ENST00000373302.3
ENST00000373299.1
STXBP1
syntaxin binding protein 1
chr1_-_212004090 2.70 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr5_-_132073210 2.61 ENST00000378735.1
ENST00000378746.4
KIF3A
kinesin family member 3A
chr3_+_61547585 2.61 ENST00000295874.10
ENST00000474889.1
PTPRG
protein tyrosine phosphatase, receptor type, G
chr3_-_185542817 2.58 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr7_+_73703728 2.56 ENST00000361545.5
ENST00000223398.6
CLIP2
CAP-GLY domain containing linker protein 2
chr2_+_169312350 2.53 ENST00000305747.6
CERS6
ceramide synthase 6
chr2_+_113403434 2.50 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr14_-_57735528 2.48 ENST00000340918.7
ENST00000413566.2
EXOC5
exocyst complex component 5
chr7_+_107220422 2.44 ENST00000005259.4
BCAP29
B-cell receptor-associated protein 29
chr17_-_41856305 2.41 ENST00000397937.2
ENST00000226004.3
DUSP3
dual specificity phosphatase 3
chr10_+_93558069 2.40 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr20_-_57617831 2.37 ENST00000371033.5
ENST00000355937.4
SLMO2
slowmo homolog 2 (Drosophila)
chr18_+_29171689 2.33 ENST00000237014.3
TTR
transthyretin
chr2_-_152684977 2.30 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr1_+_200708671 2.29 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr3_-_125313934 2.29 ENST00000296220.5
OSBPL11
oxysterol binding protein-like 11
chr11_+_114270752 2.26 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr1_+_218458625 2.24 ENST00000366932.3
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr4_-_69215699 2.18 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr2_+_29117509 2.17 ENST00000407426.3
WDR43
WD repeat domain 43
chr1_+_50574585 2.17 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr15_+_77712993 2.16 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr14_-_103523745 2.13 ENST00000361246.2
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr1_+_29063271 2.12 ENST00000373812.3
YTHDF2
YTH domain family, member 2
chr5_+_138629417 2.12 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3
matrin 3
chr17_+_49230897 2.10 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME1
NME1-NME2
NME2
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr13_-_31038370 2.10 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr5_+_177631497 2.10 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr3_+_152017181 2.08 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr11_-_117186946 2.06 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1
chrX_+_40944871 2.06 ENST00000378308.2
ENST00000324545.8
USP9X
ubiquitin specific peptidase 9, X-linked
chr3_-_72496035 2.06 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr4_-_76598296 2.04 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr14_+_61201445 2.03 ENST00000261245.4
ENST00000539616.2
MNAT1
MNAT CDK-activating kinase assembly factor 1
chr15_-_25684110 2.02 ENST00000232165.3
UBE3A
ubiquitin protein ligase E3A
chr17_+_46985731 2.01 ENST00000360943.5
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr5_+_169010638 1.99 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr22_-_28197486 1.98 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr3_+_132136331 1.97 ENST00000260818.6
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr3_+_171758344 1.97 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chrX_-_137793826 1.94 ENST00000315930.6
FGF13
fibroblast growth factor 13
chr1_-_205719295 1.93 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr14_-_64010046 1.91 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr5_-_43313574 1.91 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr13_-_53422640 1.89 ENST00000338862.4
ENST00000377942.3
PCDH8
protocadherin 8
chr12_-_46766577 1.89 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chrX_-_51812268 1.89 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
MAGED4B
melanoma antigen family D, 4B
chr16_-_20911641 1.88 ENST00000564349.1
ENST00000324344.4
ERI2
DCUN1D3
ERI1 exoribonuclease family member 2
DCN1, defective in cullin neddylation 1, domain containing 3
chr12_+_12938541 1.86 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr4_+_183164574 1.84 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr12_-_76478686 1.81 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_93811438 1.81 ENST00000370272.4
ENST00000370267.1
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr1_+_244214577 1.80 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr6_+_71998506 1.78 ENST00000370435.4
OGFRL1
opioid growth factor receptor-like 1
chr6_-_132834184 1.75 ENST00000367941.2
ENST00000367937.4
STX7
syntaxin 7
chr7_+_129710350 1.75 ENST00000335420.5
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr10_-_81205373 1.74 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr4_+_113970772 1.74 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr5_-_146833485 1.72 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr17_-_4269768 1.71 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr14_+_97263641 1.69 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr20_-_524455 1.69 ENST00000349736.5
ENST00000217244.3
CSNK2A1
casein kinase 2, alpha 1 polypeptide
chr5_-_132113036 1.68 ENST00000378706.1
SEPT8
septin 8
chr9_+_110045537 1.67 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr15_-_37390482 1.66 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr5_+_179125907 1.66 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
CANX
calnexin
chr15_-_52821247 1.65 ENST00000399231.3
ENST00000399233.2
MYO5A
myosin VA (heavy chain 12, myoxin)
chr3_+_187930719 1.65 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_218519577 1.65 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr6_-_86352642 1.65 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr3_-_160283348 1.64 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr9_-_74980113 1.64 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr12_+_96588143 1.62 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr3_-_55523966 1.62 ENST00000474267.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr7_-_108096822 1.62 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule
chr9_+_32384617 1.57 ENST00000379923.1
ENST00000309951.6
ENST00000541043.1
ACO1
aconitase 1, soluble
chr2_+_30369807 1.57 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
YPEL5
yippee-like 5 (Drosophila)
chr17_-_73389737 1.57 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chr1_-_35658736 1.55 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr11_-_87908600 1.54 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr10_+_31608054 1.54 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr12_+_110719032 1.53 ENST00000395494.2
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr9_+_112810878 1.52 ENST00000434623.2
ENST00000374525.1
AKAP2
A kinase (PRKA) anchor protein 2
chr7_-_151217001 1.52 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr11_+_101981169 1.52 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1
Yes-associated protein 1
chr10_-_71930222 1.44 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1A
SAR1 homolog A (S. cerevisiae)
chr6_+_155054459 1.43 ENST00000367178.3
ENST00000417268.1
ENST00000367186.4
SCAF8
SR-related CTD-associated factor 8
chr2_-_161350305 1.41 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr8_-_95908902 1.40 ENST00000520509.1
CCNE2
cyclin E2
chr9_+_112542572 1.38 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr1_+_39456895 1.36 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr5_+_118407053 1.34 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr2_-_50574856 1.33 ENST00000342183.5
NRXN1
neurexin 1
chr3_-_56502375 1.32 ENST00000288221.6
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr13_+_25946201 1.30 ENST00000381655.2
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr7_+_128379346 1.29 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr1_-_23670817 1.29 ENST00000478691.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr15_+_41523335 1.28 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chr8_+_136469684 1.27 ENST00000355849.5
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr2_+_71558858 1.26 ENST00000437658.2
ENST00000355812.3
ENST00000377802.2
ENST00000264447.4
ENST00000409544.1
ENST00000455226.1
ENST00000454278.1
ENST00000417778.1
ENST00000454122.1
ZNF638
zinc finger protein 638
chr22_-_22221900 1.25 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr5_-_168006591 1.23 ENST00000239231.6
PANK3
pantothenate kinase 3
chr2_-_9143786 1.19 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr16_-_69368774 1.19 ENST00000562949.1
RP11-343C2.12
Conserved oligomeric Golgi complex subunit 8
chr12_-_16761007 1.18 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_+_96931834 1.18 ENST00000488633.1
CIAO1
cytosolic iron-sulfur protein assembly 1
chr7_-_79082867 1.17 ENST00000419488.1
ENST00000354212.4
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_55014415 1.16 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1
lysophospholipase I
chr2_+_5832799 1.16 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr5_+_65440032 1.14 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr5_-_148930960 1.14 ENST00000261798.5
ENST00000377843.2
CSNK1A1
casein kinase 1, alpha 1
chr18_-_21977748 1.12 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr18_+_60382672 1.10 ENST00000400316.4
ENST00000262719.5
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr3_+_19988566 1.10 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr3_+_39851094 1.09 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr1_-_173886491 1.07 ENST00000367698.3
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr1_-_231560790 1.06 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr1_+_110162448 1.06 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
AMPD2
adenosine monophosphate deaminase 2
chr17_+_57642886 1.05 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr17_-_38804061 1.05 ENST00000474246.1
ENST00000377808.4
ENST00000578044.1
ENST00000580419.1
ENST00000400122.3
ENST00000580654.1
ENST00000577721.1
ENST00000478349.2
ENST00000431889.2
SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr17_+_68165657 1.04 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr22_-_28315115 1.03 ENST00000455418.3
ENST00000436663.1
ENST00000320996.10
ENST00000335272.5
PITPNB
phosphatidylinositol transfer protein, beta
chr2_+_160568978 1.02 ENST00000409175.1
ENST00000539065.1
ENST00000259050.4
ENST00000421037.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr4_+_160188889 1.01 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr10_-_62704005 1.00 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr10_-_65225722 0.98 ENST00000399251.1
JMJD1C
jumonji domain containing 1C
chr1_-_175712829 0.94 ENST00000367674.2
TNR
tenascin R
chr5_+_174905398 0.94 ENST00000321442.5
SFXN1
sideroflexin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of AACACUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0021678 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
2.0 8.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
1.7 5.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
1.6 7.8 GO:0097338 response to clozapine(GO:0097338)
1.5 4.4 GO:0072709 cellular response to sorbitol(GO:0072709)
1.3 6.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
1.0 3.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.0 2.9 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.0 2.9 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
1.0 9.6 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.9 1.9 GO:0032328 alanine transport(GO:0032328)
0.9 2.8 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.9 2.7 GO:0007412 axon target recognition(GO:0007412) regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.9 4.5 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.9 2.6 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.9 4.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.8 7.5 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.8 1.6 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.8 2.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.8 8.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.7 2.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.7 4.9 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.7 2.8 GO:0003409 optic cup structural organization(GO:0003409)
0.6 9.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.6 1.7 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 2.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.5 10.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.5 2.1 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.5 1.6 GO:0010040 response to iron(II) ion(GO:0010040)
0.5 1.5 GO:1903233 T-tubule organization(GO:0033292) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.5 2.0 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.5 4.9 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.5 1.9 GO:0019046 release from viral latency(GO:0019046)
0.5 5.6 GO:0015825 L-serine transport(GO:0015825)
0.4 3.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.4 3.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.4 2.6 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.4 1.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.4 2.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4 1.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.4 3.9 GO:0007144 female meiosis I(GO:0007144)
0.4 5.8 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.4 1.9 GO:1990834 response to odorant(GO:1990834)
0.4 1.2 GO:0061386 closure of optic fissure(GO:0061386)
0.4 1.5 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 1.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.3 8.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 11.3 GO:0090383 phagosome acidification(GO:0090383)
0.3 2.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 4.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 2.1 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.3 1.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.3 1.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 1.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 2.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.3 1.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 1.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.3 2.0 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 2.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.3 1.8 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.2 0.7 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.2 2.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 1.2 GO:0002084 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2 0.7 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.2 3.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.2 3.7 GO:0033572 transferrin transport(GO:0033572)
0.2 2.1 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.2 0.8 GO:0035973 aggrephagy(GO:0035973)
0.2 4.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 5.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.2 1.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 1.5 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.2 0.9 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 0.6 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 11.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 0.9 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.2 2.8 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.2 1.1 GO:0051036 regulation of endosome size(GO:0051036)
0.2 2.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 1.1 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 2.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 2.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.1 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.2 1.9 GO:0009642 response to light intensity(GO:0009642)
0.2 4.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.2 1.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.2 1.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 0.5 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 2.7 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.2 2.0 GO:0007512 adult heart development(GO:0007512)
0.2 1.9 GO:0042118 endothelial cell activation(GO:0042118)
0.2 0.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 5.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 6.6 GO:0043486 histone exchange(GO:0043486)
0.1 4.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 1.8 GO:0097264 self proteolysis(GO:0097264)
0.1 1.1 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 2.0 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253) stress granule assembly(GO:0034063)
0.1 1.9 GO:0045116 protein neddylation(GO:0045116)
0.1 4.3 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.1 0.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.7 GO:0010606 regulation of cytoplasmic mRNA processing body assembly(GO:0010603) positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.8 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.5 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 1.1 GO:0032264 IMP salvage(GO:0032264)
0.1 0.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 2.2 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.4 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 0.6 GO:0021764 amygdala development(GO:0021764)
0.1 2.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151) phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 0.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 1.7 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 5.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 2.2 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.7 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1 0.9 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.3 GO:0048665 neuron fate specification(GO:0048665)
0.1 2.8 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 0.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.5 GO:0040029 regulation of gene expression, epigenetic(GO:0040029)
0.1 3.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 2.6 GO:0051028 mRNA transport(GO:0051028)
0.1 2.8 GO:0090102 cochlea development(GO:0090102)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 1.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 2.2 GO:0048286 lung alveolus development(GO:0048286)
0.1 0.6 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 1.7 GO:0016577 histone demethylation(GO:0016577)
0.1 1.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.6 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.3 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.1 6.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.4 GO:0007129 synapsis(GO:0007129)
0.0 2.1 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.7 GO:0008542 visual learning(GO:0008542)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 1.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 1.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.0 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.6 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.7 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.6 GO:0001764 neuron migration(GO:0001764)
0.0 2.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.6 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 1.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.9 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.7 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 1.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.7 GO:0045445 myoblast differentiation(GO:0045445)
0.0 1.2 GO:0021766 hippocampus development(GO:0021766)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 3.4 GO:0051168 nuclear export(GO:0051168)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 1.6 GO:0048675 axon extension(GO:0048675)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.5 GO:0001756 somitogenesis(GO:0001756)
0.0 0.3 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.9 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.0 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
1.5 7.6 GO:0097513 myosin II filament(GO:0097513)
0.9 4.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.9 4.3 GO:0001940 male pronucleus(GO:0001940)
0.8 7.5 GO:0045180 basal cortex(GO:0045180)
0.8 3.8 GO:0071986 Ragulator complex(GO:0071986)
0.8 9.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.7 2.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.7 4.1 GO:0001740 Barr body(GO:0001740)
0.7 2.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.7 2.6 GO:0016939 kinesin II complex(GO:0016939)
0.6 2.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 11.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.5 2.7 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.4 1.3 GO:0043291 RAVE complex(GO:0043291)
0.4 9.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.4 1.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.3 4.8 GO:0005869 dynactin complex(GO:0005869)
0.3 6.6 GO:0000812 Swr1 complex(GO:0000812)
0.3 0.9 GO:0072534 perineuronal net(GO:0072534)
0.3 1.5 GO:0031905 early endosome lumen(GO:0031905)
0.3 3.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 1.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.3 1.6 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.3 4.3 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.2 1.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 7.4 GO:1990752 microtubule end(GO:1990752)
0.2 7.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 1.6 GO:0097452 GAIT complex(GO:0097452)
0.2 0.7 GO:0005879 axonemal microtubule(GO:0005879)
0.2 7.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.4 GO:0000145 exocyst(GO:0000145)
0.2 1.2 GO:0071817 MMXD complex(GO:0071817)
0.2 3.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 1.6 GO:0042382 paraspeckles(GO:0042382)
0.2 3.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.2 GO:0071203 WASH complex(GO:0071203)
0.2 2.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 2.0 GO:0005675 holo TFIIH complex(GO:0005675)
0.2 2.0 GO:0097470 ribbon synapse(GO:0097470)
0.1 1.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.8 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 1.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 4.5 GO:0032420 stereocilium(GO:0032420)
0.1 1.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 2.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.7 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 1.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 4.2 GO:0001772 immunological synapse(GO:0001772)
0.1 1.6 GO:0043194 axon initial segment(GO:0043194)
0.1 6.9 GO:0030315 T-tubule(GO:0030315)
0.1 1.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 10.6 GO:0005643 nuclear pore(GO:0005643)
0.1 7.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 6.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 6.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 13.4 GO:0055037 recycling endosome(GO:0055037)
0.1 0.8 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 2.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 2.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 9.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 3.5 GO:0030426 growth cone(GO:0030426)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 4.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.1 GO:0042641 actomyosin(GO:0042641)
0.1 17.8 GO:0005819 spindle(GO:0005819)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0071564 npBAF complex(GO:0071564)
0.0 2.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 6.9 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 5.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 2.6 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 3.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 7.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 2.3 GO:0000502 proteasome complex(GO:0000502)
0.0 2.8 GO:0030175 filopodium(GO:0030175)
0.0 2.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 3.2 GO:0035579 specific granule membrane(GO:0035579)
0.0 3.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.5 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 3.1 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0035061 Smc5-Smc6 complex(GO:0030915) interchromatin granule(GO:0035061)
0.0 1.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.3 GO:0043204 perikaryon(GO:0043204)
0.0 3.6 GO:0043292 contractile fiber(GO:0043292)
0.0 0.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 4.0 GO:0005938 cell cortex(GO:0005938)
0.0 1.4 GO:0042383 sarcolemma(GO:0042383)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.6 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0004766 spermidine synthase activity(GO:0004766)
1.5 4.5 GO:0032184 SUMO polymer binding(GO:0032184)
1.2 3.7 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.9 4.5 GO:0034046 poly(G) binding(GO:0034046)
0.8 8.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.7 2.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.7 2.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.6 2.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.5 1.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.5 1.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 1.6 GO:0051538 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.5 2.0 GO:0043515 kinetochore binding(GO:0043515)
0.5 7.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 3.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.5 4.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.5 2.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.5 5.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 2.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.4 6.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.4 1.7 GO:0031493 nucleosomal histone binding(GO:0031493)
0.4 2.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.4 10.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 1.5 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.4 1.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.4 13.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 2.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.3 9.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 3.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.3 4.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 7.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 9.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 2.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.3 6.6 GO:0004707 MAP kinase activity(GO:0004707)
0.3 2.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 4.4 GO:0048156 tau protein binding(GO:0048156)
0.3 5.5 GO:0050811 GABA receptor binding(GO:0050811)
0.3 2.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.7 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2 4.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 7.8 GO:0070064 proline-rich region binding(GO:0070064)
0.2 2.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 2.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 3.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 1.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 9.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 0.8 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 2.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 5.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 3.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 3.8 GO:0035497 cAMP response element binding(GO:0035497)
0.2 4.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 9.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.7 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 6.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 0.7 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.1 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.1 1.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 5.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.7 GO:0000146 microfilament motor activity(GO:0000146)
0.1 2.9 GO:0071949 FAD binding(GO:0071949)
0.1 1.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.9 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 2.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 2.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.2 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 2.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.6 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.5 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 2.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 4.3 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.1 2.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.5 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 2.8 GO:0050699 WW domain binding(GO:0050699)
0.1 1.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 2.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 5.8 GO:0032947 protein complex scaffold(GO:0032947)
0.1 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 1.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.8 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 3.6 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 1.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 3.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.4 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 3.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 4.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 8.3 GO:0005525 GTP binding(GO:0005525)
0.0 1.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.8 GO:0042393 histone binding(GO:0042393)
0.0 3.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.0 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 3.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 4.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 6.8 PID IL3 PATHWAY IL3-mediated signaling events
0.1 3.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 9.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 6.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 1.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.3 PID FOXO PATHWAY FoxO family signaling
0.0 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.4 13.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.4 6.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 9.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 11.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 6.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 3.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 5.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 4.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 3.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 7.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 4.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 4.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 4.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.6 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 4.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 4.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 7.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 4.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 4.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 6.3 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 4.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 1.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 2.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion