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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CREB5_CREM_JUNB

Z-value: 0.55

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Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
ENSG00000146592.12 cAMP responsive element binding protein 5
ENSG00000095794.15 cAMP responsive element modulator
ENSG00000171223.4 JunB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

Activity profile of CREB5_CREM_JUNB motif

Sorted Z-values of CREB5_CREM_JUNB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_44258360 53.11 ENST00000330884.4
ENST00000249130.5
sulfotransferase family 4A, member 1
chrX_-_13956497 38.92 ENST00000398361.3
glycoprotein M6B
chrX_-_13956737 35.61 ENST00000454189.2
glycoprotein M6B
chr2_+_149632783 31.28 ENST00000435030.1
kinesin family member 5C
chr6_-_46293378 31.21 ENST00000330430.6
regulator of calcineurin 2
chr8_-_27115931 30.71 ENST00000523048.1
stathmin-like 4
chr20_+_10199468 30.59 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr2_-_224467093 28.67 ENST00000305409.2
secretogranin II
chrX_-_47479246 26.64 ENST00000295987.7
ENST00000340666.4
synapsin I
chr8_-_27115903 26.22 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr20_+_5892037 24.16 ENST00000378961.4
chromogranin B (secretogranin 1)
chr16_+_29911666 23.04 ENST00000563177.1
ENST00000483405.1
aspartate beta-hydroxylase domain containing 1
chr12_+_10365404 22.69 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr6_-_3157760 21.68 ENST00000333628.3
tubulin, beta 2A class IIa
chr16_+_29911864 20.43 ENST00000308748.5
aspartate beta-hydroxylase domain containing 1
chr17_+_42385927 20.15 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
RUN domain containing 3A
chr11_-_1593150 20.05 ENST00000397374.3
dual specificity phosphatase 8
chr22_+_32340481 19.70 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr15_+_75287861 19.57 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
secretory carrier membrane protein 5
chr16_+_56225248 19.48 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr11_+_117070037 19.42 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
transgelin
chr2_-_216300784 18.74 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr1_+_228353495 18.70 ENST00000366711.3
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr3_+_158991025 18.32 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr3_+_156544057 18.26 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
leucine, glutamate and lysine rich 1
chr18_-_5540471 18.23 ENST00000581833.1
ENST00000544123.1
ENST00000342933.3
ENST00000400111.3
ENST00000585142.1
erythrocyte membrane protein band 4.1-like 3
chrX_-_13835147 18.07 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr22_+_32340447 17.94 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr19_-_57352064 17.77 ENST00000326441.9
ENST00000593695.1
ENST00000599577.1
ENST00000594389.1
ENST00000423103.2
ENST00000598410.1
ENST00000593711.1
ENST00000391708.3
ENST00000221722.5
ENST00000599935.1
paternally expressed 3
zinc finger, imprinted 2
chr5_-_138210977 17.44 ENST00000274711.6
ENST00000521094.2
leucine rich repeat transmembrane neuronal 2
chr14_+_93389425 17.43 ENST00000216492.5
ENST00000334654.4
chromogranin A (parathyroid secretory protein 1)
chr11_-_111782696 16.83 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr6_+_39760129 16.60 ENST00000274867.4
dishevelled associated activator of morphogenesis 2
chr16_+_2039946 16.58 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr3_+_62304712 16.43 ENST00000494481.1
chromosome 3 open reading frame 14
chr3_+_159570722 15.86 ENST00000482804.1
schwannomin interacting protein 1
chr1_+_99729813 15.55 ENST00000457765.1
Lipid phosphate phosphatase-related protein type 4
chr14_+_101292445 15.53 ENST00000429159.2
ENST00000520714.1
ENST00000522771.2
ENST00000424076.3
ENST00000423456.1
ENST00000521404.1
ENST00000556736.1
ENST00000451743.2
ENST00000398518.2
ENST00000554639.1
ENST00000452120.2
ENST00000519709.1
ENST00000412736.2
maternally expressed 3 (non-protein coding)
chr3_-_187388173 15.21 ENST00000287641.3
somatostatin
chrX_-_13835461 14.98 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr3_+_62304648 14.82 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
chromosome 3 open reading frame 14
chr20_+_17207665 14.80 ENST00000536609.1
proprotein convertase subtilisin/kexin type 2
chr11_-_111782484 14.76 ENST00000533971.1
crystallin, alpha B
chr20_-_3154162 14.42 ENST00000360342.3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr20_+_17207636 14.42 ENST00000262545.2
proprotein convertase subtilisin/kexin type 2
chr15_+_68871308 14.23 ENST00000261861.5
coronin, actin binding protein, 2B
chr6_-_56819385 13.77 ENST00000370754.5
ENST00000449297.2
dystonin
chr6_-_70506963 13.61 ENST00000370577.3
LMBR1 domain containing 1
chr14_-_93651186 13.13 ENST00000556883.1
ENST00000298894.4
modulator of apoptosis 1
chr14_+_104095514 13.03 ENST00000348520.6
ENST00000380038.3
ENST00000389744.4
ENST00000557575.1
ENST00000553286.1
ENST00000347839.6
ENST00000555836.1
ENST00000334553.6
ENST00000246489.7
ENST00000557450.1
ENST00000452929.2
ENST00000554280.1
ENST00000445352.4
kinesin light chain 1
chr15_+_68871569 12.98 ENST00000566799.1
coronin, actin binding protein, 2B
chr16_+_2564254 12.95 ENST00000565223.1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr1_+_168148273 12.88 ENST00000367830.3
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr11_-_123525289 12.79 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chr9_+_17579084 12.62 ENST00000380607.4
SH3-domain GRB2-like 2
chr3_-_33759541 12.54 ENST00000468888.2
cytoplasmic linker associated protein 2
chr3_+_10068095 12.52 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr5_-_172198190 12.50 ENST00000239223.3
dual specificity phosphatase 1
chr9_+_137967366 12.41 ENST00000252854.4
olfactomedin 1
chr12_+_12938541 11.76 ENST00000356591.4
apolipoprotein L domain containing 1
chr4_+_113739244 11.41 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ankyrin 2, neuronal
chr12_+_7282795 11.04 ENST00000266546.6
calsyntenin 3
chrX_+_110339439 10.99 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
p21 protein (Cdc42/Rac)-activated kinase 3
chr1_+_110527308 10.98 ENST00000369799.5
adenosylhomocysteinase-like 1
chr10_-_99447024 10.93 ENST00000370626.3
arginine vasopressin-induced 1
chr16_+_2563871 10.92 ENST00000330398.4
ENST00000568562.1
ENST00000569317.1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Uncharacterized protein
chr17_-_71308119 10.62 ENST00000439510.2
ENST00000581014.1
ENST00000579611.1
CDC42 effector protein (Rho GTPase binding) 4
chr4_+_85504075 10.57 ENST00000295887.5
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr19_+_2841433 10.55 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
zinc finger protein 555
chr15_-_30113676 10.44 ENST00000400011.2
tight junction protein 1
chr3_-_33759699 10.44 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
cytoplasmic linker associated protein 2
chr19_+_18723660 10.42 ENST00000262817.3
transmembrane protein 59-like
chr3_+_184053703 10.32 ENST00000450976.1
ENST00000418281.1
ENST00000340957.5
ENST00000433578.1
family with sequence similarity 131, member A
chr16_+_22825475 10.27 ENST00000261374.3
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr9_-_99382065 10.04 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
cell division cycle 14B
chr2_+_220144052 9.90 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr7_-_31380502 9.81 ENST00000297142.3
neuronal differentiation 6
chr19_+_8455200 9.80 ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chr5_+_71403061 9.56 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr7_-_45128472 9.45 ENST00000490531.2
NAC alpha domain containing
chr8_-_102803163 9.44 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
neurocalcin delta
chr14_+_35515598 9.31 ENST00000280987.4
family with sequence similarity 177, member A1
chr17_+_53342311 9.30 ENST00000226067.5
hepatic leukemia factor
chr1_+_22379179 9.12 ENST00000315554.8
ENST00000421089.2
cell division cycle 42
chr9_-_99381660 9.05 ENST00000375240.3
ENST00000463569.1
cell division cycle 14B
chr4_-_87281196 8.96 ENST00000359221.3
mitogen-activated protein kinase 10
chr10_+_134351319 8.91 ENST00000368594.3
ENST00000368593.3
inositol polyphosphate-5-phosphatase, 40kDa
chr11_+_28129795 8.85 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr13_-_36429763 8.82 ENST00000379893.1
doublecortin-like kinase 1
chr1_+_9599540 8.49 ENST00000302692.6
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr1_+_36023370 8.47 ENST00000356090.4
ENST00000373243.2
neurochondrin
chr19_+_8455077 8.40 ENST00000328024.6
RAB11B, member RAS oncogene family
chr1_+_160175201 8.33 ENST00000368076.1
phosphoprotein enriched in astrocytes 15
chr1_+_28099683 8.24 ENST00000373943.4
syntaxin 12
chr21_-_44299626 8.17 ENST00000330317.2
ENST00000398208.2
WD repeat domain 4
chr11_+_62475130 8.12 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3
chr12_-_16761007 8.04 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr12_+_124997766 7.95 ENST00000543970.1
RP11-83B20.1
chr18_+_23806437 7.92 ENST00000578121.1
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr11_+_64692143 7.91 ENST00000164133.2
ENST00000532850.1
protein phosphatase 2, regulatory subunit B', beta
chr1_-_201476274 7.91 ENST00000340006.2
cysteine and glycine-rich protein 1
chr8_-_42065187 7.88 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
plasminogen activator, tissue
chr1_+_160175117 7.86 ENST00000360472.4
phosphoprotein enriched in astrocytes 15
chr13_-_29069232 7.74 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
fms-related tyrosine kinase 1
chr4_-_87281224 7.63 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr3_-_52001448 7.60 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
poly(rC) binding protein 4
chr2_+_220143989 7.54 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr9_-_131644202 7.53 ENST00000320665.6
ENST00000436267.2
cysteine conjugate-beta lyase, cytoplasmic
chr5_-_95297534 7.51 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr1_+_27719148 7.48 ENST00000374024.3
G protein-coupled receptor 3
chr19_-_56826157 7.38 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
zinc finger and SCAN domain containing 5A
chr7_-_37956409 7.27 ENST00000436072.2
secreted frizzled-related protein 4
chr18_+_76829441 7.22 ENST00000458297.2
ATPase, class II, type 9B
chr4_-_76598326 7.07 ENST00000503660.1
GTPase activating protein (SH3 domain) binding protein 2
chr1_-_1293904 7.06 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
matrix-remodelling associated 8
chr10_+_64133934 7.03 ENST00000395254.3
ENST00000395255.3
ENST00000410046.3
zinc finger protein 365
chr12_+_107168342 7.02 ENST00000392837.4
RIC8 guanine nucleotide exchange factor B
chr11_-_119187826 6.98 ENST00000264036.4
melanoma cell adhesion molecule
chr9_-_73029540 6.85 ENST00000377126.2
Kruppel-like factor 9
chr11_-_31839488 6.82 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
paired box 6
chr17_+_4046462 6.80 ENST00000577075.2
ENST00000575251.1
ENST00000301391.3
cytochrome b5 domain containing 2
chr19_-_5340730 6.79 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr16_-_90038866 6.74 ENST00000314994.3
CENPB DNA-binding domains containing 1
chr18_+_268148 6.72 ENST00000581677.1
RP11-705O1.8
chr2_-_241759622 6.65 ENST00000320389.7
ENST00000498729.2
kinesin family member 1A
chr16_+_27561449 6.64 ENST00000261588.4
KIAA0556
chr7_-_158622210 6.63 ENST00000251527.5
extended synaptotagmin-like protein 2
chr8_-_21966893 6.60 ENST00000522405.1
ENST00000522379.1
ENST00000309188.6
ENST00000521807.2
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr1_-_150602035 6.55 ENST00000503241.1
ENST00000369016.4
ENST00000339643.5
ENST00000271690.8
ENST00000356527.5
ENST00000362052.7
ENST00000503345.1
ENST00000369014.5
ENST00000369009.3
endosulfine alpha
chr5_-_57756087 6.55 ENST00000274289.3
polo-like kinase 2
chr4_-_186456766 6.54 ENST00000284771.6
PDZ and LIM domain 3
chr9_+_34179003 6.54 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
ubiquitin associated protein 1
chr22_+_38597889 6.48 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr6_+_31783291 6.46 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr3_+_130745688 6.38 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NIMA-related kinase 11
chr8_+_38243821 6.37 ENST00000519476.2
leucine zipper-EF-hand containing transmembrane protein 2
chr12_-_6772303 6.36 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
inhibitor of growth family, member 4
chr14_-_36278454 6.27 ENST00000307138.6
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr11_-_62474803 6.20 ENST00000533982.1
ENST00000360796.5
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr9_+_124088860 6.18 ENST00000373806.1
gelsolin
chr12_+_112856690 6.14 ENST00000392597.1
ENST00000351677.2
protein tyrosine phosphatase, non-receptor type 11
chr2_+_70142232 6.09 ENST00000540449.1
MAX dimerization protein 1
chr4_-_186456652 6.04 ENST00000284767.5
ENST00000284770.5
PDZ and LIM domain 3
chr17_+_66508537 5.96 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr12_+_107168418 5.95 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8 guanine nucleotide exchange factor B
chr8_-_42065075 5.95 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
plasminogen activator, tissue
chr8_-_141810634 5.94 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
protein tyrosine kinase 2
chr8_-_98290087 5.90 ENST00000322128.3
TSPY-like 5
chr6_+_44355257 5.77 ENST00000371477.3
cell division cycle 5-like
chr14_-_36278412 5.76 ENST00000389698.3
ENST00000258840.6
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr16_-_4897266 5.73 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
glyoxylate reductase 1 homolog (Arabidopsis)
chr17_+_66508154 5.66 ENST00000358598.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr3_-_133614421 5.64 ENST00000543906.1
RAB6B, member RAS oncogene family
chr3_+_130745769 5.61 ENST00000412440.2
NIMA-related kinase 11
chr6_+_148663729 5.60 ENST00000367467.3
SAM and SH3 domain containing 1
chr3_-_133614597 5.57 ENST00000285208.4
ENST00000460865.3
RAB6B, member RAS oncogene family
chr8_+_94929110 5.52 ENST00000520728.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_-_86850949 5.51 ENST00000237455.4
ring finger protein 103
chr8_-_18666360 5.50 ENST00000286485.8
pleckstrin and Sec7 domain containing 3
chr6_-_169654139 5.47 ENST00000366787.3
thrombospondin 2
chr8_+_94929077 5.41 ENST00000297598.4
ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_+_10183651 5.39 ENST00000305883.1
Kruppel-like factor 11
chr11_-_35547151 5.38 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
peptidase domain containing associated with muscle regeneration 1
chr8_-_18744528 5.36 ENST00000523619.1
pleckstrin and Sec7 domain containing 3
chr17_-_74236382 5.36 ENST00000592271.1
ENST00000319945.6
ENST00000269391.6
ring finger protein 157
chr12_+_122150646 5.35 ENST00000449592.2
transmembrane protein 120B
chr1_+_66797687 5.32 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
phosphodiesterase 4B, cAMP-specific
chr10_-_27444143 5.24 ENST00000477432.1
YME1-like 1 ATPase
chr2_-_220408430 5.24 ENST00000243776.6
chondroitin polymerizing factor
chr17_+_8339164 5.24 ENST00000582665.1
ENST00000334527.7
ENST00000299734.7
nudE neurodevelopment protein 1-like 1
chr2_+_11052054 5.23 ENST00000295082.1
potassium voltage-gated channel, subfamily F, member 1
chr1_-_212208842 5.22 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
integrator complex subunit 7
chr17_+_66509019 5.21 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr13_+_49822041 5.21 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
cytidine and dCMP deaminase domain containing 1
chr10_+_124134201 5.20 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_+_70142189 5.19 ENST00000264444.2
MAX dimerization protein 1
chr2_-_220174166 5.17 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
protein tyrosine phosphatase, receptor type, N
chr17_+_8339189 5.16 ENST00000585098.1
ENST00000380025.4
ENST00000402554.3
ENST00000584866.1
ENST00000582490.1
nudE neurodevelopment protein 1-like 1
chr8_+_94929168 5.15 ENST00000518107.1
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr9_-_131644306 5.13 ENST00000302586.3
cysteine conjugate-beta lyase, cytoplasmic
chr6_+_27833034 5.10 ENST00000357320.2
histone cluster 1, H2al
chr19_-_460996 5.06 ENST00000264554.6
SHC (Src homology 2 domain containing) transforming protein 2
chr2_-_98280383 5.03 ENST00000289228.5
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr10_+_123923105 4.98 ENST00000368999.1
transforming, acidic coiled-coil containing protein 2
chr3_+_50712672 4.98 ENST00000266037.9
dedicator of cytokinesis 3
chr15_-_42840961 4.96 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
leucine rich repeat containing 57
chr8_+_125954281 4.95 ENST00000510897.2
ENST00000533286.1
long intergenic non-protein coding RNA 964
chr1_+_70820451 4.94 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HERV-H LTR-associating 3
chr22_-_20104700 4.89 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr6_-_116575226 4.87 ENST00000420283.1
TSPY-like 4
chr17_+_41857793 4.80 ENST00000449302.3
chromosome 17 open reading frame 105
chr2_-_38604398 4.79 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
atlastin GTPase 2
chr22_+_41956767 4.75 ENST00000306149.7
cold shock domain containing C2, RNA binding
chr8_-_141774467 4.74 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr8_+_26240414 4.71 ENST00000380629.2
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr15_+_42841008 4.70 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS augmin-like complex, subunit 2
chr17_-_78450398 4.64 ENST00000306773.4
neuronal pentraxin I
chr8_-_18541603 4.60 ENST00000428502.2
pleckstrin and Sec7 domain containing 3
chr6_-_121655552 4.58 ENST00000275159.6
TBC1 domain family, member 32
chr1_-_203274418 4.57 ENST00000457348.1
long intergenic non-protein coding RNA 1136

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.8 107.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
7.3 21.9 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
5.8 29.2 GO:0030070 insulin processing(GO:0030070)
5.8 17.4 GO:2000705 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
5.0 20.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
4.9 14.7 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
4.8 23.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
4.4 17.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
3.8 11.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
3.4 27.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
3.3 26.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
3.1 6.1 GO:0043400 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
3.0 9.1 GO:1990502 dense core granule maturation(GO:1990502)
2.9 17.5 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
2.9 25.8 GO:0008090 retrograde axonal transport(GO:0008090)
2.7 23.9 GO:0007042 lysosomal lumen acidification(GO:0007042)
2.6 13.0 GO:0035617 stress granule disassembly(GO:0035617)
2.6 18.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
2.4 7.3 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
2.4 37.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
2.2 6.6 GO:0046066 dGDP metabolic process(GO:0046066)
2.1 12.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
2.1 16.6 GO:0007258 JUN phosphorylation(GO:0007258)
2.0 29.8 GO:0046325 negative regulation of glucose import(GO:0046325)
2.0 7.9 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
1.9 5.8 GO:1990637 response to prolactin(GO:1990637)
1.9 28.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
1.9 16.7 GO:0003190 atrioventricular valve formation(GO:0003190)
1.8 20.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
1.8 12.8 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.8 18.2 GO:0045054 constitutive secretory pathway(GO:0045054)
1.8 31.6 GO:0071850 mitotic cell cycle arrest(GO:0071850)
1.7 30.4 GO:0007021 tubulin complex assembly(GO:0007021)
1.7 5.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
1.7 10.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.6 6.5 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
1.6 6.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
1.6 4.8 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
1.6 11.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
1.6 11.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
1.5 53.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
1.5 10.6 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
1.5 4.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
1.5 17.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
1.4 4.3 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
1.4 5.7 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
1.4 12.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.4 5.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
1.4 6.8 GO:0003322 pancreatic A cell development(GO:0003322)
1.3 2.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.3 8.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.3 10.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
1.3 3.9 GO:0021779 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.3 52.9 GO:0007019 microtubule depolymerization(GO:0007019)
1.2 6.2 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
1.2 19.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.2 10.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
1.2 4.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
1.1 19.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.1 8.8 GO:0070475 rRNA base methylation(GO:0070475)
1.1 46.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
1.1 9.6 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.1 3.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.0 8.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.0 4.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.0 2.0 GO:0051795 positive regulation of catagen(GO:0051795)
1.0 9.9 GO:0042118 endothelial cell activation(GO:0042118)
1.0 6.9 GO:0051414 response to cortisol(GO:0051414)
1.0 2.9 GO:0007518 myoblast fate determination(GO:0007518)
0.9 7.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.9 2.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.9 30.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.9 2.8 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.9 12.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.9 7.4 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.9 2.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.9 16.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.9 8.9 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.9 18.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.8 2.5 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.8 4.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385)
0.8 4.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.8 3.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.8 2.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.8 11.8 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.8 2.3 GO:0061386 closure of optic fissure(GO:0061386)
0.8 2.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.8 15.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.8 17.7 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.8 2.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.7 4.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.7 2.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.7 1.4 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.7 2.8 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.7 7.0 GO:0061042 vascular wound healing(GO:0061042)
0.7 4.7 GO:2000370 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.7 1.3 GO:0010966 regulation of phosphate transport(GO:0010966)
0.5 2.7 GO:2000322 regulation of glucocorticoid receptor signaling pathway(GO:2000322) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.5 1.6 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.5 6.5 GO:0031167 rRNA methylation(GO:0031167)
0.5 2.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.5 10.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 13.8 GO:0031639 plasminogen activation(GO:0031639)
0.5 3.5 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.5 1.9 GO:0055064 chloride ion homeostasis(GO:0055064)
0.5 1.4 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.5 1.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.5 10.0 GO:0021542 dentate gyrus development(GO:0021542)
0.5 1.4 GO:0006014 D-ribose metabolic process(GO:0006014)
0.4 5.4 GO:0045475 locomotor rhythm(GO:0045475)
0.4 7.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.4 1.8 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.4 6.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.4 5.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.4 5.2 GO:0001553 luteinization(GO:0001553)
0.4 2.5 GO:0051012 microtubule sliding(GO:0051012)
0.4 8.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.4 10.4 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.4 4.1 GO:0006600 creatine metabolic process(GO:0006600)
0.4 7.7 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.4 4.1 GO:0000050 urea cycle(GO:0000050)
0.4 9.2 GO:0034389 lipid particle organization(GO:0034389)
0.4 13.1 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.4 19.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.4 11.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4 7.1 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.4 3.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 1.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 1.5 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.4 4.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.4 2.5 GO:0007341 penetration of zona pellucida(GO:0007341)
0.4 3.9 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 2.8 GO:0070166 enamel mineralization(GO:0070166)
0.3 2.8 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.3 6.5 GO:0007567 parturition(GO:0007567)
0.3 2.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.3 0.3 GO:0010825 positive regulation of centrosome duplication(GO:0010825) positive regulation of centriole replication(GO:0046601)
0.3 1.9 GO:0070836 caveola assembly(GO:0070836)
0.3 9.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.3 2.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.3 3.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 1.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 10.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 0.8 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3 2.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.3 0.8 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.3 2.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.3 8.5 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.3 2.7 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.3 1.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.3 2.7 GO:0007000 nucleolus organization(GO:0007000)
0.3 2.0 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.3 4.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 2.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 4.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 2.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 1.0 GO:1902218 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.2 1.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 0.7 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.2 0.7 GO:0006970 response to osmotic stress(GO:0006970)
0.2 1.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 2.7 GO:0015871 choline transport(GO:0015871)
0.2 5.3 GO:0045109 intermediate filament organization(GO:0045109)
0.2 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 1.7 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.2 1.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 3.7 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.2 13.8 GO:0021762 substantia nigra development(GO:0021762)
0.2 0.4 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 1.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 5.5 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 6.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 0.9 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 2.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.2 2.3 GO:0000338 protein deneddylation(GO:0000338)
0.2 0.8 GO:0015793 glycerol transport(GO:0015793)
0.2 14.6 GO:0007368 determination of left/right symmetry(GO:0007368)
0.2 2.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.2 1.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.2 1.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2 5.9 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 2.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 8.2 GO:0033344 cholesterol efflux(GO:0033344)
0.1 1.6 GO:0051412 response to corticosterone(GO:0051412)
0.1 3.2 GO:0003094 glomerular filtration(GO:0003094)
0.1 11.9 GO:0021987 cerebral cortex development(GO:0021987)
0.1 1.3 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966) positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416) negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 6.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.4 GO:0048073 regulation of eye pigmentation(GO:0048073) positive regulation of eye pigmentation(GO:0048075)
0.1 0.5 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 3.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 2.6 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 0.9 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.6 GO:0022615 protein to membrane docking(GO:0022615)
0.1 0.4 GO:1903208 positive regulation of mast cell cytokine production(GO:0032765) neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 2.3 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.2 GO:0070141 response to UV-A(GO:0070141)
0.1 0.3 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 3.2 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 4.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 3.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 3.4 GO:0050779 RNA destabilization(GO:0050779)
0.1 1.7 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 1.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 11.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.5 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.7 GO:0042730 fibrinolysis(GO:0042730)
0.1 7.0 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.9 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1 0.1 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 3.6 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.1 GO:0001842 neural fold formation(GO:0001842)
0.1 7.9 GO:0070527 platelet aggregation(GO:0070527)
0.1 6.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 1.7 GO:0006853 carnitine shuttle(GO:0006853) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 1.3 GO:1904778 protein localization to cell cortex(GO:0072697) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 3.3 GO:0016236 macroautophagy(GO:0016236)
0.1 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 7.0 GO:0030574 collagen catabolic process(GO:0030574)
0.1 2.1 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108) peptidyl-tyrosine modification(GO:0018212)
0.1 2.0 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 1.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 3.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 5.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 5.0 GO:0006936 muscle contraction(GO:0006936)
0.1 5.2 GO:0048477 oogenesis(GO:0048477)
0.1 5.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 3.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.9 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 1.2 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.1 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.1 9.0 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 6.0 GO:0098781 ncRNA transcription(GO:0098781)
0.1 2.1 GO:0001541 ovarian follicle development(GO:0001541)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.7 GO:0042254 ribosome biogenesis(GO:0042254)
0.1 0.8 GO:0003016 respiratory system process(GO:0003016)
0.1 2.7 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 0.3 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 4.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0032747 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.6 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 1.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 1.2 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.1 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 3.5 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 2.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 7.7 GO:0007517 muscle organ development(GO:0007517)
0.0 0.5 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 2.0 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.3 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.1 GO:0061035 regulation of chondrocyte differentiation(GO:0032330) regulation of cartilage development(GO:0061035)
0.0 9.8 GO:0043687 post-translational protein modification(GO:0043687)
0.0 1.5 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 1.3 GO:0043473 pigmentation(GO:0043473)
0.0 1.6 GO:0098916 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 0.6 GO:0006954 inflammatory response(GO:0006954)
0.0 0.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.7 GO:0030282 bone mineralization(GO:0030282)
0.0 0.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 30.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
3.5 10.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
3.4 13.8 GO:0031673 H zone(GO:0031673)
2.7 27.4 GO:0045180 basal cortex(GO:0045180)
2.7 23.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.4 31.3 GO:0035253 ciliary rootlet(GO:0035253)
2.2 35.7 GO:0097512 cardiac myofibril(GO:0097512)
1.7 21.9 GO:0005577 fibrinogen complex(GO:0005577)
1.5 28.7 GO:0031045 dense core granule(GO:0031045)
1.4 11.2 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
1.3 9.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.2 17.4 GO:0042583 chromaffin granule(GO:0042583)
1.1 3.3 GO:0043159 acrosomal matrix(GO:0043159)
1.1 18.2 GO:0033270 paranode region of axon(GO:0033270)
0.9 19.8 GO:0044295 axonal growth cone(GO:0044295)
0.9 6.5 GO:0000813 ESCRT I complex(GO:0000813)
0.9 18.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.9 12.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.8 26.6 GO:0000795 synaptonemal complex(GO:0000795)
0.8 22.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.8 2.3 GO:0044393 microspike(GO:0044393)
0.7 11.2 GO:0030478 actin cap(GO:0030478)
0.7 5.5 GO:0035976 AP1 complex(GO:0035976)
0.6 9.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.6 3.8 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.6 14.7 GO:0005921 gap junction(GO:0005921)
0.6 5.2 GO:0032039 integrator complex(GO:0032039)
0.6 4.0 GO:0032437 cuticular plate(GO:0032437)
0.6 41.9 GO:0014704 intercalated disc(GO:0014704)
0.6 2.8 GO:0070847 core mediator complex(GO:0070847)
0.5 7.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 27.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 7.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.5 3.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.5 8.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.5 7.0 GO:0005869 dynactin complex(GO:0005869)
0.4 8.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 2.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.4 3.9 GO:0016013 syntrophin complex(GO:0016013)
0.4 2.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.4 30.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 5.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 2.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.4 64.6 GO:0030426 growth cone(GO:0030426)
0.4 2.3 GO:0031082 BLOC complex(GO:0031082)
0.4 4.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 28.8 GO:0008021 synaptic vesicle(GO:0008021)
0.3 2.9 GO:0034464 BBSome(GO:0034464)
0.3 1.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 79.9 GO:0060076 excitatory synapse(GO:0060076)
0.3 1.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 1.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.3 19.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.3 2.3 GO:0070652 HAUS complex(GO:0070652)
0.2 3.7 GO:0035371 microtubule plus-end(GO:0035371)
0.2 1.5 GO:0043196 varicosity(GO:0043196)
0.2 1.9 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 0.7 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 1.2 GO:0032021 NELF complex(GO:0032021)
0.2 1.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 72.4 GO:0045121 membrane raft(GO:0045121)
0.2 2.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 19.8 GO:0043204 perikaryon(GO:0043204)
0.2 1.2 GO:0000242 pericentriolar material(GO:0000242)
0.2 1.0 GO:0032389 MutLalpha complex(GO:0032389)
0.2 5.5 GO:0032589 neuron projection membrane(GO:0032589)
0.2 2.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 16.9 GO:0005776 autophagosome(GO:0005776)
0.2 0.9 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 2.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 1.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 8.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 5.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 5.0 GO:0016592 mediator complex(GO:0016592)
0.2 17.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 2.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 8.0 GO:0000786 nucleosome(GO:0000786)
0.1 2.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 19.8 GO:0000922 spindle pole(GO:0000922)
0.1 5.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 10.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 12.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 5.5 GO:0005604 basement membrane(GO:0005604)
0.1 13.2 GO:0030018 Z disc(GO:0030018)
0.1 13.5 GO:0005814 centriole(GO:0005814)
0.1 2.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 4.7 GO:0016460 myosin II complex(GO:0016460)
0.1 1.6 GO:0005923 bicellular tight junction(GO:0005923) apical junction complex(GO:0043296) occluding junction(GO:0070160)
0.1 3.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.3 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.9 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.1 GO:0042627 chylomicron(GO:0042627)
0.1 3.0 GO:0005605 basal lamina(GO:0005605)
0.1 29.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 5.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 2.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 4.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 4.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.3 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 21.1 GO:0045177 apical part of cell(GO:0045177)
0.1 3.8 GO:0015030 Cajal body(GO:0015030)
0.1 1.1 GO:0043209 myelin sheath(GO:0043209)
0.1 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.1 12.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.9 GO:0043195 terminal bouton(GO:0043195)
0.0 8.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 5.8 GO:0030424 axon(GO:0030424)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 3.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 5.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 5.4 GO:0001650 fibrillar center(GO:0001650)
0.0 3.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 6.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 7.4 GO:0043235 receptor complex(GO:0043235)
0.0 1.1 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 1.7 GO:0031252 cell leading edge(GO:0031252)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.9 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 4.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 4.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 11.4 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0030133 transport vesicle(GO:0030133)

Gene overrepresentation in molecular_function category:

<
Log-likelihood per target  Total log-likelihood Term Description
5.4 32.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
4.5 13.6 GO:0015235 cobalamin transporter activity(GO:0015235)
3.9 11.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
3.5 10.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
2.9 8.8 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
2.9 20.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
2.8 16.6 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.7 16.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.6 12.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
2.3 53.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.9 5.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.9 20.9 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.8 11.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.8 10.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.7 20.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.6 22.7 GO:0030957 Tat protein binding(GO:0030957)
1.6 4.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
1.4 5.8 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.3 13.2 GO:0042731 PH domain binding(GO:0042731)
1.3 31.3 GO:0002162 dystroglycan binding(GO:0002162)
1.3 6.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.2 17.4 GO:0042043 neurexin family protein binding(GO:0042043)
1.2 29.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.2 3.5 GO:0000995 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) transcription factor activity, core RNA polymerase III binding(GO:0000995) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
1.2 30.1 GO:0031489 myosin V binding(GO:0031489)
1.1 4.5 GO:0008384 IkappaB kinase activity(GO:0008384)
1.1 21.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.1 7.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.0 3.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.0 32.2 GO:0017075 syntaxin-1 binding(GO:0017075)
1.0 31.6 GO:0005212 structural constituent of eye lens(GO:0005212)
1.0 6.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.9 2.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.9 23.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.8 2.5 GO:0004040 amidase activity(GO:0004040) fucose binding(GO:0042806)
0.8 9.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.7 13.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.7 7.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.7 4.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.7 2.1 GO:0017129 triglyceride binding(GO:0017129)
0.7 15.2 GO:0003777 microtubule motor activity(GO:0003777)
0.7 9.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.7 21.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.7 2.0 GO:0032427 GBD domain binding(GO:0032427)
0.7 2.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.7 5.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.6 6.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.6 6.2 GO:0045159 myosin II binding(GO:0045159)
0.6 19.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.6 6.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.6 27.9 GO:0042056 chemoattractant activity(GO:0042056)
0.6 15.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.6 4.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)