GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
E2F3 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000112242.10	E2F transcription factor 3

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2F3	hg19_v2_chr6_+_20403997_20404034	0.59	3.8e-22	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr15_-_91537723 Show fit	68.65	ENST00000394249.3 ENST00000559811.1 ENST00000442656.2 ENST00000557905.1 ENST00000361919.3	PRC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein regulator of cytokinesis 1
chr17_+_73201754 Show fit	63.43	ENST00000583569.1 ENST00000245544.4 ENST00000579324.1 ENST00000541827.1 ENST00000579298.1 ENST00000447371.2	NUP85 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 85kDa
chr10_-_58120996 Show fit	54.71	ENST00000361148.6 ENST00000395405.1 ENST00000373944.3	ZWINT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ZW10 interacting kinetochore protein
chr5_+_177631497 Show fit	46.01	ENST00000358344.3	HNRNPAB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein A/B
chr2_+_10262857 Show fit	44.05	ENST00000304567.5	RRM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonucleotide reductase M2
chr10_+_62538248 Show fit	42.45	ENST00000448257.2	CDK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 1
chr18_-_54318353 Show fit	41.49	ENST00000590954.1 ENST00000540155.1	TXNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin-like 1
chr20_+_25388293 Show fit	41.20	ENST00000262460.4 ENST00000429262.2	GINS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GINS complex subunit 1 (Psf1 homolog)
chr10_+_62538089 Show fit	39.75	ENST00000519078.2 ENST00000395284.3 ENST00000316629.4	CDK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 1
chr19_-_55919087 Show fit	39.55	ENST00000587845.1 ENST00000589978.1 ENST00000264552.9	UBE2S Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2S
chr3_+_112709804 Show fit	38.25	ENST00000383677.3	GTPBP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GTP-binding protein 8 (putative)
chr6_-_38670897 Show fit	36.93	ENST00000373365.4	GLO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glyoxalase I
chr2_+_181845843 Show fit	35.69	ENST00000602710.1	UBE2E3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2E 3
chr8_-_101963482 Show fit	34.90	ENST00000419477.2	YWHAZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_-_185542817 Show fit	34.70	ENST00000382199.2	IGF2BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like growth factor 2 mRNA binding protein 2
chr11_-_14380664 Show fit	34.58	ENST00000545643.1 ENST00000256196.4	RRAS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	related RAS viral (r-ras) oncogene homolog 2
chr11_+_118272328 Show fit	34.51	ENST00000524422.1	ATP5L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr7_+_26240776 Show fit	34.26	ENST00000337620.4	CBX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 3
chr1_+_203830703 Show fit	33.49	ENST00000414487.2	SNRPE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptide E
chr14_+_51706886 Show fit	33.34	ENST00000457354.2	TMX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin-related transmembrane protein 1
chr5_+_159848807 Show fit	33.00	ENST00000352433.5	PTTG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pituitary tumor-transforming 1
chr9_-_179018 Show fit	32.92	ENST00000431099.2 ENST00000382447.4 ENST00000382389.1 ENST00000377447.3 ENST00000314367.10 ENST00000356521.4 ENST00000382393.1 ENST00000377400.4	CBWD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COBW domain containing 1
chr8_+_91013676 Show fit	32.74	ENST00000519410.1 ENST00000522161.1 ENST00000517761.1 ENST00000520227.1	DECR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	2,4-dienoyl CoA reductase 1, mitochondrial
chr6_+_52535878 Show fit	32.47	ENST00000211314.4	TMEM14A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 14A
chr15_-_72523454 Show fit	32.26	ENST00000565154.1 ENST00000565184.1 ENST00000389093.3 ENST00000449901.2 ENST00000335181.5 ENST00000319622.6	PKM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pyruvate kinase, muscle
chr20_-_60718430 Show fit	32.00	ENST00000370873.4 ENST00000370858.3	PSMA7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 7
chr2_+_181845298 Show fit	31.72	ENST00000410062.4	UBE2E3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2E 3
chr8_-_81083341 Show fit	31.63	ENST00000519303.2	TPD52 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor protein D52
chr1_+_155178481 Show fit	31.60	ENST00000368376.3	MTX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	metaxin 1
chr1_-_43638168 Show fit	31.26	ENST00000431635.2	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EBNA1 binding protein 2
chr15_-_66649010 Show fit	31.15	ENST00000367709.4 ENST00000261881.4	TIPIN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TIMELESS interacting protein
chr7_-_140714739 Show fit	31.13	ENST00000467334.1 ENST00000324787.5	MRPS33 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S33
chr3_+_52740094 Show fit	30.32	ENST00000602728.1	SPCS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr2_-_69664549 Show fit	30.32	ENST00000450796.2 ENST00000484177.1	NFU1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr12_+_104609550 Show fit	30.27	ENST00000525566.1 ENST00000429002.2	TXNRD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin reductase 1
chr5_+_159848854 Show fit	30.24	ENST00000517480.1 ENST00000520452.1 ENST00000393964.1	PTTG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pituitary tumor-transforming 1
chr2_+_113403434 Show fit	30.23	ENST00000272542.3	SLC20A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 20 (phosphate transporter), member 1
chr15_-_55489097 Show fit	30.10	ENST00000260443.4	RSL24D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal L24 domain containing 1
chr16_-_85833160 Show fit	29.96	ENST00000435200.2	EMC8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ER membrane protein complex subunit 8
chr17_+_73257742 Show fit	29.84	ENST00000579761.1 ENST00000245539.6	MRPS7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S7
chr7_-_96339132 Show fit	29.67	ENST00000413065.1	SHFM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	split hand/foot malformation (ectrodactyly) type 1
chr5_+_32585605 Show fit	28.51	ENST00000265073.4 ENST00000515355.1 ENST00000502897.1 ENST00000510442.1	SUB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SUB1 homolog (S. cerevisiae)
chr12_-_50419177 Show fit	28.50	ENST00000454520.2 ENST00000546595.1 ENST00000548824.1 ENST00000549777.1 ENST00000546723.1 ENST00000427314.2 ENST00000552157.1 ENST00000552310.1 ENST00000548644.1 ENST00000312377.5 ENST00000546786.1 ENST00000550149.1 ENST00000546764.1 ENST00000552004.1 ENST00000548320.1 ENST00000547905.1 ENST00000550651.1 ENST00000551145.1 ENST00000434422.1 ENST00000552921.1	RACGAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rac GTPase activating protein 1
chr7_+_16685756 Show fit	28.34	ENST00000415365.1 ENST00000258761.3 ENST00000433922.2 ENST00000452975.2 ENST00000405202.1	BZW2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	basic leucine zipper and W2 domains 2
chr2_+_201171372 Show fit	28.18	ENST00000409140.3	SPATS2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermatogenesis associated, serine-rich 2-like
chr8_-_48872686 Show fit	28.01	ENST00000314191.2 ENST00000338368.3	PRKDC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase, DNA-activated, catalytic polypeptide
chr14_-_68141535 Show fit	27.76	ENST00000554659.1	VTI1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vesicle transport through interaction with t-SNAREs 1B
chrX_-_153285395 Show fit	27.73	ENST00000369980.3	IRAK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin-1 receptor-associated kinase 1
chr5_+_177631523 Show fit	27.70	ENST00000506339.1 ENST00000355836.5 ENST00000514633.1 ENST00000515193.1 ENST00000506259.1 ENST00000504898.1	HNRNPAB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein A/B
chr1_-_54411240 Show fit	27.59	ENST00000371378.2	HSPB11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock protein family B (small), member 11
chr19_+_33071974 Show fit	27.47	ENST00000590247.2 ENST00000419343.3 ENST00000592786.1 ENST00000379316.3	PDCD5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	programmed cell death 5
chr5_+_1801503 Show fit	27.46	ENST00000274137.5 ENST00000469176.1	NDUFS6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr13_+_28194873 Show fit	27.32	ENST00000302979.3	POLR1D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) I polypeptide D, 16kDa
chr10_-_17659234 Show fit	27.26	ENST00000466335.1	PTPLA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr14_-_104029013 Show fit	27.09	ENST00000299204.4 ENST00000557666.1	BAG5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-associated athanogene 5
chr9_-_70490107 Show fit	26.99	ENST00000377395.4 ENST00000429800.2 ENST00000430059.2 ENST00000377384.1 ENST00000382405.3	CBWD5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COBW domain containing 5
chr7_-_140714430 Show fit	26.88	ENST00000393008.3	MRPS33 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S33
chr9_+_100745615 Show fit	26.73	ENST00000339399.4	ANP32B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr19_-_14628645 Show fit	26.64	ENST00000598235.1	DNAJB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 1
chr9_-_111775772 Show fit	26.46	ENST00000325580.6 ENST00000374593.4 ENST00000374595.4 ENST00000325551.4	CTNNAL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	catenin (cadherin-associated protein), alpha-like 1
chr2_-_10587897 Show fit	26.32	ENST00000405333.1 ENST00000443218.1	ODC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ornithine decarboxylase 1
chr10_+_124913930 Show fit	26.31	ENST00000368858.5	BUB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BUB3 mitotic checkpoint protein
chr5_-_68665469 Show fit	26.21	ENST00000217893.5	TAF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr6_+_36562132 Show fit	26.19	ENST00000373715.6 ENST00000339436.7	SRSF3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 3
chr3_-_185542761 Show fit	26.05	ENST00000457616.2 ENST00000346192.3	IGF2BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like growth factor 2 mRNA binding protein 2
chr19_-_6415695 Show fit	25.70	ENST00000594496.1 ENST00000594745.1 ENST00000600480.1	KHSRP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KH-type splicing regulatory protein
chr3_-_134093275 Show fit	25.67	ENST00000513145.1 ENST00000422605.2	AMOTL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	angiomotin like 2
chr2_+_237994519 Show fit	25.65	ENST00000392008.2 ENST00000409334.1 ENST00000409629.1	COPS8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COP9 signalosome subunit 8
chr13_-_22178284 Show fit	25.40	ENST00000468222.2 ENST00000382374.4	MICU2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial calcium uptake 2
chr7_-_86849025 Show fit	25.33	ENST00000257637.3	TMEM243 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 243, mitochondrial
chr5_-_68665084 Show fit	24.71	ENST00000509462.1	TAF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr5_+_5422778 Show fit	24.63	ENST00000296564.7	KIAA0947 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0947
chr12_+_93861264 Show fit	24.46	ENST00000549982.1 ENST00000361630.2	MRPL42 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L42
chr1_-_43637915 Show fit	24.43	ENST00000236051.2	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EBNA1 binding protein 2
chr12_+_93861282 Show fit	24.27	ENST00000552217.1 ENST00000393128.4 ENST00000547098.1	MRPL42 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L42
chr14_+_97263641 Show fit	24.26	ENST00000216639.3	VRK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vaccinia related kinase 1
chr7_+_141438118 Show fit	24.15	ENST00000265304.6 ENST00000498107.1 ENST00000467681.1 ENST00000465582.1 ENST00000463093.1	SSBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	single-stranded DNA binding protein 1, mitochondrial
chr10_+_95256356 Show fit	24.04	ENST00000371485.3	CEP55 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centrosomal protein 55kDa
chr5_-_68665815 Show fit	23.93	ENST00000380818.3 ENST00000328663.4	TAF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr20_-_54967187 Show fit	23.79	ENST00000422322.1 ENST00000371356.2 ENST00000451915.1 ENST00000347343.2 ENST00000395911.1 ENST00000395907.1 ENST00000441357.1 ENST00000456249.1 ENST00000420474.1 ENST00000395909.4 ENST00000395914.1 ENST00000312783.6 ENST00000395915.3 ENST00000395913.3	AURKA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aurora kinase A
chr2_+_200820269 Show fit	23.78	ENST00000392290.1	C2orf47 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 2 open reading frame 47
chr2_-_170681324 Show fit	23.73	ENST00000409340.1	METTL5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methyltransferase like 5
chr14_+_20937538 Show fit	23.67	ENST00000361505.5 ENST00000553591.1	PNP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	purine nucleoside phosphorylase
chr15_+_48623600 Show fit	23.51	ENST00000558813.1 ENST00000331200.3 ENST00000558472.1	DUT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	deoxyuridine triphosphatase
chr14_-_102553371 Show fit	23.39	ENST00000553585.1 ENST00000216281.8	HSP90AA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr1_-_54411255 Show fit	23.37	ENST00000371377.3	HSPB11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock protein family B (small), member 11
chr2_-_69664586 Show fit	23.30	ENST00000303698.3 ENST00000394305.1 ENST00000410022.2	NFU1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr1_+_948803 Show fit	23.23	ENST00000379389.4	ISG15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ISG15 ubiquitin-like modifier
chr15_-_101835414 Show fit	23.10	ENST00000254193.6	SNRPA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptide A'
chr1_+_155178518 Show fit	22.96	ENST00000316721.4	MTX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	metaxin 1
chr4_-_100871506 Show fit	22.84	ENST00000296417.5	H2AFZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	H2A histone family, member Z
chr20_+_47662805 Show fit	22.72	ENST00000262982.2 ENST00000542325.1	CSE1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CSE1 chromosome segregation 1-like (yeast)
chr4_-_170679024 Show fit	22.72	ENST00000393381.2	C4orf27 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 4 open reading frame 27
chr15_-_101835110 Show fit	22.69	ENST00000560496.1	SNRPA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptide A'
chr11_+_105948216 Show fit	22.51	ENST00000278618.4	AASDHPPT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr20_-_31989307 Show fit	22.45	ENST00000473997.1 ENST00000544843.1 ENST00000346416.2 ENST00000357886.4 ENST00000339269.5	CDK5RAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CDK5 regulatory subunit associated protein 1
chr18_+_657733 Show fit	22.19	ENST00000323250.5 ENST00000323224.7	TYMS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thymidylate synthetase
chr4_-_1714037 Show fit	22.10	ENST00000488267.1 ENST00000429429.2 ENST00000480936.1	SLBP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stem-loop binding protein
chr2_+_48010312 Show fit	22.10	ENST00000540021.1	MSH6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mutS homolog 6
chr2_+_181845074 Show fit	22.09	ENST00000602959.1 ENST00000602479.1 ENST00000392415.2 ENST00000602291.1	UBE2E3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2E 3
chr2_+_264869 Show fit	22.03	ENST00000272067.6 ENST00000272065.5 ENST00000407983.3	ACP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acid phosphatase 1, soluble
chr9_+_127624387 Show fit	22.02	ENST00000353214.2	ARPC5L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 5-like
chr11_+_18416103 Show fit	21.84	ENST00000543445.1 ENST00000430553.2 ENST00000396222.2 ENST00000535451.1	LDHA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lactate dehydrogenase A
chr15_+_77224045 Show fit	21.84	ENST00000320963.5 ENST00000394883.3	RCN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	reticulocalbin 2, EF-hand calcium binding domain
chr9_+_70856899 Show fit	21.79	ENST00000377342.5 ENST00000478048.1	CBWD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COBW domain containing 3
chr7_+_12727250 Show fit	21.78	ENST00000404894.1	ARL4A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor-like 4A
chr4_-_185655278 Show fit	21.73	ENST00000281453.5	MLF1IP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein U
chr17_-_47785265 Show fit	21.68	ENST00000511763.1 ENST00000515850.1 ENST00000415270.2 ENST00000240333.6	SLC35B1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 35, member B1
chr15_-_85259294 Show fit	21.67	ENST00000558217.1 ENST00000558196.1 ENST00000558134.1	SEC11A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEC11 homolog A (S. cerevisiae)
chr6_-_5261141 Show fit	21.62	ENST00000330636.4 ENST00000500576.2	LYRM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LYR motif containing 4
chr4_-_1713977 Show fit	21.57	ENST00000318386.4	SLBP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stem-loop binding protein
chr19_-_48894762 Show fit	21.57	ENST00000600980.1 ENST00000330720.2	KDELR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr1_-_211752073 Show fit	21.56	ENST00000367001.4	SLC30A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 30 (zinc transporter), member 1
chr8_+_91013577 Show fit	21.54	ENST00000220764.2	DECR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	2,4-dienoyl CoA reductase 1, mitochondrial
chr1_+_8021713 Show fit	21.49	ENST00000338639.5 ENST00000493678.1 ENST00000377493.5	PARK7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	parkinson protein 7
chr3_-_134093395 Show fit	21.46	ENST00000249883.5	AMOTL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	angiomotin like 2
chr4_-_2965052 Show fit	21.41	ENST00000398071.4 ENST00000502735.1 ENST00000314262.6 ENST00000416614.2	NOP14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NOP14 nucleolar protein
chr1_+_44440575 Show fit	21.31	ENST00000532642.1 ENST00000236067.4 ENST00000471859.2	ATP6V0B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr12_-_112856623 Show fit	21.31	ENST00000551291.2	RPL6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L6
chr1_+_87170577 Show fit	21.29	ENST00000482504.1	SH3GLB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3-domain GRB2-like endophilin B1
chr21_-_40555393 Show fit	21.28	ENST00000380900.2	PSMG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) assembly chaperone 1
chr3_+_172468472 Show fit	21.28	ENST00000232458.5 ENST00000392692.3	ECT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	epithelial cell transforming sequence 2 oncogene
chr12_-_15942503 Show fit	21.22	ENST00000281172.5	EPS8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	epidermal growth factor receptor pathway substrate 8
chr11_+_102217936 Show fit	21.15	ENST00000532832.1 ENST00000530675.1 ENST00000533742.1 ENST00000227758.2 ENST00000532672.1 ENST00000531259.1 ENST00000527465.1	BIRC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	baculoviral IAP repeat containing 2
chr8_+_26149007 Show fit	21.11	ENST00000380737.3 ENST00000524169.1	PPP2R2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2, regulatory subunit B, alpha
chr14_+_58711539 Show fit	20.88	ENST00000216455.4 ENST00000412908.2 ENST00000557508.1	PSMA3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 3
chr22_-_29949634 Show fit	20.84	ENST00000397872.1 ENST00000397871.1 ENST00000440771.1	THOC5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	THO complex 5
chr13_+_76123883 Show fit	20.81	ENST00000377595.3	UCHL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr9_-_69262509 Show fit	20.74	ENST00000377449.1 ENST00000382399.4 ENST00000377439.1 ENST00000377441.1 ENST00000377457.5	CBWD6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COBW domain containing 6
chr7_-_16685422 Show fit	20.67	ENST00000306999.2	ANKMY2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat and MYND domain containing 2
chr15_+_59397275 Show fit	20.64	ENST00000288207.2	CCNB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin B2
chr2_-_47168850 Show fit	20.63	ENST00000409207.1	MCFD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	multiple coagulation factor deficiency 2
chr10_+_43278217 Show fit	20.63	ENST00000374518.5	BMS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BMS1 ribosome biogenesis factor
chr4_-_120988229 Show fit	20.62	ENST00000296509.6	MAD2L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MAD2 mitotic arrest deficient-like 1 (yeast)
chr2_+_114195268 Show fit	20.62	ENST00000259199.4 ENST00000416503.2 ENST00000433343.2	CBWD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COBW domain containing 2
chr6_-_79787902 Show fit	20.52	ENST00000275034.4	PHIP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pleckstrin homology domain interacting protein
chr12_+_133264635 Show fit	20.49	ENST00000545677.1 ENST00000537262.1	PXMP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit RP13-672B3.2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxisomal membrane protein 2, 22kDa Uncharacterized protein
chr5_+_10250328 Show fit	20.45	ENST00000515390.1	CCT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chaperonin containing TCP1, subunit 5 (epsilon)
chr19_-_23941639 Show fit	20.39	ENST00000395385.3 ENST00000531570.1 ENST00000528059.1	ZNF681 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 681
chr1_-_32801825 Show fit	20.39	ENST00000329421.7	MARCKSL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MARCKS-like 1
chr5_-_143550159 Show fit	20.34	ENST00000448443.2 ENST00000513112.1 ENST00000519064.1 ENST00000274496.5	YIPF5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Yip1 domain family, member 5
chr3_+_139063372 Show fit	20.24	ENST00000478464.1	MRPS22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S22
chr14_+_54863739 Show fit	20.06	ENST00000541304.1	CDKN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase inhibitor 3
chrX_-_153718953 Show fit	20.06	ENST00000369649.4 ENST00000393586.1	SLC10A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 10, member 3
chr6_+_10748019 Show fit	20.05	ENST00000543878.1 ENST00000461342.1 ENST00000475942.1 ENST00000379530.3 ENST00000473276.1 ENST00000481240.1 ENST00000467317.1	SYCP2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit TMEM14B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptonemal complex protein 2-like transmembrane protein 14B
chr5_+_112196919 Show fit	20.04	ENST00000505459.1 ENST00000282999.3 ENST00000515463.1	SRP19 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal recognition particle 19kDa
chr9_-_95055956 Show fit	19.99	ENST00000375629.3 ENST00000447699.2 ENST00000375643.3 ENST00000395554.3	IARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	isoleucyl-tRNA synthetase
chrX_-_153707246 Show fit	19.84	ENST00000407062.1	LAGE3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	L antigen family, member 3
chr15_-_72523924 Show fit	19.70	ENST00000566809.1 ENST00000567087.1 ENST00000569050.1 ENST00000568883.1	PKM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pyruvate kinase, muscle
chr18_-_47018897 Show fit	19.67	ENST00000418495.1	RPL17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L17
chr1_+_90287480 Show fit	19.45	ENST00000394593.3	LRRC8D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 8 family, member D
chr15_+_59397298 Show fit	19.45	ENST00000559622.1	CCNB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin B2
chr7_-_64023441 Show fit	19.44	ENST00000309683.6	ZNF680 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 680
chr1_+_161719552 Show fit	19.43	ENST00000367943.4	DUSP12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 12
chr7_+_98923505 Show fit	19.43	ENST00000432884.2 ENST00000262942.5	ARPC1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 1A, 41kDa
chr7_+_73097890 Show fit	19.37	ENST00000265758.2 ENST00000423166.2 ENST00000423497.1	WBSCR22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Williams Beuren syndrome chromosome region 22
chr1_+_155658849 Show fit	19.34	ENST00000368336.5 ENST00000343043.3 ENST00000421487.2 ENST00000535183.1 ENST00000465375.1 ENST00000470830.1	DAP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	death associated protein 3
chr14_-_104028595 Show fit	19.29	ENST00000337322.4 ENST00000445922.2	BAG5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-associated athanogene 5
chr19_+_49497121 Show fit	19.27	ENST00000413176.2	RUVBL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RuvB-like AAA ATPase 2
chr15_-_85259330 Show fit	19.21	ENST00000560266.1	SEC11A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEC11 homolog A (S. cerevisiae)
chr11_+_70049269 Show fit	19.12	ENST00000301838.4	FADD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Fas (TNFRSF6)-associated via death domain
chr19_-_10530784 Show fit	19.04	ENST00000593124.1	CDC37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 37
chr1_+_161284047 Show fit	19.00	ENST00000367975.2 ENST00000342751.4 ENST00000432287.2 ENST00000392169.2 ENST00000513009.1	SDHC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chr8_-_80942139 Show fit	19.00	ENST00000521434.1 ENST00000519120.1 ENST00000520946.1	MRPS28 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S28
chr4_+_17812525 Show fit	18.99	ENST00000251496.2	NCAPG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	non-SMC condensin I complex, subunit G
chr10_+_124913793 Show fit	18.97	ENST00000368865.4 ENST00000538238.1 ENST00000368859.2	BUB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BUB3 mitotic checkpoint protein
chr5_+_34915444 Show fit	18.91	ENST00000336767.5	BRIX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr12_+_57623869 Show fit	18.89	ENST00000414700.3 ENST00000557703.1	SHMT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 2 (mitochondrial)
chr14_+_54863682 Show fit	18.79	ENST00000543789.2 ENST00000442975.2 ENST00000458126.2 ENST00000556102.2	CDKN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase inhibitor 3
chr15_+_66797455 Show fit	18.79	ENST00000446801.2	ZWILCH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zwilch kinetochore protein
chr20_-_57617831 Show fit	18.77	ENST00000371033.5 ENST00000355937.4	SLMO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	slowmo homolog 2 (Drosophila)
chr1_-_8938736 Show fit	18.57	ENST00000234590.4	ENO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enolase 1, (alpha)
chr18_+_20513278 Show fit	18.53	ENST00000327155.5	RBBP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoblastoma binding protein 8
chr17_+_1944790 Show fit	18.51	ENST00000575162.1	DPH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	diphthamide biosynthesis 1
chr18_-_47018769 Show fit	18.51	ENST00000583637.1 ENST00000578528.1 ENST00000578532.1 ENST00000580387.1 ENST00000579248.1 ENST00000581373.1	RPL17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L17
chr2_-_207024134 Show fit	18.49	ENST00000457011.1 ENST00000440274.1 ENST00000432169.1	NDUFS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_-_42588338 Show fit	18.27	ENST00000234301.2	COX7A2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome c oxidase subunit VIIa polypeptide 2 like
chr1_+_166808692 Show fit	18.25	ENST00000367876.4	POGK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pogo transposable element with KRAB domain
chr2_-_84686552 Show fit	18.15	ENST00000393868.2	SUCLG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	succinate-CoA ligase, alpha subunit
chr15_+_48623208 Show fit	18.14	ENST00000559935.1 ENST00000559416.1	DUT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	deoxyuridine triphosphatase
chr3_+_158519654 Show fit	18.09	ENST00000415822.2 ENST00000392813.4 ENST00000264266.8	MFSD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major facilitator superfamily domain containing 1
chr9_+_116037922 Show fit	18.08	ENST00000374198.4	PRPF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pre-mRNA processing factor 4
chr2_-_170430277 Show fit	18.05	ENST00000438035.1 ENST00000453929.2	FASTKD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FAST kinase domains 1
chr3_+_151986709 Show fit	18.02	ENST00000495875.2 ENST00000493459.1 ENST00000324210.5 ENST00000459747.1	MBNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	muscleblind-like splicing regulator 1
chr19_-_1095330 Show fit	17.91	ENST00000586746.1	POLR2E Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr5_-_79950371 Show fit	17.89	ENST00000511032.1 ENST00000504396.1 ENST00000505337.1	DHFR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dihydrofolate reductase
chrX_-_153718988 Show fit	17.81	ENST00000263512.4 ENST00000393587.4 ENST00000453912.1	SLC10A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 10, member 3
chr11_-_34938039 Show fit	17.80	ENST00000395787.3	APIP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	APAF1 interacting protein
chr7_-_138794081 Show fit	17.77	ENST00000464606.1	ZC3HAV1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CCCH-type, antiviral 1
chr14_-_50154921 Show fit	17.76	ENST00000553805.2 ENST00000554396.1 ENST00000216367.5 ENST00000539565.2	POLE2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (DNA directed), epsilon 2, accessory subunit
chr1_-_63988846 Show fit	17.74	ENST00000283568.8 ENST00000371092.3 ENST00000271002.10	ITGB3BP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin beta 3 binding protein (beta3-endonexin)
chr8_-_63951730 Show fit	17.69	ENST00000260118.6	GGH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr20_+_52824367 Show fit	17.59	ENST00000371419.2	PFDN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prefoldin subunit 4
chr2_-_174828892 Show fit	17.52	ENST00000418194.2	SP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Sp3 transcription factor
chr20_+_23331373 Show fit	17.49	ENST00000254998.2	NXT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NTF2-like export factor 1
chr14_-_102552659 Show fit	17.49	ENST00000441629.2	HSP90AA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr7_-_87849340 Show fit	17.42	ENST00000419179.1 ENST00000265729.2	SRI Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sorcin
chr1_-_246729544 Show fit	17.41	ENST00000544618.1 ENST00000366514.4	TFB2M Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor B2, mitochondrial
chr1_+_54411715 Show fit	17.40	ENST00000371370.3 ENST00000371368.1	LRRC42 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 42
chr3_-_63849571 Show fit	17.37	ENST00000295899.5	THOC7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	THO complex 7 homolog (Drosophila)

View svg image
View png image

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.1	45.3	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
13.9	83.5	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
13.9	41.6	GO:0046080	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
12.6	37.7	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
12.1	36.2	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
11.6	150.4	GO:0000492	box C/D snoRNP assembly(GO:0000492)
11.2	44.6	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
11.1	55.3	GO:0009438	methylglyoxal metabolic process(GO:0009438)
10.8	32.5	GO:0044209	AMP salvage(GO:0044209)
10.2	40.9	GO:0043335	protein unfolding(GO:0043335)
10.0	29.9	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
9.3	37.3	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
9.2	73.9	GO:1903333	negative regulation of protein folding(GO:1903333)
9.0	45.2	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
8.8	26.3	GO:0006738	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
8.7	43.7	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
8.7	52.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
8.4	33.4	GO:0046452	dihydrofolate metabolic process(GO:0046452)
8.2	32.8	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
8.1	24.3	GO:2000653	regulation of genetic imprinting(GO:2000653)
8.1	32.2	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
7.9	23.8	GO:1900195	spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
7.7	31.0	GO:0009202	dTTP biosynthetic process(GO:0006235) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
7.7	23.2	GO:0007113	endomitotic cell cycle(GO:0007113)
7.7	23.0	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
7.5	44.8	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
7.4	29.6	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
7.2	21.7	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
7.2	35.8	GO:0061198	fungiform papilla formation(GO:0061198)
7.1	21.4	GO:0034471	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
7.1	21.2	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
7.0	7.0	GO:0048254	snoRNA localization(GO:0048254)
6.9	48.5	GO:0090204	protein localization to nuclear pore(GO:0090204)
6.8	34.2	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
6.7	20.0	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
6.6	26.3	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
6.4	32.0	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
6.3	19.0	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
6.3	19.0	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
6.3	37.6	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
6.3	6.3	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
6.2	31.1	GO:0048478	replication fork protection(GO:0048478)
6.1	24.3	GO:0090166	Golgi disassembly(GO:0090166)
5.9	17.7	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
5.8	28.8	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
5.7	17.2	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
5.6	16.8	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
5.6	16.7	GO:0006097	glyoxylate cycle(GO:0006097)
5.5	44.1	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
5.4	16.3	GO:1903674	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
5.4	27.0	GO:0097501	stress response to metal ion(GO:0097501)
5.3	16.0	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
5.3	37.1	GO:0000710	meiotic mismatch repair(GO:0000710)
5.2	15.6	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
5.1	15.4	GO:1901873	regulation of post-translational protein modification(GO:1901873)
5.1	35.7	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
5.0	372.5	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
5.0	15.0	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
5.0	14.9	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
4.9	39.6	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
4.9	34.2	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
4.8	19.1	GO:0072683	T cell extravasation(GO:0072683)
4.7	18.9	GO:0046778	modification by virus of host mRNA processing(GO:0046778)
4.7	42.4	GO:0001833	inner cell mass cell proliferation(GO:0001833)
4.6	41.7	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
4.6	101.5	GO:0006465	signal peptide processing(GO:0006465)
4.6	13.7	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
4.5	9.0	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
4.5	8.9	GO:0042256	mature ribosome assembly(GO:0042256)
4.4	48.7	GO:0090168	Golgi reassembly(GO:0090168)
4.4	13.1	GO:0051685	maintenance of ER location(GO:0051685)
4.4	17.4	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
4.3	12.8	GO:1902499	positive regulation of protein autoubiquitination(GO:1902499)
4.2	37.6	GO:0001887	selenium compound metabolic process(GO:0001887)
4.1	20.7	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
4.1	49.2	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
4.0	12.1	GO:1901994	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
4.0	100.3	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
4.0	24.0	GO:0031126	snoRNA 3'-end processing(GO:0031126)
4.0	12.0	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
4.0	15.8	GO:0046104	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
3.9	15.4	GO:2000819	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) regulation of nucleotide-excision repair(GO:2000819)
3.8	49.8	GO:1904869	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
3.8	22.9	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
3.8	11.5	GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
3.8	11.3	GO:0006267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.8	30.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
3.8	22.6	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
3.8	49.0	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
3.7	29.8	GO:0015866	ADP transport(GO:0015866)
3.7	11.2	GO:2000234	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
3.7	26.0	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
3.7	14.8	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
3.7	11.1	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
3.7	25.7	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
3.7	22.0	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
3.6	21.7	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
3.6	46.7	GO:0070986	left/right axis specification(GO:0070986)
3.6	10.7	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
3.5	14.2	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
3.5	10.5	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
3.5	13.9	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
3.4	37.9	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
3.4	34.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
3.3	16.7	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
3.3	19.9	GO:0006177	GMP biosynthetic process(GO:0006177)
3.3	22.8	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
3.3	9.8	GO:0006788	heme oxidation(GO:0006788)
3.2	19.4	GO:0006021	inositol biosynthetic process(GO:0006021)
3.2	22.5	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
3.2	9.6	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)
3.2	51.3	GO:0043248	proteasome assembly(GO:0043248)
3.2	9.6	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
3.2	9.6	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
3.2	70.5	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
3.1	25.2	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
3.1	18.8	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
3.1	31.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
3.1	6.2	GO:2000377	regulation of reactive oxygen species metabolic process(GO:2000377)
3.1	9.3	GO:0002184	cytoplasmic translational termination(GO:0002184)
3.1	46.5	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
3.1	21.5	GO:0090487	toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
3.1	15.4	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
3.0	24.4	GO:0051096	positive regulation of helicase activity(GO:0051096)
3.0	36.5	GO:0000920	cell separation after cytokinesis(GO:0000920)
3.0	88.3	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
3.0	12.1	GO:0006642	triglyceride mobilization(GO:0006642)
3.0	12.0	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
3.0	8.9	GO:0006740	NADPH regeneration(GO:0006740)
3.0	41.3	GO:0000022	mitotic spindle elongation(GO:0000022)
2.9	5.9	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
2.9	17.5	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
2.9	23.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
2.9	17.3	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
2.9	92.1	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
2.8	11.3	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
2.8	187.0	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
2.8	2.8	GO:0030888	regulation of B cell proliferation(GO:0030888)
2.8	30.4	GO:0006089	lactate metabolic process(GO:0006089)
2.7	13.7	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
2.7	13.6	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.7	13.6	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
2.7	10.7	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
2.7	13.4	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
2.7	8.0	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
2.7	16.0	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
2.7	26.6	GO:0042407	cristae formation(GO:0042407)
2.7	8.0	GO:1901297	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
2.7	13.3	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
2.7	18.6	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
2.7	8.0	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
2.6	303.1	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
2.6	23.4	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478)
2.6	10.3	GO:0002317	plasma cell differentiation(GO:0002317)
2.6	23.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.6	17.9	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
2.5	12.7	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
2.5	10.2	GO:0044375	regulation of peroxisome size(GO:0044375)
2.5	7.6	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
2.5	30.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
2.5	7.5	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
2.5	10.0	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.5	17.4	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.5	56.8	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
2.5	2.5	GO:0009441	glycolate metabolic process(GO:0009441)
2.5	9.8	GO:1903826	arginine transmembrane transport(GO:1903826)
2.5	44.2	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
2.4	7.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
2.4	9.6	GO:0090309	maintenance of DNA methylation(GO:0010216) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
2.4	14.4	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
2.4	4.7	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512)
2.4	11.8	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
2.3	28.1	GO:0031468	nuclear envelope reassembly(GO:0031468)
2.3	9.3	GO:1902965	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
2.3	6.9	GO:0016074	snoRNA metabolic process(GO:0016074)
2.3	9.2	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
2.3	11.4	GO:0030047	actin modification(GO:0030047)
2.3	6.8	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
2.3	106.8	GO:0007077	mitotic nuclear envelope disassembly(GO:0007077)
2.3	15.9	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
2.3	2.3	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
2.3	4.5	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
2.3	13.5	GO:1904925	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
2.3	22.5	GO:0015939	pantothenate metabolic process(GO:0015939)
2.2	18.0	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
2.2	11.2	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
2.2	11.1	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
2.2	17.7	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
2.2	6.6	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
2.2	6.6	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
2.2	35.0	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
2.2	13.0	GO:0035709	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.1	115.8	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
2.1	10.7	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
2.1	8.6	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
2.1	6.3	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
2.1	6.3	GO:0009726	detection of endogenous stimulus(GO:0009726)
2.1	2.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
2.1	8.2	GO:0042247	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
2.1	8.2	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
2.1	10.3	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
2.0	6.1	GO:0070668	negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
2.0	8.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
2.0	6.1	GO:1903926	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
2.0	8.0	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
2.0	5.9	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
2.0	4.0	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
2.0	35.3	GO:0042276	error-prone translesion synthesis(GO:0042276)
2.0	7.8	GO:0010815	bradykinin catabolic process(GO:0010815)
1.9	5.8	GO:0046294	formaldehyde catabolic process(GO:0046294)
1.9	42.5	GO:0007080	mitotic metaphase plate congression(GO:0007080)
1.9	9.6	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
1.9	5.7	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
1.9	11.5	GO:1904044	response to aldosterone(GO:1904044)
1.9	13.3	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
1.9	7.6	GO:0046108	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
1.9	9.4	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.9	24.4	GO:0045008	depyrimidination(GO:0045008)
1.9	7.5	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
1.8	1.8	GO:1900110	negative regulation of histone H3-K9 dimethylation(GO:1900110)
1.8	12.9	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.8	5.5	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
1.8	20.2	GO:0051310	metaphase plate congression(GO:0051310)
1.8	14.6	GO:0042262	DNA protection(GO:0042262)
1.8	10.8	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
1.8	5.4	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
1.8	7.2	GO:0097368	histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
1.8	3.5	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
1.8	14.1	GO:0070200	establishment of protein localization to telomere(GO:0070200)
1.8	15.9	GO:0006294	nucleotide-excision repair, preincision complex assembly(GO:0006294)
1.8	8.8	GO:0061738	late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.8	124.4	GO:0045454	cell redox homeostasis(GO:0045454)
1.7	8.7	GO:0019401	alditol biosynthetic process(GO:0019401)
1.7	17.2	GO:1900016	negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
1.7	17.1	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.7	8.5	GO:0009838	abscission(GO:0009838)
1.7	22.0	GO:0007076	mitotic chromosome condensation(GO:0007076)
1.7	13.5	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
1.7	8.4	GO:0006529	asparagine biosynthetic process(GO:0006529)
1.7	8.4	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.7	6.7	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.6	13.2	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.6	13.2	GO:0010608	posttranscriptional regulation of gene expression(GO:0010608)
1.6	6.6	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
1.6	11.4	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
1.6	1.6	GO:0006273	lagging strand elongation(GO:0006273)
1.6	17.5	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.6	19.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
1.6	36.3	GO:0061157	mRNA destabilization(GO:0061157)
1.6	18.9	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
1.6	39.4	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
1.6	12.4	GO:0042182	ketone catabolic process(GO:0042182)
1.6	6.2	GO:0046967	cytosol to ER transport(GO:0046967)
1.5	4.6	GO:1904647	response to rotenone(GO:1904647)
1.5	27.4	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.5	13.7	GO:0090400	stress-induced premature senescence(GO:0090400)
1.5	7.6	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.5	12.0	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.5	11.8	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.5	2.9	GO:0006352	DNA-templated transcription, initiation(GO:0006352)
1.5	1.5	GO:0021539	subthalamus development(GO:0021539)
1.4	7.2	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
1.4	10.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
1.4	64.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
1.4	14.4	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
1.4	7.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
1.4	5.7	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
1.4	5.6	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
1.4	7.0	GO:0034350	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
1.4	15.3	GO:0060576	intestinal epithelial cell development(GO:0060576)
1.4	57.6	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
1.4	15.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
1.4	4.1	GO:0006014	D-ribose metabolic process(GO:0006014)
1.3	25.6	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
1.3	153.8	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
1.3	10.6	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.3	5.2	GO:0031860	telomeric 3' overhang formation(GO:0031860)
1.3	9.2	GO:1900223	positive regulation of beta-amyloid clearance(GO:1900223)
1.3	6.5	GO:0060356	leucine import(GO:0060356)
1.3	34.6	GO:0006301	postreplication repair(GO:0006301)
1.3	3.8	GO:0052027	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.3	7.6	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
1.3	5.0	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
1.3	3.8	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
1.3	6.3	GO:1903751	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
1.2	13.7	GO:0033327	Leydig cell differentiation(GO:0033327)
1.2	9.9	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
1.2	3.6	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
1.2	14.5	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.2	3.6	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
1.2	21.6	GO:0061718	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.2	19.1	GO:0035067	negative regulation of histone acetylation(GO:0035067)
1.2	22.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.1	9.2	GO:0002934	desmosome organization(GO:0002934)
1.1	4.5	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
1.1	10.1	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.1	5.6	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
1.1	12.2	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.1	34.2	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.1	3.3	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.1	13.2	GO:0018206	peptidyl-methionine modification(GO:0018206)
1.1	38.3	GO:0050873	brown fat cell differentiation(GO:0050873)
1.1	3.2	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
1.1	21.5	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
1.1	10.7	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
1.1	10.6	GO:0001731	formation of translation preinitiation complex(GO:0001731)
1.1	9.5	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
1.1	5.3	GO:0075713	establishment of integrated proviral latency(GO:0075713)
1.0	11.5	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
1.0	9.4	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
1.0	4.2	GO:0061289	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.0	21.8	GO:0008334	histone mRNA metabolic process(GO:0008334)
1.0	12.4	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
1.0	16.4	GO:2001205	negative regulation of osteoclast development(GO:2001205)
1.0	1.0	GO:0036512	trimming of terminal mannose on B branch(GO:0036509) trimming of terminal mannose on C branch(GO:0036510) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
1.0	3.0	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
1.0	7.1	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
1.0	8.0	GO:2000210	positive regulation of anoikis(GO:2000210)
1.0	14.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
1.0	4.0	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
1.0	8.0	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.0	4.0	GO:0030242	pexophagy(GO:0030242)
1.0	1.0	GO:0040031	snRNA modification(GO:0040031)
1.0	3.0	GO:0044806	positive regulation of deoxyribonuclease activity(GO:0032077) positive regulation of endodeoxyribonuclease activity(GO:0032079) G-quadruplex DNA unwinding(GO:0044806)
1.0	8.9	GO:0040016	embryonic cleavage(GO:0040016)
1.0	40.4	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.0	2.9	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
1.0	11.7	GO:0007379	segment specification(GO:0007379)
1.0	10.7	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.9	20.6	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.9	2.8	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.9	8.3	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.9	6.3	GO:0030091	protein repair(GO:0030091)
0.9	8.1	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.9	3.6	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.9	1.8	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.9	4.4	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.9	7.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.9	2.7	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.9	2.6	GO:0043318	regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318) insulin catabolic process(GO:1901143)
0.9	3.4	GO:0032506	cytokinetic process(GO:0032506)
0.9	4.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.9	2.6	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.9	22.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.8	18.5	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.8	1.7	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.8	2.5	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.8	6.7	GO:0070327	thyroid hormone transport(GO:0070327)
0.8	6.7	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.8	7.5	GO:1900038	negative regulation of cellular response to hypoxia(GO:1900038)
0.8	18.4	GO:0006825	copper ion transport(GO:0006825)
0.8	4.2	GO:0035811	negative regulation of urine volume(GO:0035811)
0.8	6.5	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.8	14.3	GO:0043486	histone exchange(GO:0043486)
0.8	31.0	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.8	9.5	GO:0050872	white fat cell differentiation(GO:0050872)
0.8	3.9	GO:0007386	compartment pattern specification(GO:0007386)
0.8	6.3	GO:0002021	response to dietary excess(GO:0002021)
0.8	32.5	GO:0090307	mitotic spindle assembly(GO:0090307)
0.8	6.9	GO:0048745	smooth muscle tissue development(GO:0048745)
0.8	7.7	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.8	2.3	GO:0033386	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.8	2.3	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.8	48.8	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.8	2.3	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.7	15.7	GO:0000281	mitotic cytokinesis(GO:0000281)
0.7	14.7	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.7	9.5	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.7	50.4	GO:0051289	protein homotetramerization(GO:0051289)
0.7	58.4	GO:0007062	sister chromatid cohesion(GO:0007062)
0.7	17.9	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
0.7	10.5	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.7	3.5	GO:0061143	alveolar primary septum development(GO:0061143)
0.7	2.1	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.7	11.6	GO:0022904	respiratory electron transport chain(GO:0022904)
0.7	2.7	GO:0060434	bronchus morphogenesis(GO:0060434)
0.7	6.7	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.7	2.7	GO:0034612	response to tumor necrosis factor(GO:0034612)
0.7	4.0	GO:0032042	mitochondrial DNA metabolic process(GO:0032042)
0.7	3.3	GO:0031337	cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.7	2.0	GO:0002232	leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.7	2.0	GO:0036302	atrioventricular canal development(GO:0036302)
0.6	4.5	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.6	1.3	GO:0010041	response to iron(III) ion(GO:0010041)
0.6	13.4	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.6	7.7	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.6	8.2	GO:0006289	nucleotide-excision repair(GO:0006289)
0.6	3.8	GO:0030421	defecation(GO:0030421)
0.6	2.5	GO:0060283	negative regulation of oocyte development(GO:0060283) regulation of oocyte maturation(GO:1900193) negative regulation of oocyte maturation(GO:1900194)
0.6	13.6	GO:0016578	histone deubiquitination(GO:0016578)
0.6	8.6	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.6	2.4	GO:1905123	regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.6	4.2	GO:0006983	ER overload response(GO:0006983)
0.6	35.0	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.6	6.6	GO:0072697	protein localization to cell cortex(GO:0072697) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.6	1.2	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.6	16.7	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.6	1.2	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.6	6.5	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.6	6.5	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.6	9.4	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.6	2.3	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.6	23.9	GO:0035329	hippo signaling(GO:0035329)
0.6	3.4	GO:0061042	vascular wound healing(GO:0061042)
0.6	10.8	GO:0035456	response to interferon-beta(GO:0035456)
0.6	23.7	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.6	3.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.5	4.4	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.5	1.6	GO:0033341	regulation of collagen binding(GO:0033341)
0.5	3.8	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.5	15.7	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.5	13.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.5	3.7	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.5	2.7	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.5	11.0	GO:0070207	protein homotrimerization(GO:0070207)
0.5	3.7	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.5	4.7	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.5	2.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.5	1.0	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.5	6.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.5	1.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.5	8.0	GO:0018345	protein palmitoylation(GO:0018345)
0.5	11.9	GO:0031581	hemidesmosome assembly(GO:0031581)
0.5	35.2	GO:0043488	regulation of mRNA stability(GO:0043488)
0.5	4.9	GO:0015889	cobalamin transport(GO:0015889)
0.5	3.3	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.5	2.3	GO:0071895	odontoblast differentiation(GO:0071895)
0.5	3.7	GO:0051132	NK T cell activation(GO:0051132)
0.5	6.0	GO:0006379	mRNA cleavage(GO:0006379)
0.5	43.8	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.5	1.8	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.5	8.7	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.5	2.7	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.5	9.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.5	3.2	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.4	15.3	GO:0043114	regulation of vascular permeability(GO:0043114)
0.4	6.3	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.4	0.9	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4	2.2	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.4	6.8	GO:0002003	angiotensin maturation(GO:0002003)
0.4	7.8	GO:0006337	nucleosome disassembly(GO:0006337)
0.4	9.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.4	2.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.4	2.4	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.4	5.3	GO:0006012	galactose metabolic process(GO:0006012)
0.4	1.2	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4	3.6	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.4	2.4	GO:0061635	regulation of protein complex stability(GO:0061635)
0.4	43.4	GO:0070268	cornification(GO:0070268)
0.4	2.3	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.4	1.6	GO:0071233	cellular response to leucine(GO:0071233)
0.4	5.4	GO:0009235	cobalamin metabolic process(GO:0009235)
0.4	10.7	GO:1900006	positive regulation of dendrite development(GO:1900006)
0.4	3.0	GO:0030252	growth hormone secretion(GO:0030252)
0.4	0.8	GO:0061511	centriole elongation(GO:0061511)
0.4	1.1	GO:0060373	glycerol-3-phosphate metabolic process(GO:0006072) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.4	1.1	GO:0006550	isoleucine catabolic process(GO:0006550)
0.4	8.8	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.4	15.0	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.4	1.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.4	3.6	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.4	1.4	GO:0007296	vitellogenesis(GO:0007296)
0.4	3.5	GO:0033197	response to vitamin E(GO:0033197)
0.4	5.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.3	5.5	GO:0051145	smooth muscle cell differentiation(GO:0051145)
0.3	4.4	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3	13.9	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.3	16.3	GO:0070988	demethylation(GO:0070988)
0.3	1.3	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3	3.9	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3	29.3	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.3	1.6	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.3	8.6	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.3	2.8	GO:0018344	protein geranylgeranylation(GO:0018344)
0.3	0.3	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.3	0.8	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.3	7.5	GO:0010595	positive regulation of endothelial cell migration(GO:0010595)
0.3	1.7	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.3	1.4	GO:1990791	renal artery morphogenesis(GO:0061441) dorsal root ganglion development(GO:1990791)
0.3	67.7	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.3	1.3	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.3	3.7	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.3	4.5	GO:0016925	protein sumoylation(GO:0016925)
0.3	1.0	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.3	2.9	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.3	4.9	GO:0002643	regulation of tolerance induction(GO:0002643)
0.3	0.8	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.3	13.4	GO:0045333	cellular respiration(GO:0045333)
0.2	4.9	GO:0014823	response to activity(GO:0014823)
0.2	3.4	GO:0071294	cellular response to zinc ion(GO:0071294)
0.2	5.7	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2	2.8	GO:0031424	keratinization(GO:0031424)
0.2	0.9	GO:0038042	dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2	1.4	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.2	5.5	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.2	4.1	GO:0019054	modulation by virus of host process(GO:0019054)
0.2	4.5	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.2	0.9	GO:0050957	equilibrioception(GO:0050957)
0.2	1.8	GO:0015816	glycine transport(GO:0015816)
0.2	1.1	GO:1901018	positive regulation of potassium ion transmembrane transporter activity(GO:1901018)
0.2	4.6	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.2	1.1	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.2	2.5	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.2	1.8	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.2	1.1	GO:0007035	vacuolar acidification(GO:0007035)
0.2	0.6	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.2	5.9	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2	5.7	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
0.2	2.8	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2	2.5	GO:0030011	maintenance of cell polarity(GO:0030011)
0.2	5.2	GO:0001755	neural crest cell migration(GO:0001755)
0.2	5.0	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.2	1.2	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2	3.6	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1	1.1	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1	0.4	GO:0042938	dipeptide transport(GO:0042938)
0.1	0.4	GO:0019417	sulfur oxidation(GO:0019417)
0.1	0.5	GO:0030510	regulation of BMP signaling pathway(GO:0030510)
0.1	8.2	GO:0006901	vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	6.9	GO:0001649	osteoblast differentiation(GO:0001649)
0.1	4.8	GO:0001895	retina homeostasis(GO:0001895)
0.1	0.5	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.1	1.6	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	0.3	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.4	GO:0002739	regulation of cytokine secretion involved in immune response(GO:0002739) positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.1	10.8	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.1	3.4	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.1	4.7	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	2.9	GO:0001960	negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.1	8.5	GO:0006413	translational initiation(GO:0006413)
0.1	0.8	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1	1.1	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715)
0.1	0.4	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.1	5.7	GO:0006968	cellular defense response(GO:0006968)
0.1	0.4	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.1	0.4	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.4	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	2.8	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	2.1	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.1	0.5	GO:0014041	regulation of neuron maturation(GO:0014041)
0.1	0.4	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.1	0.3	GO:0019827	stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.1	1.0	GO:0007409	axonogenesis(GO:0007409)
0.1	2.5	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.1	0.4	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1	1.2	GO:0051865	protein autoubiquitination(GO:0051865)
0.1	4.7	GO:0030183	B cell differentiation(GO:0030183)
0.1	0.9	GO:0060561	apoptotic process involved in morphogenesis(GO:0060561)
0.1	1.1	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1	1.6	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	1.1	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	1.1	GO:0032392	DNA geometric change(GO:0032392)
0.0	0.2	GO:0006554	lysine catabolic process(GO:0006554)
0.0	0.3	GO:0030307	positive regulation of cell growth(GO:0030307)
0.0	0.7	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.6	GO:0046889	positive regulation of lipid biosynthetic process(GO:0046889)
0.0	1.0	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.1	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	1.8	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.3	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.4	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.2	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.4	GO:0097502	mannosylation(GO:0097502)
0.0	1.2	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	0.5	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.5	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0	1.0	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.2	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.1	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.4	82.2	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
15.1	45.3	GO:0033597	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
14.5	101.5	GO:0005787	signal peptidase complex(GO:0005787)
13.4	106.9	GO:0070761	pre-snoRNP complex(GO:0070761)
13.2	65.9	GO:0097149	centralspindlin complex(GO:0097149)
11.3	11.3	GO:0031261	DNA replication preinitiation complex(GO:0031261)
11.0	44.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
10.9	43.6	GO:0031510	SUMO activating enzyme complex(GO:0031510)
10.6	42.4	GO:0000811	GINS complex(GO:0000811)
10.5	282.9	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
8.8	44.0	GO:0000408	EKC/KEOPS complex(GO:0000408)
8.5	34.1	GO:1990423	RZZ complex(GO:1990423)
7.8	39.0	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
7.7	30.6	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
7.3	29.4	GO:0071001	U4/U6 snRNP(GO:0071001)
7.3	73.2	GO:0070938	contractile ring(GO:0070938)
7.1	21.4	GO:0030689	Noc complex(GO:0030689)
7.1	85.0	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
7.1	35.3	GO:0045323	interleukin-1 receptor complex(GO:0045323)
7.0	28.1	GO:1990730	VCP-NSFL1C complex(GO:1990730)
7.0	7.0	GO:0005687	U4 snRNP(GO:0005687)
6.5	39.2	GO:0071817	MMXD complex(GO:0071817)
5.9	52.7	GO:0072546	ER membrane protein complex(GO:0072546)
5.7	22.9	GO:0031417	NatC complex(GO:0031417)
5.6	33.5	GO:0005683	U7 snRNP(GO:0005683)
5.5	22.1	GO:0032301	MutSalpha complex(GO:0032301)
5.5	16.4	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942) Ndc80 complex(GO:0031262)
5.5	43.7	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
5.4	43.4	GO:0097255	R2TP complex(GO:0097255)
5.4	21.7	GO:1990246	uniplex complex(GO:1990246)
5.2	31.1	GO:0031298	replication fork protection complex(GO:0031298)
5.0	30.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
4.8	14.4	GO:0043159	acrosomal matrix(GO:0043159)
4.7	37.7	GO:1990111	spermatoproteasome complex(GO:1990111)
4.7	28.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
4.6	37.2	GO:0070552	BRISC complex(GO:0070552)
4.6	32.2	GO:0005956	protein kinase CK2 complex(GO:0005956)
4.5	13.6	GO:0005960	glycine cleavage complex(GO:0005960)
4.5	13.6	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
4.4	17.7	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
4.4	21.9	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
4.3	17.1	GO:0001405	presequence translocase-associated import motor(GO:0001405)
4.2	75.8	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
4.1	20.7	GO:0043564	Ku70:Ku80 complex(GO:0043564)
4.0	63.4	GO:0031080	nuclear pore outer ring(GO:0031080)
3.9	11.7	GO:0097447	dendritic tree(GO:0097447)
3.8	22.8	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
3.7	22.3	GO:0001740	Barr body(GO:0001740)
3.6	65.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
3.5	20.9	GO:0072589	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
3.4	10.3	GO:0034680	integrin alpha1-beta1 complex(GO:0034665) integrin alpha3-beta1 complex(GO:0034667) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680)
3.4	37.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
3.4	6.7	GO:0070939	Dsl1p complex(GO:0070939)
3.3	3.3	GO:1902636	kinociliary basal body(GO:1902636)
3.2	32.4	GO:0030015	CCR4-NOT core complex(GO:0030015)
3.2	19.3	GO:0070545	PeBoW complex(GO:0070545)
3.1	22.0	GO:1990635	proximal dendrite(GO:1990635)
3.1	12.5	GO:0005828	kinetochore microtubule(GO:0005828)
3.1	9.3	GO:0018444	translation release factor complex(GO:0018444)
3.1	18.6	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
3.0	6.1	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
3.0	21.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
3.0	12.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
3.0	23.8	GO:0032133	chromosome passenger complex(GO:0032133)
2.9	41.1	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
2.9	29.3	GO:0000796	condensin complex(GO:0000796)
2.8	68.4	GO:0030687	preribosome, large subunit precursor(GO:0030687)
2.8	22.6	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.8	11.3	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
2.8	11.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
2.8	74.7	GO:0000178	exosome (RNase complex)(GO:0000178)
2.7	167.3	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
2.7	32.5	GO:0090543	Flemming body(GO:0090543)
2.7	45.3	GO:0044613	nuclear pore central transport channel(GO:0044613)
2.6	34.4	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
2.6	18.5	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
2.6	10.6	GO:0033186	CAF-1 complex(GO:0033186)
2.6	21.0	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
2.5	15.2	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
2.5	48.0	GO:0005885	Arp2/3 protein complex(GO:0005885)
2.5	35.3	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
2.5	47.9	GO:0005832	chaperonin-containing T-complex(GO:0005832)
2.5	12.6	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
2.5	17.6	GO:0016272	prefoldin complex(GO:0016272)
2.5	20.0	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
2.5	17.4	GO:0044326	dendritic spine neck(GO:0044326)
2.4	21.8	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
2.4	29.0	GO:0001741	XY body(GO:0001741)
2.4	26.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
2.4	26.1	GO:0005688	U6 snRNP(GO:0005688)
2.4	253.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
2.3	13.9	GO:0008537	proteasome activator complex(GO:0008537)
2.3	32.1	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
2.3	38.6	GO:0005686	U2 snRNP(GO:0005686)
2.2	15.6	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
2.2	15.5	GO:0061617	MICOS complex(GO:0061617)
2.2	28.8	GO:0042555	MCM complex(GO:0042555)
2.2	8.6	GO:0005839	proteasome core complex(GO:0005839)
2.2	30.2	GO:0005662	DNA replication factor A complex(GO:0005662)
2.1	32.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
2.1	100.8	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
2.1	17.0	GO:0031931	TORC1 complex(GO:0031931)
2.1	4.2	GO:0045259	proton-transporting ATP synthase complex(GO:0045259)
2.1	4.2	GO:0097454	Schwann cell microvillus(GO:0097454)
2.1	6.3	GO:0045180	basal cortex(GO:0045180)
2.0	6.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
2.0	83.8	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
2.0	34.4	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
2.0	10.1	GO:0031010	ISWI-type complex(GO:0031010)
2.0	7.9	GO:0070876	SOSS complex(GO:0070876)
2.0	35.5	GO:0097342	ripoptosome(GO:0097342)
1.9	39.6	GO:0035098	ESC/E(Z) complex(GO:0035098)
1.9	9.3	GO:0035578	azurophil granule lumen(GO:0035578)
1.9	16.7	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.8	34.3	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
1.8	21.2	GO:0042405	nuclear inclusion body(GO:0042405)
1.7	33.0	GO:0030686	90S preribosome(GO:0030686)
1.7	5.2	GO:0097431	mitotic spindle pole(GO:0097431)
1.7	12.0	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
1.7	10.2	GO:0031088	platelet dense granule membrane(GO:0031088)
1.7	142.4	GO:0000777	condensed chromosome kinetochore(GO:0000777)
1.7	50.7	GO:0005680	anaphase-promoting complex(GO:0005680)
1.7	31.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
1.6	8.2	GO:0042643	actomyosin, actin portion(GO:0042643)
1.6	6.5	GO:0032044	DSIF complex(GO:0032044)
1.6	9.5	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
1.6	15.8	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
1.6	4.7	GO:0033565	ESCRT-0 complex(GO:0033565)
1.6	15.5	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
1.5	64.2	GO:0000502	proteasome complex(GO:0000502)
1.5	6.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.5	16.3	GO:0016602	CCAAT-binding factor complex(GO:0016602)
1.5	31.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.5	19.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
1.4	15.7	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
1.4	2.8	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
1.4	30.2	GO:0030992	intraciliary transport particle B(GO:0030992)
1.3	14.5	GO:0000124	SAGA complex(GO:0000124)
1.3	7.8	GO:0032311	angiogenin-PRI complex(GO:0032311)
1.3	5.2	GO:0043260	laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
1.3	3.8	GO:0005726	perichromatin fibrils(GO:0005726)
1.3	33.8	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
1.3	8.8	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
1.3	6.3	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
1.2	34.1	GO:0070469	respiratory chain(GO:0070469)
1.2	9.3	GO:0051286	cell tip(GO:0051286)
1.2	4.6	GO:0055087	Ski complex(GO:0055087)
1.2	10.4	GO:0033588	Elongator holoenzyme complex(GO:0033588)
1.1	196.9	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
1.1	13.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
1.1	13.4	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.1	35.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
1.1	8.8	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
1.1	7.5	GO:0071203	WASH complex(GO:0071203)
1.0	12.5	GO:0000815	ESCRT III complex(GO:0000815)
1.0	6.2	GO:0042824	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
1.0	8.3	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.0	1.0	GO:0000938	GARP complex(GO:0000938)
1.0	6.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.0	9.1	GO:0010369	chromocenter(GO:0010369)
1.0	3.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
1.0	11.9	GO:0001673	male germ cell nucleus(GO:0001673)
1.0	9.6	GO:0005721	pericentric heterochromatin(GO:0005721)
1.0	15.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.9	3.7	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.9	10.3	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.9	2.8	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.9	2.8	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.9	49.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.9	4.6	GO:0032389	MutLalpha complex(GO:0032389)
0.9	1.8	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.9	18.0	GO:0005801	cis-Golgi network(GO:0005801)
0.9	14.1	GO:0005720	nuclear heterochromatin(GO:0005720)
0.9	38.6	GO:0008180	COP9 signalosome(GO:0008180)
0.9	1.7	GO:0031089	platelet dense granule lumen(GO:0031089) platelet dense granule(GO:0042827)
0.8	4.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.8	6.7	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.8	8.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.8	4.9	GO:0030014	CCR4-NOT complex(GO:0030014)
0.8	2.4	GO:0031213	RSF complex(GO:0031213)
0.8	13.5	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.8	10.9	GO:0005783	endoplasmic reticulum(GO:0005783)
0.7	9.7	GO:0097470	ribbon synapse(GO:0097470)
0.7	14.0	GO:0005844	polysome(GO:0005844)
0.7	98.6	GO:0030496	midbody(GO:0030496)
0.7	13.8	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.7	7.6	GO:0044666	MLL3/4 complex(GO:0044666)
0.7	20.2	GO:0030057	desmosome(GO:0030057)
0.7	4.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.7	1.3	GO:0071159	NF-kappaB complex(GO:0071159)
0.7	88.9	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.6	39.7	GO:0005637	nuclear inner membrane(GO:0005637)
0.6	4.4	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.6	7.5	GO:0032433	filopodium tip(GO:0032433)
0.6	2.5	GO:0031673	H zone(GO:0031673)
0.6	4.9	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.6	6.7	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.6	5.4	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.6	1.8	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.6	17.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.6	37.5	GO:0005643	nuclear pore(GO:0005643)
0.6	7.8	GO:0000118	histone deacetylase complex(GO:0000118)
0.6	7.3	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.6	3.9	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.6	6.1	GO:0005614	interstitial matrix(GO:0005614)
0.6	22.8	GO:0045095	keratin filament(GO:0045095)
0.6	197.8	GO:0005759	mitochondrial matrix(GO:0005759)
0.5	14.7	GO:0035869	ciliary transition zone(GO:0035869)
0.5	22.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.5	33.2	GO:0045178	basal part of cell(GO:0045178)
0.5	10.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.5	20.3	GO:0002102	podosome(GO:0002102)
0.5	2.6	GO:0032449	CBM complex(GO:0032449)
0.5	26.4	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.5	1.9	GO:0070695	FHF complex(GO:0070695)
0.5	5.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.5	5.7	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.5	8.6	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.5	2.8	GO:0000242	pericentriolar material(GO:0000242)
0.4	40.3	GO:0005681	spliceosomal complex(GO:0005681)
0.4	7.2	GO:0036020	endolysosome membrane(GO:0036020)
0.4	24.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4	2.3	GO:0071438	invadopodium membrane(GO:0071438)
0.4	6.8	GO:0030904	retromer complex(GO:0030904)
0.4	9.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.4	15.7	GO:0055038	recycling endosome membrane(GO:0055038)
0.3	6.3	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.3	2.7	GO:0097546	ciliary base(GO:0097546)
0.3	14.7	GO:0001725	stress fiber(GO:0001725) actin filament bundle(GO:0032432) contractile actin filament bundle(GO:0097517)
0.3	4.8	GO:0005814	centriole(GO:0005814)
0.3	7.4	GO:0000776	kinetochore(GO:0000776)
0.3	1.6	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.3	4.9	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.3	3.8	GO:0031209	SCAR complex(GO:0031209)
0.3	17.7	GO:0005811	lipid particle(GO:0005811)
0.3	1.4	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3	13.7	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.3	5.2	GO:0030125	clathrin vesicle coat(GO:0030125)
0.3	2.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.3	100.0	GO:0016607	nuclear speck(GO:0016607)
0.3	2.3	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.3	13.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	26.1	GO:0005923	bicellular tight junction(GO:0005923)
0.2	11.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	4.6	GO:1902494	catalytic complex(GO:1902494)
0.2	0.2	GO:0032302	MutSbeta complex(GO:0032302)
0.2	32.1	GO:0042383	sarcolemma(GO:0042383)
0.2	1.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	0.8	GO:0030914	STAGA complex(GO:0030914)
0.2	0.9	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2	6.3	GO:0043034	costamere(GO:0043034)
0.2	1.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.2	16.4	GO:0016605	PML body(GO:0016605)
0.2	5.5	GO:0042581	specific granule(GO:0042581)
0.2	1.9	GO:0030008	TRAPP complex(GO:0030008)
0.2	9.7	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.2	1.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	1.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	5.2	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	14.8	GO:0030018	Z disc(GO:0030018)
0.1	0.9	GO:1903440	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1	2.4	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	16.0	GO:0005795	Golgi stack(GO:0005795)
0.1	1.4	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	1.3	GO:0017119	Golgi transport complex(GO:0017119)
0.1	6.2	GO:0000793	condensed chromosome(GO:0000793)
0.1	2.7	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	2.2	GO:0005802	trans-Golgi network(GO:0005802)
0.1	4.4	GO:0043202	lysosomal lumen(GO:0043202)
0.1	0.7	GO:0070852	cell body fiber(GO:0070852)
0.1	2.6	GO:0035580	specific granule lumen(GO:0035580)
0.1	0.3	GO:0001652	granular component(GO:0001652)
0.1	2.0	GO:0000775	chromosome, centromeric region(GO:0000775)
0.1	1.8	GO:0071564	npBAF complex(GO:0071564)
0.1	1.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	0.5	GO:0032039	integrator complex(GO:0032039)
0.1	18.5	GO:0005635	nuclear envelope(GO:0005635)
0.1	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701) junctional membrane complex(GO:0030314)
0.1	0.3	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.1	3.3	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.1	0.4	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.1	1.2	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.1	0.3	GO:0005675	core TFIIH complex(GO:0000439) holo TFIIH complex(GO:0005675)
0.1	0.4	GO:0097225	sperm midpiece(GO:0097225)
0.1	1.7	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.3	GO:0031430	M band(GO:0031430)
0.0	4.2	GO:0005884	actin filament(GO:0005884)
0.0	0.9	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.4	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:0031932	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0	0.9	GO:0005871	kinesin complex(GO:0005871)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0000792	heterochromatin(GO:0000792)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.9	41.6	GO:0004170	dUTP diphosphatase activity(GO:0004170)
13.6	54.3	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
13.0	52.0	GO:0004743	pyruvate kinase activity(GO:0004743)
12.1	36.2	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
11.0	44.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
10.7	85.5	GO:0044388	small protein activating enzyme binding(GO:0044388)
10.1	30.3	GO:0098626	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
10.0	29.9	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
9.9	39.5	GO:0002060	purine nucleobase binding(GO:0002060)
9.6	67.1	GO:0047134	protein-disulfide reductase activity(GO:0047134)
9.5	37.9	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
9.2	27.5	GO:0010698	acetyltransferase activator activity(GO:0010698)
8.7	43.7	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
8.3	25.0	GO:0034511	U3 snoRNA binding(GO:0034511)
7.7	30.6	GO:0000104	succinate dehydrogenase activity(GO:0000104)
7.6	22.8	GO:0017130	poly(C) RNA binding(GO:0017130)
7.2	43.4	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
7.2	21.7	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
7.1	21.2	GO:0098770	FBXO family protein binding(GO:0098770)
6.6	26.4	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
6.5	45.8	GO:0030620	U2 snRNA binding(GO:0030620)
6.5	90.8	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
6.1	18.4	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
6.1	18.2	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
6.0	84.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
6.0	18.0	GO:0001069	regulatory region RNA binding(GO:0001069)
5.8	69.7	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
5.7	40.2	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
5.6	11.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
5.6	16.7	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
5.5	22.1	GO:0032143	single thymine insertion binding(GO:0032143)
5.4	21.6	GO:0005046	KDEL sequence binding(GO:0005046)
5.4	26.9	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
5.3	16.0	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
5.3	15.9	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
5.3	15.8	GO:0004797	thymidine kinase activity(GO:0004797)
5.2	15.6	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
5.2	36.3	GO:0030621	U4 snRNA binding(GO:0030621)
5.1	45.8	GO:0035174	histone serine kinase activity(GO:0035174)
5.0	25.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
5.0	10.1	GO:0016531	copper chaperone activity(GO:0016531)
5.0	15.0	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
4.9	34.3	GO:1990226	histone methyltransferase binding(GO:1990226)
4.9	34.2	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
4.8	144.4	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
4.7	18.9	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
4.7	37.8	GO:1990446	U1 snRNP binding(GO:1990446)
4.7	14.1	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
4.6	9.3	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
4.6	36.9	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
4.5	22.3	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
4.5	22.3	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
4.4	13.2	GO:0032767	copper-dependent protein binding(GO:0032767)
4.4	21.8	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
4.3	17.3	GO:0071987	WD40-repeat domain binding(GO:0071987)
4.2	89.2	GO:0035173	histone kinase activity(GO:0035173)
4.2	75.8	GO:0001054	RNA polymerase I activity(GO:0001054)
4.2	12.6	GO:0016672	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
4.1	40.9	GO:0030911	TPR domain binding(GO:0030911)
4.0	27.7	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
3.9	11.7	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
3.8	49.9	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
3.8	15.1	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
3.8	22.6	GO:0000400	four-way junction DNA binding(GO:0000400)
3.7	11.2	GO:0035529	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
3.7	14.9	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
3.7	14.9	GO:0005346	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
3.7	22.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
3.6	14.5	GO:0004074	biliverdin reductase activity(GO:0004074)
3.6	25.3	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
3.6	10.7	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
3.5	10.6	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
3.5	10.6	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
3.5	17.6	GO:0008536	Ran GTPase binding(GO:0008536)
3.5	10.5	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
3.5	20.9	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
3.5	24.3	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
3.4	20.6	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
3.4	13.7	GO:0001512	dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
3.4	13.6	GO:0004047	aminomethyltransferase activity(GO:0004047)
3.4	105.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
3.4	13.6	GO:0036033	mediator complex binding(GO:0036033)
3.4	97.9	GO:0017056	structural constituent of nuclear pore(GO:0017056)
3.3	6.7	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
3.3	36.7	GO:0019869	chloride channel inhibitor activity(GO:0019869)
3.3	6.6	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
3.3	9.9	GO:0070260	tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
3.3	52.2	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
3.3	172.6	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
3.3	9.8	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
3.2	25.8	GO:0008312	7S RNA binding(GO:0008312)
3.2	9.6	GO:0000773	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
3.2	41.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
3.1	6.3	GO:0043398	HLH domain binding(GO:0043398)
3.1	34.5	GO:0017128	phospholipid scramblase activity(GO:0017128)
3.1	12.5	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
3.1	137.9	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
3.1	18.8	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
3.1	34.1	GO:0001222	transcription corepressor binding(GO:0001222)
3.1	18.6	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
3.1	15.4	GO:0000405	bubble DNA binding(GO:0000405)
3.0	33.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
3.0	18.0	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
3.0	41.7	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
3.0	20.7	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.9	17.5	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.9	28.8	GO:0031386	protein tag(GO:0031386)
2.8	22.7	GO:0005049	nuclear export signal receptor activity(GO:0005049)
2.8	28.2	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
2.8	16.7	GO:0003998	acylphosphatase activity(GO:0003998)
2.8	24.8	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
2.7	16.3	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
2.7	8.1	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
2.7	10.7	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
2.7	29.4	GO:0015266	protein channel activity(GO:0015266)
2.7	13.4	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
2.7	8.0	GO:0000150	recombinase activity(GO:0000150)
2.6	10.6	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
2.6	10.5	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
2.6	537.5	GO:0003735	structural constituent of ribosome(GO:0003735)
2.6	7.8	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.6	28.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
2.5	10.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
2.5	7.5	GO:0048030	disaccharide binding(GO:0048030)
2.5	7.4	GO:0004756	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
2.5	9.8	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
2.4	7.3	GO:0044547	DNA topoisomerase binding(GO:0044547)
2.4	65.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
2.4	21.8	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
2.4	9.5	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
2.4	49.7	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
2.3	14.1	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
2.3	11.6	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
2.3	11.4	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
2.3	9.1	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
2.3	31.6	GO:0016018	cyclosporin A binding(GO:0016018)
2.2	11.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
2.2	17.4	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
2.2	13.0	GO:0023025	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
2.1	8.6	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
2.1	32.0	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
2.1	8.5	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
2.1	19.1	GO:0035877	death effector domain binding(GO:0035877)
2.1	10.6	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.1	14.7	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.1	8.3	GO:0035473	lipase binding(GO:0035473)
2.1	20.8	GO:0019784	NEDD8-specific protease activity(GO:0019784)
2.1	10.3	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
2.0	8.1	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.0	10.0	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
2.0	13.9	GO:0061133	endopeptidase activator activity(GO:0061133)
2.0	5.9	GO:0070404	NADH binding(GO:0070404)
1.9	5.8	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
1.9	22.9	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
1.9	24.6	GO:0030515	snoRNA binding(GO:0030515)
1.9	7.6	GO:0004850	uridine phosphorylase activity(GO:0004850)
1.9	13.2	GO:0050815	phosphoserine binding(GO:0050815)
1.9	24.4	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
1.9	5.6	GO:0098519	polynucleotide phosphatase activity(GO:0098518) nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.9	9.3	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.8	5.5	GO:0070362	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
1.8	5.5	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
1.8	11.0	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.8	1.8	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
1.8	5.4	GO:0004832	valine-tRNA ligase activity(GO:0004832)
1.8	5.3	GO:0004488	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
1.8	8.8	GO:1990254	keratin filament binding(GO:1990254)
1.8	5.3	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
1.8	12.3	GO:0070087	chromo shadow domain binding(GO:0070087)
1.7	29.0	GO:0008266	poly(U) RNA binding(GO:0008266)
1.7	10.2	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
1.7	5.0	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.6	9.8	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
1.6	4.9	GO:0015235	cobalamin transporter activity(GO:0015235)
1.6	1.6	GO:0019992	diacylglycerol binding(GO:0019992)
1.6	9.6	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.6	6.4	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
1.6	29.9	GO:0070628	proteasome binding(GO:0070628)
1.6	12.5	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
1.5	1.5	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.5	16.7	GO:0019206	nucleoside kinase activity(GO:0019206)
1.5	7.5	GO:0016403	dimethylargininase activity(GO:0016403)
1.5	130.6	GO:0003697	single-stranded DNA binding(GO:0003697)
1.5	4.5	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.5	10.3	GO:0004017	adenylate kinase activity(GO:0004017)
1.5	8.8	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
1.5	26.2	GO:0070182	DNA polymerase binding(GO:0070182)
1.5	16.0	GO:0017070	U6 snRNA binding(GO:0017070)
1.4	15.9	GO:0051430	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.4	11.4	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.4	4.2	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
1.4	9.6	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
1.4	6.8	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
1.4	8.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
1.3	27.0	GO:0000339	RNA cap binding(GO:0000339)
1.3	6.7	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.3	8.0	GO:0017018	myosin phosphatase activity(GO:0017018)
1.3	13.3	GO:0070034	telomerase RNA binding(GO:0070034)
1.3	18.6	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
1.3	4.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.3	14.5	GO:0008641	small protein activating enzyme activity(GO:0008641)
1.3	2.6	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
1.3	35.0	GO:0043015	gamma-tubulin binding(GO:0043015)
1.3	68.6	GO:0019894	kinesin binding(GO:0019894)
1.3	10.3	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
1.3	6.4	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
1.3	22.8	GO:0035497	cAMP response element binding(GO:0035497)
1.3	12.5	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
1.3	51.3	GO:0031492	nucleosomal DNA binding(GO:0031492)
1.2	3.5	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
1.1	9.1	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
1.1	5.6	GO:0097016	L27 domain binding(GO:0097016)
1.1	3.3	GO:0070025	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
1.1	19.7	GO:0070403	NAD+ binding(GO:0070403)
1.1	69.8	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
1.1	2.1	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
1.1	6.4	GO:0050733	RS domain binding(GO:0050733)
1.1	64.6	GO:0070063	RNA polymerase binding(GO:0070063)
1.0	6.2	GO:0023029	MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
1.0	14.4	GO:0019855	calcium channel inhibitor activity(GO:0019855)
1.0	39.0	GO:0019201	guanylate kinase activity(GO:0004385) nucleotide kinase activity(GO:0019201)
1.0	1.0	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
1.0	23.0	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.0	3.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
1.0	16.7	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.0	2.9	GO:0036080	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
1.0	3.9	GO:0008410	CoA-transferase activity(GO:0008410)
1.0	98.2	GO:0043130	ubiquitin binding(GO:0043130)
0.9	15.1	GO:0008143	poly(A) binding(GO:0008143)
0.9	3.7	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.9	9.2	GO:0048156	tau protein binding(GO:0048156)
0.9	9.2	GO:0045545	syndecan binding(GO:0045545)
0.9	105.6	GO:0051082	unfolded protein binding(GO:0051082)
0.9	16.8	GO:0097602	cullin family protein binding(GO:0097602)
0.9	11.4	GO:0050786	RAGE receptor binding(GO:0050786)
0.9	3.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.9	11.4	GO:0019843	rRNA binding(GO:0019843)
0.9	6.0	GO:0001727	lipid kinase activity(GO:0001727)
0.8	3.4	GO:0004348	glucosylceramidase activity(GO:0004348)
0.8	17.7	GO:0008242	omega peptidase activity(GO:0008242)
0.8	6.7	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.8	10.8	GO:0045294	alpha-catenin binding(GO:0045294)
0.8	6.6	GO:0042731	PH domain binding(GO:0042731)
0.8	2.5	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.8	8.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.8	4.9	GO:0035613	RNA stem-loop binding(GO:0035613)
0.8	7.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.8	12.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.8	16.0	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.8	12.8	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.8	10.2	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.8	3.9	GO:0097322	7SK snRNA binding(GO:0097322)
0.8	21.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.8	7.8	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.8	54.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.8	2.3	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.8	30.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.8	15.9	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.8	13.5	GO:0044548	S100 protein binding(GO:0044548)
0.7	3.7	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.7	8.1	GO:0008432	JUN kinase binding(GO:0008432)
0.7	14.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.7	23.6	GO:0043531	ADP binding(GO:0043531)
0.7	34.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.7	3.5	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.7	28.1	GO:0004407	histone deacetylase activity(GO:0004407)
0.7	19.4	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.7	16.4	GO:0005123	death receptor binding(GO:0005123)
0.7	17.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.7	4.7	GO:0004046	aminoacylase activity(GO:0004046)
0.7	2.0	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.7	4.7	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.7	2.6	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.7	6.5	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.6	7.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.6	9.7	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.6	8.7	GO:0043495	protein anchor(GO:0043495)
0.6	8.5	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6	7.2	GO:0008301	DNA binding, bending(GO:0008301)
0.6	25.5	GO:0004386	helicase activity(GO:0004386)
0.5	4.4	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.5	13.0	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.5	3.2	GO:0045569	TRAIL binding(GO:0045569)
0.5	3.6	GO:0016421	CoA carboxylase activity(GO:0016421)
0.5	17.6	GO:0032451	demethylase activity(GO:0032451)
0.5	7.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.5	8.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.5	2.3	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.5	18.0	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.4	3.6	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.4	5.8	GO:0003688	DNA replication origin binding(GO:0003688)
0.4	2.2	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.4	10.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.4	5.5	GO:0009881	photoreceptor activity(GO:0009881)
0.4	10.1	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.4	6.6	GO:0004697	protein kinase C activity(GO:0004697)
0.4	7.0	GO:0008483	transaminase activity(GO:0008483)
0.4	56.0	GO:0044325	ion channel binding(GO:0044325)
0.4	10.7	GO:0051059	NF-kappaB binding(GO:0051059)
0.4	5.3	GO:0004985	opioid receptor activity(GO:0004985)
0.4	11.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.4	3.6	GO:0005000	vasopressin receptor activity(GO:0005000)
0.4	5.6	GO:0032036	myosin heavy chain binding(GO:0032036)
0.4	2.0	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.4	1.6	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4	29.9	GO:0003777	microtubule motor activity(GO:0003777)
0.4	14.0	GO:0005080	protein kinase C binding(GO:0005080)
0.4	14.8	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.4	7.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.4	2.3	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.4	39.3	GO:0047485	protein N-terminus binding(GO:0047485)
0.4	7.3	GO:0005537	mannose binding(GO:0005537)
0.4	2.6	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4	6.6	GO:0070064	proline-rich region binding(GO:0070064)
0.4	2.9	GO:0045159	myosin II binding(GO:0045159)
0.4	3.9	GO:0035198	miRNA binding(GO:0035198)
0.4	18.7	GO:0003743	translation initiation factor activity(GO:0003743)
0.4	59.6	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.3	13.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.3	1.4	GO:0016417	fatty acid synthase activity(GO:0004312) S-acyltransferase activity(GO:0016417)
0.3	2.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.3	8.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.3	6.2	GO:0030331	estrogen receptor binding(GO:0030331)
0.3	6.5	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.3	1.0	GO:0015926	glucosidase activity(GO:0015926)
0.3	3.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3	6.0	GO:0019239	deaminase activity(GO:0019239)
0.3	3.6	GO:1990459	transferrin receptor binding(GO:1990459)
0.3	1.8	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.3	4.7	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.3	13.7	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.3	5.7	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.3	29.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.3	7.0	GO:0042169	SH2 domain binding(GO:0042169)
0.3	1.1	GO:0004966	galanin receptor activity(GO:0004966)
0.3	9.2	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.3	3.5	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.3	2.6	GO:0043621	protein self-association(GO:0043621)
0.3	0.8	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.3	80.7	GO:0045296	cadherin binding(GO:0045296)
0.3	1.8	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.2	1.2	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.2	0.2	GO:0005310	dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.2	4.2	GO:0051400	BH domain binding(GO:0051400)
0.2	1.5	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2	8.9	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.2	5.3	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.2	0.9	GO:0004948	calcitonin receptor activity(GO:0004948)
0.2	3.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.2	2.6	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.2	5.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.2	1.5	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2	2.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.2	3.4	GO:0070566	adenylyltransferase activity(GO:0070566)
0.2	2.8	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	1.0	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.2	4.2	GO:0004871	signal transducer activity(GO:0004871)
0.2	1.4	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	6.4	GO:0032947	protein complex scaffold(GO:0032947)
0.1	7.0	GO:0016836	hydro-lyase activity(GO:0016836)
0.1	1.3	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	1.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	3.5	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1	1.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	1.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	8.6	GO:0051117	ATPase binding(GO:0051117)
0.1	9.4	GO:0030165	PDZ domain binding(GO:0030165)
0.1	108.6	GO:0003723	RNA binding(GO:0003723)
0.1	2.6	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1	1.7	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	1.3	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	13.2	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	9.1	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.1	3.5	GO:0051183	vitamin transporter activity(GO:0051183)
0.1	1.0	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.8	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	1.2	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.1	1.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	1.5	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	1.4	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	1.6	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.1	1.0	GO:0004177	aminopeptidase activity(GO:0004177)
0.1	2.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.5	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.2	GO:1901611	phosphatidylglycerol binding(GO:1901611)
0.0	0.3	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.6	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	3.0	GO:0008236	serine-type peptidase activity(GO:0008236)
0.0	0.7	GO:0008565	protein transporter activity(GO:0008565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.3	88.7	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
3.0	83.1	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
2.9	149.9	PID MYC PATHWAY	C-MYC pathway
2.9	34.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
2.1	122.5	PID PLK1 PATHWAY	PLK1 signaling events
2.1	100.9	PID ATR PATHWAY	ATR signaling pathway
2.0	4.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
2.0	229.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
1.6	84.8	PID AURORA B PATHWAY	Aurora B signaling
1.4	6.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
1.3	121.9	PID E2F PATHWAY	E2F transcription factor network
1.2	17.5	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.1	18.0	PID TRAIL PATHWAY	TRAIL signaling pathway
1.1	34.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
1.0	6.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
1.0	51.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.9	17.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.9	11.9	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.8	31.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.8	42.8	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.7	16.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.7	51.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.7	47.8	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.7	13.7	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.6	57.4	PID P73PATHWAY	p73 transcription factor network
0.6	8.8	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.6	24.7	PID P53 REGULATION PATHWAY	p53 pathway
0.6	56.2	PID CMYB PATHWAY	C-MYB transcription factor network
0.6	8.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.6	40.5	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.6	10.3	PID FOXO PATHWAY	FoxO family signaling
0.6	24.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.6	23.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.5	10.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.5	19.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.5	38.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.5	2.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.5	7.6	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5	27.4	PID AP1 PATHWAY	AP-1 transcription factor network
0.5	47.2	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.5	8.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.4	3.5	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.4	11.8	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.4	6.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.4	7.3	PID ARF 3PATHWAY	Arf1 pathway
0.4	10.1	PID RHOA PATHWAY	RhoA signaling pathway
0.4	4.4	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.4	16.8	PID LKB1 PATHWAY	LKB1 signaling events
0.3	13.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.3	19.0	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.3	5.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.3	12.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.3	5.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.3	12.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.3	10.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.2	4.1	PID RAS PATHWAY	Regulation of Ras family activation
0.2	0.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.2	5.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.2	2.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	10.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	3.9	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	2.6	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	4.3	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	1.8	PID NOTCH PATHWAY	Notch signaling pathway
0.1	2.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.3	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	1.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.7	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.6	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.6	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.0	97.8	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
5.6	101.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
5.5	98.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
5.3	5.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
5.0	80.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
4.8	76.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
4.0	100.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
3.9	23.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
3.3	39.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
3.2	84.4	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
3.2	336.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
3.0	230.3	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
2.9	246.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
2.7	86.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.7	37.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
2.6	71.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
2.5	85.9	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
2.4	54.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
2.3	84.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
2.3	44.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
2.3	74.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.3	124.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
2.3	70.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
2.2	51.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
2.2	35.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
2.2	37.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
2.1	15.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
2.1	10.5	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
2.0	88.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
1.9	17.4	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
1.9	46.4	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
1.9	17.3	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
1.9	52.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
1.8	18.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
1.8	51.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
1.8	65.7	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
1.8	17.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
1.8	7.1	REACTOME ORC1 REMOVAL FROM CHROMATIN	Genes involved in Orc1 removal from chromatin
1.7	62.6	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
1.7	67.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.7	57.0	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
1.7	20.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.7	162.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
1.6	248.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
1.5	30.8	REACTOME KINESINS	Genes involved in Kinesins
1.5	58.0	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
1.4	25.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
1.4	32.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.4	26.7	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
1.4	37.7	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
1.4	27.4	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
1.4	32.4	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
1.3	38.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
1.3	6.5	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
1.3	64.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.2	12.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.2	11.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
1.2	8.6	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
1.2	42.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
1.2	14.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.2	34.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
1.1	4.6	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
1.1	18.7	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
1.1	8.8	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.1	195.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.0	10.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
1.0	17.7	REACTOME METABOLISM OF NUCLEOTIDES	Genes involved in Metabolism of nucleotides
1.0	18.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
1.0	64.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.9	60.3	REACTOME TRANSLATION	Genes involved in Translation
0.9	27.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.9	14.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.9	10.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.9	2.6	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.8	9.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.8	21.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.7	13.1	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.7	10.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.7	12.9	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.7	2.1	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.7	18.5	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.7	19.3	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.6	11.8	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.6	22.8	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.5	14.9	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.5	9.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.5	17.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.4	1.3	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.4	9.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	8.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.4	4.7	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.4	7.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.4	18.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.4	5.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.4	29.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.4	8.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4	3.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.4	2.9	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.4	11.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.4	2.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.4	10.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	3.7	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3	4.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.3	35.6	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.3	13.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.3	6.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.3	12.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.3	13.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3	8.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.3	1.8	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.2	8.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2	4.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2	2.6	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.2	4.9	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.2	3.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.2	3.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	7.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	1.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	2.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	8.9	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	10.4	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	2.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	2.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	3.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	3.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	0.7	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.1	5.2	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.1	0.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	3.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	6.5	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	1.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	1.2	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	1.9	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.5	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation