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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ALX3

Z-value: 0.14

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Transcription factors associated with ALX3

Gene Symbol Gene ID Gene Info
ALX3
ENSG00000156150.6 ALX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX3hg19_v2_chr1_-_110613276_1106133220.018.9e-01Click!

Activity profile of ALX3 motif

Sorted Z-values of ALX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_25865159 8.36 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_-_89160770 6.39 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr10_+_5135981 6.28 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr4_+_113568207 5.96 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr2_+_90077680 5.75 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr16_-_28634874 5.64 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr2_-_89385283 5.38 ENST00000390252.2
IGKV3-15
immunoglobulin kappa variable 3-15
chr11_-_63376013 5.34 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr4_-_103749205 5.27 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_-_103749179 4.43 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr2_+_90273679 4.42 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr15_-_20193370 4.39 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr14_-_107049312 4.33 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr16_+_12059091 4.12 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr16_-_28608364 4.02 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr3_-_141747950 4.02 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_+_90211643 3.83 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr11_-_71823796 3.81 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr1_+_28261533 3.76 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr11_-_71823715 3.73 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr11_-_71823266 3.61 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr16_+_15489603 3.61 ENST00000568766.1
ENST00000287594.7
RP11-1021N1.1
MPV17L
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr14_-_78083112 3.56 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr16_-_28621298 3.51 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_+_71900572 3.42 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr11_+_71900703 3.38 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr2_+_68961934 3.30 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr16_-_28621312 3.23 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr2_+_68961905 3.18 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr2_+_68962014 3.06 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr16_+_12059050 3.04 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_+_56435637 3.03 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr6_+_34204642 2.93 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr6_+_160542821 2.83 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr16_-_28621353 2.82 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_-_24126023 2.81 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chr2_-_220264703 2.78 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr2_-_136678123 2.67 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr2_+_187371440 2.57 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr3_+_139063372 2.53 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr17_-_64225508 2.51 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr7_-_87856280 2.47 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr6_+_160542870 2.45 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr16_-_28608424 2.36 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr5_-_98262240 2.34 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr1_-_24306835 2.31 ENST00000484146.2
SRSF10
serine/arginine-rich splicing factor 10
chr15_+_64680003 2.25 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr10_-_95242044 2.25 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr7_-_87856303 2.23 ENST00000394641.3
SRI
sorcin
chr6_-_36515177 2.20 ENST00000229812.7
STK38
serine/threonine kinase 38
chr10_-_95241951 2.11 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr16_-_55866997 2.09 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr19_+_50016411 2.09 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_50016610 2.07 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr2_-_89340242 2.02 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr17_-_7167279 2.01 ENST00000571932.2
CLDN7
claudin 7
chr14_-_106552755 1.90 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr16_+_72088376 1.88 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr19_+_36139125 1.87 ENST00000246554.3
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr1_+_220267429 1.80 ENST00000366922.1
ENST00000302637.5
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
chr5_+_115177178 1.69 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chrX_-_77225135 1.69 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr20_-_33735070 1.68 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr11_-_62323702 1.67 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr7_-_144435985 1.66 ENST00000549981.1
TPK1
thiamin pyrophosphokinase 1
chr17_+_35851570 1.64 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr9_-_115095123 1.61 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr9_+_90112741 1.58 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr1_+_28261621 1.57 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_28261492 1.53 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr15_+_58702742 1.53 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr3_-_141719195 1.53 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr20_-_43133491 1.52 ENST00000411544.1
SERINC3
serine incorporator 3
chr1_-_150738261 1.51 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr11_+_57480046 1.47 ENST00000378312.4
ENST00000278422.4
TMX2
thioredoxin-related transmembrane protein 2
chrX_+_77154935 1.46 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr9_+_90112590 1.43 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chr11_-_327537 1.43 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr9_+_90112767 1.39 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr1_-_54411255 1.36 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr12_+_104337515 1.33 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr9_+_90112117 1.32 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr1_-_54411240 1.32 ENST00000371378.2
HSPB11
heat shock protein family B (small), member 11
chr11_-_107729887 1.31 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr1_+_62439037 1.30 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr3_+_138340049 1.25 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr1_-_150669500 1.23 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr4_+_71859156 1.20 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr14_-_67878917 1.18 ENST00000216446.4
PLEK2
pleckstrin 2
chr14_-_106668095 1.17 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr14_-_54423529 1.16 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr1_+_186265399 1.16 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr3_+_121774202 1.14 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr10_-_105845674 1.14 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr3_+_186353756 1.13 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr19_+_42817527 1.10 ENST00000598766.1
TMEM145
transmembrane protein 145
chr4_-_103748880 1.03 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_-_120243545 1.01 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr14_+_39736582 0.99 ENST00000556148.1
ENST00000348007.3
CTAGE5
CTAGE family, member 5
chr12_+_7014126 0.98 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr2_+_102615416 0.97 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr12_-_10282836 0.95 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr11_+_35201826 0.93 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr8_-_91095099 0.92 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr12_+_28410128 0.92 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr12_-_122985067 0.89 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr15_+_58724184 0.88 ENST00000433326.2
LIPC
lipase, hepatic
chr2_+_217524323 0.87 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr6_-_7313381 0.87 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1
signal sequence receptor, alpha
chr3_+_138340067 0.86 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr6_-_87804815 0.86 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr16_+_31271274 0.80 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr4_-_103749313 0.77 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_+_115572415 0.77 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr12_-_86650077 0.76 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chrX_+_135618258 0.72 ENST00000440515.1
ENST00000456412.1
VGLL1
vestigial like 1 (Drosophila)
chr4_-_103749105 0.71 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_+_107738240 0.70 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr19_+_48949030 0.69 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr11_+_114168085 0.68 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr7_+_120628731 0.68 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr14_+_22977587 0.67 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr17_-_39191107 0.64 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr16_-_30122717 0.64 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr9_+_34652164 0.63 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr14_+_32798462 0.61 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr5_+_176811431 0.61 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr4_+_80584903 0.59 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr1_+_157963063 0.58 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL
kin of IRRE like (Drosophila)
chr3_-_151034734 0.55 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr2_+_166095898 0.53 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr7_-_87342564 0.51 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr12_+_7013897 0.51 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr11_+_5710919 0.50 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr19_-_36304201 0.49 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr14_+_32798547 0.49 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr4_+_37455536 0.48 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr12_-_86650045 0.47 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_+_7014064 0.47 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr10_+_70661014 0.45 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr20_-_50722183 0.45 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr17_+_1674982 0.45 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_-_92952433 0.45 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr4_+_110736659 0.45 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chr12_-_22063787 0.44 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr12_+_15699286 0.44 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr4_+_142142035 0.44 ENST00000262990.4
ENST00000512809.1
ENST00000503649.1
ENST00000512738.1
ENST00000421169.2
ZNF330
zinc finger protein 330
chr20_+_1099233 0.43 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr14_+_74034310 0.43 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr6_+_158733692 0.37 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr6_+_161123270 0.37 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr4_-_66536057 0.35 ENST00000273854.3
EPHA5
EPH receptor A5
chr2_+_234826016 0.33 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr2_+_102953608 0.30 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr9_+_105757590 0.27 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr4_-_164534657 0.27 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr19_+_49199209 0.26 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr4_-_66536196 0.26 ENST00000511294.1
EPHA5
EPH receptor A5
chr8_+_30244580 0.25 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr11_+_7618413 0.23 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_+_26183958 0.22 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chrX_+_153533275 0.19 ENST00000426989.1
ENST00000426203.1
ENST00000369912.2
TKTL1
transketolase-like 1
chr6_+_154360357 0.18 ENST00000330432.7
ENST00000360422.4
OPRM1
opioid receptor, mu 1
chr12_+_122688090 0.15 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr8_+_50824233 0.14 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr7_+_107224364 0.13 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr1_+_81771806 0.12 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr3_+_45927994 0.11 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chr6_+_26402517 0.11 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr5_+_140201183 0.09 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr1_-_24306798 0.09 ENST00000374452.5
ENST00000492112.2
ENST00000343255.5
ENST00000344989.6
SRSF10
serine/arginine-rich splicing factor 10
chr18_+_29027696 0.09 ENST00000257189.4
DSG3
desmoglein 3
chr3_+_183853052 0.09 ENST00000273783.3
ENST00000432569.1
ENST00000444495.1
EIF2B5
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
chr1_-_151431647 0.07 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr1_+_225600404 0.04 ENST00000366845.2
AC092811.1
AC092811.1
chr12_-_112123524 0.03 ENST00000327551.6
BRAP
BRCA1 associated protein
chr3_+_148709128 0.03 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
GYG1
glycogenin 1
chr21_-_15918618 0.03 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr18_-_67624160 0.02 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr6_+_26402465 0.01 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr10_+_35484793 0.00 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chrX_+_108779004 0.00 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
2.1 6.3 GO:0016095 polyprenol catabolic process(GO:0016095)
0.9 3.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.9 3.6 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.9 2.7 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.9 21.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.8 5.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.8 5.3 GO:0048241 epinephrine transport(GO:0048241)
0.7 2.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.7 6.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.7 4.7 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.6 1.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.6 1.8 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.6 4.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.6 11.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.6 1.7 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.4 1.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.4 2.5 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.4 1.7 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.4 1.2 GO:2000005 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.4 1.1 GO:0032641 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.4 6.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.4 4.4 GO:0001778 plasma membrane repair(GO:0001778)
0.3 1.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 11.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 1.0 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 1.5 GO:0009597 detection of virus(GO:0009597)
0.2 2.8 GO:0019388 galactose catabolic process(GO:0019388)
0.2 2.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.2 2.7 GO:0070986 left/right axis specification(GO:0070986)
0.2 0.6 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 2.4 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 24.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 7.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.2 3.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 5.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.4 GO:2000048 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.9 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 1.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 2.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 1.7 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.9 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.3 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.1 1.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 6.4 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.9 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.5 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 2.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:0050955 thermoception(GO:0050955)
0.1 0.4 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.2 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 2.0 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.8 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.7 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 1.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 8.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.9 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.5 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 2.3 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.0 GO:0010226 response to lithium ion(GO:0010226)
0.0 1.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 2.5 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 1.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 1.4 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.0 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.6 GO:0007566 embryo implantation(GO:0007566)
0.0 5.3 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.5 GO:0070206 protein trimerization(GO:0070206)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.7 4.7 GO:0044326 dendritic spine neck(GO:0044326)
0.5 1.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 6.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 11.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 2.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 1.5 GO:0036021 endolysosome lumen(GO:0036021)
0.2 0.8 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.2 1.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 2.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 2.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 5.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 9.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.3 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.1 1.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.4 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.7 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 2.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 8.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 6.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.7 GO:0043034 costamere(GO:0043034)
0.0 3.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.4 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 1.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 4.3 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 3.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 9.3 GO:0010008 endosome membrane(GO:0010008)
0.0 2.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 2.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 17.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 21.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.7 6.8 GO:0061714 folic acid receptor activity(GO:0061714)
1.6 6.3 GO:0047023 enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
1.3 5.3 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.2 3.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.1 5.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
1.0 4.2 GO:0019770 IgG receptor activity(GO:0019770)
0.9 2.8 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.7 6.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.6 1.8 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.5 2.7 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.5 2.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.7 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 2.1 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3 2.4 GO:0050733 RS domain binding(GO:0050733)
0.3 1.9 GO:0030492 hemoglobin binding(GO:0030492)
0.3 11.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 0.7 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.2 2.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 1.7 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 1.0 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 5.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.7 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.2 1.3 GO:0046790 virion binding(GO:0046790)
0.2 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.2 1.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 31.6 GO:0003823 antigen binding(GO:0003823)
0.1 1.2 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.5 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 1.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 2.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 2.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 4.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 1.7 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.8 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.2 GO:0004802 transketolase activity(GO:0004802)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 5.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.1 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 6.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.7 GO:0004896 cytokine receptor activity(GO:0004896)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 5.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 5.6 PID E2F PATHWAY E2F transcription factor network
0.0 2.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.2 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 21.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 5.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 5.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 5.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 12.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3 2.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 2.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 3.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 4.5 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 1.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 8.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 3.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 3.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling