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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CCUUCAU

Z-value: 0.89

Motif logo

logo of

miRNA associated with seed CCUUCAU

NamemiRBASE accession
hsa-miR-205-5p
MIMAT0000266

Activity profile of CCUUCAU motif

Sorted Z-values of CCUUCAU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_182992545 11.00 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr20_+_11871371 10.10 ENST00000254977.3
BTBD3
BTB (POZ) domain containing 3
chr12_+_56473628 8.08 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr5_+_167718604 7.94 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr7_-_10979750 7.76 ENST00000339600.5
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr6_+_114178512 7.53 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_-_63988846 7.43 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr11_-_115375107 6.87 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr2_-_161350305 6.60 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr20_-_48330377 6.14 ENST00000371711.4
B4GALT5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chrX_-_20284958 5.76 ENST00000379565.3
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr3_+_150321068 5.51 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
SELT
Selenoprotein T
chr2_-_64881018 5.17 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr17_+_57697216 4.96 ENST00000393043.1
ENST00000269122.3
CLTC
clathrin, heavy chain (Hc)
chr2_-_200322723 4.59 ENST00000417098.1
SATB2
SATB homeobox 2
chr1_+_201924619 4.55 ENST00000367287.4
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr6_-_31830655 4.27 ENST00000375631.4
NEU1
sialidase 1 (lysosomal sialidase)
chr17_-_46178527 4.24 ENST00000393408.3
CBX1
chromobox homolog 1
chr1_-_224033596 3.98 ENST00000391878.2
ENST00000343537.7
TP53BP2
tumor protein p53 binding protein, 2
chr11_+_9406169 3.90 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr2_-_175869936 3.86 ENST00000409900.3
CHN1
chimerin 1
chr9_+_36572851 3.79 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr6_-_116381918 3.73 ENST00000606080.1
FRK
fyn-related kinase
chr9_-_14314066 3.62 ENST00000397575.3
NFIB
nuclear factor I/B
chr16_-_87525651 3.53 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr12_+_104682496 3.37 ENST00000378070.4
TXNRD1
thioredoxin reductase 1
chr10_-_98346801 3.09 ENST00000371142.4
TM9SF3
transmembrane 9 superfamily member 3
chr1_+_26606608 2.90 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chrX_+_46771711 2.86 ENST00000424392.1
ENST00000397189.1
PHF16
jade family PHD finger 3
chr4_+_184020398 2.78 ENST00000403733.3
ENST00000378925.3
WWC2
WW and C2 domain containing 2
chr16_+_4674814 2.55 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr5_-_137878887 2.41 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr5_-_1524015 2.36 ENST00000283415.3
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr17_-_47492236 2.35 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB
prohibitin
chr1_-_120612240 2.35 ENST00000256646.2
NOTCH2
notch 2
chr1_-_155211017 2.18 ENST00000536770.1
ENST00000368373.3
GBA
glucosidase, beta, acid
chr17_+_44668035 2.16 ENST00000398238.4
ENST00000225282.8
NSF
N-ethylmaleimide-sensitive factor
chr1_+_214776516 2.16 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr3_+_141106643 2.05 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr5_-_73937244 1.98 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr7_+_128379346 1.89 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr11_+_71935797 1.87 ENST00000298229.2
ENST00000541756.1
INPPL1
inositol polyphosphate phosphatase-like 1
chr17_+_15902694 1.84 ENST00000261647.5
ENST00000486880.2
TTC19
tetratricopeptide repeat domain 19
chr10_+_28966271 1.80 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr6_+_43737939 1.79 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr3_+_179370517 1.77 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr17_+_40118759 1.74 ENST00000393892.3
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr13_+_100153665 1.68 ENST00000376387.4
TM9SF2
transmembrane 9 superfamily member 2
chr12_-_93835665 1.63 ENST00000552442.1
ENST00000550657.1
UBE2N
ubiquitin-conjugating enzyme E2N
chr12_+_22778009 1.63 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chr11_+_101981169 1.61 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1
Yes-associated protein 1
chr2_+_204192942 1.51 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr3_+_61547585 1.46 ENST00000295874.10
ENST00000474889.1
PTPRG
protein tyrosine phosphatase, receptor type, G
chr4_+_77870856 1.46 ENST00000264893.6
ENST00000502584.1
ENST00000510641.1
SEPT11
septin 11
chr6_-_52441713 1.45 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr10_+_60272814 1.45 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr4_-_40631859 1.45 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr18_-_29264669 1.41 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr2_-_85788605 1.41 ENST00000233838.4
GGCX
gamma-glutamyl carboxylase
chr5_+_115420688 1.36 ENST00000274458.4
COMMD10
COMM domain containing 10
chr12_+_96588143 1.34 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr4_-_99851766 1.30 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr1_+_93913713 1.28 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr9_+_33025209 1.25 ENST00000330899.4
ENST00000544625.1
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr4_+_146402925 1.20 ENST00000302085.4
SMAD1
SMAD family member 1
chr20_-_1447467 1.17 ENST00000353088.2
ENST00000350991.4
NSFL1C
NSFL1 (p97) cofactor (p47)
chr3_-_52090461 1.15 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr17_+_45608430 1.14 ENST00000322157.4
NPEPPS
aminopeptidase puromycin sensitive
chr2_-_172017343 1.13 ENST00000431350.2
ENST00000360843.3
TLK1
tousled-like kinase 1
chrX_+_56590002 1.11 ENST00000338222.5
UBQLN2
ubiquilin 2
chr13_-_31038370 1.10 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr14_-_68141535 1.08 ENST00000554659.1
VTI1B
vesicle transport through interaction with t-SNAREs 1B
chr16_-_10674528 1.08 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr17_+_2496971 1.08 ENST00000397195.5
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr6_-_159239257 1.02 ENST00000337147.7
ENST00000392177.4
EZR
ezrin
chr4_+_75230853 1.02 ENST00000244869.2
EREG
epiregulin
chr8_-_37756972 1.01 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr6_+_43044003 0.99 ENST00000230419.4
ENST00000476760.1
ENST00000471863.1
ENST00000349241.2
ENST00000352931.2
ENST00000345201.2
PTK7
protein tyrosine kinase 7
chr13_+_50656307 0.98 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr17_-_4269768 0.97 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr14_-_70883708 0.87 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr11_-_85780086 0.86 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr1_+_10271674 0.85 ENST00000377086.1
KIF1B
kinesin family member 1B
chr16_+_69599861 0.79 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr6_+_88182643 0.78 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
SLC35A1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr5_-_148930960 0.78 ENST00000261798.5
ENST00000377843.2
CSNK1A1
casein kinase 1, alpha 1
chr14_+_19553365 0.78 ENST00000409832.3
POTEG
POTE ankyrin domain family, member G
chr16_+_86544113 0.77 ENST00000262426.4
FOXF1
forkhead box F1
chr2_-_97535708 0.77 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr5_-_77844974 0.75 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr2_+_181845298 0.75 ENST00000410062.4
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr1_+_110453203 0.66 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr12_-_63328817 0.66 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr21_-_15755446 0.66 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr7_-_41742697 0.65 ENST00000242208.4
INHBA
inhibin, beta A
chr14_+_90863327 0.65 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr2_-_11484710 0.62 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr2_-_131267239 0.61 ENST00000451531.2
POTEI
POTE ankyrin domain family, member I
chr1_-_201438282 0.60 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr9_-_123964114 0.56 ENST00000373840.4
RAB14
RAB14, member RAS oncogene family
chr8_-_116681221 0.56 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr14_-_20020272 0.52 ENST00000551509.1
POTEM
POTE ankyrin domain family, member M
chr15_+_39873268 0.49 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr20_-_32274179 0.44 ENST00000343380.5
E2F1
E2F transcription factor 1
chr4_-_185747188 0.44 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
ACSL1
acyl-CoA synthetase long-chain family member 1
chr16_+_67880574 0.44 ENST00000219169.4
NUTF2
nuclear transport factor 2
chr17_+_61678225 0.43 ENST00000258975.6
TACO1
translational activator of mitochondrially encoded cytochrome c oxidase I
chr16_-_71843047 0.42 ENST00000299980.4
ENST00000393512.3
AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr17_-_37607497 0.42 ENST00000394287.3
ENST00000300651.6
MED1
mediator complex subunit 1
chr1_+_27022485 0.40 ENST00000324856.7
ARID1A
AT rich interactive domain 1A (SWI-like)
chr3_-_125094093 0.40 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148
zinc finger protein 148
chr2_+_109335929 0.39 ENST00000283195.6
RANBP2
RAN binding protein 2
chr1_-_38325256 0.38 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr10_+_97803151 0.35 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ
cyclin J
chr1_-_169455169 0.35 ENST00000367804.4
ENST00000236137.5
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr12_+_67663056 0.34 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr12_-_115121962 0.33 ENST00000349155.2
TBX3
T-box 3
chr18_-_23670546 0.33 ENST00000542743.1
ENST00000545952.1
ENST00000539849.1
ENST00000415083.2
SS18
synovial sarcoma translocation, chromosome 18
chr2_+_208394616 0.32 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr17_-_62502639 0.32 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr8_-_68255912 0.30 ENST00000262215.3
ENST00000519436.1
ARFGEF1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr13_-_108518986 0.26 ENST00000375915.2
FAM155A
family with sequence similarity 155, member A
chrX_-_30595959 0.25 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr10_-_121356007 0.25 ENST00000369093.2
ENST00000436547.2
TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr3_+_170136642 0.25 ENST00000064724.3
ENST00000486975.1
CLDN11
claudin 11
chr15_-_49338748 0.24 ENST00000559471.1
SECISBP2L
SECIS binding protein 2-like
chr1_-_185286461 0.18 ENST00000367498.3
IVNS1ABP
influenza virus NS1A binding protein
chrX_+_7137475 0.18 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr2_+_176987088 0.18 ENST00000249499.6
HOXD9
homeobox D9
chr1_+_145507587 0.16 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr3_-_122233723 0.13 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr10_+_70091812 0.13 ENST00000265866.7
HNRNPH3
heterogeneous nuclear ribonucleoprotein H3 (2H9)
chr1_-_24306798 0.12 ENST00000374452.5
ENST00000492112.2
ENST00000343255.5
ENST00000344989.6
SRSF10
serine/arginine-rich splicing factor 10
chr17_-_36003487 0.12 ENST00000394367.3
ENST00000349699.2
DDX52
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr12_+_56915713 0.11 ENST00000262031.5
ENST00000552247.2
RBMS2
RNA binding motif, single stranded interacting protein 2
chr9_-_112083229 0.11 ENST00000374566.3
ENST00000374557.4
EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr1_-_217262969 0.11 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr20_-_36661826 0.11 ENST00000373448.2
ENST00000373447.3
TTI1
TELO2 interacting protein 1
chr14_+_37131058 0.10 ENST00000361487.6
PAX9
paired box 9
chr20_+_34700333 0.09 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_-_141868357 0.08 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_+_89622870 0.06 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr4_-_39979576 0.05 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr2_-_202316260 0.04 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr8_-_99837856 0.03 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr2_-_40679186 0.03 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr4_-_41216619 0.02 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr5_+_118407053 0.02 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr2_-_118771701 0.02 ENST00000376300.2
ENST00000319432.5
CCDC93
coiled-coil domain containing 93

Network of associatons between targets according to the STRING database.

First level regulatory network of CCUUCAU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.5 10.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.8 2.4 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.6 11.0 GO:0070831 basement membrane assembly(GO:0070831)
0.6 1.8 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.5 2.2 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.5 4.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.5 3.6 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5 5.0 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
0.5 4.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4 1.8 GO:0035523 protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.4 2.4 GO:2000323 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.4 3.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.4 7.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 1.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.4 7.5 GO:0051764 actin crosslink formation(GO:0051764)
0.3 1.0 GO:1902896 terminal web assembly(GO:1902896)
0.3 1.0 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.3 0.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 8.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 4.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.3 0.9 GO:1904647 response to rotenone(GO:1904647)
0.3 1.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.3 1.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.3 4.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 0.8 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.2 1.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 1.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 7.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.8 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 2.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 2.2 GO:0051382 kinetochore assembly(GO:0051382)
0.2 2.4 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.2 7.6 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.2 1.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.6 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.2 0.5 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 2.4 GO:0006449 regulation of translational termination(GO:0006449)
0.2 0.6 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 1.2 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.2 1.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 1.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 0.9 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 1.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.4 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.7 GO:1902228 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.4 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.8 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 1.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.9 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.3 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 0.8 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 3.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.3 GO:0060926 cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.1 1.6 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.1 1.1 GO:0070836 caveola assembly(GO:0070836)
0.1 0.4 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.3 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 1.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.4 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 1.4 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.8 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.1 1.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.4 GO:0034201 response to oleic acid(GO:0034201)
0.1 2.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 1.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.8 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 0.3 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 3.8 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.1 0.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 9.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 1.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 2.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 2.9 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.0 1.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 5.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 2.1 GO:0021762 substantia nigra development(GO:0021762)
0.0 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 1.3 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 1.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 4.5 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.5 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 1.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 3.9 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.0 0.0 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 11.0 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.8 4.2 GO:0001940 male pronucleus(GO:0001940)
0.6 7.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.6 5.0 GO:0071439 clathrin complex(GO:0071439)
0.5 1.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.5 7.5 GO:0043073 germ cell nucleus(GO:0043073)
0.4 4.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 1.0 GO:0044393 microspike(GO:0044393)
0.3 3.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 1.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.3 2.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.3 1.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 0.7 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 10.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 1.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 1.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.4 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.1 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 1.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 8.0 GO:0035580 specific granule lumen(GO:0035580)
0.1 7.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 7.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.5 GO:0071141 SMAD protein complex(GO:0071141)
0.1 7.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 4.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 6.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 3.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.1 GO:0005795 Golgi stack(GO:0005795)
0.0 2.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 1.0 GO:0005925 focal adhesion(GO:0005925)
0.0 3.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 3.4 GO:0001650 fibrillar center(GO:0001650)
0.0 1.9 GO:0030175 filopodium(GO:0030175)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871) axon cytoplasm(GO:1904115)
0.0 2.2 GO:0030027 lamellipodium(GO:0030027)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)
0.0 4.4 GO:0005938 cell cortex(GO:0005938)
0.0 2.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 2.6 GO:0043209 myelin sheath(GO:0043209)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:0055037 recycling endosome(GO:0055037)
0.0 0.8 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
1.1 4.3 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.8 2.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.7 7.6 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.6 8.1 GO:0038132 neuregulin binding(GO:0038132)
0.6 1.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.6 2.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.6 5.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.5 2.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.5 4.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.5 4.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.4 1.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 2.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.4 2.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.3 1.8 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 7.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.9 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.2 1.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 1.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 1.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 1.0 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 0.5 GO:0070052 collagen V binding(GO:0070052)
0.2 1.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)
0.1 7.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 5.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 3.2 GO:0070840 dynein complex binding(GO:0070840)
0.1 3.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 11.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 10.5 GO:0032947 protein complex scaffold(GO:0032947)
0.1 1.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 2.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 4.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 7.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 7.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 6.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 11.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 6.6 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.7 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.0 1.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.9 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 3.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.4 GO:0035091 phosphatidylinositol binding(GO:0035091)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 5.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 5.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 6.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 7.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 3.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 3.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6 2.4 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.3 7.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.3 8.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 7.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 8.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 5.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 6.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 6.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 2.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 6.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 10.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 3.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 7.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 2.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 3.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.6 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex