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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CDC5L

Z-value: 0.65

Motif logo

Transcription factors associated with CDC5L

Gene Symbol Gene ID Gene Info
ENSG00000096401.7 cell division cycle 5 like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDC5Lhg19_v2_chr6_+_44355257_44355315-0.344.0e-07Click!

Activity profile of CDC5L motif

Sorted Z-values of CDC5L motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_69597810 18.70 ENST00000483798.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr6_-_32557610 10.71 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr16_-_71610985 10.48 ENST00000355962.4
tyrosine aminotransferase
chr12_-_10542617 10.06 ENST00000240618.6
killer cell lectin-like receptor subfamily K, member 1
chr4_+_155484155 9.23 ENST00000509493.1
fibrinogen beta chain
chr12_-_53601055 7.99 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
integrin, beta 7
chr10_-_69597915 7.96 ENST00000225171.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr11_-_118213331 7.55 ENST00000392884.2
CD3d molecule, delta (CD3-TCR complex)
chr19_-_17185848 7.04 ENST00000593360.1
HAUS augmin-like complex, subunit 8
chr12_-_91546926 7.04 ENST00000550758.1
decorin
chr6_-_33041378 6.99 ENST00000428995.1
major histocompatibility complex, class II, DP alpha 1
chr15_-_42076229 6.71 ENST00000597767.1
Uncharacterized protein
chr6_-_32498046 6.70 ENST00000374975.3
major histocompatibility complex, class II, DR beta 5
chr12_-_53601000 6.48 ENST00000338737.4
ENST00000549086.2
integrin, beta 7
chr12_-_91573249 6.32 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr11_-_118213455 6.21 ENST00000300692.4
CD3d molecule, delta (CD3-TCR complex)
chr9_-_73029540 6.09 ENST00000377126.2
Kruppel-like factor 9
chr11_-_114466477 6.08 ENST00000375478.3
neurexophilin and PC-esterase domain family, member 4
chr14_-_21516590 6.01 ENST00000555026.1
NDRG family member 2
chr13_-_38172863 6.01 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr4_+_155484103 5.92 ENST00000302068.4
fibrinogen beta chain
chr2_+_90248739 5.79 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr5_+_54398463 5.74 ENST00000274306.6
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr1_+_152635854 5.65 ENST00000368784.1
late cornified envelope 2D
chr2_+_127413481 5.65 ENST00000259254.4
glycophorin C (Gerbich blood group)
chr17_+_56315936 5.65 ENST00000543544.1
lactoperoxidase
chr11_+_31391381 5.44 ENST00000465995.1
ENST00000536040.1
DnaJ (Hsp40) homolog, subfamily C, member 24
chr1_+_244998602 5.42 ENST00000411948.2
COX20 cytochrome C oxidase assembly factor
chr8_-_86253888 5.28 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr2_-_100939195 5.26 ENST00000393437.3
LON peptidase N-terminal domain and ring finger 2
chr1_+_25598989 5.17 ENST00000454452.2
Rh blood group, D antigen
chr9_-_93405352 4.95 ENST00000375765.3
DIRAS family, GTP-binding RAS-like 2
chr1_+_158985457 4.94 ENST00000567661.1
ENST00000474473.1
interferon, gamma-inducible protein 16
chr11_-_118213360 4.81 ENST00000529594.1
CD3d molecule, delta (CD3-TCR complex)
chr12_-_91573316 4.79 ENST00000393155.1
decorin
chr5_+_54320078 4.76 ENST00000231009.2
granzyme K (granzyme 3; tryptase II)
chr2_+_189839046 4.68 ENST00000304636.3
ENST00000317840.5
collagen, type III, alpha 1
chr2_+_102721023 4.65 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr14_-_106725723 4.65 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr12_+_133757995 4.51 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
zinc finger protein 268
chr6_-_52705641 4.45 ENST00000370989.2
glutathione S-transferase alpha 5
chr17_-_2996290 4.45 ENST00000331459.1
olfactory receptor, family 1, subfamily D, member 2
chr4_-_68749745 4.42 ENST00000283916.6
transmembrane protease, serine 11D
chr1_+_152974218 4.13 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
small proline-rich protein 3
chr11_-_114466471 4.06 ENST00000424261.2
neurexophilin and PC-esterase domain family, member 4
chr3_+_101443476 4.05 ENST00000327230.4
ENST00000494050.1
centrosomal protein 97kDa
chr14_-_99737822 4.02 ENST00000345514.2
ENST00000443726.2
B-cell CLL/lymphoma 11B (zinc finger protein)
chr6_+_161123270 3.88 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr5_+_156607829 3.86 ENST00000422843.3
IL2-inducible T-cell kinase
chr2_+_166095898 3.84 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr1_-_226926864 3.81 ENST00000429204.1
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr12_-_371994 3.81 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
solute carrier family 6 (neurotransmitter transporter), member 13
chr15_+_32933866 3.80 ENST00000300175.4
ENST00000413748.2
ENST00000494364.1
ENST00000497208.1
secretogranin V (7B2 protein)
chr14_-_99737565 3.78 ENST00000357195.3
B-cell CLL/lymphoma 11B (zinc finger protein)
chr11_+_55029628 3.76 ENST00000417545.2
tripartite motif containing 48
chr1_+_89829610 3.75 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr21_+_10862622 3.74 ENST00000302092.5
ENST00000559480.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr2_-_175462456 3.72 ENST00000409891.1
ENST00000410117.1
WAS/WASL interacting protein family, member 1
chr17_+_73452695 3.65 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
KIAA0195
chr2_-_89459813 3.63 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr17_+_37856214 3.59 ENST00000445658.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr1_+_196621002 3.56 ENST00000367429.4
ENST00000439155.2
complement factor H
chr17_+_56315787 3.56 ENST00000262290.4
ENST00000421678.2
lactoperoxidase
chr12_-_71182695 3.54 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr14_+_22458631 3.53 ENST00000390444.1
T cell receptor alpha variable 16
chr1_-_89591749 3.51 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr1_+_198608146 3.48 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr4_+_75023816 3.47 ENST00000395759.2
ENST00000331145.6
ENST00000359107.5
ENST00000325278.6
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr5_-_177207634 3.42 ENST00000513554.1
ENST00000440605.3
family with sequence similarity 153, member A
chr4_-_68749699 3.42 ENST00000545541.1
transmembrane protease, serine 11D
chr10_-_73848764 3.41 ENST00000317376.4
ENST00000412663.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr6_+_32709119 3.41 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr12_-_45307711 3.30 ENST00000333837.4
ENST00000551949.1
NEL-like 2 (chicken)
chr6_+_26156551 3.29 ENST00000304218.3
histone cluster 1, H1e
chr3_-_194072019 3.24 ENST00000429275.1
ENST00000323830.3
carboxypeptidase N, polypeptide 2
chr8_+_21911054 3.22 ENST00000519850.1
ENST00000381470.3
dematin actin binding protein
chr3_+_122044084 3.15 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr3_+_73110810 3.09 ENST00000533473.1
endogenous Bornavirus-like nucleoprotein 2
chr9_-_21368075 3.05 ENST00000449498.1
interferon, alpha 13
chr6_-_39197226 3.05 ENST00000359534.3
potassium channel, subfamily K, member 5
chr2_+_67624430 3.05 ENST00000272342.5
Ewing tumor-associated antigen 1
chrX_-_48056199 3.03 ENST00000311798.1
ENST00000347757.1
synovial sarcoma, X breakpoint 5
chr15_-_22448819 3.02 ENST00000604066.1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr9_-_21351377 3.02 ENST00000380210.1
interferon, alpha 6
chrX_+_77166172 3.00 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr16_+_72088376 3.00 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr12_+_79439405 2.96 ENST00000552744.1
synaptotagmin I
chr12_-_21927736 2.95 ENST00000240662.2
potassium inwardly-rectifying channel, subfamily J, member 8
chr2_+_85921522 2.94 ENST00000409696.3
granulysin
chr10_-_73848531 2.93 ENST00000373109.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr2_+_85921414 2.90 ENST00000263863.4
ENST00000524600.1
granulysin
chr21_+_43619796 2.89 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr3_+_48282587 2.88 ENST00000354698.3
ENST00000427617.2
ENST00000412564.1
ENST00000440261.2
zinc finger protein 589
chr17_-_76713100 2.85 ENST00000585509.1
cytohesin 1
chr2_-_74570520 2.83 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr3_+_46412345 2.82 ENST00000292303.4
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr1_+_196621156 2.81 ENST00000359637.2
complement factor H
chr11_+_73661364 2.77 ENST00000339764.1
DnaJ (Hsp40) homolog, subfamily B, member 13
chr6_-_26250835 2.76 ENST00000446824.2
histone cluster 1, H3f
chr4_+_170541678 2.69 ENST00000360642.3
ENST00000512813.1
chloride channel, voltage-sensitive 3
chr18_+_77160282 2.68 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr17_+_41003166 2.66 ENST00000308423.2
amine oxidase, copper containing 3
chr1_+_22351977 2.65 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
long intergenic non-protein coding RNA 339
chr16_-_1843720 2.63 ENST00000415638.3
ENST00000215539.3
insulin-like growth factor binding protein, acid labile subunit
chrX_+_103031758 2.62 ENST00000303958.2
ENST00000361621.2
proteolipid protein 1
chr11_+_119076745 2.61 ENST00000264033.4
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr3_+_178276488 2.60 ENST00000432997.1
ENST00000455865.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr21_+_37692481 2.60 ENST00000400485.1
MORC family CW-type zinc finger 3
chr5_+_140213815 2.59 ENST00000525929.1
ENST00000378125.3
protocadherin alpha 7
chr14_-_106733624 2.55 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr17_+_15602891 2.53 ENST00000421016.1
ENST00000593105.1
ENST00000580259.1
ENST00000583566.1
ENST00000472486.1
ENST00000395894.2
ENST00000581529.1
ENST00000579694.1
ENST00000580393.1
ENST00000585194.1
ENST00000583031.1
ENST00000464847.2
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr17_+_37856253 2.53 ENST00000540147.1
ENST00000584450.1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr12_-_21487829 2.53 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
solute carrier organic anion transporter family, member 1A2
chr11_-_13517565 2.53 ENST00000282091.1
ENST00000529816.1
parathyroid hormone
chr4_+_128554081 2.51 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr13_+_23755099 2.51 ENST00000537476.1
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr15_-_20170354 2.51 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr17_-_47755338 2.50 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chr1_+_152956549 2.48 ENST00000307122.2
small proline-rich protein 1A
chr2_+_210517895 2.47 ENST00000447185.1
microtubule-associated protein 2
chr11_-_236326 2.45 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
sirtuin 3
chr9_-_6470375 2.44 ENST00000355513.4
chromosome 9 open reading frame 38
chr11_-_130786400 2.38 ENST00000265909.4
sorting nexin 19
chr13_+_111855414 2.37 ENST00000375737.5
Rho guanine nucleotide exchange factor (GEF) 7
chr10_+_96698406 2.36 ENST00000260682.6
cytochrome P450, family 2, subfamily C, polypeptide 9
chr2_+_66662510 2.35 ENST00000272369.9
ENST00000407092.2
Meis homeobox 1
chr5_+_147443534 2.34 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
serine peptidase inhibitor, Kazal type 5
chr5_-_127418755 2.33 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3
chr5_-_138210977 2.32 ENST00000274711.6
ENST00000521094.2
leucine rich repeat transmembrane neuronal 2
chr6_+_27107053 2.31 ENST00000354348.2
histone cluster 1, H4i
chr2_-_110962544 2.30 ENST00000355301.4
ENST00000445609.2
ENST00000417665.1
ENST00000418527.1
ENST00000316534.4
ENST00000393272.3
nephronophthisis 1 (juvenile)
chr10_-_74114714 2.30 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DnaJ (Hsp40) homolog, subfamily B, member 12
chr1_+_38022513 2.29 ENST00000296218.7
dynein, axonemal, light intermediate chain 1
chr14_-_106668095 2.28 ENST00000390606.2
immunoglobulin heavy variable 3-20
chr12_+_9980069 2.28 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
killer cell lectin-like receptor subfamily F, member 1
chr1_+_156338993 2.26 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
Rh family, B glycoprotein (gene/pseudogene)
chr6_+_35996859 2.25 ENST00000472333.1
mitogen-activated protein kinase 14
chrX_-_15402498 2.25 ENST00000297904.3
c-fos induced growth factor (vascular endothelial growth factor D)
chr15_+_42066632 2.25 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
mitogen-activated protein kinase binding protein 1
chr15_-_99789736 2.23 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
tetratricopeptide repeat domain 23
chr22_-_40929812 2.23 ENST00000422851.1
megakaryoblastic leukemia (translocation) 1
chr11_+_64794875 2.21 ENST00000377244.3
ENST00000534637.1
ENST00000524831.1
sorting nexin 15
chr15_-_20193370 2.21 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr7_+_138943265 2.20 ENST00000483726.1
ubinuclein 2
chr1_+_241695670 2.20 ENST00000366557.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr4_+_118955500 2.17 ENST00000296499.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr14_-_71001708 2.17 ENST00000256389.3
ADAM metallopeptidase domain 20
chr5_+_161495038 2.16 ENST00000393933.4
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr4_-_76957214 2.16 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr11_-_83984231 2.14 ENST00000330014.6
ENST00000537455.1
ENST00000376106.3
ENST00000418306.2
ENST00000531015.1
discs, large homolog 2 (Drosophila)
chr2_-_113542063 2.13 ENST00000263339.3
interleukin 1, alpha
chr5_+_140800638 2.12 ENST00000398587.2
ENST00000518882.1
protocadherin gamma subfamily A, 11
chr20_+_1246908 2.10 ENST00000381873.3
ENST00000381867.1
syntaphilin
chr7_-_113559104 2.10 ENST00000284601.3
protein phosphatase 1, regulatory subunit 3A
chr12_+_18414446 2.09 ENST00000433979.1
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr14_-_80677815 2.09 ENST00000557125.1
ENST00000555750.1
deiodinase, iodothyronine, type II
chr7_+_96634850 2.07 ENST00000518156.2
distal-less homeobox 6
chr17_-_7493390 2.06 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SRY (sex determining region Y)-box 15
chr1_-_150738261 2.06 ENST00000448301.2
ENST00000368985.3
cathepsin S
chr2_+_241807870 2.05 ENST00000307503.3
alanine-glyoxylate aminotransferase
chr6_-_27840099 2.05 ENST00000328488.2
histone cluster 1, H3i
chr3_+_151531810 2.02 ENST00000232892.7
arylacetamide deacetylase
chr17_+_37856299 2.02 ENST00000269571.5
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr2_+_128848740 2.01 ENST00000375990.3
UDP-glucose glycoprotein glucosyltransferase 1
chr2_+_113931513 2.01 ENST00000245796.6
ENST00000441564.3
pleckstrin and Sec7 domain containing 4
chr1_+_66458072 2.01 ENST00000423207.2
phosphodiesterase 4B, cAMP-specific
chr8_+_24772455 2.00 ENST00000433454.2
neurofilament, medium polypeptide
chr14_-_69261310 2.00 ENST00000336440.3
ZFP36 ring finger protein-like 1
chr17_-_64225508 1.99 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr10_+_51549498 1.98 ENST00000358559.2
ENST00000298239.6
microseminoprotein, beta-
chr1_+_9599540 1.98 ENST00000302692.6
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr4_-_48082192 1.95 ENST00000507351.1
TXK tyrosine kinase
chr14_+_70918874 1.95 ENST00000603540.1
ADAM metallopeptidase domain 21
chr4_+_80584903 1.94 ENST00000506460.1
RP11-452C8.1
chr6_+_41604747 1.93 ENST00000419164.1
ENST00000373051.2
MyoD family inhibitor
chr4_+_106631966 1.92 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr14_-_106453155 1.90 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr1_+_110254850 1.90 ENST00000369812.5
ENST00000256593.3
ENST00000369813.1
glutathione S-transferase mu 5
chr20_+_43104508 1.88 ENST00000262605.4
ENST00000372904.3
tocopherol (alpha) transfer protein-like
chr20_-_18477862 1.88 ENST00000337227.4
retinoblastoma binding protein 9
chr19_-_33360647 1.86 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr17_-_59668550 1.85 ENST00000521764.1
nascent polypeptide-associated complex alpha subunit 2
chrX_+_138612889 1.84 ENST00000218099.2
ENST00000394090.2
coagulation factor IX
chr2_+_54350316 1.84 ENST00000606865.1
acylphosphatase 2, muscle type
chr2_-_163100045 1.84 ENST00000188790.4
fibroblast activation protein, alpha
chr4_+_164265035 1.81 ENST00000338566.3
neuropeptide Y receptor Y5
chr4_-_70725856 1.80 ENST00000226444.3
sulfotransferase family 1E, estrogen-preferring, member 1
chr14_+_22963806 1.79 ENST00000390493.1
T cell receptor alpha joining 44
chr1_-_104238912 1.79 ENST00000330330.5
amylase, alpha 1B (salivary)
chr7_+_134430212 1.78 ENST00000436461.2
caldesmon 1
chr19_+_15852203 1.74 ENST00000305892.1
olfactory receptor, family 10, subfamily H, member 3
chr2_-_222436988 1.72 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPH receptor A4
chr6_+_29424958 1.71 ENST00000377136.1
ENST00000377133.1
olfactory receptor, family 2, subfamily H, member 1
chr18_-_10701979 1.67 ENST00000538948.1
ENST00000285141.4
piezo-type mechanosensitive ion channel component 2
chr12_+_62860581 1.67 ENST00000393632.2
ENST00000393630.3
ENST00000280379.6
ENST00000546600.1
ENST00000552738.1
ENST00000393629.2
ENST00000552115.1
MON2 homolog (S. cerevisiae)
chr6_-_41254403 1.66 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
triggering receptor expressed on myeloid cells 1
chr13_+_23755054 1.66 ENST00000218867.3
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chrX_-_48216101 1.65 ENST00000298396.2
ENST00000376893.3
synovial sarcoma, X breakpoint 3
chr14_+_39703112 1.64 ENST00000555143.1
ENST00000280082.3
melanoma inhibitory activity 2
chr7_+_29519486 1.62 ENST00000409041.4
chimerin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CDC5L

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.5 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
3.4 10.1 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
2.1 10.7 GO:0002399 MHC class II protein complex assembly(GO:0002399)
2.0 6.0 GO:1990523 bone regeneration(GO:1990523)
2.0 5.9 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
1.9 7.8 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
1.9 5.8 GO:0002818 intracellular defense response(GO:0002818)
1.7 22.4 GO:0045059 positive thymic T cell selection(GO:0045059)
1.6 4.7 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.5 15.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.5 18.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.5 10.5 GO:0006572 tyrosine catabolic process(GO:0006572)
1.3 3.9 GO:2000048 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.2 2.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
1.1 4.6 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
1.0 8.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.0 3.0 GO:0071284 cellular response to lead ion(GO:0071284)
1.0 3.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.0 3.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.0 2.9 GO:0009726 detection of endogenous stimulus(GO:0009726)
1.0 4.8 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.9 6.1 GO:0051414 response to cortisol(GO:0051414)
0.8 2.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.8 0.8 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.8 3.3 GO:0097325 melanocyte proliferation(GO:0097325)
0.8 2.4 GO:1990502 dense core granule maturation(GO:1990502)
0.8 2.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.7 3.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.7 3.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.7 2.1 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.7 2.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.7 0.7 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.7 3.5 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.7 2.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.7 2.1 GO:0048627 myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.7 2.0 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.7 5.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.7 2.0 GO:0097359 UDP-glucosylation(GO:0097359)
0.7 2.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.7 2.0 GO:0048382 mesendoderm development(GO:0048382)
0.7 2.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.7 2.0 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.6 1.8 GO:0006711 estrogen catabolic process(GO:0006711)
0.6 3.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.6 4.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 5.7 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.6 1.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.6 2.8 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.6 2.3 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.6 6.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 3.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.5 2.7 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.5 6.0 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.5 1.5 GO:0016095 polyprenol catabolic process(GO:0016095)
0.5 3.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.5 2.8 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4 2.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.4 2.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4 3.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.4 3.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.4 10.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 2.6 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.4 2.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.4 1.1 GO:0042495 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.4 1.1 GO:0048073 regulation of eye pigmentation(GO:0048073) positive regulation of eye pigmentation(GO:0048075)
0.4 2.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 2.4 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.3 2.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 8.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 1.7 GO:0072672 neutrophil extravasation(GO:0072672)
0.3 3.8 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.3 4.0 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.3 1.9 GO:0015811 L-cystine transport(GO:0015811)
0.3 2.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.3 1.8 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.3 3.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 10.0 GO:0018149 peptide cross-linking(GO:0018149)
0.3 7.4 GO:0015695 organic cation transport(GO:0015695)
0.3 1.5 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.2 2.0 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 1.5 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.2 0.7 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2 1.0 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 4.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 11.1 GO:0010107 potassium ion import(GO:0010107)
0.2 1.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 16.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 2.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 2.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 2.0 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.2 3.0 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.2 3.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 0.8 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.2 2.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 2.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 2.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 9.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 2.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 3.9 GO:0031297 replication fork processing(GO:0031297)
0.2 2.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 2.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 1.5 GO:0015705 iodide transport(GO:0015705)
0.2 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 2.6 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 2.6 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.8 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.2 2.3 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.2 2.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.9 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 3.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 1.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 2.4 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 17.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 3.1 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.9 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 1.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 1.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.9 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 2.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 7.9 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 2.2 GO:0071420 cellular response to histamine(GO:0071420)
0.1 4.9 GO:0030224 monocyte differentiation(GO:0030224)
0.1 16.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 2.6 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 0.8 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 4.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 1.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.6 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.1 1.4 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 3.6 GO:0016486 peptide hormone processing(GO:0016486)
0.1 3.8 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.9 GO:0035690 cellular response to drug(GO:0035690)
0.1 0.6 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.7 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 2.8 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 2.1 GO:0010447 response to acidic pH(GO:0010447)
0.1 1.0 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 4.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.8 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.8 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 1.3 GO:0030220 platelet formation(GO:0030220)
0.1 0.8 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.3 GO:0033622 integrin activation(GO:0033622)
0.1 0.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 2.1 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 1.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 0.6 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.1 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 1.0 GO:0042730 fibrinolysis(GO:0042730)
0.0 1.4 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 6.9 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 1.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.8 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 1.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.8 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 2.0 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.0 0.9 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 1.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 1.0 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.5 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0070375 ERK5 cascade(GO:0070375)
0.0 0.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.5 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) energy reserve metabolic process(GO:0006112) glucan metabolic process(GO:0044042) cellular polysaccharide metabolic process(GO:0044264)
0.0 2.5 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.7 GO:0007595 lactation(GO:0007595)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.0 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 1.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.9 GO:0060021 palate development(GO:0060021)
0.0 3.2 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.6 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.4 GO:0050954 sensory perception of mechanical stimulus(GO:0050954)
0.0 0.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.8 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 1.1 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.5 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.7 18.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.4 4.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.3 27.8 GO:0042613 MHC class II protein complex(GO:0042613)
1.3 18.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.2 15.2 GO:0005577 fibrinogen complex(GO:0005577)
0.8 5.8 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.8 5.0 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.8 7.0 GO:0070652 HAUS complex(GO:0070652)
0.8 3.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 3.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.5 4.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 2.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 4.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 1.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.4 2.9 GO:0005593 FACIT collagen trimer(GO:0005593)
0.3 17.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 2.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 6.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 3.3 GO:0071438 invadopodium membrane(GO:0071438)
0.3 2.4 GO:0000322 storage vacuole(GO:0000322)
0.3 2.1 GO:0036021 endolysosome lumen(GO:0036021)
0.3 5.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 2.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.3 1.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.3 1.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 1.3 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.2 1.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 3.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 2.6 GO:0016600 flotillin complex(GO:0016600)
0.2 0.9 GO:0005899 insulin receptor complex(GO:0005899)
0.2 10.0 GO:0001533 cornified envelope(GO:0001533)
0.2 0.6 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.2 1.5 GO:0000125 PCAF complex(GO:0000125)
0.1 2.0 GO:0005883 neurofilament(GO:0005883)
0.1 2.9 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 2.0 GO:0030478 actin cap(GO:0030478)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 3.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 2.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 3.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 3.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 27.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.2 GO:0001772 immunological synapse(GO:0001772)
0.1 1.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 6.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.7 GO:0097546 ciliary base(GO:0097546)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 2.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 2.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 4.6 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 2.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 2.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 5.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 5.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 5.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 10.8 GO:0043209 myelin sheath(GO:0043209)
0.0 5.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 3.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 4.0 GO:0005884 actin filament(GO:0005884)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 3.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 4.8 GO:0030426 growth cone(GO:0030426)
0.0 7.5 GO:0005911 cell-cell junction(GO:0005911)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 2.5 GO:0031514 motile cilium(GO:0031514)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 2.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0031904 endosome lumen(GO:0031904)
0.0 26.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 3.1 GO:0030424 axon(GO:0030424)
0.0 3.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.0 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 4.8 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.5 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.2 4.7 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
1.2 3.5 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
1.1 6.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.0 3.0 GO:0032767 copper-dependent protein binding(GO:0032767)
1.0 2.9 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.9 2.7 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.8 2.3 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.7 10.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.7 8.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.7 2.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.7 2.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.7 5.3 GO:0004064 arylesterase activity(GO:0004064)
0.6 19.3 GO:0042605 peptide antigen binding(GO:0042605)
0.6 3.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 3.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.6 1.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.6 3.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.6 3.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 3.3 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.5 3.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 1.5 GO:0046848 hydroxyapatite binding(GO:0046848)
0.5 3.0 GO:0030492 hemoglobin binding(GO:0030492)
0.5 1.5 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.5 1.5 GO:0070052 collagen V binding(GO:0070052)
0.5 3.9 GO:1990405 protein antigen binding(GO:1990405)
0.5 3.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.5 2.4 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.5 2.7 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.4 2.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 1.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.4 2.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.4 1.5 GO:0047718 enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.4 26.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 2.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 2.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 10.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 4.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 4.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.3 10.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 17.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 1.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.3 3.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 2.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 1.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 1.5 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 0.9 GO:0032089 NACHT domain binding(GO:0032089)
0.3 6.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 0.8 GO:0005148 prolactin receptor binding(GO:0005148)
0.3 1.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 2.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 7.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 1.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.2 0.7 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.2 3.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 1.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 3.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 2.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.3 GO:0004630 phospholipase D activity(GO:0004630)
0.2 2.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 1.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 5.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 3.7 GO:0005522 profilin binding(GO:0005522)
0.2 1.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.6 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 0.8 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 0.8 GO:0016499 orexin receptor activity(GO:0016499)
0.2 4.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 9.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 0.9 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 9.2 GO:0004601 peroxidase activity(GO:0004601)
0.2 1.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.2 2.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 2.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 2.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 2.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 3.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 3.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 2.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.5 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 2.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 13.6 GO:0051087 chaperone binding(GO:0051087)
0.1 2.4 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.1 3.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 4.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 9.4 GO:0003823 antigen binding(GO:0003823)
0.1 0.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 1.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 2.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 10.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 2.0 GO:0008483 transaminase activity(GO:0008483)
0.1 2.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 2.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 3.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 2.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 2.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 22.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.5 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 1.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.4 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 6.8 GO:0051082 unfolded protein binding(GO:0051082)
0.1 2.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 2.0 GO:0008198 ferrous iron binding(GO:0008198)
0.1 6.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.9 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 1.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 4.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 2.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 4.9 GO:0060089 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.1 GO:0019902 phosphatase binding(GO:0019902)
0.0 12.1 GO:0004888 transmembrane signaling receptor activity(GO:0004888)
0.0 1.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.2 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.7 GO:0008083 growth factor activity(GO:0008083)
0.0 1.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 28.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.5 14.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 22.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 18.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 3.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 8.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 15.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 15.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.2 8.2 NABA COLLAGENS Genes encoding collagen proteins
0.2 4.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 10.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.0 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 4.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 2.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 12.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 8.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 4.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 7.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 46.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.9 15.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.7 2.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.7 3.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.7 2.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.7 18.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 3.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 8.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 6.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 3.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 22.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 5.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 3.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 4.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 1.6 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.2 9.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 1.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 4.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 5.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.2 9.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 3.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 5.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 3.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 2.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 2.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules