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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CUX2

Z-value: 1.75

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Transcription factors associated with CUX2

Gene Symbol Gene ID Gene Info
CUX2
ENSG00000111249.9 cut like homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX2hg19_v2_chr12_+_111471828_1114719750.491.2e-14Click!

Activity profile of CUX2 motif

Sorted Z-values of CUX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_186125077 61.07 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
KIAA1430
chr19_+_45409011 42.07 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr11_+_82612740 41.35 ENST00000524921.1
ENST00000528759.1
ENST00000525361.1
ENST00000430323.2
ENST00000533655.1
ENST00000532764.1
ENST00000532589.1
ENST00000525388.1
C11orf82
chromosome 11 open reading frame 82
chr12_-_91573132 38.41 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr8_+_94241867 38.11 ENST00000598428.1
AC016885.1
Uncharacterized protein
chr16_+_58283814 37.18 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr11_+_57365150 36.18 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr2_-_86333244 36.09 ENST00000263857.6
ENST00000409681.1
POLR1A
polymerase (RNA) I polypeptide A, 194kDa
chr8_-_120651020 35.10 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_-_90751038 29.52 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr15_+_99791567 29.04 ENST00000558879.1
ENST00000301981.3
ENST00000422500.2
ENST00000447360.2
ENST00000442993.2
LRRC28
leucine rich repeat containing 28
chr15_+_69307028 28.06 ENST00000388866.3
ENST00000530406.2
NOX5
NADPH oxidase, EF-hand calcium binding domain 5
chr12_-_91573249 27.79 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr3_-_58563094 26.39 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr1_-_109618566 25.59 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr2_+_54198210 25.47 ENST00000607452.1
ENST00000422521.2
ACYP2
acylphosphatase 2, muscle type
chr17_+_56315936 24.86 ENST00000543544.1
LPO
lactoperoxidase
chr12_-_91546926 24.85 ENST00000550758.1
DCN
decorin
chr6_+_71122974 23.88 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr4_+_74275057 23.41 ENST00000511370.1
ALB
albumin
chr21_-_37270727 22.62 ENST00000599809.1
FKSG68
FKSG68
chr1_-_100231349 22.31 ENST00000287474.5
ENST00000414213.1
FRRS1
ferric-chelate reductase 1
chr4_+_71587669 21.91 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr19_-_4535233 21.84 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr12_-_11422630 21.76 ENST00000381842.3
ENST00000538488.1
PRB3
proline-rich protein BstNI subfamily 3
chr1_+_196912902 21.72 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr4_+_71263599 21.69 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chr7_+_16828866 21.54 ENST00000597084.1
AC073333.1
Uncharacterized protein
chr1_+_104159999 21.05 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr1_+_33439268 20.32 ENST00000594612.1
FKSG48
FKSG48
chr17_+_56315787 20.19 ENST00000262290.4
ENST00000421678.2
LPO
lactoperoxidase
chr6_+_42847649 19.82 ENST00000424341.2
ENST00000602561.1
RPL7L1
ribosomal protein L7-like 1
chr12_-_45269430 19.75 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr8_-_82395461 19.50 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr19_-_36297632 19.50 ENST00000588266.2
PRODH2
proline dehydrogenase (oxidase) 2
chr11_+_43380459 19.30 ENST00000299240.6
ENST00000039989.4
TTC17
tetratricopeptide repeat domain 17
chr17_-_4167142 19.27 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr5_+_175490540 19.10 ENST00000515817.1
FAM153B
family with sequence similarity 153, member B
chr2_+_95691417 18.78 ENST00000309988.4
MAL
mal, T-cell differentiation protein
chr2_+_95691445 18.71 ENST00000353004.3
ENST00000354078.3
ENST00000349807.3
MAL
mal, T-cell differentiation protein
chr12_-_45270151 18.66 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr6_+_56954867 18.61 ENST00000370708.4
ENST00000370702.1
ZNF451
zinc finger protein 451
chr5_-_43412418 18.38 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr12_-_45270077 18.35 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr14_+_74417192 18.23 ENST00000554320.1
COQ6
coenzyme Q6 monooxygenase
chr11_+_92085262 17.92 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr11_+_49050504 17.85 ENST00000332682.7
TRIM49B
tripartite motif containing 49B
chr11_+_60260248 17.77 ENST00000526784.1
ENST00000016913.4
ENST00000537076.1
ENST00000530007.1
MS4A12
membrane-spanning 4-domains, subfamily A, member 12
chr5_-_115910630 17.15 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr18_+_29171689 17.12 ENST00000237014.3
TTR
transthyretin
chr5_+_59726565 16.68 ENST00000412930.2
FKSG52
FKSG52
chrX_-_13835147 16.66 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr2_+_207220463 16.57 ENST00000598562.1
AC017081.1
Uncharacterized protein
chr2_-_26700900 16.50 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
OTOF
otoferlin
chr5_+_173472607 16.30 ENST00000303177.3
ENST00000519867.1
NSG2
Neuron-specific protein family member 2
chr5_-_146302078 16.20 ENST00000508545.2
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr5_-_11588907 16.08 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr3_-_194072019 16.04 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chrM_+_4431 15.94 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr8_-_8318847 15.93 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr6_+_73076432 15.78 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_152830479 15.76 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr1_+_12976450 15.66 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr1_+_152850787 15.36 ENST00000368765.3
SMCP
sperm mitochondria-associated cysteine-rich protein
chr2_-_152830441 15.24 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr6_-_152958521 15.01 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_-_135290705 14.96 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chrX_+_70586082 14.93 ENST00000373790.4
ENST00000449580.1
ENST00000423759.1
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr8_+_120885949 14.86 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chr1_+_13910194 14.78 ENST00000376057.4
ENST00000510906.1
PDPN
podoplanin
chr12_-_11422739 14.62 ENST00000279573.7
PRB3
proline-rich protein BstNI subfamily 3
chr15_-_47426320 14.59 ENST00000557832.1
FKSG62
FKSG62
chr12_-_71182695 14.55 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chrX_-_65253506 14.33 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr3_+_138066539 14.32 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr12_-_6579808 14.31 ENST00000535180.1
ENST00000400911.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr11_-_49230144 14.25 ENST00000343844.4
FOLH1
folate hydrolase (prostate-specific membrane antigen) 1
chr5_-_133706695 14.23 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr11_-_49230184 13.95 ENST00000340334.7
ENST00000256999.2
FOLH1
folate hydrolase (prostate-specific membrane antigen) 1
chr4_-_70826725 13.90 ENST00000353151.3
CSN2
casein beta
chr12_-_3982511 13.76 ENST00000427057.2
ENST00000228820.4
PARP11
poly (ADP-ribose) polymerase family, member 11
chr2_-_27886676 13.74 ENST00000337768.5
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr5_-_41261540 13.70 ENST00000263413.3
C6
complement component 6
chr3_+_67705121 13.69 ENST00000464420.1
ENST00000482677.1
RP11-81N13.1
RP11-81N13.1
chr9_-_110540419 13.61 ENST00000398726.3
AL162389.1
Uncharacterized protein
chr22_-_29949680 13.60 ENST00000397873.2
ENST00000490103.1
THOC5
THO complex 5
chr11_-_47736896 13.50 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2
ATP/GTP binding protein-like 2
chr16_+_70258261 13.49 ENST00000594734.1
FKSG63
FKSG63
chr3_-_122512619 13.47 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr1_+_196788887 13.47 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr4_-_10686475 13.41 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr5_+_54455946 13.26 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr1_+_28099683 13.22 ENST00000373943.4
STX12
syntaxin 12
chr2_+_234959376 13.13 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr22_+_51176624 13.13 ENST00000216139.5
ENST00000529621.1
ACR
acrosin
chr18_-_51750948 13.01 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr6_+_79577189 12.98 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr6_-_90024967 12.98 ENST00000602399.1
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr11_-_35547151 12.97 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr7_-_36764142 12.87 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr9_+_105757590 12.64 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr13_+_21714653 12.26 ENST00000382533.4
SAP18
Sin3A-associated protein, 18kDa
chr11_+_108093839 12.06 ENST00000452508.2
ATM
ataxia telangiectasia mutated
chr1_+_158985457 12.02 ENST00000567661.1
ENST00000474473.1
IFI16
interferon, gamma-inducible protein 16
chr19_+_15852203 11.98 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr8_-_38008783 11.98 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr17_-_64216748 11.88 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr6_+_31105426 11.86 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr13_+_21714711 11.76 ENST00000607003.1
ENST00000492245.1
SAP18
Sin3A-associated protein, 18kDa
chr3_+_35721106 11.58 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr5_-_11589131 11.57 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr12_+_56401268 11.56 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr8_-_86253888 11.40 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr5_+_140552218 11.35 ENST00000231137.3
PCDHB7
protocadherin beta 7
chr20_-_45142154 11.20 ENST00000347606.4
ENST00000457685.2
ZNF334
zinc finger protein 334
chr19_+_42301079 11.19 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr11_-_59633951 10.98 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr6_-_90025011 10.95 ENST00000402938.3
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr1_+_104198377 10.94 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr16_-_66584059 10.94 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr2_+_157330081 10.94 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr1_+_104293028 10.81 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chrX_+_54947229 10.72 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr17_-_34890759 10.56 ENST00000431794.3
MYO19
myosin XIX
chr1_+_26036093 10.49 ENST00000374329.1
MAN1C1
mannosidase, alpha, class 1C, member 1
chr6_-_138539627 10.45 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1
chr9_+_71939488 10.42 ENST00000455972.1
FAM189A2
family with sequence similarity 189, member A2
chr16_-_70239683 10.38 ENST00000601706.1
AC009060.1
Uncharacterized protein
chr16_+_33204156 10.37 ENST00000398667.4
TP53TG3C
TP53 target 3C
chr12_+_74931551 10.37 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chrX_+_77166172 10.31 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr7_-_91509986 10.31 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF
mitochondrial transcription termination factor
chr2_+_211342432 10.29 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr8_-_87755878 10.26 ENST00000320005.5
CNGB3
cyclic nucleotide gated channel beta 3
chr6_+_121756809 10.24 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr5_+_177435986 10.19 ENST00000398106.2
FAM153C
family with sequence similarity 153, member C
chr6_-_154677900 10.05 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr21_+_39644305 10.03 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr22_-_50523760 10.03 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr20_+_58515417 10.03 ENST00000360816.3
FAM217B
family with sequence similarity 217, member B
chr3_+_53528659 9.98 ENST00000350061.5
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr3_-_108836977 9.92 ENST00000232603.5
MORC1
MORC family CW-type zinc finger 1
chr12_-_11463353 9.91 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
PRB4
proline-rich protein BstNI subfamily 4
chr14_+_29241910 9.75 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr10_+_53806501 9.70 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr17_+_7942335 9.64 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
ALOX15B
arachidonate 15-lipoxygenase, type B
chr6_+_127587755 9.48 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146
ring finger protein 146
chr11_-_89540388 9.44 ENST00000532501.2
TRIM49
tripartite motif containing 49
chr17_-_2996290 9.39 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr12_+_111471828 9.38 ENST00000261726.6
CUX2
cut-like homeobox 2
chr15_+_51973680 9.37 ENST00000542355.2
SCG3
secretogranin III
chr12_+_26348246 9.36 ENST00000422622.2
SSPN
sarcospan
chr16_-_28374829 9.31 ENST00000532254.1
NPIPB6
nuclear pore complex interacting protein family, member B6
chr9_-_21368075 9.26 ENST00000449498.1
IFNA13
interferon, alpha 13
chr7_-_73133959 9.10 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A
syntaxin 1A (brain)
chr19_+_36486078 9.03 ENST00000378887.2
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr11_-_49230084 8.97 ENST00000356696.3
FOLH1
folate hydrolase (prostate-specific membrane antigen) 1
chrX_+_8432871 8.93 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
VCX3B
variable charge, X-linked 3B
chr11_-_75917569 8.92 ENST00000322563.3
WNT11
wingless-type MMTV integration site family, member 11
chr3_-_126373929 8.91 ENST00000523403.1
ENST00000524230.2
TXNRD3
thioredoxin reductase 3
chr7_-_18067478 8.91 ENST00000506618.2
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr2_+_89986318 8.72 ENST00000491977.1
IGKV2D-29
immunoglobulin kappa variable 2D-29
chr2_+_132479948 8.72 ENST00000355171.4
C2orf27A
chromosome 2 open reading frame 27A
chr22_-_22337204 8.68 ENST00000430142.1
ENST00000357179.5
TOP3B
topoisomerase (DNA) III beta
chr9_-_5339873 8.56 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chrX_+_10124977 8.55 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr8_-_39695764 8.49 ENST00000265708.4
ADAM2
ADAM metallopeptidase domain 2
chr4_+_106473768 8.49 ENST00000265154.2
ENST00000420470.2
ARHGEF38
Rho guanine nucleotide exchange factor (GEF) 38
chr8_-_66474884 8.47 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr11_-_35440796 8.33 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_+_106534192 8.33 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr12_+_81471816 8.32 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr6_+_29426230 8.32 ENST00000442615.1
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr4_+_154125565 8.32 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr9_-_5304432 8.26 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr7_-_14942283 8.23 ENST00000402815.1
DGKB
diacylglycerol kinase, beta 90kDa
chr10_+_95517660 8.19 ENST00000371413.3
LGI1
leucine-rich, glioma inactivated 1
chr2_+_103035102 8.18 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr12_-_123450986 8.18 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr19_+_54466179 8.16 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr11_+_55029628 8.13 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr1_+_117297007 8.05 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr1_+_111773349 8.01 ENST00000533831.2
CHI3L2
chitinase 3-like 2
chr6_+_27833034 7.99 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr1_+_196743912 7.89 ENST00000367425.4
CFHR3
complement factor H-related 3
chr12_-_51718436 7.88 ENST00000544402.1
BIN2
bridging integrator 2
chr8_-_86290333 7.80 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr13_-_36920420 7.72 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr8_+_104892639 7.65 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr4_+_159131630 7.60 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr2_-_62733476 7.58 ENST00000335390.5
TMEM17
transmembrane protein 17
chr10_+_114135952 7.57 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_51549498 7.56 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chrY_-_19992098 7.51 ENST00000544303.1
ENST00000382867.3
CDY2B
chromodomain protein, Y-linked, 2B
chr19_+_48774586 7.51 ENST00000594024.1
ENST00000595408.1
ENST00000315849.1
ZNF114
zinc finger protein 114
chr8_+_77593448 7.44 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr2_-_89310012 7.44 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr1_+_13910479 7.42 ENST00000509009.1
PDPN
podoplanin
chr11_+_113185292 7.37 ENST00000429951.1
ENST00000442859.1
ENST00000531164.1
ENST00000529850.1
ENST00000314756.3
ENST00000525965.1
TTC12
tetratricopeptide repeat domain 12
chr3_-_10452359 7.34 ENST00000452124.1
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
14.0 42.1 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
9.6 19.3 GO:0044782 cilium organization(GO:0044782)
9.4 28.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
9.0 36.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
7.8 23.4 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
7.6 91.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
7.4 22.2 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
7.3 21.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
6.3 50.7 GO:0035608 protein deglutamylation(GO:0035608)
4.9 29.5 GO:0090131 mesenchyme migration(GO:0090131)
4.6 13.9 GO:1903487 regulation of lactation(GO:1903487)
4.6 45.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
4.1 28.5 GO:0007341 penetration of zona pellucida(GO:0007341)
4.0 12.1 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
4.0 56.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
4.0 12.0 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
3.7 18.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
3.4 10.3 GO:0071284 cellular response to lead ion(GO:0071284)
3.4 13.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
3.3 19.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
3.2 19.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
3.0 21.1 GO:0044245 polysaccharide digestion(GO:0044245)
3.0 14.9 GO:0036369 transcription factor catabolic process(GO:0036369)
3.0 8.9 GO:0060775 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
2.8 36.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
2.7 10.9 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
2.6 10.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
2.5 35.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
2.4 36.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
2.4 14.6 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
2.3 6.9 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
2.3 9.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
2.3 22.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.2 10.9 GO:0006127 glycerophosphate shuttle(GO:0006127)
2.1 21.5 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
2.1 6.4 GO:1990502 dense core granule maturation(GO:1990502)
2.0 12.1 GO:0034201 response to oleic acid(GO:0034201)
2.0 9.9 GO:0044026 DNA hypermethylation(GO:0044026)
1.9 15.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.9 7.7 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
1.8 5.5 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.8 7.3 GO:0021633 optic nerve structural organization(GO:0021633)
1.8 18.2 GO:0015889 cobalamin transport(GO:0015889)
1.8 8.9 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
1.7 10.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
1.7 5.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
1.7 11.7 GO:0048014 Tie signaling pathway(GO:0048014)
1.7 5.0 GO:0021631 optic nerve morphogenesis(GO:0021631) positive regulation of long-term neuronal synaptic plasticity(GO:0048170) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
1.7 8.3 GO:0033078 extrathymic T cell differentiation(GO:0033078)
1.7 10.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
1.7 19.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.6 8.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
1.6 9.6 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.6 3.2 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
1.5 15.0 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.5 45.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
1.4 14.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.4 17.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.4 4.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.4 5.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
1.4 23.4 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.4 13.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.4 6.8 GO:0006311 meiotic gene conversion(GO:0006311) male meiosis chromosome segregation(GO:0007060)
1.3 5.3 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
1.3 17.1 GO:0070327 thyroid hormone transport(GO:0070327)
1.2 5.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.2 19.5 GO:0071285 cellular response to lithium ion(GO:0071285)
1.2 18.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
1.2 7.1 GO:0001714 endodermal cell fate specification(GO:0001714)
1.2 3.6 GO:0009726 detection of endogenous stimulus(GO:0009726)
1.1 21.5 GO:0035493 SNARE complex assembly(GO:0035493)
1.1 6.6 GO:0002933 lipid hydroxylation(GO:0002933)
1.1 3.2 GO:0002215 defense response to nematode(GO:0002215)
1.1 4.3 GO:0070245 snRNA transcription from RNA polymerase III promoter(GO:0042796) positive regulation of thymocyte apoptotic process(GO:0070245)
1.0 9.2 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
1.0 9.7 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
1.0 21.9 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.9 14.9 GO:0045792 negative regulation of cell size(GO:0045792)
0.9 46.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.9 2.7 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.9 8.0 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.9 17.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 18.2 GO:0036315 cellular response to sterol(GO:0036315)
0.8 2.5 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.8 13.0 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.8 6.4 GO:0002118 aggressive behavior(GO:0002118)
0.8 3.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.8 3.9 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.8 10.0 GO:0015671 oxygen transport(GO:0015671)
0.8 4.6 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.7 4.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.7 16.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.7 2.8 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908)
0.7 0.7 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.7 1.4 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.7 8.7 GO:0006265 DNA topological change(GO:0006265)
0.7 14.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.7 0.7 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.7 2.6 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.6 3.7 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.6 7.8 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.6 31.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.6 5.9 GO:0034465 response to carbon monoxide(GO:0034465) smooth muscle contraction involved in micturition(GO:0060083)
0.6 5.9 GO:1904424 regulation of GTP binding(GO:1904424)
0.6 6.4 GO:0070307 lens fiber cell development(GO:0070307)
0.6 24.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.6 17.0 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.6 25.6 GO:0010107 potassium ion import(GO:0010107)
0.6 9.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.6 5.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.6 4.4 GO:0055091 phospholipid homeostasis(GO:0055091)
0.5 16.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 29.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.5 7.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.5 9.4 GO:0007614 short-term memory(GO:0007614)
0.5 3.7 GO:0015886 heme transport(GO:0015886)
0.5 7.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.4 8.2 GO:0097320 membrane tubulation(GO:0097320)
0.4 8.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.4 14.2 GO:0097484 dendrite extension(GO:0097484)
0.4 15.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 16.9 GO:0033344 cholesterol efflux(GO:0033344)
0.4 3.5 GO:1901898 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 3.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.4 6.9 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.4 5.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.4 4.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 2.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 1.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.3 2.0 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.3 12.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.3 1.9 GO:0001570 vasculogenesis(GO:0001570)
0.3 1.0 GO:1900157 hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of osteoclast proliferation(GO:0090290) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 25.6 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 15.3 GO:0015701 bicarbonate transport(GO:0015701)
0.3 5.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 4.8 GO:0051775 response to redox state(GO:0051775)
0.3 6.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 1.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 4.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 4.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.3 6.7 GO:0097503 sialylation(GO:0097503)
0.3 3.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 4.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 4.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.2 7.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.2 6.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 2.8 GO:0006108 malate metabolic process(GO:0006108)
0.2 4.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.2 2.3 GO:0007097 nuclear migration(GO:0007097)
0.2 1.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 1.3 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826) interleukin-33-mediated signaling pathway(GO:0038172)
0.2 9.0 GO:0000305 response to oxygen radical(GO:0000305)
0.2 29.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.2 7.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 4.9 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 0.9 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 2.3 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.2 6.3 GO:0007050 cell cycle arrest(GO:0007050)
0.2 5.9 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2 6.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 3.5 GO:0030220 platelet formation(GO:0030220)
0.2 0.9 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.2 4.3 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.2 1.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 2.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 10.0 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 6.5 GO:0001895 retina homeostasis(GO:0001895)
0.1 5.6 GO:0015914 phospholipid transport(GO:0015914)
0.1 17.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 2.4 GO:0006465 signal peptide processing(GO:0006465)
0.1 6.0 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 6.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 8.3 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.1 15.6 GO:0002377 immunoglobulin production(GO:0002377)
0.1 8.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.8 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 4.1 GO:0014047 glutamate secretion(GO:0014047)
0.1 5.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 6.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 14.9 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 11.6 GO:0034605 cellular response to heat(GO:0034605)
0.1 4.5 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 10.1 GO:0007605 sensory perception of sound(GO:0007605)
0.1 1.7 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1 5.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 6.2 GO:0046849 bone remodeling(GO:0046849)
0.1 9.3 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 1.5 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 3.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.4 GO:0048240 sperm capacitation(GO:0048240)
0.1 3.4 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.1 5.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 1.1 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 7.7 GO:0007224 smoothened signaling pathway(GO:0007224)
0.1 7.3 GO:0050900 leukocyte migration(GO:0050900)
0.1 0.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 6.2 GO:0007586 digestion(GO:0007586)
0.1 1.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.6 GO:0007267 cell-cell signaling(GO:0007267)
0.1 1.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 7.9 GO:0050808 synapse organization(GO:0050808)
0.0 3.0 GO:0006968 cellular defense response(GO:0006968)
0.0 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 3.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 8.9 GO:0006935 chemotaxis(GO:0006935) taxis(GO:0042330)
0.0 3.7 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 5.9 GO:0007565 female pregnancy(GO:0007565)
0.0 0.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 7.9 GO:0001558 regulation of cell growth(GO:0001558)
0.0 8.3 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 3.2 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.4 GO:0019048 modulation by virus of host morphology or physiology(GO:0019048)
0.0 3.4 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 1.2 GO:0000209 protein polyubiquitination(GO:0000209)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
14.0 42.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
7.4 29.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
6.5 91.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
6.3 12.6 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
4.4 13.1 GO:0043159 acrosomal matrix(GO:0043159)
3.9 19.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
2.3 9.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
2.2 22.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
2.1 6.2 GO:0097679 other organism cytoplasm(GO:0097679)
2.0 36.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.9 17.2 GO:0005579 membrane attack complex(GO:0005579)
1.8 10.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.8 32.8 GO:0031089 platelet dense granule lumen(GO:0031089)
1.7 12.0 GO:0030061 mitochondrial crista(GO:0030061)
1.4 6.8 GO:0000801 central element(GO:0000801)
1.3 37.2 GO:0034451 centriolar satellite(GO:0034451)
1.2 9.3 GO:0030914 STAGA complex(GO:0030914)
1.2 15.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.0 54.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.9 20.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.8 21.9 GO:0071437 invadopodium(GO:0071437)
0.8 3.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.8 13.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.7 5.9 GO:0000322 storage vacuole(GO:0000322)
0.7 24.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.7 10.2 GO:0005916 fascia adherens(GO:0005916)
0.6 7.6 GO:0036038 MKS complex(GO:0036038)
0.6 21.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.6 7.3 GO:0033010 paranodal junction(GO:0033010)
0.6 30.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.6 27.5 GO:0048786 presynaptic active zone(GO:0048786)
0.6 48.5 GO:0005811 lipid particle(GO:0005811)
0.6 15.5 GO:0030673 axolemma(GO:0030673)
0.5 6.4 GO:0005577 fibrinogen complex(GO:0005577)
0.5 3.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.5 16.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.5 12.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.5 6.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.4 21.5 GO:0031201 SNARE complex(GO:0031201)
0.4 16.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4 2.0 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.4 3.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.4 79.6 GO:0072562 blood microparticle(GO:0072562)
0.4 55.5 GO:0043204 perikaryon(GO:0043204)
0.4 33.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.4 12.1 GO:1990391 DNA repair complex(GO:1990391)
0.3 2.4 GO:0005787 signal peptidase complex(GO:0005787)
0.3 2.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3 0.9 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.3 12.9 GO:0009925 basal plasma membrane(GO:0009925)
0.3 1.7 GO:0002177 manchette(GO:0002177)
0.3 3.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 6.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 19.2 GO:0035580 specific granule lumen(GO:0035580)
0.2 20.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 5.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 13.8 GO:0005643 nuclear pore(GO:0005643)
0.2 3.9 GO:0012505 endomembrane system(GO:0012505)
0.2 6.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 8.3 GO:0036477 somatodendritic compartment(GO:0036477)
0.2 1.4 GO:0016324 apical plasma membrane(GO:0016324)
0.2 18.4 GO:0035579 specific granule membrane(GO:0035579)
0.2 6.9 GO:0008305 integrin complex(GO:0008305)
0.2 2.3 GO:0005869 dynactin complex(GO:0005869)
0.2 49.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 2.6 GO:0001891 phagocytic cup(GO:0001891)
0.2 52.7 GO:0019898 extrinsic component of membrane(GO:0019898)
0.2 16.9 GO:0005814 centriole(GO:0005814)
0.2 4.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 7.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 10.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.7 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 12.2 GO:0031902 late endosome membrane(GO:0031902)
0.1 3.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 2.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 5.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 4.9 GO:0043195 terminal bouton(GO:0043195)
0.1 14.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 7.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 6.4 GO:0005882 intermediate filament(GO:0005882)
0.1 6.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 7.5 GO:0005884 actin filament(GO:0005884)
0.1 83.1 GO:0005615 extracellular space(GO:0005615)
0.1 4.1 GO:0042383 sarcolemma(GO:0042383)
0.1 0.5 GO:0044297 cell body(GO:0044297)
0.1 12.3 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 3.3 GO:0016459 myosin complex(GO:0016459)
0.0 5.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 5.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 4.2 GO:0055037 recycling endosome(GO:0055037)
0.0 9.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 2.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.0 42.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
9.3 37.2 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
8.8 35.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
8.0 32.0 GO:0016160 amylase activity(GO:0016160)
7.3 21.8 GO:0035473 lipase binding(GO:0035473)
4.9 19.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
4.7 28.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
4.4 13.1 GO:0004040 amidase activity(GO:0004040) fucose binding(GO:0042806)
4.3 12.9 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
4.2 25.5 GO:0003998 acylphosphatase activity(GO:0003998)
4.0 12.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
3.7 22.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
3.6 10.9 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
3.6 7.2 GO:0015235 cobalamin transporter activity(GO:0015235)
3.4 10.3 GO:0032767 copper-dependent protein binding(GO:0032767)
3.1 37.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.0 14.9 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
2.8 14.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.7 10.9 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
2.7 8.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
2.4 19.2 GO:0004064 arylesterase activity(GO:0004064)
2.3 6.9 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
2.2 6.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
2.2 15.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
2.1 6.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
2.0 41.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
2.0 12.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
2.0 36.1 GO:0001054 RNA polymerase I activity(GO:0001054)
1.9 9.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
1.9 22.4 GO:0032027 myosin light chain binding(GO:0032027)
1.8 22.2 GO:0008517 folic acid transporter activity(GO:0008517)
1.8 9.2 GO:0061665 SUMO ligase activity(GO:0061665)
1.8 5.5 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
1.8 16.3 GO:0032051 clathrin light chain binding(GO:0032051)
1.7 17.1 GO:0070324 thyroid hormone binding(GO:0070324)
1.7 10.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
1.5 4.6 GO:0046848 hydroxyapatite binding(GO:0046848)
1.5 8.9 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.5 5.9 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
1.5 4.4 GO:0017129 triglyceride binding(GO:0017129)
1.5 10.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
1.5 23.4 GO:0015643 toxic substance binding(GO:0015643)
1.4 8.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
1.4 25.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.4 36.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.4 5.5 GO:0031716 calcitonin receptor binding(GO:0031716)
1.3 5.3 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
1.3 13.0 GO:0003696 satellite DNA binding(GO:0003696)
1.2 11.0 GO:0031419 cobalamin binding(GO:0031419)
1.2 6.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.2 3.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
1.2 8.2 GO:0008142 oxysterol binding(GO:0008142)
1.1 6.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.0 62.2 GO:0004601 peroxidase activity(GO:0004601)
1.0 75.3 GO:0050840 extracellular matrix binding(GO:0050840)
1.0 10.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
1.0 43.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.9 46.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.9 8.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.9 15.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.8 5.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.8 12.0 GO:0017127 cholesterol transporter activity(GO:0017127)
0.8 18.2 GO:0071949 FAD binding(GO:0071949)
0.8 3.2 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.7 8.0 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.7 4.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.7 24.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.7 6.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 7.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.6 5.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.6 5.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.6 6.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.5 15.0 GO:0005521 lamin binding(GO:0005521)
0.5 19.5 GO:0005504 fatty acid binding(GO:0005504)
0.5 8.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.5 14.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.5 6.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.5 5.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.5 8.5 GO:0070330 aromatase activity(GO:0070330)
0.5 2.5 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.5 6.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.5 15.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 4.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.5 3.7 GO:0015232 heme transporter activity(GO:0015232)
0.5 4.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.5 11.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645)
0.4 47.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 7.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.4 1.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 8.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.4 8.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4 2.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.4 5.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 18.4 GO:0008009 chemokine activity(GO:0008009)
0.3 0.7 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.3 33.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 4.3 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.3 7.1 GO:0035198 miRNA binding(GO:0035198)
0.3 9.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 7.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.3 14.9 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.3 19.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.3 11.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 1.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 4.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 14.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 8.9 GO:0005109 frizzled binding(GO:0005109)
0.2 8.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 2.8 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.2 23.6 GO:0008013 beta-catenin binding(GO:0008013)
0.2 2.8 GO:0035240 dopamine binding(GO:0035240)
0.2 20.0 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.2 4.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 3.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 4.7 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.2 9.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 3.0 GO:0031005 filamin binding(GO:0031005)
0.2 4.5 GO:0031489 myosin V binding(GO:0031489)
0.2 14.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 12.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.2 2.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 0.4 GO:0033149 FFAT motif binding(GO:0033149)
0.1 3.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 16.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 7.0 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 1.0 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 14.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 15.3 GO:0005179 hormone activity(GO:0005179)
0.1 18.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 12.6 GO:0005319 lipid transporter activity(GO:0005319)
0.1 3.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 4.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 2.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.4 GO:0003924 GTPase activity(GO:0003924)
0.1 16.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.6 GO:0005537 mannose binding(GO:0005537)
0.1 59.4 GO:0005509 calcium ion binding(GO:0005509)
0.1 10.0 GO:0008565 protein transporter activity(GO:0008565)
0.1 2.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 16.9 GO:0003823 antigen binding(GO:0003823)
0.1 1.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 10.2 GO:0030674 protein binding, bridging(GO:0030674)
0.1 43.7 GO:0008270 zinc ion binding(GO:0008270)
0.1 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 9.6 GO:0008083 growth factor activity(GO:0008083)
0.0 4.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.8 GO:0002020 protease binding(GO:0002020)
0.0 3.7 GO:0046332 SMAD binding(GO:0046332)
0.0 4.3 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 6.3 GO:0051020 GTPase binding(GO:0051020)
0.0 0.9 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 5.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 21.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.5 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 99.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.8 34.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.7 17.7 PID CONE PATHWAY Visual signal transduction: Cones
0.5 38.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 87.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.4 94.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 24.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.3 10.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 14.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.3 5.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.3 18.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3 12.0 PID SHP2 PATHWAY SHP2 signaling
0.3 15.1 PID IL23 PATHWAY IL23-mediated signaling events
0.2 15.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 24.4 PID CMYB PATHWAY C-MYB transcription factor network
0.2 39.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 31.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 5.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 4.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 13.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 9.3 PID MYC PATHWAY C-MYC pathway
0.2 10.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 3.9 PID IFNG PATHWAY IFN-gamma pathway
0.2 12.1 PID ATM PATHWAY ATM pathway
0.2 6.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 14.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 7.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 9.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 4.5 PID BCR 5PATHWAY BCR signaling pathway
0.2 6.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 6.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 4.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 8.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 4.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 37.0 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 5.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 5.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 41.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
3.4 91.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
3.3 13.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
2.9 73.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.7 33.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.6 43.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
1.1 15.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
1.0 15.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
1.0 40.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.9 47.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.9 12.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.8 25.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.7 17.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.7 19.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.6 24.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.6 10.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.5 7.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.5 31.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.5 18.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.5 5.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 15.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.4 7.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 18.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 12.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 6.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 3.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 10.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 4.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 4.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 4.7 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.3 18.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 15.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 5.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 6.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.3 5.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 12.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 8.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 9.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 6.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 10.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 15.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 6.4 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.1 2.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 7.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 3.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 7.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 1.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 8.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 8.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 16.6 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 2.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation