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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for AAUGCCC

Z-value: 0.23

Motif logo

miRNA associated with seed AAUGCCC

NamemiRBASE accession
MIMAT0000710
MIMAT0022834

Activity profile of AAUGCCC motif

Sorted Z-values of AAUGCCC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_153574480 1.62 ENST00000410080.1
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr3_+_23986748 1.61 ENST00000312521.4
nuclear receptor subfamily 1, group D, member 2
chr21_-_28217721 1.46 ENST00000284984.3
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr3_-_55523966 1.37 ENST00000474267.1
wingless-type MMTV integration site family, member 5A
chr3_-_33481835 1.34 ENST00000283629.3
upstream binding protein 1 (LBP-1a)
chr3_+_113775576 1.15 ENST00000485050.1
ENST00000281273.4
queuine tRNA-ribosyltransferase domain containing 1
chr12_-_15942309 1.08 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
epidermal growth factor receptor pathway substrate 8
chr12_+_72666407 0.99 ENST00000261180.4
thyrotropin-releasing hormone degrading enzyme
chr17_-_78009647 0.94 ENST00000310924.2
TBC1 domain family, member 16
chr12_+_66217911 0.91 ENST00000403681.2
high mobility group AT-hook 2
chr19_+_46850251 0.88 ENST00000012443.4
protein phosphatase 5, catalytic subunit
chr5_+_112312416 0.87 ENST00000389063.2
decapping mRNA 2
chr12_+_68042495 0.82 ENST00000344096.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr1_+_2160134 0.81 ENST00000378536.4
v-ski avian sarcoma viral oncogene homolog
chr4_-_74124502 0.81 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ankyrin repeat domain 17
chr16_+_67063036 0.80 ENST00000290858.6
ENST00000564034.1
core-binding factor, beta subunit
chr9_-_14314066 0.77 ENST00000397575.3
nuclear factor I/B
chr3_+_171758344 0.73 ENST00000336824.4
ENST00000423424.1
fibronectin type III domain containing 3B
chr6_-_134639180 0.72 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr1_-_22109682 0.71 ENST00000400301.1
ENST00000532737.1
ubiquitin specific peptidase 48
chr9_-_117880477 0.71 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
tenascin C
chr9_+_114659046 0.66 ENST00000374279.3
UDP-glucose ceramide glucosyltransferase
chr3_-_79068594 0.66 ENST00000436010.2
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr12_-_31479045 0.65 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr3_-_113465065 0.64 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr3_-_123603137 0.63 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
myosin light chain kinase
chr11_-_31839488 0.63 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
paired box 6
chrX_-_109561294 0.61 ENST00000372059.2
ENST00000262844.5
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr2_-_64881018 0.61 ENST00000313349.3
SERTA domain containing 2
chr1_-_153588334 0.59 ENST00000476873.1
S100 calcium binding protein A14
chrX_+_77359671 0.59 ENST00000373316.4
phosphoglycerate kinase 1
chr1_-_155881156 0.55 ENST00000539040.1
ENST00000368323.3
Ras-like without CAAX 1
chr6_-_111804393 0.55 ENST00000368802.3
ENST00000368805.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr3_-_47823298 0.51 ENST00000254480.5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr5_-_43313574 0.51 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr2_-_208634287 0.50 ENST00000295417.3
frizzled family receptor 5
chr16_+_53088885 0.50 ENST00000566029.1
ENST00000447540.1
chromodomain helicase DNA binding protein 9
chr5_+_133861790 0.49 ENST00000395003.1
jade family PHD finger 2
chr2_-_183903133 0.48 ENST00000361354.4
NCK-associated protein 1
chr12_-_75905374 0.48 ENST00000438169.2
ENST00000229214.4
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr2_+_46926048 0.47 ENST00000306503.5
suppressor of cytokine signaling 5
chr10_-_98346801 0.47 ENST00000371142.4
transmembrane 9 superfamily member 3
chr2_-_200322723 0.46 ENST00000417098.1
SATB homeobox 2
chr5_+_74632993 0.46 ENST00000287936.4
3-hydroxy-3-methylglutaryl-CoA reductase
chr1_-_205719295 0.43 ENST00000367142.4
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr15_+_96873921 0.41 ENST00000394166.3
nuclear receptor subfamily 2, group F, member 2
chr1_-_244013384 0.40 ENST00000366539.1
v-akt murine thymoma viral oncogene homolog 3
chr9_+_131445928 0.39 ENST00000372692.4
SET nuclear oncogene
chr7_-_27205136 0.38 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr11_+_2466218 0.38 ENST00000155840.5
potassium voltage-gated channel, KQT-like subfamily, member 1
chr20_+_56884752 0.37 ENST00000244040.3
RAB22A, member RAS oncogene family
chr8_+_54764346 0.36 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr7_-_32931387 0.36 ENST00000304056.4
kelch repeat and BTB (POZ) domain containing 2
chr14_+_55518349 0.35 ENST00000395468.4
mitogen-activated protein kinase 1 interacting protein 1-like
chr8_-_57123815 0.35 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr1_+_36396677 0.33 ENST00000373191.4
ENST00000397828.2
argonaute RISC catalytic component 3
chr1_-_38325256 0.33 ENST00000373036.4
metal-regulatory transcription factor 1
chr11_-_27528301 0.33 ENST00000524596.1
ENST00000278193.2
lin-7 homolog C (C. elegans)
chr12_+_56137064 0.31 ENST00000257868.5
ENST00000546799.1
growth differentiation factor 11
chr7_+_138145076 0.30 ENST00000343526.4
tripartite motif containing 24
chrX_+_23352133 0.29 ENST00000379361.4
patched domain containing 1
chr11_+_64073699 0.29 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr10_+_22610124 0.29 ENST00000376663.3
BMI1 polycomb ring finger oncogene
chr3_-_15901278 0.28 ENST00000399451.2
ankyrin repeat domain 28
chr18_-_60987220 0.28 ENST00000398117.1
B-cell CLL/lymphoma 2
chr3_-_125094093 0.28 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
zinc finger protein 148
chr7_-_83824169 0.27 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_11762202 0.26 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
vestigial like 4 (Drosophila)
chr19_-_49576198 0.25 ENST00000221444.1
potassium voltage-gated channel, shaker-related subfamily, member 7
chr11_+_34642656 0.25 ENST00000257831.3
ENST00000450654.2
ets homologous factor
chr17_-_16118835 0.24 ENST00000582357.1
ENST00000436828.1
ENST00000411510.1
ENST00000268712.3
nuclear receptor corepressor 1
chr1_+_29063271 0.24 ENST00000373812.3
YTH domain family, member 2
chr10_-_105615164 0.23 ENST00000355946.2
ENST00000369774.4
SH3 and PX domains 2A
chr15_+_52121822 0.23 ENST00000558455.1
ENST00000308580.7
tropomodulin 3 (ubiquitous)
chr4_+_38665810 0.23 ENST00000261438.5
ENST00000514033.1
Kruppel-like factor 3 (basic)
chr3_+_51575596 0.22 ENST00000409535.2
RAD54-like 2 (S. cerevisiae)
chr3_-_48885228 0.22 ENST00000454963.1
ENST00000296446.8
ENST00000419216.1
ENST00000265563.8
protein kinase, cAMP-dependent, regulatory, type II, alpha
chr11_-_77532050 0.22 ENST00000308488.6
remodeling and spacing factor 1
chr11_-_57283159 0.21 ENST00000533263.1
ENST00000278426.3
solute carrier family 43 (amino acid system L transporter), member 1
chr16_+_70557685 0.19 ENST00000302516.5
ENST00000566095.2
ENST00000577085.1
ENST00000567654.1
splicing factor 3b, subunit 3, 130kDa
chr2_-_157189180 0.19 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
nuclear receptor subfamily 4, group A, member 2
chr2_+_131862900 0.19 ENST00000438882.2
ENST00000538982.1
ENST00000404460.1
pleckstrin homology domain containing, family B (evectins) member 2
chr21_+_38071430 0.18 ENST00000290399.6
single-minded family bHLH transcription factor 2
chr18_+_56338618 0.17 ENST00000348428.3
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr17_+_28804380 0.16 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
golgi SNAP receptor complex member 1
chr17_-_56084578 0.16 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
serine/arginine-rich splicing factor 1
chr13_-_21476900 0.15 ENST00000400602.2
ENST00000255305.6
exportin 4
chr1_-_78225482 0.15 ENST00000524778.1
ENST00000370794.3
ENST00000370793.1
ENST00000370792.3
ubiquitin specific peptidase 33
chr2_+_192542850 0.15 ENST00000410026.2
nucleic acid binding protein 1
chr7_+_139044621 0.15 ENST00000354926.4
C7orf55-LUC7L2 readthrough
chrX_-_3631635 0.14 ENST00000262848.5
protein kinase, X-linked
chr1_-_155211017 0.14 ENST00000536770.1
ENST00000368373.3
glucosidase, beta, acid
chr7_-_151217001 0.14 ENST00000262187.5
Ras homolog enriched in brain
chr7_+_94285637 0.13 ENST00000482108.1
ENST00000488574.1
paternally expressed 10
chrX_-_74376108 0.13 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr4_+_139936905 0.12 ENST00000280614.2
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr4_-_149365827 0.12 ENST00000344721.4
nuclear receptor subfamily 3, group C, member 2
chr3_+_101292939 0.12 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PEST proteolytic signal containing nuclear protein
chrX_+_69664706 0.12 ENST00000194900.4
ENST00000374360.3
discs, large homolog 3 (Drosophila)
chr13_+_114238997 0.11 ENST00000538138.1
ENST00000375370.5
transcription factor Dp-1
chr1_+_161284047 0.11 ENST00000367975.2
ENST00000342751.4
ENST00000432287.2
ENST00000392169.2
ENST00000513009.1
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chr5_-_142783175 0.11 ENST00000231509.3
ENST00000394464.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr15_+_41523335 0.11 ENST00000334660.5
calcineurin-like EF-hand protein 1
chr2_-_240322643 0.10 ENST00000345617.3
histone deacetylase 4
chr1_+_64239657 0.10 ENST00000371080.1
ENST00000371079.1
receptor tyrosine kinase-like orphan receptor 1
chr16_-_79634595 0.10 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr1_+_78470530 0.10 ENST00000370763.5
DnaJ (Hsp40) homolog, subfamily B, member 4
chrX_+_73641286 0.10 ENST00000587091.1
solute carrier family 16, member 2 (thyroid hormone transporter)
chr14_-_21905395 0.09 ENST00000430710.3
ENST00000553283.1
chromodomain helicase DNA binding protein 8
chrX_-_129244655 0.09 ENST00000335997.7
E74-like factor 4 (ets domain transcription factor)
chr1_-_35658736 0.09 ENST00000357214.5
splicing factor proline/glutamine-rich
chr8_-_38239732 0.08 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
Wolf-Hirschhorn syndrome candidate 1-like 1
chr8_+_28351707 0.08 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
frizzled family receptor 3
chr1_-_39339777 0.08 ENST00000397572.2
MYC binding protein
chr14_-_99737565 0.08 ENST00000357195.3
B-cell CLL/lymphoma 11B (zinc finger protein)
chr1_+_203274639 0.07 ENST00000290551.4
BTG family, member 2
chr9_-_127905736 0.07 ENST00000336505.6
ENST00000373549.4
suppressor of cancer cell invasion
chr1_+_145611010 0.07 ENST00000369291.5
ring finger protein 115
chr2_+_155554797 0.06 ENST00000295101.2
potassium inwardly-rectifying channel, subfamily J, member 3
chr5_-_168006591 0.06 ENST00000239231.6
pantothenate kinase 3
chr10_+_101419187 0.06 ENST00000370489.4
ectonucleoside triphosphate diphosphohydrolase 7
chr12_-_67072714 0.06 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
glutamate receptor interacting protein 1
chr9_+_128024067 0.06 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
GTPase activating protein and VPS9 domains 1
chr8_+_21946681 0.05 ENST00000289921.7
family with sequence similarity 160, member B2
chr10_-_120101804 0.05 ENST00000369183.4
ENST00000369172.4
family with sequence similarity 204, member A
chr4_+_41992489 0.05 ENST00000264451.7
solute carrier family 30 (zinc transporter), member 9
chr22_+_37309662 0.05 ENST00000403662.3
ENST00000262825.5
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr3_-_48632593 0.05 ENST00000454817.1
ENST00000328333.8
collagen, type VII, alpha 1
chr12_-_89918522 0.05 ENST00000529983.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr6_+_34857019 0.05 ENST00000360359.3
ENST00000535627.1
ankyrin repeat and sterile alpha motif domain containing 1A
chr3_+_38495333 0.04 ENST00000352511.4
activin A receptor, type IIB
chr3_+_43328004 0.03 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNF related kinase
chr16_-_67840442 0.03 ENST00000536251.1
ENST00000448631.2
ENST00000602677.1
ENST00000411657.2
ENST00000425512.2
ENST00000317506.3
RAN binding protein 10
chr7_+_4721885 0.02 ENST00000328914.4
forkhead box K1
chr20_+_60697480 0.02 ENST00000370915.1
ENST00000253001.4
ENST00000400318.2
ENST00000279068.6
ENST00000279069.7
LSM14B, SCD6 homolog B (S. cerevisiae)
chr2_+_134877740 0.02 ENST00000409645.1
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr18_+_43753974 0.01 ENST00000282059.6
ENST00000321319.6
chromosome 18 open reading frame 25

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUGCCC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1904933 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.3 0.9 GO:2000685 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.3 1.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.7 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 0.7 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.2 0.7 GO:0050923 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2 0.8 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.2 0.8 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.5 GO:0060061 Spemann organizer formation(GO:0060061)
0.2 0.8 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.8 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 0.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0009956 radial pattern formation(GO:0009956)
0.1 1.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.1 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 0.3 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:0048880 sensory system development(GO:0048880)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 1.6 GO:2000505 regulation of energy homeostasis(GO:2000505) regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.5 GO:0071372 response to light intensity(GO:0009642) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.8 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.9 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.3 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.2 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 1.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0099624 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) peptidyl-lysine deacetylation(GO:0034983) cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031588 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0035501 MH1 domain binding(GO:0035501)
0.3 0.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.6 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 1.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.9 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.1 1.4 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.3 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction