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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for DBX2_HLX

Z-value: 0.51

Motif logo

Transcription factors associated with DBX2_HLX

Gene Symbol Gene ID Gene Info
ENSG00000185610.6 developing brain homeobox 2
ENSG00000136630.11 H2.0 like homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLXhg19_v2_chr1_+_221051699_2210516990.064.0e-01Click!

Activity profile of DBX2_HLX motif

Sorted Z-values of DBX2_HLX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_138340049 21.20 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr4_+_113568207 20.78 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr3_+_138340067 13.30 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr8_-_27695552 12.16 ENST00000522944.1
ENST00000301905.4
PDZ binding kinase
chr1_+_81771806 11.45 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr1_-_89357179 11.31 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chr8_+_98900132 10.62 ENST00000520016.1
matrilin 2
chr5_-_146781153 10.45 ENST00000520473.1
dihydropyrimidinase-like 3
chr11_+_35201826 10.27 ENST00000531873.1
CD44 molecule (Indian blood group)
chr1_-_45988542 9.98 ENST00000424390.1
peroxiredoxin 1
chr2_-_10587897 9.36 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr7_-_87856280 9.30 ENST00000490437.1
ENST00000431660.1
sorcin
chr12_-_10978957 9.24 ENST00000240619.2
taste receptor, type 2, member 10
chr3_+_33155525 9.14 ENST00000449224.1
cartilage associated protein
chr7_-_87856303 9.12 ENST00000394641.3
sorcin
chr2_+_187371440 8.77 ENST00000445547.1
zinc finger CCCH-type containing 15
chr2_+_109204909 8.38 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chrX_-_77225135 8.35 ENST00000458128.1
phosphoglycerate mutase family member 4
chr17_+_45728427 7.94 ENST00000540627.1
karyopherin (importin) beta 1
chr6_+_26104104 7.90 ENST00000377803.2
histone cluster 1, H4c
chr16_+_15489603 7.57 ENST00000568766.1
ENST00000287594.7
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chrX_+_56590002 7.44 ENST00000338222.5
ubiquilin 2
chr1_+_224544572 6.99 ENST00000366857.5
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chr3_-_185538849 6.99 ENST00000421047.2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_102413726 6.98 ENST00000350878.4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_87135076 6.62 ENST00000409776.2
RANBP2-like and GRIP domain containing 1
chr6_+_34204642 6.60 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr17_-_8113542 6.53 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr14_+_53173910 6.53 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr3_-_141719195 6.50 ENST00000397991.4
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_-_64023441 6.48 ENST00000309683.6
zinc finger protein 680
chr2_-_17981462 6.40 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr6_+_34725263 6.38 ENST00000374018.1
ENST00000374017.3
small nuclear ribonucleoprotein polypeptide C
chr14_+_53173890 6.33 ENST00000445930.2
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr3_-_141747950 6.32 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr8_-_13134045 6.22 ENST00000512044.2
deleted in liver cancer 1
chr15_+_64680003 6.20 ENST00000261884.3
thyroid hormone receptor interactor 4
chr2_+_201936707 6.07 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr22_+_42017987 5.86 ENST00000405506.1
X-ray repair complementing defective repair in Chinese hamster cells 6
chr12_+_104337515 5.82 ENST00000550595.1
heat shock protein 90kDa beta (Grp94), member 1
chr7_-_5998714 5.78 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr17_+_35851570 5.78 ENST00000394386.1
dual specificity phosphatase 14
chr16_+_24549014 5.76 ENST00000564314.1
ENST00000567686.1
retinoblastoma binding protein 6
chr2_+_109204743 5.66 ENST00000332345.6
LIM and senescent cell antigen-like domains 1
chr6_-_8102279 5.55 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr6_+_89674246 5.52 ENST00000369474.1
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr1_-_110950564 5.46 ENST00000256644.4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr2_+_161993412 5.26 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr7_+_130126165 5.16 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
mesoderm specific transcript
chr1_-_54411255 5.02 ENST00000371377.3
heat shock protein family B (small), member 11
chr12_+_64798095 4.94 ENST00000332707.5
exportin, tRNA
chrX_-_16887963 4.87 ENST00000380084.4
retinoblastoma binding protein 7
chr4_-_103746683 4.83 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr11_-_18548426 4.82 ENST00000357193.3
ENST00000536719.1
tumor susceptibility 101
chr22_-_29107919 4.80 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr8_+_132952112 4.79 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chrX_-_106243451 4.77 ENST00000355610.4
ENST00000535534.1
MORC family CW-type zinc finger 4
chr12_+_20963632 4.76 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr10_-_95242044 4.73 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr5_+_115177178 4.66 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr8_-_101719159 4.65 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr15_+_65843130 4.65 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr1_-_212965104 4.63 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1, MIS12 kinetochore complex component
chr12_+_20963647 4.60 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr11_-_107729887 4.60 ENST00000525815.1
solute carrier family 35, member F2
chr10_-_95241951 4.59 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr5_+_82767284 4.58 ENST00000265077.3
versican
chr9_+_12693336 4.53 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr20_-_33735070 4.49 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
ER degradation enhancer, mannosidase alpha-like 2
chr1_-_153643442 4.40 ENST00000368681.1
ENST00000361891.4
interleukin enhancer binding factor 2
chr12_+_75874460 4.27 ENST00000266659.3
GLI pathogenesis-related 1
chr5_+_82767487 4.27 ENST00000343200.5
ENST00000342785.4
versican
chr7_+_107224364 4.20 ENST00000491150.1
B-cell receptor-associated protein 29
chr3_+_160939050 4.19 ENST00000493066.1
ENST00000351193.2
ENST00000472947.1
ENST00000463518.1
NMD3 ribosome export adaptor
chr16_-_28634874 4.14 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_-_135962876 4.04 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr7_+_130126012 4.03 ENST00000341441.5
mesoderm specific transcript
chr10_+_62538089 3.98 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr12_+_123237321 3.97 ENST00000280557.6
ENST00000455982.2
density-regulated protein
chr2_+_109237717 3.90 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr1_+_84630645 3.88 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_60142609 3.81 ENST00000397786.2
mediator complex subunit 13
chr4_+_41540160 3.78 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chr14_-_78083112 3.77 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr2_-_113594279 3.76 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr11_-_63376013 3.73 ENST00000540943.1
phospholipase A2, group XVI
chr11_-_10828892 3.69 ENST00000525681.1
eukaryotic translation initiation factor 4 gamma, 2
chr9_+_125132803 3.68 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_+_8191815 3.63 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr8_+_31497271 3.60 ENST00000520407.1
neuregulin 1
chr1_+_76251879 3.56 ENST00000535300.1
ENST00000319942.3
Rab geranylgeranyltransferase, beta subunit
chr3_+_136649311 3.55 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr21_-_18985230 3.55 ENST00000457956.1
ENST00000348354.6
BTG family, member 3
chr15_+_67418047 3.54 ENST00000540846.2
SMAD family member 3
chr2_+_109223595 3.53 ENST00000410093.1
LIM and senescent cell antigen-like domains 1
chr3_+_139063372 3.53 ENST00000478464.1
mitochondrial ribosomal protein S22
chr3_-_123512688 3.53 ENST00000475616.1
myosin light chain kinase
chr14_-_35591433 3.50 ENST00000261475.5
ENST00000555644.1
protein phosphatase 2, regulatory subunit B'', gamma
chr9_-_70465758 3.47 ENST00000489273.1
COBW domain containing 5
chr9_-_2844058 3.47 ENST00000397885.2
KIAA0020
chr11_+_101983176 3.45 ENST00000524575.1
Yes-associated protein 1
chr5_-_68665084 3.45 ENST00000509462.1
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr8_-_101718991 3.42 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr11_-_104827425 3.40 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr20_-_1447467 3.39 ENST00000353088.2
ENST00000350991.4
NSFL1 (p97) cofactor (p47)
chr12_-_7656357 3.39 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163 molecule
chr2_-_55496174 3.33 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr20_-_1447547 3.33 ENST00000476071.1
NSFL1 (p97) cofactor (p47)
chr7_+_134576317 3.32 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chrX_-_114252193 3.29 ENST00000243213.1
interleukin 13 receptor, alpha 2
chr2_-_145277569 3.24 ENST00000303660.4
zinc finger E-box binding homeobox 2
chrX_-_102942961 3.15 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
mortality factor 4 like 2
chr6_+_114178512 3.14 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr11_-_59950486 3.12 ENST00000426738.2
ENST00000533023.1
ENST00000420732.2
membrane-spanning 4-domains, subfamily A, member 6A
chr8_-_141774467 3.11 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr14_+_35591928 3.09 ENST00000605870.1
ENST00000557404.3
KIAA0391
chr7_+_116654935 2.97 ENST00000432298.1
ENST00000422922.1
suppression of tumorigenicity 7
chr20_+_1099233 2.96 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr16_+_14802801 2.95 ENST00000526520.1
ENST00000531598.2
nuclear pore complex interacting protein family, member A3
chr12_+_75874580 2.94 ENST00000456650.3
GLI pathogenesis-related 1
chr20_+_11871433 2.94 ENST00000399006.2
ENST00000405977.1
BTB (POZ) domain containing 3
chr20_+_11871371 2.94 ENST00000254977.3
BTB (POZ) domain containing 3
chr6_+_153552455 2.93 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr19_-_13044494 2.92 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
phenylalanyl-tRNA synthetase, alpha subunit
chr3_+_158787041 2.88 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr1_-_110283138 2.87 ENST00000256594.3
glutathione S-transferase mu 3 (brain)
chr7_-_140714739 2.86 ENST00000467334.1
ENST00000324787.5
mitochondrial ribosomal protein S33
chr19_-_43382142 2.83 ENST00000597058.1
pregnancy specific beta-1-glycoprotein 1
chr7_+_134576151 2.79 ENST00000393118.2
caldesmon 1
chr2_-_58468437 2.77 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
Fanconi anemia, complementation group L
chr11_-_327537 2.76 ENST00000602735.1
interferon induced transmembrane protein 3
chr12_+_75874984 2.75 ENST00000550491.1
GLI pathogenesis-related 1
chr7_-_139763521 2.75 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chrX_-_100662881 2.73 ENST00000218516.3
galactosidase, alpha
chrX_-_102943022 2.73 ENST00000433176.2
mortality factor 4 like 2
chr9_-_21305312 2.69 ENST00000259555.4
interferon, alpha 5
chr2_-_88285309 2.67 ENST00000420840.2
RANBP2-like and GRIP domain containing 2
chr5_+_95066823 2.65 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr1_-_145826450 2.59 ENST00000462900.2
G protein-coupled receptor 89A
chr2_-_191115229 2.58 ENST00000409820.2
ENST00000410045.1
3-hydroxyisobutyryl-CoA hydrolase
chr7_+_129932974 2.58 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chr2_-_37544209 2.57 ENST00000234179.2
protein kinase D3
chr5_-_10761206 2.56 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr8_-_49834299 2.55 ENST00000396822.1
snail family zinc finger 2
chr16_-_28222797 2.54 ENST00000569951.1
ENST00000565698.1
exportin 6
chr10_+_79793518 2.49 ENST00000440692.1
ENST00000435275.1
ENST00000372360.3
ENST00000360830.4
ribosomal protein S24
chr2_+_6111712 2.48 ENST00000391666.2
HCG1990367; Putative uncharacterized protein DKFZp761K2322; Putative uncharacterized protein FLJ30594; Uncharacterized protein; cDNA FLJ30594 fis, clone BRAWH2008903
chr5_+_67588391 2.47 ENST00000523872.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_-_49833978 2.47 ENST00000020945.1
snail family zinc finger 2
chr3_+_157827841 2.44 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
arginine/serine-rich coiled-coil 1
chr6_+_34725181 2.42 ENST00000244520.5
small nuclear ribonucleoprotein polypeptide C
chr17_-_55038375 2.39 ENST00000240316.4
coilin
chr12_+_10658201 2.36 ENST00000322446.3
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr5_-_139726181 2.35 ENST00000507104.1
ENST00000230990.6
heparin-binding EGF-like growth factor
chr2_+_103089756 2.35 ENST00000295269.4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr4_-_164534657 2.32 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr2_+_86669118 2.30 ENST00000427678.1
ENST00000542128.1
lysine (K)-specific demethylase 3A
chr5_-_34916871 2.29 ENST00000382038.2
RAD1 homolog (S. pombe)
chr11_+_110300607 2.29 ENST00000260270.2
ferredoxin 1
chr7_-_22862406 2.29 ENST00000372879.4
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr16_-_29934558 2.27 ENST00000568995.1
ENST00000566413.1
potassium channel tetramerization domain containing 13
chr10_-_112678692 2.27 ENST00000605742.1
BBSome interacting protein 1
chr15_-_42749711 2.26 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
zinc finger protein 106
chr10_-_112678904 2.26 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBSome interacting protein 1
chr14_+_39583427 2.25 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
gem (nuclear organelle) associated protein 2
chr14_+_89060749 2.24 ENST00000555900.1
ENST00000406216.3
ENST00000557737.1
zinc finger CCCH-type containing 14
chr1_-_197036364 2.22 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr2_+_169312350 2.21 ENST00000305747.6
ceramide synthase 6
chr8_+_11666649 2.19 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr10_+_122610687 2.16 ENST00000263461.6
WD repeat domain 11
chr12_+_10658489 2.15 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr14_+_89060739 2.14 ENST00000318308.6
zinc finger CCCH-type containing 14
chr10_-_94257512 2.05 ENST00000371581.5
insulin-degrading enzyme
chr11_-_59950519 2.05 ENST00000528851.1
membrane-spanning 4-domains, subfamily A, member 6A
chr2_+_11674213 2.05 ENST00000381486.2
growth regulation by estrogen in breast cancer 1
chr6_-_75960024 2.01 ENST00000370081.2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr6_+_158733692 2.00 ENST00000367094.2
ENST00000367097.3
tubby like protein 4
chr11_-_104817919 1.96 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr11_+_2405833 1.95 ENST00000527343.1
ENST00000464784.2
CD81 molecule
chr2_-_37068530 1.95 ENST00000593798.1
Uncharacterized protein
chr4_+_41937131 1.94 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
transmembrane protein 33
chr8_-_54752406 1.94 ENST00000520188.1
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr9_-_21217310 1.93 ENST00000380216.1
interferon, alpha 16
chr11_+_44117099 1.92 ENST00000533608.1
exostosin glycosyltransferase 2
chr4_+_147096837 1.92 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_-_11685345 1.90 ENST00000430365.2
vestigial like 4 (Drosophila)
chr4_+_69962212 1.87 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr20_-_7921090 1.86 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr1_-_35450897 1.86 ENST00000373337.3
ZMYM6 neighbor
chrX_+_100663243 1.85 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr19_+_54466179 1.84 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr1_-_21377383 1.83 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr4_-_48782259 1.82 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRY-like
chr4_+_69962185 1.82 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chrX_-_119445306 1.82 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
transmembrane protein 255A
chr2_-_70520539 1.80 ENST00000482975.2
ENST00000438261.1
small nuclear ribonucleoprotein polypeptide G
chr17_+_67498538 1.80 ENST00000589647.1
mitogen-activated protein kinase kinase 6
chr11_+_45825616 1.77 ENST00000442528.2
ENST00000456334.1
ENST00000526817.1
solute carrier family 35 (GDP-fucose transporter), member C1
chr5_-_125930929 1.76 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr10_+_51572339 1.75 ENST00000344348.6
nuclear receptor coactivator 4

Network of associatons between targets according to the STRING database.

First level regulatory network of DBX2_HLX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:1901873 regulation of post-translational protein modification(GO:1901873)
2.6 18.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.3 9.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
2.2 6.5 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
2.1 8.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.0 7.9 GO:0031291 Ran protein signal transduction(GO:0031291)
1.9 7.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
1.9 11.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
1.9 3.8 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.9 7.4 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.7 1.7 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.7 5.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.7 6.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
1.6 4.8 GO:2000397 ubiquitin-dependent endocytosis(GO:0070086) regulation of viral budding via host ESCRT complex(GO:1903772) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
1.6 4.8 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.5 4.5 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
1.4 4.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
1.3 4.0 GO:0002188 translation reinitiation(GO:0002188)
1.3 10.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.2 3.5 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
1.1 6.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.0 8.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
1.0 5.9 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
1.0 4.9 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.9 3.8 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.9 3.6 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.9 8.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.9 7.8 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.8 9.3 GO:0001778 plasma membrane repair(GO:0001778)
0.8 1.6 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.8 3.9 GO:0097338 response to clozapine(GO:0097338)
0.8 2.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.8 4.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.7 2.9 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.7 3.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.7 2.1 GO:1901143 insulin catabolic process(GO:1901143)
0.7 4.0 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.6 1.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.6 13.6 GO:0051764 actin crosslink formation(GO:0051764)
0.6 1.9 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.6 2.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.6 6.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.6 1.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.6 1.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.6 5.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.6 1.8 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.6 2.9 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.6 2.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.6 3.3 GO:0032790 ribosome disassembly(GO:0032790)
0.5 3.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.5 1.6 GO:0097052 tryptophan catabolic process to acetyl-CoA(GO:0019442) L-kynurenine metabolic process(GO:0097052)
0.5 2.6 GO:0006574 valine catabolic process(GO:0006574)
0.5 3.6 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.5 12.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.5 1.9 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.5 17.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.5 6.0 GO:0070986 left/right axis specification(GO:0070986)
0.4 3.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 2.2 GO:0097384 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) cellular lipid biosynthetic process(GO:0097384)
0.4 3.5 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.4 1.7 GO:0005997 xylulose metabolic process(GO:0005997)
0.4 1.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.4 4.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 5.8 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.4 6.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.4 1.7 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.4 10.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 5.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.4 3.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.4 4.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.4 2.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.4 3.5 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.4 6.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 3.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.3 2.7 GO:0016139 glycoside catabolic process(GO:0016139)
0.3 11.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.3 0.3 GO:0051180 vitamin transport(GO:0051180)
0.3 9.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 1.0 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3 7.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 7.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 1.5 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.3 4.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.3 4.7 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 12.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 0.8 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.3 3.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 1.1 GO:1903960 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) plasma membrane long-chain fatty acid transport(GO:0015911) negative regulation of anion transmembrane transport(GO:1903960)
0.3 4.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 1.3 GO:0071233 cellular response to leucine(GO:0071233)
0.3 1.8 GO:0042426 choline catabolic process(GO:0042426)
0.2 6.0 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.2 0.7 GO:0006772 thiamine metabolic process(GO:0006772)
0.2 10.5 GO:0015721 bile acid and bile salt transport(GO:0015721) sodium-independent organic anion transport(GO:0043252)
0.2 1.7 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.2 0.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 8.9 GO:0061462 protein localization to lysosome(GO:0061462)
0.2 3.3 GO:0002638 negative regulation of immunoglobulin production(GO:0002638)
0.2 6.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 13.4 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.2 2.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.2 2.5 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.2 0.8 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 1.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 2.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 1.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.2 1.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.7 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 1.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 1.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 1.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 10.6 GO:0008347 glial cell migration(GO:0008347)
0.2 1.0 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.6 GO:2000111 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of macrophage apoptotic process(GO:2000111)
0.2 5.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 1.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 2.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 1.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 9.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 2.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.5 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 2.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.5 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 8.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.8 GO:0008218 bioluminescence(GO:0008218)
0.1 2.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 2.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.8 GO:0090527 actin filament reorganization(GO:0090527)
0.1 4.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 4.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 3.4 GO:0008209 androgen metabolic process(GO:0008209)
0.1 0.5 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 1.4 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:0019321 pentose metabolic process(GO:0019321)
0.1 4.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 2.9 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 0.4 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.1 5.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 6.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 4.5 GO:0051452 intracellular pH reduction(GO:0051452)
0.1 3.6 GO:0061053 somite development(GO:0061053)
0.1 3.9 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 1.3 GO:0033622 integrin activation(GO:0033622)
0.1 0.5 GO:0006063 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585)
0.1 2.0 GO:0061512 protein localization to cilium(GO:0061512)
0.1 0.9 GO:0001501 skeletal system development(GO:0001501)
0.1 0.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.5 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.2 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 7.3 GO:0007498 mesoderm development(GO:0007498)
0.1 1.0 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 9.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 2.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.7 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 2.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.8 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 3.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 4.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.0 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 4.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 1.4 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.7 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0015816 glycine transport(GO:0015816)
0.0 1.5 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 1.9 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 1.0 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 1.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 5.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 3.7 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 3.0 GO:0016573 histone acetylation(GO:0016573)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.9 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 1.6 GO:0006413 translational initiation(GO:0006413)
0.0 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0006953 acute-phase response(GO:0006953)
0.0 1.4 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 2.7 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 1.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.4 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.6 GO:0007566 embryo implantation(GO:0007566)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.4 GO:0044326 dendritic spine neck(GO:0044326)
1.7 6.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
1.6 6.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
1.5 10.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.2 5.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.1 5.6 GO:0044530 supraspliceosomal complex(GO:0044530)
1.1 5.5 GO:0071986 Ragulator complex(GO:0071986)
1.1 12.9 GO:0031595 nuclear proteasome complex(GO:0031595)
1.0 10.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.9 3.8 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.9 4.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.9 4.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.9 5.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.9 3.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.8 6.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.8 4.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.7 2.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.7 3.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.7 4.8 GO:0000813 ESCRT I complex(GO:0000813)
0.7 8.8 GO:0000243 commitment complex(GO:0000243)
0.6 2.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.6 6.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 2.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.5 10.2 GO:0005604 basement membrane(GO:0005604)
0.5 1.9 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.4 3.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.4 4.0 GO:0034464 BBSome(GO:0034464)
0.4 3.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.4 8.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 4.7 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.4 6.1 GO:0030478 actin cap(GO:0030478)
0.4 7.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 2.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 1.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.3 2.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.3 1.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 8.4 GO:0097228 sperm principal piece(GO:0097228)
0.3 1.8 GO:0005683 U7 snRNP(GO:0005683)
0.3 5.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 2.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.3 5.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 5.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 2.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.3 5.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 4.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 6.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 3.5 GO:0044754 autolysosome(GO:0044754)
0.2 7.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 1.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 4.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 1.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 3.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 11.8 GO:0031941 filamentous actin(GO:0031941)
0.2 3.1 GO:0043073 germ cell nucleus(GO:0043073)
0.2 4.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.9 GO:0005688 U6 snRNP(GO:0005688)
0.2 18.1 GO:0005901 caveola(GO:0005901)
0.1 1.2 GO:0070552 BRISC complex(GO:0070552)
0.1 1.7 GO:0043219 lateral loop(GO:0043219)
0.1 4.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 1.7 GO:0005916 fascia adherens(GO:0005916)
0.1 10.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 8.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.3 GO:0071141 SMAD protein complex(GO:0071141)
0.1 5.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.8 GO:0016592 mediator complex(GO:0016592)
0.1 7.4 GO:0005776 autophagosome(GO:0005776)
0.1 1.6 GO:0031932 TORC2 complex(GO:0031932)
0.1 3.0 GO:0005839 proteasome core complex(GO:0005839)
0.1 3.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 2.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 5.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 5.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 11.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 5.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.3 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 6.4 GO:0005643 nuclear pore(GO:0005643)
0.1 5.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146) filopodium tip(GO:0032433)
0.1 2.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 3.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 4.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.3 GO:0005921 gap junction(GO:0005921)
0.0 9.4 GO:0043209 myelin sheath(GO:0043209)
0.0 1.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 4.0 GO:0005840 ribosome(GO:0005840)
0.0 3.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.8 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 10.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 17.9 GO:0005925 focal adhesion(GO:0005925)
0.0 4.0 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0044439 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 1.5 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 10.8 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 14.9 GO:0005730 nucleolus(GO:0005730)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 1.7 GO:0043197 dendritic spine(GO:0043197)
0.0 1.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.5 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 4.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 3.6 GO:0010008 endosome membrane(GO:0010008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
2.1 8.4 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.4 5.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.3 3.8 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.2 10.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.2 9.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.2 12.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.1 6.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.0 10.8 GO:0033038 bitter taste receptor activity(GO:0033038)
1.0 10.6 GO:0046790 virion binding(GO:0046790)
0.9 7.0 GO:0004111 creatine kinase activity(GO:0004111)
0.8 4.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.8 3.8 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.7 3.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.7 2.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.7 6.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.7 3.6 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.7 3.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.7 3.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.7 3.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.7 7.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.7 2.7 GO:0016936 galactoside binding(GO:0016936)
0.6 4.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.6 1.8 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.6 17.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 5.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.6 4.5 GO:0043559 insulin binding(GO:0043559)
0.5 2.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.5 3.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.5 1.5 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.5 1.9 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.5 10.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.5 8.1 GO:0008494 translation activator activity(GO:0008494)
0.5 6.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 16.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 1.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.4 1.6 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4 5.4 GO:0050700 CARD domain binding(GO:0050700)
0.4 2.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.4 5.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 2.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.4 16.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 10.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.4 3.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 3.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 0.9 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.2 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3 1.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 4.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 1.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.3 3.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 0.8 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.3 3.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 3.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 1.3 GO:0070728 leucine binding(GO:0070728)
0.2 0.7 GO:0004802 transketolase activity(GO:0004802)
0.2 2.3 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 6.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 7.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 1.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 6.1 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 14.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 2.3 GO:0015266 protein channel activity(GO:0015266)
0.2 1.7 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 3.1 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 2.9 GO:0043295 glutathione binding(GO:0043295)
0.2 4.4 GO:0008143 poly(A) binding(GO:0008143)
0.2 4.0 GO:0035173 histone kinase activity(GO:0035173)
0.2 0.7 GO:0035473 lipase binding(GO:0035473)
0.2 1.7 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 9.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 2.0 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.2 2.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 2.6 GO:0070513 death domain binding(GO:0070513)
0.2 2.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 1.7 GO:0097016 L27 domain binding(GO:0097016)
0.1 3.0 GO:0070628 proteasome binding(GO:0070628)
0.1 1.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 2.6 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 1.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 6.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 2.6 GO:0004697 protein kinase C activity(GO:0004697)
0.1 2.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 2.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 7.0 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 3.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 3.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 4.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.5 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 4.7 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 4.7 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 4.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.4 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 11.0 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 2.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 1.1 GO:0008201 heparin binding(GO:0008201)
0.1 2.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors