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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ELK4_ETV5_ELK1_ELK3_ELF4

Z-value: 1.69

Motif logo

Transcription factors associated with ELK4_ETV5_ELK1_ELK3_ELF4

Gene Symbol Gene ID Gene Info
ENSG00000158711.9 ETS transcription factor ELK4
ENSG00000244405.3 ETS variant transcription factor 5
ENSG00000126767.13 ETS transcription factor ELK1
ENSG00000111145.3 ETS transcription factor ELK3
ENSG00000102034.12 E74 like ETS transcription factor 4

Activity-expression correlation:

Activity profile of ELK4_ETV5_ELK1_ELK3_ELF4 motif

Sorted Z-values of ELK4_ETV5_ELK1_ELK3_ELF4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_49575058 172.85 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr1_+_32687971 161.32 ENST00000373586.1
eukaryotic translation initiation factor 3, subunit I
chr12_-_110888103 159.77 ENST00000426440.1
ENST00000228825.7
actin related protein 2/3 complex, subunit 3, 21kDa
chr2_-_73964447 155.91 ENST00000272424.5
ENST00000409716.2
ENST00000318190.7
TP53RK binding protein
chr14_-_69864993 136.26 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr5_+_110074685 133.79 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr17_+_1944790 130.73 ENST00000575162.1
diphthamide biosynthesis 1
chr5_-_140070897 129.09 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
histidyl-tRNA synthetase
chr20_-_2451395 127.40 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
small nuclear ribonucleoprotein polypeptides B and B1
chr2_+_201754050 124.90 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr1_+_203830703 124.38 ENST00000414487.2
small nuclear ribonucleoprotein polypeptide E
chr7_+_141438393 124.30 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
single-stranded DNA binding protein 1, mitochondrial
chr12_+_69080734 124.28 ENST00000378905.2
nucleoporin 107kDa
chr7_-_7680601 123.57 ENST00000396682.2
replication protein A3, 14kDa
chr2_+_201754135 117.00 ENST00000409357.1
ENST00000409129.2
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr8_-_121457332 115.39 ENST00000518918.1
mitochondrial ribosomal protein L13
chr20_-_49575081 109.65 ENST00000371588.5
ENST00000371582.4
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr3_-_186524234 109.28 ENST00000418288.1
ENST00000296273.2
replication factor C (activator 1) 4, 37kDa
chr17_-_57784755 104.44 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
peptidyl-tRNA hydrolase 2
chr21_-_33985127 104.44 ENST00000290155.3
chromosome 21 open reading frame 59
chr21_-_33984888 104.08 ENST00000382549.4
ENST00000540881.1
chromosome 21 open reading frame 59
chr5_+_892745 102.90 ENST00000166345.3
thyroid hormone receptor interactor 13
chr6_-_31926629 98.78 ENST00000375425.5
ENST00000426722.1
ENST00000441998.1
ENST00000444811.2
ENST00000375429.3
negative elongation factor complex member E
chr9_-_35103105 96.98 ENST00000452248.2
ENST00000356493.5
stomatin (EPB72)-like 2
chr11_+_118889456 96.92 ENST00000528230.1
ENST00000525303.1
ENST00000434101.2
ENST00000359005.4
ENST00000533058.1
trafficking protein particle complex 4
chr10_+_12238171 96.57 ENST00000378900.2
ENST00000442050.1
cell division cycle 123
chr21_-_33984865 95.87 ENST00000458138.1
chromosome 21 open reading frame 59
chr13_-_31191642 93.76 ENST00000405805.1
high mobility group box 1
chr7_+_141438118 93.59 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
single-stranded DNA binding protein 1, mitochondrial
chr20_+_16710606 93.39 ENST00000377943.5
ENST00000246071.6
small nuclear ribonucleoprotein polypeptide B
chr2_+_118572226 91.39 ENST00000263239.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr17_-_8113542 91.11 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr11_+_118889142 90.82 ENST00000533632.1
trafficking protein particle complex 4
chr20_+_30327063 90.20 ENST00000300403.6
ENST00000340513.4
TPX2, microtubule-associated
chr11_+_65769550 87.51 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
barrier to autointegration factor 1
chr11_+_62529008 86.70 ENST00000301788.7
ENST00000533442.1
polymerase (RNA) II (DNA directed) polypeptide G
chr1_-_169337176 86.11 ENST00000472647.1
ENST00000367811.3
NME/NM23 family member 7
chr22_-_36924944 85.95 ENST00000405442.1
ENST00000402116.1
eukaryotic translation initiation factor 3, subunit D
chr12_+_69979113 85.75 ENST00000299300.6
chaperonin containing TCP1, subunit 2 (beta)
chr10_+_12237924 85.71 ENST00000429258.2
ENST00000281141.4
cell division cycle 123
chr3_+_142720366 85.42 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2 snRNP-associated SURP domain containing
chr7_+_102988082 83.91 ENST00000292644.3
ENST00000544811.1
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr8_-_121457608 83.73 ENST00000306185.3
mitochondrial ribosomal protein L13
chr7_+_99006550 83.49 ENST00000222969.5
BUD31 homolog (S. cerevisiae)
chr7_+_5085452 82.20 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr21_-_33984456 81.53 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
Uncharacterized protein
chromosome 21 open reading frame 59
chr11_+_65769946 81.37 ENST00000533166.1
barrier to autointegration factor 1
chr2_-_55496344 81.33 ENST00000403721.1
ENST00000263629.4
mitochondrial translational initiation factor 2
chr1_-_43637915 80.48 ENST00000236051.2
EBNA1 binding protein 2
chr2_+_122494676 80.45 ENST00000455432.1
translin
chr2_+_177134134 80.22 ENST00000249442.6
ENST00000392529.2
ENST00000443241.1
metaxin 2
chr19_+_50180317 79.18 ENST00000534465.1
protein arginine methyltransferase 1
chr1_-_43855444 79.10 ENST00000372455.4
mediator complex subunit 8
chr3_-_64009102 78.65 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr12_-_112847108 78.63 ENST00000549847.1
ribosomal protein L6
chr12_+_7079944 78.01 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr4_-_120988229 77.36 ENST00000296509.6
MAD2 mitotic arrest deficient-like 1 (yeast)
chr19_+_30097181 76.97 ENST00000586420.1
ENST00000221770.3
ENST00000392279.3
ENST00000590688.1
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
chr1_+_84944926 76.73 ENST00000370656.1
ENST00000370654.5
ribosome production factor 1 homolog (S. cerevisiae)
chr5_+_33440802 76.59 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
threonyl-tRNA synthetase
chr3_-_131221790 76.57 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr12_+_69979210 76.56 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr18_+_657733 76.10 ENST00000323250.5
ENST00000323224.7
thymidylate synthetase
chr7_+_99006232 75.63 ENST00000403633.2
BUD31 homolog (S. cerevisiae)
chr22_-_36925186 75.62 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
eukaryotic translation initiation factor 3, subunit D
chr1_-_43638168 74.26 ENST00000431635.2
EBNA1 binding protein 2
chr20_-_33872548 74.03 ENST00000374443.3
eukaryotic translation initiation factor 6
chr8_-_104427313 73.93 ENST00000297578.4
solute carrier family 25 (mitochondrial folate carrier), member 32
chr1_+_93811438 72.37 ENST00000370272.4
ENST00000370267.1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr5_+_68530668 72.21 ENST00000506563.1
cyclin-dependent kinase 7
chr2_+_187350883 71.64 ENST00000337859.6
zinc finger CCCH-type containing 15
chr17_+_73008755 71.01 ENST00000584208.1
ENST00000301585.5
immature colon carcinoma transcript 1
chr12_-_112856623 71.00 ENST00000551291.2
ribosomal protein L6
chr11_-_64085533 70.73 ENST00000544844.1
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr8_-_117778494 70.71 ENST00000276682.4
eukaryotic translation initiation factor 3, subunit H
chr19_-_55791058 70.32 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr17_-_65362678 69.88 ENST00000357146.4
ENST00000356126.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr2_+_65454926 69.50 ENST00000542850.1
ENST00000377982.4
ARP2 actin-related protein 2 homolog (yeast)
chr2_-_37458749 69.39 ENST00000234170.5
CCAAT/enhancer binding protein (C/EBP), zeta
chr19_+_13261216 69.02 ENST00000587885.1
ENST00000292433.3
immediate early response 2
chr5_+_74062806 68.71 ENST00000296802.5
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr14_+_93651358 68.65 ENST00000415050.2
transmembrane protein 251
chr10_+_1034646 68.53 ENST00000360059.5
ENST00000545048.1
GTP binding protein 4
chr20_+_3190006 68.42 ENST00000380113.3
ENST00000455664.2
ENST00000399838.3
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr7_-_99698338 68.26 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr14_+_93651296 68.05 ENST00000283534.4
ENST00000557574.1
transmembrane protein 251
Uncharacterized protein
chr3_-_183602515 67.95 ENST00000449306.1
ENST00000435888.1
ENST00000311101.5
ENST00000317096.4
presenilin associated, rhomboid-like
chr6_-_31510181 67.84 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr2_-_55496174 67.38 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr5_+_140071178 67.29 ENST00000508522.1
ENST00000448069.2
histidyl-tRNA synthetase 2, mitochondrial
chr2_+_65454863 67.28 ENST00000260641.5
ARP2 actin-related protein 2 homolog (yeast)
chr7_+_30634297 67.08 ENST00000389266.3
glycyl-tRNA synthetase
chr2_+_201936707 66.16 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr14_+_35761580 65.97 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr11_+_118230287 65.93 ENST00000252108.3
ENST00000431736.2
ubiquitination factor E4A
chr12_+_6602517 65.67 ENST00000315579.5
ENST00000539714.1
non-SMC condensin I complex, subunit D2
chr5_+_167913450 65.59 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chr1_-_165738072 65.47 ENST00000481278.1
transmembrane and coiled-coil domains 1
chr15_-_34394119 65.10 ENST00000256545.4
ER membrane protein complex subunit 7
chr20_-_54967187 64.73 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
aurora kinase A
chr8_+_145133493 64.68 ENST00000316052.5
ENST00000525936.1
exosome component 4
chr2_-_99952769 64.27 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
thioredoxin domain containing 9
chr22_-_29949634 63.72 ENST00000397872.1
ENST00000397871.1
ENST00000440771.1
THO complex 5
chr2_-_70520832 63.72 ENST00000454893.1
ENST00000272348.2
small nuclear ribonucleoprotein polypeptide G
chr2_+_187350973 63.43 ENST00000544130.1
zinc finger CCCH-type containing 15
chr16_-_50402836 62.84 ENST00000394688.3
bromodomain containing 7
chr2_+_177134201 62.83 ENST00000452865.1
metaxin 2
chr2_+_198380763 62.80 ENST00000448447.2
ENST00000409360.1
MOB family member 4, phocein
chr16_-_66968265 62.69 ENST00000567511.1
ENST00000422424.2
family with sequence similarity 96, member B
chr14_+_35761540 62.67 ENST00000261479.4
proteasome (prosome, macropain) subunit, alpha type, 6
chr1_-_155990580 62.49 ENST00000531917.1
ENST00000480567.1
ENST00000526212.1
ENST00000529008.1
ENST00000496742.1
ENST00000295702.4
signal sequence receptor, beta (translocon-associated protein beta)
chr5_-_40835303 62.35 ENST00000509877.1
ENST00000508493.1
ENST00000274242.5
ribosomal protein L37
chrX_-_153775426 62.34 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr17_+_57784997 62.07 ENST00000537567.1
ENST00000539763.1
ENST00000587945.1
ENST00000536180.1
ENST00000589823.2
ENST00000592106.1
ENST00000591315.1
ENST00000545362.1
vacuole membrane protein 1
chr16_-_12009833 62.04 ENST00000420576.2
G1 to S phase transition 1
chr1_-_235324772 61.33 ENST00000408888.3
RNA binding motif protein 34
chrX_+_69509927 61.05 ENST00000374403.3
kinesin family member 4A
chr7_-_54826920 60.92 ENST00000395535.3
ENST00000352861.4
Sec61 gamma subunit
chr22_+_24951949 60.91 ENST00000402849.1
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr19_-_55791563 60.88 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr16_-_30204987 60.25 ENST00000569282.1
ENST00000567436.1
bolA family member 2B
chr1_-_236767779 59.97 ENST00000366579.1
ENST00000366582.3
ENST00000366581.2
HEAT repeat containing 1
chr16_-_50402690 59.94 ENST00000394689.2
bromodomain containing 7
chr12_+_51632638 59.74 ENST00000549732.2
DAZ associated protein 2
chr2_-_9563469 59.70 ENST00000484735.1
ENST00000456913.2
integrin beta 1 binding protein 1
chr9_+_116037922 59.70 ENST00000374198.4
pre-mRNA processing factor 4
chr11_-_60674037 59.68 ENST00000541371.1
ENST00000227524.4
pre-mRNA processing factor 19
chr5_-_140700322 59.55 ENST00000313368.5
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr1_-_1310530 59.55 ENST00000338370.3
ENST00000321751.5
ENST00000378853.3
aurora kinase A interacting protein 1
chr16_-_66968055 59.35 ENST00000568572.1
family with sequence similarity 96, member B
chr16_+_67261008 59.02 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
transmembrane protein 208
chr1_+_154947126 59.02 ENST00000368439.1
CDC28 protein kinase regulatory subunit 1B
chr17_+_57784826 58.95 ENST00000262291.4
vacuole membrane protein 1
chr1_+_231664390 58.87 ENST00000366639.4
ENST00000413309.2
translin-associated factor X
chr11_+_63754294 58.86 ENST00000543988.1
OTU domain, ubiquitin aldehyde binding 1
chr3_-_133380731 58.70 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr12_-_121019165 58.42 ENST00000341039.2
ENST00000357500.4
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr11_-_57103327 58.23 ENST00000529002.1
ENST00000278412.2
structure specific recognition protein 1
chr6_-_24666819 57.99 ENST00000341060.3
tyrosyl-DNA phosphodiesterase 2
chr14_+_77924204 57.97 ENST00000555133.1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr11_-_64084959 57.75 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr2_+_120124497 57.64 ENST00000355857.3
ENST00000535617.1
ENST00000535757.1
ENST00000409094.1
ENST00000311521.4
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr20_+_35234137 57.61 ENST00000344795.3
ENST00000373852.5
chromosome 20 open reading frame 24
chrX_+_119737806 57.58 ENST00000371317.5
malignant T cell amplified sequence 1
chr2_-_207024134 57.34 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_-_235324530 57.24 ENST00000447801.1
ENST00000366606.3
ENST00000429912.1
RNA binding motif protein 34
chr7_+_2281843 57.19 ENST00000356714.1
ENST00000397049.1
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr17_-_17184605 57.03 ENST00000268717.5
COP9 signalosome subunit 3
chr2_+_96931834 56.90 ENST00000488633.1
cytosolic iron-sulfur protein assembly 1
chr20_-_33872518 56.86 ENST00000374436.3
eukaryotic translation initiation factor 6
chr1_-_1342617 56.82 ENST00000482352.1
ENST00000344843.7
mitochondrial ribosomal protein L20
chr3_+_139062838 56.82 ENST00000310776.4
ENST00000465056.1
ENST00000465373.1
mitochondrial ribosomal protein S22
chr15_-_101835110 56.80 ENST00000560496.1
small nuclear ribonucleoprotein polypeptide A'
chr5_-_137878887 56.74 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
eukaryotic translation termination factor 1
chr2_-_230786619 56.56 ENST00000389045.3
ENST00000409677.1
thyroid hormone receptor interactor 12
chr4_+_190861941 56.27 ENST00000226798.4
FSHD region gene 1
chr9_-_127177703 55.98 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
proteasome (prosome, macropain) subunit, beta type, 7
chr1_+_110091189 55.97 ENST00000369851.4
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr5_+_10250328 55.92 ENST00000515390.1
chaperonin containing TCP1, subunit 5 (epsilon)
chr6_-_31509714 55.88 ENST00000456662.1
ENST00000431908.1
ENST00000456976.1
ENST00000428450.1
ENST00000453105.2
ENST00000418897.1
ENST00000415382.2
ENST00000449074.2
ENST00000419020.1
ENST00000428098.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr3_-_57583185 55.80 ENST00000463880.1
ADP-ribosylation factor 4
chr15_+_89787180 55.71 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
Fanconi anemia, complementation group I
chr7_+_2281882 55.69 ENST00000397046.1
ENST00000397048.1
ENST00000454650.1
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr9_+_106856831 55.61 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr5_+_68530697 55.32 ENST00000256443.3
ENST00000514676.1
cyclin-dependent kinase 7
chr17_+_49243639 55.11 ENST00000512737.1
ENST00000503064.1
NME1-NME2 readthrough
chr10_+_51371390 55.09 ENST00000478381.1
ENST00000451577.2
ENST00000374098.2
ENST00000374097.2
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr4_+_71554196 55.06 ENST00000254803.2
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr12_-_112847354 54.98 ENST00000550566.2
ENST00000553213.2
ENST00000424576.2
ENST00000202773.9
ribosomal protein L6
chr1_-_63988846 54.89 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
integrin beta 3 binding protein (beta3-endonexin)
chr17_-_8113886 54.86 ENST00000577833.1
ENST00000534871.1
ENST00000583915.1
ENST00000316199.6
ENST00000581511.1
ENST00000585124.1
aurora kinase B
chr5_+_271752 54.84 ENST00000505221.1
ENST00000509581.1
ENST00000507528.1
programmed cell death 6
chr10_-_96122682 54.82 ENST00000371361.3
nucleolar complex associated 3 homolog (S. cerevisiae)
chr12_+_69979446 54.81 ENST00000543146.2
chaperonin containing TCP1, subunit 2 (beta)
chr11_+_32605350 54.80 ENST00000531120.1
ENST00000524896.1
ENST00000323213.5
eukaryotic translation initiation factor 3, subunit M
chr15_-_55489097 54.68 ENST00000260443.4
ribosomal L24 domain containing 1
chr4_+_110736659 54.43 ENST00000394631.3
ENST00000226796.6
GAR1 ribonucleoprotein
chr2_+_201676256 54.18 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
basic leucine zipper and W2 domains 1
chr14_+_75348592 54.00 ENST00000334220.4
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr2_-_70520539 53.95 ENST00000482975.2
ENST00000438261.1
small nuclear ribonucleoprotein polypeptide G
chr1_+_40723779 53.83 ENST00000372759.3
zinc metallopeptidase STE24
chr1_+_45205498 53.76 ENST00000372218.4
kinesin family member 2C
chr15_+_69706585 53.74 ENST00000559279.1
ENST00000395392.2
kinesin family member 23
chr11_-_9336234 53.67 ENST00000528080.1
transmembrane protein 41B
chrX_+_21958814 53.61 ENST00000379404.1
ENST00000415881.2
spermine synthase
chr4_+_190861993 53.55 ENST00000524583.1
ENST00000531991.2
FSHD region gene 1
chr5_+_134094461 53.08 ENST00000452510.2
ENST00000354283.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr7_-_2281802 53.08 ENST00000242257.8
ENST00000440306.2
FtsJ RNA methyltransferase homolog 2 (E. coli)
chr11_-_77348796 53.07 ENST00000263309.3
ENST00000525064.1
chloride channel, nucleotide-sensitive, 1A
chr10_-_58120996 52.91 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZW10 interacting kinetochore protein
chr20_+_35234223 52.87 ENST00000342422.3
chromosome 20 open reading frame 24
chr17_-_47022140 52.80 ENST00000290330.3
SNF8, ESCRT-II complex subunit
chr19_-_55791540 52.68 ENST00000433386.2
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr11_+_10772534 52.44 ENST00000361367.2
CTR9, Paf1/RNA polymerase II complex component
chr2_+_99225018 52.40 ENST00000357765.2
ENST00000409975.1
unc-50 homolog (C. elegans)
chr8_-_67974552 52.24 ENST00000357849.4
COP9 signalosome subunit 5
chr19_+_9938562 52.16 ENST00000586895.1
ENST00000358666.3
ENST00000590068.1
ENST00000593087.1
ubiquitin-like 5
chr14_+_57735614 52.08 ENST00000261558.3
adaptor-related protein complex 5, mu 1 subunit
chr20_+_388935 52.06 ENST00000382181.2
ENST00000400247.3
RanBP-type and C3HC4-type zinc finger containing 1
chr3_-_10362725 52.01 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13 homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of ELK4_ETV5_ELK1_ELK3_ELF4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
73.1 219.4 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
72.4 217.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
58.8 294.2 GO:0019348 dolichol metabolic process(GO:0019348)
55.7 167.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
50.0 150.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
48.7 146.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
48.4 145.3 GO:0090149 mitochondrial membrane fission(GO:0090149)
47.9 191.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
41.8 167.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
40.1 120.2 GO:0046680 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
40.0 120.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
39.5 157.8 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
36.8 73.5 GO:0002188 translation reinitiation(GO:0002188)
35.9 143.5 GO:0010796 regulation of multivesicular body size(GO:0010796)
35.4 106.2 GO:0006597 spermine biosynthetic process(GO:0006597)
34.6 138.4 GO:0032218 riboflavin transport(GO:0032218)
34.3 103.0 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
33.9 169.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
33.8 168.8 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
33.3 33.3 GO:0007224 smoothened signaling pathway(GO:0007224)
32.3 129.0 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
32.2 96.7 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
32.0 96.0 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
31.1 124.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
29.7 148.7 GO:0032790 ribosome disassembly(GO:0032790)
29.7 119.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
29.7 29.7 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
29.5 29.5 GO:0007096 regulation of exit from mitosis(GO:0007096)
29.2 87.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
29.1 87.3 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
28.8 86.3 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
28.7 229.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
28.5 85.4 GO:0033341 regulation of collagen binding(GO:0033341)
28.2 84.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
28.1 84.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
28.1 112.3 GO:0006203 dGTP catabolic process(GO:0006203)
27.5 137.6 GO:0075525 viral translational termination-reinitiation(GO:0075525)
27.0 108.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
26.6 106.5 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
26.1 78.3 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
26.0 52.1 GO:0046070 dGTP metabolic process(GO:0046070)
25.9 77.7 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
25.7 102.9 GO:0007144 female meiosis I(GO:0007144)
25.7 77.0 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
25.6 102.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
25.0 100.0 GO:0016074 snoRNA metabolic process(GO:0016074)
24.5 244.6 GO:0051096 positive regulation of helicase activity(GO:0051096)
24.3 97.3 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296)
24.2 48.4 GO:0043096 purine nucleobase salvage(GO:0043096)
23.6 164.9 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
23.1 115.5 GO:0002084 protein depalmitoylation(GO:0002084)
22.8 137.0 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
22.8 68.4 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
22.7 227.3 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
21.9 65.8 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
21.8 87.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
21.7 21.7 GO:0015698 inorganic anion transport(GO:0015698)
20.9 188.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
20.5 328.4 GO:0043248 proteasome assembly(GO:0043248)
20.0 60.0 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
19.9 79.7 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
19.8 59.4 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
19.8 19.8 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
19.5 58.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
19.3 135.2 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
18.3 109.9 GO:0070475 rRNA base methylation(GO:0070475)
18.3 36.6 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
18.3 54.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
18.0 54.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
18.0 54.0 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
18.0 108.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
17.9 53.6 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
17.8 17.8 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
17.8 53.4 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
17.6 17.6 GO:2000644 regulation of receptor catabolic process(GO:2000644) negative regulation of receptor catabolic process(GO:2000645)
17.5 855.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
17.4 69.5 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
17.4 52.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
17.1 154.0 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
17.0 204.4 GO:0015074 DNA integration(GO:0015074)
16.6 66.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
16.6 49.7 GO:0035927 RNA import into mitochondrion(GO:0035927)
15.9 47.7 GO:0006624 vacuolar protein processing(GO:0006624)
15.9 47.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
15.3 1679.6 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
15.2 60.9 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
15.2 685.3 GO:0036260 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
15.2 45.6 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
15.2 45.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
15.1 60.3 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
15.0 45.0 GO:1903722 regulation of centriole elongation(GO:1903722)
14.7 58.8 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
14.6 161.1 GO:0090151 protein import into mitochondrial outer membrane(GO:0045040) establishment of protein localization to mitochondrial membrane(GO:0090151)
14.6 131.7 GO:1904872 regulation of telomerase RNA localization to Cajal body(GO:1904872)
14.6 43.7 GO:0042256 mature ribosome assembly(GO:0042256)
14.5 58.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
14.2 42.7 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
14.2 14.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
13.9 222.1 GO:0000338 protein deneddylation(GO:0000338)
13.9 110.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
13.8 83.0 GO:1904431 positive regulation of t-circle formation(GO:1904431)
13.8 41.4 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
13.8 428.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
13.8 137.5 GO:0018202 peptidyl-histidine modification(GO:0018202)
13.7 631.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
13.6 108.8 GO:2000210 positive regulation of anoikis(GO:2000210)
13.5 67.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
13.5 26.9 GO:0036493 positive regulation of translation in response to stress(GO:0032056) positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
13.3 93.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
13.3 26.6 GO:0033182 regulation of histone ubiquitination(GO:0033182)
13.3 13.3 GO:0006404 RNA import into nucleus(GO:0006404)
13.1 65.7 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
13.1 26.1 GO:1901656 glycoside transport(GO:1901656)
12.8 77.1 GO:1902661 positive regulation of glucose mediated signaling pathway(GO:1902661)
12.7 38.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
12.6 25.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
12.6 50.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
12.6 75.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
12.3 61.6 GO:1905216 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
12.3 49.3 GO:0071492 cellular response to UV-A(GO:0071492)
12.3 61.6 GO:0098502 DNA dephosphorylation(GO:0098502)
12.3 196.2 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
12.2 24.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
12.1 72.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
12.1 36.3 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
12.0 120.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
12.0 204.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
12.0 852.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
11.7 152.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
11.7 163.4 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
11.6 128.0 GO:0031584 activation of phospholipase D activity(GO:0031584)
11.5 23.1 GO:0097327 response to antineoplastic agent(GO:0097327)
11.5 23.0 GO:0019322 pentose biosynthetic process(GO:0019322)
11.5 80.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
11.4 68.2 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
11.3 79.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
11.3 203.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
11.3 22.5 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
11.2 33.6 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
11.1 122.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
11.0 33.0 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
11.0 32.9 GO:0097212 lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
10.9 32.8 GO:0051685 maintenance of ER location(GO:0051685)
10.9 43.7 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
10.8 65.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
10.5 52.7 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
10.5 284.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
10.5 21.0 GO:0006172 ADP biosynthetic process(GO:0006172)
10.4 239.5 GO:0042255 ribosome assembly(GO:0042255)
10.4 52.0 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
10.4 52.0 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosomal large subunit export from nucleus(GO:0000055) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
10.2 92.2 GO:0006983 ER overload response(GO:0006983)
10.0 220.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
10.0 19.9 GO:2000653 regulation of genetic imprinting(GO:2000653)
10.0 49.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
9.9 79.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
9.8 39.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
9.8 59.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
9.8 39.1 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
9.8 9.8 GO:1904868 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
9.7 97.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
9.6 192.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
9.6 623.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
9.6 9.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
9.6 47.8 GO:0046203 spermidine catabolic process(GO:0046203)
9.6 28.7 GO:0000076 DNA replication checkpoint(GO:0000076)
9.6 28.7 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
9.5 38.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
9.4 47.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
9.4 75.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
9.2 27.5 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
9.2 18.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
9.1 45.7 GO:0031125 rRNA 3'-end processing(GO:0031125)
9.1 45.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
8.9 26.8 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
8.8 123.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
8.8 26.5 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
8.8 44.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
8.8 44.0 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
8.8 8.8 GO:0048254 snoRNA localization(GO:0048254)
8.7 313.5 GO:0042407 cristae formation(GO:0042407)
8.7 52.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
8.7 26.0 GO:1901873 regulation of post-translational protein modification(GO:1901873)
8.6 51.6 GO:0015866 ADP transport(GO:0015866)
8.6 25.8 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
8.6 25.7 GO:0070632 spindle pole body duplication(GO:0030474) nuclear pore distribution(GO:0031081) spindle pole body organization(GO:0051300) nuclear pore localization(GO:0051664) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
8.5 25.6 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
8.4 50.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
8.4 92.9 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
8.4 50.3 GO:0051013 microtubule severing(GO:0051013)
8.4 25.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
8.3 8.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
8.3 24.8 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
8.2 24.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
8.2 181.2 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
8.1 80.9 GO:0045116 protein neddylation(GO:0045116)
8.1 129.3 GO:0018345 protein palmitoylation(GO:0018345)
8.0 8.0 GO:0061511 centriole elongation(GO:0061511)
8.0 32.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
8.0 32.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
8.0 8.0 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
7.8 23.4 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
7.8 7.8 GO:0006167 AMP biosynthetic process(GO:0006167)
7.7 123.2 GO:0060546 negative regulation of necroptotic process(GO:0060546)
7.6 15.2 GO:1901355 response to rapamycin(GO:1901355)
7.6 83.3 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
7.5 60.1 GO:0015846 polyamine transport(GO:0015846)
7.5 44.9 GO:0007386 compartment pattern specification(GO:0007386)
7.5 7.5 GO:0050773 regulation of dendrite development(GO:0050773) positive regulation of dendrite development(GO:1900006)
7.4 14.9 GO:0009303 rRNA transcription(GO:0009303)
7.4 22.2 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
7.3 7.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
7.3 36.7 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
7.3 44.0 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
7.3 803.2 GO:0045047 protein targeting to ER(GO:0045047)
7.3 43.8 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
7.3 21.9 GO:0015680 intracellular copper ion transport(GO:0015680)
7.2 14.5 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
7.2 28.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
7.2 7.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
7.1 7.1 GO:0001302 replicative cell aging(GO:0001302)
7.1 35.3 GO:0001887 selenium compound metabolic process(GO:0001887)
7.0 14.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
7.0 28.1 GO:0016240 autophagosome docking(GO:0016240)
7.0 21.0 GO:0046294 formaldehyde catabolic process(GO:0046294)
7.0 7.0 GO:0046102 inosine metabolic process(GO:0046102)
7.0 13.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
6.9 6.9 GO:0043335 protein unfolding(GO:0043335)
6.9 6.9 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
6.9 6.9 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
6.8 218.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
6.7 20.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
6.6 39.7 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
6.6 6.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
6.5 19.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
6.5 32.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
6.4 122.0 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
6.4 38.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
6.4 25.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
6.4 19.1 GO:1902570 protein localization to nucleolus(GO:1902570)
6.3 25.4 GO:0072719 cellular response to cisplatin(GO:0072719)
6.3 31.7 GO:0030047 actin modification(GO:0030047)
6.3 19.0 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
6.3 31.5 GO:0034720 histone H3-K4 demethylation(GO:0034720)
6.3 37.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
6.2 6.2 GO:0003162 atrioventricular node development(GO:0003162)
6.2 49.7 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
6.2 105.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
6.2 31.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
6.2 55.6 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
6.2 37.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
6.2 67.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
6.2 6.2 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
6.1 73.8 GO:0000920 cell separation after cytokinesis(GO:0000920)
6.0 24.0 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
6.0 59.9 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
6.0 17.9 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
5.9 5.9 GO:0019087 transformation of host cell by virus(GO:0019087)
5.9 29.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
5.9 117.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
5.9 17.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
5.9 193.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
5.7 17.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
5.7 28.7 GO:0033523 histone H2B ubiquitination(GO:0033523)
5.7 11.5 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
5.7 17.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
5.7 11.3 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
5.6 16.9 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
5.6 22.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
5.6 56.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
5.6 16.8 GO:0015920 lipopolysaccharide transport(GO:0015920)
5.6 536.2 GO:0006413 translational initiation(GO:0006413)
5.6 61.4 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
5.6 44.4 GO:0022417 protein maturation by protein folding(GO:0022417)
5.5 22.1 GO:0030242 pexophagy(GO:0030242)
5.5 16.5 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
5.5 33.0 GO:0070200 establishment of protein localization to telomere(GO:0070200)
5.5 27.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
5.4 216.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
5.4 37.6 GO:2000773 negative regulation of cellular senescence(GO:2000773)
5.4 21.5 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
5.3 101.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
5.3 31.9 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
5.3 42.5 GO:1902969 mitotic DNA replication(GO:1902969)
5.3 58.4 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
5.3 26.4 GO:0007619 courtship behavior(GO:0007619)
5.2 5.2 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
5.2 41.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
5.2 51.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
5.2 25.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
5.1 51.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
5.1 35.9 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
5.1 10.1 GO:1904796 regulation of core promoter binding(GO:1904796)
5.0 40.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
5.0 10.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
5.0 30.0 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
5.0 15.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
5.0 19.9 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
5.0 5.0 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
4.9 49.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
4.9 14.8 GO:0071314 cellular response to cocaine(GO:0071314)
4.9 29.5 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
4.8 14.5 GO:0072321 chaperone-mediated protein transport(GO:0072321)
4.8 19.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
4.8 23.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
4.7 56.9 GO:0051307 meiotic chromosome separation(GO:0051307)
4.7 28.3 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
4.7 37.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
4.7 46.9 GO:0015939 pantothenate metabolic process(GO:0015939)
4.7 84.4 GO:0035641 locomotory exploration behavior(GO:0035641)
4.7 420.6 GO:0048208 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
4.7 37.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
4.7 51.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
4.6 13.9 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
4.6 59.9 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
4.6 303.7 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
4.6 27.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
4.6 18.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
4.5 4.5 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
4.5 9.0 GO:0009147 pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
4.5 4.5 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
4.5 156.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
4.4 22.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
4.3 73.9 GO:0006465 signal peptide processing(GO:0006465)
4.3 17.4 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
4.3 13.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
4.3 17.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
4.3 17.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
4.3 8.5 GO:1902410 mitotic cytokinetic process(GO:1902410)
4.3 47.0 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
4.2 16.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
4.2 8.4 GO:1900063 regulation of peroxisome organization(GO:1900063)
4.2 79.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
4.2 79.7 GO:0006337 nucleosome disassembly(GO:0006337)
4.2 8.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
4.2 12.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
4.2 4.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
4.2 45.7 GO:0090168 Golgi reassembly(GO:0090168)
4.1 107.6 GO:0006270 DNA replication initiation(GO:0006270)
4.1 24.8 GO:0008053 mitochondrial fusion(GO:0008053)
4.1 16.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
4.1 237.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
4.1 12.3 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
4.1 36.7 GO:0051383 kinetochore organization(GO:0051383)
4.0 24.2 GO:0000212 meiotic spindle organization(GO:0000212)
4.0 4.0 GO:0071223 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
4.0 8.0 GO:0043400 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
4.0 32.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
4.0 24.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
4.0 44.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
4.0 68.0 GO:0006415 translational termination(GO:0006415)
3.9 86.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
3.9 7.9 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
3.9 35.3 GO:0018344 protein geranylgeranylation(GO:0018344)
3.9 11.7 GO:0071421 manganese ion transmembrane transport(GO:0071421)
3.9 23.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
3.9 57.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
3.8 3.8 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
3.8 7.6 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
3.8 53.5 GO:0051290 protein heterotetramerization(GO:0051290)
3.8 7.6 GO:0034214 protein hexamerization(GO:0034214)
3.8 15.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
3.8 11.4 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
3.8 19.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
3.8 15.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
3.8 83.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
3.8 22.7 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
3.8 11.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
3.8 18.8 GO:1902739 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
3.7 3.7 GO:0006097 glyoxylate cycle(GO:0006097)
3.7 55.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
3.7 11.0 GO:0006089 lactate metabolic process(GO:0006089)
3.7 22.0 GO:0007296 vitellogenesis(GO:0007296)
3.6 7.3 GO:0035435 phosphate ion transport(GO:0006817) phosphate ion transmembrane transport(GO:0035435)
3.6 18.2 GO:0042262 DNA protection(GO:0042262)
3.6 10.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
3.5 35.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
3.5 49.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
3.5 7.0 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
3.5 7.0 GO:0052042 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
3.5 6.9 GO:1903978 regulation of microglial cell activation(GO:1903978)
3.4 6.9 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
3.4 3.4 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
3.4 41.3 GO:0044818 mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818)
3.4 47.6 GO:0000002 mitochondrial genome maintenance(GO:0000002)
3.4 71.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
3.4 3.4 GO:0034398 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
3.4 3.4 GO:0051684 maintenance of Golgi location(GO:0051684)
3.4 30.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
3.3 6.7 GO:0007369 gastrulation(GO:0007369)
3.3 23.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
3.3 10.0 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
3.3 16.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
3.3 66.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
3.3 215.3 GO:0045454 cell redox homeostasis(GO:0045454)
3.3 13.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
3.3 33.1 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
3.3 16.4 GO:0009838 abscission(GO:0009838)
3.3 19.6 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
3.3 9.8 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
3.2 6.5 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
3.2 3.2 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
3.2 57.5 GO:0006825 copper ion transport(GO:0006825)
3.2 16.0 GO:0039530 MDA-5 signaling pathway(GO:0039530)
3.2 25.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
3.1 3.1 GO:0051030 snRNA transport(GO:0051030)
3.1 6.3 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
3.1 34.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
3.1 9.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
3.1 34.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
3.1 9.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
3.1 27.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
3.1 6.2 GO:1903333 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
3.1 37.1 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
3.1 24.5 GO:0010265 SCF complex assembly(GO:0010265)
3.1 143.9 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
3.0 39.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
3.0 3.0 GO:0070341 fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344) negative regulation of fat cell proliferation(GO:0070345)
3.0 3.0 GO:0060296 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
3.0 6.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
3.0 41.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
2.9 8.8 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
2.9 11.6 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
2.9 8.7 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
2.9 31.8 GO:0006105 succinate metabolic process(GO:0006105)
2.9 2.9 GO:0045210 FasL biosynthetic process(GO:0045210)
2.9 8.6 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
2.9 8.6 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
2.9 8.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
2.8 8.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
2.8 143.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
2.8 2.8 GO:0048372 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
2.8 2.8 GO:0034508 centromere complex assembly(GO:0034508)
2.8 25.0 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
2.8 16.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
2.7 736.0 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
2.7 8.2 GO:0034982 mitochondrial protein processing(GO:0034982)
2.7 32.5 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
2.7 16.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
2.7 29.7 GO:0051601 exocyst localization(GO:0051601)
2.7 5.4 GO:1904044 response to aldosterone(GO:1904044)
2.7 10.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
2.7 10.7 GO:0043555 regulation of translation in response to stress(GO:0043555)
2.7 77.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
2.7 8.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
2.6 2.6 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
2.6 10.6 GO:0071044 histone mRNA catabolic process(GO:0071044)
2.6 73.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
2.6 26.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
2.6 5.2 GO:0090114 COPII-coated vesicle budding(GO:0090114)
2.6 26.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
2.6 2.6 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
2.6 7.8 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
2.6 18.1 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
2.6 15.5 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
2.6 7.7 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
2.6 15.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.6 66.8 GO:0009235 cobalamin metabolic process(GO:0009235)
2.6 12.8 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
2.6 17.9 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
2.6 10.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
2.5 50.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
2.5 10.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
2.5 2.5 GO:0070671 response to interleukin-12(GO:0070671)
2.5 97.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
2.5 14.9 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
2.5 12.4 GO:0051026 chiasma assembly(GO:0051026)
2.5 32.0 GO:0006119 oxidative phosphorylation(GO:0006119)
2.5 7.4 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
2.5 12.3 GO:2000035 regulation of stem cell division(GO:2000035)
2.4 7.3 GO:0071500 cellular response to nitrosative stress(GO:0071500)
2.4 7.3 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
2.4 22.0 GO:1902591 single-organism membrane budding(GO:1902591)
2.4 9.7 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
2.4 165.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
2.4 4.9 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
2.4 4.8 GO:0001923 B-1 B cell differentiation(GO:0001923)
2.4 7.2 GO:1902896 terminal web assembly(GO:1902896)
2.4 40.9 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
2.4 7.2 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
2.4 23.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
2.4 57.1 GO:0006903 vesicle targeting(GO:0006903)
2.4 4.8 GO:0051014 actin filament severing(GO:0051014)
2.4 2.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
2.4 25.9 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
2.3 11.7 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
2.3 118.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
2.3 9.2 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
2.3 43.6 GO:0035855 megakaryocyte development(GO:0035855)
2.3 2.3 GO:0070384 Harderian gland development(GO:0070384)
2.3 11.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
2.3 11.4 GO:0015862 uridine transport(GO:0015862)
2.3 2.3 GO:0050919 negative chemotaxis(GO:0050919)
2.3 40.6 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
2.2 6.7 GO:0032497 detection of lipopolysaccharide(GO:0032497)
2.2 13.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
2.2 6.6 GO:0070933 histone H4 deacetylation(GO:0070933)
2.2 15.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
2.2 2.2 GO:0031291 Ran protein signal transduction(GO:0031291)
2.1 8.6 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
2.1 6.4 GO:0051661 maintenance of centrosome location(GO:0051661)
2.1 2.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
2.1 6.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
2.1 2.1 GO:0040031 snRNA modification(GO:0040031)
2.1 25.5 GO:0021670 lateral ventricle development(GO:0021670)
2.1 27.6 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
2.1 12.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
2.1 88.2 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
2.1 4.2 GO:0044827 modulation by host of viral genome replication(GO:0044827)
2.1 4.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
2.1 10.4 GO:0045963 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
2.1 12.5 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
2.1 14.5 GO:0035268 protein mannosylation(GO:0035268)
2.1 16.5 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
2.1 57.6 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
2.0 57.2 GO:0000281 mitotic cytokinesis(GO:0000281)
2.0 12.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
2.0 4.1 GO:0046292 spermatid nucleus elongation(GO:0007290) formaldehyde metabolic process(GO:0046292)
2.0 4.0 GO:0003415 chondrocyte hypertrophy(GO:0003415)
2.0 4.0 GO:0044351 macropinocytosis(GO:0044351)
2.0 4.0 GO:0030043 actin filament fragmentation(GO:0030043)
2.0 8.0 GO:0090170 regulation of Golgi inheritance(GO:0090170)
2.0 18.0 GO:0002934 desmosome organization(GO:0002934)
2.0 5.9 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
2.0 7.9 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
1.9 25.0 GO:0016578 histone deubiquitination(GO:0016578)
1.9 1.9 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
1.9 23.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.9 7.6 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
1.9 11.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
1.9 22.7 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
1.9 5.7 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
1.9 3.7 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
1.9 5.6 GO:0044068 modulation by symbiont of host cellular process(GO:0044068)
1.9 5.6 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
1.9 7.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
1.9 20.5 GO:0010815 bradykinin catabolic process(GO:0010815)
1.9 52.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
1.9 3.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.8 9.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
1.8 7.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
1.8 14.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.8 17.8 GO:0045793 positive regulation of cell size(GO:0045793)
1.8 5.3 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
1.8 7.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.8 10.6 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.8 14.1 GO:0018065 protein-cofactor linkage(GO:0018065)
1.7 22.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.7 13.9 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.7 69.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
1.7 1.7 GO:0010039 response to iron ion(GO:0010039)
1.7 6.7 GO:0030259 lipid glycosylation(GO:0030259)
1.7 6.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
1.6 39.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
1.6 1.6 GO:0033591 response to L-ascorbic acid(GO:0033591)
1.6 1.6 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
1.6 3.3 GO:0042572 retinol metabolic process(GO:0042572)
1.6 14.6 GO:0042074 cell migration involved in gastrulation(GO:0042074)
1.6 6.5 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
1.6 6.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.6 32.2 GO:0031639 plasminogen activation(GO:0031639)
1.6 22.5 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
1.6 8.0 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.6 6.4 GO:1905031 regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
1.6 9.5 GO:0000012 single strand break repair(GO:0000012)
1.6 7.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.5 7.7 GO:1904355 positive regulation of telomere capping(GO:1904355)
1.5 13.8 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.5 6.1 GO:0006183 GMP biosynthetic process(GO:0006177) GTP biosynthetic process(GO:0006183)
1.5 4.5 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
1.5 22.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
1.5 13.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.5 4.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
1.5 5.9 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.5 1.5 GO:0032928 regulation of superoxide anion generation(GO:0032928) positive regulation of superoxide anion generation(GO:0032930)
1.5 2.9 GO:0002643 tolerance induction(GO:0002507) regulation of tolerance induction(GO:0002643)
1.4 39.0 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
1.4 44.8 GO:0090383 phagosome acidification(GO:0090383)
1.4 18.7 GO:0019388 galactose catabolic process(GO:0019388)
1.4 5.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
1.4 12.9 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
1.4 12.9 GO:0018916 nitrobenzene metabolic process(GO:0018916)
1.4 11.4 GO:0016925 protein sumoylation(GO:0016925)
1.4 19.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
1.4 5.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
1.4 6.9 GO:0035897 proteolysis in other organism(GO:0035897)
1.4 1.4 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
1.4 5.4 GO:0006740 NADPH regeneration(GO:0006740)
1.4 6.8 GO:0070980 biphenyl catabolic process(GO:0070980)
1.4 5.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
1.3 5.4 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
1.3 99.0 GO:0070527 platelet aggregation(GO:0070527)
1.3 1.3 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
1.3 7.9 GO:0070266 necroptotic process(GO:0070266)
1.3 3.9 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
1.3 3.9 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
1.3 2.6 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
1.3 5.2 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
1.3 7.8 GO:0070672 response to interleukin-15(GO:0070672)
1.3 19.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
1.3 5.2 GO:0006543 glutamine catabolic process(GO:0006543)
1.3 65.9 GO:0007062 sister chromatid cohesion(GO:0007062)
1.3 11.5 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
1.3 74.2 GO:0043488 regulation of mRNA stability(GO:0043488)
1.3 27.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
1.3 8.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.2 10.0 GO:0014870 response to muscle inactivity(GO:0014870)
1.2 6.2 GO:0006379 mRNA cleavage(GO:0006379)
1.2 22.2 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
1.2 16.0 GO:0007018 microtubule-based movement(GO:0007018)
1.2 17.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
1.2 1.2 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
1.2 4.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.2 3.6 GO:0042369 vitamin D catabolic process(GO:0042369)
1.2 9.7 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.2 7.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
1.2 1.2 GO:0051182 coenzyme transport(GO:0051182)
1.2 8.4 GO:0001503 ossification(GO:0001503)
1.2 2.4 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
1.2 7.2 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
1.2 7.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
1.2 1.2 GO:0060406 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
1.2 9.5 GO:0048311 mitochondrion distribution(GO:0048311)
1.2 13.0 GO:0060576 intestinal epithelial cell development(GO:0060576)
1.2 2.4 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
1.2 4.7 GO:1903224 regulation of endodermal cell differentiation(GO:1903224) negative regulation of gastrulation(GO:2000542)
1.2 7.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.2 34.1 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
1.2 8.2 GO:0030091 protein repair(GO:0030091)
1.2 4.7 GO:0035879 plasma membrane lactate transport(GO:0035879)
1.2 3.5 GO:0006591 ornithine metabolic process(GO:0006591)
1.2 2.3 GO:0019401 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
1.1 3.4 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
1.1 4.6 GO:0035067 negative regulation of histone acetylation(GO:0035067)
1.1 8.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.1 2.3 GO:2000347 positive regulation of hepatocyte proliferation(GO:2000347)
1.1 33.0 GO:0014904 myotube cell development(GO:0014904)
1.1 45.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
1.1 10.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
1.1 4.5 GO:0031269 pseudopodium assembly(GO:0031269)
1.1 41.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
1.1 19.0 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
1.1 8.9 GO:0002051 osteoblast fate commitment(GO:0002051)
1.1 14.5 GO:0060712 spongiotrophoblast layer development(GO:0060712)
1.1 4.5 GO:1990834 response to odorant(GO:1990834)
1.1 2.2 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.1 13.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.1 6.6 GO:0060235 lens induction in camera-type eye(GO:0060235)
1.1 16.5 GO:0043388 positive regulation of DNA binding(GO:0043388)
1.1 4.4 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086)
1.1 2.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.1 2.2 GO:0006788 heme oxidation(GO:0006788)
1.1 2.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
1.1 7.5 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
1.1 8.6 GO:0071402 cellular response to lipoprotein particle stimulus(GO:0071402)
1.1 25.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
1.1 22.5 GO:0007019 microtubule depolymerization(GO:0007019)
1.1 7.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
1.1 2.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
1.1 3.2 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.1 3.2 GO:0061724 lipophagy(GO:0061724)
1.1 1.1 GO:1904181 positive regulation of membrane depolarization(GO:1904181)
1.0 14.4 GO:0035455 response to interferon-alpha(GO:0035455)
1.0 7.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
1.0 3.0 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
1.0 24.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
1.0 3.0 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
1.0 6.0 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.0 33.5 GO:0035987 endodermal cell differentiation(GO:0035987)
1.0 6.9 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
1.0 5.9 GO:1990182 exosomal secretion(GO:1990182)
1.0 2.9 GO:0006550 isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550)
1.0 2.9 GO:0006642 triglyceride mobilization(GO:0006642)
1.0 17.5 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
1.0 1.9 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
1.0 15.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
1.0 3.8 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
1.0 4.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
1.0 9.5 GO:0051764 actin crosslink formation(GO:0051764)
1.0 51.3 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.9 17.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.9 35.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.9 1.9 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.9 3.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.9 1.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.9 1.9 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.9 3.7 GO:0021553 olfactory nerve development(GO:0021553)
0.9 3.6 GO:0000103 sulfate assimilation(GO:0000103)
0.9 5.4 GO:0035065 regulation of histone acetylation(GO:0035065)
0.9 3.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.9 0.9 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.9 6.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.9 4.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.9 2.6 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.9 7.7 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.8 7.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.8 3.4 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.8 0.8 GO:0032808 lacrimal gland development(GO:0032808)
0.8 5.9 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.8 0.8 GO:0035483 gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.8 1.6 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.8 2.4 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.8 0.8 GO:0061684 chaperone-mediated autophagy(GO:0061684)
0.8 13.0 GO:0048278 vesicle docking(GO:0048278)
0.8 3.2 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.8 4.0 GO:0015914 phospholipid transport(GO:0015914)
0.8 2.4 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.8 0.8 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.8 2.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.8 6.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.8 2.4 GO:1902498 regulation of protein autoubiquitination(GO:1902498) positive regulation of protein autoubiquitination(GO:1902499)
0.8 6.3 GO:0015816 glycine transport(GO:0015816)
0.8 5.5 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.8 7.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.8 3.9 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.8 7.0 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.8 3.9 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.8 24.7 GO:0006611 protein export from nucleus(GO:0006611)
0.8 21.6 GO:0015893 drug transport(GO:0015893)
0.8 2.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.8 10.6 GO:0006623 protein targeting to vacuole(GO:0006623)
0.8 10.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.8 7.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.8 13.5 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.7 8.9 GO:0016180 snRNA processing(GO:0016180)
0.7 2.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.7 9.4 GO:0032801 receptor catabolic process(GO:0032801)
0.7 5.1 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.7 7.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.7 35.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.7 3.5 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.7 2.8 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.7 4.9 GO:0046836 glycolipid transport(GO:0046836)
0.7 3.5 GO:0031648 protein destabilization(GO:0031648)
0.7 22.3 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.7 5.6 GO:0005984 disaccharide metabolic process(GO:0005984)
0.7 0.7 GO:0043366 beta selection(GO:0043366)
0.7 12.5 GO:0034205 beta-amyloid formation(GO:0034205)
0.7 5.5 GO:0015886 heme transport(GO:0015886)
0.7 23.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.7 2.7 GO:0061146 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.7 0.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.7 0.7 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.7 10.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.7 3.9 GO:0051012 microtubule sliding(GO:0051012)
0.6 0.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.6 11.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.6 3.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.6 1.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.6 3.7 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.6 0.6 GO:0071888 macrophage apoptotic process(GO:0071888)
0.6 1.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.6 0.6 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.6 4.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.6 2.4 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.6 11.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.6 4.8 GO:0007160 cell-matrix adhesion(GO:0007160)
0.6 6.0 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.6 1.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.6 1.8 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.6 2.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.6 2.9 GO:0032328 alanine transport(GO:0032328)
0.5 9.3 GO:0016540 protein autoprocessing(GO:0016540)
0.5 4.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.5 1.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.5 9.2 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.5 3.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.5 2.7 GO:0060430 lung saccule development(GO:0060430) alveolar primary septum development(GO:0061143)
0.5 3.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.5 1.1 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.5 2.6 GO:1902946 protein localization to early endosome(GO:1902946)
0.5 12.6 GO:0008210 estrogen metabolic process(GO:0008210)
0.5 1.6 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.5 21.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.5 2.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.5 13.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.5 1.5 GO:0007097 nuclear migration(GO:0007097)
0.5 1.5 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.5 5.5 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.5 4.5 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.5 1.5 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.5 6.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.5 2.9 GO:0008356 asymmetric cell division(GO:0008356)
0.5 0.5 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.5 2.4 GO:0033500 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.5 1.9 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.5 9.6 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.5 4.3 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.5 26.4 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.5 3.8 GO:0032610 interleukin-1 alpha production(GO:0032610)
0.5 2.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.5 1.9 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.5 2.4 GO:0060356 leucine import(GO:0060356)
0.5 5.7 GO:0006378 mRNA polyadenylation(GO:0006378)
0.5 4.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.5 3.7 GO:0017085 response to insecticide(GO:0017085)
0.5 2.3 GO:1903416 response to glycoside(GO:1903416)
0.5 13.4 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.5 2.3 GO:0050711 negative regulation of interleukin-1 secretion(GO:0050711)
0.5 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.5 6.0 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.5 4.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.5 2.7 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.5 1.4 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.5 0.5 GO:0009218 pyrimidine ribonucleotide metabolic process(GO:0009218)
0.4 2.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.4 0.9 GO:0071320 cellular response to cAMP(GO:0071320)
0.4 2.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.4 1.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.4 0.4 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.4 0.4 GO:0010269 response to selenium ion(GO:0010269)
0.4 1.3 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.4 8.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.4 1.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.4 4.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.4 9.5 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.4 0.8 GO:0061355 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.4 1.6 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.4 2.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.4 2.0 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.4 0.8 GO:0051262 protein tetramerization(GO:0051262)
0.4 8.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.4 5.0 GO:0002021 response to dietary excess(GO:0002021)
0.4 1.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.4 3.0 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.4 1.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.4 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.4 4.6 GO:0048569 post-embryonic organ development(GO:0048569)
0.4 2.5 GO:0033260 nuclear DNA replication(GO:0033260)
0.3 1.4 GO:0048286 lung alveolus development(GO:0048286)
0.3 0.7 GO:0030307 positive regulation of cell growth(GO:0030307)
0.3 2.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.3 0.7 GO:0046185 aldehyde catabolic process(GO:0046185)
0.3 2.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.3 2.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 19.1 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3 2.9 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.3 2.5 GO:0070995 NADPH oxidation(GO:0070995)
0.3 11.5 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.3 0.9 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.3 0.3 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.3 2.4 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.3 15.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.3 6.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.3 0.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.3 7.6 GO:0031529 ruffle organization(GO:0031529)
0.3 3.2 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.3 0.9 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.3 3.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.3 1.4 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.3 8.0 GO:0061718 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 2.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.3 1.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.3 3.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 6.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.3 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.3 0.8 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.3 0.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 1.6 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 1.0 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.3 3.1 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.3 1.5 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.3 1.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.2 1.2 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.2 0.5 GO:0032462 regulation of protein homooligomerization(GO:0032462)
0.2 0.5 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.2 2.4 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.2 2.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.7 GO:0071236 cellular response to antibiotic(GO:0071236)
0.2 0.7 GO:0019417 sulfur oxidation(GO:0019417)
0.2 0.9 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 0.7 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.4 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.2 0.9 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 4.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.6 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.2 1.3 GO:1903027 regulation of opsonization(GO:1903027)
0.2 0.6 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.2 6.2 GO:0031100 organ regeneration(GO:0031100)
0.2 0.8 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 1.6 GO:1902930 regulation of alcohol biosynthetic process(GO:1902930)
0.2 0.6 GO:0051697 protein delipidation(GO:0051697)
0.2 5.2 GO:1903578 regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.2 3.6 GO:0001541 ovarian follicle development(GO:0001541)
0.2 0.4 GO:0051352 negative regulation of ligase activity(GO:0051352)
0.2 2.4 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.2 0.7 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.5 GO:0072718 response to cisplatin(GO:0072718)
0.2 3.2 GO:0045214 sarcomere organization(GO:0045214)
0.2 0.5 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.2 1.2 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.2 4.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 0.8 GO:0001782 B cell homeostasis(GO:0001782)
0.2 0.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 2.9 GO:0006491 N-glycan processing(GO:0006491)
0.2 2.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.0 GO:0045730 respiratory burst(GO:0045730)
0.1 2.2 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.1 1.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.5 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.3 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.1 1.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 1.0 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 0.2 GO:0010517 regulation of phospholipase activity(GO:0010517)
0.1 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.6 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.6 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.7 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 2.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 2.7 GO:0060416 response to growth hormone(GO:0060416)
0.1 0.9 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.0 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.1 1.1 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.2 GO:1904350 regulation of protein catabolic process in the vacuole(GO:1904350)
0.1 0.6 GO:0030421 defecation(GO:0030421)
0.1 0.5 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 2.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 10.4 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 0.8 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.1 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0030879 mammary gland development(GO:0030879)
0.1 0.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.9 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.1 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.4 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.1 GO:0019532 oxalate transport(GO:0019532)
0.1 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.4 GO:0045064 T-helper 2 cell differentiation(GO:0045064)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0 0.3 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776) retinal metabolic process(GO:0042574)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.2 GO:0060548 negative regulation of cell death(GO:0060548)
0.0 0.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
97.6 292.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
55.7 446.0 GO:0005683 U7 snRNP(GO:0005683)
55.5 499.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
46.3 185.1 GO:0070985 TFIIK complex(GO:0070985)
40.3 161.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
39.0 273.3 GO:0034709 methylosome(GO:0034709)
37.2 185.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
36.5 437.4 GO:0031595 nuclear proteasome complex(GO:0031595)
36.1 180.3 GO:0097149 centralspindlin complex(GO:0097149)
34.6 207.5 GO:0071817 MMXD complex(GO:0071817)
32.7 424.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
32.1 192.6 GO:1902560 GMP reductase complex(GO:1902560)
29.5 147.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
29.4 58.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
29.2 145.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
28.8 172.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
28.4 199.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
28.1 84.3 GO:0018444 translation release factor complex(GO:0018444)
27.0 108.0 GO:0005846 nuclear cap binding complex(GO:0005846)
26.9 242.1 GO:0072546 ER membrane protein complex(GO:0072546)
25.2 252.4 GO:0000796 condensin complex(GO:0000796)
24.9 124.7 GO:0032021 NELF complex(GO:0032021)
24.8 124.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
24.8 24.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
23.9 71.7 GO:0034455 t-UTP complex(GO:0034455)
23.2 255.6 GO:0005688 U6 snRNP(GO:0005688)
23.0 184.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
22.7 203.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
22.5 696.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
22.1 242.9 GO:0005838 proteasome regulatory particle(GO:0005838)
21.8 261.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
21.4 85.6 GO:0071001 U4/U6 snRNP(GO:0071001)
21.1 190.1 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
21.1 168.5 GO:0032133 chromosome passenger complex(GO:0032133)
21.1 105.3 GO:0071986 Ragulator complex(GO:0071986)
20.8 166.2 GO:1990111 spermatoproteasome complex(GO:1990111)
19.8 59.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
19.3 231.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
19.2 364.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
18.3 329.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
18.2 72.7 GO:0044611 nuclear pore inner ring(GO:0044611)
18.1 272.2 GO:0005686 U2 snRNP(GO:0005686)
17.6 88.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
17.4 52.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
17.4 69.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
17.3 103.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
17.3 86.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
17.3 69.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
16.8 134.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
16.7 267.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
16.6 133.1 GO:0070552 BRISC complex(GO:0070552)
16.5 263.5 GO:0031080 nuclear pore outer ring(GO:0031080)
16.3 114.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
15.6 109.5 GO:0016272 prefoldin complex(GO:0016272)
15.1 45.4 GO:0097441 basilar dendrite(GO:0097441)
15.0 150.1 GO:0097255 R2TP complex(GO:0097255)
14.8 103.6 GO:0005787 signal peptidase complex(GO:0005787)
14.7 44.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
14.5 29.1 GO:0000930 gamma-tubulin complex(GO:0000930)
14.5 43.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
14.4 130.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
14.4 173.2 GO:0030008 TRAPP complex(GO:0030008)
14.2 14.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
13.8 41.5 GO:0071159 NF-kappaB complex(GO:0071159)
13.7 41.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
13.6 285.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
13.5 94.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
13.3 92.9 GO:0031298 replication fork protection complex(GO:0031298)
13.1 65.6 GO:0071797 LUBAC complex(GO:0071797)
13.1 52.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
13.0 495.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
13.0 38.9 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
12.9 347.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
12.8 128.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
12.8 25.5 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
12.7 76.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
12.5 62.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
12.5 62.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
12.4 86.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
12.4 37.2 GO:0031262 Ndc80 complex(GO:0031262)
12.3 37.0 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
12.2 183.6 GO:0005662 DNA replication factor A complex(GO:0005662)
12.1 60.3 GO:0042643 actomyosin, actin portion(GO:0042643)
12.0 84.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
12.0 47.9 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
11.9 71.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
11.8 129.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
11.7 46.9 GO:0031417 NatC complex(GO:0031417)
11.6 162.0 GO:0001673 male germ cell nucleus(GO:0001673)
11.6 34.7 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
11.5 103.9 GO:0000439 core TFIIH complex(GO:0000439)
11.5 45.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
11.0 77.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
11.0 517.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
10.9 54.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
10.8 129.9 GO:0042555 MCM complex(GO:0042555)
10.7 118.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
10.7 32.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
10.6 31.7 GO:1902636 kinociliary basal body(GO:1902636)
10.5 42.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
10.4 62.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
10.3 41.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
10.3 51.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
9.9 49.7 GO:1990425 ryanodine receptor complex(GO:1990425)
9.8 68.9 GO:0061617 MICOS complex(GO:0061617)
9.8 29.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
9.8 68.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
9.6 38.6 GO:1990423 RZZ complex(GO:1990423)
9.6 38.2 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
9.5 170.5 GO:0030686 90S preribosome(GO:0030686)
9.5 113.6 GO:0032040 small-subunit processome(GO:0032040)
9.4 37.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
8.9 542.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
8.9 958.6 GO:0015934 large ribosomal subunit(GO:0015934)
8.8 8.8 GO:0070761 pre-snoRNP complex(GO:0070761)
8.7 121.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
8.6 163.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
8.6 25.7 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
8.4 33.7 GO:0032044 DSIF complex(GO:0032044)
8.3 50.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
8.2 49.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
8.1 227.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
8.1 32.3 GO:0070876 SOSS complex(GO:0070876)
7.9 31.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
7.9 142.7 GO:0005685 U1 snRNP(GO:0005685)
7.9 78.8 GO:0030126 COPI vesicle coat(GO:0030126)
7.6 22.9 GO:0001940 male pronucleus(GO:0001940)
7.5 269.2 GO:0090544 BAF-type complex(GO:0090544)
7.5 186.7 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
7.4 44.2 GO:0008537 proteasome activator complex(GO:0008537)
7.3 73.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
7.3 14.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
7.2 50.4 GO:0031415 NatA complex(GO:0031415)
7.1 57.2 GO:0042382 paraspeckles(GO:0042382)
7.1 49.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
7.1 317.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
7.0 70.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
7.0 90.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
6.9 20.8 GO:0061700 GATOR2 complex(GO:0061700)
6.8 75.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
6.8 27.2 GO:0005839 proteasome core complex(GO:0005839)
6.8 447.8 GO:0015935 small ribosomal subunit(GO:0015935)
6.7 53.7 GO:0000322 storage vacuole(GO:0000322)
6.7 6.7 GO:0016328 lateral plasma membrane(GO:0016328)
6.6 305.2 GO:0008180 COP9 signalosome(GO:0008180)
6.5 19.6 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
6.5 26.0 GO:0032301 MutSalpha complex(GO:0032301)
6.3 182.9 GO:0005680 anaphase-promoting complex(GO:0005680)
6.3 25.2 GO:0097452 GAIT complex(GO:0097452)
6.3 112.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
6.1 146.2 GO:0036452 ESCRT complex(GO:0036452)
6.0 35.9 GO:0070435 Shc-EGFR complex(GO:0070435)
5.9 29.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
5.8 261.0 GO:0005840 ribosome(GO:0005840)
5.7 34.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
5.7 17.2 GO:0034680 integrin alpha1-beta1 complex(GO:0034665) integrin alpha3-beta1 complex(GO:0034667) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680)
5.7 107.7 GO:0036020 endolysosome membrane(GO:0036020)
5.3 15.9 GO:0005873 plus-end kinesin complex(GO:0005873)
5.3 21.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
5.2 20.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
5.2 20.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
5.1 10.2 GO:0070939 Dsl1p complex(GO:0070939)
5.0 40.0 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
4.9 34.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
4.9 29.4 GO:0061689 tricellular tight junction(GO:0061689)
4.8 61.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
4.7 75.2 GO:0000812 Swr1 complex(GO:0000812)
4.7 41.9 GO:0090543 Flemming body(GO:0090543)
4.6 78.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
4.6 22.9 GO:0035061 interchromatin granule(GO:0035061)
4.5 13.6 GO:0030684 preribosome(GO:0030684)
4.5 345.7 GO:0005643 nuclear pore(GO:0005643)
4.4 39.8 GO:0043203 axon hillock(GO:0043203)
4.4 53.0 GO:0017119 Golgi transport complex(GO:0017119)
4.4 13.2 GO:1990393 3M complex(GO:1990393)
4.4 26.1 GO:0001740 Barr body(GO:0001740)
4.3 39.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
4.3 25.9 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
4.3 8.6 GO:0070557 PCNA-p21 complex(GO:0070557)
4.3 21.4 GO:0043601 nuclear replisome(GO:0043601)
4.2 25.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
4.2 50.7 GO:0030127 COPII vesicle coat(GO:0030127)
4.2 618.7 GO:0005681 spliceosomal complex(GO:0005681)
4.2 33.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
4.2 4.2 GO:0098857 membrane microdomain(GO:0098857)
4.1 215.0 GO:0005871 kinesin complex(GO:0005871)
4.1 49.1 GO:0097433 dense body(GO:0097433)
3.9 31.2 GO:0042405 nuclear inclusion body(GO:0042405)
3.9 42.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
3.8 11.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
3.8 19.0 GO:0070187 telosome(GO:0070187)
3.8 11.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
3.7 74.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
3.7 33.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
3.5 14.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
3.5 51.9 GO:0005641 nuclear envelope lumen(GO:0005641)
3.4 20.6 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
3.4 10.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
3.4 16.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
3.3 23.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
3.2 16.2 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
3.2 35.2 GO:0070765 gamma-secretase complex(GO:0070765)
3.1 25.1 GO:0001739 sex chromatin(GO:0001739)
3.1 15.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
3.1 6.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
3.0 29.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
3.0 238.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
2.9 8.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.9 192.8 GO:0005637 nuclear inner membrane(GO:0005637)
2.9 285.8 GO:0017053 transcriptional repressor complex(GO:0017053)
2.8 11.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
2.7 35.5 GO:0031209 SCAR complex(GO:0031209)
2.7 8.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
2.7 10.9 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
2.7 42.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
2.6 13.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
2.6 38.4 GO:0005876 spindle microtubule(GO:0005876)
2.5 30.1 GO:0016461 unconventional myosin complex(GO:0016461)
2.5 39.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
2.4 22.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
2.4 36.5 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
2.4 60.1 GO:0045171 intercellular bridge(GO:0045171)
2.4 31.1 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
2.4 169.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
2.3 4.7 GO:0005826 actomyosin contractile ring(GO:0005826)
2.3 25.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
2.3 25.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
2.3 7.0 GO:0005607 laminin-2 complex(GO:0005607)
2.3 18.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
2.3 9.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
2.2 51.6 GO:0032156 septin cytoskeleton(GO:0032156)
2.2 15.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.2 11.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
2.2 6.6 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
2.2 100.4 GO:0016235 aggresome(GO:0016235)
2.1 6.4 GO:0031523 Myb complex(GO:0031523)
2.1 10.5 GO:0016589 NURF complex(GO:0016589)
2.1 10.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
2.1 6.2 GO:0032432 actin filament bundle(GO:0032432)
2.1 6.2 GO:0030870 Mre11 complex(GO:0030870)
2.0 8.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
2.0 18.4 GO:0070652 HAUS complex(GO:0070652)
2.0 6.1 GO:0005955 calcineurin complex(GO:0005955)
2.0 6.0 GO:0070578 RISC-loading complex(GO:0070578)
2.0 17.9 GO:0070419 nonhomologous end joining complex(GO:0070419)
2.0 112.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
2.0 283.0 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
1.9 7.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.9 42.6 GO:0000502 proteasome complex(GO:0000502)
1.9 7.7 GO:0000109 nucleotide-excision repair complex(GO:0000109)
1.9 24.9 GO:0005844 polysome(GO:0005844)
1.9 3.8 GO:0031201 SNARE complex(GO:0031201)
1.9 5.7 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
1.9 1.9 GO:0044393 microspike(GO:0044393)
1.8 25.9 GO:0032433 filopodium tip(GO:0032433)
1.8 14.8 GO:0032039 integrator complex(GO:0032039)
1.8 23.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.8 1.8 GO:0000346 transcription export complex(GO:0000346)
1.8 29.8 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.7 36.1 GO:0030125 clathrin vesicle coat(GO:0030125)
1.7 76.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
1.7 91.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.7 217.6 GO:0000793 condensed chromosome(GO:0000793)
1.6 4.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
1.6 35.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
1.6 22.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
1.6 9.5 GO:0044754 autolysosome(GO:0044754)
1.6 4.7 GO:0005588 collagen type V trimer(GO:0005588)
1.6 9.4 GO:1990357 terminal web(GO:1990357)
1.6 10.9 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
1.6 119.4 GO:0035578 azurophil granule lumen(GO:0035578)
1.5 6.1 GO:0098800 inner mitochondrial membrane protein complex(GO:0098800)
1.5 4.5 GO:0002081 outer acrosomal membrane(GO:0002081)
1.4 4.3 GO:0000776 kinetochore(GO:0000776)
1.4 29.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.4 13.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
1.4 23.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
1.4 117.4 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
1.4 1.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
1.3 10.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
1.3 46.9 GO:0031258 lamellipodium membrane(GO:0031258)
1.3 19.2 GO:0005814 centriole(GO:0005814)
1.3 8.9 GO:0097209 epidermal lamellar body(GO:0097209)
1.3 3.8 GO:0019008 molybdopterin synthase complex(GO:0019008)
1.3 7.5 GO:0044327 dendritic spine head(GO:0044327)
1.2 126.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
1.2 24.8 GO:0030904 retromer complex(GO:0030904)
1.2 383.1 GO:0005635 nuclear envelope(GO:0005635)
1.2 105.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
1.2 163.1 GO:0031968 organelle outer membrane(GO:0031968)
1.1 11.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.1 7.8 GO:0044292 dendrite terminus(GO:0044292)
1.1 6.6 GO:0071203 WASH complex(GO:0071203)
1.1 2.2 GO:0097431 mitotic spindle pole(GO:0097431)
1.1 11.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.1 4.2 GO:0032449 CBM complex(GO:0032449)
1.0 131.6 GO:0005795 Golgi stack(GO:0005795)
1.0 5.2 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
1.0 4.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.0 34.0 GO:0035577 azurophil granule membrane(GO:0035577)
1.0 19.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.0 2.9 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.0 224.1 GO:0019866 organelle inner membrane(GO:0019866)
1.0 4.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.9 9.3 GO:0042641 actomyosin(GO:0042641)
0.9 924.3 GO:0005739 mitochondrion(GO:0005739)
0.9 5.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.8 14.1 GO:0031941 filamentous actin(GO:0031941)
0.8 1.6 GO:0033186 CAF-1 complex(GO:0033186)
0.8 17.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.8 7.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.8 2.3 GO:1990130 Iml1 complex(GO:1990130)
0.8 9.4 GO:0031932 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.8 10.1 GO:0070822 Sin3-type complex(GO:0070822)
0.8 2.3 GO:0031264 death-inducing signaling complex(GO:0031264)
0.8 3.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.8 7.6 GO:0005614 interstitial matrix(GO:0005614)
0.7 1.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.7 1.4 GO:0097470 ribbon synapse(GO:0097470)
0.7 4.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.7 0.7 GO:0032302 MutSbeta complex(GO:0032302)
0.7 0.7 GO:0001652 granular component(GO:0001652)
0.7 107.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.7 3.9 GO:0072687 meiotic spindle(GO:0072687)
0.6 4.4 GO:0043204 perikaryon(GO:0043204)
0.6 6.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.6 3.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.6 11.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.6 13.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.6 9.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 1.7 GO:0000145 exocyst(GO:0000145)
0.6 64.6 GO:0043197 dendritic spine(GO:0043197)
0.6 15.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.6 5.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.6 10.5 GO:0031528 microvillus membrane(GO:0031528)
0.5 3.8 GO:0097443 sorting endosome(GO:0097443)
0.5 2.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.5 3.6 GO:0032059 bleb(GO:0032059)
0.5 3.6 GO:0061702 inflammasome complex(GO:0061702)
0.5 3.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.5 1.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.5 10.6 GO:0031526 brush border membrane(GO:0031526)
0.5 16.4 GO:0030175 filopodium(GO:0030175)
0.4 3.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 10.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.4 0.9 GO:0043219 lateral loop(GO:0043219)
0.4 7.6 GO:0045178 basal part of cell(GO:0045178)
0.4 6.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 0.8 GO:0051286 cell tip(GO:0051286)
0.4 4.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.4 6.9 GO:0002102 podosome(GO:0002102)
0.4 1.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 0.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 743.7 GO:0070062 extracellular exosome(GO:0070062)
0.3 13.3 GO:0035579 specific granule membrane(GO:0035579)
0.3 0.9 GO:0042587 glycogen granule(GO:0042587)
0.3 1.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 3.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.3 1.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 2.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 2.6 GO:0001772 immunological synapse(GO:0001772)
0.2 3.3 GO:0043034 costamere(GO:0043034)
0.2 3.5 GO:0099503 secretory vesicle(GO:0099503)
0.2 1.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.0 GO:0033263 CORVET complex(GO:0033263)
0.2 10.9 GO:0031091 platelet alpha granule(GO:0031091)
0.2 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.2 0.8 GO:0043196 varicosity(GO:0043196)
0.2 0.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 0.3 GO:0071437 invadopodium(GO:0071437)
0.2 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 3.0 GO:0032994 protein-lipid complex(GO:0032994)
0.1 1.0 GO:0001726 ruffle(GO:0001726)
0.1 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 1.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
97.6 292.9 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
73.1 219.4 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
43.3 216.5 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
40.8 122.4 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
40.0 120.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
38.2 382.3 GO:0070990 snRNP binding(GO:0070990)
36.9 110.7 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
36.1 252.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
34.6 138.4 GO:0032217 riboflavin transporter activity(GO:0032217)
34.2 68.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
33.4 367.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
32.9 197.4 GO:0030621 U4 snRNA binding(GO:0030621)
32.7 98.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
32.1 192.6 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
32.0 159.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
31.3 94.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
29.1 87.3 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
28.4 142.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
26.9 268.9 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
26.1 130.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
26.1 78.3 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
24.3 72.9 GO:0017130 poly(C) RNA binding(GO:0017130)
24.2 121.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
24.2 169.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
23.3 70.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
23.0 138.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
22.0 242.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
21.7 65.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
21.6 43.3 GO:0008312 7S RNA binding(GO:0008312)
20.8 207.7 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
20.7 455.7 GO:0000339 RNA cap binding(GO:0000339)
19.8 59.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
19.5 584.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
18.4 91.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
18.4 36.8 GO:0003998 acylphosphatase activity(GO:0003998)
18.4 73.4 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
18.3 54.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
18.3 329.3 GO:0001054 RNA polymerase I activity(GO:0001054)
18.1 162.9 GO:0035174 histone serine kinase activity(GO:0035174)
18.1 54.2 GO:0005047 signal recognition particle binding(GO:0005047)
17.3 103.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
17.3 69.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
16.7 100.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
16.4 98.5 GO:0042296 ISG15 transferase activity(GO:0042296)
16.4 212.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
16.2 113.4 GO:0030620 U2 snRNA binding(GO:0030620)
15.9 47.8 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
15.8 47.4 GO:0030984 kininogen binding(GO:0030984)
15.7 157.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
15.5 61.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
15.2 45.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
15.2 45.6 GO:0034511 U3 snoRNA binding(GO:0034511)
14.5 58.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
14.4 43.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
14.3 71.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
14.3 71.4 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
14.2 767.8 GO:0003743 translation initiation factor activity(GO:0003743)
14.2 113.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
14.1 42.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
13.9 69.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
13.8 41.4 GO:0004170 dUTP diphosphatase activity(GO:0004170)
13.5 54.0 GO:0016748 succinyltransferase activity(GO:0016748)
13.5 53.9 GO:0005046 KDEL sequence binding(GO:0005046)
13.0 39.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
13.0 51.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
12.8 51.3 GO:0002060 purine nucleobase binding(GO:0002060)
12.8 102.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
12.7 203.5 GO:0004526 ribonuclease P activity(GO:0004526)
12.7 89.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
12.7 76.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
12.6 12.6 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
12.6 75.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
12.3 86.4 GO:0050815 phosphoserine binding(GO:0050815)
12.2 36.5 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
12.1 36.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
12.1 156.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
12.0 108.3 GO:1901612 cardiolipin binding(GO:1901612)
11.9 630.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
11.8 47.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
11.7 93.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
11.7 46.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
11.7 339.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
11.5 23.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
11.4 171.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
11.3 79.2 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
11.3 67.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
11.1 144.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
11.0 252.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
10.8 75.9 GO:0061133 endopeptidase activator activity(GO:0061133)
10.7 106.7 GO:0019237 centromeric DNA binding(GO:0019237)
10.5 21.0 GO:0004017 adenylate kinase activity(GO:0004017)
10.3 31.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
10.3 61.9 GO:0019238 cyclohydrolase activity(GO:0019238)
10.2 40.9 GO:0016531 copper chaperone activity(GO:0016531)
10.1 364.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
10.0 50.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
9.9 119.1 GO:0030515 snoRNA binding(GO:0030515)
9.9 49.6 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
9.9 29.7 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
9.9 138.8 GO:0016018 cyclosporin A binding(GO:0016018)
9.9 148.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
9.8 29.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
9.8 39.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
9.6 96.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
9.5 66.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
9.4 37.7 GO:0004774 succinate-CoA ligase activity(GO:0004774)
9.4 37.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
9.4 74.9 GO:0097100 supercoiled DNA binding(GO:0097100)
9.1 1929.8 GO:0003735 structural constituent of ribosome(GO:0003735)
9.0 9.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
9.0 36.0 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
8.9 26.8 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
8.9 8.9 GO:0019961 interferon binding(GO:0019961)
8.6 51.6 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
8.6 25.8 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
8.5 25.5 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
8.5 25.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
8.4 50.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
8.3 8.3 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
8.2 24.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
8.1 841.0 GO:0003697 single-stranded DNA binding(GO:0003697)
8.1 40.4 GO:0008097 5S rRNA binding(GO:0008097)
8.0 95.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
7.9 31.5 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
7.9 31.5 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
7.8 23.5 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
7.8 23.5 GO:0017070 U6 snRNA binding(GO:0017070)
7.8 31.0 GO:0048256 flap endonuclease activity(GO:0048256)
7.7 46.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
7.7 15.4 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
7.7 23.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
7.7 7.7 GO:0048038 quinone binding(GO:0048038)
7.7 30.7 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
7.5 15.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
7.5 22.5 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
7.5 22.4 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
7.5 67.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
7.4 29.5 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
7.3 36.7 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
7.3 7.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
7.1 114.3 GO:0008266 poly(U) RNA binding(GO:0008266)
7.1 148.8 GO:0042609 CD4 receptor binding(GO:0042609)
7.1 7.1 GO:0030145 manganese ion binding(GO:0030145)
7.0 70.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
6.9 27.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
6.9 103.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
6.9 6.9 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
6.8 13.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
6.8 121.9 GO:0043495 protein anchor(GO:0043495)
6.8 67.6 GO:0031386 protein tag(GO:0031386)
6.8 148.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
6.7 74.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
6.7 46.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
6.7 20.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
6.6 6.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
6.6 6.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
6.5 13.0 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
6.5 156.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
6.5 45.5 GO:1990226 histone methyltransferase binding(GO:1990226)
6.5 279.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
6.5 25.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
6.4 25.5 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
6.2 37.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
6.2 37.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
6.2 154.5 GO:0070182 DNA polymerase binding(GO:0070182)
6.1 49.0 GO:0016842 amidine-lyase activity(GO:0016842)
6.0 163.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
6.0 24.0 GO:0004348 glucosylceramidase activity(GO:0004348)
6.0 35.9 GO:0048408 epidermal growth factor binding(GO:0048408)
6.0 179.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
6.0 6.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
5.8 46.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
5.7 28.7 GO:0002046 opsin binding(GO:0002046)
5.7 97.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
5.6 56.2 GO:0001055 RNA polymerase II activity(GO:0001055)
5.6 16.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
5.6 22.3 GO:0004594 pantothenate kinase activity(GO:0004594)
5.4 168.9 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
5.4 10.7 GO:0000182 rDNA binding(GO:0000182)
5.3 16.0 GO:0001069 regulatory region RNA binding(GO:0001069)
5.3 15.8 GO:0032184 SUMO polymer binding(GO:0032184)
5.2 36.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
5.2 51.7 GO:0042731 PH domain binding(GO:0042731)
5.1 15.3 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
5.0 10.0 GO:0042979 ornithine decarboxylase activator activity(GO:0042978) ornithine decarboxylase regulator activity(GO:0042979)
5.0 19.9 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
5.0 5.0 GO:0051731 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
5.0 29.7 GO:0035500 MH2 domain binding(GO:0035500)
4.9 24.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
4.9 58.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
4.8 19.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
4.8 14.4 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
4.8 14.3 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
4.8 81.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
4.8 19.0 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
4.7 19.0 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
4.7 198.9 GO:0050699 WW domain binding(GO:0050699)
4.7 28.3 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
4.7 14.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
4.7 211.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
4.7 28.0 GO:0015266 protein channel activity(GO:0015266)
4.6 157.5 GO:0051059 NF-kappaB binding(GO:0051059)
4.6 73.5 GO:0032036 myosin heavy chain binding(GO:0032036)
4.6 54.7 GO:0089720 caspase binding(GO:0089720)
4.5 63.0 GO:0008179 adenylate cyclase binding(GO:0008179)
4.4 128.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
4.4 17.7 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
4.4 8.8 GO:0032137 guanine/thymine mispair binding(GO:0032137)
4.4 13.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
4.4 56.9 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
4.4 30.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
4.3 17.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
4.3 4.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
4.3 8.6 GO:0097677 STAT family protein binding(GO:0097677)
4.3 90.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
4.3 12.8 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
4.2 76.3 GO:0070628 proteasome binding(GO:0070628)
4.2 33.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
4.2 4.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
4.2 16.8 GO:0034186 apolipoprotein A-I binding(GO:0034186)
4.2 20.9 GO:0016829 lyase activity(GO:0016829)
4.2 146.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
4.2 133.4 GO:0001671 ATPase activator activity(GO:0001671)
4.1 109.6 GO:0070064 proline-rich region binding(GO:0070064)
4.0 52.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
4.0 12.1 GO:0032089 NACHT domain binding(GO:0032089)
4.0 44.2 GO:0019843 rRNA binding(GO:0019843)
4.0 39.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
4.0 15.8 GO:0004566 beta-glucuronidase activity(GO:0004566)
3.9 58.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
3.9 205.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
3.9 231.2 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
3.8 149.8 GO:0008536 Ran GTPase binding(GO:0008536)
3.8 30.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
3.8 11.4 GO:0004730 pseudouridylate synthase activity(GO:0004730)
3.8 11.4 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
3.8 3.8 GO:0019239 deaminase activity(GO:0019239)
3.8 64.0 GO:0000149 SNARE binding(GO:0000149)
3.7 22.5 GO:0004849 uridine kinase activity(GO:0004849)
3.7 33.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
3.7 18.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
3.7 11.0 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
3.7 58.6 GO:0031491 nucleosome binding(GO:0031491)
3.7 25.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
3.6 65.4 GO:0070717 poly-purine tract binding(GO:0070717)
3.6 162.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
3.6 7.2 GO:0008384 IkappaB kinase activity(GO:0008384)
3.6 3.6 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)
3.6 161.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
3.6 17.9 GO:0043120 tumor necrosis factor binding(GO:0043120)
3.6 21.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
3.6 7.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
3.5 10.6 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
3.5 7.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
3.5 76.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
3.5 55.3 GO:0097602 cullin family protein binding(GO:0097602)
3.4 10.2 GO:0036033 mediator complex binding(GO:0036033)
3.4 10.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
3.4 44.2 GO:0003688 DNA replication origin binding(GO:0003688)
3.4 16.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
3.4 73.8 GO:0008242 omega peptidase activity(GO:0008242)
3.3 6.7 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
3.3 20.0 GO:0019776 Atg8 ligase activity(GO:0019776)
3.3 23.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
3.3 16.5 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
3.3 16.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
3.3 22.8 GO:0000400 four-way junction DNA binding(GO:0000400)
3.2 45.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
3.2 9.6 GO:0031996 thioesterase binding(GO:0031996)
3.2 135.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
3.2 25.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
3.1 6.2 GO:0016882 cyclo-ligase activity(GO:0016882)
3.0 9.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
2.9 17.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
2.9 58.8 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
2.9 35.2 GO:0008327 methyl-CpG binding(GO:0008327)
2.9 58.4 GO:0005537 mannose binding(GO:0005537)
2.9 5.8 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
2.9 20.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.9 8.6 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
2.9 2.9 GO:0003678 DNA helicase activity(GO:0003678)
2.9 11.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
2.9 8.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
2.9 5.7 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
2.8 28.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
2.8 25.3 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
2.8 56.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
2.8 24.9 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
2.8 11.0 GO:0015140 malate transmembrane transporter activity(GO:0015140)
2.8 339.0 GO:0047485 protein N-terminus binding(GO:0047485)
2.8 11.0 GO:0004132 dCMP deaminase activity(GO:0004132)
2.7 21.9 GO:0015288 porin activity(GO:0015288)
2.7 8.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
2.7 148.7 GO:0019003 GDP binding(GO:0019003)
2.7 29.5 GO:0004312 fatty acid synthase activity(GO:0004312)
2.7 31.9 GO:0017049 GTP-Rho binding(GO:0017049)
2.7 5.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
2.7 21.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
2.7 10.6 GO:0043515 kinetochore binding(GO:0043515)
2.7 188.2 GO:0008565 protein transporter activity(GO:0008565)
2.6 89.1 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
2.6 106.3 GO:0004177 aminopeptidase activity(GO:0004177)
2.6 49.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
2.6 15.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
2.6 12.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
2.6 17.9 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
2.5 101.6 GO:0003725 double-stranded RNA binding(GO:0003725)
2.5 10.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
2.5 15.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
2.5 57.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
2.5 9.9 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
2.4 17.0 GO:0050733 RS domain binding(GO:0050733)
2.4 17.0 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
2.4 532.1 GO:0051015 actin filament binding(GO:0051015)
2.4 57.6 GO:0031489 myosin V binding(GO:0031489)
2.4 4.7 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
2.3 11.7 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
2.3 23.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
2.3 25.6 GO:0070840 dynein complex binding(GO:0070840)
2.3 107.7 GO:0003727 single-stranded RNA binding(GO:0003727)
2.3 43.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
2.3 13.7 GO:0008046 axon guidance receptor activity(GO:0008046)
2.2 6.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
2.2 184.0 GO:0051082 unfolded protein binding(GO:0051082)
2.2 15.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
2.2 13.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
2.2 4.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
2.2 17.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
2.1 8.6 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
2.1 4.3 GO:0016417 S-acyltransferase activity(GO:0016417)
2.1 57.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
2.1 192.6 GO:0043130 ubiquitin binding(GO:0043130)
2.1 8.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.1 25.1 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
2.1 8.3 GO:0003684 damaged DNA binding(GO:0003684)
2.1 6.2 GO:0070087 chromo shadow domain binding(GO:0070087)
2.1 6.2 GO:0016301 kinase activity(GO:0016301)
2.1 2.1 GO:0043566 structure-specific DNA binding(GO:0043566)
2.0 4.1 GO:0052724 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
2.0 4.1 GO:0051219 phosphoprotein binding(GO:0051219)
2.0 6.1 GO:1990254 keratin filament binding(GO:1990254)
2.0 6.1 GO:0005126 cytokine receptor binding(GO:0005126)
2.0 6.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.0 141.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
2.0 13.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.9 48.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.9 11.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.9 5.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.9 9.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
1.9 16.7 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
1.9 1.9 GO:0008174 mRNA methyltransferase activity(GO:0008174)
1.8 3.7 GO:0004167 dopachrome isomerase activity(GO:0004167)
1.8 11.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.8 88.8 GO:0003777 microtubule motor activity(GO:0003777)
1.8 18.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.8 9.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
1.8 10.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
1.8 5.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.8 17.7 GO:0019534 toxin transporter activity(GO:0019534)
1.7 5.2 GO:0033149 FFAT motif binding(GO:0033149)
1.7 7.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.7 12.0 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
1.7 5.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
1.7 23.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
1.6 3.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.6 8.2 GO:0004905 type I interferon receptor activity(GO:0004905)
1.6 1752.3 GO:0003723 RNA binding(GO:0003723)
1.6 6.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.6 1.6 GO:0030957 Tat protein binding(GO:0030957)
1.6 14.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
1.6 9.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.6 8.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
1.6 44.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
1.6 14.1 GO:0008158 hedgehog receptor activity(GO:0008158)
1.6 6.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
1.5 52.2 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
1.5 3.0 GO:0030346 protein phosphatase 2B binding(GO:0030346)
1.5 15.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
1.5 27.1 GO:0031404 chloride ion binding(GO:0031404)
1.5 5.9 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
1.5 10.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
1.4 13.0 GO:0032794 GTPase activating protein binding(GO:0032794)
1.4 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
1.4 15.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
1.4 8.5 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
1.4 5.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
1.3 9.4 GO:0043208 glycosphingolipid binding(GO:0043208)
1.3 8.0 GO:0031748 D1 dopamine receptor binding(GO:0031748)
1.3 17.3 GO:0004985 opioid receptor activity(GO:0004985)
1.3 9.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
1.3 31.3 GO:0005123 death receptor binding(GO:0005123)
1.3 5.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.3 5.2 GO:0004359 glutaminase activity(GO:0004359)
1.3 6.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.3 3.8 GO:0030366 molybdopterin synthase activity(GO:0030366)
1.3 5.0 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
1.2 1.2 GO:0097001 ceramide binding(GO:0097001)
1.2 3.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
1.2 27.2 GO:0051879 Hsp90 protein binding(GO:0051879)
1.2 259.0 GO:0003924 GTPase activity(GO:0003924)
1.2 3.6 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.2 8.5 GO:0045545 syndecan binding(GO:0045545)
1.2 1.2 GO:0051185 coenzyme transporter activity(GO:0051185)
1.2 49.2 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
1.2 7.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
1.2 1.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.2 29.2 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
1.1 11.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
1.1 4.6 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
1.1 23.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.1 9.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.1 2.1 GO:0038025 reelin receptor activity(GO:0038025)
1.1 3.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.0 7.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.0 3.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.0 5.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
1.0 9.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.0 3.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.0 14.7 GO:0004386 helicase activity(GO:0004386)
1.0 17.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.0 1.9 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.9 0.9 GO:0005124 scavenger receptor binding(GO:0005124)
0.9 6.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.9 4.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.9 4.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.9 2.7 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.9 0.9 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.9 4.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.9 4.3 GO:0097016 L27 domain binding(GO:0097016)
0.9 3.4 GO:0004046 aminoacylase activity(GO:0004046)
0.8 3.4 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.8 16.0 GO:0070410 co-SMAD binding(GO:0070410)
0.8 6.7 GO:1990763 arrestin family protein binding(GO:1990763)
0.8 4.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.8 3.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.8 3.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.8 1.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.8 18.3 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.8 8.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.8 1.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.8 3.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.8 13.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.8 16.6 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.7 26.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.7 10.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 28.3 GO:0019201 nucleotide kinase activity(GO:0019201)
0.7 5.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7 1.5 GO:0046790 virion binding(GO:0046790)
0.7 2.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.7 14.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.7 3.6 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.7 2.9 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.7 0.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.7 2.1 GO:0070326 lipase binding(GO:0035473) very-low-density lipoprotein particle receptor binding(GO:0070326)
0.7 2.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.7 3.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.7 19.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.7 2.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.7 7.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.7 7.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.7 9.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.7 11.4 GO:0051400 BH domain binding(GO:0051400)
0.7 0.7 GO:0015923 alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.7 8.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.7 64.9 GO:0042393 histone binding(GO:0042393)
0.6 39.5 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.6 1.9 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.6 1.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.6 0.6 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.6 3.8 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.6 17.1 GO:0003785 actin monomer binding(GO:0003785)
0.6 6.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.6 1.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.6 4.9 GO:0008432 JUN kinase binding(GO:0008432)
0.6 1.8 GO:0086078 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.6 15.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.6 4.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.6 33.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.6 13.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 2.2 GO:0046979 TAP2 binding(GO:0046979)
0.6 16.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.6 3.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.6 2.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.5 4.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.5 3.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.5 5.4 GO:0015232 heme transporter activity(GO:0015232)
0.5 2.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.5 9.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 1.5 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.5 3.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.5 3.5 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.5 1.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.5 1.4 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.5 2.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 3.7 GO:0000287 magnesium ion binding(GO:0000287)
0.5 1.8 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.5 9.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.4 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 7.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 2.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.4 3.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.4 1.8 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.4 12.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 1.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.4 4.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.4 3.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.4 15.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.4 0.8 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.4 1.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.4 11.9 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.4 2.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 4.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.4 2.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.4 1.4 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.4 11.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.4 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 39.3 GO:0005262 calcium channel activity(GO:0005262)
0.3 1.7 GO:0052742 phosphatidylinositol kinase activity(GO:0052742)
0.3 2.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 2.3 GO:0031402 sodium ion binding(GO:0031402)
0.3 9.8 GO:0005080 protein kinase C binding(GO:0005080)
0.3 1.6 GO:0032182 ubiquitin-like protein binding(GO:0032182)
0.3 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) phosphofructokinase activity(GO:0008443)
0.3 0.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.3 10.4 GO:0005507 copper ion binding(GO:0005507)
0.3 3.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.3 3.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.3 40.1 GO:0005178 integrin binding(GO:0005178)
0.3 4.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 2.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 1.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.3 0.9 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 0.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.2 7.5 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.9 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 2.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 1.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 1.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 0.9 GO:0016499 orexin receptor activity(GO:0016499)
0.2 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 3.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.4 GO:0046977 peptide antigen-transporting ATPase activity(GO:0015433) TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.2 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 0.8 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.8 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 0.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 4.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 8.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 10.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.2 1.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 0.3 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.2 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 0.6 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 6.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.5 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 5.2 GO:0015399 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 1.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.1 GO:0009881 photoreceptor activity(GO:0009881)
0.1 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 4.3 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
16.2 227.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
8.6 562.2 PID AURORA B PATHWAY Aurora B signaling
8.3 375.4 PID PLK1 PATHWAY PLK1 signaling events
7.7 472.1 PID ATR PATHWAY ATR signaling pathway
7.6 205.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
7.4 208.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
5.7 34.3 PID TRAIL PATHWAY TRAIL signaling pathway
5.5 201.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
5.3 195.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
5.0 216.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
5.0 627.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
5.0 114.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
4.7 167.5 PID BARD1 PATHWAY BARD1 signaling events
4.3 4.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
4.2 79.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
3.8 96.1 PID AURORA A PATHWAY Aurora A signaling
3.8 198.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
3.7 164.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
3.6 112.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
3.5 58.7 PID ALK2 PATHWAY ALK2 signaling events
3.0 26.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
2.9 63.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
2.8 229.4 PID E2F PATHWAY E2F transcription factor network
2.8 50.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
2.7 186.5 PID RAC1 PATHWAY RAC1 signaling pathway
2.6 100.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
2.6 54.2 PID ARF 3PATHWAY Arf1 pathway
2.6 64.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
2.5 88.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
2.5 78.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
2.5 32.7 PID S1P S1P4 PATHWAY S1P4 pathway
2.3 53.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
2.1 8.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
2.1 53.9 PID CD40 PATHWAY CD40/CD40L signaling
2.1 61.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
1.7 97.6 PID ILK PATHWAY Integrin-linked kinase signaling
1.7 10.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
1.7 33.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
1.7 31.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
1.6 30.8 PID INSULIN PATHWAY Insulin Pathway
1.5 51.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
1.2 29.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
1.1 15.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
1.1 46.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.1 35.8 PID IL1 PATHWAY IL1-mediated signaling events
1.1 24.7 PID ALK1 PATHWAY ALK1 signaling events
1.0 63.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
1.0 38.0 PID EPHB FWD PATHWAY EPHB forward signaling
1.0 19.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
1.0 26.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.0 22.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.9 3.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.9 4.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.9 1.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.9 11.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.9 43.5 PID P73PATHWAY p73 transcription factor network
0.8 5.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.8 69.9 PID CMYB PATHWAY C-MYB transcription factor network
0.8 46.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.8 40.0 PID NOTCH PATHWAY Notch signaling pathway
0.8 27.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.7 10.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.7 94.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.7 26.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.7 14.6 PID FOXO PATHWAY FoxO family signaling
0.6 5.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.6 1.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.5 6.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.5 3.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.5 2.7 PID IFNG PATHWAY IFN-gamma pathway
0.5 21.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 12.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.4 1.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.4 27.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.4 10.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 8.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 8.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 14.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.3 3.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.3 6.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.3 5.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 5.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 1.8 PID IL3 PATHWAY IL3-mediated signaling events
0.2 0.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 4.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 6.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.0 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
33.9 541.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
29.2 145.8 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
27.6 248.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
24.6 122.8 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
20.6 1524.4 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
20.5 348.8 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
19.2 306.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
18.5 664.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
18.0 432.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
15.9 621.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
14.5 217.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
14.4 1093.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
14.3 256.7 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
14.2 14.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
13.8 757.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
13.1 431.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
12.6 214.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
12.5 200.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
12.4 24.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
12.4 123.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
12.2 195.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
12.0 179.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
11.5 287.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
11.4 1533.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
11.4 227.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
11.1 289.4 REACTOME KINESINS Genes involved in Kinesins
10.0 80.3 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
9.7 329.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
9.7 154.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
9.6 38.3 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
9.4 798.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
9.3 194.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
9.1 9.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
8.8 536.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
8.4 83.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
8.0 128.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
7.2 79.7 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
7.2 14.5 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
7.1 120.4 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
6.9 76.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
6.9 6.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
6.9 102.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
6.8 128.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
6.6 106.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
6.6 675.8 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
6.5 58.4 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
6.3 270.7 REACTOME TRANSLATION Genes involved in Translation
5.9 146.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
5.6 101.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
5.2 73.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
5.1 76.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
4.9 123.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
4.6 100.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
4.6 41.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
4.2 139.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
4.1 57.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
4.0 91.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
4.0 111.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
4.0 47.5 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
3.9 74.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
3.9 108.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
3.8 50.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
3.8 69.1 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
3.8 60.7 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
3.8 105.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
3.7 67.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
3.5 180.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
3.3 46.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
3.3 98.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
3.2 474.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
3.0 72.6 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
2.9 51.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
2.8 98.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
2.8 53.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
2.8 122.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
2.8 91.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
2.7 73.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
2.6 91.9 REACTOME G1 PHASE Genes involved in G1 Phase
2.6 67.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
2.6 23.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
2.6 97.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
2.5 17.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
2.5 72.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
2.4 69.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
2.4 54.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
2.3 11.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
2.3 18.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
2.3 20.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
2.2 6.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
2.2 83.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
2.2 44.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
2.1 52.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
2.1 37.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
2.1 64.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
2.1 41.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
2.1 72.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
2.1 20.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
2.1 61.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
2.0 32.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
2.0 87.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
2.0 45.7 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
1.9 50.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
1.8 3.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
1.8 85.8 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
1.7 15.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
1.7 8.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
1.6 45.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.5 39.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.5 10.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
1.5 30.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
1.5 30.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.4 19.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.4 67.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.3 18.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.3 9.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
1.2 11.0 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
1.1 6.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
1.1 14.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
1.1 5.3 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
1.0 4.9 REACTOME METABOLISM OF NUCLEOTIDES Genes involved in Metabolism of nucleotides
1.0 5.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
1.0 63.7 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.9 3.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.9 51.8 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
0.9 2.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.8 14.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.8 25.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.8 5.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.8 10.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.7 6.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.7 11.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.7 1.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.7 6.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.7 25.6 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.7 14.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.6 18.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.6 66.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.6 12.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 7.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.5 1.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.5 10.2 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.4 5.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.4 12.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 7.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4 1.8 REACTOME G1 S TRANSITION Genes involved in G1/S Transition
0.4 2.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.4 21.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 14.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 27.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 12.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 4.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 5.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 4.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 2.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 3.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 10.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 2.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.2 3.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 11.9 REACTOME METABOLISM OF PROTEINS Genes involved in Metabolism of proteins
0.2 3.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 3.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 2.7 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1 0.1 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 1.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 3.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 8.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols