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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CEBPB

Z-value: 0.16

Motif logo

Transcription factors associated with CEBPB

Gene Symbol Gene ID Gene Info
ENSG00000172216.4 CCAAT enhancer binding protein beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPBhg19_v2_chr20_+_48807351_488073840.274.4e-05Click!

Activity profile of CEBPB motif

Sorted Z-values of CEBPB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_134070250 16.76 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
chr20_+_361261 14.34 ENST00000217233.3
tribbles pseudokinase 3
chr2_-_216300784 13.84 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr3_+_157154578 11.88 ENST00000295927.3
pentraxin 3, long
chr11_+_92085707 11.31 ENST00000525166.1
FAT atypical cadherin 3
chr11_+_92085262 9.86 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr12_+_57624085 9.55 ENST00000553474.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr17_-_64216748 8.96 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr4_-_139163491 8.45 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr12_+_57623477 8.28 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr12_+_57623869 8.26 ENST00000414700.3
ENST00000557703.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr5_-_172756506 7.53 ENST00000265087.4
stanniocalcin 2
chr11_-_102668879 7.46 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr12_+_57624119 7.43 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr4_-_155533787 7.32 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr1_-_36948879 7.31 ENST00000373106.1
ENST00000373104.1
ENST00000373103.1
colony stimulating factor 3 receptor (granulocyte)
chr17_+_1665345 7.25 ENST00000576406.1
ENST00000571149.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr20_+_56136136 7.11 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr19_-_47288162 7.10 ENST00000594991.1
solute carrier family 1 (neutral amino acid transporter), member 5
chr2_+_211421262 7.00 ENST00000233072.5
carbamoyl-phosphate synthase 1, mitochondrial
chr19_-_47287990 6.99 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr14_-_100841670 6.81 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
tryptophanyl-tRNA synthetase
chr3_-_138763734 6.33 ENST00000413199.1
ENST00000502927.2
proline rich 23C
chr1_-_36945097 6.14 ENST00000331941.5
ENST00000418048.2
ENST00000338937.5
ENST00000440588.2
colony stimulating factor 3 receptor (granulocyte)
chr1_+_212782012 6.10 ENST00000341491.4
ENST00000366985.1
activating transcription factor 3
chr6_+_31895467 6.04 ENST00000556679.1
ENST00000456570.1
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_-_204380919 5.94 ENST00000367188.4
protein phosphatase 1, regulatory subunit 15B
chr5_+_33441053 5.51 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
threonyl-tRNA synthetase
chr5_+_33440802 5.45 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
threonyl-tRNA synthetase
chr14_-_100841930 5.21 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
tryptophanyl-tRNA synthetase
chr15_+_41245160 5.20 ENST00000444189.2
ENST00000446533.3
ChaC, cation transport regulator homolog 1 (E. coli)
chr22_+_35776828 5.12 ENST00000216117.8
heme oxygenase (decycling) 1
chr3_+_186435137 4.73 ENST00000447445.1
kininogen 1
chr3_-_48057890 4.68 ENST00000434267.1
microtubule-associated protein 4
chr21_-_44495964 4.66 ENST00000398168.1
ENST00000398165.3
cystathionine-beta-synthase
chr5_+_150400124 4.65 ENST00000388825.4
ENST00000521650.1
ENST00000517973.1
glutathione peroxidase 3 (plasma)
chr16_+_72088376 4.62 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr12_+_57849048 4.57 ENST00000266646.2
inhibin, beta E
chr16_-_28550348 4.56 ENST00000324873.6
nuclear protein, transcriptional regulator, 1
chr21_-_44495919 4.46 ENST00000398158.1
cystathionine-beta-synthase
chr3_+_186435065 4.33 ENST00000287611.2
ENST00000265023.4
kininogen 1
chr20_+_36974759 4.14 ENST00000217407.2
lipopolysaccharide binding protein
chr17_+_1665253 4.12 ENST00000254722.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr2_-_160654745 4.11 ENST00000259053.4
ENST00000429078.2
CD302 molecule
chr12_-_96390063 4.04 ENST00000541929.1
histidine ammonia-lyase
chr12_-_57914275 4.02 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DNA-damage-inducible transcript 3
chr16_-_28550320 3.90 ENST00000395641.2
nuclear protein, transcriptional regulator, 1
chr12_-_54691668 3.81 ENST00000553198.1
nuclear factor, erythroid 2
chr5_+_150020214 3.81 ENST00000307662.4
synaptopodin
chr5_-_137878887 3.81 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
eukaryotic translation termination factor 1
chr6_+_31895480 3.79 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chrX_+_24072833 3.67 ENST00000253039.4
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_+_99127225 3.60 ENST00000370189.5
ENST00000529992.1
sorting nexin 7
chr6_+_30687978 3.52 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr9_+_137218362 3.40 ENST00000481739.1
retinoid X receptor, alpha
chr11_+_118955583 3.20 ENST00000278715.3
ENST00000536813.1
ENST00000537841.1
ENST00000542729.1
ENST00000546302.1
ENST00000442944.2
ENST00000544387.1
ENST00000543090.1
hydroxymethylbilane synthase
chr11_-_3078616 2.87 ENST00000401769.3
ENST00000278224.9
ENST00000397114.3
ENST00000380525.4
cysteinyl-tRNA synthetase
chr17_-_79895097 2.86 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
pyrroline-5-carboxylate reductase 1
chr3_+_12392971 2.82 ENST00000287820.6
peroxisome proliferator-activated receptor gamma
chr12_+_6644443 2.71 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr17_-_79895154 2.61 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
pyrroline-5-carboxylate reductase 1
chr19_+_33865218 2.58 ENST00000585933.2
CCAAT/enhancer binding protein (C/EBP), gamma
chr2_+_121010413 2.54 ENST00000404963.3
v-ral simian leukemia viral oncogene homolog B
chr4_-_70725856 2.51 ENST00000226444.3
sulfotransferase family 1E, estrogen-preferring, member 1
chr17_-_46703826 2.49 ENST00000550387.1
ENST00000311177.5
homeobox B9
chr3_+_42897512 2.48 ENST00000493193.1
atypical chemokine receptor 2
chr1_-_149908217 2.46 ENST00000369140.3
myotubularin related protein 11
chr6_+_31895254 2.44 ENST00000299367.5
ENST00000442278.2
complement component 2
chr7_-_76829125 2.44 ENST00000248598.5
fibrinogen-like 2
chr11_-_3078838 2.44 ENST00000397111.5
cysteinyl-tRNA synthetase
chr5_-_35230434 2.40 ENST00000504500.1
prolactin receptor
chr14_-_92413727 2.37 ENST00000267620.10
fibulin 5
chr15_+_96869165 2.34 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr12_+_56390964 2.33 ENST00000356124.4
ENST00000266971.3
ENST00000394115.2
ENST00000547586.1
ENST00000552258.1
ENST00000548274.1
ENST00000546833.1
sulfite oxidase
chr9_+_2621798 2.30 ENST00000382100.3
very low density lipoprotein receptor
chr7_-_50860565 2.29 ENST00000403097.1
growth factor receptor-bound protein 10
chr12_-_6451235 2.25 ENST00000440083.2
ENST00000162749.2
tumor necrosis factor receptor superfamily, member 1A
chr11_+_62649158 2.24 ENST00000539891.1
ENST00000536981.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr2_-_217559517 2.21 ENST00000449583.1
insulin-like growth factor binding protein 5
chr5_-_141704566 2.18 ENST00000344120.4
ENST00000434127.2
sprouty homolog 4 (Drosophila)
chr12_-_96390108 2.16 ENST00000538703.1
ENST00000261208.3
histidine ammonia-lyase
chr1_-_220220000 2.12 ENST00000366923.3
glutamyl-prolyl-tRNA synthetase
chr12_-_25102252 2.10 ENST00000261192.7
branched chain amino-acid transaminase 1, cytosolic
chr20_-_32700075 2.10 ENST00000374980.2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr3_-_49722523 2.10 ENST00000448220.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr2_+_113885138 2.10 ENST00000409930.3
interleukin 1 receptor antagonist
chr12_-_25101920 2.06 ENST00000539780.1
ENST00000546285.1
ENST00000342945.5
branched chain amino-acid transaminase 1, cytosolic
chr2_+_28618532 2.06 ENST00000545753.1
FOS-like antigen 2
chr5_+_125758865 2.06 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr5_+_125758813 2.04 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr5_+_38846101 2.02 ENST00000274276.3
oncostatin M receptor
chr14_-_92413353 2.00 ENST00000556154.1
fibulin 5
chr1_-_149908710 2.00 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
myotubularin related protein 11
chr7_+_28725585 2.00 ENST00000396298.2
cAMP responsive element binding protein 5
chr5_-_35230649 1.96 ENST00000382002.5
prolactin receptor
chr16_-_57809015 1.90 ENST00000540079.2
ENST00000569222.1
kinesin family member C3
chr1_+_221051699 1.90 ENST00000366903.6
H2.0-like homeobox
chr2_+_5832799 1.87 ENST00000322002.3
SRY (sex determining region Y)-box 11
chr10_+_95848824 1.82 ENST00000371385.3
ENST00000371375.1
phospholipase C, epsilon 1
chr19_-_54824344 1.81 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr1_-_220219775 1.74 ENST00000609181.1
glutamyl-prolyl-tRNA synthetase
chrX_-_109683446 1.69 ENST00000372057.1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr19_-_11347173 1.69 ENST00000587656.1
dedicator of cytokinesis 6
chr3_+_138067666 1.66 ENST00000475711.1
ENST00000464896.1
muscle RAS oncogene homolog
chr12_+_123868320 1.62 ENST00000402868.3
ENST00000330479.4
SET domain containing (lysine methyltransferase) 8
chr6_-_55739542 1.58 ENST00000446683.2
bone morphogenetic protein 5
chr11_-_119999611 1.57 ENST00000529044.1
tripartite motif containing 29
chr11_+_47279504 1.56 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
nuclear receptor subfamily 1, group H, member 3
chrX_-_106243451 1.51 ENST00000355610.4
ENST00000535534.1
MORC family CW-type zinc finger 4
chr11_-_119999539 1.50 ENST00000541857.1
tripartite motif containing 29
chr12_+_21207503 1.50 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr16_+_58426296 1.50 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
GINS complex subunit 3 (Psf3 homolog)
chr18_+_61420169 1.47 ENST00000425392.1
ENST00000336429.2
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_-_6451186 1.46 ENST00000540022.1
ENST00000536194.1
tumor necrosis factor receptor superfamily, member 1A
chr1_-_221915418 1.45 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chr12_-_56236690 1.43 ENST00000322569.4
matrix metallopeptidase 19
chr8_-_21966893 1.40 ENST00000522405.1
ENST00000522379.1
ENST00000309188.6
ENST00000521807.2
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr7_-_27224842 1.40 ENST00000517402.1
homeobox A11
chr12_-_123187890 1.39 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr16_-_4323015 1.33 ENST00000204517.6
transcription factor AP-4 (activating enhancer binding protein 4)
chrX_-_80457385 1.30 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
high mobility group nucleosome binding domain 5
chr1_+_150954493 1.29 ENST00000368947.4
annexin A9
chr4_+_77870856 1.29 ENST00000264893.6
ENST00000502584.1
ENST00000510641.1
septin 11
chr11_-_128737163 1.28 ENST00000324003.3
ENST00000392665.2
potassium inwardly-rectifying channel, subfamily J, member 1
chr11_-_128737259 1.28 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
potassium inwardly-rectifying channel, subfamily J, member 1
chr5_-_35230771 1.27 ENST00000342362.5
prolactin receptor
chr5_+_52083730 1.22 ENST00000282588.6
ENST00000274311.2
integrin, alpha 1
pelota homolog (Drosophila)
chr1_+_53480598 1.22 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chrX_+_13587712 1.22 ENST00000361306.1
ENST00000380602.3
EGF-like-domain, multiple 6
chr7_-_27224795 1.22 ENST00000006015.3
homeobox A11
chr1_-_110155671 1.21 ENST00000351050.3
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chrX_-_133792480 1.17 ENST00000359237.4
placenta-specific 1
chr15_-_88799948 1.16 ENST00000394480.2
neurotrophic tyrosine kinase, receptor, type 3
chr1_-_23857698 1.15 ENST00000361729.2
E2F transcription factor 2
chr7_-_115670792 1.12 ENST00000265440.7
ENST00000393485.1
transcription factor EC
chr17_-_10372875 1.07 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chrX_-_55024967 1.05 ENST00000545676.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr15_-_88799384 1.05 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
neurotrophic tyrosine kinase, receptor, type 3
chr4_-_164534657 1.04 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr5_-_158757895 1.01 ENST00000231228.2
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chrX_-_151619746 1.00 ENST00000370314.4
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr1_-_44497118 0.98 ENST00000537678.1
ENST00000466926.1
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_-_58652788 0.97 ENST00000405755.2
phosphodiesterase 4D, cAMP-specific
chr7_-_56101826 0.97 ENST00000421626.1
phosphoserine phosphatase
chr7_-_115670804 0.97 ENST00000320239.7
transcription factor EC
chr18_+_29027696 0.96 ENST00000257189.4
desmoglein 3
chr4_-_38858428 0.96 ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
ENST00000506146.1
toll-like receptor 6
toll-like receptor 1
chr5_+_169780485 0.91 ENST00000377360.4
Kv channel interacting protein 1
chr1_-_44497024 0.89 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr3_+_138067521 0.88 ENST00000494949.1
muscle RAS oncogene homolog
chr12_-_123201337 0.86 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr19_+_11350278 0.83 ENST00000252453.8
chromosome 19 open reading frame 80
chr3_+_138067314 0.82 ENST00000423968.2
muscle RAS oncogene homolog
chr17_-_41277467 0.82 ENST00000494123.1
ENST00000346315.3
ENST00000309486.4
ENST00000468300.1
ENST00000354071.3
ENST00000352993.3
ENST00000471181.2
breast cancer 1, early onset
chr19_-_51869592 0.79 ENST00000596253.1
ENST00000309244.4
electron-transfer-flavoprotein, beta polypeptide
chr9_-_95055956 0.78 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
isoleucyl-tRNA synthetase
chr2_-_219031709 0.78 ENST00000295683.2
chemokine (C-X-C motif) receptor 1
chr1_+_153232160 0.75 ENST00000368742.3
loricrin
chrX_+_99839799 0.73 ENST00000373031.4
tenomodulin
chr15_-_88799661 0.69 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr10_+_101542462 0.68 ENST00000370449.4
ENST00000370434.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr16_+_56970567 0.66 ENST00000563911.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chrX_-_32173579 0.64 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
dystrophin
chr8_-_38008783 0.64 ENST00000276449.4
steroidogenic acute regulatory protein
chr6_+_31939608 0.64 ENST00000375331.2
ENST00000375333.2
serine/threonine kinase 19
chr3_+_6902794 0.63 ENST00000357716.4
ENST00000486284.1
ENST00000389336.4
ENST00000403881.1
ENST00000402647.2
glutamate receptor, metabotropic 7
chr1_+_25757376 0.62 ENST00000399766.3
ENST00000399763.3
ENST00000374343.4
transmembrane protein 57
chr22_-_39640756 0.57 ENST00000331163.6
platelet-derived growth factor beta polypeptide
chr2_+_46769798 0.49 ENST00000238738.4
ras homolog family member Q
chr2_+_169926047 0.44 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr13_-_99667960 0.43 ENST00000448493.2
dedicator of cytokinesis 9
chr3_-_99833333 0.43 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
filamin A interacting protein 1-like
chr17_-_41277370 0.40 ENST00000476777.1
ENST00000491747.2
ENST00000478531.1
ENST00000477152.1
ENST00000357654.3
ENST00000493795.1
ENST00000493919.1
breast cancer 1, early onset
chr16_+_3162557 0.37 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
zinc finger protein 205
chrX_+_115567767 0.37 ENST00000371900.4
solute carrier family 6 (amino acid transporter), member 14
chr19_-_44124019 0.36 ENST00000300811.3
zinc finger protein 428
chr18_+_46065393 0.35 ENST00000256413.3
CBP80/20-dependent translation initiation factor
chr16_+_56965960 0.33 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr17_-_76836729 0.32 ENST00000587783.1
ENST00000542802.3
ENST00000586531.1
ENST00000589424.1
ENST00000590546.2
ubiquitin specific peptidase 36
chr11_-_12030905 0.32 ENST00000326932.4
dickkopf WNT signaling pathway inhibitor 3
chr19_-_33360647 0.31 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr17_+_56315936 0.27 ENST00000543544.1
lactoperoxidase
chr7_-_99006443 0.26 ENST00000350498.3
PDGFA associated protein 1
chr10_-_101190202 0.25 ENST00000543866.1
ENST00000370508.5
glutamic-oxaloacetic transaminase 1, soluble
chr11_+_7506713 0.22 ENST00000329293.3
ENST00000534244.1
olfactomedin-like 1
chr15_+_71145578 0.22 ENST00000544974.2
ENST00000558546.1
leucine rich repeat containing 49
chr17_+_44588877 0.20 ENST00000576629.1
leucine rich repeat containing 37, member A2
chr4_+_86396265 0.19 ENST00000395184.1
Rho GTPase activating protein 24
chr9_-_13175823 0.16 ENST00000545857.1
multiple PDZ domain protein
chr10_+_26727125 0.15 ENST00000376236.4
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr22_-_30901637 0.15 ENST00000381982.3
ENST00000255858.7
ENST00000540456.1
ENST00000392772.2
SEC14-like 4 (S. cerevisiae)
chr11_-_8680383 0.15 ENST00000299550.6
tripartite motif containing 66
chr11_-_12030629 0.13 ENST00000396505.2
dickkopf WNT signaling pathway inhibitor 3
chr19_+_44455368 0.12 ENST00000591168.1
ENST00000587682.1
ENST00000251269.5
zinc finger protein 221
chr17_-_76836963 0.09 ENST00000312010.6
ubiquitin specific peptidase 36
chr20_+_8112824 0.07 ENST00000378641.3
phospholipase C, beta 1 (phosphoinositide-specific)
chr13_-_30169807 0.06 ENST00000380752.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr13_+_27825446 0.04 ENST00000311549.6
ribosomal protein L21
chr12_+_57914742 0.04 ENST00000551351.1
methyl-CpG binding domain protein 6
chr1_+_29213678 0.04 ENST00000347529.3
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 33.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
4.6 13.8 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
3.7 11.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
3.5 14.1 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
3.0 9.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
2.4 12.0 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
2.4 11.9 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
2.3 11.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
2.1 6.2 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
2.0 6.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.8 7.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
1.8 5.3 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
1.7 5.1 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
1.6 4.7 GO:0006982 response to lipid hydroperoxide(GO:0006982)
1.5 4.6 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.4 4.1 GO:0015920 leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
1.2 7.0 GO:0034201 response to oleic acid(GO:0034201)
1.1 3.4 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
1.0 4.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
1.0 2.9 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.9 7.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.9 5.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.9 5.5 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.9 2.7 GO:0035606 induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.9 9.0 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.8 2.5 GO:0001928 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.8 2.5 GO:0006711 estrogen catabolic process(GO:0006711)
0.8 4.7 GO:0051012 microtubule sliding(GO:0051012)
0.7 2.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.7 2.8 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.7 15.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.7 4.2 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.7 0.7 GO:0050787 detoxification of mercury ion(GO:0050787)
0.7 13.5 GO:0097186 amelogenesis(GO:0097186)
0.7 5.9 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.6 1.9 GO:0061386 soft palate development(GO:0060023) closure of optic fissure(GO:0061386)
0.6 1.9 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.6 2.3 GO:0009956 radial pattern formation(GO:0009956)
0.6 2.3 GO:0034436 glycoprotein transport(GO:0034436)
0.5 16.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.5 1.6 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.5 1.6 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.5 2.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.5 8.5 GO:2000194 regulation of female gonad development(GO:2000194)
0.5 6.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.5 1.9 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 1.4 GO:0046066 dGDP metabolic process(GO:0046066)
0.4 2.2 GO:0060356 leucine import(GO:0060356)
0.4 3.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4 4.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 2.3 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.4 3.7 GO:0071550 death-inducing signaling complex assembly(GO:0071550) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.4 1.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.4 1.8 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 5.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.3 1.0 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3 3.8 GO:0099563 modification of synaptic structure(GO:0099563)
0.3 1.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3 1.5 GO:0060266 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 6.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 2.1 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.3 2.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 0.8 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.3 0.8 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.2 3.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 1.2 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2 3.5 GO:0006449 regulation of translational termination(GO:0006449)
0.2 1.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 7.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.2 0.6 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.2 8.5 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.2 1.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.2 1.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 2.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.2 0.7 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 2.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.2 2.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 1.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.2 0.3 GO:0015811 L-cystine transport(GO:0015811)
0.2 0.9 GO:0001554 luteolysis(GO:0001554)
0.1 3.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.6 GO:0090677 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 21.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.4 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1 1.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 2.1 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.6 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 4.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922) positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.4 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 1.0 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 1.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.5 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 3.5 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 2.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 1.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 1.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.5 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 1.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 2.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 3.4 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 1.8 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 2.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 1.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 2.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 3.1 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 33.5 GO:0070552 BRISC complex(GO:0070552)
3.4 10.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.9 5.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.8 23.6 GO:0005577 fibrinogen complex(GO:0005577)
1.2 4.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.9 11.4 GO:0043203 axon hillock(GO:0043203)
0.9 6.6 GO:0097452 GAIT complex(GO:0097452)
0.5 9.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.5 4.4 GO:0071953 elastic fiber(GO:0071953)
0.4 1.2 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.3 5.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 1.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 1.2 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.3 1.6 GO:0043227 membrane-bounded organelle(GO:0043227)
0.2 2.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 3.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 1.0 GO:1990037 Lewy body core(GO:1990037)
0.2 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.9 GO:0005915 zonula adherens(GO:0005915)
0.1 7.0 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 6.6 GO:0031904 endosome lumen(GO:0031904)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.1 2.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 18.9 GO:0072562 blood microparticle(GO:0072562)
0.1 15.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.6 GO:0030061 mitochondrial crista(GO:0030061)
0.1 8.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.6 GO:0016013 syntrophin complex(GO:0016013)
0.1 11.5 GO:0032993 protein-DNA complex(GO:0032993)
0.1 11.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 0.8 GO:0001533 cornified envelope(GO:0001533)
0.1 4.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 3.1 GO:0035580 specific granule lumen(GO:0035580)
0.0 3.6 GO:0005902 microvillus(GO:0005902)
0.0 1.1 GO:0032982 myosin filament(GO:0032982)
0.0 6.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 2.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 3.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 6.9 GO:0043235 receptor complex(GO:0043235)
0.0 8.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 7.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 11.7 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.6 GO:0044306 neuron projection terminus(GO:0044306)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 6.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.0 GO:0005901 caveola(GO:0005901)
0.0 3.6 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 27.3 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 33.5 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
3.7 11.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
3.4 13.5 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
3.0 9.1 GO:0016662 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
2.4 12.0 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
2.4 7.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.3 7.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
2.1 10.3 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.9 13.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
1.8 9.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.8 5.3 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
1.7 5.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.6 6.2 GO:0016841 ammonia-lyase activity(GO:0016841)
1.5 11.9 GO:0001849 complement component C1q binding(GO:0001849)
1.4 5.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.1 5.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.8 3.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.8 14.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.8 4.6 GO:0030492 hemoglobin binding(GO:0030492)
0.7 3.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.7 2.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.7 4.2 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.7 2.7 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.7 2.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.6 3.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.6 4.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.6 2.3 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
0.5 2.8 GO:0050692 DBD domain binding(GO:0050692)
0.5 2.3 GO:0030151 molybdenum ion binding(GO:0030151)
0.4 2.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 4.7 GO:0008430 selenium binding(GO:0008430)
0.4 1.2 GO:0070538 oleic acid binding(GO:0070538)
0.4 5.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.4 1.6 GO:0032810 sterol response element binding(GO:0032810)
0.4 0.8 GO:0019959 interleukin-8 binding(GO:0019959)
0.4 9.8 GO:0001848 complement binding(GO:0001848)
0.4 2.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.3 1.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 0.6 GO:0070905 serine binding(GO:0070905)
0.3 4.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 0.8 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 1.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 13.8 GO:0016504 peptidase activator activity(GO:0016504)
0.2 2.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 2.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.2 1.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 3.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 2.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 2.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 3.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 0.5 GO:0032427 GBD domain binding(GO:0032427)
0.1 1.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.0 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 12.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 9.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 3.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 1.5 GO:0048273 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 12.1 GO:0005179 hormone activity(GO:0005179)
0.1 2.6 GO:0008301 DNA binding, bending(GO:0008301)
0.1 3.8 GO:0050699 WW domain binding(GO:0050699)
0.1 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 1.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 5.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 6.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.3 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.3 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 1.6 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.0 0.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 4.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 2.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 6.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 5.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 2.5 GO:0019003 GDP binding(GO:0019003)
0.0 1.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 22.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 4.7 GO:0008017 microtubule binding(GO:0008017)
0.0 1.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 4.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 5.2 GO:0003682 chromatin binding(GO:0003682)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.5 13.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 16.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 14.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 7.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 11.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 2.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 7.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.8 PID INSULIN PATHWAY Insulin Pathway
0.1 1.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 5.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 2.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 2.3 PID REELIN PATHWAY Reelin signaling pathway
0.1 4.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.0 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.9 PID SHP2 PATHWAY SHP2 signaling
0.1 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 6.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.1 PID IL1 PATHWAY IL1-mediated signaling events
0.1 0.8 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 3.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 2.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 11.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 14.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.9 21.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.8 30.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.6 12.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 7.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.5 9.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.5 19.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 11.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.4 9.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 4.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 8.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 11.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 6.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 5.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 4.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 2.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 7.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 5.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 3.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 9.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 3.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 5.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 4.1 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 3.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta