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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ATF7

Z-value: 0.36

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Transcription factors associated with ATF7

Gene Symbol Gene ID Gene Info
ATF7
ENSG00000170653.14 activating transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF7hg19_v2_chr12_-_54020107_54020199,
hg19_v2_chr12_-_53994805_53994817		0.143.4e-02Click!

Activity profile of ATF7 motif

Sorted Z-values of ATF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_76829441 9.86 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr1_+_26496362 7.92 ENST00000374266.5
ENST00000270812.5
ZNF593
zinc finger protein 593
chr11_+_12695944 7.68 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr15_-_91537723 7.31 ENST00000394249.3
ENST00000559811.1
ENST00000442656.2
ENST00000557905.1
ENST00000361919.3
PRC1
protein regulator of cytokinesis 1
chr11_+_12696102 6.86 ENST00000527636.1
ENST00000527376.1
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr4_-_122744998 6.09 ENST00000274026.5
CCNA2
cyclin A2
chr19_+_10362577 6.08 ENST00000592514.1
ENST00000307422.5
ENST00000253099.6
ENST00000590150.1
ENST00000590669.1
MRPL4
mitochondrial ribosomal protein L4
chr22_-_44258360 5.91 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chr6_-_3157760 5.82 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr16_+_81040794 5.67 ENST00000439957.3
ENST00000393335.3
ENST00000428963.2
ENST00000564669.1
CENPN
centromere protein N
chr19_+_10362882 5.27 ENST00000393733.2
ENST00000588502.1
MRPL4
mitochondrial ribosomal protein L4
chr16_-_3767506 5.26 ENST00000538171.1
TRAP1
TNF receptor-associated protein 1
chr16_-_3767551 5.24 ENST00000246957.5
TRAP1
TNF receptor-associated protein 1
chr8_+_98788003 5.22 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr4_-_104119528 4.92 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr17_+_7155556 4.87 ENST00000570500.1
ENST00000574993.1
ENST00000396628.2
ENST00000573657.1
ELP5
elongator acetyltransferase complex subunit 5
chr14_+_68086515 4.84 ENST00000261783.3
ARG2
arginase 2
chr16_+_2039946 4.63 ENST00000248121.2
ENST00000568896.1
SYNGR3
synaptogyrin 3
chr16_+_3068393 4.52 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr7_+_5632436 4.40 ENST00000340250.6
ENST00000382361.3
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr7_+_56019486 4.21 ENST00000446692.1
ENST00000285298.4
ENST00000443449.1
GBAS
MRPS17
glioblastoma amplified sequence
mitochondrial ribosomal protein S17
chr1_+_156030937 4.17 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr2_-_97760576 4.17 ENST00000414820.1
ENST00000272610.3
FAHD2B
fumarylacetoacetate hydrolase domain containing 2B
chr11_+_18343800 4.14 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr14_+_93389425 4.11 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr22_+_32340481 4.05 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr11_+_4116005 3.97 ENST00000300738.5
RRM1
ribonucleotide reductase M1
chrX_+_110339439 3.96 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr4_+_108910870 3.95 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
HADH
hydroxyacyl-CoA dehydrogenase
chr11_+_4116054 3.94 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr16_+_29911864 3.83 ENST00000308748.5
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr4_+_108911036 3.81 ENST00000505878.1
HADH
hydroxyacyl-CoA dehydrogenase
chrX_-_47479246 3.78 ENST00000295987.7
ENST00000340666.4
SYN1
synapsin I
chr17_+_8152590 3.70 ENST00000584044.1
ENST00000314666.6
ENST00000545834.1
ENST00000581242.1
PFAS
phosphoribosylformylglycinamidine synthase
chr6_-_31774714 3.61 ENST00000375661.5
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr22_+_32340447 3.56 ENST00000248975.5
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr20_+_42295745 3.47 ENST00000396863.4
ENST00000217026.4
MYBL2
v-myb avian myeloblastosis viral oncogene homolog-like 2
chr1_-_16482554 3.34 ENST00000358432.5
EPHA2
EPH receptor A2
chr17_+_7155343 3.32 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
ELP5
elongator acetyltransferase complex subunit 5
chr19_+_57831829 3.26 ENST00000321545.4
ZNF543
zinc finger protein 543
chrX_+_150148976 3.23 ENST00000419110.1
HMGB3
high mobility group box 3
chr11_-_28129656 3.22 ENST00000263181.6
KIF18A
kinesin family member 18A
chr4_-_146019335 3.20 ENST00000451299.2
ENST00000507656.1
ENST00000309439.5
ANAPC10
anaphase promoting complex subunit 10
chr18_+_2571510 3.18 ENST00000261597.4
ENST00000575515.1
NDC80
NDC80 kinetochore complex component
chr12_+_112856690 3.09 ENST00000392597.1
ENST00000351677.2
PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr4_+_85504075 3.08 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr11_-_1593150 3.03 ENST00000397374.3
DUSP8
dual specificity phosphatase 8
chr7_-_73153178 3.02 ENST00000437775.2
ENST00000222800.3
ABHD11
abhydrolase domain containing 11
chr19_+_8455200 3.02 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr9_-_99382065 2.99 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
CDC14B
cell division cycle 14B
chr3_+_44803209 2.98 ENST00000326047.4
KIF15
kinesin family member 15
chr16_+_56225248 2.96 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr20_+_5892037 2.94 ENST00000378961.4
CHGB
chromogranin B (secretogranin 1)
chr17_-_7165662 2.90 ENST00000571881.2
ENST00000360325.7
CLDN7
claudin 7
chr16_+_29911666 2.84 ENST00000563177.1
ENST00000483405.1
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr17_+_53342311 2.82 ENST00000226067.5
HLF
hepatic leukemia factor
chr19_+_8455077 2.77 ENST00000328024.6
RAB11B
RAB11B, member RAS oncogene family
chr11_-_33183006 2.73 ENST00000524827.1
ENST00000323959.4
ENST00000431742.2
CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr4_-_146019287 2.66 ENST00000502847.1
ENST00000513054.1
ANAPC10
anaphase promoting complex subunit 10
chr14_+_88851874 2.64 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr4_+_128802016 2.61 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
PLK4
polo-like kinase 4
chr5_-_138210977 2.60 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr10_+_123922941 2.57 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr19_-_10341948 2.57 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr11_+_18344106 2.53 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr4_+_75310851 2.49 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr11_+_3819049 2.46 ENST00000396986.2
ENST00000300730.6
ENST00000532535.1
ENST00000396993.4
ENST00000396991.2
ENST00000532523.1
ENST00000459679.1
ENST00000464261.1
ENST00000464906.2
ENST00000464441.1
PGAP2
post-GPI attachment to proteins 2
chr10_+_123923105 2.45 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr19_-_460996 2.43 ENST00000264554.6
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr2_-_240964716 2.38 ENST00000404554.1
ENST00000407129.3
ENST00000307300.4
ENST00000443626.1
ENST00000252711.2
NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr4_-_146019693 2.37 ENST00000514390.1
ANAPC10
anaphase promoting complex subunit 10
chr17_+_33914460 2.36 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr4_+_75311019 2.34 ENST00000502307.1
AREG
amphiregulin
chr19_+_18723660 2.33 ENST00000262817.3
TMEM59L
transmembrane protein 59-like
chr19_+_13056663 2.32 ENST00000541222.1
ENST00000316856.3
ENST00000586534.1
ENST00000592268.1
RAD23A
RAD23 homolog A (S. cerevisiae)
chr15_-_66790146 2.29 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr2_+_149632783 2.28 ENST00000435030.1
KIF5C
kinesin family member 5C
chr16_-_81040719 2.26 ENST00000219400.3
CMC2
C-x(9)-C motif containing 2
chr17_+_33914276 2.26 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr14_+_105219437 2.23 ENST00000329967.6
ENST00000347067.5
ENST00000553810.1
SIVA1
SIVA1, apoptosis-inducing factor
chr7_-_44924939 2.23 ENST00000395699.2
PURB
purine-rich element binding protein B
chr17_+_29421987 2.20 ENST00000431387.4
NF1
neurofibromin 1
chr19_+_35849362 2.19 ENST00000327809.4
FFAR3
free fatty acid receptor 3
chr17_+_29421900 2.16 ENST00000358273.4
ENST00000356175.3
NF1
neurofibromin 1
chr4_-_668108 2.16 ENST00000304312.4
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr10_+_123923205 2.14 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr11_-_123525289 2.13 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr1_-_16345245 2.11 ENST00000311890.9
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr17_+_43209967 2.11 ENST00000431281.1
ENST00000591859.1
ACBD4
acyl-CoA binding domain containing 4
chr19_+_45504688 2.10 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr7_-_140624499 2.07 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr7_+_140396946 2.06 ENST00000476470.1
ENST00000471136.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr19_+_52693259 2.02 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr1_-_1284730 2.02 ENST00000378888.5
DVL1
dishevelled segment polarity protein 1
chr9_-_131644202 1.98 ENST00000320665.6
ENST00000436267.2
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr2_-_220174166 1.95 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr7_+_100464760 1.94 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr3_+_170075436 1.93 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr19_+_36103631 1.93 ENST00000203166.5
ENST00000379045.2
HAUS5
HAUS augmin-like complex, subunit 5
chr1_+_70820451 1.91 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3
HERV-H LTR-associating 3
chr17_-_39780819 1.90 ENST00000311208.8
KRT17
keratin 17
chr7_+_140396756 1.88 ENST00000460088.1
ENST00000472695.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr3_+_158288999 1.84 ENST00000482628.1
ENST00000478894.2
ENST00000392822.3
ENST00000466246.1
MLF1
myeloid leukemia factor 1
chr20_+_34203794 1.82 ENST00000374273.3
SPAG4
sperm associated antigen 4
chr17_+_685513 1.79 ENST00000304478.4
RNMTL1
RNA methyltransferase like 1
chr15_+_75287861 1.76 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
SCAMP5
secretory carrier membrane protein 5
chr7_-_129592471 1.74 ENST00000473814.2
ENST00000490974.1
UBE2H
ubiquitin-conjugating enzyme E2H
chr5_+_131892603 1.73 ENST00000378823.3
ENST00000265335.6
RAD50
RAD50 homolog (S. cerevisiae)
chr19_+_36119929 1.73 ENST00000588161.1
ENST00000262633.4
ENST00000592202.1
ENST00000586618.1
RBM42
RNA binding motif protein 42
chr1_-_70671216 1.72 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr19_+_50180317 1.70 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr11_+_82783097 1.68 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
RAB30-AS1
RAB30 antisense RNA 1 (head to head)
chr17_+_68071458 1.68 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_+_41476327 1.68 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr20_-_3154162 1.67 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr2_-_224467093 1.67 ENST00000305409.2
SCG2
secretogranin II
chr19_-_56826157 1.64 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
ZSCAN5A
zinc finger and SCAN domain containing 5A
chr19_+_36119975 1.64 ENST00000589559.1
ENST00000360475.4
RBM42
RNA binding motif protein 42
chr12_-_58165870 1.59 ENST00000257848.7
METTL1
methyltransferase like 1
chr22_+_25003626 1.58 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1
gamma-glutamyltransferase 1
chr4_+_75480629 1.58 ENST00000380846.3
AREGB
amphiregulin B
chr6_+_28048753 1.57 ENST00000377325.1
ZNF165
zinc finger protein 165
chr4_-_2010562 1.57 ENST00000411649.1
ENST00000542778.1
ENST00000411638.2
ENST00000431323.1
NELFA
negative elongation factor complex member A
chr2_-_114514181 1.56 ENST00000409342.1
SLC35F5
solute carrier family 35, member F5
chr19_-_8008533 1.56 ENST00000597926.1
TIMM44
translocase of inner mitochondrial membrane 44 homolog (yeast)
chr1_-_202896310 1.54 ENST00000367261.3
KLHL12
kelch-like family member 12
chr11_-_31839488 1.54 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6
paired box 6
chr11_+_66610883 1.52 ENST00000309657.3
ENST00000524506.1
RCE1
Ras converting CAAX endopeptidase 1
chr12_-_93836028 1.51 ENST00000318066.2
UBE2N
ubiquitin-conjugating enzyme E2N
chr12_-_93835665 1.51 ENST00000552442.1
ENST00000550657.1
UBE2N
ubiquitin-conjugating enzyme E2N
chr9_-_2844058 1.51 ENST00000397885.2
KIAA0020
KIAA0020
chr11_-_62389449 1.50 ENST00000534026.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr9_-_131644306 1.49 ENST00000302586.3
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr9_-_33001520 1.48 ENST00000463596.1
ENST00000379819.1
ENST00000397172.3
ENST00000379812.5
ENST00000477119.1
ENST00000379813.3
ENST00000379825.2
ENST00000309615.3
ENST00000476858.1
ENST00000473221.1
APTX
aprataxin
chr17_+_68071389 1.47 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_+_36486078 1.47 ENST00000378887.2
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr1_-_115124257 1.46 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr4_+_159131346 1.46 ENST00000508243.1
ENST00000296529.6
TMEM144
transmembrane protein 144
chr12_-_56694142 1.46 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr14_+_96671016 1.43 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2
RP11-404P21.8
bradykinin receptor B2
Uncharacterized protein
chr14_+_93651296 1.43 ENST00000283534.4
ENST00000557574.1
TMEM251
RP11-371E8.4
transmembrane protein 251
Uncharacterized protein
chr14_+_93651358 1.41 ENST00000415050.2
TMEM251
transmembrane protein 251
chr10_-_97416400 1.40 ENST00000371224.2
ENST00000371221.3
ALDH18A1
aldehyde dehydrogenase 18 family, member A1
chr3_+_158288942 1.38 ENST00000491767.1
ENST00000355893.5
MLF1
myeloid leukemia factor 1
chr10_+_134351319 1.37 ENST00000368594.3
ENST00000368593.3
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr3_+_158288960 1.37 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
MLF1
myeloid leukemia factor 1
chr19_+_44100632 1.37 ENST00000533118.1
ZNF576
zinc finger protein 576
chr6_+_27833034 1.35 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr1_+_28655505 1.35 ENST00000373842.4
ENST00000398997.2
MED18
mediator complex subunit 18
chr8_-_82754427 1.34 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
SNX16
sorting nexin 16
chr3_-_187388173 1.34 ENST00000287641.3
SST
somatostatin
chr3_-_107941230 1.33 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr3_+_62304712 1.33 ENST00000494481.1
C3orf14
chromosome 3 open reading frame 14
chr9_-_111696340 1.29 ENST00000374647.5
IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr7_-_31380502 1.29 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr1_-_23495340 1.29 ENST00000418342.1
LUZP1
leucine zipper protein 1
chr21_+_45209394 1.28 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr12_+_7014064 1.23 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr12_+_7013897 1.22 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr10_-_27444143 1.20 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr11_+_108535752 1.20 ENST00000322536.3
DDX10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr4_-_186456652 1.18 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chr15_-_66790047 1.17 ENST00000566658.1
ENST00000563480.2
ENST00000395589.2
ENST00000307979.7
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr4_+_1873100 1.16 ENST00000508803.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr1_+_110527308 1.15 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr2_+_3705785 1.15 ENST00000252505.3
ALLC
allantoicase
chr7_+_23221438 1.15 ENST00000258742.5
NUPL2
nucleoporin like 2
chr9_-_99381660 1.15 ENST00000375240.3
ENST00000463569.1
CDC14B
cell division cycle 14B
chr11_-_13517565 1.14 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr7_+_140396465 1.14 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr9_+_97488939 1.13 ENST00000277198.2
ENST00000297979.5
C9orf3
chromosome 9 open reading frame 3
chr3_+_62304648 1.12 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chrX_-_7895755 1.11 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
PNPLA4
patatin-like phospholipase domain containing 4
chr19_+_36036583 1.10 ENST00000392205.1
TMEM147
transmembrane protein 147
chr11_-_68039364 1.09 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
C11orf24
chromosome 11 open reading frame 24
chr16_+_19079311 1.09 ENST00000569127.1
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr4_-_79860506 1.08 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr10_+_35484793 1.07 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr3_-_48130707 1.06 ENST00000360240.6
ENST00000383737.4
MAP4
microtubule-associated protein 4
chr16_-_3068171 1.05 ENST00000572154.1
ENST00000328796.4
CLDN6
claudin 6
chr17_+_41177220 1.05 ENST00000587250.2
ENST00000544533.1
RND2
Rho family GTPase 2
chr4_-_186456766 1.04 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr12_+_132628963 1.03 ENST00000330579.1
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr19_+_36120009 1.01 ENST00000589871.1
RBM42
RNA binding motif protein 42
chr2_-_220408430 1.00 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr4_+_668348 1.00 ENST00000511290.1
MYL5
myosin, light chain 5, regulatory
chr18_+_23806437 0.99 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr1_+_17531614 0.99 ENST00000375471.4
PADI1
peptidyl arginine deiminase, type I
chr9_-_111696224 0.98 ENST00000537196.1
IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr3_-_119182523 0.97 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr19_+_57874835 0.95 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
TRAPPC2P1
ZNF547
AC003002.4
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr22_+_31518938 0.95 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr1_+_2005425 0.94 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr7_-_129592700 0.94 ENST00000472396.1
ENST00000355621.3
UBE2H
ubiquitin-conjugating enzyme E2H
chr12_-_121454148 0.94 ENST00000535367.1
ENST00000538296.1
ENST00000445832.3
ENST00000536407.2
ENST00000366211.2
ENST00000539736.1
ENST00000288757.3
ENST00000537817.1
C12orf43
chromosome 12 open reading frame 43
chr6_-_26285737 0.93 ENST00000377727.1
ENST00000289352.1
HIST1H4H
histone cluster 1, H4h
chr2_-_21022818 0.93 ENST00000440866.2
ENST00000541941.1
ENST00000402479.2
ENST00000435420.2
ENST00000432947.1
ENST00000403006.2
ENST00000419825.2
ENST00000381090.3
ENST00000237822.3
ENST00000412261.1
C2orf43
chromosome 2 open reading frame 43
chr1_+_6684918 0.92 ENST00000054650.4
THAP3
THAP domain containing, apoptosis associated protein 3
chr19_+_49122548 0.92 ENST00000245222.4
ENST00000340932.3
ENST00000601712.1
ENST00000600537.1
SPHK2
sphingosine kinase 2
chr7_-_124569991 0.92 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1
protection of telomeres 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.5 GO:0009386 translational attenuation(GO:0009386)
1.5 6.1 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
1.5 4.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
1.4 4.1 GO:1901899 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
1.1 3.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.0 7.9 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.9 4.6 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.8 4.9 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.8 3.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.7 6.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.7 4.4 GO:0030035 microspike assembly(GO:0030035)
0.7 2.8 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.7 2.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.6 1.9 GO:1990502 dense core granule maturation(GO:1990502)
0.6 2.6 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.6 13.5 GO:0051231 spindle elongation(GO:0051231)
0.6 4.8 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.6 5.8 GO:0045054 constitutive secretory pathway(GO:0045054)
0.6 1.7 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.5 2.6 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.5 1.6 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.5 7.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.4 3.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.4 4.8 GO:0000050 urea cycle(GO:0000050)
0.4 1.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.4 3.8 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.4 1.9 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.4 1.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.4 1.2 GO:0043605 cellular amide catabolic process(GO:0043605)
0.4 1.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.4 2.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.4 3.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.4 3.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.4 3.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.3 7.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 12.8 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.3 6.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 1.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 2.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3 2.4 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.3 2.6 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.3 4.2 GO:0031268 pseudopodium organization(GO:0031268)
0.3 1.6 GO:0051012 microtubule sliding(GO:0051012)
0.3 7.1 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.3 2.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 10.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 1.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 3.0 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.2 3.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 1.6 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.2 0.7 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2 2.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 0.6 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.2 0.4 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 15.6 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 0.6 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2 7.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.2 1.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 0.2 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) deoxyribonucleoside diphosphate metabolic process(GO:0009186) dGDP metabolic process(GO:0046066)
0.2 5.7 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.4 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.2 1.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.5 GO:0000012 single strand break repair(GO:0000012)
0.2 5.9 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.2 1.9 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.2 3.0 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 4.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 4.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 2.0 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0043335 protein unfolding(GO:0043335)
0.1 1.8 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:0046878 regulation of saliva secretion(GO:0046877) positive regulation of saliva secretion(GO:0046878)
0.1 1.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 7.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 1.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.3 GO:0001842 neural fold formation(GO:0001842)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 3.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.9 GO:0051096 telomere assembly(GO:0032202) positive regulation of helicase activity(GO:0051096)
0.1 1.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 2.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 2.7 GO:0006379 mRNA cleavage(GO:0006379)
0.1 3.6 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 0.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.5 GO:0034650 aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342) cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.1 0.7 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 7.2 GO:0021987 cerebral cortex development(GO:0021987)
0.1 3.4 GO:0031648 protein destabilization(GO:0031648)
0.1 4.6 GO:0021762 substantia nigra development(GO:0021762)
0.1 2.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 4.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 2.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 3.1 GO:0010107 potassium ion import(GO:0010107)
0.1 2.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.3 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.6 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 1.3 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 3.5 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.0 1.9 GO:0033108 mitochondrial respiratory chain complex assembly(GO:0033108)
0.0 1.5 GO:0007507 heart development(GO:0007507)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.3 GO:0021542 dentate gyrus development(GO:0021542)
0.0 1.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 1.3 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 1.5 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 1.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 1.1 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.7 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 1.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.9 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 1.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.0 GO:0051031 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 1.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 2.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 1.0 GO:0048477 oogenesis(GO:0048477)
0.0 0.5 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 2.2 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 3.2 GO:0006310 DNA recombination(GO:0006310)
0.0 1.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.4 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 1.4 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 2.1 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.9 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 2.2 GO:0045637 regulation of myeloid cell differentiation(GO:0045637)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 14.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
2.0 6.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
2.0 7.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.5 4.4 GO:0044393 microspike(GO:0044393)
1.2 10.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.2 3.5 GO:0031523 Myb complex(GO:0031523)
1.1 3.2 GO:0031262 Ndc80 complex(GO:0031262)
1.0 3.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
1.0 3.0 GO:0005873 plus-end kinesin complex(GO:0005873)
0.9 2.6 GO:0098536 deuterosome(GO:0098536)
0.7 7.3 GO:0070938 contractile ring(GO:0070938)
0.7 8.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.7 6.7 GO:0000439 core TFIIH complex(GO:0000439)
0.5 3.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.4 1.9 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.3 1.0 GO:0030689 Noc complex(GO:0030689)
0.3 1.6 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 1.6 GO:0032021 NELF complex(GO:0032021)
0.3 9.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.3 11.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 8.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 1.4 GO:0070847 core mediator complex(GO:0070847)
0.3 1.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 1.7 GO:0030870 Mre11 complex(GO:0030870)
0.2 3.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 4.6 GO:0036020 endolysosome membrane(GO:0036020)
0.2 4.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 4.1 GO:0042583 chromaffin granule(GO:0042583)
0.2 1.4 GO:0045179 apical cortex(GO:0045179)
0.2 2.3 GO:0035253 ciliary rootlet(GO:0035253)
0.2 4.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 2.0 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 11.6 GO:0005811 lipid particle(GO:0005811)
0.1 2.3 GO:0034709 methylosome(GO:0034709)
0.1 2.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 2.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 4.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.9 GO:0070187 telosome(GO:0070187)
0.1 3.8 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 7.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.3 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.6 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 7.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.7 GO:0031045 dense core granule(GO:0031045)
0.1 7.4 GO:0014704 intercalated disc(GO:0014704)
0.1 2.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 3.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.2 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1 6.2 GO:0072686 mitotic spindle(GO:0072686)
0.1 4.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 3.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 3.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0 2.3 GO:0016235 aggresome(GO:0016235)
0.0 1.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 3.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 15.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 3.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.3 GO:0000502 proteasome complex(GO:0000502)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 4.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 1.9 GO:0043679 axon terminus(GO:0043679)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 2.8 GO:0001726 ruffle(GO:0001726)
0.0 4.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 6.1 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
2.0 7.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.2 4.9 GO:0043515 kinetochore binding(GO:0043515)
1.0 3.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.9 18.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.6 1.9 GO:0004947 bradykinin receptor activity(GO:0004947)
0.6 1.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 7.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 2.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 2.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4 7.8 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.4 10.0 GO:0031489 myosin V binding(GO:0031489)
0.4 2.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.4 1.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 4.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 1.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 7.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 1.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 7.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 6.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 1.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 1.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 12.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 3.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.3 1.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.3 5.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 3.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 1.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 2.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.2 2.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 0.7 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.2 1.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.2 0.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 4.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.2 3.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 4.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 2.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 5.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.5 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.2 3.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 4.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 3.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 7.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 2.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 7.0 GO:0019894 kinesin binding(GO:0019894)
0.1 0.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 6.1 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 2.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 2.1 GO:0031005 filamin binding(GO:0031005)
0.1 1.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 4.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 2.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 4.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 2.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 1.1 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.9 GO:0030507 spectrin binding(GO:0030507)
0.1 3.5 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 6.7 GO:0051213 dioxygenase activity(GO:0051213)
0.1 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 2.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 4.3 GO:0019843 rRNA binding(GO:0019843)
0.1 2.0 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.5 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 6.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 6.0 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 1.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 6.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 4.4 GO:0008144 drug binding(GO:0008144)
0.0 1.5 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 2.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 3.0 GO:0004497 monooxygenase activity(GO:0004497)
0.0 2.1 GO:0046332 SMAD binding(GO:0046332)
0.0 2.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 2.7 GO:0005179 hormone activity(GO:0005179)
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 5.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 4.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 2.7 GO:0003924 GTPase activity(GO:0003924)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 21.3 PID PLK1 PATHWAY PLK1 signaling events
0.2 7.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 6.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 9.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 5.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 12.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 8.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 3.8 PID IL5 PATHWAY IL5-mediated signaling events
0.2 5.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 11.5 PID E2F PATHWAY E2F transcription factor network
0.1 3.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 1.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.7 PID ATM PATHWAY ATM pathway
0.1 2.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 3.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 14.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 9.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.3 8.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.3 3.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 3.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 4.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 6.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 3.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 7.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 5.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 4.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 5.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 4.5 REACTOME KINESINS Genes involved in Kinesins
0.2 2.4 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.2 4.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 3.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 2.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 7.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 6.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 4.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 3.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 7.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 3.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 3.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 5.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 4.2 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling