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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CEBPG

Z-value: 0.26

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Transcription factors associated with CEBPG

Gene Symbol Gene ID Gene Info
CEBPG
ENSG00000153879.4 CCAAT enhancer binding protein gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPGhg19_v2_chr19_+_33865218_33865254-0.203.7e-03Click!

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_5248294 23.09 ENST00000335295.4
HBB
hemoglobin, beta
chr3_+_186435137 16.49 ENST00000447445.1
KNG1
kininogen 1
chr3_+_186435065 14.49 ENST00000287611.2
ENST00000265023.4
KNG1
kininogen 1
chr4_+_74269956 12.80 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr3_+_186330712 11.91 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr9_+_117085336 10.38 ENST00000259396.8
ENST00000538816.1
ORM1
orosomucoid 1
chr6_+_31895467 9.19 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr9_+_117092149 9.17 ENST00000431067.2
ENST00000412657.1
ORM2
orosomucoid 2
chr9_+_130911770 8.97 ENST00000372998.1
LCN2
lipocalin 2
chr9_+_130911723 8.06 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr2_-_21266935 7.71 ENST00000233242.1
APOB
apolipoprotein B
chr16_+_72088376 7.14 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr19_-_6720686 6.72 ENST00000245907.6
C3
complement component 3
chr17_-_64225508 6.44 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr6_+_31895480 6.04 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr19_-_40971667 5.96 ENST00000263368.4
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr13_-_46679185 5.96 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr8_-_6837602 5.93 ENST00000382692.2
DEFA1
defensin, alpha 1
chr13_-_46679144 5.87 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr2_-_216300784 5.79 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr11_+_18287801 5.43 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr11_-_18270182 5.17 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr12_-_12491608 5.12 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr11_+_18287721 5.01 ENST00000356524.4
SAA1
serum amyloid A1
chr6_+_31895254 4.85 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr3_+_157154578 4.62 ENST00000295927.3
PTX3
pentraxin 3, long
chr12_-_96390063 4.55 ENST00000541929.1
HAL
histidine ammonia-lyase
chr11_-_18258342 4.54 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr7_+_22766766 4.42 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr1_-_153321301 4.37 ENST00000368739.3
PGLYRP4
peptidoglycan recognition protein 4
chr3_-_49726486 4.31 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr4_+_71248795 3.99 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chrX_+_138612889 3.93 ENST00000218099.2
ENST00000394090.2
F9
coagulation factor IX
chr2_-_112614424 3.92 ENST00000427997.1
ANAPC1
anaphase promoting complex subunit 1
chr1_+_111770232 3.63 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr1_+_111770278 3.55 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chrX_+_46937745 3.54 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr6_-_135271260 3.54 ENST00000265605.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr1_+_245133278 3.50 ENST00000366522.2
EFCAB2
EF-hand calcium binding domain 2
chr6_-_135271219 3.29 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr3_-_194072019 3.22 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr1_-_47655686 3.17 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr14_-_70263979 3.13 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr1_-_161277210 3.13 ENST00000491222.2
MPZ
myelin protein zero
chr8_-_121824374 3.06 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr4_+_71226468 2.99 ENST00000226460.4
SMR3A
submaxillary gland androgen regulated protein 3A
chr11_-_124806297 2.94 ENST00000298251.4
HEPACAM
hepatic and glial cell adhesion molecule
chr8_-_6795823 2.92 ENST00000297435.2
DEFA4
defensin, alpha 4, corticostatin
chr22_-_30901637 2.90 ENST00000381982.3
ENST00000255858.7
ENST00000540456.1
ENST00000392772.2
SEC14L4
SEC14-like 4 (S. cerevisiae)
chr12_+_57522258 2.89 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr3_-_158390282 2.73 ENST00000264265.3
LXN
latexin
chr12_-_96390108 2.73 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr1_+_196743912 2.65 ENST00000367425.4
CFHR3
complement factor H-related 3
chr14_-_80677815 2.64 ENST00000557125.1
ENST00000555750.1
DIO2
deiodinase, iodothyronine, type II
chr3_+_178253993 2.37 ENST00000420517.2
ENST00000452583.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr3_-_148939835 2.37 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr12_-_114841703 2.32 ENST00000526441.1
TBX5
T-box 5
chr2_+_102721023 2.29 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr5_+_49963239 2.22 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr11_+_59824060 2.17 ENST00000395032.2
ENST00000358152.2
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr1_+_196743943 2.16 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr14_+_96000930 1.95 ENST00000331334.4
GLRX5
glutaredoxin 5
chrX_-_135333722 1.94 ENST00000316077.9
MAP7D3
MAP7 domain containing 3
chr5_-_121413974 1.93 ENST00000231004.4
LOX
lysyl oxidase
chrX_+_49644470 1.87 ENST00000508866.2
USP27X
ubiquitin specific peptidase 27, X-linked
chr11_+_59824127 1.84 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr4_+_175839506 1.82 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM29
ADAM metallopeptidase domain 29
chr5_-_146258205 1.61 ENST00000394413.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr6_-_133055815 1.60 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr17_-_39769005 1.58 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr9_+_115913222 1.57 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr12_-_53074182 1.56 ENST00000252244.3
KRT1
keratin 1
chr5_+_36152179 1.52 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr11_-_33913708 1.51 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr4_+_175839551 1.50 ENST00000404450.4
ENST00000514159.1
ADAM29
ADAM metallopeptidase domain 29
chr4_-_119274121 1.47 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr19_+_55417499 1.47 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
NCR1
natural cytotoxicity triggering receptor 1
chr12_-_71551868 1.35 ENST00000247829.3
TSPAN8
tetraspanin 8
chr19_+_55417530 1.33 ENST00000350790.5
ENST00000338835.5
ENST00000357397.5
NCR1
natural cytotoxicity triggering receptor 1
chr9_+_136399929 1.32 ENST00000393060.1
ADAMTSL2
ADAMTS-like 2
chr4_-_10023095 1.31 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr5_+_49962772 1.29 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr8_+_42552533 1.22 ENST00000289957.2
CHRNB3
cholinergic receptor, nicotinic, beta 3 (neuronal)
chr3_+_40498783 1.19 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
RPL14
ribosomal protein L14
chr21_-_37852359 1.16 ENST00000399137.1
ENST00000399135.1
CLDN14
claudin 14
chr8_+_97597148 1.15 ENST00000521590.1
SDC2
syndecan 2
chr14_+_21387508 1.15 ENST00000555624.1
RP11-84C10.2
RP11-84C10.2
chr13_-_36788718 1.09 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr3_+_73110810 1.07 ENST00000533473.1
EBLN2
endogenous Bornavirus-like nucleoprotein 2
chr1_+_158901329 0.99 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr4_+_70796784 0.97 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr1_+_172389821 0.96 ENST00000367727.4
C1orf105
chromosome 1 open reading frame 105
chr2_-_32390801 0.96 ENST00000608489.1
RP11-563N4.1
RP11-563N4.1
chr19_+_47538560 0.96 ENST00000439365.2
ENST00000594670.1
NPAS1
neuronal PAS domain protein 1
chr1_+_245133062 0.93 ENST00000366523.1
EFCAB2
EF-hand calcium binding domain 2
chr18_+_33767473 0.92 ENST00000261326.5
MOCOS
molybdenum cofactor sulfurase
chr10_-_70092635 0.90 ENST00000309049.4
PBLD
phenazine biosynthesis-like protein domain containing
chr10_-_92681033 0.88 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr16_+_33020496 0.88 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr11_+_60048053 0.86 ENST00000337908.4
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr19_+_49258775 0.86 ENST00000593756.1
FGF21
fibroblast growth factor 21
chr15_-_34628951 0.81 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr21_+_38792602 0.75 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr6_-_27799305 0.69 ENST00000357549.2
HIST1H4K
histone cluster 1, H4k
chr4_-_70826725 0.69 ENST00000353151.3
CSN2
casein beta
chr6_-_133055896 0.66 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr13_-_72441315 0.65 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr11_-_102668879 0.64 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr21_+_43619796 0.63 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr2_-_89310012 0.63 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr1_+_154377669 0.61 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr19_+_2476116 0.60 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr20_-_48782639 0.58 ENST00000435301.2
RP11-112L6.3
RP11-112L6.3
chr1_-_179112189 0.57 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr7_-_83824169 0.56 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_-_323689 0.56 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr11_+_60048129 0.56 ENST00000355131.3
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr19_+_49259325 0.54 ENST00000222157.3
FGF21
fibroblast growth factor 21
chr14_-_80677970 0.53 ENST00000438257.4
DIO2
deiodinase, iodothyronine, type II
chr11_-_72504637 0.52 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_+_6887571 0.51 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr12_-_57522813 0.51 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr17_-_3182268 0.48 ENST00000408891.2
OR3A2
olfactory receptor, family 3, subfamily A, member 2
chr7_-_8276508 0.39 ENST00000401396.1
ENST00000317367.5
ICA1
islet cell autoantigen 1, 69kDa
chr12_-_8693539 0.35 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr22_-_30867973 0.34 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr20_+_54987168 0.31 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr12_-_71551652 0.30 ENST00000546561.1
TSPAN8
tetraspanin 8
chr20_+_361261 0.29 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr17_-_42200958 0.24 ENST00000336057.5
HDAC5
histone deacetylase 5
chr20_+_54987305 0.22 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr6_-_30710265 0.20 ENST00000438162.1
ENST00000454845.1
FLOT1
flotillin 1
chr14_+_21387491 0.14 ENST00000258817.2
RP11-84C10.2
RP11-84C10.2
chr4_+_71600144 0.13 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr6_-_132939317 0.11 ENST00000275191.2
TAAR2
trace amine associated receptor 2
chr5_-_135701164 0.09 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr1_-_179112173 0.07 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 23.1 GO:0030185 nitric oxide transport(GO:0030185)
4.3 12.8 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
3.4 17.0 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
3.0 11.8 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.4 19.6 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
2.4 7.3 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
2.4 7.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
2.2 6.7 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
2.0 5.9 GO:0035915 pore formation in membrane of other organism(GO:0035915)
1.9 5.8 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
1.8 41.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.7 5.0 GO:0002384 hepatic immune response(GO:0002384)
1.5 4.4 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.2 3.5 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
1.1 7.7 GO:0006642 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269)
1.0 10.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.0 2.9 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.9 4.6 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.8 2.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.8 2.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.7 7.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.6 6.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.5 11.9 GO:0030502 pinocytosis(GO:0006907) negative regulation of bone mineralization(GO:0030502)
0.4 9.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 6.0 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.4 1.4 GO:1904640 response to methionine(GO:1904640)
0.3 2.9 GO:0019732 antifungal humoral response(GO:0019732)
0.3 20.1 GO:0006953 acute-phase response(GO:0006953)
0.3 4.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 3.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 0.7 GO:1903487 regulation of lactation(GO:1903487)
0.2 0.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 2.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.6 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.2 2.0 GO:0009249 protein lipoylation(GO:0009249)
0.2 1.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 1.2 GO:0008218 bioluminescence(GO:0008218)
0.2 1.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.2 0.8 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 1.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 2.4 GO:0006825 copper ion transport(GO:0006825)
0.1 0.5 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 2.7 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 2.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 3.1 GO:0098743 cell aggregation(GO:0098743)
0.1 0.9 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 0.6 GO:0048880 sensory system development(GO:0048880)
0.1 1.6 GO:0051546 keratinocyte migration(GO:0051546)
0.1 1.3 GO:0046415 urate metabolic process(GO:0046415)
0.1 3.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 2.8 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.1 3.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.5 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 1.9 GO:0071108 protein K63-linked deubiquitination(GO:0070536) protein K48-linked deubiquitination(GO:0071108)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.0 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.8 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.6 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.6 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 1.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.9 GO:0046785 microtubule polymerization(GO:0046785)
0.0 2.7 GO:0006956 complement activation(GO:0006956)
0.0 0.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 1.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.1 GO:0048477 oogenesis(GO:0048477)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 30.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.3 5.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.0 7.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.7 26.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.7 81.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 15.9 GO:0035580 specific granule lumen(GO:0035580)
0.2 33.4 GO:0072562 blood microparticle(GO:0072562)
0.1 3.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 2.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.5 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 11.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 5.1 GO:0043195 terminal bouton(GO:0043195)
0.1 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 2.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 36.0 GO:0005615 extracellular space(GO:0005615)
0.0 6.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.2 GO:0055037 recycling endosome(GO:0055037)
0.0 1.6 GO:0030425 dendrite(GO:0030425)
0.0 2.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 30.2 GO:0030492 hemoglobin binding(GO:0030492)
1.9 7.7 GO:0035473 lipase binding(GO:0035473)
1.8 7.3 GO:0016841 ammonia-lyase activity(GO:0016841)
1.5 6.0 GO:0004074 biliverdin reductase activity(GO:0004074)
1.5 4.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.3 6.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.8 12.8 GO:0015643 toxic substance binding(GO:0015643)
0.8 3.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.7 2.9 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.7 7.2 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.6 4.6 GO:0001849 complement component C1q binding(GO:0001849)
0.6 2.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.6 6.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 15.2 GO:0001848 complement binding(GO:0001848)
0.6 5.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.5 3.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.5 15.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 40.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.5 2.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 20.1 GO:0042056 chemoattractant activity(GO:0042056)
0.3 0.9 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 2.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.3 GO:0050436 microfibril binding(GO:0050436)
0.2 0.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.9 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.2 0.9 GO:0030151 molybdenum ion binding(GO:0030151)
0.2 1.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 21.4 GO:0002020 protease binding(GO:0002020)
0.1 1.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 3.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.6 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 2.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 20.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 4.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 1.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 2.8 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.8 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 1.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0003823 antigen binding(GO:0003823)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 37.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.5 15.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.4 10.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 19.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 5.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 12.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 11.9 PID BMP PATHWAY BMP receptor signaling
0.1 4.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 14.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 34.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.3 26.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.0 15.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 6.5 REACTOME DEFENSINS Genes involved in Defensins
0.4 7.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 10.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 4.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 5.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 4.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 6.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 3.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 23.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4