GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
E2F2 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000007968.6	E2F transcription factor 2
E2F5 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000133740.6	E2F transcription factor 5

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2F2	hg19_v2_chr1_-_23857698_23857733	-0.46	8.6e-13	Click!
E2F5	hg19_v2_chr8_+_86099884_86099920	0.41	3.2e-10	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr15_-_64673630 Show fit	156.03	ENST00000558008.1 ENST00000559519.1 ENST00000380258.2	KIAA0101 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0101
chr2_+_10262857 Show fit	152.65	ENST00000304567.5	RRM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonucleotide reductase M2
chr2_-_136633940 Show fit	143.42	ENST00000264156.2	MCM6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 6
chr10_+_62538089 Show fit	141.94	ENST00000519078.2 ENST00000395284.3 ENST00000316629.4	CDK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 1
chr10_+_62538248 Show fit	127.75	ENST00000448257.2	CDK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 1
chr8_-_124408652 Show fit	118.04	ENST00000287394.5	ATAD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase family, AAA domain containing 2
chr6_+_24775153 Show fit	110.76	ENST00000356509.3 ENST00000230056.3	GMNN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	geminin, DNA replication inhibitor
chr6_-_52149475 Show fit	109.35	ENST00000419835.2 ENST00000229854.7 ENST00000596288.1	MCM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 3
chr3_+_127317066 Show fit	105.24	ENST00000265056.7	MCM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 2
chr20_+_25388293 Show fit	104.83	ENST00000262460.4 ENST00000429262.2	GINS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GINS complex subunit 1 (Psf1 homolog)
chr19_-_10305752 Show fit	102.39	ENST00000540357.1 ENST00000359526.4 ENST00000340748.4	DNMT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DNA (cytosine-5-)-methyltransferase 1
chr7_-_99699538 Show fit	85.19	ENST00000343023.6 ENST00000303887.5	MCM7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 7
chr7_+_26241310 Show fit	84.59	ENST00000396386.2	CBX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 3
chr7_+_26241325 Show fit	83.12	ENST00000456948.1 ENST00000409747.1	CBX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 3
chr15_-_64673665 Show fit	71.84	ENST00000300035.4	KIAA0101 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0101
chr5_-_79950371 Show fit	63.57	ENST00000511032.1 ENST00000504396.1 ENST00000505337.1	DHFR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dihydrofolate reductase
chr1_-_26232951 Show fit	60.40	ENST00000426559.2 ENST00000455785.2	STMN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stathmin 1
chr18_+_19192228 Show fit	59.84	ENST00000300413.5 ENST00000579618.1 ENST00000582475.1	SNRPD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr6_-_17706618 Show fit	57.72	ENST00000262077.2 ENST00000537253.1	NUP153 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 153kDa
chr5_-_79950775 Show fit	57.08	ENST00000439211.2	DHFR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dihydrofolate reductase
chr22_+_35796108 Show fit	56.60	ENST00000382011.5 ENST00000416905.1	MCM5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 5
chr7_-_148581251 Show fit	53.64	ENST00000478654.1 ENST00000460911.1 ENST00000350995.2	EZH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enhancer of zeste homolog 2 (Drosophila)
chr13_+_114238997 Show fit	51.95	ENST00000538138.1 ENST00000375370.5	TFDP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor Dp-1
chr1_+_212208919 Show fit	51.89	ENST00000366991.4 ENST00000542077.1	DTL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr15_-_66649010 Show fit	51.47	ENST00000367709.4 ENST00000261881.4	TIPIN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TIMELESS interacting protein
chr1_-_26232522 Show fit	51.02	ENST00000399728.1	STMN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stathmin 1
chr22_+_35796056 Show fit	50.66	ENST00000216122.4	MCM5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 5
chr7_-_148581360 Show fit	50.24	ENST00000320356.2 ENST00000541220.1 ENST00000483967.1 ENST00000536783.1	EZH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enhancer of zeste homolog 2 (Drosophila)
chr2_+_232573222 Show fit	49.18	ENST00000341369.7 ENST00000409683.1	PTMA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prothymosin, alpha
chr10_+_112327425 Show fit	48.63	ENST00000361804.4	SMC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 3
chr7_-_158497431 Show fit	48.28	ENST00000449727.2 ENST00000409339.3 ENST00000409423.1 ENST00000356309.3	NCAPG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	non-SMC condensin II complex, subunit G2
chr14_-_50154921 Show fit	46.65	ENST00000553805.2 ENST00000554396.1 ENST00000216367.5 ENST00000539565.2	POLE2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (DNA directed), epsilon 2, accessory subunit
chr14_+_51706886 Show fit	46.53	ENST00000457354.2	TMX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin-related transmembrane protein 1
chrX_+_123095546 Show fit	46.29	ENST00000371157.3 ENST00000371145.3 ENST00000371144.3	STAG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stromal antigen 2
chr2_-_47168850 Show fit	46.00	ENST00000409207.1	MCFD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	multiple coagulation factor deficiency 2
chr3_+_44803209 Show fit	45.40	ENST00000326047.4	KIF15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kinesin family member 15
chr14_-_69864993 Show fit	44.78	ENST00000555373.1	ERH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enhancer of rudimentary homolog (Drosophila)
chr5_+_36152091 Show fit	44.04	ENST00000274254.5	SKP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr4_-_174256276 Show fit	42.76	ENST00000296503.5	HMGB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group box 2
chr2_+_48010312 Show fit	41.80	ENST00000540021.1	MSH6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mutS homolog 6
chr10_-_58120996 Show fit	41.47	ENST00000361148.6 ENST00000395405.1 ENST00000373944.3	ZWINT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ZW10 interacting kinetochore protein
chr20_-_32274179 Show fit	40.36	ENST00000343380.5	E2F1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	E2F transcription factor 1
chr2_+_48010221 Show fit	39.78	ENST00000234420.5	MSH6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mutS homolog 6
chr9_-_35080013 Show fit	37.41	ENST00000378643.3	FANCG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Fanconi anemia, complementation group G
chr11_+_64808368 Show fit	36.54	ENST00000531072.1 ENST00000398846.1	SAC3D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SAC3 domain containing 1
chr7_-_94285511 Show fit	36.30	ENST00000265735.7	SGCE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sarcoglycan, epsilon
chr6_+_24775641 Show fit	36.29	ENST00000378054.2 ENST00000476555.1	GMNN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	geminin, DNA replication inhibitor
chr7_-_94285472 Show fit	35.61	ENST00000437425.2 ENST00000447873.1 ENST00000415788.2	SGCE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sarcoglycan, epsilon
chr5_+_36152163 Show fit	35.42	ENST00000274255.6	SKP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr11_+_125495862 Show fit	35.21	ENST00000428830.2 ENST00000544373.1 ENST00000527013.1 ENST00000526937.1 ENST00000534685.1	CHEK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	checkpoint kinase 1
chr19_+_36705504 Show fit	35.13	ENST00000456324.1	ZNF146 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 146
chr10_+_13203543 Show fit	34.58	ENST00000378714.3 ENST00000479669.1 ENST00000484800.2	MCM10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 10
chr8_+_128748308 Show fit	34.47	ENST00000377970.2	MYC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	v-myc avian myelocytomatosis viral oncogene homolog
chr11_+_4116054 Show fit	34.33	ENST00000423050.2	RRM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonucleotide reductase M1
chr16_-_3030407 Show fit	34.02	ENST00000431515.2 ENST00000574385.1 ENST00000576268.1 ENST00000574730.1 ENST00000575632.1 ENST00000573944.1 ENST00000262300.8	PKMYT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase, membrane associated tyrosine/threonine 1
chr2_+_232573208 Show fit	33.52	ENST00000409115.3	PTMA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prothymosin, alpha
chr11_+_64808675 Show fit	33.35	ENST00000529996.1	SAC3D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SAC3 domain containing 1
chr7_+_26240776 Show fit	32.76	ENST00000337620.4	CBX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 3
chr22_+_35653445 Show fit	32.55	ENST00000420166.1 ENST00000444518.2 ENST00000455359.1 ENST00000216106.5	HMGXB4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HMG box domain containing 4
chr2_-_47168906 Show fit	32.09	ENST00000444761.2 ENST00000409147.1	MCFD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	multiple coagulation factor deficiency 2
chr19_+_36706024 Show fit	31.98	ENST00000443387.2	ZNF146 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 146
chr22_+_20105259 Show fit	31.24	ENST00000416427.1 ENST00000421656.1 ENST00000423859.1 ENST00000418705.2	RANBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAN binding protein 1
chr16_-_3030283 Show fit	31.04	ENST00000572619.1 ENST00000574415.1 ENST00000440027.2 ENST00000572059.1	PKMYT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase, membrane associated tyrosine/threonine 1
chr7_-_94285402 Show fit	30.83	ENST00000428696.2 ENST00000445866.2	SGCE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sarcoglycan, epsilon
chr16_-_85722530 Show fit	30.48	ENST00000253462.3	GINS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GINS complex subunit 2 (Psf2 homolog)
chr1_-_26233423 Show fit	29.67	ENST00000357865.2	STMN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stathmin 1
chr3_-_133380731 Show fit	29.49	ENST00000260810.5	TOPBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	topoisomerase (DNA) II binding protein 1
chrX_+_106871713 Show fit	29.42	ENST00000372435.4 ENST00000372428.4 ENST00000372419.3 ENST00000543248.1	PRPS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoribosyl pyrophosphate synthetase 1
chr17_-_17184605 Show fit	28.62	ENST00000268717.5	COPS3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COP9 signalosome subunit 3
chr17_+_30264014 Show fit	27.64	ENST00000322652.5 ENST00000580398.1	SUZ12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SUZ12 polycomb repressive complex 2 subunit
chr22_+_20105012 Show fit	27.64	ENST00000331821.3 ENST00000411892.1	RANBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAN binding protein 1
chr1_-_222885770 Show fit	27.53	ENST00000355727.2 ENST00000340020.6	AIDA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	axin interactor, dorsalization associated
chr7_+_94285637 Show fit	27.21	ENST00000482108.1 ENST00000488574.1	PEG10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paternally expressed 10
chr12_-_31479045 Show fit	26.72	ENST00000539409.1 ENST00000395766.1	FAM60A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 60, member A
chrX_+_118708517 Show fit	24.85	ENST00000346330.3	UBE2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2A
chr7_+_120591170 Show fit	24.83	ENST00000431467.1	ING3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inhibitor of growth family, member 3
chr20_-_5100591 Show fit	24.69	ENST00000379143.5	PCNA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proliferating cell nuclear antigen
chr12_+_109535923 Show fit	24.54	ENST00000336865.2	UNG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	uracil-DNA glycosylase
chr6_+_135502466 Show fit	23.87	ENST00000367814.4	MYB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	v-myb avian myeloblastosis viral oncogene homolog
chr8_+_128748466 Show fit	23.36	ENST00000524013.1 ENST00000520751.1	MYC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	v-myc avian myelocytomatosis viral oncogene homolog
chrX_+_21958814 Show fit	23.29	ENST00000379404.1 ENST00000415881.2	SMS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermine synthase
chr1_-_205719295 Show fit	23.22	ENST00000367142.4	NUCKS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr7_+_139044621 Show fit	23.19	ENST00000354926.4	C7orf55-LUC7L2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	C7orf55-LUC7L2 readthrough
chr17_-_56084578 Show fit	23.12	ENST00000582730.2 ENST00000584773.1 ENST00000585096.1 ENST00000258962.4	SRSF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 1
chr14_+_35452104 Show fit	23.03	ENST00000216774.6 ENST00000546080.1	SRP54 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal recognition particle 54kDa
chrX_+_21958674 Show fit	22.82	ENST00000404933.2	SMS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermine synthase
chr6_-_27114577 Show fit	22.66	ENST00000356950.1 ENST00000396891.4	HIST1H2BK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histone cluster 1, H2bk
chr9_+_106856831 Show fit	22.55	ENST00000303219.8 ENST00000374787.3	SMC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 2
chr6_+_135502408 Show fit	22.20	ENST00000341911.5 ENST00000442647.2 ENST00000316528.8	MYB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	v-myb avian myeloblastosis viral oncogene homolog
chr10_-_13390021 Show fit	22.01	ENST00000537130.1	SEPHS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	selenophosphate synthetase 1
chr11_+_47236489 Show fit	22.01	ENST00000256996.4 ENST00000378603.3 ENST00000378600.3 ENST00000378601.3	DDB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	damage-specific DNA binding protein 2, 48kDa
chrX_+_118708493 Show fit	21.40	ENST00000371558.2	UBE2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2A
chrX_-_53449593 Show fit	20.94	ENST00000375340.6 ENST00000322213.4	SMC1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 1A
chr11_+_9406169 Show fit	20.90	ENST00000379719.3 ENST00000527431.1	IPO7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	importin 7
chr14_+_35452169 Show fit	20.85	ENST00000555557.1	SRP54 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal recognition particle 54kDa
chr11_-_19263145 Show fit	20.78	ENST00000532666.1 ENST00000527884.1	E2F8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	E2F transcription factor 8
chr4_+_71859156 Show fit	20.57	ENST00000286648.5 ENST00000504730.1 ENST00000504952.1	DCK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	deoxycytidine kinase
chr8_+_48873453 Show fit	20.12	ENST00000523944.1	MCM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 4
chr8_+_48873479 Show fit	19.34	ENST00000262105.2	MCM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 4
chr11_-_118966167 Show fit	19.10	ENST00000530167.1	H2AFX Links Ensembl NCBI GeneCards UniProt NextProt Show fit	H2A histone family, member X
chrX_+_24711997 Show fit	19.04	ENST00000379068.3 ENST00000379059.3	POLA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (DNA directed), alpha 1, catalytic subunit
chr2_-_38978492 Show fit	18.25	ENST00000409276.1 ENST00000446327.2 ENST00000313117.6	SRSF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 7
chr3_+_52719936 Show fit	18.19	ENST00000418458.1 ENST00000394799.2	GNL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein-like 3 (nucleolar)
chr16_-_12009833 Show fit	17.92	ENST00000420576.2	GSPT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G1 to S phase transition 1
chr19_+_16187085 Show fit	17.86	ENST00000300933.4	TPM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tropomyosin 4
chr4_+_129730779 Show fit	17.76	ENST00000226319.6	PHF17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	jade family PHD finger 1
chr4_+_129730947 Show fit	17.61	ENST00000452328.2 ENST00000504089.1	PHF17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	jade family PHD finger 1
chr3_-_141868293 Show fit	17.46	ENST00000317104.7 ENST00000494358.1	TFDP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_203103281 Show fit	17.41	ENST00000392244.3 ENST00000409181.1 ENST00000409712.1 ENST00000409498.2 ENST00000409368.1 ENST00000392245.1 ENST00000392246.2	SUMO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 1
chr16_-_23607598 Show fit	17.32	ENST00000562133.1 ENST00000570319.1 ENST00000007516.3	NDUFAB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr4_-_170679024 Show fit	17.30	ENST00000393381.2	C4orf27 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 4 open reading frame 27
chr7_-_44887620 Show fit	17.29	ENST00000349299.3 ENST00000521529.1 ENST00000308153.4 ENST00000350771.3 ENST00000222690.6 ENST00000381124.5 ENST00000437072.1 ENST00000446531.1	H2AFV Links Ensembl NCBI GeneCards UniProt NextProt Show fit	H2A histone family, member V
chr12_+_57623869 Show fit	16.82	ENST00000414700.3 ENST00000557703.1	SHMT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 2 (mitochondrial)
chr7_+_120590803 Show fit	16.49	ENST00000315870.5 ENST00000339121.5 ENST00000445699.1	ING3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inhibitor of growth family, member 3
chr1_-_28241226 Show fit	16.31	ENST00000373912.3 ENST00000373909.3	RPA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	replication protein A2, 32kDa
chr5_+_43121698 Show fit	16.29	ENST00000505606.2 ENST00000509634.1 ENST00000509341.1	ZNF131 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 131
chr16_+_29817399 Show fit	16.12	ENST00000545521.1	MAZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_+_47630108 Show fit	16.09	ENST00000233146.2 ENST00000454849.1 ENST00000543555.1	MSH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mutS homolog 2
chr7_+_6048856 Show fit	15.99	ENST00000223029.3 ENST00000400479.2 ENST00000395236.2	AIMP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chrX_+_131157322 Show fit	15.69	ENST00000481105.1 ENST00000354719.6 ENST00000394335.2	MST4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Serine/threonine-protein kinase MST4
chr5_+_140019079 Show fit	15.51	ENST00000252100.6	TMCO6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane and coiled-coil domains 6
chrX_+_131157290 Show fit	15.47	ENST00000394334.2	MST4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Serine/threonine-protein kinase MST4
chr3_+_14219858 Show fit	15.41	ENST00000306024.3	LSM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_+_75348592 Show fit	14.96	ENST00000334220.4	DLST Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr1_+_33116743 Show fit	14.93	ENST00000414241.3 ENST00000373493.5	RBBP4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoblastoma binding protein 4
chr9_+_86595626 Show fit	14.76	ENST00000445877.1 ENST00000325875.3	RMI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RecQ mediated genome instability 1
chr2_-_27632390 Show fit	14.76	ENST00000350803.4 ENST00000344034.4	PPM1G Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr5_+_43121607 Show fit	14.39	ENST00000509156.1 ENST00000508259.1 ENST00000306938.4 ENST00000399534.1	ZNF131 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 131
chr12_+_57623477 Show fit	14.28	ENST00000557487.1 ENST00000555634.1 ENST00000556689.1	SHMT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 2 (mitochondrial)
chr6_-_5260963 Show fit	14.13	ENST00000464010.1 ENST00000468929.1 ENST00000480566.1	LYRM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LYR motif containing 4
chr5_+_138629389 Show fit	13.98	ENST00000504045.1 ENST00000504311.1 ENST00000502499.1	MATR3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	matrin 3
chr1_-_24306835 Show fit	13.82	ENST00000484146.2	SRSF10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 10
chr6_+_31633011 Show fit	13.52	ENST00000375885.4	CSNK2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	casein kinase 2, beta polypeptide
chr19_+_10765699 Show fit	13.45	ENST00000590009.1	ILF3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin enhancer binding factor 3, 90kDa
chr3_-_185655795 Show fit	13.25	ENST00000342294.4 ENST00000382191.4 ENST00000453386.2	TRA2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transformer 2 beta homolog (Drosophila)
chr5_+_138629417 Show fit	13.20	ENST00000510056.1 ENST00000511249.1 ENST00000503811.1 ENST00000511378.1	MATR3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	matrin 3
chr5_+_138629337 Show fit	13.18	ENST00000394805.3 ENST00000512876.1 ENST00000513678.1	MATR3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	matrin 3
chr9_+_106856541 Show fit	13.12	ENST00000286398.7 ENST00000440179.1 ENST00000374793.3	SMC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 2
chr11_+_74303575 Show fit	13.09	ENST00000263681.2	POLD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (DNA-directed), delta 3, accessory subunit
chr3_-_10028366 Show fit	12.52	ENST00000429759.1	EMC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ER membrane protein complex subunit 3
chr19_-_50432782 Show fit	12.33	ENST00000413454.1 ENST00000596437.1 ENST00000341114.3 ENST00000595948.1	NUP62 Links Ensembl NCBI GeneCards UniProt NextProt Show fit IL4I1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 62kDa interleukin 4 induced 1
chr14_+_64854958 Show fit	12.26	ENST00000555709.2 ENST00000554739.1 ENST00000554768.1 ENST00000216605.8	MTHFD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr16_+_67596310 Show fit	12.11	ENST00000264010.4 ENST00000401394.1	CTCF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CCCTC-binding factor (zinc finger protein)
chr8_-_120868078 Show fit	12.06	ENST00000313655.4	DSCC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DNA replication and sister chromatid cohesion 1
chr10_-_13390270 Show fit	11.85	ENST00000378614.4 ENST00000545675.1 ENST00000327347.5	SEPHS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	selenophosphate synthetase 1
chrX_-_106243451 Show fit	11.82	ENST00000355610.4 ENST00000535534.1	MORC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MORC family CW-type zinc finger 4
chr17_+_3572087 Show fit	11.80	ENST00000248378.5 ENST00000397133.2	EMC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ER membrane protein complex subunit 6
chr5_+_140019004 Show fit	11.66	ENST00000394671.3 ENST00000511410.1 ENST00000537378.1	TMCO6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane and coiled-coil domains 6
chr16_+_28962128 Show fit	11.59	ENST00000564978.1 ENST00000320805.4	NFATC2IP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr6_+_88299833 Show fit	11.06	ENST00000392844.3 ENST00000257789.4 ENST00000546266.1 ENST00000417380.2	ORC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	origin recognition complex, subunit 3
chr1_-_54303934 Show fit	10.96	ENST00000537333.1	NDC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDC1 transmembrane nucleoporin
chr12_+_122326662 Show fit	10.54	ENST00000261817.2 ENST00000538613.1 ENST00000542602.1	PSMD9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr1_-_23670813 Show fit	10.23	ENST00000374612.1	HNRNPR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein R
chr6_-_160210604 Show fit	9.95	ENST00000420894.2 ENST00000539756.1 ENST00000544255.1	TCP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	t-complex 1
chr10_+_73724123 Show fit	9.86	ENST00000373115.4	CHST3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	carbohydrate (chondroitin 6) sulfotransferase 3
chr8_-_67525473 Show fit	9.80	ENST00000522677.3	MYBL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	v-myb avian myeloblastosis viral oncogene homolog-like 1
chr1_-_23670817 Show fit	9.79	ENST00000478691.1	HNRNPR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein R
chr17_-_57184064 Show fit	9.77	ENST00000262294.7	TRIM37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 37
chr17_-_74733404 Show fit	9.72	ENST00000508921.3 ENST00000583836.1 ENST00000358156.6 ENST00000392485.2 ENST00000359995.5	SRSF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 2
chr2_-_174830430 Show fit	9.68	ENST00000310015.6 ENST00000455789.2	SP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Sp3 transcription factor
chr6_+_30312908 Show fit	9.67	ENST00000433076.2 ENST00000442966.2 ENST00000428040.2 ENST00000436442.2	RPP21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonuclease P/MRP 21kDa subunit
chr12_+_122326630 Show fit	9.60	ENST00000541212.1 ENST00000340175.5	PSMD9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr17_-_57184260 Show fit	9.21	ENST00000376149.3 ENST00000393066.3	TRIM37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 37
chr17_-_73781567 Show fit	9.14	ENST00000586607.1	H3F3B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	H3 histone, family 3B (H3.3B)
chrX_+_70752917 Show fit	9.09	ENST00000373719.3	OGT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	O-linked N-acetylglucosamine (GlcNAc) transferase
chr14_-_68141535 Show fit	9.03	ENST00000554659.1	VTI1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vesicle transport through interaction with t-SNAREs 1B
chr11_-_64546202 Show fit	8.90	ENST00000377390.3 ENST00000227503.9 ENST00000377394.3 ENST00000422298.2 ENST00000334944.5	SF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	splicing factor 1
chr22_-_29137771 Show fit	8.73	ENST00000439200.1 ENST00000405598.1 ENST00000398017.2 ENST00000425190.2 ENST00000348295.3 ENST00000382578.1 ENST00000382565.1 ENST00000382566.1 ENST00000382580.2 ENST00000328354.6	CHEK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	checkpoint kinase 2
chr3_+_41240925 Show fit	8.72	ENST00000396183.3 ENST00000349496.5 ENST00000453024.1	CTNNB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	catenin (cadherin-associated protein), beta 1, 88kDa
chr2_-_100106419 Show fit	8.55	ENST00000393445.3 ENST00000258428.3	REV1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	REV1, polymerase (DNA directed)
chr3_-_141868357 Show fit	8.54	ENST00000489671.1 ENST00000475734.1 ENST00000467072.1 ENST00000499676.2	TFDP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_235405679 Show fit	8.50	ENST00000390645.2	ARL4C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor-like 4C
chr3_-_48229846 Show fit	8.34	ENST00000302506.3 ENST00000351231.3 ENST00000437972.1	CDC25A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 25A
chr5_-_137548997 Show fit	8.16	ENST00000505120.1 ENST00000394886.2 ENST00000394884.3	CDC23 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 23
chr18_-_54318353 Show fit	8.08	ENST00000590954.1 ENST00000540155.1	TXNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin-like 1
chr17_+_48796905 Show fit	7.87	ENST00000505658.1 ENST00000393227.2 ENST00000240304.1 ENST00000311571.3 ENST00000505619.1 ENST00000544170.1 ENST00000510984.1	LUC7L3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LUC7-like 3 (S. cerevisiae)
chr1_+_86046433 Show fit	7.82	ENST00000451137.2	CYR61 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cysteine-rich, angiogenic inducer, 61
chr12_+_53848505 Show fit	7.80	ENST00000552819.1 ENST00000455667.3	PCBP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	poly(rC) binding protein 2
chr6_+_35995488 Show fit	7.80	ENST00000229795.3	MAPK14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase 14
chr13_+_45694583 Show fit	7.74	ENST00000340473.6	GTF2F2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	general transcription factor IIF, polypeptide 2, 30kDa
chr6_+_4021554 Show fit	7.73	ENST00000337659.6	PRPF4B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pre-mRNA processing factor 4B
chr5_+_74062806 Show fit	7.62	ENST00000296802.5	NSA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr2_-_17935059 Show fit	7.62	ENST00000448223.2 ENST00000381272.4 ENST00000351948.4	SMC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 6
chr6_+_27114861 Show fit	7.56	ENST00000377459.1	HIST1H2AH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histone cluster 1, H2ah
chr6_+_35995531 Show fit	7.34	ENST00000229794.4	MAPK14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase 14
chr6_-_160210715 Show fit	7.32	ENST00000392168.2 ENST00000321394.7	TCP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	t-complex 1
chr3_-_51975942 Show fit	7.21	ENST00000232888.6	RRP9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr2_-_203103185 Show fit	6.98	ENST00000409205.1	SUMO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 1
chr16_-_12009735 Show fit	6.80	ENST00000439887.2 ENST00000434724.2	GSPT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G1 to S phase transition 1
chr1_-_25747283 Show fit	6.75	ENST00000346452.4 ENST00000340849.4 ENST00000349438.4 ENST00000294413.7 ENST00000413854.1 ENST00000455194.1 ENST00000243186.6 ENST00000425135.1	RHCE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rh blood group, CcEe antigens
chr22_+_38201114 Show fit	6.74	ENST00000340857.2	H1F0 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	H1 histone family, member 0
chr1_-_23670752 Show fit	6.62	ENST00000302271.6 ENST00000426846.2 ENST00000427764.2 ENST00000606561.1 ENST00000374616.3	HNRNPR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein R
chr16_-_47495170 Show fit	6.55	ENST00000320640.6 ENST00000544001.2	ITFG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin alpha FG-GAP repeat containing 1
chr11_-_64545941 Show fit	6.50	ENST00000377387.1	SF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	splicing factor 1
chr19_+_2236509 Show fit	6.48	ENST00000221494.5	SF3A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	splicing factor 3a, subunit 2, 66kDa
chr6_+_135502501 Show fit	6.24	ENST00000527615.1 ENST00000420123.2 ENST00000525369.1 ENST00000528774.1 ENST00000534121.1 ENST00000534044.1 ENST00000533624.1	MYB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	v-myb avian myeloblastosis viral oncogene homolog
chr17_+_57642886 Show fit	6.22	ENST00000251241.4 ENST00000451169.2 ENST00000425628.3 ENST00000584385.1 ENST00000580030.1	DHX40 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr4_+_30721968 Show fit	6.08	ENST00000361762.2	PCDH7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin 7
chr17_-_56065484 Show fit	6.05	ENST00000581208.1	VEZF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vascular endothelial zinc finger 1
chr19_+_49588690 Show fit	6.03	ENST00000221448.5	SNRNP70 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein 70kDa (U1)

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
44.9	269.7	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
37.7	377.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
34.6	103.9	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
30.2	120.7	GO:0046452	dihydrofolate metabolic process(GO:0046452)
28.6	114.5	GO:0010216	maintenance of DNA methylation(GO:0010216)
28.2	141.1	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
24.5	147.1	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
17.4	52.3	GO:1904897	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
15.7	78.7	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
15.4	46.1	GO:0006597	spermine biosynthetic process(GO:0006597)
15.1	150.9	GO:0001833	inner cell mass cell proliferation(GO:0001833)
14.6	43.9	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
13.1	118.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
12.9	51.5	GO:0048478	replication fork protection(GO:0048478)
12.3	24.7	GO:0006272	leading strand elongation(GO:0006272)
11.7	81.6	GO:0000710	meiotic mismatch repair(GO:0000710)
11.3	33.9	GO:0016260	selenocysteine biosynthetic process(GO:0016260)
11.1	11.1	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
10.5	115.9	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
10.1	372.0	GO:0006270	DNA replication initiation(GO:0006270)
9.6	57.8	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
9.2	92.3	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
8.2	24.7	GO:0002184	cytoplasmic translational termination(GO:0002184)
8.1	187.0	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
8.1	24.4	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
7.8	31.1	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
7.4	29.4	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
6.6	39.3	GO:0035822	gene conversion(GO:0035822)
6.3	19.0	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
5.9	35.2	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
5.3	42.8	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
5.3	16.0	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
5.0	15.0	GO:0019477	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
4.5	9.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
4.5	35.7	GO:0010032	meiotic chromosome condensation(GO:0010032)
4.4	57.7	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
4.4	21.9	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
4.4	8.7	GO:0070602	regulation of centromeric sister chromatid cohesion(GO:0070602)
4.1	28.5	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
4.0	20.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
3.7	14.8	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
3.7	11.0	GO:0071789	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
3.5	17.3	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
3.4	20.6	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
3.3	13.2	GO:0021796	cerebral cortex regionalization(GO:0021796)
3.1	12.3	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
2.9	8.7	GO:0072428	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
2.8	22.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
2.6	23.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
2.5	27.5	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
2.4	12.1	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
2.2	35.0	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
2.0	35.5	GO:1904816	positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
1.9	24.5	GO:0045008	depyrimidination(GO:0045008)
1.9	11.2	GO:0061084	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
1.8	81.6	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
1.8	28.6	GO:0000338	protein deneddylation(GO:0000338)
1.8	86.5	GO:0006301	postreplication repair(GO:0006301)
1.7	17.3	GO:0009249	protein lipoylation(GO:0009249)
1.7	6.9	GO:0032954	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.7	8.5	GO:0032456	endocytic recycling(GO:0032456)
1.7	13.5	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
1.7	14.9	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.6	9.7	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
1.5	44.8	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
1.5	24.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
1.5	5.9	GO:0097167	circadian regulation of translation(GO:0097167)
1.5	5.8	GO:0031291	Ran protein signal transduction(GO:0031291)
1.4	41.3	GO:0043968	histone H2A acetylation(GO:0043968)
1.3	5.3	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
1.3	78.1	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
1.3	9.0	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
1.1	195.2	GO:0006338	chromatin remodeling(GO:0006338)
1.1	26.6	GO:0061157	mRNA destabilization(GO:0061157)
1.1	17.7	GO:0070734	histone H3-K27 methylation(GO:0070734)
1.1	7.6	GO:0000722	telomere maintenance via recombination(GO:0000722)
1.1	5.3	GO:0060356	leucine import(GO:0060356)
1.0	26.0	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.9	3.7	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.9	7.8	GO:0060591	apoptotic process involved in heart morphogenesis(GO:0003278) chondroblast differentiation(GO:0060591)
0.8	14.8	GO:0000732	strand displacement(GO:0000732)
0.8	18.3	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.8	2.3	GO:0061010	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) gall bladder development(GO:0061010)
0.8	13.5	GO:0002227	innate immune response in mucosa(GO:0002227)
0.7	15.4	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.7	2.2	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.7	5.7	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.7	3.4	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.7	54.6	GO:0045454	cell redox homeostasis(GO:0045454)
0.7	4.0	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.6	3.9	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.6	7.7	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.6	7.8	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.6	3.4	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.6	9.7	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.5	1.6	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
0.5	9.7	GO:0033197	response to vitamin E(GO:0033197)
0.5	49.6	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.5	8.2	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.5	3.3	GO:0001675	acrosome assembly(GO:0001675)
0.4	45.4	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.4	40.5	GO:0007062	sister chromatid cohesion(GO:0007062)
0.4	7.9	GO:0006376	mRNA splice site selection(GO:0006376)
0.4	16.4	GO:0006342	chromatin silencing(GO:0006342)
0.4	3.3	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.4	1.2	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.3	3.4	GO:0061314	Notch signaling involved in heart development(GO:0061314)
0.3	6.7	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.3	19.7	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.3	10.0	GO:0005980	glycogen catabolic process(GO:0005980)
0.3	9.9	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.3	88.0	GO:0007160	cell-matrix adhesion(GO:0007160)
0.3	7.6	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.2	3.9	GO:0006284	base-excision repair(GO:0006284)
0.2	17.9	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.2	1.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.2	3.2	GO:1903432	regulation of TORC1 signaling(GO:1903432)
0.2	12.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.2	4.1	GO:0008284	positive regulation of cell proliferation(GO:0008284)
0.1	1.8	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.1	4.8	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.1	1.8	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.1	3.9	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.1	25.8	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.1	11.6	GO:0016925	protein sumoylation(GO:0016925)
0.1	20.1	GO:0030336	negative regulation of cell migration(GO:0030336)
0.1	6.1	GO:0001885	endothelial cell development(GO:0001885)
0.1	5.8	GO:0001541	ovarian follicle development(GO:0001541)
0.1	21.7	GO:0044744	protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.1	3.7	GO:0046677	response to antibiotic(GO:0046677)
0.1	2.8	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	3.8	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	6.1	GO:0002576	platelet degranulation(GO:0002576)
0.0	7.2	GO:0006364	rRNA processing(GO:0006364)
0.0	0.2	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.0	GO:0042023	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0033504	floor plate development(GO:0033504)
0.0	0.5	GO:0051865	protein autoubiquitination(GO:0051865)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
53.9	269.7	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
46.7	187.0	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
45.4	589.9	GO:0042555	MCM complex(GO:0042555)
33.8	135.3	GO:0000811	GINS complex(GO:0000811)
24.4	97.7	GO:0032301	MutSalpha complex(GO:0032301)
16.2	48.6	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
15.1	45.4	GO:0005873	plus-end kinesin complex(GO:0005873)
14.3	86.0	GO:0031298	replication fork protection complex(GO:0031298)
14.2	199.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
13.5	40.4	GO:0035189	Rb-E2F complex(GO:0035189)
12.8	102.7	GO:0016012	sarcoglycan complex(GO:0016012)
11.1	11.1	GO:0031261	DNA replication preinitiation complex(GO:0031261)
10.3	41.3	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
9.3	83.9	GO:0000796	condensin complex(GO:0000796)
9.2	46.2	GO:0033503	HULC complex(GO:0033503)
9.2	73.9	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
8.4	41.8	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
8.2	24.7	GO:0018444	translation release factor complex(GO:0018444)
8.2	24.7	GO:0070557	PCNA-p21 complex(GO:0070557)
8.0	103.9	GO:0045120	pronucleus(GO:0045120)
7.9	102.4	GO:0005721	pericentric heterochromatin(GO:0005721)
7.5	59.8	GO:0034715	pICln-Sm protein complex(GO:0034715)
7.4	29.4	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
7.0	20.9	GO:0030893	meiotic cohesin complex(GO:0030893)
6.8	47.5	GO:0016589	NURF complex(GO:0016589)
6.1	24.4	GO:0031510	SUMO activating enzyme complex(GO:0031510)
5.5	43.9	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
4.8	57.7	GO:0044615	nuclear pore nuclear basket(GO:0044615)
4.6	27.6	GO:0001739	sex chromatin(GO:0001739)
4.5	18.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
4.5	44.8	GO:0034709	methylosome(GO:0034709)
3.9	11.8	GO:1903349	omegasome membrane(GO:1903349)
3.9	31.1	GO:0070552	BRISC complex(GO:0070552)
3.8	19.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
3.7	48.6	GO:0001673	male germ cell nucleus(GO:0001673)
3.7	11.0	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
3.5	17.3	GO:0035061	interchromatin granule(GO:0035061)
3.4	3.4	GO:0032302	MutSbeta complex(GO:0032302)
2.6	7.7	GO:0005674	transcription factor TFIIF complex(GO:0005674)
2.4	7.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
2.2	15.4	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
2.1	15.0	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
2.0	12.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
1.9	13.5	GO:0005956	protein kinase CK2 complex(GO:0005956)
1.7	8.7	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
1.6	12.5	GO:0072546	ER membrane protein complex(GO:0072546)
1.5	26.7	GO:0016580	Sin3 complex(GO:0016580)
1.4	78.7	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
1.3	25.5	GO:0071004	U2-type prespliceosome(GO:0071004)
1.3	17.3	GO:0002199	zona pellucida receptor complex(GO:0002199)
1.2	6.9	GO:0044613	nuclear pore central transport channel(GO:0044613)
1.1	10.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
1.1	5.3	GO:0033553	rDNA heterochromatin(GO:0033553)
1.1	20.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
1.0	87.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
1.0	9.7	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
1.0	20.9	GO:0035861	site of double-strand break(GO:0035861)
0.9	17.9	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.8	23.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.8	3.9	GO:0034457	Mpp10 complex(GO:0034457)
0.8	53.0	GO:0005637	nuclear inner membrane(GO:0005637)
0.8	16.0	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.8	9.0	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.6	28.6	GO:0008180	COP9 signalosome(GO:0008180)
0.6	102.2	GO:0000775	chromosome, centromeric region(GO:0000775)
0.5	3.2	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4	57.9	GO:0016363	nuclear matrix(GO:0016363)
0.4	29.5	GO:0000793	condensed chromosome(GO:0000793)
0.4	30.0	GO:0005643	nuclear pore(GO:0005643)
0.4	1.1	GO:1990075	periciliary membrane compartment(GO:1990075)
0.3	4.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3	30.7	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.3	21.1	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3	57.3	GO:0005819	spindle(GO:0005819)
0.3	8.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.3	7.6	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.2	6.7	GO:0005719	nuclear euchromatin(GO:0005719)
0.2	21.6	GO:0005681	spliceosomal complex(GO:0005681)
0.2	6.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	97.3	GO:0005874	microtubule(GO:0005874)
0.2	26.2	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.2	5.9	GO:0016592	mediator complex(GO:0016592)
0.2	25.6	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.2	2.3	GO:0000785	chromatin(GO:0000785)
0.2	4.0	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	3.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	41.9	GO:0005635	nuclear envelope(GO:0005635)
0.1	6.8	GO:0000781	chromosome, telomeric region(GO:0000781)
0.1	101.0	GO:0005730	nucleolus(GO:0005730)
0.1	7.2	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	8.1	GO:0000502	proteasome complex(GO:0000502)
0.1	4.8	GO:0031201	SNARE complex(GO:0031201)
0.0	0.2	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.0	5.3	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	30.6	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	7.8	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	7.8	GO:0005925	focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
46.7	187.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
24.4	97.7	GO:0032143	single thymine insertion binding(GO:0032143)
22.3	200.5	GO:1990226	histone methyltransferase binding(GO:1990226)
20.1	120.7	GO:0051870	methotrexate binding(GO:0051870)
18.0	71.9	GO:0036033	mediator complex binding(GO:0036033)
17.1	102.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
15.2	258.1	GO:0003688	DNA replication origin binding(GO:0003688)
14.6	131.5	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
11.3	33.9	GO:0004756	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
11.3	135.3	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
11.2	269.7	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
10.7	42.8	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
9.4	28.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
8.8	43.9	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
8.4	268.1	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
7.1	71.0	GO:1990446	U1 snRNP binding(GO:1990446)
6.9	20.6	GO:0004137	deoxycytidine kinase activity(GO:0004137)
6.4	44.8	GO:0050733	RS domain binding(GO:0050733)
5.9	35.2	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
5.8	17.3	GO:0031177	acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
4.9	29.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
4.4	31.1	GO:0008732	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
4.1	24.7	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
4.1	12.3	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
3.9	3.9	GO:0000405	bubble DNA binding(GO:0000405)
3.7	15.0	GO:0016748	succinyltransferase activity(GO:0016748)
3.1	24.5	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
3.0	24.4	GO:0044388	small protein activating enzyme binding(GO:0044388)
3.0	9.1	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.9	57.7	GO:0043495	protein anchor(GO:0043495)
2.7	78.9	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
2.7	5.3	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.5	9.9	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
2.3	16.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
2.2	46.5	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
2.0	44.8	GO:0008327	methyl-CpG binding(GO:0008327)
2.0	5.9	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
1.9	192.7	GO:0070491	repressing transcription factor binding(GO:0070491)
1.7	17.3	GO:0051525	NFAT protein binding(GO:0051525)
1.5	16.9	GO:0098505	single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
1.5	89.4	GO:0035064	methylated histone binding(GO:0035064)
1.3	7.8	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
1.3	14.0	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.3	13.9	GO:0019869	chloride channel inhibitor activity(GO:0019869)
1.2	7.2	GO:0034511	U3 snoRNA binding(GO:0034511)
1.2	11.6	GO:0031386	protein tag(GO:0031386)
1.2	8.1	GO:0047134	protein-disulfide reductase activity(GO:0047134)
1.2	55.3	GO:0008536	Ran GTPase binding(GO:0008536)
1.1	10.0	GO:0004689	phosphorylase kinase activity(GO:0004689)
1.1	38.4	GO:0036002	pre-mRNA binding(GO:0036002)
1.1	46.2	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
1.0	137.8	GO:0042393	histone binding(GO:0042393)
1.0	125.0	GO:0004386	helicase activity(GO:0004386)
0.8	4.0	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.7	6.9	GO:0051425	PTB domain binding(GO:0051425)
0.7	61.6	GO:0033613	activating transcription factor binding(GO:0033613)
0.6	18.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.6	6.7	GO:0003680	AT DNA binding(GO:0003680)
0.6	9.7	GO:0004526	ribonuclease P activity(GO:0004526)
0.6	3.4	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.6	20.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.5	45.4	GO:0003777	microtubule motor activity(GO:0003777)
0.5	5.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.5	28.2	GO:0003684	damaged DNA binding(GO:0003684)
0.5	46.1	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.5	17.3	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.4	11.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.4	19.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.4	5.6	GO:0016018	cyclosporin A binding(GO:0016018)
0.4	25.8	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3	69.1	GO:0008201	heparin binding(GO:0008201)
0.3	8.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.3	99.7	GO:0015631	tubulin binding(GO:0015631)
0.3	26.6	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.3	41.5	GO:0047485	protein N-terminus binding(GO:0047485)
0.3	67.4	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.3	3.7	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.3	27.2	GO:0008565	protein transporter activity(GO:0008565)
0.2	3.8	GO:0048038	quinone binding(GO:0048038)
0.2	36.5	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.2	1.8	GO:0031593	polyubiquitin binding(GO:0031593)
0.2	3.9	GO:0030515	snoRNA binding(GO:0030515)
0.2	17.9	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	12.1	GO:0003725	double-stranded RNA binding(GO:0003725)
0.2	12.5	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.2	16.0	GO:0032947	protein complex scaffold(GO:0032947)
0.1	5.9	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	58.4	GO:0008134	transcription factor binding(GO:0008134)
0.1	22.8	GO:0008022	protein C-terminus binding(GO:0008022)
0.1	27.5	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.1	48.1	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.1	9.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	1.2	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	0.3	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	38.7	GO:0005198	structural molecule activity(GO:0005198)
0.1	6.2	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	31.9	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	1.1	GO:0051082	unfolded protein binding(GO:0051082)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
20.8	290.8	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
7.2	129.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
4.9	587.5	PID E2F PATHWAY	E2F transcription factor network
3.2	182.1	PID ATR PATHWAY	ATR signaling pathway
2.9	97.4	PID ATM PATHWAY	ATM pathway
2.5	203.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
2.2	24.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
2.0	63.5	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
1.1	52.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.9	46.3	PID PLK1 PATHWAY	PLK1 signaling events
0.9	94.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.8	35.7	PID AURORA B PATHWAY	Aurora B signaling
0.6	13.5	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.4	31.2	PID LKB1 PATHWAY	LKB1 signaling events
0.3	26.9	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.3	8.7	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.3	7.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	29.9	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.2	9.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	8.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	3.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	3.4	PID NOTCH PATHWAY	Notch signaling pathway
0.1	3.2	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	3.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	1.8	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
45.3	725.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
25.5	687.4	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
9.2	128.8	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
5.1	76.7	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
3.5	69.8	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
2.8	55.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
2.4	42.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
2.2	115.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
2.1	120.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
2.1	185.4	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
2.0	22.0	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
1.8	46.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
1.8	156.6	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
1.7	64.6	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
1.7	8.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
1.7	45.4	REACTOME KINESINS	Genes involved in Kinesins
1.3	78.1	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
1.1	15.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.1	34.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.1	14.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.0	24.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
1.0	17.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.8	20.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.6	15.0	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.6	55.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.5	28.5	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.5	15.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.5	3.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.5	8.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5	35.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.4	16.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.4	52.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.4	8.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.4	10.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	9.9	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.3	17.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	19.2	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.2	46.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.2	13.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.2	13.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	32.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2	14.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.2	4.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	5.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.8	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	19.2	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.1	1.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels