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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for BARHL1

Z-value: 1.13

Motif logo

Transcription factors associated with BARHL1

Gene Symbol Gene ID Gene Info
ENSG00000125492.5 BarH like homeobox 1

Activity profile of BARHL1 motif

Sorted Z-values of BARHL1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_68665084 35.84 ENST00000509462.1
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr19_-_14945933 32.99 ENST00000322301.3
olfactory receptor, family 7, subfamily A, member 5
chr12_+_104682496 31.36 ENST00000378070.4
thioredoxin reductase 1
chr18_+_657578 30.04 ENST00000323274.10
thymidylate synthetase
chr3_-_107777208 29.76 ENST00000398258.3
CD47 molecule
chr1_-_145826450 29.33 ENST00000462900.2
G protein-coupled receptor 89A
chr14_+_56127989 29.07 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr13_+_48611665 28.62 ENST00000258662.2
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr15_+_65843130 27.86 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr12_+_104337515 27.27 ENST00000550595.1
heat shock protein 90kDa beta (Grp94), member 1
chr17_-_40288449 26.95 ENST00000552162.1
ENST00000550504.1
RAB5C, member RAS oncogene family
chr2_+_86426478 26.77 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
mitochondrial ribosomal protein L35
chr11_+_114310164 26.51 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr19_+_47634039 25.85 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr12_+_108079664 25.77 ENST00000541166.1
PWP1 homolog (S. cerevisiae)
chr14_+_78174414 25.75 ENST00000557342.1
ENST00000238688.5
ENST00000557623.1
ENST00000557431.1
ENST00000556831.1
ENST00000556375.1
ENST00000553981.1
SRA stem-loop interacting RNA binding protein
chr18_+_657733 25.44 ENST00000323250.5
ENST00000323224.7
thymidylate synthetase
chr20_-_54967187 25.41 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
aurora kinase A
chr18_-_33702078 25.25 ENST00000586829.1
solute carrier family 39 (zinc transporter), member 6
chr17_-_73150629 25.23 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
hematological and neurological expressed 1
chr6_-_150067696 24.81 ENST00000340413.2
ENST00000367403.3
nucleoporin 43kDa
chr15_+_66797455 24.49 ENST00000446801.2
zwilch kinetochore protein
chr4_-_174256276 24.05 ENST00000296503.5
high mobility group box 2
chr4_+_113558612 23.81 ENST00000505034.1
ENST00000324052.6
La ribonucleoprotein domain family, member 7
chr5_+_159848854 23.73 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr2_-_152146385 23.73 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr8_+_55047763 23.00 ENST00000260102.4
ENST00000519831.1
mitochondrial ribosomal protein L15
chr22_+_42017987 22.36 ENST00000405506.1
X-ray repair complementing defective repair in Chinese hamster cells 6
chr13_-_24007815 22.08 ENST00000382298.3
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr5_+_159848807 21.94 ENST00000352433.5
pituitary tumor-transforming 1
chr5_+_162887556 21.92 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
hyaluronan-mediated motility receptor (RHAMM)
chr5_+_112196919 21.89 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
signal recognition particle 19kDa
chrX_-_15511438 21.78 ENST00000380420.5
pirin (iron-binding nuclear protein)
chr8_-_109260897 21.70 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
eukaryotic translation initiation factor 3, subunit E
chr3_+_172468472 21.69 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr17_-_38574169 21.58 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr4_-_143227088 21.51 ENST00000511838.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr15_+_66797627 21.10 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr2_+_187371440 21.08 ENST00000445547.1
zinc finger CCCH-type containing 15
chr1_-_193075180 20.87 ENST00000367440.3
glutaredoxin 2
chr3_-_64009658 20.31 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr3_+_138340049 20.23 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr3_+_139063372 20.08 ENST00000478464.1
mitochondrial ribosomal protein S22
chrX_+_69509927 20.01 ENST00000374403.3
kinesin family member 4A
chr3_+_180630090 19.66 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr17_-_47492164 19.43 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
prohibitin
chr9_+_108463234 19.42 ENST00000374688.1
transmembrane protein 38B
chr1_+_165864800 19.31 ENST00000469256.2
uridine-cytidine kinase 2
chr11_+_101983176 19.19 ENST00000524575.1
Yes-associated protein 1
chr10_+_62538089 18.86 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr6_-_150067632 18.74 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
nucleoporin 43kDa
chr7_-_87856280 18.74 ENST00000490437.1
ENST00000431660.1
sorcin
chr3_-_185641681 18.67 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chr4_-_122744998 18.50 ENST00000274026.5
cyclin A2
chr11_+_114310102 18.31 ENST00000265881.5
RNA exonuclease 2
chr4_-_174255536 18.22 ENST00000446922.2
high mobility group box 2
chr7_+_107224364 18.11 ENST00000491150.1
B-cell receptor-associated protein 29
chr7_-_87856303 18.10 ENST00000394641.3
sorcin
chr15_-_59949693 17.98 ENST00000396063.1
ENST00000396064.3
ENST00000484743.1
ENST00000559706.1
ENST00000396060.2
general transcription factor IIA, 2, 12kDa
chr11_+_35201826 17.97 ENST00000531873.1
CD44 molecule (Indian blood group)
chr4_+_107236692 17.96 ENST00000510207.1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr13_+_37581115 17.96 ENST00000481013.1
exosome component 8
chr5_-_43557791 17.79 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
poly(A) binding protein interacting protein 1
chr12_-_110883346 17.77 ENST00000547365.1
actin related protein 2/3 complex, subunit 3, 21kDa
chr14_-_58893832 17.76 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr18_+_55816546 17.73 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr15_-_59949667 17.57 ENST00000396061.1
general transcription factor IIA, 2, 12kDa
chr20_+_11898507 17.54 ENST00000378226.2
BTB (POZ) domain containing 3
chr17_+_34842512 17.48 ENST00000588253.1
ENST00000592616.1
ENST00000590858.1
ENST00000588357.1
zinc finger, HIT-type containing 3
chr16_+_81070792 17.43 ENST00000564241.1
ENST00000565237.1
ATM interactor
chr3_-_183967296 17.34 ENST00000455059.1
ENST00000445626.2
ALG3, alpha-1,3- mannosyltransferase
chr3_-_149293990 17.21 ENST00000472417.1
WW domain containing transcription regulator 1
chr17_-_62658186 17.18 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr8_-_101962777 17.16 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr5_+_68462837 17.08 ENST00000256442.5
cyclin B1
chr7_+_56019486 17.07 ENST00000446692.1
ENST00000285298.4
ENST00000443449.1
glioblastoma amplified sequence
mitochondrial ribosomal protein S17
chr14_+_20811766 17.02 ENST00000250416.5
ENST00000527915.1
poly (ADP-ribose) polymerase 2
chr14_+_73563735 17.02 ENST00000532192.1
RNA binding motif protein 25
chr5_+_167913450 16.92 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chr2_-_176046391 16.89 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr21_-_35284635 16.78 ENST00000429238.1
AP000304.12
chr8_-_124428569 16.75 ENST00000521903.1
ATPase family, AAA domain containing 2
chr1_-_70671216 16.65 ENST00000370952.3
leucine rich repeat containing 40
chr9_-_127177703 16.56 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
proteasome (prosome, macropain) subunit, beta type, 7
chr3_+_160117087 16.48 ENST00000357388.3
structural maintenance of chromosomes 4
chr1_+_165864821 16.45 ENST00000470820.1
uridine-cytidine kinase 2
chr8_-_49834299 16.45 ENST00000396822.1
snail family zinc finger 2
chr17_+_34842473 16.37 ENST00000490126.2
ENST00000225410.4
zinc finger, HIT-type containing 3
chr2_+_65454926 16.33 ENST00000542850.1
ENST00000377982.4
ARP2 actin-related protein 2 homolog (yeast)
chr8_-_97247759 16.32 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
ubiquinol-cytochrome c reductase binding protein
chr16_-_58163299 16.28 ENST00000262498.3
chromosome 16 open reading frame 80
chr20_+_25388293 16.24 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr17_+_66521936 16.18 ENST00000592800.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr7_-_123197733 16.13 ENST00000470123.1
ENST00000471770.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr1_+_145883868 16.11 ENST00000447947.2
G protein-coupled receptor 89C
chr8_+_11666649 16.06 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr6_+_80714318 16.03 ENST00000369798.2
TTK protein kinase
chr7_-_97501733 15.94 ENST00000444334.1
ENST00000422745.1
ENST00000394308.3
ENST00000451771.1
ENST00000175506.4
asparagine synthetase (glutamine-hydrolyzing)
chr2_+_172778952 15.92 ENST00000392584.1
ENST00000264108.4
histone acetyltransferase 1
chr13_+_98605902 15.82 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
importin 5
chr11_-_47447970 15.73 ENST00000298852.3
ENST00000530912.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr2_+_27435734 15.69 ENST00000419744.1
all-trans retinoic acid-induced differentiation factor
chr2_+_170655322 15.64 ENST00000260956.4
ENST00000417292.1
Sjogren syndrome antigen B (autoantigen La)
chr1_-_246357029 15.52 ENST00000391836.2
SET and MYND domain containing 3
chr8_+_104310661 15.48 ENST00000522566.1
frizzled family receptor 6
chr17_-_17184605 15.46 ENST00000268717.5
COP9 signalosome subunit 3
chr1_-_89357179 15.34 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chr14_+_35761580 15.32 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr17_+_35851570 15.27 ENST00000394386.1
dual specificity phosphatase 14
chr9_+_116037922 15.25 ENST00000374198.4
pre-mRNA processing factor 4
chrX_+_114827818 15.24 ENST00000420625.2
plastin 3
chr2_+_118572226 15.17 ENST00000263239.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr12_-_76462713 15.16 ENST00000552056.1
nucleosome assembly protein 1-like 1
chr5_-_140070897 15.14 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
histidyl-tRNA synthetase
chr10_+_47894023 15.03 ENST00000358474.5
family with sequence similarity 21, member B
chr6_-_79944336 14.96 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chrX_-_118986911 14.92 ENST00000276201.2
ENST00000345865.2
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr17_+_48823975 14.87 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr14_-_23398565 14.86 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
protein arginine methyltransferase 5
chr22_-_32808194 14.86 ENST00000451746.2
ENST00000216038.5
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr1_+_29063119 14.80 ENST00000474884.1
ENST00000542507.1
YTH domain family, member 2
chr10_-_95242044 14.77 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr5_-_77072145 14.75 ENST00000380377.4
tubulin folding cofactor A
chr8_-_80942139 14.72 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
mitochondrial ribosomal protein S28
chr3_-_149093499 14.71 ENST00000472441.1
transmembrane 4 L six family member 1
chr12_+_53693812 14.69 ENST00000549488.1
chromosome 12 open reading frame 10
chr2_-_151344172 14.59 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr14_+_51706886 14.55 ENST00000457354.2
thioredoxin-related transmembrane protein 1
chr4_+_57301896 14.48 ENST00000514888.1
ENST00000264221.2
ENST00000505164.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr12_+_69979210 14.38 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr17_+_73230799 14.36 ENST00000579838.1
nucleoporin 85kDa
chr9_-_69229650 14.34 ENST00000416428.1
COBW domain containing 6
chr3_+_184018352 14.33 ENST00000435761.1
ENST00000439383.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr17_-_65362678 14.22 ENST00000357146.4
ENST00000356126.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr4_-_143226979 14.21 ENST00000514525.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_+_155110956 14.21 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
vesicle-associated membrane protein 7
chr17_+_56769924 14.15 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51 paralog C
chr12_-_71551652 14.04 ENST00000546561.1
tetraspanin 8
chr7_+_98923505 14.04 ENST00000432884.2
ENST00000262942.5
actin related protein 2/3 complex, subunit 1A, 41kDa
chr8_+_101162812 13.99 ENST00000353107.3
ENST00000522439.1
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr3_+_23851928 13.92 ENST00000467766.1
ENST00000424381.1
ubiquitin-conjugating enzyme E2E 1
chr22_-_30987849 13.90 ENST00000402284.3
ENST00000354694.7
pescadillo ribosomal biogenesis factor 1
chr2_-_32236002 13.88 ENST00000404530.1
mediator of cell motility 1
chr1_+_225965518 13.79 ENST00000304786.7
ENST00000366839.4
ENST00000366838.1
signal recognition particle 9kDa
chr8_-_80942061 13.75 ENST00000519386.1
mitochondrial ribosomal protein S28
chr3_-_195808952 13.74 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
transferrin receptor
chr10_-_127505167 13.72 ENST00000368786.1
uroporphyrinogen III synthase
chr7_+_2394445 13.71 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
eukaryotic translation initiation factor 3, subunit B
chr7_+_96745902 13.70 ENST00000432641.2
ACN9 homolog (S. cerevisiae)
chr3_+_45017722 13.69 ENST00000265564.7
exosome component 7
chrX_+_19373700 13.66 ENST00000379804.1
pyruvate dehydrogenase (lipoamide) alpha 1
chr15_+_78832747 13.63 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr6_-_3157760 13.51 ENST00000333628.3
tubulin, beta 2A class IIa
chr9_+_138391805 13.50 ENST00000371785.1
mitochondrial ribosomal protein S2
chr4_-_103746683 13.47 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr21_-_43346790 13.46 ENST00000329623.7
C2 calcium-dependent domain containing 2
chr2_-_225811747 13.33 ENST00000409592.3
dedicator of cytokinesis 10
chr20_+_36405665 13.31 ENST00000373469.1
catenin, beta like 1
chrX_+_119737806 13.28 ENST00000371317.5
malignant T cell amplified sequence 1
chr3_-_49066811 13.25 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr14_+_39583427 13.23 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
gem (nuclear organelle) associated protein 2
chr11_-_82997420 13.23 ENST00000455220.2
ENST00000529689.1
coiled-coil domain containing 90B
chr13_+_34392185 13.20 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr1_-_28527152 13.14 ENST00000321830.5
Uncharacterized protein
chr2_-_150444116 13.10 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr12_+_56435637 13.09 ENST00000356464.5
ENST00000552361.1
ribosomal protein S26
chr16_-_23607598 13.07 ENST00000562133.1
ENST00000570319.1
ENST00000007516.3
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr2_-_169769787 13.06 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr3_-_57583185 12.94 ENST00000463880.1
ADP-ribosylation factor 4
chr4_+_57302297 12.94 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr2_-_170681324 12.90 ENST00000409340.1
methyltransferase like 5
chr12_+_69979113 12.85 ENST00000299300.6
chaperonin containing TCP1, subunit 2 (beta)
chr5_+_172385732 12.83 ENST00000519974.1
ENST00000521476.1
ribosomal protein L26-like 1
chr4_+_17616253 12.82 ENST00000237380.7
mediator complex subunit 28
chr3_+_141144954 12.78 ENST00000441582.2
ENST00000321464.5
zinc finger and BTB domain containing 38
chr15_+_40453204 12.78 ENST00000287598.6
ENST00000412359.3
BUB1 mitotic checkpoint serine/threonine kinase B
chr3_+_150321068 12.77 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
Selenoprotein T
chr1_+_53480598 12.75 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr1_-_151735937 12.75 ENST00000368829.3
ENST00000368830.3
mitochondrial ribosomal protein L9
chr21_-_30445886 12.72 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
chaperonin containing TCP1, subunit 8 (theta)
chr15_+_59397298 12.72 ENST00000559622.1
cyclin B2
chr2_-_190044480 12.70 ENST00000374866.3
collagen, type V, alpha 2
chr22_-_29107919 12.68 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr8_+_128748466 12.64 ENST00000524013.1
ENST00000520751.1
v-myc avian myelocytomatosis viral oncogene homolog
chr2_-_225362533 12.64 ENST00000451538.1
cullin 3
chr8_+_21823726 12.63 ENST00000433566.4
exportin 7
chr19_-_42806919 12.62 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr2_-_44223138 12.59 ENST00000260665.7
leucine-rich pentatricopeptide repeat containing
chr16_+_84801852 12.59 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr20_-_43133491 12.55 ENST00000411544.1
serine incorporator 3
chr9_+_106856831 12.53 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr22_+_19467261 12.48 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
cell division cycle 45
chr3_-_195808980 12.46 ENST00000360110.4
transferrin receptor
chr2_+_65454863 12.45 ENST00000260641.5
ARP2 actin-related protein 2 homolog (yeast)
chr5_+_115420688 12.40 ENST00000274458.4
COMM domain containing 10
chr8_+_42249418 12.39 ENST00000521158.1
ENST00000022615.4
voltage-dependent anion channel 3
chr8_-_48872686 12.37 ENST00000314191.2
ENST00000338368.3
protein kinase, DNA-activated, catalytic polypeptide
chr3_-_141719195 12.32 ENST00000397991.4
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_169746878 12.32 ENST00000282074.2
SPC25, NDC80 kinetochore complex component
chr15_+_57511609 12.31 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
transcription factor 12

Network of associatons between targets according to the STRING database.

First level regulatory network of BARHL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
13.9 55.5 GO:0019860 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
12.7 38.0 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
9.7 38.9 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
9.6 28.8 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
9.1 27.2 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
9.0 26.9 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
8.9 35.8 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
8.7 26.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
8.5 25.4 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
8.1 40.6 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
7.9 31.7 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
7.9 7.9 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
7.9 23.7 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
7.6 22.8 GO:0006597 spermine biosynthetic process(GO:0006597)
7.3 21.9 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
7.2 28.6 GO:0006203 dGTP catabolic process(GO:0006203)
6.7 26.7 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
6.4 19.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
6.4 19.3 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
6.2 18.5 GO:0002188 translation reinitiation(GO:0002188)
6.1 30.7 GO:0016321 female meiosis chromosome segregation(GO:0016321)
6.1 30.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
6.1 24.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
6.0 17.9 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
5.8 28.8 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
5.7 17.1 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
5.7 22.7 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
5.6 16.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
5.6 16.7 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
5.5 38.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
5.4 32.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
5.1 20.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
5.1 30.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
5.1 35.6 GO:0043985 histone H4-R3 methylation(GO:0043985)
5.0 25.0 GO:1990034 calcium ion export from cell(GO:1990034)
4.9 29.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
4.7 14.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
4.7 18.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
4.6 13.9 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
4.6 18.5 GO:0071314 cellular response to cocaine(GO:0071314)
4.6 13.8 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
4.6 73.1 GO:0000338 protein deneddylation(GO:0000338)
4.5 13.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
4.5 13.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
4.4 26.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
4.4 26.4 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
4.4 35.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
4.4 74.2 GO:0006265 DNA topological change(GO:0006265)
4.3 21.7 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
4.3 21.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
4.3 17.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
4.3 17.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
4.2 12.7 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
4.2 33.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
4.2 8.4 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
4.1 20.7 GO:0030047 actin modification(GO:0030047)
4.1 12.3 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
3.9 35.0 GO:0001887 selenium compound metabolic process(GO:0001887)
3.9 27.2 GO:0042262 DNA protection(GO:0042262)
3.9 11.6 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
3.8 34.6 GO:1902969 mitotic DNA replication(GO:1902969)
3.7 22.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
3.7 22.4 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
3.6 7.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
3.6 10.8 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
3.5 10.6 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
3.5 3.5 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
3.5 20.8 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
3.5 44.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
3.4 13.7 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
3.3 10.0 GO:0007518 myoblast fate determination(GO:0007518)
3.2 9.6 GO:0007113 endomitotic cell cycle(GO:0007113)
3.2 9.6 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
3.2 16.0 GO:0032790 ribosome disassembly(GO:0032790)
3.2 6.4 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
3.2 12.7 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
3.1 9.4 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
3.1 230.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
3.1 12.4 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
3.1 21.7 GO:1902416 positive regulation of mRNA binding(GO:1902416)
3.0 15.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
3.0 35.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
3.0 17.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
3.0 14.9 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
3.0 11.9 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
2.9 8.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
2.9 14.4 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
2.9 40.3 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
2.9 28.7 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
2.8 22.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.8 19.8 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
2.8 8.5 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
2.8 11.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
2.8 2.8 GO:0072289 metanephric nephron tubule formation(GO:0072289)
2.8 27.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
2.7 11.0 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
2.7 10.9 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
2.7 8.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
2.7 10.8 GO:0072683 T cell extravasation(GO:0072683)
2.7 8.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
2.7 18.7 GO:0009597 detection of virus(GO:0009597)
2.7 8.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
2.7 16.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
2.6 26.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.6 13.2 GO:0006740 NADPH regeneration(GO:0006740)
2.6 7.9 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
2.6 23.7 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
2.6 15.7 GO:1904798 positive regulation of core promoter binding(GO:1904798)
2.6 10.5 GO:0015866 ADP transport(GO:0015866)
2.6 23.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
2.6 10.4 GO:0035511 oxidative DNA demethylation(GO:0035511)
2.6 10.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.6 7.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
2.6 12.8 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
2.5 22.9 GO:0070487 monocyte aggregation(GO:0070487)
2.5 17.7 GO:0075525 viral translational termination-reinitiation(GO:0075525)
2.5 12.6 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
2.5 25.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
2.5 27.6 GO:0045176 apical protein localization(GO:0045176)
2.5 7.4 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
2.4 24.4 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
2.4 14.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
2.4 38.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
2.4 4.8 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
2.4 4.7 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
2.3 7.0 GO:1901143 insulin catabolic process(GO:1901143)
2.3 16.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
2.3 2.3 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
2.3 7.0 GO:0014016 neuroblast differentiation(GO:0014016)
2.3 11.5 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
2.3 13.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
2.3 4.5 GO:0035927 RNA import into mitochondrion(GO:0035927)
2.3 4.5 GO:1903722 regulation of centriole elongation(GO:1903722)
2.2 6.7 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
2.2 6.7 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
2.2 4.5 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
2.2 13.3 GO:0006177 GMP biosynthetic process(GO:0006177)
2.2 4.4 GO:0016095 polyprenol catabolic process(GO:0016095)
2.2 26.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
2.2 13.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
2.2 6.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
2.2 56.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
2.2 10.8 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
2.1 12.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
2.1 21.2 GO:0035878 nail development(GO:0035878)
2.1 14.8 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
2.1 8.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
2.1 25.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
2.1 33.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.1 18.7 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
2.1 8.3 GO:0099640 axo-dendritic protein transport(GO:0099640)
2.1 247.7 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
2.1 12.4 GO:0015853 adenine transport(GO:0015853)
2.0 129.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
2.0 12.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) post-embryonic hemopoiesis(GO:0035166) positive regulation of t-circle formation(GO:1904431)
2.0 6.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
2.0 18.3 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
2.0 10.1 GO:0097338 response to clozapine(GO:0097338)
2.0 8.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.0 7.9 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
2.0 11.8 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.9 9.6 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
1.9 7.7 GO:0071492 cellular response to UV-A(GO:0071492)
1.9 1.9 GO:0009441 glycolate metabolic process(GO:0009441)
1.9 5.7 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
1.9 9.4 GO:0009438 methylglyoxal metabolic process(GO:0009438)
1.9 35.6 GO:0008228 opsonization(GO:0008228)
1.9 5.6 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.8 78.8 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.8 23.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
1.8 7.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
1.8 23.0 GO:0048227 plasma membrane to endosome transport(GO:0048227)
1.8 12.4 GO:2000773 negative regulation of cellular senescence(GO:2000773)
1.8 5.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.7 3.5 GO:1901856 negative regulation of cellular respiration(GO:1901856)
1.7 8.7 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
1.7 19.0 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
1.7 3.4 GO:0030216 epidermal cell differentiation(GO:0009913) keratinocyte differentiation(GO:0030216)
1.7 8.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.7 10.1 GO:0001880 Mullerian duct regression(GO:0001880)
1.7 16.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.7 1.7 GO:0050787 detoxification of mercury ion(GO:0050787)
1.7 20.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
1.7 6.7 GO:0061458 reproductive system development(GO:0061458)
1.7 15.0 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.7 10.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
1.6 16.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.6 12.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.6 28.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.6 9.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.6 4.8 GO:0061198 fungiform papilla formation(GO:0061198)
1.6 7.9 GO:1900063 regulation of peroxisome organization(GO:1900063)
1.6 17.3 GO:0001778 plasma membrane repair(GO:0001778)
1.6 4.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.5 7.7 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
1.5 13.9 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
1.5 6.2 GO:0006408 snRNA export from nucleus(GO:0006408)
1.5 9.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
1.5 3.0 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
1.5 24.0 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.5 56.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
1.5 10.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.5 14.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.5 2.9 GO:0015920 lipopolysaccharide transport(GO:0015920)
1.4 20.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.4 22.5 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
1.4 9.8 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.4 8.2 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
1.4 12.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
1.3 5.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
1.3 11.8 GO:0006983 ER overload response(GO:0006983)
1.3 10.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
1.3 5.1 GO:0007619 courtship behavior(GO:0007619)
1.3 6.4 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
1.3 15.3 GO:0035372 protein localization to microtubule(GO:0035372)
1.2 5.0 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
1.2 5.0 GO:0090527 actin filament reorganization(GO:0090527)
1.2 23.5 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.2 6.2 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
1.2 4.9 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
1.2 7.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.2 16.0 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
1.2 7.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
1.2 2.4 GO:0060467 negative regulation of fertilization(GO:0060467)
1.2 3.7 GO:0051182 coenzyme transport(GO:0051182)
1.2 28.0 GO:0052695 cellular glucuronidation(GO:0052695)
1.2 1.2 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
1.2 3.6 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.2 42.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
1.2 9.6 GO:0090400 stress-induced premature senescence(GO:0090400)
1.2 46.5 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
1.2 2.4 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
1.2 3.5 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
1.2 6.9 GO:0031642 negative regulation of myelination(GO:0031642)
1.2 25.4 GO:0097286 iron ion import(GO:0097286)
1.1 13.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.1 11.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
1.1 3.4 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
1.1 16.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.1 10.0 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
1.1 42.8 GO:0007007 inner mitochondrial membrane organization(GO:0007007) cristae formation(GO:0042407)
1.1 2.2 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
1.1 24.1 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
1.1 8.7 GO:0051096 positive regulation of helicase activity(GO:0051096)
1.1 9.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.1 45.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.1 15.1 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
1.1 17.2 GO:0051683 establishment of Golgi localization(GO:0051683)
1.1 7.4 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.1 27.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.1 9.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
1.0 6.3 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.0 6.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.0 10.4 GO:0006089 lactate metabolic process(GO:0006089)
1.0 3.1 GO:1903751 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
1.0 3.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
1.0 16.4 GO:0035641 locomotory exploration behavior(GO:0035641)
1.0 13.3 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.0 6.1 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917) positive regulation of necrotic cell death(GO:0010940)
1.0 42.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.0 5.0 GO:0071233 cellular response to leucine(GO:0071233)
1.0 2.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.0 21.2 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
1.0 3.8 GO:0030259 lipid glycosylation(GO:0030259)
1.0 8.6 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.9 7.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.9 1.9 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.9 8.3 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
0.9 4.6 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.9 6.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.9 1.8 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.9 40.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.9 11.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.9 8.1 GO:0006552 leucine catabolic process(GO:0006552)
0.9 6.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.9 13.3 GO:0051639 actin filament network formation(GO:0051639)
0.9 5.3 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.9 1.8 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
0.9 3.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.9 5.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.9 11.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.9 2.6 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.9 3.5 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.9 3.5 GO:0060434 bronchus morphogenesis(GO:0060434)
0.9 2.6 GO:2000619 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.9 4.3 GO:1990834 response to odorant(GO:1990834)
0.9 4.3 GO:0010513 regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.9 0.9 GO:0080135 regulation of cellular response to stress(GO:0080135)
0.8 4.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.8 5.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.8 2.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.8 10.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.8 7.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.8 16.5 GO:0006012 galactose metabolic process(GO:0006012)
0.8 1.6 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.8 8.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.8 6.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.8 15.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.8 10.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.8 1.6 GO:0051302 regulation of cell division(GO:0051302)
0.8 1.6 GO:0060926 atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.8 13.9 GO:0090110 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.8 27.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.8 2.4 GO:0042023 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.8 6.3 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.8 5.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.8 0.8 GO:0050818 regulation of blood coagulation(GO:0030193) regulation of coagulation(GO:0050818) regulation of hemostasis(GO:1900046)
0.8 7.8 GO:0043380 regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382)
0.8 2.3 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.8 2.3 GO:0065001 specification of axis polarity(GO:0065001)
0.8 4.5 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.7 37.2 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.7 14.7 GO:0001782 B cell homeostasis(GO:0001782)
0.7 3.6 GO:0035617 stress granule disassembly(GO:0035617)
0.7 5.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.7 8.0 GO:0051601 exocyst localization(GO:0051601)
0.7 10.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.7 17.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.7 2.2 GO:1990523 bone regeneration(GO:1990523)
0.7 3.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.7 0.7 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.7 2.8 GO:0070849 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.7 3.5 GO:0045444 fat cell differentiation(GO:0045444)
0.7 5.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.7 6.9 GO:0002638 negative regulation of immunoglobulin production(GO:0002638)
0.7 6.9 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.7 29.3 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.7 4.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.7 6.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.7 2.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.7 3.4 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.7 1.4 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.7 3.4 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.7 7.4 GO:0051451 myoblast migration(GO:0051451)
0.7 20.5 GO:0014904 myotube cell development(GO:0014904)
0.7 13.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.7 7.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.7 14.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.6 5.8 GO:0051764 actin crosslink formation(GO:0051764)
0.6 3.9 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.6 9.0 GO:0045116 protein neddylation(GO:0045116)
0.6 2.6 GO:0002828 regulation of type 2 immune response(GO:0002828)
0.6 1.9 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.6 1.9 GO:1901253 negative regulation of dendritic cell cytokine production(GO:0002731) regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.6 17.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.6 18.4 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.6 48.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.6 1.3 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.6 3.8 GO:0022417 protein maturation by protein folding(GO:0022417)
0.6 14.5 GO:0051983 regulation of chromosome segregation(GO:0051983)
0.6 3.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.6 6.7 GO:1902224 ketone body metabolic process(GO:1902224)
0.6 10.4 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.6 6.7 GO:0015886 heme transport(GO:0015886)
0.6 1.2 GO:0032730 positive regulation of interleukin-1 alpha production(GO:0032730)
0.6 2.4 GO:1902177 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726) positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.6 4.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6 2.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.6 4.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.6 1.7 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.6 2.3 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.6 4.5 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.6 3.4 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.6 4.4 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.6 7.8 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.6 18.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.6 2.2 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.5 1.6 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.5 1.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.5 12.8 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.5 3.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.5 7.4 GO:0006829 zinc II ion transport(GO:0006829)
0.5 4.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.5 5.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.5 2.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.5 1.6 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.5 3.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.5 3.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.5 5.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.5 4.6 GO:0006183 GTP biosynthetic process(GO:0006183)
0.5 8.6 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.5 11.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.5 3.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.5 3.5 GO:0008218 bioluminescence(GO:0008218)
0.5 17.7 GO:0030224 monocyte differentiation(GO:0030224)
0.5 2.9 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.5 32.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.5 5.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.5 7.3 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.5 8.7 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.5 14.8 GO:0019985 translesion synthesis(GO:0019985)
0.5 1.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.5 2.8 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.5 3.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.5 1.4 GO:0042100 B cell proliferation(GO:0042100)
0.5 2.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.5 14.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.5 4.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.4 1.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.4 1.8 GO:0048496 maintenance of organ identity(GO:0048496)
0.4 13.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.4 0.9 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.4 2.6 GO:0048733 sebaceous gland development(GO:0048733)
0.4 2.6 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.4 5.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.4 3.0 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.4 3.0 GO:0042775 ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.4 20.8 GO:0016925 protein sumoylation(GO:0016925)
0.4 2.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.4 1.7 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.4 0.9 GO:0002027 regulation of heart rate(GO:0002027)
0.4 15.3 GO:0048255 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.4 5.9 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.4 4.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.4 10.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.4 14.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 8.2 GO:0003334 keratinocyte development(GO:0003334)
0.4 2.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.4 20.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.4 1.2 GO:1904814 regulation of establishment of protein localization to telomere(GO:0070203) regulation of protein localization to chromosome, telomeric region(GO:1904814)
0.4 1.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.4 5.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.4 1.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.4 1.5 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.4 91.7 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.4 3.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.4 3.0 GO:0014047 glutamate secretion(GO:0014047)
0.4 6.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.4 2.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.4 1.9 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.4 6.3 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.4 3.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.4 2.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 3.6 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.4 0.7 GO:2000192 negative regulation of icosanoid secretion(GO:0032304) negative regulation of fatty acid transport(GO:2000192)
0.3 8.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.3 8.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.3 1.7 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.3 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.3 7.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.3 0.7 GO:0031960 response to corticosteroid(GO:0031960)
0.3 2.0 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.3 3.3 GO:0001553 luteinization(GO:0001553)
0.3 1.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.3 1.9 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 1.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.3 1.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 1.6 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.3 2.5 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.3 1.9 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 4.6 GO:0018345 protein palmitoylation(GO:0018345)
0.3 5.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.3 3.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 7.6 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.3 0.6 GO:0051036 regulation of endosome size(GO:0051036)
0.3 3.0 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 20.4 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.3 0.9 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.3 13.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.3 3.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.3 0.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.3 2.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.3 1.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 4.1 GO:1902186 regulation of viral release from host cell(GO:1902186)
0.3 2.2 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.3 1.6 GO:0010458 exit from mitosis(GO:0010458)
0.3 1.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 1.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.3 2.3 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.2 1.5 GO:0001881 receptor recycling(GO:0001881)
0.2 1.5 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.2 11.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 5.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 4.8 GO:0010259 multicellular organism aging(GO:0010259)
0.2 1.2 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.2 1.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 3.2 GO:0007567 parturition(GO:0007567)
0.2 0.5 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.2 1.8 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.2 4.0 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.2 1.1 GO:0006574 valine catabolic process(GO:0006574)
0.2 5.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 9.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 2.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 0.4 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)
0.2 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 24.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.2 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 1.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.2 1.6 GO:0006623 protein targeting to vacuole(GO:0006623)
0.2 0.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 1.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 11.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 3.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 1.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 1.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 1.7 GO:0009642 response to light intensity(GO:0009642)
0.2 1.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 1.1 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.2 1.1 GO:0045636 regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636)
0.2 0.6 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.2 0.9 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.2 0.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 1.6 GO:0010815 bradykinin catabolic process(GO:0010815)
0.2 1.2 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.2 1.9 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.2 0.3 GO:0044030 regulation of DNA methylation(GO:0044030)
0.2 1.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 2.7 GO:0045109 intermediate filament organization(GO:0045109)
0.2 2.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.2 0.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.2 5.5 GO:1901998 toxin transport(GO:1901998)
0.2 0.2 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.2 0.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 4.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.2 0.8 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.2 2.2 GO:0046718 viral entry into host cell(GO:0046718)
0.2 2.9 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.2 1.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 1.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.3 GO:0009595 detection of biotic stimulus(GO:0009595)
0.1 0.6 GO:0043129 ceramide transport(GO:0035627) surfactant homeostasis(GO:0043129)
0.1 2.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.6 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992) negative regulation of urine volume(GO:0035811)
0.1 2.0 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.6 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 2.2 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.1 2.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 1.2 GO:0002456 T cell mediated immunity(GO:0002456)
0.1 1.1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 0.6 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 5.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 1.8 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 15.9 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.1 3.7 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 0.4 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.1 0.5 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 5.8 GO:0031100 organ regeneration(GO:0031100)
0.1 1.1 GO:0060438 trachea development(GO:0060438)
0.1 1.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 2.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 3.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 1.4 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 2.7 GO:0046785 microtubule polymerization(GO:0046785)
0.1 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.2 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.6 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.6 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 1.6 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.1 2.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 4.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 0.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 1.5 GO:0007635 chemosensory behavior(GO:0007635)
0.1 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.5 GO:0046037 GMP metabolic process(GO:0046037)
0.1 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 2.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.5 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 0.8 GO:0006825 copper ion transport(GO:0006825)
0.1 1.2 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 1.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 1.8 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.2 GO:0048840 otolith development(GO:0048840)
0.1 0.3 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 1.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.4 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.6 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.4 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.7 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.4 GO:0043586 tongue development(GO:0043586)
0.0 0.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.5 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.5 GO:1904888 cranial skeletal system development(GO:1904888)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.1 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.3 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0001895 retina homeostasis(GO:0001895)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
11.8 47.2 GO:1990423 RZZ complex(GO:1990423)
8.5 25.4 GO:0031262 Ndc80 complex(GO:0031262)
7.2 21.6 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
7.2 35.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
7.1 21.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
6.8 34.0 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
6.5 25.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
6.3 25.2 GO:0000811 GINS complex(GO:0000811)
6.2 18.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
5.9 52.8 GO:0000125 PCAF complex(GO:0000125)
5.6 44.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
5.5 27.7 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
5.3 36.8 GO:0044326 dendritic spine neck(GO:0044326)
5.1 81.3 GO:0031080 nuclear pore outer ring(GO:0031080)
5.0 30.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
4.9 14.7 GO:0005715 late recombination nodule(GO:0005715)
4.8 33.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
4.6 125.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
4.6 23.0 GO:0009368 endopeptidase Clp complex(GO:0009368)
4.5 45.1 GO:0000796 condensin complex(GO:0000796)
4.5 22.4 GO:0043564 Ku70:Ku80 complex(GO:0043564)
4.5 53.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
4.4 17.8 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
4.4 13.2 GO:0001940 male pronucleus(GO:0001940)
4.4 26.2 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
4.3 21.7 GO:0097149 centralspindlin complex(GO:0097149)
4.2 12.7 GO:0005588 collagen type V trimer(GO:0005588)
4.2 29.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
4.2 12.5 GO:0031261 nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
4.0 51.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
4.0 11.9 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
4.0 15.8 GO:0071001 U4/U6 snRNP(GO:0071001)
3.9 11.6 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
3.8 19.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
3.7 41.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
3.6 28.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
3.3 35.8 GO:0005688 U6 snRNP(GO:0005688)
3.2 19.3 GO:0070545 PeBoW complex(GO:0070545)
3.2 25.4 GO:0032133 chromosome passenger complex(GO:0032133)
3.2 28.4 GO:0070652 HAUS complex(GO:0070652)
3.1 53.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
3.1 24.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
3.0 15.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
3.0 9.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
3.0 8.9 GO:0097447 dendritic tree(GO:0097447)
2.9 8.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
2.9 11.7 GO:0055087 Ski complex(GO:0055087)
2.9 34.8 GO:0031595 nuclear proteasome complex(GO:0031595)
2.9 51.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
2.9 45.8 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
2.8 50.3 GO:0034709 methylosome(GO:0034709)
2.7 24.2 GO:0005827 polar microtubule(GO:0005827)
2.6 15.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
2.6 10.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
2.6 18.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
2.6 12.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
2.5 17.6 GO:0070852 cell body fiber(GO:0070852)
2.5 7.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
2.5 22.1 GO:0072546 ER membrane protein complex(GO:0072546)
2.4 14.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
2.4 28.4 GO:0005838 proteasome regulatory particle(GO:0005838)
2.4 14.2 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
2.3 88.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
2.2 8.7 GO:0044611 nuclear pore inner ring(GO:0044611)
2.2 39.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
2.2 54.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
2.2 4.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
2.1 21.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
2.1 6.4 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
2.1 10.7 GO:0035370 UBC13-UEV1A complex(GO:0035370)
2.1 6.4 GO:0034657 GID complex(GO:0034657)
2.1 10.6 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
2.1 14.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
2.0 38.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
2.0 27.9 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
2.0 13.8 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
1.9 7.8 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.9 11.5 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.9 9.5 GO:0070847 core mediator complex(GO:0070847)
1.9 5.7 GO:0071020 post-spliceosomal complex(GO:0071020)
1.9 7.5 GO:0070985 TFIIK complex(GO:0070985)
1.9 18.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.8 18.5 GO:0070187 telosome(GO:0070187)
1.8 35.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.8 19.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.7 5.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
1.7 8.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.7 10.2 GO:0001740 Barr body(GO:0001740)
1.7 79.6 GO:0008180 COP9 signalosome(GO:0008180)
1.7 13.2 GO:0034719 SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
1.6 100.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.6 16.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.6 8.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
1.6 12.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.6 4.7 GO:0002079 inner acrosomal membrane(GO:0002079)
1.6 15.7 GO:0030126 COPI vesicle coat(GO:0030126)
1.5 24.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.5 3.0 GO:0035869 ciliary transition zone(GO:0035869)
1.5 10.5 GO:0061617 MICOS complex(GO:0061617)
1.5 5.9 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
1.5 7.4 GO:0005839 proteasome core complex(GO:0005839)
1.4 5.8 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
1.4 5.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.4 5.7 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
1.4 9.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.4 17.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
1.3 43.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.3 13.0 GO:0000243 commitment complex(GO:0000243)
1.3 9.0 GO:0031415 NatA complex(GO:0031415)
1.3 6.4 GO:0032449 CBM complex(GO:0032449)
1.3 8.8 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
1.2 18.7 GO:0005869 dynactin complex(GO:0005869)
1.2 3.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.2 8.5 GO:0016272 prefoldin complex(GO:0016272)
1.2 4.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.2 9.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.2 7.0 GO:0031597 cytosolic proteasome complex(GO:0031597)
1.1 22.9 GO:0032591 dendritic spine membrane(GO:0032591)
1.1 5.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.1 4.6 GO:0005846 nuclear cap binding complex(GO:0005846)
1.1 4.5 GO:0032044 DSIF complex(GO:0032044)
1.1 10.1 GO:0071439 clathrin complex(GO:0071439)
1.1 31.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.1 16.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
1.1 8.8 GO:0042382 paraspeckles(GO:0042382)
1.1 6.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.1 27.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.0 25.2 GO:0000930 gamma-tubulin complex(GO:0000930)
1.0 4.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
1.0 22.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.0 4.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.0 4.0 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
1.0 4.0 GO:0030891 VCB complex(GO:0030891)
1.0 2.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.0 13.4 GO:0098803 respiratory chain complex(GO:0098803)
1.0 11.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.9 11.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.9 16.8 GO:0005685 U1 snRNP(GO:0005685)
0.9 26.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.9 1.8 GO:0002139 stereocilia coupling link(GO:0002139)
0.9 3.5 GO:0031085 BLOC-3 complex(GO:0031085)
0.9 2.6 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.9 2.6 GO:1902636 kinociliary basal body(GO:1902636)
0.9 4.4 GO:0071986 Ragulator complex(GO:0071986)
0.9 32.2 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.9 27.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.9 12.1 GO:0031209 SCAR complex(GO:0031209)
0.9 14.7 GO:0032433 filopodium tip(GO:0032433)
0.9 9.5 GO:0051233 spindle midzone(GO:0051233)
0.9 9.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.8 10.1 GO:0071141 SMAD protein complex(GO:0071141)
0.8 5.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.8 16.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.8 6.7 GO:0005675 holo TFIIH complex(GO:0005675)
0.8 7.5 GO:0097470 ribbon synapse(GO:0097470)
0.8 53.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.8 5.7 GO:0000974 Prp19 complex(GO:0000974)
0.8 15.9 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.8 15.7 GO:0042588 zymogen granule(GO:0042588)
0.8 23.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.8 6.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.8 4.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.8 3.8 GO:1990425 ryanodine receptor complex(GO:1990425)
0.7 9.5 GO:0000815 ESCRT III complex(GO:0000815)
0.7 34.8 GO:0045171 intercellular bridge(GO:0045171)
0.7 9.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.7 2.1 GO:0002080 acrosomal membrane(GO:0002080)
0.7 8.3 GO:0042555 MCM complex(GO:0042555)
0.7 11.8 GO:0031932 TORC2 complex(GO:0031932)
0.7 6.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.7 18.8 GO:0031143 pseudopodium(GO:0031143)
0.7 4.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.7 12.0 GO:0097342 ripoptosome(GO:0097342)
0.6 6.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.6 27.6 GO:0043034 costamere(GO:0043034)
0.6 8.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.6 5.0 GO:0070938 contractile ring(GO:0070938)
0.6 7.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.6 3.6 GO:0035253 ciliary rootlet(GO:0035253)
0.6 76.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.6 3.0 GO:0000346 transcription export complex(GO:0000346)
0.6 6.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.6 3.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.6 10.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.6 66.0 GO:0000781 chromosome, telomeric region(GO:0000781)
0.6 41.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.6 3.4 GO:0071438 invadopodium membrane(GO:0071438)
0.6 17.9 GO:0016592 mediator complex(GO:0016592)
0.6 5.5 GO:0043219 lateral loop(GO:0043219)
0.5 11.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 42.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5 2.6 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.5 29.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.5 7.5 GO:0000776 kinetochore(GO:0000776)
0.5 5.9 GO:0017119 Golgi transport complex(GO:0017119)
0.5 5.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.5 12.5 GO:1902555 endoribonuclease complex(GO:1902555)
0.5 0.5 GO:0032009 early phagosome(GO:0032009)
0.5 5.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 1.8 GO:0019867 outer membrane(GO:0019867)
0.4 7.9 GO:0044297 cell body(GO:0044297)
0.4 1.7 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.4 3.9 GO:0044292 dendrite terminus(GO:0044292)
0.4 19.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 3.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 1.6 GO:0035838 growing cell tip(GO:0035838)
0.4 3.6 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.4 1.2 GO:0031213 RSF complex(GO:0031213)
0.4 6.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 1.5 GO:1990031 pinceau fiber(GO:1990031)
0.4 3.4 GO:0001533 cornified envelope(GO:0001533)
0.4 28.5 GO:0031970 organelle envelope lumen(GO:0031970)
0.4 4.9 GO:0044754 autolysosome(GO:0044754)
0.4 3.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.4 1.4 GO:0032389 MutLalpha complex(GO:0032389)
0.4 4.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 5.3 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.3 2.7 GO:0001772 immunological synapse(GO:0001772)
0.3 1.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 32.9 GO:0005681 spliceosomal complex(GO:0005681)
0.3 84.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.3 7.6 GO:0099738 cell cortex region(GO:0099738)
0.3 2.8 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.3 1.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.3 1.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 12.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 5.9 GO:0005876 spindle microtubule(GO:0005876)
0.3 58.8 GO:0031965 nuclear membrane(GO:0031965)
0.3 24.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.3 8.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 30.4 GO:0032587 ruffle membrane(GO:0032587)
0.3 12.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 232.9 GO:0005730 nucleolus(GO:0005730)
0.3 22.9 GO:0005884 actin filament(GO:0005884)
0.3 9.5 GO:0005771 multivesicular body(GO:0005771)
0.3 1.8 GO:0005955 calcineurin complex(GO:0005955)
0.2 10.6 GO:0036379 myofilament(GO:0036379)
0.2 1.7 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 1.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 16.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 6.3 GO:0000421 autophagosome membrane(GO:0000421)
0.2 3.5 GO:0016580 Sin3 complex(GO:0016580)
0.2 24.1 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 15.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 5.2 GO:0097228 sperm principal piece(GO:0097228)
0.2 3.0 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 2.9 GO:0071564 npBAF complex(GO:0071564)
0.2 3.3 GO:0031105 septin complex(GO:0031105)
0.2 7.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 1.9 GO:0031094 platelet dense tubular network(GO:0031094)
0.2 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.7 GO:0032280 symmetric synapse(GO:0032280)
0.2 8.0 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 11.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 0.9 GO:0033503 HULC complex(GO:0033503)
0.2 1.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.2 0.7 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.2 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 6.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.3 GO:0000145 exocyst(GO:0000145)
0.2 11.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.2 GO:0030018 Z disc(GO:0030018) I band(GO:0031674)
0.1 0.3 GO:0033646 host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.1 14.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 3.5 GO:0031430 M band(GO:0031430)
0.1 1.7 GO:0032982 myosin filament(GO:0032982)
0.1 4.6 GO:0045095 keratin filament(GO:0045095)
0.1 10.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 3.1 GO:0000502 proteasome complex(GO:0000502)
0.1 5.9 GO:0031526 brush border membrane(GO:0031526)
0.1 1.4 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.0 GO:0043194 axon initial segment(GO:0043194)
0.1 1.4 GO:0097546 ciliary base(GO:0097546)
0.1 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 3.1 GO:0030427 site of polarized growth(GO:0030427)
0.1 2.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 10.1 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529)
0.1 0.9 GO:0030990 intraciliary transport particle(GO:0030990)
0.1 72.5 GO:0005739 mitochondrion(GO:0005739)
0.1 2.3 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 2.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 1.9 GO:0031975 organelle envelope(GO:0031967) envelope(GO:0031975)
0.0 0.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 6.1 GO:0016604 nuclear body(GO:0016604)
0.0 20.2 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 42.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
10.5 31.4 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
9.5 28.6 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
9.0 26.9 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
8.8 26.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
8.7 26.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
8.5 8.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
7.6 30.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
7.2 28.8 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
7.1 35.7 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
7.1 99.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
6.4 19.3 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
6.1 24.2 GO:0031208 POZ domain binding(GO:0031208)
5.9 35.6 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
5.6 16.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
5.5 16.5 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
5.3 26.7 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
5.1 15.4 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
5.1 35.8 GO:0004849 uridine kinase activity(GO:0004849)
5.0 10.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
5.0 44.6 GO:0008312 7S RNA binding(GO:0008312)
4.7 18.7 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
4.7 14.0 GO:0017130 poly(C) RNA binding(GO:0017130)
4.4 26.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
4.4 13.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
4.3 30.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
4.3 25.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
4.3 12.8 GO:0070538 oleic acid binding(GO:0070538)
4.2 20.9 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
4.1 12.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
4.1 28.8 GO:0002151 G-quadruplex RNA binding(GO:0002151)
3.9 11.6 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
3.8 38.0 GO:0042731 PH domain binding(GO:0042731)
3.7 22.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
3.6 10.9 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
3.6 29.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
3.6 10.8 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
3.4 10.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
3.4 23.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
3.3 33.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
3.3 16.6 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
3.3 13.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
3.3 98.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
3.2 19.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
3.2 44.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
3.0 21.3 GO:0030621 U4 snRNA binding(GO:0030621)
3.0 17.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.9 5.8 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
2.8 25.4 GO:0035174 histone serine kinase activity(GO:0035174)
2.8 27.7 GO:1990446 U1 snRNP binding(GO:1990446)
2.8 19.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
2.8 8.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
2.7 8.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
2.7 10.7 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
2.6 5.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
2.6 10.4 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.5 42.1 GO:0008494 translation activator activity(GO:0008494)
2.4 9.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
2.4 9.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
2.4 37.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
2.3 7.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
2.3 13.9 GO:0042296 ISG15 transferase activity(GO:0042296)
2.3 6.9 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) pyrimidine ribonucleotide binding(GO:0032557)
2.3 6.8 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
2.2 22.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.2 8.9 GO:0043515 kinetochore binding(GO:0043515)
2.2 13.3 GO:1903135 cupric ion binding(GO:1903135)
2.2 19.8 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
2.2 13.1 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
2.2 17.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
2.2 88.7 GO:0004532 exoribonuclease activity(GO:0004532)
2.1 23.0 GO:0046790 virion binding(GO:0046790)
2.1 10.4 GO:0000405 bubble DNA binding(GO:0000405)
2.1 6.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
2.0 8.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
2.0 105.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
2.0 12.1 GO:0019238 cyclohydrolase activity(GO:0019238)
2.0 22.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
2.0 6.0 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
2.0 21.6 GO:0033038 bitter taste receptor activity(GO:0033038)
1.9 7.8 GO:0004312 fatty acid synthase activity(GO:0004312)
1.9 7.8 GO:0000104 succinate dehydrogenase activity(GO:0000104)
1.9 19.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
1.9 13.2 GO:0008266 poly(U) RNA binding(GO:0008266)
1.9 5.7 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
1.9 71.4 GO:0017025 TBP-class protein binding(GO:0017025)
1.9 46.6 GO:0070717 poly-purine tract binding(GO:0070717)
1.8 9.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.8 14.7 GO:0032137 guanine/thymine mispair binding(GO:0032137)
1.8 14.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.8 12.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.7 5.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
1.7 7.0 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
1.7 10.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.7 5.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
1.7 8.5 GO:0070404 NADH binding(GO:0070404)
1.7 5.1 GO:0033149 FFAT motif binding(GO:0033149)
1.7 23.5 GO:0042809 vitamin D receptor binding(GO:0042809)
1.7 11.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
1.7 53.3 GO:0008308 voltage-gated anion channel activity(GO:0008308)
1.6 8.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
1.6 21.2 GO:0038132 neuregulin binding(GO:0038132)
1.6 44.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.6 13.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.6 48.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
1.6 8.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
1.6 17.8 GO:0031386 protein tag(GO:0031386)
1.6 4.8 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.6 25.8 GO:0004526 ribonuclease P activity(GO:0004526)
1.6 37.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
1.6 6.4 GO:0036033 mediator complex binding(GO:0036033)
1.6 6.4 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
1.6 7.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.6 12.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.6 18.9 GO:0035173 histone kinase activity(GO:0035173)
1.6 45.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.5 4.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.5 6.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.5 14.9 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
1.5 10.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791) protein-disulfide reductase activity(GO:0047134)
1.5 19.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
1.5 60.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.5 14.7 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.5 27.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.4 5.8 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
1.4 27.4 GO:0000339 RNA cap binding(GO:0000339)
1.4 4.3 GO:0030984 kininogen binding(GO:0030984)
1.4 4.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
1.4 43.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.4 47.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.4 9.5 GO:1990226 histone methyltransferase binding(GO:1990226)
1.3 6.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.3 33.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.3 12.0 GO:0035877 death effector domain binding(GO:0035877)
1.3 12.0 GO:0032051 clathrin light chain binding(GO:0032051)
1.3 14.6 GO:0015266 protein channel activity(GO:0015266)
1.3 4.0 GO:0048030 disaccharide binding(GO:0048030)
1.3 6.6 GO:0004771 sterol esterase activity(GO:0004771)
1.3 26.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.3 10.4 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
1.3 9.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.3 11.4 GO:0000182 rDNA binding(GO:0000182)
1.3 6.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
1.2 17.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.2 66.9 GO:0003743 translation initiation factor activity(GO:0003743)
1.2 7.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.2 7.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.2 6.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.2 3.7 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
1.2 13.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.2 11.7 GO:0015232 heme transporter activity(GO:0015232)
1.2 24.3 GO:0070628 proteasome binding(GO:0070628)
1.1 11.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.1 7.9 GO:0050733 RS domain binding(GO:0050733)
1.1 30.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.1 4.5 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
1.1 43.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.1 4.4 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
1.1 15.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.1 13.1 GO:0017049 GTP-Rho binding(GO:0017049)
1.1 14.1 GO:0050786 RAGE receptor binding(GO:0050786)
1.1 12.9 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.1 2.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
1.1 31.7 GO:0070840 dynein complex binding(GO:0070840)
1.1 3.2 GO:0004301 epoxide hydrolase activity(GO:0004301) ether hydrolase activity(GO:0016803)
1.1 25.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.1 5.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.1 22.1 GO:0001055 RNA polymerase II activity(GO:0001055)
1.0 8.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.0 25.8 GO:0031489 myosin V binding(GO:0031489)
1.0 3.0 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
1.0 10.9 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
1.0 6.9 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
1.0 3.9 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.0 38.2 GO:0048487 beta-tubulin binding(GO:0048487)
1.0 4.9 GO:0070728 leucine binding(GO:0070728)
1.0 8.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
1.0 5.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.0 44.1 GO:0000049 tRNA binding(GO:0000049)
0.9 7.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.9 3.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.9 19.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.9 21.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.9 4.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.9 11.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.9 15.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.9 8.1 GO:1901612 cardiolipin binding(GO:1901612)
0.9 23.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.9 10.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.9 182.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.9 20.5 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.8 5.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.8 27.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.8 12.2 GO:0008432 JUN kinase binding(GO:0008432)
0.8 30.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.8 15.9 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.8 3.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.8 25.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.8 13.5 GO:0035497 cAMP response element binding(GO:0035497)
0.8 6.0 GO:0043559 insulin binding(GO:0043559)
0.7 2.9 GO:0035276 ethanol binding(GO:0035276)
0.7 2.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.7 2.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.7 42.0 GO:0035064 methylated histone binding(GO:0035064)
0.7 10.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.7 8.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.7 5.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.7 10.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.7 4.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.7 26.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.7 5.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.7 3.4 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.7 5.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.7 5.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.7 8.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.7 17.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.6 1.9 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.6 1.9 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.6 12.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.6 8.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.6 11.1 GO:0004697 protein kinase C activity(GO:0004697)
0.6 3.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.6 8.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.6 6.7 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.6 32.8 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.6 9.6 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.6 4.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.6 5.8 GO:0030957 Tat protein binding(GO:0030957)
0.6 11.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.6 14.1 GO:0070064 proline-rich region binding(GO:0070064)
0.6 11.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.6 9.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.6 12.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.6 2.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.5 15.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 1.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.5 4.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.5 14.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.5 3.7 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.5 1.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 1.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.5 28.1 GO:0019003 GDP binding(GO:0019003)
0.5 1.0 GO:0016778 diphosphotransferase activity(GO:0016778)
0.5 3.5 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.5 2.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.5 4.0 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.5 3.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.5 9.2 GO:0097602 cullin family protein binding(GO:0097602)
0.5 3.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.5 32.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.5 7.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 1.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.5 3.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.5 6.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.5 18.0 GO:0019894 kinesin binding(GO:0019894)
0.5 9.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.5 6.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 8.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 6.7 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.4 1.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 2.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.4 2.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.4 4.2 GO:0051434 BH3 domain binding(GO:0051434)
0.4 26.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 3.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.4 9.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.4 2.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.4 5.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 1.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.4 1.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 2.4 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.4 10.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 4.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.4 2.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.4 11.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 3.7 GO:0034594 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.4 20.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.4 21.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.4 0.7 GO:1990763 arrestin family protein binding(GO:1990763)
0.4 9.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 3.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 7.6 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.3 1.0 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.3 5.0 GO:0017069 snRNA binding(GO:0017069)
0.3 2.3 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.3 2.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 2.9 GO:0008158 hedgehog receptor activity(GO:0008158)
0.3 3.9 GO:0043274 phospholipase binding(GO:0043274)
0.3 2.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 4.9 GO:0030515 snoRNA binding(GO:0030515)
0.3 2.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 1.9 GO:0017091 AU-rich element binding(GO:0017091)
0.3 7.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.3 26.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 4.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.3 0.9 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.3 3.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 11.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.3 0.6 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.3 1.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 5.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 4.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 7.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.3 3.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3 3.3 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.3 0.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 4.1 GO:0008198 ferrous iron binding(GO:0008198)
0.3 9.5 GO:0050681 androgen receptor binding(GO:0050681)
0.3 6.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.3 2.4 GO:0032190 acrosin binding(GO:0032190)
0.3 6.2 GO:0043022 ribosome binding(GO:0043022)
0.3 1.8 GO:0017022 myosin binding(GO:0017022)
0.3 1.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 84.4 GO:0045296 cadherin binding(GO:0045296)
0.2 6.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 13.8 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.2 0.7 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2 18.8 GO:0008565 protein transporter activity(GO:0008565)
0.2 1.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 2.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 1.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 1.6 GO:0043495 protein anchor(GO:0043495)
0.2 19.3 GO:0042393 histone binding(GO:0042393)
0.2 3.2 GO:0070410 co-SMAD binding(GO:0070410)
0.2 5.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 3.0 GO:0008301 DNA binding, bending(GO:0008301)
0.2 2.4 GO:0005112 Notch binding(GO:0005112)
0.2 1.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 10.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 3.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 1.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 2.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.3 GO:0043295 glutathione binding(GO:0043295)
0.2 0.6 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338) GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2 0.6 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.2 3.0 GO:0002162 dystroglycan binding(GO:0002162)
0.2 2.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 0.9 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.2 1.4 GO:0003680 AT DNA binding(GO:0003680)
0.2 1.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 10.4 GO:0030165 PDZ domain binding(GO:0030165)
0.2 2.4 GO:0050811 GABA receptor binding(GO:0050811)
0.2 30.5 GO:0008017 microtubule binding(GO:0008017)
0.2 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 0.7 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.2 0.2 GO:0050664 superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.2 6.0 GO:0070888 E-box binding(GO:0070888)
0.2 4.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 4.4 GO:0032947 protein complex scaffold(GO:0032947)
0.2 6.2 GO:0097110 scaffold protein binding(GO:0097110)
0.2 4.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 3.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.1 8.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 3.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 8.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.7 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 18.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.6 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 2.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.3 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 3.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 6.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 1.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 17.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 1.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 11.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 3.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 13.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.5 GO:0019905 syntaxin binding(GO:0019905)
0.1 3.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 1.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 2.2 GO:0046332 SMAD binding(GO:0046332)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.8 GO:0050699 WW domain binding(GO:0050699)
0.1 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0005537 mannose binding(GO:0005537)
0.1 0.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 20.2 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 2.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.1 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.5 GO:0003682 chromatin binding(GO:0003682)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 41.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.4 57.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
1.4 169.3 PID E2F PATHWAY E2F transcription factor network
1.4 6.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
1.3 35.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.3 78.5 PID PLK1 PATHWAY PLK1 signaling events
1.2 50.0 PID MYC PATHWAY C-MYC pathway
1.0 56.5 PID AURORA B PATHWAY Aurora B signaling
1.0 72.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.9 24.4 PID ATR PATHWAY ATR signaling pathway
0.9 47.5 PID IL3 PATHWAY IL3-mediated signaling events
0.9 21.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.8 10.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.8 23.8 PID IGF1 PATHWAY IGF1 pathway
0.8 8.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.8 52.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.8 22.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.8 22.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.7 13.9 PID ALK2 PATHWAY ALK2 signaling events
0.7 27.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.7 16.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.7 20.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.7 50.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.6 46.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.6 14.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.6 56.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.6 50.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.6 13.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.6 4.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.6 98.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.5 4.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.5 14.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.5 16.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.5 11.0 PID ATM PATHWAY ATM pathway
0.5 19.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.5 10.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.4 7.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 9.1 PID IL1 PATHWAY IL1-mediated signaling events
0.4 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 6.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.4 17.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.4 23.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.4 17.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.4 9.6 PID TNF PATHWAY TNF receptor signaling pathway
0.4 1.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 12.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 22.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.4 9.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.3 9.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 23.6 PID CMYB PATHWAY C-MYB transcription factor network
0.3 6.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 1.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.3 1.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 10.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 3.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 11.0 PID NOTCH PATHWAY Notch signaling pathway
0.2 12.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 7.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 2.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 12.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 6.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 4.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 5.5 PID CDC42 PATHWAY CDC42 signaling events
0.2 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 1.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 3.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 6.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 2.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.1 PID RHOA PATHWAY RhoA signaling pathway
0.1 0.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 52.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
3.7 71.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
3.5 59.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
3.4 30.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
3.2 56.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
3.1 47.1 REACTOME POL SWITCHING Genes involved in Polymerase switching
3.1 61.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
2.7 282.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.6 12.8 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
2.5 35.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
2.5 37.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
2.5 49.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
2.3 86.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
2.3 129.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
2.1 2.1 REACTOME LAGGING STRAND SYNTHESIS Genes involved in Lagging Strand Synthesis
2.1 76.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
2.1 65.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
2.1 29.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
2.1 43.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
2.0 54.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.9 163.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.9 80.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
1.9 53.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
1.8 34.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.8 14.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
1.7 27.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.7 35.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
1.6 36.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.6 21.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.6 50.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.6 15.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
1.5 114.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
1.5 39.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.5 25.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
1.4 15.8 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
1.3 8.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
1.3 29.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
1.2 31.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
1.2 17.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.2 12.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.2 23.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.2 18.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
1.2 37.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.2 36.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
1.1 13.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.1 18.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.1 36.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
1.1 13.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
1.1 22.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
1.1 20.0 REACTOME KINESINS Genes involved in Kinesins
1.0 24.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.0 71.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
1.0 9.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
1.0 34.6 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
1.0 15.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.9 8.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.9 17.7 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.9 16.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.9 4.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.9 66.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.9 53.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.8 27.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.8 37.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.7 19.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.7 6.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.7 7.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.7 18.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.7 13.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.7 64.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.7 11.3 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.7 5.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.7 15.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.6 6.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.6 13.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 10.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.6 77.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.5 7.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.5 12.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.4 6.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.4 23.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.4 10.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.4 7.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.4 9.6 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.4 13.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.4 63.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.4 5.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.4 10.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.4 3.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 5.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.3 2.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 3.0 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.3 8.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.3 15.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 5.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 1.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.3 7.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 1.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.3 11.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.3 4.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 7.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 4.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 3.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 1.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 2.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 2.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 4.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 1.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 11.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 4.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 7.8 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 15.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 3.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 6.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 11.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 4.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 2.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 9.3 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 2.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.0 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.1 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events