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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CREB3L2

Z-value: 0.73

Motif logo

Transcription factors associated with CREB3L2

Gene Symbol Gene ID Gene Info
ENSG00000182158.10 cAMP responsive element binding protein 3 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB3L2hg19_v2_chr7_-_137686791_1376868210.605.1e-23Click!

Activity profile of CREB3L2 motif

Sorted Z-values of CREB3L2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_6523688 23.92 ENST00000490996.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr8_+_22224760 22.04 ENST00000359741.5
ENST00000520644.1
ENST00000240095.6
solute carrier family 39 (zinc transporter), member 14
chr2_+_74425689 21.63 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr6_-_7911042 20.27 ENST00000379757.4
thioredoxin domain containing 5 (endoplasmic reticulum)
chr12_-_56123444 18.39 ENST00000546457.1
ENST00000549117.1
CD63 molecule
chr12_-_49318715 18.23 ENST00000444214.2
FK506 binding protein 11, 19 kDa
chr12_-_56122761 17.70 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
CD63 molecule
chr1_-_11120057 17.17 ENST00000376957.2
spermidine synthase
chr19_-_4670345 17.01 ENST00000599630.1
ENST00000262947.3
chromosome 19 open reading frame 10
chr21_-_18985158 16.53 ENST00000339775.6
BTG family, member 3
chr21_-_18985230 16.21 ENST00000457956.1
ENST00000348354.6
BTG family, member 3
chr7_-_6523755 16.15 ENST00000436575.1
ENST00000258739.4
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr2_-_10588630 15.21 ENST00000234111.4
ornithine decarboxylase 1
chr2_-_69614373 15.03 ENST00000361060.5
ENST00000357308.4
glutamine--fructose-6-phosphate transaminase 1
chr21_-_40720974 13.80 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr17_+_49243792 13.69 ENST00000393183.3
ENST00000393190.1
NME1-NME2 readthrough
chr21_-_40720995 13.67 ENST00000380749.5
high mobility group nucleosome binding domain 1
chrX_+_48433326 13.62 ENST00000376755.1
RNA binding motif (RNP1, RRM) protein 3
chr5_+_34656569 13.45 ENST00000428746.2
retinoic acid induced 14
chr8_+_82192501 13.35 ENST00000297258.6
fatty acid binding protein 5 (psoriasis-associated)
chr7_-_121036337 13.11 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
family with sequence similarity 3, member C
chr11_+_32112431 13.01 ENST00000054950.3
reticulocalbin 1, EF-hand calcium binding domain
chr1_+_46016703 12.29 ENST00000481885.1
ENST00000351829.4
ENST00000471651.1
aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr5_+_34656331 12.28 ENST00000265109.3
retinoic acid induced 14
chr3_-_57583052 12.06 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr6_-_32811771 11.74 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr12_+_57624085 11.54 ENST00000553474.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr3_+_122785895 11.52 ENST00000316218.7
protein disulfide isomerase family A, member 5
chr8_-_144679296 11.31 ENST00000317198.6
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chrX_+_48432892 11.25 ENST00000376759.3
ENST00000430348.2
RNA binding motif (RNP1, RRM) protein 3
chr6_+_13615554 11.03 ENST00000451315.2
nucleolar protein 7, 27kDa
chr3_-_57583185 10.74 ENST00000463880.1
ADP-ribosylation factor 4
chr2_+_216176540 10.68 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr5_+_112196919 10.59 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
signal recognition particle 19kDa
chr3_-_57583130 10.51 ENST00000303436.6
ADP-ribosylation factor 4
chr2_+_113403434 10.41 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chr7_+_100464760 10.35 ENST00000200457.4
thyroid hormone receptor interactor 6
chr12_+_57624119 9.87 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr2_+_216176761 9.73 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr10_-_71993176 9.48 ENST00000373232.3
pyrophosphatase (inorganic) 1
chr5_+_65440032 9.44 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr2_+_198365095 9.26 ENST00000409468.1
heat shock 10kDa protein 1
chr2_-_47143160 9.23 ENST00000409800.1
ENST00000409218.1
multiple coagulation factor deficiency 2
chr17_+_49243639 9.20 ENST00000512737.1
ENST00000503064.1
NME1-NME2 readthrough
chr10_+_89419370 9.09 ENST00000361175.4
ENST00000456849.1
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr1_+_42922173 8.95 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
phosphopantothenoylcysteine synthetase
chr12_+_57623869 8.95 ENST00000414700.3
ENST00000557703.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr3_+_148709128 8.83 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
glycogenin 1
chr5_+_122110691 8.66 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chr1_+_42921761 8.41 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chr5_-_143550159 8.40 ENST00000448443.2
ENST00000513112.1
ENST00000519064.1
ENST00000274496.5
Yip1 domain family, member 5
chr2_-_47142884 8.28 ENST00000409105.1
ENST00000409973.1
ENST00000409913.1
ENST00000319466.4
multiple coagulation factor deficiency 2
chr3_+_158519654 8.11 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr8_-_144679532 7.98 ENST00000534380.1
ENST00000533494.1
ENST00000531218.1
ENST00000526340.1
ENST00000533204.1
ENST00000532400.1
ENST00000529516.1
ENST00000534377.1
ENST00000531621.1
ENST00000530191.1
ENST00000524900.1
ENST00000526838.1
ENST00000531931.1
ENST00000534475.1
ENST00000442189.2
ENST00000524624.1
ENST00000532596.1
ENST00000529832.1
ENST00000530306.1
ENST00000530545.1
ENST00000525261.1
ENST00000534804.1
ENST00000528303.1
ENST00000528610.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr2_-_27545921 7.92 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
MpV17 mitochondrial inner membrane protein
chr20_+_44520009 7.88 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr1_+_180123969 7.78 ENST00000367602.3
ENST00000367600.5
quiescin Q6 sulfhydryl oxidase 1
chr2_-_65357225 7.61 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A, member RAS oncogene family
chr20_+_44519948 7.60 ENST00000354880.5
ENST00000191018.5
cathepsin A
chr22_-_43411106 7.60 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
protein kinase C and casein kinase substrate in neurons 2
chr2_+_172544294 7.58 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
dynein, cytoplasmic 1, intermediate chain 2
chr12_+_57623477 7.50 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr18_+_158513 7.30 ENST00000400266.3
ENST00000580410.1
ENST00000383589.2
ENST00000261601.7
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr2_+_46926048 7.17 ENST00000306503.5
suppressor of cytokine signaling 5
chr10_-_120840309 7.16 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chr17_-_39968855 7.14 ENST00000355468.3
ENST00000590496.1
leprecan-like 4
chr17_+_39969183 7.10 ENST00000321562.4
FK506 binding protein 10, 65 kDa
chr10_-_126849588 7.04 ENST00000411419.2
C-terminal binding protein 2
chr3_+_148709310 7.04 ENST00000484197.1
ENST00000492285.2
ENST00000461191.1
glycogenin 1
chr19_+_47634039 7.02 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr2_+_201676256 6.98 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
basic leucine zipper and W2 domains 1
chr4_-_83812402 6.92 ENST00000395310.2
SEC31 homolog A (S. cerevisiae)
chr19_+_36705504 6.85 ENST00000456324.1
zinc finger protein 146
chr19_-_42759300 6.65 ENST00000222329.4
Ets2 repressor factor
chr2_+_201676908 6.64 ENST00000409226.1
ENST00000452790.2
basic leucine zipper and W2 domains 1
chrX_+_131157322 6.58 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chr2_+_171785824 6.53 ENST00000452526.2
golgi reassembly stacking protein 2, 55kDa
chr9_+_117350009 6.50 ENST00000374050.3
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr4_-_83812248 6.49 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31 homolog A (S. cerevisiae)
chr5_-_143550241 6.42 ENST00000522203.1
Yip1 domain family, member 5
chr10_+_103892787 6.39 ENST00000278070.2
ENST00000413464.2
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr10_+_112257596 6.29 ENST00000369583.3
dual specificity phosphatase 5
chrX_+_131157290 6.25 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr10_-_97416400 6.24 ENST00000371224.2
ENST00000371221.3
aldehyde dehydrogenase 18 family, member A1
chr2_-_70520539 6.08 ENST00000482975.2
ENST00000438261.1
small nuclear ribonucleoprotein polypeptide G
chr11_-_62341445 6.06 ENST00000329251.4
eukaryotic translation elongation factor 1 gamma
chr12_-_76953573 5.99 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr22_-_43253189 5.89 ENST00000437119.2
ENST00000429508.2
ENST00000454099.1
ENST00000263245.5
ADP-ribosylation factor GTPase activating protein 3
chr15_-_72668805 5.86 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr10_-_71930222 5.75 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1 homolog A (S. cerevisiae)
chr11_-_118972575 5.71 ENST00000432443.2
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr6_-_43197189 5.65 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr16_-_30441293 5.65 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
dCTP pyrophosphatase 1
chr2_+_207024306 5.59 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
eukaryotic translation elongation factor 1 beta 2
chr10_+_70715884 5.56 ENST00000354185.4
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr16_+_88923494 5.43 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
trafficking protein particle complex 2-like
chr17_+_8191815 5.37 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr18_+_9913977 5.36 ENST00000400000.2
ENST00000340541.4
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr19_+_36706024 5.32 ENST00000443387.2
zinc finger protein 146
chr2_+_172544182 5.04 ENST00000409197.1
ENST00000456808.1
ENST00000409317.1
ENST00000409773.1
ENST00000411953.1
ENST00000409453.1
dynein, cytoplasmic 1, intermediate chain 2
chr6_+_31802685 4.94 ENST00000375639.2
ENST00000375638.3
ENST00000375635.2
ENST00000375642.2
ENST00000395789.1
chromosome 6 open reading frame 48
chr1_-_17380630 4.93 ENST00000375499.3
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr12_+_131356582 4.87 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN, member RAS oncogene family
chr11_-_61560053 4.78 ENST00000537328.1
transmembrane protein 258
chr6_+_32811885 4.72 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chrX_-_102941596 4.60 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
mortality factor 4 like 2
chr7_-_134143841 4.59 ENST00000285930.4
aldo-keto reductase family 1, member B1 (aldose reductase)
chr6_+_31802364 4.53 ENST00000375640.3
ENST00000375641.2
chromosome 6 open reading frame 48
chr2_+_27440229 4.49 ENST00000264705.4
ENST00000403525.1
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr7_+_16793160 4.30 ENST00000262067.4
tetraspanin 13
chr1_+_32479430 4.29 ENST00000327300.7
ENST00000492989.1
KH domain containing, RNA binding, signal transduction associated 1
chrX_+_105937068 4.23 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr6_-_144329531 4.15 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
pleiomorphic adenoma gene-like 1
chr19_-_47290535 4.13 ENST00000412532.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr15_+_89182178 4.08 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr6_+_151561506 3.92 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr1_+_116915855 3.92 ENST00000295598.5
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr6_-_32140886 3.86 ENST00000395496.1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr2_+_131100710 3.76 ENST00000452955.1
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr11_-_6502534 3.74 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ADP-ribosylation factor interacting protein 2
chr19_+_34663397 3.63 ENST00000540746.2
ENST00000544216.3
ENST00000433627.5
LSM14A, SCD6 homolog A (S. cerevisiae)
chr9_+_706842 3.54 ENST00000382293.3
KN motif and ankyrin repeat domains 1
chr1_+_44444865 3.50 ENST00000372324.1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr9_-_125667494 3.42 ENST00000335387.5
ENST00000357244.2
ENST00000373665.2
ring finger and CCCH-type domains 2
chr6_-_28891709 3.40 ENST00000377194.3
ENST00000377199.3
tripartite motif containing 27
chr2_+_217498105 3.33 ENST00000233809.4
insulin-like growth factor binding protein 2, 36kDa
chr22_-_18257178 3.29 ENST00000342111.5
BH3 interacting domain death agonist
chr2_+_201936458 3.27 ENST00000237889.4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr8_+_56014949 3.10 ENST00000327381.6
XK, Kell blood group complex subunit-related family, member 4
chr15_+_89181974 3.05 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr2_+_46926326 2.99 ENST00000394861.2
suppressor of cytokine signaling 5
chr3_+_133292759 2.97 ENST00000431519.2
CDV3 homolog (mouse)
chr1_-_153940097 2.93 ENST00000413622.1
ENST00000310483.6
solute carrier family 39 (zinc transporter), member 1
chr2_+_172543919 2.92 ENST00000452242.1
ENST00000340296.4
dynein, cytoplasmic 1, intermediate chain 2
chr5_-_150537279 2.90 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
annexin A6
chr2_+_169312725 2.87 ENST00000392687.4
ceramide synthase 6
chr2_+_172544011 2.85 ENST00000508530.1
dynein, cytoplasmic 1, intermediate chain 2
chr1_-_32801825 2.82 ENST00000329421.7
MARCKS-like 1
chr3_+_12525931 2.81 ENST00000446004.1
ENST00000314571.7
ENST00000454502.2
ENST00000383797.5
ENST00000402228.3
ENST00000284995.6
ENST00000444864.1
TSEN2 tRNA splicing endonuclease subunit
chr11_+_111957497 2.77 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
succinate dehydrogenase complex, subunit D, integral membrane protein
chr22_-_18256742 2.75 ENST00000317361.7
BH3 interacting domain death agonist
chr20_-_57607347 2.74 ENST00000395663.1
ENST00000395659.1
ENST00000243997.3
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr2_-_120980939 2.72 ENST00000426077.2
transmembrane protein 185B
chr2_+_172543967 2.70 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
dynein, cytoplasmic 1, intermediate chain 2
chr7_+_150929550 2.67 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
chondroitin polymerizing factor 2
chr18_+_9708162 2.66 ENST00000578921.1
RAB31, member RAS oncogene family
chr12_+_6833437 2.44 ENST00000534947.1
ENST00000541866.1
ENST00000534877.1
ENST00000538753.1
COP9 signalosome subunit 7A
chr22_+_38864041 2.42 ENST00000216014.4
ENST00000409006.3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr2_-_27341765 2.25 ENST00000405600.1
cell growth regulator with EF-hand domain 1
chr1_-_45956800 2.21 ENST00000538496.1
testis-specific kinase 2
chr1_-_1167411 2.19 ENST00000263741.7
stromal cell derived factor 4
chr3_+_45636219 2.14 ENST00000273317.4
LIM domains containing 1
chr1_+_231376941 2.12 ENST00000436239.1
ENST00000366647.4
ENST00000366646.3
ENST00000416000.1
glyceronephosphate O-acyltransferase
chr12_+_6833237 2.12 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COP9 signalosome subunit 7A
chr22_-_18257249 2.10 ENST00000399765.1
ENST00000399767.1
ENST00000399774.3
BH3 interacting domain death agonist
chr21_+_37442239 2.05 ENST00000530908.1
ENST00000290349.6
ENST00000439427.2
ENST00000399191.3
carbonyl reductase 1
chr8_-_99129338 1.96 ENST00000520507.1
heat-responsive protein 12
chr19_+_34663551 1.87 ENST00000586157.1
LSM14A, SCD6 homolog A (S. cerevisiae)
chr17_+_65821780 1.81 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
bromodomain PHD finger transcription factor
chr14_-_106174960 1.79 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr3_-_155572164 1.72 ENST00000392845.3
ENST00000359479.3
solute carrier family 33 (acetyl-CoA transporter), member 1
chr11_-_111957451 1.71 ENST00000504148.2
ENST00000541231.1
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr12_-_93836028 1.68 ENST00000318066.2
ubiquitin-conjugating enzyme E2N
chr5_+_43603229 1.68 ENST00000344920.4
ENST00000512996.2
nicotinamide nucleotide transhydrogenase
chr12_-_93835665 1.65 ENST00000552442.1
ENST00000550657.1
ubiquitin-conjugating enzyme E2N
chr8_+_1772132 1.64 ENST00000349830.3
ENST00000520359.1
ENST00000518288.1
ENST00000398560.1
Rho guanine nucleotide exchange factor (GEF) 10
chr2_+_169312350 1.59 ENST00000305747.6
ceramide synthase 6
chr15_+_75315896 1.46 ENST00000342932.3
ENST00000564923.1
ENST00000569562.1
ENST00000568649.1
phosphopantothenoylcysteine decarboxylase
chr20_+_25228669 1.39 ENST00000216962.4
phosphorylase, glycogen; brain
chr14_+_101193164 1.38 ENST00000341267.4
delta-like 1 homolog (Drosophila)
chr6_+_151561085 1.36 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr3_-_123603137 1.31 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
myosin light chain kinase
chr20_-_33413416 1.31 ENST00000359003.2
nuclear receptor coactivator 6
chr15_-_72668185 1.30 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chr11_-_6502580 1.28 ENST00000423813.2
ENST00000396777.3
ADP-ribosylation factor interacting protein 2
chr4_-_186347099 1.24 ENST00000505357.1
ENST00000264689.6
UFM1-specific peptidase 2
chr12_+_67663056 1.24 ENST00000545606.1
cullin-associated and neddylation-dissociated 1
chr12_-_104531945 1.23 ENST00000551446.1
nuclear transcription factor Y, beta
chr9_-_125667618 1.15 ENST00000423239.2
ring finger and CCCH-type domains 2
chr2_-_27341966 1.00 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
cell growth regulator with EF-hand domain 1
chr19_-_44143939 0.99 ENST00000222374.2
cell adhesion molecule 4
chr20_+_61584026 0.92 ENST00000370351.4
ENST00000370349.3
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr12_-_6716534 0.91 ENST00000544484.1
ENST00000309577.6
ENST00000357008.2
chromodomain helicase DNA binding protein 4
chr2_-_27341872 0.85 ENST00000312734.4
cell growth regulator with EF-hand domain 1
chr15_+_58724184 0.85 ENST00000433326.2
lipase, hepatic
chr14_-_106054659 0.84 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_-_29663954 0.79 ENST00000216085.7
rhomboid domain containing 3
chr1_-_113498943 0.75 ENST00000369626.3
solute carrier family 16 (monocarboxylate transporter), member 1
chr12_-_6716569 0.75 ENST00000544040.1
ENST00000545942.1
chromodomain helicase DNA binding protein 4
chr13_+_98794810 0.74 ENST00000595437.1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr9_+_130565487 0.70 ENST00000373225.3
ENST00000431857.1
folylpolyglutamate synthase
chr17_+_80477571 0.69 ENST00000335255.5
forkhead box K2
chr7_-_100808843 0.68 ENST00000249330.2
VGF nerve growth factor inducible
chr12_+_121416437 0.62 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1 homeobox A
chr21_+_44394742 0.56 ENST00000432907.2
PBX/knotted 1 homeobox 1
chr19_+_10812108 0.48 ENST00000250237.5
ENST00000592254.1
queuine tRNA-ribosyltransferase 1
chr5_-_114880533 0.43 ENST00000274457.3
fem-1 homolog c (C. elegans)
chr19_+_49458107 0.41 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr17_-_2169425 0.39 ENST00000570606.1
ENST00000354901.4
SMG6 nonsense mediated mRNA decay factor
chr20_-_17662878 0.37 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
ribosome binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 37.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
5.1 20.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
4.1 12.3 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
3.8 15.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
3.8 41.5 GO:0006621 protein retention in ER lumen(GO:0006621)
3.5 10.6 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
3.2 9.5 GO:0071344 diphosphate metabolic process(GO:0071344)
3.0 33.3 GO:0031584 activation of phospholipase D activity(GO:0031584) apical protein localization(GO:0045176)
2.8 36.1 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
2.5 17.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
2.4 7.2 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
2.4 7.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
2.3 9.1 GO:0000103 sulfate assimilation(GO:0000103)
2.2 22.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
2.1 10.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
2.1 6.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.9 21.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.8 5.4 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
1.7 15.5 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
1.7 10.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.6 4.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.5 4.6 GO:0006059 hexitol metabolic process(GO:0006059) response to methylglyoxal(GO:0051595)
1.5 4.6 GO:0061470 T follicular helper cell differentiation(GO:0061470)
1.5 4.5 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.3 5.4 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
1.3 26.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
1.2 3.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.1 5.7 GO:0019348 dolichol metabolic process(GO:0019348)
1.1 14.8 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
1.1 5.7 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
1.1 15.0 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
1.1 4.3 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
1.0 10.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.0 6.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.0 4.1 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.9 27.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.9 2.8 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.9 2.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.9 18.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.9 6.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.8 8.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.8 7.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.8 7.6 GO:0070836 caveola assembly(GO:0070836)
0.7 2.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.7 4.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.7 3.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.6 8.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.6 3.9 GO:0090032 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.5 7.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.5 4.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.5 9.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.5 39.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.4 16.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.4 5.5 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.4 0.4 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.4 18.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 6.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.4 4.9 GO:0006105 succinate metabolic process(GO:0006105)
0.4 6.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.4 2.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.4 5.7 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.4 5.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.7 GO:0051182 coenzyme transport(GO:0051182)
0.3 1.7 GO:0006740 NADPH regeneration(GO:0006740)
0.3 4.6 GO:0000338 protein deneddylation(GO:0000338)
0.3 2.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 14.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.3 1.7 GO:0072553 terminal button organization(GO:0072553)
0.3 3.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 7.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 3.3 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.2 5.0 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 30.9 GO:0006414 translational elongation(GO:0006414)
0.2 2.0 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 0.8 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.2 6.1 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.2 0.6 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.2 10.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 0.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 16.5 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.2 1.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 4.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 2.2 GO:0009650 UV protection(GO:0009650)
0.1 1.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 5.6 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 3.3 GO:0010226 response to lithium ion(GO:0010226)
0.1 16.9 GO:0045727 positive regulation of translation(GO:0045727)
0.1 2.8 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.1 2.9 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 1.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 30.8 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.1 4.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 2.2 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 4.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 2.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.4 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 7.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 2.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 2.7 GO:0090382 phagosome maturation(GO:0090382)
0.1 3.0 GO:0008283 cell proliferation(GO:0008283)
0.1 5.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 3.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.1 6.5 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.7 GO:0002021 response to dietary excess(GO:0002021)
0.0 13.7 GO:0001701 in utero embryonic development(GO:0001701)
0.0 4.3 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 1.2 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 4.2 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 2.9 GO:0006364 rRNA processing(GO:0006364)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 37.8 GO:0070552 BRISC complex(GO:0070552)
3.0 36.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
2.5 24.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
2.2 15.5 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
2.1 10.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
2.1 16.5 GO:1990111 spermatoproteasome complex(GO:1990111)
1.9 7.7 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.8 7.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.4 8.7 GO:0030905 retromer, tubulation complex(GO:0030905)
1.3 10.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
1.2 33.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.1 4.6 GO:0097454 Schwann cell microvillus(GO:0097454)
1.1 3.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.9 2.6 GO:0071751 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.8 7.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.8 6.1 GO:0005683 U7 snRNP(GO:0005683)
0.8 3.8 GO:0034457 Mpp10 complex(GO:0034457)
0.7 13.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.7 21.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.7 2.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.6 34.7 GO:0005801 cis-Golgi network(GO:0005801)
0.5 7.0 GO:0097470 ribbon synapse(GO:0097470)
0.5 5.4 GO:0030008 TRAPP complex(GO:0030008)
0.4 4.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 2.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.3 4.9 GO:0090543 Flemming body(GO:0090543)
0.3 44.4 GO:0032587 ruffle membrane(GO:0032587)
0.3 6.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.3 1.8 GO:0016589 NURF complex(GO:0016589)
0.3 26.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 2.2 GO:0032059 bleb(GO:0032059)
0.2 7.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 3.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 2.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 7.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 3.4 GO:0030904 retromer complex(GO:0030904)
0.2 24.9 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 17.6 GO:0043202 lysosomal lumen(GO:0043202)
0.1 8.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 2.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 8.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 4.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 4.6 GO:0008180 COP9 signalosome(GO:0008180)
0.1 14.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 7.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 5.6 GO:0015030 Cajal body(GO:0015030)
0.1 5.4 GO:0014704 intercalated disc(GO:0014704)
0.1 10.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 11.1 GO:0001650 fibrillar center(GO:0001650)
0.1 7.3 GO:0000502 proteasome complex(GO:0000502)
0.1 1.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 4.5 GO:0043195 terminal bouton(GO:0043195)
0.1 3.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.7 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 6.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 9.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 9.3 GO:0030027 lamellipodium(GO:0030027)
0.0 12.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 15.0 GO:0000785 chromatin(GO:0000785)
0.0 0.7 GO:0030175 filopodium(GO:0030175)
0.0 5.3 GO:0005925 focal adhesion(GO:0005925)
0.0 4.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 30.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0005741 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 1.6 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 10.4 GO:0005730 nucleolus(GO:0005730)
0.0 1.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 2.6 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
10.0 40.1 GO:0005046 KDEL sequence binding(GO:0005046)
7.2 21.6 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
6.8 20.4 GO:0019238 cyclohydrolase activity(GO:0019238)
5.7 17.2 GO:0004766 spermidine synthase activity(GO:0004766)
5.4 37.8 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
4.0 15.9 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
3.1 22.0 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
3.0 9.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
2.6 10.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
2.6 7.7 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
2.4 7.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
2.4 9.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
2.1 6.2 GO:0008859 exoribonuclease II activity(GO:0008859)
1.9 7.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
1.9 15.5 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
1.9 5.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.9 16.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.8 5.4 GO:0033149 FFAT motif binding(GO:0033149)
1.7 8.7 GO:1990460 leptin receptor binding(GO:1990460)
1.6 30.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.6 6.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
1.5 4.5 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.3 33.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.3 3.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
1.2 10.6 GO:0008312 7S RNA binding(GO:0008312)
1.2 7.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
1.1 30.9 GO:0003746 translation elongation factor activity(GO:0003746)
1.1 6.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.0 7.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.0 19.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.9 2.8 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.9 7.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.9 2.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.9 25.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.8 17.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.8 5.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.7 4.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.7 5.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.7 15.0 GO:0008483 transaminase activity(GO:0008483)
0.6 29.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.6 5.7 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.6 4.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.6 1.7 GO:0051185 coenzyme transporter activity(GO:0051185)
0.6 11.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.6 2.2 GO:0004461 lactose synthase activity(GO:0004461)
0.5 16.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 4.9 GO:0070883 pre-miRNA binding(GO:0070883)
0.5 10.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.5 2.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.4 6.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 2.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.4 7.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 1.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.3 5.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 16.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.3 3.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 3.9 GO:1990239 steroid hormone binding(GO:1990239)
0.3 1.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 8.1 GO:0005123 death receptor binding(GO:0005123)
0.2 17.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 3.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 2.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290) O-acetyltransferase activity(GO:0016413)
0.2 5.7 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.2 4.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 2.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 9.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 2.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 5.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 9.3 GO:0051082 unfolded protein binding(GO:0051082)
0.1 3.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 3.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 3.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 5.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 13.1 GO:0005125 cytokine activity(GO:0005125)
0.1 1.2 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 6.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 0.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 7.8 GO:0008201 heparin binding(GO:0008201)
0.0 3.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 18.9 GO:0045296 cadherin binding(GO:0045296)
0.0 1.6 GO:0019894 kinesin binding(GO:0019894)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 25.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 3.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 6.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.8 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.7 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 4.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 16.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 7.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 5.0 PID ARF 3PATHWAY Arf1 pathway
0.2 12.8 PID LKB1 PATHWAY LKB1 signaling events
0.2 8.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 6.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 28.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 10.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 7.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 10.4 PID AP1 PATHWAY AP-1 transcription factor network
0.1 4.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.3 PID IL1 PATHWAY IL1-mediated signaling events
0.1 6.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 11.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 18.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.2 20.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.0 25.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 21.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 17.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.6 44.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.5 9.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.5 22.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.5 20.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.4 9.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 6.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4 16.2