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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for DBP

Z-value: 0.11

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Transcription factors associated with DBP

Gene Symbol Gene ID Gene Info
DBP
ENSG00000105516.6 D-box binding PAR bZIP transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DBPhg19_v2_chr19_-_49140609_491406430.194.8e-03Click!

Activity profile of DBP motif

Sorted Z-values of DBP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_57037284 14.42 ENST00000551570.1
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr4_-_176733897 11.11 ENST00000393658.2
GPM6A
glycoprotein M6A
chr20_+_11898507 8.76 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr11_+_121461097 8.57 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr4_+_158142750 7.07 ENST00000505888.1
ENST00000449365.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr8_+_85618155 6.62 ENST00000523850.1
ENST00000521376.1
RALYL
RALY RNA binding protein-like
chr5_-_111091948 6.55 ENST00000447165.2
NREP
neuronal regeneration related protein
chr3_-_33700589 6.10 ENST00000461133.3
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr8_-_54755459 5.96 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr7_-_150946015 5.56 ENST00000262188.8
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr8_-_102803163 5.55 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr1_+_84609944 5.43 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_-_31514516 5.26 ENST00000303892.5
ENST00000483251.1
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr6_-_31514333 5.18 ENST00000376151.4
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr16_+_7382745 5.06 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_+_113970772 4.70 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr15_+_80733570 4.60 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chrX_-_10851762 4.54 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr18_-_21891460 4.40 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr11_-_122931881 4.40 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chr3_+_123813509 4.38 ENST00000460856.1
ENST00000240874.3
KALRN
kalirin, RhoGEF kinase
chrX_+_56590002 4.36 ENST00000338222.5
UBQLN2
ubiquilin 2
chr7_+_26331541 4.21 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr13_-_67802549 4.07 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr7_-_37026108 3.92 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr8_-_80993010 3.92 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr4_+_71587669 3.83 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr1_+_87797351 3.78 ENST00000370542.1
LMO4
LIM domain only 4
chr14_+_29234870 3.67 ENST00000382535.3
FOXG1
forkhead box G1
chr2_+_210517895 3.58 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr9_-_139371533 3.58 ENST00000290037.6
ENST00000431893.2
ENST00000371706.3
SEC16A
SEC16 homolog A (S. cerevisiae)
chr11_+_35684288 3.41 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr9_-_139372141 3.35 ENST00000313050.7
SEC16A
SEC16 homolog A (S. cerevisiae)
chr8_+_85095553 3.30 ENST00000521268.1
RALYL
RALY RNA binding protein-like
chr8_+_85095769 3.17 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr3_-_33700933 3.11 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr2_+_210444748 3.08 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr12_-_89746173 3.06 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr4_-_74088800 3.02 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr5_-_134735568 2.92 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr4_-_186732048 2.90 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr2_-_60780536 2.90 ENST00000538214.1
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr4_-_87281224 2.90 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr4_+_114214125 2.86 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr4_-_87281196 2.71 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr8_+_107738240 2.71 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr2_-_88427568 2.66 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr8_+_9953061 2.57 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr8_+_9953214 2.56 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chrX_+_23801280 2.52 ENST00000379251.3
ENST00000379253.3
ENST00000379254.1
ENST00000379270.4
SAT1
spermidine/spermine N1-acetyltransferase 1
chr8_-_120685608 2.45 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_-_60780702 2.42 ENST00000359629.5
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr11_-_31832581 2.40 ENST00000379111.2
PAX6
paired box 6
chr6_-_75953484 2.32 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr17_+_2240775 2.26 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chr3_+_35721106 2.21 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr20_-_14318248 2.16 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr1_-_143767881 2.09 ENST00000419275.1
PPIAL4G
peptidylprolyl isomerase A (cyclophilin A)-like 4G
chr2_+_210444142 2.05 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr6_+_21593972 2.01 ENST00000244745.1
ENST00000543472.1
SOX4
SRY (sex determining region Y)-box 4
chr4_-_57547454 2.00 ENST00000556376.2
HOPX
HOP homeobox
chr22_+_38201114 2.00 ENST00000340857.2
H1F0
H1 histone family, member 0
chr14_+_29236269 1.93 ENST00000313071.4
FOXG1
forkhead box G1
chr8_-_22550815 1.91 ENST00000317216.2
EGR3
early growth response 3
chr8_-_17533838 1.87 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr4_-_16900410 1.85 ENST00000304523.5
LDB2
LIM domain binding 2
chr6_+_30687978 1.82 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr17_+_7487146 1.82 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr6_-_56819385 1.80 ENST00000370754.5
ENST00000449297.2
DST
dystonin
chr4_-_16900242 1.80 ENST00000502640.1
ENST00000506732.1
LDB2
LIM domain binding 2
chr17_+_2240916 1.76 ENST00000574563.1
SGSM2
small G protein signaling modulator 2
chr2_-_190044480 1.74 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr4_-_16900184 1.71 ENST00000515064.1
LDB2
LIM domain binding 2
chr6_+_10528560 1.68 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr19_-_42806919 1.65 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr2_-_65357225 1.64 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A
RAB1A, member RAS oncogene family
chr4_-_16900217 1.61 ENST00000441778.2
LDB2
LIM domain binding 2
chr8_+_26247878 1.61 ENST00000518611.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr11_+_64009072 1.59 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr2_+_166326157 1.57 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr3_-_48471454 1.53 ENST00000296440.6
ENST00000448774.2
PLXNB1
plexin B1
chr5_+_161495038 1.50 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr1_+_229440129 1.50 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr20_+_60718785 1.48 ENST00000421564.1
ENST00000450482.1
ENST00000331758.3
SS18L1
synovial sarcoma translocation gene on chromosome 18-like 1
chr9_+_2158485 1.44 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_71588372 1.44 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr12_-_120765565 1.42 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr6_+_3118926 1.41 ENST00000380379.5
BPHL
biphenyl hydrolase-like (serine hydrolase)
chr19_-_48894104 1.41 ENST00000597017.1
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr18_+_32621324 1.37 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr3_+_190333097 1.37 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chr13_+_97874574 1.32 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr11_+_112832090 1.30 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr4_+_160188889 1.27 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr5_+_161494770 1.27 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr5_+_161494521 1.23 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_+_234602305 1.22 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr2_-_21266935 1.21 ENST00000233242.1
APOB
apolipoprotein B
chr17_+_72426891 1.19 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr9_+_2158443 1.19 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_+_42429493 1.17 ENST00000586242.1
GRN
granulin
chr3_-_185538849 1.16 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_154229547 1.15 ENST00000428595.1
UBAP2L
ubiquitin associated protein 2-like
chr17_+_48823975 1.14 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr1_+_155051305 1.14 ENST00000368408.3
EFNA3
ephrin-A3
chr3_+_109128837 1.11 ENST00000497996.1
RP11-702L6.4
RP11-702L6.4
chr15_+_58702742 1.07 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr8_+_104310661 1.06 ENST00000522566.1
FZD6
frizzled family receptor 6
chr3_-_145878954 1.06 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr1_+_206557366 1.00 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr17_+_4613918 0.98 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2
arrestin, beta 2
chr7_-_104909435 0.96 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr7_+_99613212 0.95 ENST00000426572.1
ENST00000535170.1
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr10_+_47894572 0.95 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr4_-_89978299 0.94 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A
family with sequence similarity 13, member A
chr5_+_179921344 0.89 ENST00000261951.4
CNOT6
CCR4-NOT transcription complex, subunit 6
chr19_+_6361440 0.84 ENST00000245816.4
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr11_+_112832202 0.82 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr17_+_79953310 0.81 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr12_-_56236734 0.80 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr20_+_36405665 0.78 ENST00000373469.1
CTNNBL1
catenin, beta like 1
chr1_+_27648709 0.78 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
TMEM222
transmembrane protein 222
chr20_+_361261 0.77 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chrX_+_129473916 0.74 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr17_+_4613776 0.71 ENST00000269260.2
ARRB2
arrestin, beta 2
chr17_+_48624450 0.69 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20
spermatogenesis associated 20
chr4_+_39699664 0.69 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
UBE2K
ubiquitin-conjugating enzyme E2K
chr15_+_78632666 0.68 ENST00000299529.6
CRABP1
cellular retinoic acid binding protein 1
chr3_+_155838337 0.67 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr11_-_62414070 0.67 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr1_+_154540246 0.66 ENST00000368476.3
CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr15_-_63450192 0.66 ENST00000411926.1
RPS27L
ribosomal protein S27-like
chr6_+_44194762 0.65 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr5_+_179921430 0.63 ENST00000393356.1
CNOT6
CCR4-NOT transcription complex, subunit 6
chr1_-_23886285 0.62 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr5_+_140710061 0.61 ENST00000517417.1
ENST00000378105.3
PCDHGA1
protocadherin gamma subfamily A, 1
chr7_-_22234381 0.61 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr16_+_29789561 0.60 ENST00000400752.4
ZG16
zymogen granule protein 16
chr8_-_29120580 0.59 ENST00000524189.1
KIF13B
kinesin family member 13B
chr10_-_104178857 0.58 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr16_+_19183671 0.58 ENST00000562711.2
SYT17
synaptotagmin XVII
chr18_-_25616519 0.56 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr4_+_39699776 0.56 ENST00000503368.1
ENST00000445950.2
UBE2K
ubiquitin-conjugating enzyme E2K
chr7_-_83824169 0.54 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_155107820 0.47 ENST00000484157.1
SLC50A1
solute carrier family 50 (sugar efflux transporter), member 1
chr14_-_23652849 0.46 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chrX_+_49028265 0.46 ENST00000376322.3
ENST00000376327.5
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr3_-_47950745 0.45 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr6_-_86352982 0.45 ENST00000369622.3
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr2_-_152830479 0.44 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr5_+_140588269 0.43 ENST00000541609.1
ENST00000239450.2
PCDHB12
protocadherin beta 12
chr17_+_67498538 0.42 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_-_33168391 0.41 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr16_+_30960375 0.40 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr5_+_72143988 0.40 ENST00000506351.2
TNPO1
transportin 1
chr8_+_134125727 0.39 ENST00000521107.1
TG
thyroglobulin
chr7_+_148892557 0.38 ENST00000262085.3
ZNF282
zinc finger protein 282
chr16_-_18468926 0.37 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr6_+_31582961 0.35 ENST00000376059.3
ENST00000337917.7
AIF1
allograft inflammatory factor 1
chr14_+_24590560 0.35 ENST00000558325.1
RP11-468E2.6
RP11-468E2.6
chr19_+_24009879 0.35 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr1_+_104293028 0.34 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr15_+_71228826 0.33 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr20_+_43935474 0.30 ENST00000372743.1
ENST00000372741.3
ENST00000343694.3
RBPJL
recombination signal binding protein for immunoglobulin kappa J region-like
chr6_+_26251835 0.30 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr10_-_65028817 0.28 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr10_+_103892787 0.26 ENST00000278070.2
ENST00000413464.2
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr1_+_104159999 0.26 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr3_-_88108212 0.21 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr7_-_50633078 0.21 ENST00000444124.2
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr1_+_28764653 0.20 ENST00000373836.3
PHACTR4
phosphatase and actin regulator 4
chr6_+_33168637 0.20 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr17_-_48546232 0.20 ENST00000258969.4
CHAD
chondroadherin
chrX_-_124097620 0.20 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr5_+_179233376 0.19 ENST00000376929.3
ENST00000514093.1
SQSTM1
sequestosome 1
chr10_-_64576105 0.19 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr3_+_69812701 0.18 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr17_-_56492989 0.18 ENST00000583753.1
RNF43
ring finger protein 43
chr4_-_23891693 0.17 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr2_-_174830430 0.16 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr1_-_151804314 0.15 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr2_+_168725458 0.14 ENST00000392690.3
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_-_136743169 0.13 ENST00000264161.4
DARS
aspartyl-tRNA synthetase
chr4_+_106473768 0.13 ENST00000265154.2
ENST00000420470.2
ARHGEF38
Rho guanine nucleotide exchange factor (GEF) 38
chr1_+_57320437 0.13 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chrX_+_107288197 0.09 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr6_+_33168597 0.09 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr17_-_48546324 0.08 ENST00000508540.1
CHAD
chondroadherin
chrX_+_142967173 0.07 ENST00000370494.1
UBE2NL
ubiquitin-conjugating enzyme E2N-like
chr6_+_26045603 0.06 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr5_-_142780280 0.06 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_+_28705921 0.06 ENST00000225719.4
CPD
carboxypeptidase D
chr2_+_234601512 0.06 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr1_+_153700518 0.04 ENST00000318967.2
ENST00000456435.1
ENST00000435409.2
INTS3
integrator complex subunit 3
chr9_+_100745615 0.04 ENST00000339399.4
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr9_-_131038214 0.04 ENST00000609374.1
GOLGA2
golgin A2
chr3_-_149375783 0.03 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr4_-_157892498 0.03 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr5_+_180682720 0.03 ENST00000599439.1
AC008443.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr21_+_34398153 0.02 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
OLIG2
oligodendrocyte lineage transcription factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of DBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
2.5 7.6 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.8 14.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
1.7 5.2 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
1.2 4.8 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
1.2 9.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.1 5.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.1 4.4 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.1 5.4 GO:0097338 response to clozapine(GO:0097338)
1.0 2.9 GO:1901837 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.9 4.4 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.8 2.5 GO:0009447 putrescine catabolic process(GO:0009447)
0.8 3.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.7 5.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 3.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.6 5.1 GO:0030091 protein repair(GO:0030091)
0.6 0.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.5 1.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.5 2.0 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.5 16.4 GO:0090383 phagosome acidification(GO:0090383)
0.5 2.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.4 1.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.4 1.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.4 1.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 4.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 3.8 GO:0042659 regulation of cell fate specification(GO:0042659)
0.3 1.7 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.3 11.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 1.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.3 2.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 1.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 1.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 6.8 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 1.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.9 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.2 3.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 1.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 0.7 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.2 1.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 1.0 GO:0035063 nuclear speck organization(GO:0035063)
0.2 1.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 1.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.2 1.2 GO:0006642 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269)
0.2 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.2 3.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 3.0 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.7 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) synaptic transmission involved in micturition(GO:0060084)
0.2 5.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 4.2 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 1.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.2 0.5 GO:1901656 glycoside transport(GO:1901656)
0.1 6.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 8.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.7 GO:0015862 uridine transport(GO:0015862)
0.1 6.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 1.0 GO:0031269 pseudopodium assembly(GO:0031269)
0.1 0.5 GO:0048880 sensory system development(GO:0048880)
0.1 1.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 4.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.1 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) regulation of aspartic-type peptidase activity(GO:1905245)
0.1 2.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.7 GO:0001554 luteolysis(GO:0001554)
0.1 1.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 1.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 3.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 2.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 3.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 4.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.2 GO:0052314 serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314)
0.1 0.3 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 2.0 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 8.9 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 4.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.4 GO:0015705 iodide transport(GO:0015705)
0.0 0.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.6 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 6.2 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.7 GO:1902260 diaphragm development(GO:0060539) negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 2.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 1.9 GO:0051225 spindle assembly(GO:0051225)
0.0 0.5 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.7 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 2.0 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.8 GO:0034605 cellular response to heat(GO:0034605)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 14.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
1.5 8.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.4 7.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.2 6.0 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.9 9.2 GO:0045180 basal cortex(GO:0045180)
0.7 4.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.7 10.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.6 4.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.6 13.3 GO:0044295 axonal growth cone(GO:0044295)
0.6 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.5 10.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.5 2.9 GO:0001740 Barr body(GO:0001740)
0.5 1.8 GO:0031673 H zone(GO:0031673)
0.4 9.7 GO:0071565 nBAF complex(GO:0071565)
0.4 5.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.3 2.7 GO:0045179 apical cortex(GO:0045179)
0.3 3.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 5.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.8 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.2 1.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 7.6 GO:0031430 M band(GO:0031430)
0.1 7.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 3.5 GO:0071437 invadopodium(GO:0071437)
0.1 1.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 4.0 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.0 GO:0044327 dendritic spine head(GO:0044327)
0.1 4.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.6 GO:0016342 catenin complex(GO:0016342)
0.1 0.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 2.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 1.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.8 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 4.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 6.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.3 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 8.6 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 5.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 5.7 GO:0005770 late endosome(GO:0005770)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 9.1 GO:0031252 cell leading edge(GO:0031252)
0.0 2.3 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 3.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 8.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.0 GO:0070876 SOSS complex(GO:0070876)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 14.4 GO:0043532 angiostatin binding(GO:0043532)
1.0 5.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.9 5.6 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.7 17.9 GO:0002162 dystroglycan binding(GO:0002162)
0.6 7.0 GO:0030274 LIM domain binding(GO:0030274)
0.6 2.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.6 1.7 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.5 6.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 8.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.4 4.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 2.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 1.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.4 1.4 GO:0005046 KDEL sequence binding(GO:0005046)
0.3 5.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.3 4.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.3 2.9 GO:0000182 rDNA binding(GO:0000182)
0.3 1.2 GO:0035473 lipase binding(GO:0035473)
0.3 1.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 1.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 6.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 1.4 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 3.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 4.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 2.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 3.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 5.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 7.1 GO:0030507 spectrin binding(GO:0030507)
0.1 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 4.4 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.3 GO:0016160 amylase activity(GO:0016160)
0.1 3.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.0 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 1.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 10.5 GO:0005262 calcium channel activity(GO:0005262)
0.1 3.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 9.3 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.1 4.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 2.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.6 GO:0005521 lamin binding(GO:0005521)
0.1 1.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.7 GO:0016918 retinal binding(GO:0016918)
0.0 0.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 4.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.7 GO:0070402 NADPH binding(GO:0070402)
0.0 9.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 4.9 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 4.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.7 GO:0046332 SMAD binding(GO:0046332)
0.0 0.5 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 2.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.3 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.5 GO:0019956 chemokine binding(GO:0019956)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.2 GO:0005516 calmodulin binding(GO:0005516)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 14.3 PID LKB1 PATHWAY LKB1 signaling events
0.2 5.4 PID IL3 PATHWAY IL3-mediated signaling events
0.1 7.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 3.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.4 PID ARF 3PATHWAY Arf1 pathway
0.1 4.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 7.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.0 PID FGF PATHWAY FGF signaling pathway
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.6 16.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 5.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 6.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3 3.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 5.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 5.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 5.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 4.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 3.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 0.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 4.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 4.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 1.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 3.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane