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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for CXXC1

Z-value: 1.56

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Transcription factors associated with CXXC1

Gene Symbol Gene ID Gene Info
CXXC1
ENSG00000154832.10 CXXC finger protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CXXC1hg19_v2_chr18_-_47813940_478140210.187.2e-03Click!

Activity profile of CXXC1 motif

Sorted Z-values of CXXC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_80942139 55.82 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
MRPS28
mitochondrial ribosomal protein S28
chr8_-_80942467 54.52 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
MRPS28
mitochondrial ribosomal protein S28
chr7_+_26241325 54.39 ENST00000456948.1
ENST00000409747.1
CBX3
chromobox homolog 3
chrX_+_23685653 52.34 ENST00000379331.3
PRDX4
peroxiredoxin 4
chr4_-_174255536 49.84 ENST00000446922.2
HMGB2
high mobility group box 2
chr11_+_32605350 49.83 ENST00000531120.1
ENST00000524896.1
ENST00000323213.5
EIF3M
eukaryotic translation initiation factor 3, subunit M
chr5_+_95998746 49.49 ENST00000508608.1
CAST
calpastatin
chr1_+_40723779 48.96 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr3_-_185641681 48.39 ENST00000259043.7
TRA2B
transformer 2 beta homolog (Drosophila)
chr17_-_8113886 47.94 ENST00000577833.1
ENST00000534871.1
ENST00000583915.1
ENST00000316199.6
ENST00000581511.1
ENST00000585124.1
AURKB
aurora kinase B
chr16_-_66864806 44.98 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr12_+_95867919 44.79 ENST00000261220.9
ENST00000549502.1
ENST00000553151.1
ENST00000550777.1
ENST00000551840.1
METAP2
methionyl aminopeptidase 2
chr3_+_127323739 44.03 ENST00000491422.1
MCM2
minichromosome maintenance complex component 2
chr8_-_80942061 43.53 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr5_+_68462944 43.44 ENST00000506572.1
CCNB1
cyclin B1
chr1_+_84944926 42.40 ENST00000370656.1
ENST00000370654.5
RPF1
ribosome production factor 1 homolog (S. cerevisiae)
chr13_+_43597269 42.28 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chrX_+_23685563 42.05 ENST00000379341.4
PRDX4
peroxiredoxin 4
chr5_+_68463043 40.37 ENST00000508407.1
ENST00000505500.1
CCNB1
cyclin B1
chr1_-_151162606 40.10 ENST00000354473.4
ENST00000368892.4
VPS72
vacuolar protein sorting 72 homolog (S. cerevisiae)
chr15_-_91537723 38.59 ENST00000394249.3
ENST00000559811.1
ENST00000442656.2
ENST00000557905.1
ENST00000361919.3
PRC1
protein regulator of cytokinesis 1
chr1_-_225616515 37.91 ENST00000338179.2
ENST00000425080.1
LBR
lamin B receptor
chr20_+_3190006 37.43 ENST00000380113.3
ENST00000455664.2
ENST00000399838.3
ITPA
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr1_+_165864821 37.42 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr17_-_73149921 37.30 ENST00000481647.1
ENST00000470924.1
HN1
hematological and neurological expressed 1
chr11_-_88070920 36.36 ENST00000524463.1
ENST00000227266.5
CTSC
cathepsin C
chr1_-_67896009 36.25 ENST00000370990.5
SERBP1
SERPINE1 mRNA binding protein 1
chr19_-_44031375 35.80 ENST00000292147.2
ETHE1
ethylmalonic encephalopathy 1
chr3_-_146262428 35.26 ENST00000486631.1
PLSCR1
phospholipid scramblase 1
chr12_+_104359576 34.70 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr10_+_51572339 34.57 ENST00000344348.6
NCOA4
nuclear receptor coactivator 4
chr8_-_71520513 34.45 ENST00000262213.2
ENST00000536748.1
ENST00000518678.1
TRAM1
translocation associated membrane protein 1
chr19_-_44031341 33.92 ENST00000600651.1
ETHE1
ethylmalonic encephalopathy 1
chr9_+_133710453 32.91 ENST00000318560.5
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr16_+_88923494 32.71 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
TRAPPC2L
trafficking protein particle complex 2-like
chr10_+_51572408 32.45 ENST00000374082.1
NCOA4
nuclear receptor coactivator 4
chr1_-_67896095 32.05 ENST00000370994.4
SERBP1
SERPINE1 mRNA binding protein 1
chr11_-_14665163 31.86 ENST00000418988.2
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr17_+_73201754 31.86 ENST00000583569.1
ENST00000245544.4
ENST00000579324.1
ENST00000541827.1
ENST00000579298.1
ENST00000447371.2
NUP85
nucleoporin 85kDa
chr3_-_185542761 31.70 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr10_+_76969909 31.48 ENST00000298468.5
ENST00000543351.1
VDAC2
voltage-dependent anion channel 2
chr1_+_165864800 31.47 ENST00000469256.2
UCK2
uridine-cytidine kinase 2
chr22_+_40742497 31.43 ENST00000216194.7
ADSL
adenylosuccinate lyase
chr1_-_222885770 31.28 ENST00000355727.2
ENST00000340020.6
AIDA
axin interactor, dorsalization associated
chr17_-_8113542 31.27 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB
aurora kinase B
chr7_+_141438393 31.25 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
SSBP1
single-stranded DNA binding protein 1, mitochondrial
chr12_+_104359641 31.23 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr2_-_44223138 31.08 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chrX_+_77359726 30.96 ENST00000442431.1
PGK1
phosphoglycerate kinase 1
chrX_+_48433326 30.60 ENST00000376755.1
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr10_+_124913930 30.59 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr1_-_67896069 30.34 ENST00000370995.2
ENST00000361219.6
SERBP1
SERPINE1 mRNA binding protein 1
chr6_+_13615554 30.32 ENST00000451315.2
NOL7
nucleolar protein 7, 27kDa
chr11_-_47664072 30.17 ENST00000542981.1
ENST00000530428.1
ENST00000302503.3
MTCH2
mitochondrial carrier 2
chr1_+_45212074 29.98 ENST00000372217.1
KIF2C
kinesin family member 2C
chr17_-_73150599 29.90 ENST00000392566.2
ENST00000581874.1
HN1
hematological and neurological expressed 1
chr2_+_171785012 29.82 ENST00000234160.4
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr18_+_3449695 29.29 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr1_+_113161778 29.20 ENST00000263168.3
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr1_+_214776516 29.12 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr6_+_138725343 29.11 ENST00000607197.1
ENST00000367697.3
HEBP2
heme binding protein 2
chr2_+_113403434 29.03 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr1_-_153950116 28.94 ENST00000368589.1
JTB
jumping translocation breakpoint
chr18_+_3449821 28.44 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr15_-_55489097 28.31 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr12_-_31479045 27.84 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr7_+_12727250 27.83 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr13_+_100153665 27.77 ENST00000376387.4
TM9SF2
transmembrane 9 superfamily member 2
chrX_+_77359671 27.60 ENST00000373316.4
PGK1
phosphoglycerate kinase 1
chr16_-_2301563 27.51 ENST00000562238.1
ENST00000566379.1
ENST00000301729.4
ECI1
enoyl-CoA delta isomerase 1
chr1_-_40042416 27.32 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr12_+_4430371 27.25 ENST00000179259.4
C12orf5
chromosome 12 open reading frame 5
chr19_+_12917364 27.11 ENST00000221486.4
RNASEH2A
ribonuclease H2, subunit A
chr19_-_13044494 26.87 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr19_-_2050852 26.79 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr11_-_64013663 26.77 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_-_185542817 26.70 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_28562617 26.60 ENST00000497986.1
ENST00000335514.5
ENST00000468425.2
ENST00000465645.1
ATPIF1
ATPase inhibitory factor 1
chr6_+_57037089 26.55 ENST00000370693.5
BAG2
BCL2-associated athanogene 2
chr11_-_14541872 26.39 ENST00000419365.2
ENST00000530457.1
ENST00000532256.1
ENST00000533068.1
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr5_-_86708670 26.35 ENST00000504878.1
CCNH
cyclin H
chr7_+_116166331 26.33 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr2_+_75061108 26.32 ENST00000290573.2
HK2
hexokinase 2
chr12_-_49075941 26.32 ENST00000553086.1
ENST00000548304.1
KANSL2
KAT8 regulatory NSL complex subunit 2
chr12_-_110883346 26.28 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr1_+_236558694 26.20 ENST00000359362.5
EDARADD
EDAR-associated death domain
chr9_+_114423615 26.19 ENST00000374293.4
GNG10
guanine nucleotide binding protein (G protein), gamma 10
chr19_+_16178317 26.17 ENST00000344824.6
ENST00000538887.1
TPM4
tropomyosin 4
chrX_-_109561294 26.08 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr7_+_87505544 25.92 ENST00000265728.1
DBF4
DBF4 homolog (S. cerevisiae)
chr11_+_10772534 25.68 ENST00000361367.2
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr15_-_64455404 25.63 ENST00000300026.3
PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr2_-_55496344 25.51 ENST00000403721.1
ENST00000263629.4
MTIF2
mitochondrial translational initiation factor 2
chr12_+_118454500 25.47 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
RFC5
replication factor C (activator 1) 5, 36.5kDa
chr1_+_29063271 25.19 ENST00000373812.3
YTHDF2
YTH domain family, member 2
chr5_-_37371278 25.17 ENST00000231498.3
NUP155
nucleoporin 155kDa
chr3_+_127317066 25.08 ENST00000265056.7
MCM2
minichromosome maintenance complex component 2
chr2_-_150444116 24.88 ENST00000428879.1
ENST00000422782.2
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr1_+_228270784 24.86 ENST00000541182.1
ARF1
ADP-ribosylation factor 1
chr3_-_10362725 24.72 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13
SEC13 homolog (S. cerevisiae)
chr4_-_7069760 24.70 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr1_-_244615425 24.69 ENST00000366535.3
ADSS
adenylosuccinate synthase
chrX_+_153991025 24.67 ENST00000369550.5
DKC1
dyskeratosis congenita 1, dyskerin
chr2_-_152684977 24.64 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr18_+_3451646 24.42 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr5_+_112196919 24.41 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
SRP19
signal recognition particle 19kDa
chr7_+_116139744 24.40 ENST00000343213.2
CAV2
caveolin 2
chr7_+_23221438 24.20 ENST00000258742.5
NUPL2
nucleoporin like 2
chr1_+_179050512 24.00 ENST00000367627.3
TOR3A
torsin family 3, member A
chr6_-_138428613 23.99 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr8_-_21999447 23.83 ENST00000306306.3
ENST00000521744.1
REEP4
receptor accessory protein 4
chr1_-_153949751 23.82 ENST00000428469.1
JTB
jumping translocation breakpoint
chr1_-_211752073 23.79 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr8_-_17104356 23.76 ENST00000361272.4
ENST00000523917.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr8_+_145149930 23.71 ENST00000318911.4
CYC1
cytochrome c-1
chr1_+_11072696 23.67 ENST00000240185.3
ENST00000476201.1
TARDBP
TAR DNA binding protein
chr12_-_57081940 23.65 ENST00000436399.2
PTGES3
prostaglandin E synthase 3 (cytosolic)
chr15_+_89787180 23.63 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
FANCI
Fanconi anemia, complementation group I
chr18_+_12703002 23.56 ENST00000590217.1
PSMG2
proteasome (prosome, macropain) assembly chaperone 2
chr3_-_146262365 23.49 ENST00000448787.2
PLSCR1
phospholipid scramblase 1
chr5_-_96518907 23.49 ENST00000508447.1
ENST00000283109.3
RIOK2
RIO kinase 2
chr17_-_40075197 23.47 ENST00000590770.1
ENST00000590151.1
ACLY
ATP citrate lyase
chr8_-_48872686 23.47 ENST00000314191.2
ENST00000338368.3
PRKDC
protein kinase, DNA-activated, catalytic polypeptide
chr7_-_7680601 23.33 ENST00000396682.2
RPA3
replication protein A3, 14kDa
chr7_-_26240357 23.24 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr8_+_38854418 23.18 ENST00000481513.1
ENST00000487273.2
ADAM9
ADAM metallopeptidase domain 9
chr5_-_86708833 23.15 ENST00000256897.4
CCNH
cyclin H
chr3_+_23847394 23.08 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chrX_-_107334790 23.04 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr12_+_27863706 23.02 ENST00000081029.3
ENST00000538315.1
ENST00000542791.1
MRPS35
mitochondrial ribosomal protein S35
chr5_+_115177178 22.97 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr3_-_146262293 22.94 ENST00000448205.1
PLSCR1
phospholipid scramblase 1
chr8_-_80993010 22.85 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr2_+_65454926 22.55 ENST00000542850.1
ENST00000377982.4
ACTR2
ARP2 actin-related protein 2 homolog (yeast)
chr2_+_136499287 22.55 ENST00000415164.1
UBXN4
UBX domain protein 4
chr3_-_146262352 22.55 ENST00000462666.1
PLSCR1
phospholipid scramblase 1
chr14_+_35591928 22.49 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chr2_+_235860616 22.49 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr2_+_187350883 22.44 ENST00000337859.6
ZC3H15
zinc finger CCCH-type containing 15
chr1_-_63988846 22.38 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr11_+_70049269 22.36 ENST00000301838.4
FADD
Fas (TNFRSF6)-associated via death domain
chr1_+_231664390 22.34 ENST00000366639.4
ENST00000413309.2
TSNAX
translin-associated factor X
chr3_-_146262488 22.19 ENST00000487389.1
PLSCR1
phospholipid scramblase 1
chr2_-_209119831 22.13 ENST00000345146.2
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr1_+_151372010 22.13 ENST00000290541.6
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr12_-_6451186 22.11 ENST00000540022.1
ENST00000536194.1
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr8_+_145582217 21.91 ENST00000530047.1
ENST00000527078.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr7_+_102937869 21.90 ENST00000249269.4
ENST00000428154.1
ENST00000420236.2
PMPCB
peptidase (mitochondrial processing) beta
chr21_-_26979786 21.88 ENST00000419219.1
ENST00000352957.4
ENST00000307301.7
MRPL39
mitochondrial ribosomal protein L39
chr2_+_86333301 21.84 ENST00000254630.7
PTCD3
pentatricopeptide repeat domain 3
chr6_-_159065741 21.81 ENST00000367085.3
ENST00000367089.3
DYNLT1
dynein, light chain, Tctex-type 1
chr12_+_104359614 21.79 ENST00000266775.9
ENST00000544861.1
TDG
thymine-DNA glycosylase
chr1_+_149822620 21.73 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr7_-_105752971 21.49 ENST00000011473.2
SYPL1
synaptophysin-like 1
chr2_+_198365122 21.45 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr14_-_102552659 21.40 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr11_+_60609537 21.39 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr11_+_65769550 21.38 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
BANF1
barrier to autointegration factor 1
chr5_-_77072145 21.35 ENST00000380377.4
TBCA
tubulin folding cofactor A
chr18_+_3451584 21.30 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr12_+_75874460 21.29 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr6_+_134274322 21.28 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr2_-_169769787 21.27 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr1_-_153950098 21.20 ENST00000356648.1
JTB
jumping translocation breakpoint
chr17_+_39846114 21.07 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr5_+_34915444 21.04 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr2_-_70520539 20.97 ENST00000482975.2
ENST00000438261.1
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr2_-_70520832 20.89 ENST00000454893.1
ENST00000272348.2
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr14_+_35761580 20.87 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chrX_-_114953669 20.87 ENST00000449327.1
RP1-241P17.4
Uncharacterized protein
chr10_+_124913793 20.81 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chr11_-_6633799 20.73 ENST00000299424.4
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr19_+_36236491 20.60 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr6_-_5261141 20.57 ENST00000330636.4
ENST00000500576.2
LYRM4
LYR motif containing 4
chr2_-_106015527 20.54 ENST00000344213.4
ENST00000358129.4
FHL2
four and a half LIM domains 2
chr17_+_49243792 20.50 ENST00000393183.3
ENST00000393190.1
NME1-NME2
NME1-NME2 readthrough
chr19_+_41770978 20.48 ENST00000593587.1
ENST00000263367.3
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr2_-_37899323 20.48 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr7_-_25164969 20.48 ENST00000305786.2
CYCS
cytochrome c, somatic
chr2_+_216176761 20.48 ENST00000540518.1
ENST00000435675.1
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr8_-_21999362 20.47 ENST00000334530.5
ENST00000518664.1
REEP4
receptor accessory protein 4
chr16_-_85722530 20.31 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr1_-_40042073 20.29 ENST00000372858.3
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr13_+_53029564 20.27 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
CKAP2
cytoskeleton associated protein 2
chr7_-_6523755 20.20 ENST00000436575.1
ENST00000258739.4
DAGLB
KDELR2
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr3_+_160117418 20.15 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chr12_-_120638902 19.93 ENST00000551150.1
ENST00000313104.5
ENST00000547191.1
ENST00000546989.1
ENST00000392514.4
ENST00000228306.4
ENST00000550856.1
RPLP0
ribosomal protein, large, P0
chr1_-_45988542 19.85 ENST00000424390.1
PRDX1
peroxiredoxin 1
chr9_+_112542591 19.83 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr14_+_73563735 19.81 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr3_-_149095652 19.81 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr4_+_57845043 19.79 ENST00000433463.1
ENST00000314595.5
POLR2B
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr6_-_31774714 19.69 ENST00000375661.5
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_3622893 19.52 ENST00000407445.3
ENST00000403564.1
RPS7
ribosomal protein S7
chr2_+_120124497 19.50 ENST00000355857.3
ENST00000535617.1
ENST00000535757.1
ENST00000409094.1
ENST00000311521.4
DBI
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr12_-_57082060 19.45 ENST00000448157.2
ENST00000414274.3
ENST00000262033.6
ENST00000456859.2
PTGES3
prostaglandin E synthase 3 (cytosolic)
chr8_-_101734170 19.42 ENST00000522387.1
ENST00000518196.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr11_-_64085533 19.40 ENST00000544844.1
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr5_-_112257914 19.35 ENST00000513339.1
ENST00000545426.1
ENST00000504247.1
REEP5
receptor accessory protein 5
chr4_+_57843876 19.27 ENST00000450656.1
ENST00000381227.1
POLR2B
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of CXXC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
27.9 83.8 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
26.4 79.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
21.9 87.7 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
19.4 155.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
18.9 94.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
18.7 56.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
18.7 18.7 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
17.2 51.7 GO:0001922 B-1 B cell homeostasis(GO:0001922)
17.2 68.9 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
16.3 49.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
16.2 48.7 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
13.6 81.8 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
13.5 13.5 GO:0060623 regulation of chromosome condensation(GO:0060623)
12.1 48.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
11.5 34.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
11.1 33.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
10.6 42.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
10.0 69.7 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
9.6 28.9 GO:0046294 formaldehyde catabolic process(GO:0046294)
9.0 27.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
9.0 45.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
8.8 35.3 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
8.6 25.7 GO:2001162 regulation of genetic imprinting(GO:2000653) regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
8.5 25.6 GO:1901873 regulation of post-translational protein modification(GO:1901873)
8.3 24.9 GO:1902822 cleavage furrow ingression(GO:0036090) regulation of late endosome to lysosome transport(GO:1902822)
8.1 24.4 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
7.9 79.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
7.7 23.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
7.7 15.4 GO:0046075 dTTP metabolic process(GO:0046075)
7.7 38.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
7.7 15.3 GO:0007113 endomitotic cell cycle(GO:0007113)
7.6 45.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
7.6 52.9 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
7.5 15.0 GO:0046292 formaldehyde metabolic process(GO:0046292)
7.4 22.1 GO:0006097 glyoxylate cycle(GO:0006097)
7.1 28.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
6.9 97.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
6.9 34.6 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
6.8 27.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
6.7 20.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
6.6 32.9 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
6.3 19.0 GO:0032790 ribosome disassembly(GO:0032790)
6.3 31.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
6.3 18.9 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
6.2 62.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
6.2 37.3 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
6.2 18.5 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
6.1 18.4 GO:0015680 intracellular copper ion transport(GO:0015680)
6.1 18.4 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
6.1 42.6 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
6.0 30.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
5.9 5.9 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
5.8 23.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
5.7 34.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
5.7 34.0 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
5.6 22.4 GO:0072683 T cell extravasation(GO:0072683)
5.6 16.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
5.5 16.6 GO:0070602 negative regulation of mitotic cell cycle, embryonic(GO:0045976) regulation of centromeric sister chromatid cohesion(GO:0070602) renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) positive regulation of determination of dorsal identity(GO:2000017)
5.5 21.9 GO:0032218 riboflavin transport(GO:0032218)
5.5 16.4 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
5.4 27.0 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
5.4 102.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
5.3 21.4 GO:0043335 protein unfolding(GO:0043335)
5.1 20.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
5.0 49.8 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
4.9 24.7 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
4.8 19.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
4.8 23.8 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
4.8 4.8 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
4.7 9.5 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
4.7 14.1 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
4.6 23.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
4.6 27.6 GO:0006021 inositol biosynthetic process(GO:0006021)
4.6 36.8 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
4.6 18.2 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
4.5 13.4 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
4.4 17.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
4.4 43.5 GO:0071763 nuclear membrane organization(GO:0071763)
4.3 12.9 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
4.3 80.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
4.2 17.0 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
4.2 24.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
4.1 29.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
4.1 66.1 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
4.1 20.5 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
4.1 12.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
4.0 44.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
4.0 16.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
3.9 11.8 GO:0042256 mature ribosome assembly(GO:0042256)
3.9 137.6 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
3.9 23.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
3.9 42.4 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
3.8 19.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
3.7 18.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
3.7 7.4 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
3.7 11.0 GO:0061198 fungiform papilla formation(GO:0061198)
3.6 10.9 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
3.6 10.8 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
3.5 17.6 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
3.5 14.0 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
3.5 13.9 GO:1903976 negative regulation of glial cell migration(GO:1903976)
3.5 13.9 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
3.5 52.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
3.4 20.5 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
3.4 34.1 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
3.4 40.9 GO:0018206 peptidyl-methionine modification(GO:0018206)
3.4 10.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
3.3 13.4 GO:0030242 pexophagy(GO:0030242)
3.3 49.8 GO:0033523 histone H2B ubiquitination(GO:0033523)
3.3 46.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
3.3 79.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
3.3 9.9 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
3.3 13.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
3.3 78.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
3.2 44.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
3.1 12.5 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
3.1 31.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
3.1 31.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
3.1 12.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
3.1 220.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
3.0 9.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
3.0 15.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
3.0 6.0 GO:0046060 dATP metabolic process(GO:0046060)
3.0 24.0 GO:0002934 desmosome organization(GO:0002934)
2.9 8.8 GO:0048250 mitochondrial iron ion transport(GO:0048250)
2.9 11.6 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
2.9 29.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
2.8 11.2 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
2.8 19.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
2.8 16.7 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
2.7 5.5 GO:0034201 response to oleic acid(GO:0034201)
2.7 46.5 GO:0007220 Notch receptor processing(GO:0007220)
2.7 13.6 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.7 8.1 GO:0048627 myoblast development(GO:0048627)
2.7 10.7 GO:0046086 adenosine biosynthetic process(GO:0046086)
2.6 15.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
2.6 13.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
2.6 10.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
2.5 20.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
2.5 25.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
2.5 20.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.5 7.4 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
2.5 14.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
2.5 9.9 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.5 9.8 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.5 12.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
2.4 9.8 GO:0071492 cellular response to UV-A(GO:0071492)
2.4 12.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
2.4 14.6 GO:0001675 acrosome assembly(GO:0001675)
2.4 9.7 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
2.4 16.8 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
2.4 16.8 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
2.4 11.8 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
2.4 7.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
2.3 7.0 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
2.3 32.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
2.3 38.6 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
2.3 9.1 GO:0048254 snoRNA localization(GO:0048254)
2.3 6.8 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
2.3 60.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
2.2 17.7 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
2.2 19.9 GO:0033327 Leydig cell differentiation(GO:0033327)
2.2 6.6 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
2.2 8.7 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
2.1 8.6 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
2.1 2.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
2.1 17.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
2.1 12.7 GO:0010643 cell communication by chemical coupling(GO:0010643)
2.1 21.1 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
2.1 6.3 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.1 58.7 GO:0031639 plasminogen activation(GO:0031639)
2.1 16.7 GO:0032055 negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
2.1 85.6 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
2.1 12.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.0 20.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
2.0 24.5 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
2.0 22.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
2.0 41.9 GO:0008334 histone mRNA metabolic process(GO:0008334)
2.0 9.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
2.0 11.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.9 7.8 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
1.9 9.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.9 5.8 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
1.9 9.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.9 5.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.9 18.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
1.8 20.2 GO:0006621 protein retention in ER lumen(GO:0006621)
1.8 9.0 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
1.7 17.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
1.7 36.2 GO:0050872 white fat cell differentiation(GO:0050872)
1.7 27.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
1.7 30.8 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
1.7 70.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
1.7 5.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
1.7 8.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
1.7 10.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
1.7 217.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
1.7 5.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.7 14.9 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)
1.6 13.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.6 19.5 GO:0070365 hepatocyte differentiation(GO:0070365)
1.6 8.1 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
1.6 9.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
1.6 6.4 GO:2000354 regulation of ovarian follicle development(GO:2000354)
1.6 301.4 GO:0043488 regulation of mRNA stability(GO:0043488)
1.6 23.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
1.5 12.3 GO:0006013 mannose metabolic process(GO:0006013)
1.5 65.9 GO:0061462 protein localization to lysosome(GO:0061462)
1.5 23.0 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.5 10.7 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.5 28.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.5 27.1 GO:0044818 mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818)
1.5 15.0 GO:0015939 pantothenate metabolic process(GO:0015939)
1.5 7.5 GO:0031648 protein destabilization(GO:0031648)
1.5 41.5 GO:0043968 histone H2A acetylation(GO:0043968)
1.5 24.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
1.5 1.5 GO:0019249 lactate biosynthetic process(GO:0019249)
1.4 4.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.4 19.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
1.4 109.8 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
1.4 5.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
1.4 12.3 GO:1901838 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
1.4 8.1 GO:0006177 GMP biosynthetic process(GO:0006177)
1.3 1.3 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
1.3 60.3 GO:0043486 histone exchange(GO:0043486)
1.3 8.0 GO:0030421 defecation(GO:0030421)
1.3 39.8 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
1.3 11.9 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
1.3 10.5 GO:0015693 magnesium ion transport(GO:0015693)
1.3 3.9 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
1.3 3.9 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.3 16.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
1.2 5.0 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
1.2 13.6 GO:0018345 protein palmitoylation(GO:0018345)
1.2 17.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
1.2 7.3 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
1.2 9.6 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
1.2 29.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
1.2 5.9 GO:0016036 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
1.2 16.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
1.2 11.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
1.2 3.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.2 37.1 GO:0006301 postreplication repair(GO:0006301)
1.2 8.1 GO:1990592 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.2 4.6 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
1.2 6.9 GO:0090170 regulation of Golgi inheritance(GO:0090170)
1.1 12.6 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
1.1 17.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
1.1 84.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.1 11.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.1 5.6 GO:0006983 ER overload response(GO:0006983)
1.1 12.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
1.1 27.5 GO:0009235 cobalamin metabolic process(GO:0009235)
1.1 6.4 GO:0006540 glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
1.1 3.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.0 17.6 GO:0006379 mRNA cleavage(GO:0006379)
1.0 2.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
1.0 6.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.0 8.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.0 4.0 GO:0031268 pseudopodium organization(GO:0031268)
1.0 5.0 GO:0030047 actin modification(GO:0030047)
1.0 10.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.0 2.9 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
1.0 25.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.0 3.8 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.9 2.8 GO:0043317 regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318) insulin catabolic process(GO:1901143)
0.9 13.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.9 8.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.9 9.1 GO:0031053 primary miRNA processing(GO:0031053)
0.9 43.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.9 42.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.9 2.7 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.9 19.2 GO:1904667 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.9 51.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.9 1.7 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.8 3.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.8 2.5 GO:0051402 neuron apoptotic process(GO:0051402)
0.8 2.5 GO:0009303 rRNA transcription(GO:0009303)
0.8 10.8 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.8 6.6 GO:0007007 inner mitochondrial membrane organization(GO:0007007) cristae formation(GO:0042407)
0.8 17.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.8 4.8 GO:0032328 alanine transport(GO:0032328)
0.8 46.8 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.8 9.4 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.8 4.7 GO:0036258 multivesicular body assembly(GO:0036258)
0.8 3.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.8 2.3 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.8 5.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.7 5.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.7 5.9 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.7 17.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.7 30.6 GO:0045727 positive regulation of translation(GO:0045727)
0.7 5.7 GO:0051601 exocyst localization(GO:0051601)
0.7 6.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.7 5.6 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.7 7.6 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.7 3.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.7 10.2 GO:0000338 protein deneddylation(GO:0000338)
0.7 4.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.7 96.9 GO:0000910 cytokinesis(GO:0000910)
0.7 126.6 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.7 11.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.7 3.9 GO:0055064 chloride ion homeostasis(GO:0055064)
0.6 6.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.6 26.5 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.6 30.3 GO:0032272 negative regulation of protein polymerization(GO:0032272)
0.6 2.5 GO:0032489 aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) platelet dense granule organization(GO:0060155) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.6 32.5 GO:0042348 regulation of NF-kappaB import into nucleus(GO:0042345) NF-kappaB import into nucleus(GO:0042348)
0.6 25.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.6 4.3 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.6 3.0 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.6 26.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.6 10.1 GO:0000732 strand displacement(GO:0000732)
0.6 6.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.6 1.8 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.6 1.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.6 6.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.6 12.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.6 16.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.6 10.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.6 5.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.6 21.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.6 2.8 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.6 1.7 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.6 5.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 2.7 GO:0021759 globus pallidus development(GO:0021759)
0.5 8.1 GO:0016579 protein deubiquitination(GO:0016579)
0.5 7.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.5 26.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.5 6.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.5 3.6 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.5 29.4 GO:0006413 translational initiation(GO:0006413)
0.5 52.4 GO:0006338 chromatin remodeling(GO:0006338)
0.5 4.9 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.5 1.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.5 12.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.5 3.3 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.5 35.8 GO:0008033 tRNA processing(GO:0008033)
0.5 2.3 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.5 12.2 GO:2001222 regulation of neuron migration(GO:2001222)
0.5 15.8 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.4 5.4 GO:0048311 mitochondrion distribution(GO:0048311)
0.4 6.6 GO:0051639 actin filament network formation(GO:0051639)
0.4 12.5 GO:0006270 DNA replication initiation(GO:0006270)
0.4 2.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 5.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.4 3.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.4 4.6 GO:0061684 chaperone-mediated autophagy(GO:0061684)
0.4 3.3 GO:0016180 snRNA processing(GO:0016180)
0.4 8.5 GO:0044804 nucleophagy(GO:0044804)
0.4 16.8 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.4 2.6 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.4 14.0 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 10.8 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.4 8.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.4 2.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.3 2.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 3.8 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.3 3.1 GO:0045109 intermediate filament organization(GO:0045109)
0.3 8.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.3 2.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 1.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.3 3.6 GO:0006183 GTP biosynthetic process(GO:0006183)
0.3 2.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.3 1.9 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.3 26.2 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3 18.9 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.3 18.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.3 10.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.3 1.2 GO:0031054 pre-miRNA processing(GO:0031054)
0.3 8.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 2.0 GO:0070828 heterochromatin organization(GO:0070828)
0.3 2.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 17.7 GO:0006401 RNA catabolic process(GO:0006401)
0.3 3.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.3 5.3 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.3 17.6 GO:0051225 spindle assembly(GO:0051225)
0.3 9.1 GO:0010761 fibroblast migration(GO:0010761)
0.3 4.7 GO:0032508 DNA duplex unwinding(GO:0032508)
0.3 3.8 GO:0030042 actin filament depolymerization(GO:0030042)
0.2 1.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 17.1 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.2 3.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 3.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 4.7 GO:0035455 response to interferon-alpha(GO:0035455)
0.2 0.6 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 2.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 5.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.2 2.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2 3.5 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.2 13.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 1.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2 8.5 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 2.0 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.2 3.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 0.7 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.2 22.5 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.2 6.5 GO:0007565 female pregnancy(GO:0007565)
0.1 26.5 GO:0006260 DNA replication(GO:0006260)
0.1 1.2 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 4.8 GO:0006342 chromatin silencing(GO:0006342)
0.1 1.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 8.6 GO:1904064 positive regulation of cation transmembrane transport(GO:1904064)
0.1 4.5 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 4.7 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 12.2 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.1 2.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 10.3 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 1.4 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 6.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 2.0 GO:0030728 ovulation(GO:0030728)
0.1 2.0 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 7.9 GO:0007030 Golgi organization(GO:0007030)
0.1 0.7 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.1 0.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 1.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 3.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 6.0 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 5.9 GO:0002576 platelet degranulation(GO:0002576)
0.1 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:1903943 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 5.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.1 GO:0070673 response to interleukin-18(GO:0070673)
0.0 1.0 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.8 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.2 GO:0055098 response to lipoprotein particle(GO:0055094) response to low-density lipoprotein particle(GO:0055098) cellular response to lipoprotein particle stimulus(GO:0071402) cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0 2.7 GO:0031424 keratinization(GO:0031424)
0.0 1.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.9 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.5 GO:0002062 chondrocyte differentiation(GO:0002062)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
17.1 51.4 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
16.8 83.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
12.6 37.9 GO:0031262 Ndc80 complex(GO:0031262)
12.4 49.5 GO:0070985 TFIIK complex(GO:0070985)
11.5 92.1 GO:0032133 chromosome passenger complex(GO:0032133)
10.6 42.4 GO:0044611 nuclear pore inner ring(GO:0044611)
9.4 18.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
9.1 36.6 GO:0001405 presequence translocase-associated import motor(GO:0001405)
8.6 77.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
8.4 25.2 GO:0034455 t-UTP complex(GO:0034455)
8.3 25.0 GO:0031523 Myb complex(GO:0031523)
7.7 38.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
7.4 200.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
7.3 36.7 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
6.9 89.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
6.7 74.0 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
6.7 13.4 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
6.6 79.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
6.5 39.0 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
6.4 25.7 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
6.1 30.4 GO:0005726 perichromatin fibrils(GO:0005726)
5.9 23.8 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
5.8 46.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
5.5 32.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
5.3 58.3 GO:0070765 gamma-secretase complex(GO:0070765)
5.2 26.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
5.2 41.9 GO:0005683 U7 snRNP(GO:0005683)
5.1 20.4 GO:0031417 NatC complex(GO:0031417)
5.1 20.3 GO:0000811 GINS complex(GO:0000811)
4.9 73.7 GO:0031080 nuclear pore outer ring(GO:0031080)
4.8 58.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
4.7 70.5 GO:0044754 autolysosome(GO:0044754)
4.7 46.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
4.5 27.3 GO:0070545 PeBoW complex(GO:0070545)
4.2 50.9 GO:0030008 TRAPP complex(GO:0030008)
4.2 29.2 GO:0071203 WASH complex(GO:0071203)
4.0 27.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
3.9 19.5 GO:0016589 NURF complex(GO:0016589)
3.9 54.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
3.9 15.5 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
3.9 38.6 GO:0070938 contractile ring(GO:0070938)
3.8 73.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
3.7 56.2 GO:0045277 respiratory chain complex IV(GO:0045277)
3.7 89.6 GO:0016580 Sin3 complex(GO:0016580)
3.6 10.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
3.5 146.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
3.3 16.6 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
3.2 32.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
3.2 16.1 GO:0033503 HULC complex(GO:0033503)
3.2 9.6 GO:0070195 growth hormone receptor complex(GO:0070195)
3.2 25.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
3.2 9.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
3.1 24.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
3.0 3.0 GO:0048500 signal recognition particle(GO:0048500)
2.9 20.2 GO:0005955 calcineurin complex(GO:0005955)
2.8 19.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
2.8 83.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
2.7 13.6 GO:0089701 U2AF(GO:0089701)
2.7 18.9 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
2.6 44.7 GO:0005686 U2 snRNP(GO:0005686)
2.6 186.3 GO:0005637 nuclear inner membrane(GO:0005637)
2.6 13.0 GO:0097422 tubular endosome(GO:0097422)
2.6 61.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
2.5 40.8 GO:0030014 CCR4-NOT complex(GO:0030014)
2.5 35.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
2.4 14.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
2.4 7.2 GO:0035189 Rb-E2F complex(GO:0035189)
2.4 16.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
2.4 9.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
2.4 14.1 GO:0071817 MMXD complex(GO:0071817)
2.3 37.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
2.3 20.7 GO:0000125 PCAF complex(GO:0000125)
2.3 9.1 GO:0005687 U4 snRNP(GO:0005687)
2.2 13.5 GO:0001740 Barr body(GO:0001740)
2.2 20.1 GO:0000796 condensin complex(GO:0000796)
2.1 17.2 GO:0034719 SMN-Sm protein complex(GO:0034719)
2.1 12.7 GO:0070470 plasma membrane respiratory chain(GO:0070470)
2.1 12.6 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
2.1 14.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
2.1 23.0 GO:0030123 AP-3 adaptor complex(GO:0030123)
2.0 6.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
2.0 34.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
2.0 14.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
2.0 10.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
2.0 35.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
2.0 31.2 GO:0032433 filopodium tip(GO:0032433)
1.9 17.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
1.9 43.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.9 26.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
1.8 14.7 GO:0042382 paraspeckles(GO:0042382)
1.8 3.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
1.8 8.9 GO:0071986 Ragulator complex(GO:0071986)
1.8 28.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
1.8 3.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.7 87.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.7 16.9 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
1.7 36.9 GO:0002080 acrosomal membrane(GO:0002080)
1.7 31.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
1.7 3.3 GO:0071159 NF-kappaB complex(GO:0071159)
1.6 4.9 GO:0005674 transcription factor TFIIF complex(GO:0005674)
1.6 11.3 GO:0016272 prefoldin complex(GO:0016272)
1.6 31.2 GO:0030137 COPI-coated vesicle(GO:0030137)
1.6 4.7 GO:0033565 ESCRT-0 complex(GO:0033565)
1.6 23.3 GO:0005662 DNA replication factor A complex(GO:0005662)
1.5 10.8 GO:0044194 cytolytic granule(GO:0044194)
1.5 16.7 GO:0005641 nuclear envelope lumen(GO:0005641)
1.5 28.8 GO:0030686 90S preribosome(GO:0030686)
1.5 19.2 GO:0008385 IkappaB kinase complex(GO:0008385)
1.5 11.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.4 8.6 GO:0097452 GAIT complex(GO:0097452)
1.4 146.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.4 5.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.4 18.3 GO:0005838 proteasome regulatory particle(GO:0005838)
1.4 25.1 GO:0097342 ripoptosome(GO:0097342)
1.4 9.7 GO:0002178 palmitoyltransferase complex(GO:0002178)
1.4 9.7 GO:0030870 Mre11 complex(GO:0030870)
1.4 5.5 GO:0042788 polysomal ribosome(GO:0042788)
1.4 26.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.4 8.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.4 35.5 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
1.4 12.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.3 105.0 GO:0070469 respiratory chain(GO:0070469)
1.3 18.7 GO:0097227 sperm annulus(GO:0097227)
1.3 13.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
1.3 17.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.3 16.6 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
1.3 7.6 GO:0005828 kinetochore microtubule(GO:0005828)
1.3 21.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.3 37.9 GO:0030057 desmosome(GO:0030057)
1.3 5.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.2 7.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.2 83.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.2 79.9 GO:0015935 small ribosomal subunit(GO:0015935)
1.2 21.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.1 14.9 GO:0000815 ESCRT III complex(GO:0000815)
1.1 8.9 GO:0042575 DNA polymerase complex(GO:0042575)
1.1 10.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.1 3.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
1.0 7.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
1.0 179.4 GO:0005681 spliceosomal complex(GO:0005681)
1.0 97.9 GO:0035578 azurophil granule lumen(GO:0035578)
1.0 39.7 GO:0000502 proteasome complex(GO:0000502)
1.0 48.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
1.0 10.1 GO:0042555 MCM complex(GO:0042555)
1.0 13.0 GO:0097470 ribbon synapse(GO:0097470)
1.0 12.7 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
1.0 4.9 GO:0005899 insulin receptor complex(GO:0005899)
1.0 90.7 GO:0005643 nuclear pore(GO:0005643)
0.9 6.6 GO:0000813 ESCRT I complex(GO:0000813)
0.9 6.5 GO:0045171 intercellular bridge(GO:0045171)
0.9 35.7 GO:0044391 ribosomal subunit(GO:0044391)
0.8 22.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.8 4.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.8 5.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.8 17.9 GO:0031143 pseudopodium(GO:0031143)
0.8 7.2 GO:0070652 HAUS complex(GO:0070652)
0.8 27.3 GO:0005876 spindle microtubule(GO:0005876)
0.8 19.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.8 33.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.8 17.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.7 85.0 GO:0016605 PML body(GO:0016605)
0.7 8.1 GO:0097443 sorting endosome(GO:0097443)
0.7 36.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.7 12.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.7 8.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.7 8.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.7 14.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.6 5.6 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.6 4.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.6 6.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.5 5.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.5 30.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.5 5.0 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.5 24.5 GO:0001772 immunological synapse(GO:0001772)
0.5 5.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.5 33.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.5 41.0 GO:1902493 protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
0.4 6.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.4 17.3 GO:0031430 M band(GO:0031430)
0.4 4.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 7.9 GO:0042599 lamellar body(GO:0042599)
0.4 5.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 3.3 GO:0032039 integrator complex(GO:0032039)
0.4 20.2 GO:0005801 cis-Golgi network(GO:0005801)
0.4 6.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.4 299.8 GO:0005730 nucleolus(GO:0005730)
0.4 48.3 GO:0030496 midbody(GO:0030496)
0.3 20.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 9.8 GO:1904115 axon cytoplasm(GO:1904115)
0.3 17.1 GO:0005667 transcription factor complex(GO:0005667)
0.3 5.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 10.2 GO:0008180 COP9 signalosome(GO:0008180)
0.3 2.0 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.3 5.8 GO:0005771 multivesicular body(GO:0005771)
0.3 15.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.3 1.9 GO:0005610 laminin-5 complex(GO:0005610)
0.3 2.1 GO:0005844 polysome(GO:0005844)
0.3 3.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 6.2 GO:0035580 specific granule lumen(GO:0035580)
0.3 26.7 GO:0035579 specific granule membrane(GO:0035579)
0.2 4.5 GO:0031527 filopodium membrane(GO:0031527)
0.2 1.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 1.9 GO:0042581 specific granule(GO:0042581)
0.2 62.4 GO:0005635 nuclear envelope(GO:0005635)
0.2 19.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 5.9 GO:0005921 gap junction(GO:0005921)
0.2 1.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.2 48.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.2 3.8 GO:0005581 collagen trimer(GO:0005581)
0.2 4.5 GO:0031904 endosome lumen(GO:0031904)
0.1 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 5.4 GO:0002102 podosome(GO:0002102)
0.1 2.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 33.0 GO:0019866 organelle inner membrane(GO:0019866)
0.1 2.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 4.7 GO:0005884 actin filament(GO:0005884)
0.1 10.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 4.0 GO:0045095 keratin filament(GO:0045095)
0.1 3.4 GO:0005811 lipid particle(GO:0005811)
0.1 12.1 GO:0032993 protein-DNA complex(GO:0032993)
0.1 2.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 4.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.5 GO:0016324 apical plasma membrane(GO:0016324)
0.1 9.4 GO:0030018 Z disc(GO:0030018)
0.1 5.1 GO:0030175 filopodium(GO:0030175)
0.1 19.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 4.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 2.5 GO:0030017 sarcomere(GO:0030017)
0.0 3.1 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.0 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
29.2 87.7 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
19.5 58.6 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
17.3 51.9 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
16.7 133.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
16.5 49.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
15.9 47.6 GO:0017130 poly(C) RNA binding(GO:0017130)
12.8 140.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
12.6 37.9 GO:0050613 delta14-sterol reductase activity(GO:0050613)
12.5 37.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
12.5 49.8 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
12.0 83.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
10.8 43.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
9.9 89.5 GO:0035174 histone serine kinase activity(GO:0035174)
9.8 68.9 GO:0004849 uridine kinase activity(GO:0004849)
8.9 26.6 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
8.8 26.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
8.2 49.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
7.4 22.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
7.3 29.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
7.2 28.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
6.9 27.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
6.8 27.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
6.5 39.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
6.4 32.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
6.3 81.7 GO:0008641 small protein activating enzyme activity(GO:0008641)
6.1 24.5 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
6.1 18.3 GO:0004771 sterol esterase activity(GO:0004771)
6.0 54.4 GO:1990226 histone methyltransferase binding(GO:1990226)
5.8 17.5 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
5.8 28.9 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
5.5 27.6 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
5.5 21.9 GO:0032217 riboflavin transporter activity(GO:0032217)
5.5 16.4 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
5.4 76.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
5.4 27.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
5.4 27.0 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
5.3 63.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
5.0 20.2 GO:0005046 KDEL sequence binding(GO:0005046)
5.0 44.6 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
4.7 61.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
4.7 28.2 GO:0016531 copper chaperone activity(GO:0016531)
4.7 23.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
4.6 13.9 GO:0010698 acetyltransferase activator activity(GO:0010698)
4.6 18.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
4.6 77.4 GO:0003688 DNA replication origin binding(GO:0003688)
4.5 13.4 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
4.4 8.7 GO:0003998 acylphosphatase activity(GO:0003998)
4.3 52.1 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
4.2 16.7 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
4.1 36.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
4.0 16.2 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
4.0 12.0 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
3.9 31.4 GO:0016842 amidine-lyase activity(GO:0016842)
3.9 116.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
3.8 23.1 GO:0042296 ISG15 transferase activity(GO:0042296)
3.8 22.8 GO:0019238 cyclohydrolase activity(GO:0019238)
3.7 37.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
3.7 14.6 GO:0043515 kinetochore binding(GO:0043515)
3.6 18.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
3.5 14.1 GO:0016748 succinyltransferase activity(GO:0016748)
3.5 102.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
3.5 31.5 GO:0015288 porin activity(GO:0015288)
3.5 100.3 GO:0070410 co-SMAD binding(GO:0070410)
3.4 13.6 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
3.4 37.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
3.3 10.0 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
3.3 23.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
3.3 9.9 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
3.3 26.3 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
3.3 22.8 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
3.2 9.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
3.2 134.5 GO:0031369 translation initiation factor binding(GO:0031369)
3.2 9.6 GO:0005148 prolactin receptor binding(GO:0005148)
3.2 57.0 GO:0008266 poly(U) RNA binding(GO:0008266)
3.1 12.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
3.1 15.4 GO:0032552 deoxyribonucleotide binding(GO:0032552)
3.1 21.4 GO:0030911 TPR domain binding(GO:0030911)
3.0 30.0 GO:0019237 centromeric DNA binding(GO:0019237)
3.0 14.8 GO:0008494 translation activator activity(GO:0008494)
2.9 61.3 GO:0001055 RNA polymerase II activity(GO:0001055)
2.9 52.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
2.9 74.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.8 16.9 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
2.8 11.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
2.8 14.0 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
2.8 28.0 GO:0042301 phosphate ion binding(GO:0042301)
2.8 5.6 GO:0044388 small protein activating enzyme binding(GO:0044388)
2.7 13.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
2.7 24.4 GO:0008312 7S RNA binding(GO:0008312)
2.6 41.4 GO:0004526 ribonuclease P activity(GO:0004526)
2.5 15.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
2.5 5.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
2.5 22.4 GO:0035877 death effector domain binding(GO:0035877)
2.5 217.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
2.5 41.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.4 19.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
2.4 29.3 GO:0031386 protein tag(GO:0031386)
2.4 48.4 GO:0070717 poly-purine tract binding(GO:0070717)
2.4 14.5 GO:0019776 Atg8 ligase activity(GO:0019776)
2.4 7.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
2.3 13.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
2.3 27.8 GO:0017070 U6 snRNA binding(GO:0017070)
2.3 6.8 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
2.3 56.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
2.2 10.8 GO:0030348 syntaxin-3 binding(GO:0030348)
2.1 23.6 GO:0070182 DNA polymerase binding(GO:0070182)
2.1 30.0 GO:0016018 cyclosporin A binding(GO:0016018)
2.1 89.8 GO:0000049 tRNA binding(GO:0000049)
2.1 8.4 GO:0038025 reelin receptor activity(GO:0038025)
2.1 10.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
2.1 47.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
2.0 6.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
2.0 8.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
2.0 60.7 GO:0070064 proline-rich region binding(GO:0070064)
2.0 36.4 GO:0031404 chloride ion binding(GO:0031404)
2.0 9.9 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
2.0 5.9 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
2.0 51.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.9 19.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.9 31.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.9 13.6 GO:0035613 RNA stem-loop binding(GO:0035613)
1.9 52.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.9 33.6 GO:0000339 RNA cap binding(GO:0000339)
1.8 20.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
1.8 11.0 GO:0097322 7SK snRNA binding(GO:0097322)
1.8 7.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
1.8 9.1 GO:0030621 U4 snRNA binding(GO:0030621)
1.8 12.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.8 121.6 GO:0050681 androgen receptor binding(GO:0050681)
1.8 16.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.7 12.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
1.7 5.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.6 6.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
1.6 14.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
1.6 9.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
1.6 14.3 GO:0030620 U2 snRNA binding(GO:0030620)
1.6 23.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.5 46.4 GO:0070063 RNA polymerase binding(GO:0070063)
1.5 4.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.5 31.6 GO:0003924 GTPase activity(GO:0003924)
1.4 12.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
1.4 11.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.3 89.5 GO:0008235 metalloexopeptidase activity(GO:0008235)
1.3 5.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
1.3 17.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.3 20.5 GO:0017049 GTP-Rho binding(GO:0017049)
1.2 19.8 GO:0070034 telomerase RNA binding(GO:0070034)
1.2 9.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.2 13.4 GO:0003713 transcription coactivator activity(GO:0003713)
1.2 21.0 GO:0035497 cAMP response element binding(GO:0035497)
1.2 46.6 GO:0003743 translation initiation factor activity(GO:0003743)
1.2 31.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.2 23.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.1 17.9 GO:0016004 phospholipase activator activity(GO:0016004)
1.1 121.1 GO:0003697 single-stranded DNA binding(GO:0003697)
1.1 6.6 GO:0004527 exonuclease activity(GO:0004527)
1.1 12.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
1.1 6.5 GO:0042610 CD8 receptor binding(GO:0042610)
1.1 8.7 GO:0016778 diphosphotransferase activity(GO:0016778)
1.1 13.0 GO:0034452 dynactin binding(GO:0034452)
1.1 56.9 GO:0019843 rRNA binding(GO:0019843)
1.1 6.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
1.0 12.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.0 6.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
1.0 50.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.0 2.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.0 10.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.0 11.6 GO:1990459 transferrin receptor binding(GO:1990459)
1.0 3.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.9 4.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.9 7.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.9 8.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.9 19.0 GO:0005123 death receptor binding(GO:0005123)
0.9 8.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.9 15.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.9 4.5 GO:0050436 microfibril binding(GO:0050436)
0.9 43.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.9 34.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.9 30.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.9 9.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.9 3.5 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.9 2.6 GO:0015235 cobalamin transporter activity(GO:0015235)
0.9 20.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.8 5.9 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.8 2.5 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.8 9.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.8 28.5 GO:0001671 ATPase activator activity(GO:0001671)
0.8 19.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.8 18.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.8 3.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.8 23.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 10.2 GO:0030515 snoRNA binding(GO:0030515)
0.7 12.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.7 12.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.7 86.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.7 30.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.7 3.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.7 2.8 GO:0004966 galanin receptor activity(GO:0004966)
0.7 2.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.7 13.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.7 107.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.7 9.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.7 17.7 GO:0070840 dynein complex binding(GO:0070840)
0.7 35.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6 24.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.6 9.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 2.6 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.6 25.8 GO:0050699 WW domain binding(GO:0050699)
0.6 5.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.6 2.6 GO:0017040 ceramidase activity(GO:0017040)
0.6 8.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.6 15.7 GO:0031489 myosin V binding(GO:0031489)
0.6 10.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.6 6.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.6 6.7 GO:0019211 phosphatase activator activity(GO:0019211)
0.6 18.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.6 46.9 GO:0032947 protein complex scaffold(GO:0032947)
0.6 18.6 GO:0043236 laminin binding(GO:0043236)
0.6 16.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6 1.8 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.6 8.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.6 4.7 GO:0005536 glucose binding(GO:0005536)
0.6 5.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.6 3.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 14.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.6 9.7 GO:0005522 profilin binding(GO:0005522)
0.5 1.6 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.5 5.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.5 661.4 GO:0003723 RNA binding(GO:0003723)
0.5 5.3 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5 6.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.5 2.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.5 11.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 3.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5 11.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 1.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 1.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.5 5.0 GO:0031491 nucleosome binding(GO:0031491)
0.5 68.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 1.7 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.4 34.2 GO:0043130 ubiquitin binding(GO:0043130)
0.4 2.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 4.3 GO:0016421 CoA carboxylase activity(GO:0016421)
0.4 49.5 GO:0042393 histone binding(GO:0042393)
0.4 22.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 1.4 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.4 2.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.3 1.0 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 2.3 GO:0032183 SUMO binding(GO:0032183)
0.3 4.5 GO:0009881 photoreceptor activity(GO:0009881)
0.3 2.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 5.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 6.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 2.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 11.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 3.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 4.6 GO:0004697 protein kinase C activity(GO:0004697)
0.3 4.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 8.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 3.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 4.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 3.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 7.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 7.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 2.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 3.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 0.7 GO:0070728 leucine binding(GO:0070728)
0.2 4.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 1.5 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.2 3.8 GO:0005537 mannose binding(GO:0005537)
0.2 2.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2 0.7 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 2.8 GO:0005112 Notch binding(GO:0005112)
0.2 0.6 GO:1903135 cupric ion binding(GO:1903135)
0.2 3.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.2 0.6 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 2.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 5.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 45.4 GO:0005525 GTP binding(GO:0005525)
0.1 2.6 GO:0019239 deaminase activity(GO:0019239)
0.1 2.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 2.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 12.3 GO:0008237 metallopeptidase activity(GO:0008237)
0.1 3.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 1.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 2.3 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.8 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 1.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 9.5 GO:0019901 protein kinase binding(GO:0019901)
0.0 2.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0004180 carboxypeptidase activity(GO:0004180)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 224.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
2.4 277.8 PID AR PATHWAY Coregulation of Androgen receptor activity
1.8 111.9 PID ATR PATHWAY ATR signaling pathway
1.8 32.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.8 91.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.5 49.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
1.3 49.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
1.3 56.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
1.2 89.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
1.2 27.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.1 42.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
1.0 49.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
1.0 56.1 PID AURORA B PATHWAY Aurora B signaling
1.0 54.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
1.0 17.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.9 34.4 PID PLK1 PATHWAY PLK1 signaling events
0.8 24.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.8 32.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.8 34.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.8 52.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.7 29.0 PID INSULIN PATHWAY Insulin Pathway
0.7 12.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.7 23.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.7 37.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.7 17.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.6 60.1 PID P73PATHWAY p73 transcription factor network
0.6 41.9 PID CDC42 PATHWAY CDC42 signaling events
0.6 35.8 PID E2F PATHWAY E2F transcription factor network
0.6 15.3 PID MYC PATHWAY C-MYC pathway
0.6 75.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.6 11.0 PID ALK2 PATHWAY ALK2 signaling events
0.6 16.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.5 34.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.4 4.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.4 4.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 21.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.4 15.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.4 18.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.4 10.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.4 26.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.4 15.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.4 17.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.3 3.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.3 11.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.3 8.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 7.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.3 8.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.3 8.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 20.7 PID CMYB PATHWAY C-MYB transcription factor network
0.3 4.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 3.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 2.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 9.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 3.5 PID IFNG PATHWAY IFN-gamma pathway
0.2 4.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.2 6.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 8.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 4.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 3.0 PID FOXO PATHWAY FoxO family signaling
0.1 5.0 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 99.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
6.1 92.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
5.0 84.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
4.1 74.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
4.1 61.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
4.1 36.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
3.5 283.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
3.5 58.7 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
3.2 93.7 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
3.2 22.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
3.1 31.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
3.1 178.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
2.9 250.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
2.9 28.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
2.9 111.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
2.8 39.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
2.8 98.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
2.7 118.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
2.7 83.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
2.6 47.2 REACTOME MRNA CAPPING Genes involved in mRNA Capping
2.5 5.0 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
2.5 49.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
2.4 7.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
2.3 42.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
2.3 83.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
2.3 48.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
2.3 79.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
2.2 15.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
2.0 24.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
2.0 31.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
1.9 44.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.9 116.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.9 16.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.9 54.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.8 134.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.7 171.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
1.7 44.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.5 26.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
1.5 23.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.5 50.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
1.4 227.6 REACTOME TRANSLATION Genes involved in Translation
1.4 37.6 REACTOME KINESINS Genes involved in Kinesins
1.4 18.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
1.4 22.5 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
1.4 29.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.4 23.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.4 19.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.3 13.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
1.3 17.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.3 59.0 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
1.3 55.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.3 11.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.2 40.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.2 28.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.2 19.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
1.2 31.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
1.1 43.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.1 29.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.1 3.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
1.1 17.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
1.1 8.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
1.0 63.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
1.0 34.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.9 31.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.9 15.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.8 43.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.8 22.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.8 4.9 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.8 5.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.8 8.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.8 40.7 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.7 17.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.7 12.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.7 13.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.6 8.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.6 14.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.6 94.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.6 13.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.6 15.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.6 20.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.5 23.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.5 21.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.5 8.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5 11.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 33.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.5 20.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.5 26.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.5 53.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.5 6.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 60.0 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.5 5.0 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.4 24.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 11.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.4 5.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.4 18.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.4 2.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.4 12.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.4 11.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.4 6.5 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.4 23.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 9.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.3 6.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 5.6 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.3 4.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 3.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 9.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 3.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 2.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 7.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 5.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 5.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 14.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 9.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 7.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 6.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 4.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 5.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME DNA REPAIR Genes involved in DNA Repair