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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CUGGCUG

Z-value: 0.75

Motif logo

logo of

miRNA associated with seed CUGGCUG

NamemiRBASE accession
hsa-miR-3064-5p
MIMAT0019864
hsa-miR-6504-5p
MIMAT0025464

Activity profile of CUGGCUG motif

Sorted Z-values of CUGGCUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_40390930 4.05 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr13_+_27131887 3.55 ENST00000335327.5
WASF3
WAS protein family, member 3
chr11_-_12030629 3.53 ENST00000396505.2
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr2_+_149632783 3.28 ENST00000435030.1
KIF5C
kinesin family member 5C
chr11_+_45868957 3.22 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr8_-_9008206 3.13 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr6_+_36853607 2.92 ENST00000480824.2
ENST00000355190.3
ENST00000373685.1
C6orf89
chromosome 6 open reading frame 89
chr14_-_77787198 2.77 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr8_+_26435359 2.60 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr1_-_57045228 2.36 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr12_-_50297638 2.13 ENST00000320634.3
FAIM2
Fas apoptotic inhibitory molecule 2
chr11_+_123396528 2.13 ENST00000322282.7
ENST00000529750.1
GRAMD1B
GRAM domain containing 1B
chr17_-_36956155 2.05 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr11_-_73309228 2.04 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr1_+_160175117 2.03 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr1_-_35325400 2.01 ENST00000521580.2
SMIM12
small integral membrane protein 12
chr17_+_29718642 1.94 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr1_+_46972668 1.90 ENST00000371956.4
ENST00000360032.3
DMBX1
diencephalon/mesencephalon homeobox 1
chr3_-_128879875 1.86 ENST00000418265.1
ENST00000393292.3
ENST00000273541.8
ISY1-RAB43
ISY1
ISY1-RAB43 readthrough
ISY1 splicing factor homolog (S. cerevisiae)
chr7_+_102715315 1.84 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10
armadillo repeat containing 10
chr2_-_217560248 1.83 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr20_+_34700333 1.78 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr17_-_27893990 1.77 ENST00000307201.4
ABHD15
abhydrolase domain containing 15
chr20_+_36149602 1.69 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr16_+_29674540 1.68 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr2_-_69870835 1.68 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr5_-_132948216 1.68 ENST00000265342.7
FSTL4
follistatin-like 4
chr1_-_26372602 1.64 ENST00000374278.3
ENST00000374276.3
SLC30A2
solute carrier family 30 (zinc transporter), member 2
chr2_+_25015968 1.55 ENST00000380834.2
ENST00000473706.1
CENPO
centromere protein O
chr12_+_123319973 1.54 ENST00000253083.4
HIP1R
huntingtin interacting protein 1 related
chr7_+_65338230 1.47 ENST00000360768.3
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr17_-_17875688 1.44 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr14_+_65171099 1.43 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr15_-_64648273 1.42 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
CSNK1G1
casein kinase 1, gamma 1
chr14_-_95786200 1.42 ENST00000298912.4
CLMN
calmin (calponin-like, transmembrane)
chr15_-_65579177 1.41 ENST00000444347.2
ENST00000261888.6
PARP16
poly (ADP-ribose) polymerase family, member 16
chr11_-_115375107 1.40 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr8_-_98290087 1.36 ENST00000322128.3
TSPYL5
TSPY-like 5
chr17_-_4607335 1.35 ENST00000570571.1
ENST00000575101.1
ENST00000436683.2
ENST00000574876.1
PELP1
proline, glutamate and leucine rich protein 1
chr20_-_1472029 1.35 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr11_-_59383617 1.31 ENST00000263847.1
OSBP
oxysterol binding protein
chr6_+_41040678 1.30 ENST00000341376.6
ENST00000353205.5
NFYA
nuclear transcription factor Y, alpha
chr9_+_34958254 1.28 ENST00000242315.3
KIAA1045
KIAA1045
chr20_-_41818373 1.27 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr8_+_42752053 1.26 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr1_-_109940550 1.25 ENST00000256637.6
SORT1
sortilin 1
chr6_-_44281043 1.23 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr7_+_77325738 1.22 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr17_-_7197881 1.22 ENST00000007699.5
YBX2
Y box binding protein 2
chr1_+_205012293 1.20 ENST00000331830.4
CNTN2
contactin 2 (axonal)
chr11_-_72385437 1.20 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr12_-_58135903 1.20 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_+_37787262 1.19 ENST00000287218.4
ZFAND3
zinc finger, AN1-type domain 3
chr16_+_31085714 1.18 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr16_-_86588627 1.17 ENST00000565482.1
ENST00000564364.1
ENST00000561989.1
ENST00000543303.2
ENST00000381214.5
ENST00000360900.6
ENST00000322911.6
ENST00000546093.1
ENST00000569000.1
ENST00000562994.1
ENST00000561522.1
MTHFSD
methenyltetrahydrofolate synthetase domain containing
chr18_+_9708162 1.16 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chr12_-_54673871 1.16 ENST00000209875.4
CBX5
chromobox homolog 5
chr5_+_177540444 1.14 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr10_+_104678032 1.11 ENST00000369878.4
ENST00000369875.3
CNNM2
cyclin M2
chr1_-_112281875 1.09 ENST00000527621.1
ENST00000534365.1
ENST00000357260.5
FAM212B
family with sequence similarity 212, member B
chr10_-_120514720 1.08 ENST00000369151.3
ENST00000340214.4
CACUL1
CDK2-associated, cullin domain 1
chr9_-_91793675 1.08 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr15_+_92937058 1.07 ENST00000268164.3
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr11_-_134281812 1.07 ENST00000392580.1
ENST00000312527.4
B3GAT1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr3_+_50606577 1.06 ENST00000434410.1
ENST00000232854.4
HEMK1
HemK methyltransferase family member 1
chr3_-_133614597 1.04 ENST00000285208.4
ENST00000460865.3
RAB6B
RAB6B, member RAS oncogene family
chr22_-_39239987 1.03 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chr22_-_19435755 1.03 ENST00000542103.1
ENST00000399562.4
C22orf39
chromosome 22 open reading frame 39
chr19_-_11591848 1.01 ENST00000359227.3
ELAVL3
ELAV like neuron-specific RNA binding protein 3
chr17_+_36508111 1.01 ENST00000331159.5
ENST00000577233.1
SOCS7
suppressor of cytokine signaling 7
chr3_+_139654018 0.99 ENST00000458420.3
CLSTN2
calsyntenin 2
chr5_-_160973649 0.99 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr17_+_47653178 0.98 ENST00000328741.5
NXPH3
neurexophilin 3
chr20_-_48099182 0.95 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr6_-_35109080 0.95 ENST00000486638.1
ENST00000505400.1
ENST00000412155.2
ENST00000373979.2
ENST00000507706.1
ENST00000444780.2
ENST00000492680.2
TCP11
t-complex 11, testis-specific
chr19_+_34287751 0.94 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr10_-_75634260 0.92 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr19_-_14316980 0.92 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr15_-_86338134 0.89 ENST00000337975.5
KLHL25
kelch-like family member 25
chr1_+_38022513 0.89 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr18_+_54318616 0.87 ENST00000254442.3
WDR7
WD repeat domain 7
chr17_-_48207157 0.87 ENST00000330175.4
ENST00000503131.1
SAMD14
sterile alpha motif domain containing 14
chr12_-_49110613 0.86 ENST00000261900.3
CCNT1
cyclin T1
chr14_-_75389975 0.86 ENST00000555647.1
ENST00000557413.1
RPS6KL1
ribosomal protein S6 kinase-like 1
chr2_+_105471969 0.85 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr10_-_105615164 0.83 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr3_-_12200851 0.82 ENST00000287814.4
TIMP4
TIMP metallopeptidase inhibitor 4
chr1_-_33430286 0.78 ENST00000373456.7
ENST00000356990.5
ENST00000235150.4
RNF19B
ring finger protein 19B
chr2_-_166930131 0.77 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr17_-_33775760 0.77 ENST00000534689.1
ENST00000532210.1
ENST00000526861.1
ENST00000531588.1
ENST00000285013.6
SLFN13
schlafen family member 13
chrX_+_119495934 0.76 ENST00000218008.3
ENST00000361319.3
ENST00000539306.1
ATP1B4
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr19_-_14228541 0.76 ENST00000590853.1
ENST00000308677.4
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr16_-_65155833 0.76 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_+_11333245 0.76 ENST00000376810.5
UBIAD1
UbiA prenyltransferase domain containing 1
chr4_+_72204755 0.75 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr16_-_17564738 0.74 ENST00000261381.6
XYLT1
xylosyltransferase I
chr3_-_48700310 0.72 ENST00000164024.4
ENST00000544264.1
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3
chr20_-_35374456 0.72 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
NDRG3
NDRG family member 3
chr7_-_98741642 0.72 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr7_+_31092076 0.68 ENST00000304166.4
ADCYAP1R1
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
chr11_+_118477144 0.68 ENST00000361417.2
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr17_-_617949 0.68 ENST00000401468.3
ENST00000574029.1
ENST00000291074.5
ENST00000571805.1
ENST00000437048.2
ENST00000446250.2
VPS53
vacuolar protein sorting 53 homolog (S. cerevisiae)
chr1_+_50574585 0.65 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr17_-_1420182 0.65 ENST00000421807.2
INPP5K
inositol polyphosphate-5-phosphatase K
chr1_+_27561007 0.63 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr22_-_43010928 0.63 ENST00000348657.2
ENST00000252115.5
POLDIP3
polymerase (DNA-directed), delta interacting protein 3
chr1_+_151171012 0.61 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr8_+_145743360 0.60 ENST00000527730.1
ENST00000529022.1
ENST00000292524.1
LRRC14
leucine rich repeat containing 14
chr2_-_239197201 0.60 ENST00000254658.3
PER2
period circadian clock 2
chr3_-_186080012 0.58 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr7_+_108210012 0.58 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr15_+_64443905 0.57 ENST00000325881.4
SNX22
sorting nexin 22
chr1_-_1677358 0.56 ENST00000355439.2
ENST00000400924.1
ENST00000246421.4
SLC35E2
solute carrier family 35, member E2
chr1_+_159141397 0.56 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr19_+_3359561 0.52 ENST00000589123.1
ENST00000346156.5
ENST00000395111.3
ENST00000586919.1
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr19_+_57019212 0.52 ENST00000308031.5
ENST00000591537.1
ZNF471
zinc finger protein 471
chr22_+_20067738 0.52 ENST00000351989.3
ENST00000383024.2
DGCR8
DGCR8 microprocessor complex subunit
chr5_-_133512683 0.52 ENST00000353411.6
SKP1
S-phase kinase-associated protein 1
chr2_+_204192942 0.52 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr22_+_42229100 0.51 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chr11_-_62521614 0.51 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr2_+_135676381 0.49 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
CCNT2
cyclin T2
chr20_-_48184638 0.48 ENST00000244043.4
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr16_+_68298405 0.48 ENST00000219343.6
ENST00000566834.1
ENST00000566454.1
SLC7A6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr12_-_57400227 0.48 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr11_+_82868030 0.48 ENST00000298281.4
ENST00000530660.1
PCF11
PCF11 cleavage and polyadenylation factor subunit
chr20_+_35974532 0.47 ENST00000373578.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr17_-_27916621 0.47 ENST00000225394.3
GIT1
G protein-coupled receptor kinase interacting ArfGAP 1
chr11_+_120382417 0.47 ENST00000527524.2
ENST00000375081.2
GRIK4
AP002348.1
glutamate receptor, ionotropic, kainate 4
Uncharacterized protein
chr8_-_93115445 0.46 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_3539558 0.46 ENST00000225519.3
SHPK
sedoheptulokinase
chr8_+_143530791 0.45 ENST00000517894.1
BAI1
brain-specific angiogenesis inhibitor 1
chr12_+_52306113 0.44 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1
activin A receptor type II-like 1
chr3_+_44379944 0.44 ENST00000396078.3
ENST00000342649.4
TCAIM
T cell activation inhibitor, mitochondrial
chr10_-_70287231 0.44 ENST00000609923.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr12_-_56727487 0.43 ENST00000548043.1
ENST00000425394.2
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr5_+_175223313 0.42 ENST00000359546.4
CPLX2
complexin 2
chr9_-_132404374 0.42 ENST00000277459.4
ENST00000450050.2
ENST00000277458.4
ASB6
ankyrin repeat and SOCS box containing 6
chr1_+_28696111 0.42 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr9_-_37034028 0.42 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr5_+_149887672 0.42 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr8_-_21646311 0.41 ENST00000524240.1
ENST00000400782.4
GFRA2
GDNF family receptor alpha 2
chr2_+_27193480 0.40 ENST00000233121.2
ENST00000405074.3
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr2_+_134877740 0.39 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr17_-_38721711 0.38 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr5_+_148521046 0.38 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
ABLIM3
actin binding LIM protein family, member 3
chr2_-_97405775 0.37 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr20_+_3451650 0.37 ENST00000262919.5
ATRN
attractin
chr9_-_35619539 0.37 ENST00000396757.1
CD72
CD72 molecule
chr19_-_15560730 0.37 ENST00000389282.4
ENST00000263381.7
WIZ
widely interspaced zinc finger motifs
chr6_-_31864977 0.36 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr3_-_58196688 0.35 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr1_+_110453203 0.34 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr17_-_27169745 0.34 ENST00000583307.1
ENST00000581229.1
ENST00000582266.1
ENST00000577376.1
ENST00000577682.1
ENST00000581381.1
ENST00000341217.5
ENST00000581407.1
ENST00000583522.1
FAM222B
family with sequence similarity 222, member B
chr5_-_121413974 0.33 ENST00000231004.4
LOX
lysyl oxidase
chr20_+_33814457 0.33 ENST00000246186.6
MMP24
matrix metallopeptidase 24 (membrane-inserted)
chr19_+_34745442 0.33 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355
KIAA0355
chr10_+_102295616 0.33 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr5_-_141257954 0.33 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr17_-_26941179 0.31 ENST00000301037.5
ENST00000530121.1
ENST00000525510.1
ENST00000577790.1
ENST00000531839.1
ENST00000534850.1
SGK494
RP11-192H23.4
uncharacterized serine/threonine-protein kinase SgK494
Uncharacterized protein
chr7_-_99036270 0.31 ENST00000430029.1
ENST00000419981.1
ENST00000292478.4
PTCD1
pentatricopeptide repeat domain 1
chr3_+_196594727 0.30 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
SENP5
SUMO1/sentrin specific peptidase 5
chr19_+_16296191 0.29 ENST00000589852.1
ENST00000263384.7
ENST00000588367.1
ENST00000587351.1
FAM32A
family with sequence similarity 32, member A
chrY_+_15016725 0.29 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr17_+_35294075 0.27 ENST00000254457.5
LHX1
LIM homeobox 1
chr11_+_71640071 0.26 ENST00000533380.1
ENST00000393713.3
ENST00000545854.1
RNF121
ring finger protein 121
chr5_-_146833485 0.26 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr17_+_61627814 0.26 ENST00000310827.4
ENST00000431926.1
ENST00000415273.2
DCAF7
DDB1 and CUL4 associated factor 7
chr16_-_71843047 0.26 ENST00000299980.4
ENST00000393512.3
AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr1_-_55266926 0.26 ENST00000371276.4
TTC22
tetratricopeptide repeat domain 22
chr1_+_16693578 0.25 ENST00000401088.4
ENST00000471507.1
ENST00000401089.3
ENST00000375590.3
ENST00000492354.1
SZRD1
SUZ RNA binding domain containing 1
chr12_-_105630016 0.25 ENST00000258530.3
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr14_+_23775971 0.25 ENST00000250405.5
BCL2L2
BCL2-like 2
chr7_+_35840542 0.24 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr3_+_9834227 0.24 ENST00000287613.7
ENST00000397261.3
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr11_+_66610883 0.24 ENST00000309657.3
ENST00000524506.1
RCE1
Ras converting CAAX endopeptidase 1
chr22_+_39795746 0.22 ENST00000216160.6
ENST00000331454.3
TAB1
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr12_-_53074182 0.21 ENST00000252244.3
KRT1
keratin 1
chr10_+_103911926 0.21 ENST00000605788.1
ENST00000405356.1
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr6_-_166075557 0.19 ENST00000539869.2
ENST00000366882.1
PDE10A
phosphodiesterase 10A
chr12_+_54943134 0.19 ENST00000243052.3
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr20_+_30795664 0.18 ENST00000375749.3
ENST00000375730.3
ENST00000539210.1
POFUT1
protein O-fucosyltransferase 1
chr1_+_206808918 0.18 ENST00000367108.3
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr15_+_92396920 0.16 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr11_-_106889250 0.16 ENST00000526355.2
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr11_+_72929319 0.15 ENST00000393597.2
ENST00000311131.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr19_+_11466062 0.14 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr15_+_81489213 0.13 ENST00000559383.1
ENST00000394660.2
IL16
interleukin 16
chr1_+_154300217 0.11 ENST00000368489.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chrX_+_46306624 0.11 ENST00000360017.5
KRBOX4
KRAB box domain containing 4
chr12_-_49449107 0.11 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D
chr5_+_153825510 0.11 ENST00000297109.6
SAP30L
SAP30-like
chr9_+_77112244 0.11 ENST00000376896.3
RORB
RAR-related orphan receptor B
chr3_+_48956249 0.11 ENST00000452882.1
ENST00000430423.1
ENST00000356401.4
ENST00000449376.1
ENST00000420814.1
ENST00000449729.1
ENST00000433170.1
ARIH2
ariadne RBR E3 ubiquitin protein ligase 2
chr5_-_147162078 0.10 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr12_-_58027138 0.09 ENST00000341156.4
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr14_+_55034599 0.08 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chrX_+_12156582 0.08 ENST00000380682.1
FRMPD4
FERM and PDZ domain containing 4
chr1_+_153700518 0.07 ENST00000318967.2
ENST00000456435.1
ENST00000435409.2
INTS3
integrator complex subunit 3
chr15_-_61521495 0.07 ENST00000335670.6
RORA
RAR-related orphan receptor A

Network of associatons between targets according to the STRING database.

First level regulatory network of CUGGCUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.9 3.5 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.6 1.8 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.6 1.7 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.6 2.8 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.5 1.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.5 1.9 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.4 1.7 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.4 1.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.4 1.2 GO:0031133 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.4 1.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.4 2.9 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.4 1.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 1.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.3 0.9 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.3 1.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.3 1.2 GO:0009386 translational attenuation(GO:0009386)
0.3 2.0 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.3 0.3 GO:0060067 cervix development(GO:0060067)
0.2 0.7 GO:1902534 single-organism membrane invagination(GO:1902534)
0.2 1.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.2 3.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 2.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 0.8 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 1.9 GO:0008343 adult feeding behavior(GO:0008343)
0.2 0.7 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.2 1.9 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 2.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 0.9 GO:0072240 thick ascending limb development(GO:0072023) DCT cell differentiation(GO:0072069) metanephric thick ascending limb development(GO:0072233) metanephric DCT cell differentiation(GO:0072240)
0.2 1.7 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.6 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.2 2.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 0.5 GO:0035963 cellular response to interleukin-13(GO:0035963)
0.1 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 2.0 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.4 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.4 GO:2000525 dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 1.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 3.5 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.6 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 1.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 3.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.8 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.8 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 1.1 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 1.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.7 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.3 GO:1903971 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.3 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 1.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 1.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.5 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.3 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 1.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.0 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.9 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 2.0 GO:0006284 base-excision repair(GO:0006284)
0.0 1.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.4 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.7 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.4 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.4 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.3 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.0 1.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 1.9 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.6 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 1.3 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0006468 protein phosphorylation(GO:0006468)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 1.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0071020 post-spliceosomal complex(GO:0071020)
0.3 1.3 GO:0070695 FHF complex(GO:0070695)
0.3 3.1 GO:0042587 glycogen granule(GO:0042587)
0.3 3.3 GO:0035253 ciliary rootlet(GO:0035253)
0.2 1.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 0.7 GO:1990745 EARP complex(GO:1990745)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 1.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.8 GO:0044194 cytolytic granule(GO:0044194)
0.1 1.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 2.0 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.7 GO:0045180 basal cortex(GO:0045180)
0.1 0.4 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.5 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 1.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.7 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.9 GO:0030286 dynein complex(GO:0030286)
0.0 1.3 GO:0055037 recycling endosome(GO:0055037)
0.0 1.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.2 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 1.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.6 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.7 2.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.6 1.7 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.5 2.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.4 1.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.4 1.5 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.4 1.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 1.3 GO:0070097 delta-catenin binding(GO:0070097)
0.3 1.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 0.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 1.7 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 1.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 3.2 GO:0009881 photoreceptor activity(GO:0009881)
0.2 0.6 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 1.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 1.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 2.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 1.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.0 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.4 GO:0070984 SET domain binding(GO:0070984)
0.1 1.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 3.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.8 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.7 GO:0048185 activin binding(GO:0048185)
0.0 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.8 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 3.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.1 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 1.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.2 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 1.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.3 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.9 GO:0015297 antiporter activity(GO:0015297)
0.0 0.5 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation