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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for AGCACCA
Z-value: 0.48
Motif logo
miRNA associated with seed AGCACCA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-29a-3p
|
MIMAT0000086 |
|
hsa-miR-29b-3p
|
MIMAT0000100 |
|
hsa-miR-29c-3p
|
MIMAT0000681 |
Activity profile of AGCACCA motif
Sorted Z-values of AGCACCA motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_94023873 | 39.45 |
ENST00000297268.6
|
COL1A2
|
collagen, type I, alpha 2 |
| chr2_+_189839046 | 31.77 |
ENST00000304636.3
ENST00000317840.5 |
COL3A1
|
collagen, type III, alpha 1 |
| chr1_-_204380919 | 28.81 |
ENST00000367188.4
|
PPP1R15B
|
protein phosphatase 1, regulatory subunit 15B |
| chr2_-_238323007 | 27.71 |
ENST00000295550.4
|
COL6A3
|
collagen, type VI, alpha 3 |
| chr15_-_48937982 | 23.05 |
ENST00000316623.5
|
FBN1
|
fibrillin 1 |
| chr3_-_120170052 | 22.24 |
ENST00000295633.3
|
FSTL1
|
follistatin-like 1 |
| chr1_-_35325400 | 20.52 |
ENST00000521580.2
|
SMIM12
|
small integral membrane protein 12 |
| chr16_-_46865047 | 20.28 |
ENST00000394806.2
|
C16orf87
|
chromosome 16 open reading frame 87 |
| chr16_+_55512742 | 19.67 |
ENST00000568715.1
ENST00000219070.4 |
MMP2
|
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| chr1_+_151043070 | 18.81 |
ENST00000368918.3
ENST00000368917.1 |
GABPB2
|
GA binding protein transcription factor, beta subunit 2 |
| chr5_-_149535421 | 18.26 |
ENST00000261799.4
|
PDGFRB
|
platelet-derived growth factor receptor, beta polypeptide |
| chr9_+_137533615 | 16.77 |
ENST00000371817.3
|
COL5A1
|
collagen, type V, alpha 1 |
| chr1_+_24882560 | 16.49 |
ENST00000374392.2
|
NCMAP
|
noncompact myelin associated protein |
| chr17_-_48278983 | 15.00 |
ENST00000225964.5
|
COL1A1
|
collagen, type I, alpha 1 |
| chr2_-_1748214 | 14.00 |
ENST00000433670.1
ENST00000425171.1 ENST00000252804.4 |
PXDN
|
peroxidasin homolog (Drosophila) |
| chr16_+_66914264 | 13.87 |
ENST00000311765.2
ENST00000568869.1 ENST00000561704.1 ENST00000568398.1 ENST00000566776.1 |
PDP2
|
pyruvate dehyrogenase phosphatase catalytic subunit 2 |
| chr6_+_142468361 | 13.73 |
ENST00000367630.4
|
VTA1
|
vesicle (multivesicular body) trafficking 1 |
| chr13_+_110959598 | 13.45 |
ENST00000360467.5
|
COL4A2
|
collagen, type IV, alpha 2 |
| chr11_-_18656028 | 12.98 |
ENST00000336349.5
|
SPTY2D1
|
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) |
| chr14_-_45431091 | 12.84 |
ENST00000579157.1
ENST00000396128.4 ENST00000556500.1 |
KLHL28
|
kelch-like family member 28 |
| chr3_-_57678772 | 12.54 |
ENST00000311128.5
|
DENND6A
|
DENN/MADD domain containing 6A |
| chr8_+_19796381 | 11.63 |
ENST00000524029.1
ENST00000522701.1 ENST00000311322.8 |
LPL
|
lipoprotein lipase |
| chr2_-_190044480 | 11.38 |
ENST00000374866.3
|
COL5A2
|
collagen, type V, alpha 2 |
| chr9_+_101705893 | 11.17 |
ENST00000375001.3
|
COL15A1
|
collagen, type XV, alpha 1 |
| chr4_+_40058411 | 11.00 |
ENST00000261435.6
ENST00000515550.1 |
N4BP2
|
NEDD4 binding protein 2 |
| chr8_+_42752053 | 10.93 |
ENST00000307602.4
|
HOOK3
|
hook microtubule-tethering protein 3 |
| chr17_-_15165854 | 10.64 |
ENST00000395936.1
ENST00000395938.2 |
PMP22
|
peripheral myelin protein 22 |
| chr8_+_80523321 | 10.44 |
ENST00000518111.1
|
STMN2
|
stathmin-like 2 |
| chr3_-_179169330 | 10.41 |
ENST00000232564.3
|
GNB4
|
guanine nucleotide binding protein (G protein), beta polypeptide 4 |
| chr8_+_11141925 | 10.39 |
ENST00000221086.3
|
MTMR9
|
myotubularin related protein 9 |
| chr17_-_1532106 | 10.37 |
ENST00000301335.5
ENST00000382147.4 |
SLC43A2
|
solute carrier family 43 (amino acid system L transporter), member 2 |
| chr14_+_74111578 | 10.36 |
ENST00000554113.1
ENST00000555631.2 ENST00000553645.2 ENST00000311089.3 ENST00000555919.3 ENST00000554339.1 ENST00000554871.1 |
DNAL1
|
dynein, axonemal, light chain 1 |
| chr22_+_40390930 | 10.23 |
ENST00000333407.6
|
FAM83F
|
family with sequence similarity 83, member F |
| chr12_+_54332535 | 10.06 |
ENST00000243056.3
|
HOXC13
|
homeobox C13 |
| chr2_-_220110187 | 9.78 |
ENST00000295759.7
ENST00000392089.2 |
GLB1L
|
galactosidase, beta 1-like |
| chr8_-_33424636 | 9.78 |
ENST00000256257.1
|
RNF122
|
ring finger protein 122 |
| chr5_-_79287060 | 9.61 |
ENST00000512560.1
ENST00000509852.1 ENST00000512528.1 |
MTX3
|
metaxin 3 |
| chr3_-_194991876 | 9.50 |
ENST00000310380.6
|
XXYLT1
|
xyloside xylosyltransferase 1 |
| chrX_-_51239425 | 9.50 |
ENST00000375992.3
|
NUDT11
|
nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| chr15_-_23932437 | 9.45 |
ENST00000331837.4
|
NDN
|
necdin, melanoma antigen (MAGE) family member |
| chr5_-_121413974 | 9.44 |
ENST00000231004.4
|
LOX
|
lysyl oxidase |
| chrX_-_50557014 | 9.41 |
ENST00000376020.2
|
SHROOM4
|
shroom family member 4 |
| chr5_+_157170703 | 9.39 |
ENST00000286307.5
|
LSM11
|
LSM11, U7 small nuclear RNA associated |
| chr13_-_110959478 | 9.26 |
ENST00000543140.1
ENST00000375820.4 |
COL4A1
|
collagen, type IV, alpha 1 |
| chr19_+_19431490 | 9.21 |
ENST00000392313.6
ENST00000262815.8 ENST00000609122.1 |
MAU2
|
MAU2 sister chromatid cohesion factor |
| chr17_-_8055747 | 9.02 |
ENST00000317276.4
ENST00000581703.1 |
PER1
|
period circadian clock 1 |
| chr16_-_70719925 | 8.94 |
ENST00000338779.6
|
MTSS1L
|
metastasis suppressor 1-like |
| chr2_-_37193606 | 8.65 |
ENST00000379213.2
ENST00000263918.4 |
STRN
|
striatin, calmodulin binding protein |
| chr1_-_236228403 | 8.46 |
ENST00000366595.3
|
NID1
|
nidogen 1 |
| chr11_-_59383617 | 8.35 |
ENST00000263847.1
|
OSBP
|
oxysterol binding protein |
| chr3_-_149470229 | 8.33 |
ENST00000473414.1
|
COMMD2
|
COMM domain containing 2 |
| chr19_-_10121144 | 8.10 |
ENST00000264828.3
|
COL5A3
|
collagen, type V, alpha 3 |
| chr15_+_51200859 | 8.10 |
ENST00000261842.5
|
AP4E1
|
adaptor-related protein complex 4, epsilon 1 subunit |
| chr11_+_75273101 | 8.06 |
ENST00000533603.1
ENST00000358171.3 ENST00000526242.1 |
SERPINH1
|
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| chr2_+_70142189 | 7.98 |
ENST00000264444.2
|
MXD1
|
MAX dimerization protein 1 |
| chr15_+_78730531 | 7.89 |
ENST00000258886.8
|
IREB2
|
iron-responsive element binding protein 2 |
| chr5_-_146833485 | 7.72 |
ENST00000398514.3
|
DPYSL3
|
dihydropyrimidinase-like 3 |
| chr17_-_40575535 | 7.68 |
ENST00000357037.5
|
PTRF
|
polymerase I and transcript release factor |
| chr1_+_55464600 | 7.61 |
ENST00000371265.4
|
BSND
|
Bartter syndrome, infantile, with sensorineural deafness (Barttin) |
| chr19_+_48216600 | 7.49 |
ENST00000263277.3
ENST00000538399.1 |
EHD2
|
EH-domain containing 2 |
| chr1_+_236849754 | 7.40 |
ENST00000542672.1
ENST00000366578.4 |
ACTN2
|
actinin, alpha 2 |
| chr1_-_16678914 | 7.33 |
ENST00000375592.3
|
FBXO42
|
F-box protein 42 |
| chr4_+_124320665 | 7.33 |
ENST00000394339.2
|
SPRY1
|
sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| chr1_-_115323245 | 7.30 |
ENST00000060969.5
ENST00000369528.5 |
SIKE1
|
suppressor of IKBKE 1 |
| chr2_-_201936302 | 7.29 |
ENST00000453765.1
ENST00000452799.1 ENST00000446678.1 ENST00000418596.3 |
FAM126B
|
family with sequence similarity 126, member B |
| chr1_+_151030234 | 7.24 |
ENST00000368921.3
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| chr7_+_138916231 | 7.21 |
ENST00000473989.3
ENST00000288561.8 |
UBN2
|
ubinuclein 2 |
| chr17_+_17942594 | 7.19 |
ENST00000268719.4
|
GID4
|
GID complex subunit 4 |
| chr11_-_118661828 | 6.99 |
ENST00000264018.4
|
DDX6
|
DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| chr11_-_86666427 | 6.98 |
ENST00000531380.1
|
FZD4
|
frizzled family receptor 4 |
| chr15_-_71055878 | 6.97 |
ENST00000322954.6
|
UACA
|
uveal autoantigen with coiled-coil domains and ankyrin repeats |
| chr11_-_117186946 | 6.94 |
ENST00000313005.6
ENST00000528053.1 |
BACE1
|
beta-site APP-cleaving enzyme 1 |
| chr2_+_27070964 | 6.93 |
ENST00000288699.6
|
DPYSL5
|
dihydropyrimidinase-like 5 |
| chr6_-_28220002 | 6.92 |
ENST00000377294.2
|
ZKSCAN4
|
zinc finger with KRAB and SCAN domains 4 |
| chr17_+_36508111 | 6.92 |
ENST00000331159.5
ENST00000577233.1 |
SOCS7
|
suppressor of cytokine signaling 7 |
| chrX_+_103031758 | 6.84 |
ENST00000303958.2
ENST00000361621.2 |
PLP1
|
proteolipid protein 1 |
| chr3_-_183543301 | 6.76 |
ENST00000318631.3
ENST00000431348.1 |
MAP6D1
|
MAP6 domain containing 1 |
| chr4_-_88141755 | 6.72 |
ENST00000273963.5
|
KLHL8
|
kelch-like family member 8 |
| chr19_+_46800289 | 6.71 |
ENST00000377670.4
|
HIF3A
|
hypoxia inducible factor 3, alpha subunit |
| chr7_+_43152191 | 6.63 |
ENST00000395891.2
|
HECW1
|
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| chr8_-_82024290 | 6.55 |
ENST00000220597.4
|
PAG1
|
phosphoprotein associated with glycosphingolipid microdomains 1 |
| chr12_-_48398104 | 6.50 |
ENST00000337299.6
ENST00000380518.3 |
COL2A1
|
collagen, type II, alpha 1 |
| chr5_+_112043186 | 6.42 |
ENST00000509732.1
ENST00000457016.1 ENST00000507379.1 |
APC
|
adenomatous polyposis coli |
| chr7_-_138666053 | 6.31 |
ENST00000440172.1
ENST00000422774.1 |
KIAA1549
|
KIAA1549 |
| chr14_-_77923897 | 6.24 |
ENST00000343765.2
ENST00000327028.4 ENST00000556412.1 ENST00000557466.1 ENST00000448935.2 ENST00000553888.1 ENST00000557658.1 |
VIPAS39
|
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog |
| chr15_-_86338134 | 6.15 |
ENST00000337975.5
|
KLHL25
|
kelch-like family member 25 |
| chr4_+_113066552 | 6.08 |
ENST00000309733.5
|
C4orf32
|
chromosome 4 open reading frame 32 |
| chr16_-_68482440 | 6.01 |
ENST00000219334.5
|
SMPD3
|
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) |
| chr5_-_111093406 | 6.01 |
ENST00000379671.3
|
NREP
|
neuronal regeneration related protein |
| chr10_-_120514720 | 6.01 |
ENST00000369151.3
ENST00000340214.4 |
CACUL1
|
CDK2-associated, cullin domain 1 |
| chrX_-_18372792 | 5.99 |
ENST00000251900.4
|
SCML2
|
sex comb on midleg-like 2 (Drosophila) |
| chr17_+_45810594 | 5.94 |
ENST00000177694.1
|
TBX21
|
T-box 21 |
| chr1_-_31712401 | 5.93 |
ENST00000373736.2
|
NKAIN1
|
Na+/K+ transporting ATPase interacting 1 |
| chr6_+_30524663 | 5.85 |
ENST00000376560.3
|
PRR3
|
proline rich 3 |
| chr3_-_120068143 | 5.73 |
ENST00000295628.3
|
LRRC58
|
leucine rich repeat containing 58 |
| chr15_-_79103757 | 5.72 |
ENST00000388820.4
|
ADAMTS7
|
ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| chr3_-_57199397 | 5.72 |
ENST00000296318.7
|
IL17RD
|
interleukin 17 receptor D |
| chrX_+_150345054 | 5.62 |
ENST00000218316.3
|
GPR50
|
G protein-coupled receptor 50 |
| chr12_-_101604185 | 5.62 |
ENST00000536262.2
|
SLC5A8
|
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 |
| chr3_-_48632593 | 5.57 |
ENST00000454817.1
ENST00000328333.8 |
COL7A1
|
collagen, type VII, alpha 1 |
| chr6_+_28317685 | 5.57 |
ENST00000252211.2
ENST00000341464.5 ENST00000377255.3 |
ZKSCAN3
|
zinc finger with KRAB and SCAN domains 3 |
| chr2_+_60983361 | 5.57 |
ENST00000238714.3
|
PAPOLG
|
poly(A) polymerase gamma |
| chr15_-_33360085 | 5.57 |
ENST00000334528.9
|
FMN1
|
formin 1 |
| chr20_-_39317868 | 5.53 |
ENST00000373313.2
|
MAFB
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| chr1_-_146644122 | 5.49 |
ENST00000254101.3
|
PRKAB2
|
protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| chr6_-_34113856 | 5.48 |
ENST00000538487.2
|
GRM4
|
glutamate receptor, metabotropic 4 |
| chr12_+_8185288 | 5.48 |
ENST00000162391.3
|
FOXJ2
|
forkhead box J2 |
| chr9_-_21335356 | 5.46 |
ENST00000359039.4
|
KLHL9
|
kelch-like family member 9 |
| chr7_+_130126012 | 5.42 |
ENST00000341441.5
|
MEST
|
mesoderm specific transcript |
| chr4_+_128886532 | 5.41 |
ENST00000444616.1
ENST00000388795.5 |
C4orf29
|
chromosome 4 open reading frame 29 |
| chr21_-_28338732 | 5.40 |
ENST00000284987.5
|
ADAMTS5
|
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| chr12_+_9067327 | 5.34 |
ENST00000433083.2
ENST00000544916.1 ENST00000544539.1 ENST00000539063.1 |
PHC1
|
polyhomeotic homolog 1 (Drosophila) |
| chr10_-_30024716 | 5.31 |
ENST00000375398.2
ENST00000375400.3 |
SVIL
|
supervillin |
| chr16_+_640055 | 5.27 |
ENST00000568586.1
ENST00000538492.1 ENST00000248139.3 |
RAB40C
|
RAB40C, member RAS oncogene family |
| chr6_-_88876058 | 5.26 |
ENST00000369501.2
|
CNR1
|
cannabinoid receptor 1 (brain) |
| chr9_-_37465396 | 5.25 |
ENST00000307750.4
|
ZBTB5
|
zinc finger and BTB domain containing 5 |
| chr11_-_66336060 | 5.23 |
ENST00000310325.5
|
CTSF
|
cathepsin F |
| chr22_-_20004330 | 5.23 |
ENST00000263207.3
|
ARVCF
|
armadillo repeat gene deleted in velocardiofacial syndrome |
| chr1_+_203444887 | 5.13 |
ENST00000343110.2
|
PRELP
|
proline/arginine-rich end leucine-rich repeat protein |
| chr4_-_153457197 | 5.04 |
ENST00000281708.4
|
FBXW7
|
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| chr9_+_131843377 | 5.03 |
ENST00000372546.4
ENST00000406974.3 ENST00000540102.1 |
DOLPP1
|
dolichyldiphosphatase 1 |
| chr13_+_58206655 | 4.94 |
ENST00000377918.3
|
PCDH17
|
protocadherin 17 |
| chrX_+_9754461 | 4.94 |
ENST00000380913.3
|
SHROOM2
|
shroom family member 2 |
| chr8_+_26435359 | 4.87 |
ENST00000311151.5
|
DPYSL2
|
dihydropyrimidinase-like 2 |
| chr10_-_50747064 | 4.86 |
ENST00000355832.5
ENST00000603152.1 ENST00000447839.2 |
ERCC6
PGBD3
ERCC6-PGBD3
|
excision repair cross-complementing rodent repair deficiency, complementation group 6 piggyBac transposable element derived 3 ERCC6-PGBD3 readthrough |
| chr1_+_22778337 | 4.85 |
ENST00000404138.1
ENST00000400239.2 ENST00000375647.4 ENST00000374651.4 |
ZBTB40
|
zinc finger and BTB domain containing 40 |
| chr12_-_69326940 | 4.83 |
ENST00000549781.1
ENST00000548262.1 ENST00000551568.1 ENST00000548954.1 |
CPM
|
carboxypeptidase M |
| chr14_-_80677970 | 4.81 |
ENST00000438257.4
|
DIO2
|
deiodinase, iodothyronine, type II |
| chr10_+_120789223 | 4.81 |
ENST00000425699.1
|
NANOS1
|
nanos homolog 1 (Drosophila) |
| chr6_-_80657292 | 4.76 |
ENST00000369816.4
|
ELOVL4
|
ELOVL fatty acid elongase 4 |
| chr3_-_133614597 | 4.75 |
ENST00000285208.4
ENST00000460865.3 |
RAB6B
|
RAB6B, member RAS oncogene family |
| chr2_-_206950781 | 4.72 |
ENST00000403263.1
|
INO80D
|
INO80 complex subunit D |
| chr5_+_153418466 | 4.69 |
ENST00000522782.1
ENST00000439768.2 ENST00000436816.1 ENST00000322602.5 ENST00000522177.1 ENST00000520899.1 |
MFAP3
|
microfibrillar-associated protein 3 |
| chr2_+_211342432 | 4.65 |
ENST00000430249.2
|
CPS1
|
carbamoyl-phosphate synthase 1, mitochondrial |
| chr14_+_103851712 | 4.64 |
ENST00000440884.3
ENST00000416682.2 ENST00000429436.2 ENST00000303622.9 |
MARK3
|
MAP/microtubule affinity-regulating kinase 3 |
| chr1_-_113498943 | 4.61 |
ENST00000369626.3
|
SLC16A1
|
solute carrier family 16 (monocarboxylate transporter), member 1 |
| chr10_-_735553 | 4.61 |
ENST00000280886.6
ENST00000423550.1 |
DIP2C
|
DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| chr5_-_132299313 | 4.59 |
ENST00000265343.5
|
AFF4
|
AF4/FMR2 family, member 4 |
| chr3_-_142166904 | 4.58 |
ENST00000264951.4
|
XRN1
|
5'-3' exoribonuclease 1 |
| chr10_+_104678032 | 4.55 |
ENST00000369878.4
ENST00000369875.3 |
CNNM2
|
cyclin M2 |
| chr1_+_53068020 | 4.51 |
ENST00000361314.4
|
GPX7
|
glutathione peroxidase 7 |
| chr19_+_4007644 | 4.51 |
ENST00000262971.2
|
PIAS4
|
protein inhibitor of activated STAT, 4 |
| chr12_+_32655048 | 4.43 |
ENST00000427716.2
ENST00000266482.3 |
FGD4
|
FYVE, RhoGEF and PH domain containing 4 |
| chr17_-_26941179 | 4.41 |
ENST00000301037.5
ENST00000530121.1 ENST00000525510.1 ENST00000577790.1 ENST00000531839.1 ENST00000534850.1 |
SGK494
RP11-192H23.4
|
uncharacterized serine/threonine-protein kinase SgK494 Uncharacterized protein |
| chr15_-_35047166 | 4.41 |
ENST00000290374.4
|
GJD2
|
gap junction protein, delta 2, 36kDa |
| chr5_-_178772424 | 4.38 |
ENST00000251582.7
ENST00000274609.5 |
ADAMTS2
|
ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
| chr3_-_114790179 | 4.35 |
ENST00000462705.1
|
ZBTB20
|
zinc finger and BTB domain containing 20 |
| chr8_-_23261589 | 4.32 |
ENST00000524168.1
ENST00000523833.2 ENST00000519243.1 ENST00000389131.3 |
LOXL2
|
lysyl oxidase-like 2 |
| chr15_+_99791567 | 4.30 |
ENST00000558879.1
ENST00000301981.3 ENST00000422500.2 ENST00000447360.2 ENST00000442993.2 |
LRRC28
|
leucine rich repeat containing 28 |
| chr5_+_176560742 | 4.27 |
ENST00000439151.2
|
NSD1
|
nuclear receptor binding SET domain protein 1 |
| chr7_+_73442102 | 4.26 |
ENST00000445912.1
ENST00000252034.7 |
ELN
|
elastin |
| chr10_-_128077024 | 4.24 |
ENST00000368679.4
ENST00000368676.4 ENST00000448723.1 |
ADAM12
|
ADAM metallopeptidase domain 12 |
| chr10_+_101419187 | 4.23 |
ENST00000370489.4
|
ENTPD7
|
ectonucleoside triphosphate diphosphohydrolase 7 |
| chr6_-_91006461 | 4.23 |
ENST00000257749.4
ENST00000343122.3 ENST00000406998.2 ENST00000453877.1 |
BACH2
|
BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| chr10_-_11653753 | 4.19 |
ENST00000609104.1
|
USP6NL
|
USP6 N-terminal like |
| chr14_+_69865401 | 4.18 |
ENST00000556605.1
ENST00000336643.5 ENST00000031146.4 |
SLC39A9
|
solute carrier family 39, member 9 |
| chr19_+_34745442 | 4.15 |
ENST00000299505.6
ENST00000588470.1 ENST00000589583.1 ENST00000588338.2 |
KIAA0355
|
KIAA0355 |
| chrX_+_107683096 | 4.07 |
ENST00000328300.6
ENST00000361603.2 |
COL4A5
|
collagen, type IV, alpha 5 |
| chr16_+_68298405 | 4.05 |
ENST00000219343.6
ENST00000566834.1 ENST00000566454.1 |
SLC7A6
|
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 |
| chr7_-_5553369 | 4.02 |
ENST00000453700.3
ENST00000382368.3 |
FBXL18
|
F-box and leucine-rich repeat protein 18 |
| chr14_-_51562745 | 4.02 |
ENST00000298355.3
|
TRIM9
|
tripartite motif containing 9 |
| chr14_+_64932210 | 3.99 |
ENST00000394718.4
|
AKAP5
|
A kinase (PRKA) anchor protein 5 |
| chr15_+_42066632 | 3.96 |
ENST00000457542.2
ENST00000221214.6 ENST00000260357.7 ENST00000456763.2 |
MAPKBP1
|
mitogen-activated protein kinase binding protein 1 |
| chr9_+_129567282 | 3.95 |
ENST00000449886.1
ENST00000373464.4 ENST00000450858.1 |
ZBTB43
|
zinc finger and BTB domain containing 43 |
| chr2_-_25475120 | 3.95 |
ENST00000380746.4
ENST00000402667.1 |
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha |
| chr10_+_102222798 | 3.93 |
ENST00000343737.5
|
WNT8B
|
wingless-type MMTV integration site family, member 8B |
| chr13_+_42622781 | 3.83 |
ENST00000337343.4
ENST00000261491.5 ENST00000379274.2 |
DGKH
|
diacylglycerol kinase, eta |
| chr10_-_75634260 | 3.80 |
ENST00000372765.1
ENST00000351293.3 |
CAMK2G
|
calcium/calmodulin-dependent protein kinase II gamma |
| chr1_+_182992545 | 3.79 |
ENST00000258341.4
|
LAMC1
|
laminin, gamma 1 (formerly LAMB2) |
| chr10_+_105036909 | 3.78 |
ENST00000369849.4
|
INA
|
internexin neuronal intermediate filament protein, alpha |
| chr18_-_268019 | 3.77 |
ENST00000261600.6
|
THOC1
|
THO complex 1 |
| chr8_-_120651020 | 3.76 |
ENST00000522826.1
ENST00000520066.1 ENST00000259486.6 ENST00000075322.6 |
ENPP2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| chr1_-_115212696 | 3.74 |
ENST00000393276.3
ENST00000393277.1 |
DENND2C
|
DENN/MADD domain containing 2C |
| chr2_+_110371905 | 3.71 |
ENST00000356454.3
|
SOWAHC
|
sosondowah ankyrin repeat domain family member C |
| chr5_+_140306478 | 3.70 |
ENST00000253807.2
|
PCDHAC1
|
protocadherin alpha subfamily C, 1 |
| chr10_+_18041218 | 3.70 |
ENST00000480516.1
ENST00000457860.1 |
TMEM236
|
TMEM236 |
| chr8_-_93115445 | 3.69 |
ENST00000523629.1
|
RUNX1T1
|
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| chr1_-_150849208 | 3.69 |
ENST00000358595.5
|
ARNT
|
aryl hydrocarbon receptor nuclear translocator |
| chr15_+_81071684 | 3.67 |
ENST00000220244.3
ENST00000394685.3 ENST00000356249.5 |
KIAA1199
|
KIAA1199 |
| chrX_+_119495934 | 3.65 |
ENST00000218008.3
ENST00000361319.3 ENST00000539306.1 |
ATP1B4
|
ATPase, Na+/K+ transporting, beta 4 polypeptide |
| chr19_+_709101 | 3.63 |
ENST00000338448.5
|
PALM
|
paralemmin |
| chr9_+_112403088 | 3.60 |
ENST00000448454.2
|
PALM2
|
paralemmin 2 |
| chr12_-_133464151 | 3.60 |
ENST00000315585.7
ENST00000266880.7 ENST00000443047.2 ENST00000432561.2 ENST00000450056.2 |
CHFR
|
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase |
| chr13_-_33002151 | 3.59 |
ENST00000495479.1
ENST00000343281.4 ENST00000464470.1 ENST00000380139.4 ENST00000380133.2 |
N4BP2L1
|
NEDD4 binding protein 2-like 1 |
| chr1_+_203595903 | 3.56 |
ENST00000367218.3
ENST00000367219.3 ENST00000391954.2 |
ATP2B4
|
ATPase, Ca++ transporting, plasma membrane 4 |
| chr1_-_38019878 | 3.54 |
ENST00000296215.6
|
SNIP1
|
Smad nuclear interacting protein 1 |
| chr17_+_80416482 | 3.53 |
ENST00000309794.11
ENST00000345415.7 ENST00000457415.3 ENST00000584411.1 ENST00000412079.2 ENST00000577432.1 |
NARF
|
nuclear prelamin A recognition factor |
| chr6_-_30043539 | 3.52 |
ENST00000376751.3
ENST00000244360.6 |
RNF39
|
ring finger protein 39 |
| chr5_-_176981417 | 3.52 |
ENST00000514747.1
ENST00000443375.2 ENST00000329540.5 |
FAM193B
|
family with sequence similarity 193, member B |
| chr15_+_79724858 | 3.51 |
ENST00000305428.3
|
KIAA1024
|
KIAA1024 |
| chr2_+_16080659 | 3.50 |
ENST00000281043.3
|
MYCN
|
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| chr12_-_102874416 | 3.48 |
ENST00000392904.1
ENST00000337514.6 |
IGF1
|
insulin-like growth factor 1 (somatomedin C) |
| chr11_-_119599794 | 3.46 |
ENST00000264025.3
|
PVRL1
|
poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| chr10_+_75757863 | 3.39 |
ENST00000372755.3
ENST00000211998.4 ENST00000417648.2 |
VCL
|
vinculin |
| chr1_-_72748417 | 3.38 |
ENST00000357731.5
|
NEGR1
|
neuronal growth regulator 1 |
| chrX_-_112084043 | 3.37 |
ENST00000304758.1
|
AMOT
|
angiomotin |
| chr12_+_69864129 | 3.36 |
ENST00000547219.1
ENST00000299293.2 ENST00000549921.1 ENST00000550316.1 ENST00000548154.1 ENST00000547414.1 ENST00000550389.1 ENST00000550937.1 ENST00000549092.1 ENST00000550169.1 |
FRS2
|
fibroblast growth factor receptor substrate 2 |
| chr8_+_75736761 | 3.35 |
ENST00000260113.2
|
PI15
|
peptidase inhibitor 15 |
| chr18_+_13218769 | 3.34 |
ENST00000399848.3
ENST00000361205.4 |
LDLRAD4
|
low density lipoprotein receptor class A domain containing 4 |
| chr1_+_32666188 | 3.34 |
ENST00000421922.2
|
CCDC28B
|
coiled-coil domain containing 28B |
Network of associatons between targets according to the STRING database.
First level regulatory network of AGCACCA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.0 | 28.2 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 6.9 | 34.7 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 6.1 | 18.3 | GO:0060437 | lung growth(GO:0060437) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
| 5.5 | 16.5 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 4.6 | 23.1 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) |
| 4.1 | 16.2 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 4.0 | 31.8 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 3.4 | 3.4 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
| 3.3 | 29.9 | GO:1903898 | negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
| 2.8 | 39.5 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 2.7 | 10.9 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 2.6 | 10.4 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 2.4 | 7.3 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 2.3 | 7.0 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 2.2 | 6.6 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 2.1 | 14.9 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 1.9 | 9.5 | GO:1901907 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 1.9 | 9.4 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 1.9 | 5.6 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 1.8 | 5.5 | GO:0035283 | rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 1.8 | 5.3 | GO:0099553 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
| 1.7 | 11.6 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 1.7 | 18.2 | GO:0038065 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065) |
| 1.5 | 9.0 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 1.5 | 2.9 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 1.4 | 13.0 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 1.3 | 46.7 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 1.3 | 12.5 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 1.2 | 3.6 | GO:0098736 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 1.2 | 4.6 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 1.1 | 11.1 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 1.1 | 6.6 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 1.1 | 3.3 | GO:0061743 | motor learning(GO:0061743) |
| 1.1 | 3.2 | GO:0098937 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 1.1 | 13.7 | GO:1904903 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 1.0 | 9.2 | GO:0034088 | maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) |
| 1.0 | 3.0 | GO:0071812 | circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 1.0 | 7.0 | GO:0038061 | NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 1.0 | 4.0 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 1.0 | 6.8 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
| 1.0 | 14.5 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.9 | 3.8 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
| 0.9 | 10.1 | GO:0043587 | tongue morphogenesis(GO:0043587) |
| 0.9 | 4.5 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.9 | 2.7 | GO:0021589 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
| 0.9 | 16.0 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.9 | 10.4 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.9 | 1.7 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
| 0.8 | 2.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.8 | 0.8 | GO:0090291 | negative regulation of osteoclast proliferation(GO:0090291) |
| 0.8 | 4.8 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.8 | 1.6 | GO:1901859 | negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) |
| 0.8 | 3.9 | GO:0048263 | determination of dorsal identity(GO:0048263) |
| 0.8 | 4.7 | GO:0034201 | response to oleic acid(GO:0034201) |
| 0.8 | 2.3 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.7 | 2.9 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 0.7 | 2.2 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.7 | 2.2 | GO:2000824 | negative regulation of androgen receptor activity(GO:2000824) |
| 0.7 | 5.0 | GO:0046465 | dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465) |
| 0.7 | 6.4 | GO:1904781 | positive regulation of protein localization to centrosome(GO:1904781) |
| 0.7 | 3.5 | GO:0001834 | trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 0.7 | 4.9 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.7 | 5.4 | GO:0007498 | mesoderm development(GO:0007498) |
| 0.7 | 44.7 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.7 | 2.7 | GO:0019086 | late viral transcription(GO:0019086) |
| 0.7 | 4.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.6 | 2.5 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.6 | 4.3 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.6 | 8.5 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.6 | 6.0 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.6 | 2.4 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.6 | 2.4 | GO:2000768 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 0.6 | 1.7 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.5 | 6.9 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) |
| 0.5 | 4.9 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.5 | 3.9 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
| 0.5 | 2.4 | GO:0042713 | sperm ejaculation(GO:0042713) |
| 0.5 | 5.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.5 | 1.9 | GO:1990936 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.5 | 4.2 | GO:2000773 | negative regulation of cellular senescence(GO:2000773) |
| 0.5 | 5.6 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 0.5 | 7.8 | GO:0044126 | regulation of growth of symbiont in host(GO:0044126) |
| 0.5 | 5.9 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.5 | 1.4 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.5 | 3.6 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 0.4 | 6.1 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.4 | 4.8 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.4 | 5.2 | GO:0002478 | antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.4 | 6.8 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.4 | 12.7 | GO:0007413 | axonal fasciculation(GO:0007413) |
| 0.4 | 1.3 | GO:0008050 | female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925) |
| 0.4 | 1.3 | GO:0021825 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923) |
| 0.4 | 14.0 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.4 | 2.4 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.4 | 7.2 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.4 | 2.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.4 | 1.9 | GO:0009233 | menaquinone metabolic process(GO:0009233) |
| 0.4 | 1.1 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.4 | 3.8 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.4 | 3.4 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
| 0.4 | 7.7 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.4 | 2.6 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.4 | 2.9 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.4 | 5.5 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.4 | 1.4 | GO:0032455 | renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) nerve growth factor processing(GO:0032455) |
| 0.4 | 0.7 | GO:0060061 | Spemann organizer formation(GO:0060061) |
| 0.3 | 1.4 | GO:0099525 | presynaptic dense core granule exocytosis(GO:0099525) |
| 0.3 | 2.7 | GO:0034128 | negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) |
| 0.3 | 3.3 | GO:0010990 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.3 | 1.0 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) |
| 0.3 | 2.3 | GO:0044331 | cell-cell adhesion mediated by cadherin(GO:0044331) |
| 0.3 | 5.3 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
| 0.3 | 4.2 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.3 | 2.6 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.3 | 0.6 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.3 | 1.2 | GO:0044789 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation of dopamine receptor signaling pathway(GO:0060161) |
| 0.3 | 12.1 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.3 | 2.1 | GO:0002371 | dendritic cell cytokine production(GO:0002371) |
| 0.3 | 1.8 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.3 | 2.4 | GO:0070235 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.3 | 2.1 | GO:1902219 | regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
| 0.3 | 3.5 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.3 | 2.5 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.3 | 5.5 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.3 | 0.5 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
| 0.3 | 1.9 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 0.3 | 2.1 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.3 | 4.2 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.3 | 2.4 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.3 | 2.6 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.3 | 3.1 | GO:0015074 | DNA integration(GO:0015074) |
| 0.3 | 1.0 | GO:0043323 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.3 | 1.5 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.3 | 3.8 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.2 | 4.2 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
| 0.2 | 0.7 | GO:0002316 | follicular B cell differentiation(GO:0002316) activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.2 | 6.3 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.2 | 1.2 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.2 | 2.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.2 | 3.8 | GO:0070831 | basement membrane assembly(GO:0070831) |
| 0.2 | 0.7 | GO:2000969 | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.2 | 2.9 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.2 | 3.1 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.2 | 1.3 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.2 | 5.1 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.2 | 4.7 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.2 | 8.9 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.2 | 0.8 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 0.2 | 5.6 | GO:0033622 | integrin activation(GO:0033622) |
| 0.2 | 1.2 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.2 | 0.4 | GO:0051541 | elastin metabolic process(GO:0051541) |
| 0.2 | 3.8 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.2 | 3.5 | GO:0045199 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.2 | 1.4 | GO:0021740 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.2 | 0.8 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.2 | 0.8 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.2 | 1.5 | GO:0060633 | negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) |
| 0.2 | 2.6 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.2 | 8.6 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.2 | 1.3 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.2 | 4.2 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.2 | 5.3 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
| 0.2 | 9.5 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.2 | 1.3 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.2 | 1.6 | GO:0015886 | heme transport(GO:0015886) |
| 0.2 | 0.3 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.2 | 1.6 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.2 | 12.0 | GO:0043297 | apical junction assembly(GO:0043297) |
| 0.2 | 0.9 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
| 0.2 | 0.6 | GO:0055072 | iron ion homeostasis(GO:0055072) |
| 0.1 | 23.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 2.2 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.1 | 1.1 | GO:2000288 | positive regulation of myoblast proliferation(GO:2000288) |
| 0.1 | 0.4 | GO:1902723 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.1 | 0.9 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 1.8 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 0.5 | GO:0003091 | renal water homeostasis(GO:0003091) |
| 0.1 | 8.2 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.1 | 6.0 | GO:0000768 | syncytium formation by plasma membrane fusion(GO:0000768) |
| 0.1 | 3.6 | GO:0015672 | monovalent inorganic cation transport(GO:0015672) |
| 0.1 | 0.7 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.1 | 4.9 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.1 | 1.6 | GO:0034380 | high-density lipoprotein particle assembly(GO:0034380) |
| 0.1 | 5.3 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 5.6 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 0.1 | 43.7 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 0.1 | 2.6 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.1 | 0.8 | GO:0051438 | regulation of ubiquitin-protein transferase activity(GO:0051438) |
| 0.1 | 2.0 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 3.8 | GO:0035136 | forelimb morphogenesis(GO:0035136) |
| 0.1 | 4.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.1 | 0.5 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.1 | 3.8 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.1 | 0.6 | GO:0035624 | receptor transactivation(GO:0035624) |
| 0.1 | 0.5 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.1 | 2.7 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.1 | 0.7 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.1 | 3.6 | GO:0046473 | phosphatidic acid metabolic process(GO:0046473) |
| 0.1 | 0.8 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
| 0.1 | 1.6 | GO:0015012 | heparan sulfate proteoglycan biosynthetic process(GO:0015012) |
| 0.1 | 1.0 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.1 | 0.7 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 2.1 | GO:0003338 | metanephros morphogenesis(GO:0003338) |
| 0.1 | 0.7 | GO:0060536 | cartilage morphogenesis(GO:0060536) |
| 0.1 | 0.8 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.1 | 0.9 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 0.5 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.1 | 0.9 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.1 | 3.0 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.1 | 0.5 | GO:0072386 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.1 | 4.8 | GO:0030282 | bone mineralization(GO:0030282) |
| 0.1 | 1.5 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.1 | 2.1 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.1 | 1.1 | GO:0021987 | cerebral cortex development(GO:0021987) |
| 0.1 | 9.8 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.1 | 4.5 | GO:0098869 | cellular oxidant detoxification(GO:0098869) |
| 0.1 | 7.3 | GO:0006661 | phosphatidylinositol biosynthetic process(GO:0006661) |
| 0.1 | 3.3 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
| 0.1 | 3.0 | GO:0031124 | mRNA 3'-end processing(GO:0031124) |
| 0.1 | 4.2 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.1 | 2.1 | GO:0048048 | embryonic eye morphogenesis(GO:0048048) |
| 0.1 | 2.7 | GO:0045824 | negative regulation of innate immune response(GO:0045824) |
| 0.1 | 4.0 | GO:0050868 | negative regulation of T cell activation(GO:0050868) |
| 0.1 | 1.5 | GO:0021522 | spinal cord motor neuron differentiation(GO:0021522) |
| 0.1 | 1.3 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.1 | 2.4 | GO:0001558 | regulation of cell growth(GO:0001558) |
| 0.1 | 1.0 | GO:0008285 | negative regulation of cell proliferation(GO:0008285) |
| 0.0 | 0.4 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.0 | 0.2 | GO:0001836 | release of cytochrome c from mitochondria(GO:0001836) |
| 0.0 | 0.3 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.0 | 3.0 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.0 | 1.2 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 2.6 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.0 | 4.4 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 2.5 | GO:0030516 | regulation of axon extension(GO:0030516) |
| 0.0 | 0.2 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.0 | 2.3 | GO:0031398 | positive regulation of protein ubiquitination(GO:0031398) |
| 0.0 | 0.7 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.0 | 4.1 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 1.8 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 1.8 | GO:0046578 | regulation of Ras protein signal transduction(GO:0046578) |
| 0.0 | 2.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.3 | GO:0002517 | T cell tolerance induction(GO:0002517) |
| 0.0 | 1.6 | GO:1903557 | positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557) |
| 0.0 | 4.6 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 0.5 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 0.5 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 1.4 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.6 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.2 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 1.2 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.0 | 0.4 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.0 | 1.5 | GO:0048477 | oogenesis(GO:0048477) |
| 0.0 | 1.8 | GO:0007270 | neuron-neuron synaptic transmission(GO:0007270) |
| 0.0 | 0.1 | GO:0038043 | interleukin-5-mediated signaling pathway(GO:0038043) |
| 0.0 | 1.5 | GO:0042552 | myelination(GO:0042552) |
| 0.0 | 1.0 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.0 | 1.4 | GO:0048010 | vascular endothelial growth factor receptor signaling pathway(GO:0048010) |
| 0.0 | 0.3 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 1.4 | GO:0006664 | glycolipid metabolic process(GO:0006664) liposaccharide metabolic process(GO:1903509) |
| 0.0 | 0.7 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.6 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 0.7 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 1.4 | GO:0060041 | retina development in camera-type eye(GO:0060041) |
| 0.0 | 3.9 | GO:0007015 | actin filament organization(GO:0007015) |
| 0.0 | 0.4 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.8 | GO:0006413 | translational initiation(GO:0006413) |
| 0.0 | 0.4 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.1 | 36.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 10.3 | 92.5 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 4.2 | 41.8 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 2.7 | 10.9 | GO:0070695 | FHF complex(GO:0070695) |
| 2.2 | 33.3 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 1.7 | 28.8 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 1.3 | 10.4 | GO:0036157 | outer dynein arm(GO:0036157) |
| 1.2 | 26.4 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 1.2 | 9.4 | GO:0005683 | U7 snRNP(GO:0005683) |
| 1.0 | 7.0 | GO:0001520 | outer dense fiber(GO:0001520) |
| 1.0 | 16.5 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.9 | 3.8 | GO:0005606 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
| 0.9 | 9.1 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.9 | 6.0 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.8 | 3.2 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.8 | 5.3 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.7 | 5.0 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.6 | 2.4 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.6 | 1.7 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.5 | 37.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.5 | 3.8 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.5 | 6.4 | GO:0016342 | catenin complex(GO:0016342) |
| 0.5 | 4.3 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.5 | 2.6 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.5 | 3.5 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.5 | 2.4 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.5 | 11.6 | GO:0042627 | chylomicron(GO:0042627) |
| 0.5 | 1.4 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.4 | 2.2 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 0.4 | 3.5 | GO:0005638 | lamin filament(GO:0005638) |
| 0.4 | 21.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.4 | 2.7 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.4 | 5.3 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.4 | 2.1 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.3 | 2.7 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 0.3 | 3.4 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.3 | 4.0 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.3 | 0.3 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.3 | 3.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.3 | 1.5 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.3 | 5.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.3 | 2.1 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.3 | 2.7 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.3 | 4.4 | GO:0005922 | connexon complex(GO:0005922) |
| 0.3 | 8.5 | GO:0005605 | basal lamina(GO:0005605) |
| 0.3 | 82.0 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.3 | 1.5 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.2 | 1.2 | GO:0033648 | host cell cytoplasm(GO:0030430) host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) host cell cytoplasm part(GO:0033655) tubulin complex(GO:0045298) |
| 0.2 | 1.3 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.2 | 3.3 | GO:0005883 | neurofilament(GO:0005883) |
| 0.2 | 31.1 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.2 | 2.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 3.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.2 | 1.1 | GO:0097443 | sorting endosome(GO:0097443) cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.2 | 8.1 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.2 | 3.0 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.2 | 0.5 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.2 | 0.5 | GO:0031251 | PAN complex(GO:0031251) |
| 0.2 | 4.2 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
| 0.2 | 4.6 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.2 | 2.3 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.2 | 14.6 | GO:0005901 | caveola(GO:0005901) |
| 0.2 | 41.1 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.2 | 0.6 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.2 | 3.0 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.1 | 7.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 1.2 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 1.6 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.1 | 4.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 0.9 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 4.6 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 1.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 15.0 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 2.4 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 0.7 | GO:1990752 | microtubule plus-end(GO:0035371) microtubule end(GO:1990752) |
| 0.1 | 9.6 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 9.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 0.8 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.1 | 1.1 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 0.5 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.1 | 1.2 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 3.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 2.0 | GO:0044291 | cell-cell contact zone(GO:0044291) |
| 0.1 | 7.7 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 2.4 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 10.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 12.6 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 1.0 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 8.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 13.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 1.9 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 5.2 | GO:0031461 | cullin-RING ubiquitin ligase complex(GO:0031461) |
| 0.0 | 2.2 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 0.7 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 2.5 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 1.8 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.7 | GO:0044455 | mitochondrial membrane part(GO:0044455) |
| 0.0 | 0.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.7 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 5.7 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.9 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 1.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.5 | GO:1990124 | apical dendrite(GO:0097440) messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 11.5 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 1.4 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 1.0 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 53.4 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 2.9 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 0.4 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 4.0 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 2.5 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 1.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 6.0 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 0.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 9.8 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.4 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 1.9 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.9 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 25.0 | GO:0016021 | integral component of membrane(GO:0016021) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.9 | 138.9 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 3.9 | 11.6 | GO:0017129 | triglyceride binding(GO:0017129) |
| 3.3 | 23.1 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 3.1 | 9.4 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 2.8 | 14.0 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 2.8 | 11.0 | GO:0051733 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 2.6 | 7.9 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 2.3 | 6.9 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 2.3 | 13.9 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 1.9 | 23.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 1.9 | 9.5 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 1.9 | 9.5 | GO:0052848 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 1.9 | 5.6 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 1.9 | 7.4 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 1.8 | 5.3 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
| 1.6 | 4.9 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 1.6 | 4.7 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 1.4 | 4.3 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 1.4 | 8.5 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 1.2 | 9.8 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 1.2 | 3.6 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 1.2 | 13.0 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 1.1 | 4.3 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 1.0 | 2.9 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 1.0 | 7.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 1.0 | 6.7 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.9 | 3.8 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.9 | 12.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.9 | 4.5 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.9 | 13.8 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.8 | 2.5 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 0.8 | 5.7 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.8 | 4.8 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.8 | 4.8 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.8 | 2.3 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
| 0.7 | 66.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.7 | 13.3 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.7 | 5.6 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.6 | 1.9 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.6 | 5.0 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.6 | 2.5 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 0.6 | 6.0 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.6 | 2.9 | GO:0047237 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) |
| 0.6 | 4.6 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.6 | 3.4 | GO:0043532 | angiostatin binding(GO:0043532) |
| 0.6 | 2.8 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.5 | 1.6 | GO:0015439 | heme-transporting ATPase activity(GO:0015439) |
| 0.5 | 2.2 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.5 | 2.7 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.5 | 2.1 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.5 | 5.7 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.5 | 10.4 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.5 | 2.6 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.5 | 2.6 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 0.5 | 4.4 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.5 | 3.7 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
| 0.4 | 1.3 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.4 | 4.0 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.4 | 2.6 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.4 | 10.9 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.4 | 8.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.4 | 9.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.4 | 2.4 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.4 | 2.4 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.4 | 5.5 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.4 | 8.6 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.4 | 41.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.4 | 4.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.4 | 1.1 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.3 | 3.8 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.3 | 39.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.3 | 3.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.3 | 1.0 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.3 | 12.1 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.3 | 2.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.3 | 4.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.3 | 2.6 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.3 | 1.2 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.3 | 4.8 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.3 | 1.2 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.3 | 3.0 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.3 | 4.4 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.3 | 1.7 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.3 | 4.0 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.3 | 8.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.3 | 1.4 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.3 | 2.2 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.3 | 2.4 | GO:0043426 | MRF binding(GO:0043426) |
| 0.3 | 1.5 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.2 | 1.0 | GO:0017089 | glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001) |
| 0.2 | 0.7 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.2 | 3.0 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.2 | 1.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 9.0 | GO:0070888 | E-box binding(GO:0070888) |
| 0.2 | 8.9 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.2 | 2.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.2 | 4.8 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.2 | 4.9 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.2 | 2.8 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.2 | 18.4 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.2 | 1.7 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.2 | 1.6 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.2 | 8.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.2 | 3.2 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.2 | 4.5 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 2.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 1.6 | GO:0015266 | protein channel activity(GO:0015266) BH3 domain binding(GO:0051434) |
| 0.1 | 3.5 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 3.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 6.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 6.5 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.1 | 0.5 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.1 | 7.3 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 3.9 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 11.4 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 1.3 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.1 | 5.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 2.5 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.1 | 4.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 2.1 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 3.0 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.1 | 1.8 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 2.7 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 1.3 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.1 | 0.8 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.1 | 14.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 1.9 | GO:0004659 | prenyltransferase activity(GO:0004659) |
| 0.1 | 0.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.9 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 0.8 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 1.6 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.1 | 1.4 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.1 | 10.8 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 2.9 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.1 | 0.6 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 2.2 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 3.3 | GO:0030414 | peptidase inhibitor activity(GO:0030414) |
| 0.1 | 10.1 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.1 | 0.8 | GO:0051378 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.1 | 0.3 | GO:0050072 | m7G(5')pppN diphosphatase activity(GO:0050072) |
| 0.1 | 0.5 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 4.0 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.1 | 0.7 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 1.2 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 48.1 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.1 | 2.3 | GO:0008200 | ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248) |
| 0.1 | 2.0 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.1 | 0.7 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 2.4 | GO:0042805 | actinin binding(GO:0042805) |
| 0.1 | 0.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 0.4 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 1.1 | GO:0036041 | long-chain fatty acid binding(GO:0036041) |
| 0.1 | 4.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 21.6 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 1.8 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.0 | 4.8 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 1.0 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.5 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.0 | 6.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 1.3 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 1.2 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 1.2 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 5.9 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.4 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 0.5 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 35.5 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 2.0 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 1.1 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.1 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
| 0.0 | 0.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.2 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.0 | 0.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.2 | GO:0098505 | single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505) sequence-specific single stranded DNA binding(GO:0098847) |
| 0.0 | 0.6 | GO:0015075 | ion transmembrane transporter activity(GO:0015075) |
| 0.0 | 0.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.7 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 0.5 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.4 | 209.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.8 | 23.1 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.6 | 26.0 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.6 | 20.1 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.6 | 31.5 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.5 | 7.2 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.4 | 6.9 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.4 | 9.0 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.4 | 12.2 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.3 | 9.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.2 | 2.6 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 10.4 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.2 | 3.6 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.2 | 49.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 10.6 | PID FGF PATHWAY | FGF signaling pathway |
| 0.2 | 32.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.2 | 2.5 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.2 | 3.2 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.1 | 2.5 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 7.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 3.2 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 5.3 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 3.1 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.1 | 1.2 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 3.3 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.1 | 5.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 3.4 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.1 | 0.6 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 2.9 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 3.8 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 5.3 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.1 | 0.7 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.1 | 4.5 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 3.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 1.1 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.1 | 1.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 1.3 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 2.7 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 1.6 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 5.2 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 1.9 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 1.1 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 1.5 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.8 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 2.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 1.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.5 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.2 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.1 | PID IL5 PATHWAY | IL5-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 223.1 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 1.4 | 5.7 | REACTOME SIGNALING BY FGFR | Genes involved in Signaling by FGFR |
| 0.9 | 16.0 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.8 | 19.7 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.7 | 9.9 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.6 | 17.2 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.6 | 9.4 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.5 | 13.0 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.5 | 4.2 | REACTOME SIGNALING BY EGFR IN CANCER | Genes involved in Signaling by EGFR in Cancer |
| 0.5 | 9.3 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.4 | 4.6 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.4 | 17.0 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.4 | 10.0 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.3 | 5.0 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.3 | 5.5 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.3 | 8.0 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.3 | 5.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.3 | 2.6 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.2 | 4.4 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.2 | 6.5 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.2 | 4.0 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.2 | 5.6 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.2 | 10.3 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.2 | 7.8 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.2 | 4.8 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.2 | 3.0 | REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA | Genes involved in Processing of Capped Intronless Pre-mRNA |
| 0.2 | 4.8 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.2 | 6.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 5.4 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.2 | 1.8 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.2 | 2.7 | REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX | Genes involved in Formation of RNA Pol II elongation complex |
| 0.2 | 3.8 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.2 | 5.1 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 4.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 4.0 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.1 | 1.5 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 6.7 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 2.3 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.1 | 13.6 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 6.8 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 2.4 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 1.8 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 2.0 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 15.4 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 2.5 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.1 | 4.9 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.1 | 5.8 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.6 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.1 | 3.4 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.1 | 1.3 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 2.2 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 2.8 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 4.6 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 1.8 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 2.9 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 2.7 | REACTOME EXTRACELLULAR MATRIX ORGANIZATION | Genes involved in Extracellular matrix organization |
| 0.1 | 3.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 4.9 | REACTOME PI3K CASCADE | Genes involved in PI3K Cascade |
| 0.1 | 1.4 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 1.2 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 0.8 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.1 | 1.1 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 2.3 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 1.4 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.8 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 3.7 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 1.7 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.6 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 1.5 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 11.5 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.0 | 7.5 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.5 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 0.6 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 0.8 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.3 | REACTOME CD28 CO STIMULATION | Genes involved in CD28 co-stimulation |
| 0.0 | 0.5 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 0.2 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 1.1 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.0 | 0.5 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 0.7 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |