Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for AAGGUGC
Z-value: 0.15
Motif logo
miRNA associated with seed AAGGUGC
Network of associatons between targets according to the STRING database.
First level regulatory network of AAGGUGC
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.5 | GO:0043090 | amino acid import(GO:0043090) |
| 1.0 | 8.4 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.0 | 6.3 | GO:0060348 | bone development(GO:0060348) |
| 1.6 | 4.7 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 0.0 | 4.7 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.1 | 4.6 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 4.4 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.8 | 4.2 | GO:0030047 | actin modification(GO:0030047) |
| 0.0 | 4.0 | GO:0045930 | negative regulation of mitotic cell cycle(GO:0045930) |
| 1.2 | 3.7 | GO:0002605 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 8.4 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 5.3 | GO:0005819 | spindle(GO:0005819) |
| 0.1 | 4.7 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.2 | 4.4 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.3 | 3.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 3.5 | GO:0030496 | midbody(GO:0030496) |
| 0.1 | 2.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 2.4 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 2.3 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.2 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.3 | 8.5 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 1.7 | 8.4 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.0 | 4.6 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 4.4 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.7 | 4.2 | GO:0038049 | transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) |
| 0.1 | 4.2 | GO:0019003 | GDP binding(GO:0019003) |
| 1.2 | 3.7 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.3 | 3.3 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.0 | 2.9 | GO:0017048 | Rho GTPase binding(GO:0017048) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 4.7 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 4.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 2.7 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 2.5 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 2.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.6 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 1.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 1.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.4 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 4.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 4.2 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 3.7 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 2.5 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 2.4 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 2.1 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 1.9 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 1.8 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 1.5 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |