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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for DRGX_PROP1

Z-value: 0.27

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Transcription factors associated with DRGX_PROP1

Gene Symbol Gene ID Gene Info
DRGX
ENSG00000165606.4 dorsal root ganglia homeobox
PROP1
ENSG00000175325.2 PROP paired-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROP1hg19_v2_chr5_-_177423243_1774232430.009.9e-01Click!

Activity profile of DRGX_PROP1 motif

Sorted Z-values of DRGX_PROP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_34204642 6.99 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr16_+_68119247 5.17 ENST00000575270.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr6_-_41039567 5.03 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr4_-_100356291 4.36 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_+_75784850 4.22 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr2_-_55496174 4.18 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
MTIF2
mitochondrial translational initiation factor 2
chr16_+_68119324 3.65 ENST00000349223.5
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr16_+_68119440 3.55 ENST00000346183.3
ENST00000329524.4
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr14_-_75536182 3.54 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr4_+_155484103 3.48 ENST00000302068.4
FGB
fibrinogen beta chain
chr4_-_100356551 2.99 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr22_+_25615489 2.90 ENST00000398215.2
CRYBB2
crystallin, beta B2
chr16_+_24549014 2.75 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr3_-_141747950 2.73 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_+_155484155 2.65 ENST00000509493.1
FGB
fibrinogen beta chain
chr17_-_39023462 2.60 ENST00000251643.4
KRT12
keratin 12
chr8_+_26150628 2.56 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_+_50569575 2.56 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr5_-_134735568 2.48 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr15_+_66874502 2.41 ENST00000558797.1
RP11-321F6.1
HCG2003567; Uncharacterized protein
chr4_+_40198527 2.39 ENST00000381799.5
RHOH
ras homolog family member H
chr3_+_138340067 2.36 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chrX_+_119737806 2.35 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr16_-_67517716 2.27 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr10_+_97803151 2.26 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ
cyclin J
chr2_-_17981462 2.24 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr4_+_113568207 2.15 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr3_-_197300194 2.09 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr3_-_157824292 2.09 ENST00000483851.2
SHOX2
short stature homeobox 2
chr9_+_42671887 2.07 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr9_-_70465758 2.01 ENST00000489273.1
CBWD5
COBW domain containing 5
chr17_-_56082455 1.80 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr3_+_138340049 1.76 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr3_+_149192475 1.75 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr16_-_69373396 1.75 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr5_+_140571902 1.73 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr5_-_111093759 1.70 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr14_+_22985251 1.70 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr2_+_75873902 1.69 ENST00000393909.2
ENST00000358788.6
ENST00000409374.1
MRPL19
mitochondrial ribosomal protein L19
chr7_-_25268104 1.67 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr2_+_191334212 1.64 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr6_-_150067696 1.60 ENST00000340413.2
ENST00000367403.3
NUP43
nucleoporin 43kDa
chr5_-_111312622 1.58 ENST00000395634.3
NREP
neuronal regeneration related protein
chr17_+_44588877 1.57 ENST00000576629.1
LRRC37A2
leucine rich repeat containing 37, member A2
chr17_-_29641104 1.53 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr4_+_69313145 1.50 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr8_-_57123815 1.47 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr4_-_143227088 1.46 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr17_+_71228537 1.46 ENST00000577615.1
ENST00000585109.1
C17orf80
chromosome 17 open reading frame 80
chr17_+_74463650 1.45 ENST00000392492.3
AANAT
aralkylamine N-acetyltransferase
chr12_-_118797475 1.43 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr10_-_75226166 1.39 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr17_+_71228793 1.37 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr12_+_59989918 1.37 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr9_+_77230499 1.34 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr2_-_70529180 1.33 ENST00000450256.1
ENST00000037869.3
FAM136A
family with sequence similarity 136, member A
chr1_+_206557366 1.31 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr6_-_32908792 1.31 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr4_+_68424434 1.30 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr1_+_62439037 1.29 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr12_-_47219733 1.28 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4
solute carrier family 38, member 4
chr17_-_29641084 1.28 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr3_-_87325612 1.28 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU1F1
POU class 1 homeobox 1
chr6_-_32908765 1.24 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr13_+_53602894 1.23 ENST00000219022.2
OLFM4
olfactomedin 4
chr2_+_162272605 1.21 ENST00000389554.3
TBR1
T-box, brain, 1
chr12_-_118628350 1.20 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr17_+_71228740 1.20 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr18_+_616711 1.19 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr2_+_86669118 1.16 ENST00000427678.1
ENST00000542128.1
KDM3A
lysine (K)-specific demethylase 3A
chr5_-_111091948 1.10 ENST00000447165.2
NREP
neuronal regeneration related protein
chr3_-_18480260 1.10 ENST00000454909.2
SATB1
SATB homeobox 1
chr15_+_57511609 1.09 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chrX_+_108779004 1.07 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr16_-_74700737 1.07 ENST00000576652.1
ENST00000572337.1
ENST00000571750.1
ENST00000572990.1
ENST00000361070.4
RFWD3
ring finger and WD repeat domain 3
chr20_-_34330129 1.04 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RBM39
RNA binding motif protein 39
chr2_+_102413726 1.02 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr7_+_93535866 1.00 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr3_-_87325728 1.00 ENST00000350375.2
POU1F1
POU class 1 homeobox 1
chrX_+_78200913 0.99 ENST00000171757.2
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr5_+_137203557 0.99 ENST00000515645.1
MYOT
myotilin
chr1_+_3773825 0.97 ENST00000378209.3
ENST00000338895.3
ENST00000378212.2
ENST00000341385.3
DFFB
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr15_-_55541227 0.95 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr6_-_111804905 0.92 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr1_-_21377383 0.92 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chrX_+_77166172 0.90 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr16_+_1728257 0.89 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L
hematological and neurological expressed 1-like
chr2_-_172087824 0.85 ENST00000521943.1
TLK1
tousled-like kinase 1
chr7_+_93535817 0.85 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr5_-_66492562 0.84 ENST00000256447.4
CD180
CD180 molecule
chrX_+_78200829 0.84 ENST00000544091.1
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr2_+_185463093 0.84 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr4_-_143226979 0.80 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_-_17752912 0.79 ENST00000398054.1
ENST00000381840.2
FGL1
fibrinogen-like 1
chrX_-_138724994 0.78 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr2_-_58468437 0.77 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chr8_-_17752996 0.77 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr5_+_137203541 0.75 ENST00000421631.2
MYOT
myotilin
chr1_+_74701062 0.75 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr1_+_244214577 0.73 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr12_-_10959892 0.71 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr13_-_95131923 0.70 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr7_-_115608304 0.69 ENST00000457268.1
TFEC
transcription factor EC
chr1_-_186430222 0.68 ENST00000391997.2
PDC
phosducin
chr12_-_110883346 0.68 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr15_+_75628232 0.67 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chr14_-_101295407 0.67 ENST00000596284.1
AL117190.2
AL117190.2
chr1_+_158323755 0.67 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
CD1E
CD1e molecule
chr8_-_86253888 0.67 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr15_+_75628394 0.66 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr12_+_100897130 0.66 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr5_+_59783941 0.65 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr6_+_27791862 0.63 ENST00000355057.1
HIST1H4J
histone cluster 1, H4j
chr11_+_18433840 0.63 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr7_+_136553370 0.62 ENST00000445907.2
CHRM2
cholinergic receptor, muscarinic 2
chr9_+_2159850 0.62 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_21440440 0.61 ENST00000276927.1
IFNA1
interferon, alpha 1
chr4_+_88571429 0.60 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr22_-_29107919 0.58 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr4_+_142558078 0.55 ENST00000529613.1
IL15
interleukin 15
chr11_+_49050504 0.55 ENST00000332682.7
TRIM49B
tripartite motif containing 49B
chr15_+_44092784 0.55 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr10_+_115312766 0.55 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr7_-_122840015 0.53 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr1_+_174933899 0.51 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr6_+_42896865 0.49 ENST00000372836.4
ENST00000394142.3
CNPY3
canopy FGF signaling regulator 3
chr18_-_31628558 0.48 ENST00000535384.1
NOL4
nucleolar protein 4
chr18_+_616672 0.47 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chrX_+_11311533 0.47 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
AMELX
amelogenin, X-linked
chr12_-_43833515 0.46 ENST00000549670.1
ENST00000395541.2
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr17_+_39240459 0.44 ENST00000391417.4
KRTAP4-7
keratin associated protein 4-7
chr11_-_102576537 0.44 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr9_+_136501478 0.44 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr3_-_45838011 0.44 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr8_-_30706608 0.43 ENST00000256246.2
TEX15
testis expressed 15
chr14_-_21567009 0.43 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr10_+_106034884 0.42 ENST00000369707.2
ENST00000429569.2
GSTO2
glutathione S-transferase omega 2
chr19_+_13842559 0.41 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr5_+_140514782 0.40 ENST00000231134.5
PCDHB5
protocadherin beta 5
chrY_-_6742068 0.39 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr3_-_3151664 0.39 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
IL5RA
interleukin 5 receptor, alpha
chr17_-_39623681 0.37 ENST00000225899.3
KRT32
keratin 32
chr1_-_169703203 0.37 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr3_-_165555200 0.36 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr3_-_32544900 0.33 ENST00000205636.3
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr16_+_69373323 0.33 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr20_+_32150140 0.33 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr10_+_18689637 0.33 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr3_+_149191723 0.32 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr11_-_8964580 0.31 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr1_+_84630645 0.31 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr18_-_19994830 0.30 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr5_-_59783882 0.30 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_+_68835911 0.30 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr1_-_241799232 0.28 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr5_-_11588907 0.28 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr8_-_125577940 0.24 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr2_+_196313239 0.23 ENST00000413290.1
AC064834.1
AC064834.1
chr10_-_102989551 0.23 ENST00000370193.2
LBX1
ladybird homeobox 1
chr5_-_9630463 0.23 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr4_+_160188889 0.22 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr17_+_41150290 0.20 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr11_+_113779704 0.19 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr5_+_137203465 0.19 ENST00000239926.4
MYOT
myotilin
chr8_-_6420930 0.19 ENST00000325203.5
ANGPT2
angiopoietin 2
chr3_-_45837959 0.18 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr3_-_33686743 0.18 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr12_+_122688090 0.18 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr4_-_76957214 0.18 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr8_-_93107696 0.18 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_18725758 0.17 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr11_-_71955210 0.17 ENST00000298231.5
PHOX2A
paired-like homeobox 2a
chr2_-_89160770 0.17 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chrX_+_107288197 0.16 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr5_+_169931009 0.15 ENST00000328939.4
ENST00000390656.4
KCNIP1
Kv channel interacting protein 1
chr3_+_39371191 0.15 ENST00000326306.4
CCR8
chemokine (C-C motif) receptor 8
chr19_+_54619125 0.15 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
PRPF31
pre-mRNA processing factor 31
chr3_-_151034734 0.15 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr16_+_89334512 0.14 ENST00000602042.1
AC137932.1
AC137932.1
chr2_-_145278475 0.14 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr5_+_140207536 0.14 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr5_+_142149955 0.13 ENST00000378004.3
ARHGAP26
Rho GTPase activating protein 26
chr5_+_142149932 0.12 ENST00000274498.4
ARHGAP26
Rho GTPase activating protein 26
chr6_+_30130969 0.12 ENST00000376694.4
TRIM15
tripartite motif containing 15
chr11_-_89540388 0.10 ENST00000532501.2
TRIM49
tripartite motif containing 49
chr4_+_76649797 0.10 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr6_-_27835357 0.10 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr1_+_225600404 0.09 ENST00000366845.2
AC092811.1
AC092811.1
chr7_+_152456829 0.08 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr9_-_27005686 0.08 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr17_+_3118915 0.08 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr2_-_208994548 0.08 ENST00000282141.3
CRYGC
crystallin, gamma C
chr12_-_10324716 0.08 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr14_-_36988882 0.08 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr16_-_21663950 0.07 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr7_+_107224364 0.05 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr6_+_72926145 0.05 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_115572415 0.05 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr3_-_167191814 0.05 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr14_+_75536280 0.04 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C

Network of associatons between targets according to the STRING database.

First level regulatory network of DRGX_PROP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.7 7.0 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.8 2.5 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.8 2.5 GO:1901837 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.8 6.5 GO:0032790 ribosome disassembly(GO:0032790)
0.6 6.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 2.3 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.5 12.4 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.5 1.4 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.5 2.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.4 1.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.4 2.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.4 1.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.3 0.9 GO:0071284 cellular response to lead ion(GO:0071284)
0.2 2.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.2 1.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.2 0.7 GO:2001250 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 1.2 GO:0021764 amygdala development(GO:0021764)
0.2 0.6 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 2.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 0.6 GO:0045062 extrathymic T cell selection(GO:0045062)
0.2 1.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.2 1.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 0.7 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 0.8 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.2 1.7 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.2 0.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 2.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.1 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.3 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1 0.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 1.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.6 GO:0019249 lactate biosynthetic process(GO:0019249)
0.1 0.7 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 2.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.6 GO:0015824 proline transport(GO:0015824)
0.1 1.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252) prostate gland growth(GO:0060736)
0.1 0.3 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 1.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 1.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.4 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.3 GO:0097338 response to clozapine(GO:0097338)
0.1 2.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.4 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 2.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:0021558 trochlear nerve development(GO:0021558)
0.1 2.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.7 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.5 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 2.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 2.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 1.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.7 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 1.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0034505 tooth mineralization(GO:0034505)
0.0 5.6 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 1.7 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 2.5 GO:0006275 regulation of DNA replication(GO:0006275)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 7.7 GO:0005577 fibrinogen complex(GO:0005577)
0.6 2.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 2.5 GO:0001740 Barr body(GO:0001740)
0.2 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.7 GO:0017119 Golgi transport complex(GO:0017119)
0.1 2.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.3 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 2.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.1 GO:0098576 lumenal side of membrane(GO:0098576)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 0.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 3.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.2 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.3 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.7 2.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.6 3.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.5 7.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.5 2.3 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.4 1.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.3 1.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 0.9 GO:0032767 copper-dependent protein binding(GO:0032767)
0.3 4.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 2.5 GO:0000182 rDNA binding(GO:0000182)
0.2 0.7 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 1.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 0.5 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 2.6 GO:0048156 tau protein binding(GO:0048156)
0.1 0.4 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 1.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.7 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 2.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 2.0 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.6 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.7 GO:0004064 arylesterase activity(GO:0004064)
0.1 2.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 1.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.4 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.4 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 2.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.7 GO:0031013 troponin I binding(GO:0031013)
0.1 5.0 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.7 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 6.1 GO:0051087 chaperone binding(GO:0051087)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 3.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.9 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 10.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 3.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.0 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.8 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 6.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 7.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 4.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 3.3 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 3.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.8 7.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.4 6.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 2.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 2.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling