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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for DBX2_HLX

Z-value: 0.51

Motif logo

Transcription factors associated with DBX2_HLX

Gene Symbol Gene ID Gene Info
ENSG00000185610.6 developing brain homeobox 2
ENSG00000136630.11 H2.0 like homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLXhg19_v2_chr1_+_221051699_2210516990.064.0e-01Click!

Activity profile of DBX2_HLX motif

Sorted Z-values of DBX2_HLX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_138340049 21.20 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr4_+_113568207 20.78 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr3_+_138340067 13.30 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr8_-_27695552 12.16 ENST00000522944.1
ENST00000301905.4
PDZ binding kinase
chr1_+_81771806 11.45 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr1_-_89357179 11.31 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chr8_+_98900132 10.62 ENST00000520016.1
matrilin 2
chr5_-_146781153 10.45 ENST00000520473.1
dihydropyrimidinase-like 3
chr11_+_35201826 10.27 ENST00000531873.1
CD44 molecule (Indian blood group)
chr1_-_45988542 9.98 ENST00000424390.1
peroxiredoxin 1
chr2_-_10587897 9.36 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr7_-_87856280 9.30 ENST00000490437.1
ENST00000431660.1
sorcin
chr12_-_10978957 9.24 ENST00000240619.2
taste receptor, type 2, member 10
chr3_+_33155525 9.14 ENST00000449224.1
cartilage associated protein
chr7_-_87856303 9.12 ENST00000394641.3
sorcin
chr2_+_187371440 8.77 ENST00000445547.1
zinc finger CCCH-type containing 15
chr2_+_109204909 8.38 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chrX_-_77225135 8.35 ENST00000458128.1
phosphoglycerate mutase family member 4
chr17_+_45728427 7.94 ENST00000540627.1
karyopherin (importin) beta 1
chr6_+_26104104 7.90 ENST00000377803.2
histone cluster 1, H4c
chr16_+_15489603 7.57 ENST00000568766.1
ENST00000287594.7
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chrX_+_56590002 7.44 ENST00000338222.5
ubiquilin 2
chr1_+_224544572 6.99 ENST00000366857.5
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chr3_-_185538849 6.99 ENST00000421047.2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_102413726 6.98 ENST00000350878.4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_87135076 6.62 ENST00000409776.2
RANBP2-like and GRIP domain containing 1
chr6_+_34204642 6.60 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr17_-_8113542 6.53 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr14_+_53173910 6.53 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr3_-_141719195 6.50 ENST00000397991.4
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_-_64023441 6.48 ENST00000309683.6
zinc finger protein 680
chr2_-_17981462 6.40 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr6_+_34725263 6.38 ENST00000374018.1
ENST00000374017.3
small nuclear ribonucleoprotein polypeptide C
chr14_+_53173890 6.33 ENST00000445930.2
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr3_-_141747950 6.32 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr8_-_13134045 6.22 ENST00000512044.2
deleted in liver cancer 1
chr15_+_64680003 6.20 ENST00000261884.3
thyroid hormone receptor interactor 4
chr2_+_201936707 6.07 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr22_+_42017987 5.86 ENST00000405506.1
X-ray repair complementing defective repair in Chinese hamster cells 6
chr12_+_104337515 5.82 ENST00000550595.1
heat shock protein 90kDa beta (Grp94), member 1
chr7_-_5998714 5.78 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr17_+_35851570 5.78 ENST00000394386.1
dual specificity phosphatase 14
chr16_+_24549014 5.76 ENST00000564314.1
ENST00000567686.1
retinoblastoma binding protein 6
chr2_+_109204743 5.66 ENST00000332345.6
LIM and senescent cell antigen-like domains 1
chr6_-_8102279 5.55 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr6_+_89674246 5.52 ENST00000369474.1
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr1_-_110950564 5.46 ENST00000256644.4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr2_+_161993412 5.26 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr7_+_130126165 5.16 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
mesoderm specific transcript
chr1_-_54411255 5.02 ENST00000371377.3
heat shock protein family B (small), member 11
chr12_+_64798095 4.94 ENST00000332707.5
exportin, tRNA
chrX_-_16887963 4.87 ENST00000380084.4
retinoblastoma binding protein 7
chr4_-_103746683 4.83 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr11_-_18548426 4.82 ENST00000357193.3
ENST00000536719.1
tumor susceptibility 101
chr22_-_29107919 4.80 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr8_+_132952112 4.79 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chrX_-_106243451 4.77 ENST00000355610.4
ENST00000535534.1
MORC family CW-type zinc finger 4
chr12_+_20963632 4.76 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr10_-_95242044 4.73 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr5_+_115177178 4.66 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr8_-_101719159 4.65 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr15_+_65843130 4.65 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr1_-_212965104 4.63 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1, MIS12 kinetochore complex component
chr12_+_20963647 4.60 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr11_-_107729887 4.60 ENST00000525815.1
solute carrier family 35, member F2
chr10_-_95241951 4.59 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr5_+_82767284 4.58 ENST00000265077.3
versican
chr9_+_12693336 4.53 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr20_-_33735070 4.49 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
ER degradation enhancer, mannosidase alpha-like 2
chr1_-_153643442 4.40 ENST00000368681.1
ENST00000361891.4
interleukin enhancer binding factor 2
chr12_+_75874460 4.27 ENST00000266659.3
GLI pathogenesis-related 1
chr5_+_82767487 4.27 ENST00000343200.5
ENST00000342785.4
versican
chr7_+_107224364 4.20 ENST00000491150.1
B-cell receptor-associated protein 29
chr3_+_160939050 4.19 ENST00000493066.1
ENST00000351193.2
ENST00000472947.1
ENST00000463518.1
NMD3 ribosome export adaptor
chr16_-_28634874 4.14 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_-_135962876 4.04 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr7_+_130126012 4.03 ENST00000341441.5
mesoderm specific transcript
chr10_+_62538089 3.98 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr12_+_123237321 3.97 ENST00000280557.6
ENST00000455982.2
density-regulated protein
chr2_+_109237717 3.90 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr1_+_84630645 3.88 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_60142609 3.81 ENST00000397786.2
mediator complex subunit 13
chr4_+_41540160 3.78 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chr14_-_78083112 3.77 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr2_-_113594279 3.76 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr11_-_63376013 3.73 ENST00000540943.1
phospholipase A2, group XVI
chr11_-_10828892 3.69 ENST00000525681.1
eukaryotic translation initiation factor 4 gamma, 2
chr9_+_125132803 3.68 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_+_8191815 3.63 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr8_+_31497271 3.60 ENST00000520407.1
neuregulin 1
chr1_+_76251879 3.56 ENST00000535300.1
ENST00000319942.3
Rab geranylgeranyltransferase, beta subunit
chr3_+_136649311 3.55 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr21_-_18985230 3.55 ENST00000457956.1
ENST00000348354.6
BTG family, member 3
chr15_+_67418047 3.54 ENST00000540846.2
SMAD family member 3
chr2_+_109223595 3.53 ENST00000410093.1
LIM and senescent cell antigen-like domains 1
chr3_+_139063372 3.53 ENST00000478464.1
mitochondrial ribosomal protein S22
chr3_-_123512688 3.53 ENST00000475616.1
myosin light chain kinase
chr14_-_35591433 3.50 ENST00000261475.5
ENST00000555644.1
protein phosphatase 2, regulatory subunit B'', gamma
chr9_-_70465758 3.47 ENST00000489273.1
COBW domain containing 5
chr9_-_2844058 3.47 ENST00000397885.2
KIAA0020
chr11_+_101983176 3.45 ENST00000524575.1
Yes-associated protein 1
chr5_-_68665084 3.45 ENST00000509462.1
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr8_-_101718991 3.42 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr11_-_104827425 3.40 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr20_-_1447467 3.39 ENST00000353088.2
ENST00000350991.4
NSFL1 (p97) cofactor (p47)
chr12_-_7656357 3.39 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163 molecule
chr2_-_55496174 3.33 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr20_-_1447547 3.33 ENST00000476071.1
NSFL1 (p97) cofactor (p47)
chr7_+_134576317 3.32 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chrX_-_114252193 3.29 ENST00000243213.1
interleukin 13 receptor, alpha 2
chr2_-_145277569 3.24 ENST00000303660.4
zinc finger E-box binding homeobox 2
chrX_-_102942961 3.15 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
mortality factor 4 like 2
chr6_+_114178512 3.14 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr11_-_59950486 3.12 ENST00000426738.2
ENST00000533023.1
ENST00000420732.2
membrane-spanning 4-domains, subfamily A, member 6A
chr8_-_141774467 3.11 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr14_+_35591928 3.09 ENST00000605870.1
ENST00000557404.3
KIAA0391
chr7_+_116654935 2.97 ENST00000432298.1
ENST00000422922.1
suppression of tumorigenicity 7
chr20_+_1099233 2.96 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr16_+_14802801 2.95 ENST00000526520.1
ENST00000531598.2
nuclear pore complex interacting protein family, member A3
chr12_+_75874580 2.94 ENST00000456650.3
GLI pathogenesis-related 1
chr20_+_11871433 2.94 ENST00000399006.2
ENST00000405977.1
BTB (POZ) domain containing 3
chr20_+_11871371 2.94 ENST00000254977.3
BTB (POZ) domain containing 3
chr6_+_153552455 2.93 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr19_-_13044494 2.92 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
phenylalanyl-tRNA synthetase, alpha subunit
chr3_+_158787041 2.88 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr1_-_110283138 2.87 ENST00000256594.3
glutathione S-transferase mu 3 (brain)
chr7_-_140714739 2.86 ENST00000467334.1
ENST00000324787.5
mitochondrial ribosomal protein S33
chr19_-_43382142 2.83 ENST00000597058.1
pregnancy specific beta-1-glycoprotein 1
chr7_+_134576151 2.79 ENST00000393118.2
caldesmon 1
chr2_-_58468437 2.77 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
Fanconi anemia, complementation group L
chr11_-_327537 2.76 ENST00000602735.1
interferon induced transmembrane protein 3
chr12_+_75874984 2.75 ENST00000550491.1
GLI pathogenesis-related 1
chr7_-_139763521 2.75 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chrX_-_100662881 2.73 ENST00000218516.3
galactosidase, alpha
chrX_-_102943022 2.73 ENST00000433176.2
mortality factor 4 like 2
chr9_-_21305312 2.69 ENST00000259555.4
interferon, alpha 5
chr2_-_88285309 2.67 ENST00000420840.2
RANBP2-like and GRIP domain containing 2
chr5_+_95066823 2.65 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr1_-_145826450 2.59 ENST00000462900.2
G protein-coupled receptor 89A
chr2_-_191115229 2.58 ENST00000409820.2
ENST00000410045.1
3-hydroxyisobutyryl-CoA hydrolase
chr7_+_129932974 2.58 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chr2_-_37544209 2.57 ENST00000234179.2
protein kinase D3
chr5_-_10761206 2.56 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr8_-_49834299 2.55 ENST00000396822.1
snail family zinc finger 2
chr16_-_28222797 2.54 ENST00000569951.1
ENST00000565698.1
exportin 6
chr10_+_79793518 2.49 ENST00000440692.1
ENST00000435275.1
ENST00000372360.3
ENST00000360830.4
ribosomal protein S24
chr2_+_6111712 2.48 ENST00000391666.2
HCG1990367; Putative uncharacterized protein DKFZp761K2322; Putative uncharacterized protein FLJ30594; Uncharacterized protein; cDNA FLJ30594 fis, clone BRAWH2008903
chr5_+_67588391 2.47 ENST00000523872.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_-_49833978 2.47 ENST00000020945.1
snail family zinc finger 2
chr3_+_157827841 2.44 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
arginine/serine-rich coiled-coil 1
chr6_+_34725181 2.42 ENST00000244520.5
small nuclear ribonucleoprotein polypeptide C
chr17_-_55038375 2.39 ENST00000240316.4
coilin
chr12_+_10658201 2.36 ENST00000322446.3
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr5_-_139726181 2.35 ENST00000507104.1
ENST00000230990.6
heparin-binding EGF-like growth factor
chr2_+_103089756 2.35 ENST00000295269.4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr4_-_164534657 2.32 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr2_+_86669118 2.30 ENST00000427678.1
ENST00000542128.1
lysine (K)-specific demethylase 3A
chr5_-_34916871 2.29 ENST00000382038.2
RAD1 homolog (S. pombe)
chr11_+_110300607 2.29 ENST00000260270.2
ferredoxin 1
chr7_-_22862406 2.29 ENST00000372879.4
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr16_-_29934558 2.27 ENST00000568995.1
ENST00000566413.1
potassium channel tetramerization domain containing 13
chr10_-_112678692 2.27 ENST00000605742.1
BBSome interacting protein 1
chr15_-_42749711 2.26 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
zinc finger protein 106
chr10_-_112678904 2.26 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBSome interacting protein 1
chr14_+_39583427 2.25 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
gem (nuclear organelle) associated protein 2
chr14_+_89060749 2.24 ENST00000555900.1
ENST00000406216.3
ENST00000557737.1
zinc finger CCCH-type containing 14
chr1_-_197036364 2.22 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr2_+_169312350 2.21 ENST00000305747.6
ceramide synthase 6
chr8_+_11666649 2.19 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr10_+_122610687 2.16 ENST00000263461.6
WD repeat domain 11
chr12_+_10658489 2.15 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr14_+_89060739 2.14 ENST00000318308.6
zinc finger CCCH-type containing 14
chr10_-_94257512 2.05 ENST00000371581.5
insulin-degrading enzyme
chr11_-_59950519 2.05 ENST00000528851.1
membrane-spanning 4-domains, subfamily A, member 6A
chr2_+_11674213 2.05 ENST00000381486.2
growth regulation by estrogen in breast cancer 1
chr6_-_75960024 2.01 ENST00000370081.2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr6_+_158733692 2.00 ENST00000367094.2
ENST00000367097.3
tubby like protein 4
chr11_-_104817919 1.96 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr11_+_2405833 1.95 ENST00000527343.1
ENST00000464784.2
CD81 molecule
chr2_-_37068530 1.95 ENST00000593798.1
Uncharacterized protein
chr4_+_41937131 1.94 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
transmembrane protein 33
chr8_-_54752406 1.94 ENST00000520188.1
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr9_-_21217310 1.93 ENST00000380216.1
interferon, alpha 16
chr11_+_44117099 1.92 ENST00000533608.1
exostosin glycosyltransferase 2
chr4_+_147096837 1.92 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_-_11685345 1.90 ENST00000430365.2
vestigial like 4 (Drosophila)
chr4_+_69962212 1.87 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr20_-_7921090 1.86 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr1_-_35450897 1.86 ENST00000373337.3
ZMYM6 neighbor
chrX_+_100663243 1.85 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr19_+_54466179 1.84 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr1_-_21377383 1.83 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr4_-_48782259 1.82 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRY-like
chr4_+_69962185 1.82 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chrX_-_119445306 1.82 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
transmembrane protein 255A
chr2_-_70520539 1.80 ENST00000482975.2
ENST00000438261.1
small nuclear ribonucleoprotein polypeptide G
chr17_+_67498538 1.80 ENST00000589647.1
mitogen-activated protein kinase kinase 6
chr11_+_45825616 1.77 ENST00000442528.2
ENST00000456334.1
ENST00000526817.1
solute carrier family 35 (GDP-fucose transporter), member C1
chr5_-_125930929 1.76 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr10_+_51572339 1.75 ENST00000344348.6
nuclear receptor coactivator 4

Network of associatons between targets according to the STRING database.

First level regulatory network of DBX2_HLX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:1901873 regulation of post-translational protein modification(GO:1901873)
2.6 18.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.3 9.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
2.2 6.5 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
2.1 8.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.0 7.9 GO:0031291 Ran protein signal transduction(GO:0031291)
1.9 7.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
1.9 11.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
1.9 3.8 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.9 7.4 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.7 1.7 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.7 5.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.7 6.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
1.6 4.8 GO:2000397 ubiquitin-dependent endocytosis(GO:0070086) regulation of viral budding via host ESCRT complex(GO:1903772) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
1.6 4.8 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.5 4.5 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
1.4 4.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
1.3 4.0 GO:0002188 translation reinitiation(GO:0002188)
1.3 10.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.2 3.5 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
1.1 6.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.0 8.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
1.0 5.9 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
1.0 4.9 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.9 3.8 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.9 3.6 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.9 8.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.9 7.8 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.8 9.3 GO:0001778 plasma membrane repair(GO:0001778)
0.8 1.6 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.8 3.9 GO:0097338 response to clozapine(GO:0097338)
0.8 2.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.8 4.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.7 2.9 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.7 3.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.7 2.1 GO:1901143 insulin catabolic process(GO:1901143)
0.7 4.0 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.6 1.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.6 13.6 GO:0051764 actin crosslink formation(GO:0051764)
0.6 1.9 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.6 2.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.6 6.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.6 1.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.6 1.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.6 5.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.6 1.8 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.6 2.9 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.6 2.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.6 3.3 GO:0032790 ribosome disassembly(GO:0032790)
0.5 3.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.5 1.6 GO:0097052 tryptophan catabolic process to acetyl-CoA(GO:0019442) L-kynurenine metabolic process(GO:0097052)
0.5 2.6 GO:0006574 valine catabolic process(GO:0006574)
0.5 3.6 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.5 12.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.5 1.9 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.5 17.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.5 6.0 GO:0070986 left/right axis specification(GO:0070986)
0.4 3.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 2.2 GO:0097384 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) cellular lipid biosynthetic process(GO:0097384)
0.4 3.5 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.4 1.7 GO:0005997 xylulose metabolic process(GO:0005997)
0.4 1.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.4 4.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 5.8 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.4 6.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.4 1.7 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.4 10.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 5.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.4 3.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.4 4.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.4 2.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.4 3.5 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.4 6.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 3.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.3 2.7 GO:0016139 glycoside catabolic process(GO:0016139)
0.3 11.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.3 0.3 GO:0051180 vitamin transport(GO:0051180)
0.3 9.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 1.0 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3 7.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 7.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 1.5 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.3 4.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.3 4.7 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 12.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 0.8 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.3 3.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 1.1 GO:1903960 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) plasma membrane long-chain fatty acid transport(GO:0015911) negative regulation of anion transmembrane transport(GO:1903960)
0.3 4.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 1.3 GO:0071233 cellular response to leucine(GO:0071233)
0.3 1.8 GO:0042426 choline catabolic process(GO:0042426)
0.2 6.0 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.2 0.7 GO:0006772 thiamine metabolic process(GO:0006772)
0.2 10.5 GO:0015721 bile acid and bile salt transport(GO:0015721) sodium-independent organic anion transport(GO:0043252)
0.2 1.7 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.2 0.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 8.9 GO:0061462 protein localization to lysosome(GO:0061462)
0.2 3.3 GO:0002638 negative regulation of immunoglobulin production(GO:0002638)
0.2 6.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 13.4 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.2 2.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.2 2.5 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.2 0.8 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 1.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 2.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 1.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.2 1.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.7 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 1.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 1.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 1.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 10.6 GO:0008347 glial cell migration(GO:0008347)
0.2 1.0 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.6 GO:2000111 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of macrophage apoptotic process(GO:2000111)
0.2 5.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 1.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 2.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 1.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 9.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 2.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.5 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 2.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.5 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 8.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.8 GO:0008218 bioluminescence(GO:0008218)
0.1 2.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 2.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.8 GO:0090527 actin filament reorganization(GO:0090527)
0.1 4.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 4.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 3.4 GO:0008209 androgen metabolic process(GO:0008209)
0.1 0.5 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 1.4 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:0019321 pentose metabolic process(GO:0019321)
0.1 4.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 2.9 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 0.4 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.1 5.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 6.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 4.5 GO:0051452 intracellular pH reduction(GO:0051452)
0.1 3.6 GO:0061053 somite development(GO:0061053)
0.1 3.9 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 1.3 GO:0033622 integrin activation(GO:0033622)
0.1 0.5 GO:0006063 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585)
0.1 2.0 GO:0061512 protein localization to cilium(GO:0061512)
0.1 0.9 GO:0001501 skeletal system development(GO:0001501)
0.1 0.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.5 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.2 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 7.3 GO:0007498 mesoderm development(GO:0007498)
0.1 1.0 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 9.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 2.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.7 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 2.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.8 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 3.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 4.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.0 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 4.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 1.4 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.7 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0015816 glycine transport(GO:0015816)
0.0 1.5 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 1.9 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 1.0 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 1.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 5.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 3.7 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 3.0 GO:0016573 histone acetylation(GO:0016573)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.9 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 1.6 GO:0006413 translational initiation(GO:0006413)
0.0 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0006953 acute-phase response(GO:0006953)
0.0 1.4 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 2.7 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 1.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.4 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.6 GO:0007566 embryo implantation(GO:0007566)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.4 GO:0044326 dendritic spine neck(GO:0044326)
1.7 6.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
1.6 6.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
1.5 10.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.2 5.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.1 5.6 GO:0044530 supraspliceosomal complex(GO:0044530)
1.1 5.5 GO:0071986 Ragulator complex(GO:0071986)
1.1 12.9 GO:0031595 nuclear proteasome complex(GO:0031595)
1.0 10.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.9 3.8 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.9 4.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.9 4.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.9 5.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.9 3.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.8 6.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.8 4.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.7 2.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.7 3.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.7 4.8 GO:0000813 ESCRT I complex(GO:0000813)
0.7 8.8 GO:0000243 commitment complex(GO:0000243)
0.6 2.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.6 6.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 2.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.5 10.2 GO:0005604 basement membrane(GO:0005604)
0.5 1.9 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.4 3.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.4 4.0 GO:0034464 BBSome(GO:0034464)
0.4 3.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.4 8.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 4.7 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.4 6.1 GO:0030478 actin cap(GO:0030478)
0.4 7.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 2.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 1.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.3 2.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.3 1.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 8.4 GO:0097228 sperm principal piece(GO:0097228)
0.3 1.8 GO:0005683 U7 snRNP(GO:0005683)
0.3 5.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 2.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.3 5.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 5.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 2.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.3 5.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 4.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 6.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 3.5 GO:0044754 autolysosome(GO:0044754)
0.2 7.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 1.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 4.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 1.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 3.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 11.8 GO:0031941 filamentous actin(GO:0031941)
0.2 3.1 GO:0043073 germ cell nucleus(GO:0043073)
0.2 4.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.9 GO:0005688 U6 snRNP(GO:0005688)
0.2 18.1 GO:0005901 caveola(GO:0005901)
0.1 1.2 GO:0070552 BRISC complex(GO:0070552)
0.1 1.7 GO:0043219 lateral loop(GO:0043219)
0.1 4.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 1.7 GO:0005916 fascia adherens(GO:0005916)
0.1 10.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 8.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.3 GO:0071141 SMAD protein complex(GO:0071141)
0.1 5.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.8 GO:0016592 mediator complex(GO:0016592)
0.1 7.4 GO:0005776 autophagosome(GO:0005776)
0.1 1.6 GO:0031932 TORC2 complex(GO:0031932)
0.1 3.0 GO:0005839 proteasome core complex(GO:0005839)
0.1 3.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 2.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 5.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 5.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 11.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 5.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.3 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 6.4 GO:0005643 nuclear pore(GO:0005643)
0.1 5.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146) filopodium tip(GO:0032433)
0.1 2.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 3.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 4.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.3 GO:0005921 gap junction(GO:0005921)
0.0 9.4 GO:0043209 myelin sheath(GO:0043209)
0.0 1.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 4.0 GO:0005840 ribosome(GO:0005840)
0.0 3.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.8 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 10.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 17.9 GO:0005925 focal adhesion(GO:0005925)
0.0 4.0 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0044439 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 1.5 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 10.8 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 14.9 GO:0005730 nucleolus(GO:0005730)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 1.7 GO:0043197 dendritic spine(GO:0043197)
0.0 1.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.5 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 4.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 3.6 GO:0010008 endosome membrane(GO:0010008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
2.1 8.4 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.4 5.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.3 3.8 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.2 10.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.2 9.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.2 12.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.1 6.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.0 10.8 GO:0033038 bitter taste receptor activity(GO:0033038)
1.0 10.6 GO:0046790 virion binding(GO:0046790)
0.9 7.0 GO:0004111 creatine kinase activity(GO:0004111)
0.8 4.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.8 3.8 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.7 3.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.7 2.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.7 6.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.7 3.6 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.7 3.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.7 3.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.7 3.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.7 7.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.7 2.7 GO:0016936 galactoside binding(GO:0016936)
0.6 4.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.6 1.8 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.6 17.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 5.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.6 4.5 GO:0043559 insulin binding(GO:0043559)
0.5 2.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.5 3.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.5 1.5 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.5 1.9 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.5 10.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.5 8.1 GO:0008494 translation activator activity(GO:0008494)
0.5 6.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 16.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 1.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.4 1.6 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4 5.4 GO:0050700 CARD domain binding(GO:0050700)
0.4 2.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.4 5.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 2.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.4 16.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 10.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.4 3.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 3.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 0.9 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.2 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3 1.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 4.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 1.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.3 3.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 0.8 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.3 3.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 3.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 1.3 GO:0070728 leucine binding(GO:0070728)
0.2 0.7 GO:0004802 transketolase activity(GO:0004802)
0.2 2.3 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 6.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 7.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 1.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 6.1 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 14.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 2.3 GO:0015266 protein channel activity(GO:0015266)
0.2 1.7 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 3.1 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 2.9 GO:0043295 glutathione binding(GO:0043295)
0.2 4.4 GO:0008143 poly(A) binding(GO:0008143)
0.2 4.0 GO:0035173 histone kinase activity(GO:0035173)
0.2 0.7 GO:0035473 lipase binding(GO:0035473)
0.2 1.7 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 9.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 2.0 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.2 2.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 2.6 GO:0070513 death domain binding(GO:0070513)
0.2 2.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 1.7 GO:0097016 L27 domain binding(GO:0097016)
0.1 3.0 GO:0070628 proteasome binding(GO:0070628)
0.1 1.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 2.6 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 1.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 6.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 2.6 GO:0004697 protein kinase C activity(GO:0004697)
0.1 2.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 2.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 7.0 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 3.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 3.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 4.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.5 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 4.7 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 4.7 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 4.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.4 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 11.0 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 2.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 1.1 GO:0008201 heparin binding(GO:0008201)
0.1 2.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 1.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.6 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.9 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.6 GO:0051400 BH domain binding(GO:0051400)
0.1 1.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.6 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 19.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 3.7 GO:0032947 protein complex scaffold(GO:0032947)
0.1 1.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 4.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) Notch binding(GO:0005112)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 3.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 12.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 19.2 GO:0003723 RNA binding(GO:0003723)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 14.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 11.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 3.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 13.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 9.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 3.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 1.1 PID EPO PATHWAY EPO signaling pathway
0.3 20.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 13.5 PID BARD1 PATHWAY BARD1 signaling events
0.3 27.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 10.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.2 6.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 11.2 PID AURORA B PATHWAY Aurora B signaling
0.2 3.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 19.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 4.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 3.9 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 7.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 12.9 PID E2F PATHWAY E2F transcription factor network
0.1 4.8 PID ATM PATHWAY ATM pathway
0.1 3.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 5.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 6.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.9 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 4.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 5.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.5 PID INSULIN PATHWAY Insulin Pathway
0.0 1.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 4.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 22.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.7 6.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.6 5.9 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.6 9.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.5 10.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.5 1.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.5 4.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 8.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 5.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 7.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 9.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.4 10.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 4.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.3 3.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 16.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 23.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.3 7.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 1.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 8.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 3.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 12.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 6.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 6.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2 8.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 6.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 1.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 10.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 4.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 9.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 4.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 6.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR