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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for AGUGCUU

Z-value: 0.08

Motif logo

logo of

miRNA associated with seed AGUGCUU

NamemiRBASE accession
hsa-miR-302c-3p.2
hsa-miR-520f-3p
MIMAT0002830

Activity profile of AGUGCUU motif

Sorted Z-values of AGUGCUU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_20812690 11.53 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr2_-_183903133 7.43 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr21_-_27542972 6.50 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
APP
amyloid beta (A4) precursor protein
chr16_-_57318566 5.34 ENST00000569059.1
ENST00000219207.5
PLLP
plasmolipin
chrX_-_140271249 5.17 ENST00000370526.2
LDOC1
leucine zipper, down-regulated in cancer 1
chr13_-_30424821 4.68 ENST00000380680.4
UBL3
ubiquitin-like 3
chr9_+_130374537 4.49 ENST00000373302.3
ENST00000373299.1
STXBP1
syntaxin binding protein 1
chr9_-_111929560 4.39 ENST00000561981.2
FRRS1L
ferric-chelate reductase 1-like
chr22_-_36236265 4.23 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr12_-_16761007 4.22 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_+_70117153 3.88 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr4_-_102268628 3.83 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr4_-_53525406 3.42 ENST00000451218.2
ENST00000441222.3
USP46
ubiquitin specific peptidase 46
chr11_+_9406169 3.23 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr16_-_66785699 3.08 ENST00000258198.2
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr16_-_19533404 3.06 ENST00000353258.3
GDE1
glycerophosphodiester phosphodiesterase 1
chr11_+_92085262 2.78 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chrX_+_110339439 2.75 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr1_+_200708671 2.67 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr20_+_30865429 2.60 ENST00000375712.3
KIF3B
kinesin family member 3B
chr20_-_48099182 2.48 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr20_+_1875110 2.46 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chrX_+_16737718 2.33 ENST00000380155.3
SYAP1
synapse associated protein 1
chr10_+_92980517 2.32 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr19_-_49944806 2.30 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr11_-_132813566 2.29 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr18_+_21269404 2.22 ENST00000313654.9
LAMA3
laminin, alpha 3
chr2_+_110371905 2.21 ENST00000356454.3
SOWAHC
sosondowah ankyrin repeat domain family member C
chr1_-_230561475 2.21 ENST00000391860.1
PGBD5
piggyBac transposable element derived 5
chr20_+_56884752 2.20 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr16_+_24266874 2.16 ENST00000005284.3
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr17_-_78450398 2.15 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr2_+_11674213 2.15 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr1_-_244013384 2.12 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr7_-_124405681 2.12 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_+_244998602 2.10 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr11_-_85780086 2.07 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr2_+_203499901 2.05 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr2_-_86790593 2.03 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr6_-_56707943 2.03 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr3_-_149093499 2.02 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr1_+_93913713 1.99 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr20_-_47894569 1.92 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
ZNFX1
zinc finger, NFX1-type containing 1
chr1_+_184356188 1.91 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr20_+_8112824 1.91 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr12_-_42538657 1.80 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr2_-_11484710 1.78 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr11_+_61520075 1.77 ENST00000278836.5
MYRF
myelin regulatory factor
chr20_+_9494987 1.77 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chr11_+_69455855 1.74 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr7_-_40174201 1.72 ENST00000306984.6
MPLKIP
M-phase specific PLK1 interacting protein
chr16_+_7382745 1.70 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_-_70883708 1.70 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr9_-_86571628 1.67 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr2_+_9346892 1.66 ENST00000281419.3
ENST00000315273.4
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr8_+_42752053 1.65 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chrX_-_62974941 1.59 ENST00000374872.1
ENST00000253401.6
ENST00000374870.4
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr17_+_38333263 1.58 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr11_-_27494279 1.58 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr5_-_171433819 1.56 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr3_-_69435224 1.56 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr1_-_78148324 1.54 ENST00000370801.3
ENST00000433749.1
ZZZ3
zinc finger, ZZ-type containing 3
chr1_+_97187318 1.54 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr3_+_179065474 1.49 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr16_+_69373323 1.49 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr15_-_78526942 1.47 ENST00000258873.4
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr4_-_111119804 1.42 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr9_-_123476719 1.38 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr6_-_154831779 1.38 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr1_+_25071848 1.37 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr8_-_53626974 1.33 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr22_-_22221900 1.33 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr10_+_111967345 1.32 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr17_-_1083078 1.32 ENST00000574266.1
ENST00000302538.5
ABR
active BCR-related
chr6_+_57037089 1.31 ENST00000370693.5
BAG2
BCL2-associated athanogene 2
chr2_+_118846008 1.29 ENST00000245787.4
INSIG2
insulin induced gene 2
chr1_-_226076843 1.27 ENST00000272134.5
LEFTY1
left-right determination factor 1
chr8_-_124408652 1.27 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr3_-_55523966 1.26 ENST00000474267.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr4_+_113970772 1.26 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr10_+_91152303 1.18 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr11_+_73019282 1.18 ENST00000263674.3
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr17_+_26662730 1.17 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr8_+_64081118 1.16 ENST00000539294.1
YTHDF3
YTH domain family, member 3
chr13_+_97874574 1.16 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr17_-_5138099 1.10 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr4_-_99851766 1.09 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr11_-_110167352 1.08 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr13_-_79233314 1.06 ENST00000282003.6
RNF219
ring finger protein 219
chr7_-_44924939 1.06 ENST00000395699.2
PURB
purine-rich element binding protein B
chr4_+_6271558 1.06 ENST00000503569.1
ENST00000226760.1
WFS1
Wolfram syndrome 1 (wolframin)
chr10_-_6104253 1.04 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
IL2RA
interleukin 2 receptor, alpha
chr12_+_13197218 1.03 ENST00000197268.8
KIAA1467
KIAA1467
chr10_-_72648541 1.03 ENST00000299299.3
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chrX_+_128674213 1.01 ENST00000371113.4
ENST00000357121.5
OCRL
oculocerebrorenal syndrome of Lowe
chr3_+_126707437 1.00 ENST00000393409.2
ENST00000251772.4
PLXNA1
plexin A1
chr4_+_156588350 1.00 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr8_-_116681221 0.99 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr1_+_214776516 0.99 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr1_-_70671216 0.98 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr1_-_57045228 0.98 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr9_-_95432536 0.96 ENST00000287996.3
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr10_-_61666267 0.96 ENST00000263102.6
CCDC6
coiled-coil domain containing 6
chr1_+_7831323 0.95 ENST00000054666.6
VAMP3
vesicle-associated membrane protein 3
chr1_-_85156216 0.95 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr10_+_115614370 0.93 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr19_-_10121144 0.93 ENST00000264828.3
COL5A3
collagen, type V, alpha 3
chr13_-_26795840 0.92 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6
ring finger protein (C3H2C3 type) 6
chr10_+_95517566 0.90 ENST00000542308.1
LGI1
leucine-rich, glioma inactivated 1
chr11_-_108464321 0.89 ENST00000265843.4
EXPH5
exophilin 5
chr10_-_120514720 0.88 ENST00000369151.3
ENST00000340214.4
CACUL1
CDK2-associated, cullin domain 1
chr2_+_46926048 0.87 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr12_+_111471828 0.86 ENST00000261726.6
CUX2
cut-like homeobox 2
chr3_-_164913777 0.85 ENST00000475390.1
SLITRK3
SLIT and NTRK-like family, member 3
chr3_+_132136331 0.85 ENST00000260818.6
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr14_-_23504087 0.82 ENST00000493471.2
ENST00000460922.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr2_+_198380289 0.82 ENST00000233892.4
ENST00000409916.1
MOB4
MOB family member 4, phocein
chr2_+_173940442 0.82 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr15_+_69706585 0.82 ENST00000559279.1
ENST00000395392.2
KIF23
kinesin family member 23
chr3_-_176914238 0.81 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr16_-_85722530 0.81 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr1_+_183605200 0.79 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr6_+_87865262 0.78 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr12_-_93835665 0.78 ENST00000552442.1
ENST00000550657.1
UBE2N
ubiquitin-conjugating enzyme E2N
chr5_+_172483347 0.77 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr2_-_166651191 0.76 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr8_+_58907104 0.75 ENST00000361488.3
FAM110B
family with sequence similarity 110, member B
chr14_+_67826709 0.74 ENST00000256383.4
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr7_-_14942944 0.73 ENST00000403951.2
DGKB
diacylglycerol kinase, beta 90kDa
chr7_+_99613195 0.72 ENST00000324306.6
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr17_-_17875688 0.72 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr22_+_38302285 0.70 ENST00000215957.6
MICALL1
MICAL-like 1
chr15_-_45480153 0.68 ENST00000560471.1
ENST00000560540.1
SHF
Src homology 2 domain containing F
chr11_+_22688150 0.64 ENST00000454584.2
GAS2
growth arrest-specific 2
chrX_-_71933888 0.64 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
PHKA1
phosphorylase kinase, alpha 1 (muscle)
chr3_+_14989076 0.63 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr11_-_78052923 0.62 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr6_-_90348440 0.61 ENST00000520441.1
ENST00000520318.1
ENST00000523377.1
LYRM2
LYR motif containing 2
chr16_-_47495170 0.61 ENST00000320640.6
ENST00000544001.2
ITFG1
integrin alpha FG-GAP repeat containing 1
chr16_-_73082274 0.60 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr19_+_39138271 0.60 ENST00000252699.2
ACTN4
actinin, alpha 4
chr20_-_9819479 0.60 ENST00000378423.1
ENST00000353224.5
PAK7
p21 protein (Cdc42/Rac)-activated kinase 7
chr1_-_226129083 0.58 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr14_+_73603126 0.57 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
PSEN1
presenilin 1
chr20_-_35724388 0.56 ENST00000344359.3
ENST00000373664.3
RBL1
retinoblastoma-like 1 (p107)
chr13_-_29069232 0.55 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr20_-_41818373 0.55 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr17_+_28705921 0.54 ENST00000225719.4
CPD
carboxypeptidase D
chr6_-_89827720 0.54 ENST00000452027.2
SRSF12
serine/arginine-rich splicing factor 12
chr1_-_53793584 0.53 ENST00000354412.3
ENST00000347547.2
ENST00000306052.6
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr7_+_90225796 0.53 ENST00000380050.3
CDK14
cyclin-dependent kinase 14
chr14_+_35515598 0.53 ENST00000280987.4
FAM177A1
family with sequence similarity 177, member A1
chr2_+_198365122 0.52 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr18_-_500692 0.52 ENST00000400256.3
COLEC12
collectin sub-family member 12
chr1_-_21377447 0.52 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_-_68694390 0.52 ENST00000377957.3
FBXO48
F-box protein 48
chr6_-_16761678 0.51 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr3_+_37493610 0.50 ENST00000264741.5
ITGA9
integrin, alpha 9
chr17_+_38375574 0.50 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2
WAS/WASL interacting protein family, member 2
chr11_+_64126614 0.49 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr17_+_56270084 0.49 ENST00000225371.5
EPX
eosinophil peroxidase
chr2_+_185463093 0.49 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr1_-_182361327 0.48 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chrX_+_76709648 0.48 ENST00000439435.1
FGF16
fibroblast growth factor 16
chr4_-_153601136 0.48 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr10_+_180987 0.48 ENST00000381591.1
ZMYND11
zinc finger, MYND-type containing 11
chr2_+_7057523 0.48 ENST00000320892.6
RNF144A
ring finger protein 144A
chr2_+_178257372 0.47 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr2_+_242255275 0.46 ENST00000391971.2
SEPT2
septin 2
chr14_-_92572894 0.45 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr22_+_29469012 0.44 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr6_-_32095968 0.44 ENST00000375203.3
ENST00000375201.4
ATF6B
activating transcription factor 6 beta
chr12_+_32655048 0.44 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_-_218808771 0.44 ENST00000449814.1
ENST00000171887.4
TNS1
tensin 1
chr12_-_46766577 0.42 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr19_+_33463127 0.42 ENST00000589646.1
ENST00000588258.1
ENST00000590179.1
C19orf40
chromosome 19 open reading frame 40
chr7_+_139044621 0.41 ENST00000354926.4
C7orf55-LUC7L2
C7orf55-LUC7L2 readthrough
chr14_-_45431091 0.41 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr3_-_183735731 0.41 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr1_+_220701456 0.40 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr14_-_27066636 0.40 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
NOVA1
neuro-oncological ventral antigen 1
chr20_+_19193269 0.39 ENST00000328041.6
SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr7_-_123389104 0.38 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr5_-_32444828 0.38 ENST00000265069.8
ZFR
zinc finger RNA binding protein
chr6_+_41040678 0.38 ENST00000341376.6
ENST00000353205.5
NFYA
nuclear transcription factor Y, alpha
chr3_-_122233723 0.38 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr2_+_5832799 0.38 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr4_+_74606223 0.38 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr5_-_133968529 0.37 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chrX_+_77154935 0.37 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr1_+_89149905 0.36 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
PKN2
protein kinase N2
chr1_+_3607228 0.36 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73
tumor protein p73
chr6_-_33168391 0.36 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chrX_+_69664706 0.35 ENST00000194900.4
ENST00000374360.3
DLG3
discs, large homolog 3 (Drosophila)
chrX_+_70586082 0.35 ENST00000373790.4
ENST00000449580.1
ENST00000423759.1
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr10_+_85899196 0.34 ENST00000372134.3
GHITM
growth hormone inducible transmembrane protein
chr13_+_115047053 0.34 ENST00000375299.3
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr6_-_116381918 0.34 ENST00000606080.1
FRK
fyn-related kinase
chr12_-_76953284 0.34 ENST00000547544.1
ENST00000393249.2
OSBPL8
oxysterol binding protein-like 8
chr2_-_213403565 0.33 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGCUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0007412 axon target recognition(GO:0007412) regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.3 6.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
1.3 3.9 GO:0060018 astrocyte fate commitment(GO:0060018) retinal rod cell differentiation(GO:0060221)
1.3 3.8 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.8 0.8 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.8 7.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.8 2.3 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.7 4.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.7 4.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.6 1.9 GO:0090427 activation of meiosis(GO:0090427)
0.6 2.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.5 5.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4 1.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.4 1.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.4 5.2 GO:0060137 maternal process involved in parturition(GO:0060137)
0.4 1.3 GO:1904933 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.4 1.3 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.4 1.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.4 1.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.4 1.6 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 3.4 GO:0008343 adult feeding behavior(GO:0008343) righting reflex(GO:0060013)
0.3 1.3 GO:0030242 pexophagy(GO:0030242)
0.3 0.9 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.3 1.8 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.3 2.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 2.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.3 0.6 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.3 1.1 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.3 1.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.3 0.8 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 2.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.2 0.7 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2 1.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 2.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 2.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 2.1 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.2 0.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 1.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 0.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 1.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 2.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 4.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 1.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 1.1 GO:0042048 olfactory behavior(GO:0042048)
0.2 1.7 GO:0033327 Leydig cell differentiation(GO:0033327) response to UV-A(GO:0070141)
0.2 1.0 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.2 0.3 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.2 2.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 2.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 0.5 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.2 0.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 1.0 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.8 GO:0060613 fat pad development(GO:0060613)
0.1 1.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.5 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 5.8 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.1 1.0 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 3.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.4 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.5 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 3.1 GO:0051642 centrosome localization(GO:0051642)
0.1 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 2.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.0 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.4 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 0.4 GO:0032328 alanine transport(GO:0032328)
0.1 0.5 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 1.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.8 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 2.3 GO:0008038 neuron recognition(GO:0008038)
0.1 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.8 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.1 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.2 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 1.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 1.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.7 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.7 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.6 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.3 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 1.3 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.5 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 1.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 1.3 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.6 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:0032909 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0032880 regulation of protein localization(GO:0032880)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.9 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.6 GO:0006400 tRNA modification(GO:0006400)
0.0 7.1 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.7 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.1 GO:0043586 tongue development(GO:0043586)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 2.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.9 GO:0007032 endosome organization(GO:0007032)
0.0 1.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 2.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 1.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 3.2 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.0 0.4 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.9 2.6 GO:0005873 plus-end kinesin complex(GO:0005873)
0.7 7.2 GO:0097449 astrocyte projection(GO:0097449)
0.5 7.4 GO:0031209 SCAR complex(GO:0031209)
0.5 2.0 GO:0031673 H zone(GO:0031673)
0.4 3.8 GO:0005955 calcineurin complex(GO:0005955)
0.4 1.6 GO:0070695 FHF complex(GO:0070695)
0.3 2.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 1.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 0.9 GO:0005588 collagen type V trimer(GO:0005588)
0.3 2.3 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.3 2.2 GO:0005610 laminin-5 complex(GO:0005610)
0.3 0.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.3 1.8 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 0.8 GO:0000811 GINS complex(GO:0000811)
0.2 1.1 GO:0051286 cell tip(GO:0051286)
0.2 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 5.3 GO:0043218 compact myelin(GO:0043218)
0.2 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.2 2.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 1.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.8 GO:0071203 WASH complex(GO:0071203)
0.1 1.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 3.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.1 GO:0033391 chromatoid body(GO:0033391)
0.1 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 2.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.7 GO:1990752 microtubule end(GO:1990752)
0.1 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.5 GO:0097386 glial cell projection(GO:0097386)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.9 GO:0031143 pseudopodium(GO:0031143)
0.1 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.8 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 4.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 3.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 10.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0097227 sperm annulus(GO:0097227)
0.0 3.6 GO:0005643 nuclear pore(GO:0005643)
0.0 1.2 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.9 GO:0030424 axon(GO:0030424)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 1.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.8 GO:0043296 apical junction complex(GO:0043296)
0.0 2.0 GO:0005938 cell cortex(GO:0005938)
0.0 2.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.5 GO:0001726 ruffle(GO:0001726)
0.0 0.5 GO:0030666 endocytic vesicle membrane(GO:0030666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.8 3.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.6 6.5 GO:0051425 PTB domain binding(GO:0051425)
0.6 2.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.4 5.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 3.9 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.4 3.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4 1.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.3 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.0 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.3 1.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 1.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 2.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 4.5 GO:0043274 phospholipase binding(GO:0043274)
0.2 2.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.0 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.2 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.6 GO:0038025 reelin receptor activity(GO:0038025)
0.2 3.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 4.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.5 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 2.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 7.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 2.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0050733 RS domain binding(GO:0050733)
0.1 1.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.9 GO:0005521 lamin binding(GO:0005521)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 3.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 2.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.3 GO:0048018 receptor agonist activity(GO:0048018)
0.1 2.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 1.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 3.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 3.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.9 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 1.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.3 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0004601 peroxidase activity(GO:0004601)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 4.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 7.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 2.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 1.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 3.4 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 3.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.5 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 2.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 3.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis