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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for AHR_ARNT2
Z-value: 0.18
Motif logo
Transcription factors associated with AHR_ARNT2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
AHR
|
ENSG00000106546.8 | aryl hydrocarbon receptor |
|
ARNT2
|
ENSG00000172379.14 | aryl hydrocarbon receptor nuclear translocator 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ARNT2 | hg19_v2_chr15_+_80696666_80696700, hg19_v2_chr15_+_80733570_80733659 | 0.34 | 2.9e-07 | Click! |
| AHR | hg19_v2_chr7_+_17338239_17338262 | -0.13 | 5.7e-02 | Click! |
Activity profile of AHR_ARNT2 motif
Sorted Z-values of AHR_ARNT2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of AHR_ARNT2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.2 | 29.0 | GO:0070982 | L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982) |
| 6.0 | 6.0 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
| 6.0 | 18.0 | GO:0031630 | regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630) |
| 4.9 | 14.8 | GO:0019242 | methylglyoxal biosynthetic process(GO:0019242) |
| 4.2 | 16.9 | GO:0003172 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 3.7 | 11.2 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
| 3.5 | 10.6 | GO:0009183 | purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) |
| 2.9 | 14.7 | GO:1904207 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 2.9 | 8.7 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 2.8 | 39.0 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 2.6 | 7.8 | GO:1904897 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 2.2 | 11.2 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 2.2 | 8.8 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 2.1 | 12.7 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 2.0 | 6.0 | GO:2000854 | positive regulation of corticosterone secretion(GO:2000854) |
| 2.0 | 9.9 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 1.9 | 5.8 | GO:1903179 | regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) |
| 1.9 | 13.5 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 1.9 | 7.7 | GO:0043335 | protein unfolding(GO:0043335) |
| 1.9 | 5.6 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 1.8 | 21.3 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 1.8 | 8.8 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 1.7 | 6.9 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 1.7 | 5.1 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 1.7 | 3.4 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 1.7 | 10.1 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 1.6 | 4.9 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 1.6 | 4.8 | GO:0021718 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 1.6 | 6.5 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 1.6 | 4.7 | GO:1903697 | negative regulation of microvillus assembly(GO:1903697) |
| 1.6 | 4.7 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
| 1.6 | 4.7 | GO:2000374 | cadmium ion homeostasis(GO:0055073) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374) |
| 1.5 | 1.5 | GO:0060699 | regulation of endoribonuclease activity(GO:0060699) |
| 1.5 | 12.3 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 1.5 | 7.4 | GO:0042816 | vitamin B6 metabolic process(GO:0042816) |
| 1.5 | 10.2 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 1.4 | 1.4 | GO:0002188 | translation reinitiation(GO:0002188) |
| 1.4 | 5.6 | GO:0006528 | asparagine metabolic process(GO:0006528) |
| 1.4 | 5.5 | GO:2000343 | positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343) |
| 1.4 | 4.1 | GO:1902309 | regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 1.4 | 1.4 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 1.4 | 5.4 | GO:0001188 | RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189) |
| 1.3 | 6.7 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 1.3 | 5.3 | GO:1901895 | positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895) |
| 1.3 | 4.0 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 1.3 | 6.6 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 1.3 | 10.3 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 1.3 | 7.7 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 1.3 | 21.6 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 1.3 | 3.8 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) |
| 1.3 | 3.8 | GO:0090034 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
| 1.3 | 15.1 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
| 1.3 | 5.0 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 1.2 | 4.8 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 1.2 | 3.6 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
| 1.2 | 3.5 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 1.2 | 4.7 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 1.2 | 3.5 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 1.2 | 10.4 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 1.2 | 3.5 | GO:0070631 | spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790) |
| 1.2 | 52.1 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 1.1 | 10.2 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) |
| 1.1 | 3.4 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 1.1 | 8.8 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 1.1 | 10.7 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 1.1 | 3.2 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 1.1 | 2.1 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 1.1 | 6.3 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 1.1 | 1.1 | GO:0051885 | positive regulation of anagen(GO:0051885) |
| 1.0 | 7.3 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 1.0 | 2.1 | GO:1990523 | bone regeneration(GO:1990523) |
| 1.0 | 1.0 | GO:0008355 | olfactory learning(GO:0008355) |
| 1.0 | 1.0 | GO:0097324 | melanocyte migration(GO:0097324) |
| 1.0 | 4.0 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 1.0 | 5.0 | GO:1903056 | regulation of melanosome organization(GO:1903056) |
| 1.0 | 5.0 | GO:1902075 | cellular response to salt(GO:1902075) |
| 1.0 | 6.0 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 1.0 | 14.8 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 1.0 | 4.9 | GO:2000769 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 1.0 | 2.9 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 1.0 | 2.0 | GO:1904351 | negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166) |
| 1.0 | 5.8 | GO:0032328 | alanine transport(GO:0032328) |
| 1.0 | 2.9 | GO:0015883 | FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) |
| 1.0 | 1.0 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
| 0.9 | 4.7 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.9 | 2.8 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.9 | 2.8 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 0.9 | 8.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.9 | 3.6 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
| 0.9 | 1.8 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 0.9 | 2.6 | GO:1904530 | negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617) |
| 0.8 | 2.5 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.8 | 2.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.8 | 4.2 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.8 | 2.5 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.8 | 0.8 | GO:0021897 | forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) |
| 0.8 | 10.7 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.8 | 3.3 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.8 | 25.4 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.8 | 3.3 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.8 | 1.6 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.8 | 14.5 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.8 | 3.2 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.8 | 17.6 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 0.8 | 9.6 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.8 | 2.4 | GO:2000173 | negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173) |
| 0.8 | 2.4 | GO:0033341 | regulation of collagen binding(GO:0033341) |
| 0.8 | 4.0 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 0.8 | 6.2 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.8 | 2.3 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
| 0.8 | 2.3 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.8 | 3.0 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.8 | 2.3 | GO:2000809 | positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.8 | 5.3 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.8 | 2.3 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
| 0.8 | 5.3 | GO:0032097 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 0.7 | 5.9 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.7 | 4.4 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 0.7 | 7.2 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.7 | 0.7 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
| 0.7 | 4.2 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.7 | 2.1 | GO:0035927 | mitochondrial RNA 3'-end processing(GO:0000965) RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928) |
| 0.7 | 7.6 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.7 | 8.3 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.7 | 0.7 | GO:0009182 | purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) |
| 0.7 | 11.7 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
| 0.7 | 2.7 | GO:1903978 | regulation of microglial cell activation(GO:1903978) |
| 0.7 | 2.7 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.7 | 3.4 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.7 | 2.7 | GO:2000437 | monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) |
| 0.7 | 2.0 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.7 | 2.0 | GO:0051595 | response to methylglyoxal(GO:0051595) |
| 0.7 | 4.7 | GO:1904044 | response to aldosterone(GO:1904044) |
| 0.7 | 2.7 | GO:0019322 | pentose biosynthetic process(GO:0019322) |
| 0.7 | 2.0 | GO:0021530 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.7 | 2.0 | GO:1901624 | negative regulation of lymphocyte chemotaxis(GO:1901624) |
| 0.7 | 1.3 | GO:0008306 | associative learning(GO:0008306) |
| 0.6 | 6.5 | GO:1900038 | negative regulation of cellular response to hypoxia(GO:1900038) |
| 0.6 | 3.2 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.6 | 9.7 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.6 | 5.8 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.6 | 0.6 | GO:0090069 | regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232) |
| 0.6 | 2.5 | GO:0001757 | somite specification(GO:0001757) |
| 0.6 | 7.0 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.6 | 5.7 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.6 | 1.3 | GO:2000364 | regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366) |
| 0.6 | 2.5 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.6 | 3.1 | GO:1903748 | negative regulation of establishment of protein localization to mitochondrion(GO:1903748) |
| 0.6 | 0.6 | GO:0071500 | cellular response to nitrosative stress(GO:0071500) |
| 0.6 | 5.0 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.6 | 3.1 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 0.6 | 12.1 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.6 | 4.8 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.6 | 3.0 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.6 | 4.7 | GO:0072603 | interleukin-5 secretion(GO:0072603) regulation of interleukin-5 secretion(GO:2000662) |
| 0.6 | 1.2 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.6 | 24.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.6 | 6.4 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.6 | 2.9 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.6 | 1.7 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.6 | 3.5 | GO:0015853 | adenine transport(GO:0015853) |
| 0.6 | 2.3 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.6 | 2.3 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.6 | 5.6 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.6 | 4.4 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.6 | 13.3 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.5 | 2.7 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 0.5 | 2.2 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
| 0.5 | 1.6 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.5 | 2.2 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.5 | 2.2 | GO:0016259 | selenocysteine metabolic process(GO:0016259) |
| 0.5 | 2.7 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.5 | 1.1 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
| 0.5 | 2.1 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 0.5 | 2.1 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 0.5 | 3.2 | GO:0006561 | proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129) |
| 0.5 | 3.1 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.5 | 1.6 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.5 | 2.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.5 | 2.6 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.5 | 6.6 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.5 | 3.0 | GO:2000821 | regulation of grooming behavior(GO:2000821) |
| 0.5 | 20.1 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.5 | 3.0 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.5 | 3.5 | GO:2000503 | regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 0.5 | 2.5 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.5 | 0.5 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
| 0.5 | 1.5 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 0.5 | 3.9 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.5 | 1.5 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.5 | 1.5 | GO:1900226 | positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
| 0.5 | 2.4 | GO:1903333 | negative regulation of protein folding(GO:1903333) |
| 0.5 | 6.2 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 0.5 | 0.9 | GO:0036481 | intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 0.5 | 1.4 | GO:1901297 | arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.5 | 6.1 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
| 0.5 | 1.9 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.5 | 4.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.5 | 2.3 | GO:0048690 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 0.5 | 32.6 | GO:0070125 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 0.5 | 1.4 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.4 | 3.1 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.4 | 11.7 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.4 | 1.8 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.4 | 2.7 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.4 | 1.8 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
| 0.4 | 0.9 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.4 | 16.6 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
| 0.4 | 1.7 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.4 | 2.5 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.4 | 0.8 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.4 | 0.8 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.4 | 13.1 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.4 | 4.6 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.4 | 3.3 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.4 | 3.7 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 0.4 | 0.4 | GO:0070602 | regulation of centromeric sister chromatid cohesion(GO:0070602) |
| 0.4 | 2.8 | GO:0045007 | depurination(GO:0045007) |
| 0.4 | 6.9 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.4 | 0.8 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.4 | 2.0 | GO:0033489 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 0.4 | 21.5 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.4 | 1.2 | GO:0006788 | heme oxidation(GO:0006788) |
| 0.4 | 1.2 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.4 | 6.1 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.4 | 3.5 | GO:0002911 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
| 0.4 | 1.5 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.4 | 3.1 | GO:0014052 | regulation of gamma-aminobutyric acid secretion(GO:0014052) |
| 0.4 | 0.4 | GO:0060300 | regulation of cytokine activity(GO:0060300) |
| 0.4 | 1.1 | GO:0009407 | toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487) |
| 0.4 | 4.9 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 0.4 | 11.6 | GO:0006101 | citrate metabolic process(GO:0006101) |
| 0.4 | 6.6 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.4 | 2.2 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.4 | 1.5 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.4 | 2.9 | GO:0086036 | regulation of cardiac muscle cell membrane potential(GO:0086036) |
| 0.4 | 2.2 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.4 | 6.4 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.4 | 1.1 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 0.3 | 11.8 | GO:0042407 | cristae formation(GO:0042407) |
| 0.3 | 1.0 | GO:0097112 | gamma-aminobutyric acid receptor clustering(GO:0097112) |
| 0.3 | 0.7 | GO:1900040 | regulation of interleukin-2 secretion(GO:1900040) negative regulation of interleukin-2 secretion(GO:1900041) |
| 0.3 | 5.5 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.3 | 3.4 | GO:0008216 | spermidine metabolic process(GO:0008216) |
| 0.3 | 0.7 | GO:0036337 | Fas signaling pathway(GO:0036337) |
| 0.3 | 6.8 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.3 | 1.0 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
| 0.3 | 1.7 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.3 | 0.7 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 0.3 | 2.3 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.3 | 18.0 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.3 | 3.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.3 | 4.5 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.3 | 2.9 | GO:0006987 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) |
| 0.3 | 1.3 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.3 | 1.0 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
| 0.3 | 1.0 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 0.3 | 2.5 | GO:2000172 | regulation of branching morphogenesis of a nerve(GO:2000172) |
| 0.3 | 1.6 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.3 | 8.2 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.3 | 1.9 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.3 | 0.9 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.3 | 1.2 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.3 | 2.8 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.3 | 1.5 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 0.3 | 0.6 | GO:0099622 | membrane repolarization during cardiac muscle cell action potential(GO:0086013) cardiac muscle cell membrane repolarization(GO:0099622) atrial cardiac muscle cell membrane repolarization(GO:0099624) |
| 0.3 | 1.8 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.3 | 1.2 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 0.3 | 1.5 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.3 | 0.9 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.3 | 1.5 | GO:0071233 | cellular response to leucine(GO:0071233) |
| 0.3 | 0.9 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 0.3 | 10.5 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.3 | 0.9 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.3 | 6.2 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.3 | 1.2 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.3 | 3.8 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.3 | 1.7 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 0.3 | 0.3 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.3 | 3.1 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.3 | 6.6 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.3 | 0.3 | GO:0010813 | neuropeptide catabolic process(GO:0010813) |
| 0.3 | 0.8 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.3 | 0.6 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.3 | 6.8 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.3 | 0.8 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 0.3 | 1.4 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.3 | 1.1 | GO:0006238 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 0.3 | 0.8 | GO:2001206 | positive regulation of osteoclast development(GO:2001206) |
| 0.3 | 0.8 | GO:0006286 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) |
| 0.3 | 6.4 | GO:0035067 | negative regulation of histone acetylation(GO:0035067) |
| 0.3 | 0.8 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 0.3 | 0.8 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 0.3 | 0.5 | GO:0070256 | negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 0.3 | 0.3 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.3 | 1.8 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.3 | 4.4 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.3 | 1.8 | GO:1903859 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.3 | 1.8 | GO:1903679 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.3 | 1.0 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.3 | 4.1 | GO:0009154 | purine ribonucleotide catabolic process(GO:0009154) |
| 0.3 | 0.5 | GO:0009181 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 0.3 | 2.8 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.3 | 3.0 | GO:0061339 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.3 | 1.0 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.3 | 2.0 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.3 | 0.8 | GO:0043012 | regulation of fusion of sperm to egg plasma membrane(GO:0043012) |
| 0.2 | 1.0 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.2 | 0.5 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 0.2 | 0.7 | GO:0002097 | tRNA wobble base modification(GO:0002097) |
| 0.2 | 1.2 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.2 | 0.2 | GO:0035411 | catenin import into nucleus(GO:0035411) |
| 0.2 | 1.0 | GO:0019046 | release from viral latency(GO:0019046) gene conversion(GO:0035822) |
| 0.2 | 1.0 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.2 | 1.2 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.2 | 1.7 | GO:2000111 | positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.2 | 1.7 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.2 | 0.7 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.2 | 0.9 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 0.2 | 1.6 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.2 | 1.2 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.2 | 2.8 | GO:2000678 | negative regulation of transcription regulatory region DNA binding(GO:2000678) |
| 0.2 | 1.2 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.2 | 2.1 | GO:0018916 | nitrobenzene metabolic process(GO:0018916) |
| 0.2 | 17.7 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
| 0.2 | 1.6 | GO:0042045 | epithelial fluid transport(GO:0042045) |
| 0.2 | 3.2 | GO:1904152 | regulation of retrograde protein transport, ER to cytosol(GO:1904152) |
| 0.2 | 4.5 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.2 | 2.9 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.2 | 7.3 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.2 | 2.2 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 0.2 | 0.7 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
| 0.2 | 1.7 | GO:0090672 | RNA localization to Cajal body(GO:0090670) telomerase RNA localization to Cajal body(GO:0090671) telomerase RNA localization(GO:0090672) regulation of telomerase RNA localization to Cajal body(GO:1904872) |
| 0.2 | 5.9 | GO:0046034 | ATP metabolic process(GO:0046034) |
| 0.2 | 0.4 | GO:0046545 | female gonad development(GO:0008585) development of primary female sexual characteristics(GO:0046545) |
| 0.2 | 1.3 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.2 | 1.1 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.2 | 0.7 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.2 | 2.6 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.2 | 3.7 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.2 | 3.0 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.2 | 2.1 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.2 | 1.9 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.2 | 2.5 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.2 | 1.3 | GO:0051643 | secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643) |
| 0.2 | 1.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.2 | 7.2 | GO:0042417 | dopamine metabolic process(GO:0042417) |
| 0.2 | 0.6 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.2 | 0.4 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.2 | 4.5 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.2 | 0.8 | GO:1903278 | regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of potassium ion import(GO:1903288) |
| 0.2 | 0.6 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.2 | 0.4 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.2 | 0.6 | GO:0007379 | segment specification(GO:0007379) |
| 0.2 | 0.6 | GO:0032594 | protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596) |
| 0.2 | 0.8 | GO:0072114 | pronephros morphogenesis(GO:0072114) |
| 0.2 | 2.0 | GO:0032543 |