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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for EN1_ESX1_GBX1

Z-value: 0.79

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Transcription factors associated with EN1_ESX1_GBX1

Gene Symbol Gene ID Gene Info
ENSG00000163064.6 engrailed homeobox 1
ENSG00000123576.5 ESX homeobox 1
ENSG00000164900.4 gastrulation brain homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GBX1hg19_v2_chr7_-_150864635_150864785-0.194.5e-03Click!
EN1hg19_v2_chr2_-_119605253_1196052640.186.3e-03Click!

Activity profile of EN1_ESX1_GBX1 motif

Sorted Z-values of EN1_ESX1_GBX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_111794446 32.90 ENST00000527950.1
crystallin, alpha B
chrX_-_13835147 28.51 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr3_+_111718036 27.74 ENST00000455401.2
transgelin 3
chr3_+_111718173 25.42 ENST00000494932.1
transgelin 3
chr3_+_111717600 25.31 ENST00000273368.4
transgelin 3
chr3_+_111717511 24.32 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr3_+_115342349 22.62 ENST00000393780.3
growth associated protein 43
chr11_-_117747434 21.52 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr11_-_117747607 21.49 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr12_-_6233828 21.46 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr11_-_117748138 21.40 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr7_+_100136811 18.86 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr16_+_58283814 17.84 ENST00000443128.2
ENST00000219299.4
coiled-coil domain containing 113
chr12_-_16759711 17.29 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr19_-_7968427 17.14 ENST00000539278.1
Uncharacterized protein
chr5_+_66300446 15.28 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr10_-_93392811 14.56 ENST00000238994.5
protein phosphatase 1, regulatory subunit 3C
chr1_-_118472216 13.82 ENST00000369443.5
ganglioside induced differentiation associated protein 2
chr12_+_81110684 13.59 ENST00000228644.3
myogenic factor 5
chr1_+_160160283 13.48 ENST00000368079.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr2_-_224467093 12.76 ENST00000305409.2
secretogranin II
chr12_+_7014064 12.44 ENST00000443597.2
leucine rich repeat containing 23
chr13_-_67802549 12.13 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr4_-_134070250 12.06 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
chr6_+_153552455 11.92 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr1_-_151762943 11.76 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
tudor and KH domain containing
chr8_+_105235572 11.72 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr1_+_160160346 11.53 ENST00000368078.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr12_+_7013897 11.52 ENST00000007969.8
ENST00000323702.5
leucine rich repeat containing 23
chr12_+_26348246 11.34 ENST00000422622.2
sarcospan
chr14_+_104182061 10.33 ENST00000216602.6
zinc finger, FYVE domain containing 21
chr14_+_104182105 10.27 ENST00000311141.2
zinc finger, FYVE domain containing 21
chr11_+_94706973 10.04 ENST00000536741.1
lysine (K)-specific demethylase 4D
chr16_-_29910853 9.96 ENST00000308713.5
seizure related 6 homolog (mouse)-like 2
chr4_-_8873531 9.74 ENST00000400677.3
H6 family homeobox 1
chr14_-_104181771 9.71 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
X-ray repair complementing defective repair in Chinese hamster cells 3
chr11_-_128894053 9.66 ENST00000392657.3
Rho GTPase activating protein 32
chr1_+_44115814 9.43 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr3_-_112127981 9.42 ENST00000486726.2
RP11-231E6.1
chr12_-_91546926 9.40 ENST00000550758.1
decorin
chr7_-_137028534 9.13 ENST00000348225.2
pleiotrophin
chr12_+_53773944 9.07 ENST00000551969.1
ENST00000327443.4
Sp1 transcription factor
chr11_-_129062093 9.05 ENST00000310343.9
Rho GTPase activating protein 32
chr10_-_50970322 9.02 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr12_-_114841703 9.01 ENST00000526441.1
T-box 5
chr14_+_29236269 8.87 ENST00000313071.4
forkhead box G1
chr1_+_28261533 8.84 ENST00000411604.1
ENST00000373888.4
sphingomyelin phosphodiesterase, acid-like 3B
chr3_+_156544057 8.65 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
leucine, glutamate and lysine rich 1
chr8_+_9413410 8.61 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr13_-_88323218 8.53 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr4_-_46911248 8.45 ENST00000355591.3
ENST00000505102.1
cytochrome c oxidase subunit VIIb2
chr19_+_4007644 8.42 ENST00000262971.2
protein inhibitor of activated STAT, 4
chr4_-_46911223 8.39 ENST00000396533.1
cytochrome c oxidase subunit VIIb2
chr16_-_31085514 8.10 ENST00000300849.4
zinc finger protein 668
chr7_-_137028498 7.88 ENST00000393083.2
pleiotrophin
chr1_+_202317815 7.81 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr8_-_87755878 7.78 ENST00000320005.5
cyclic nucleotide gated channel beta 3
chr4_-_57547870 7.54 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr12_+_7014126 7.52 ENST00000415834.1
ENST00000436789.1
leucine rich repeat containing 23
chr7_-_73038822 7.36 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLX interacting protein-like
chr20_-_18447667 7.27 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
double zinc ribbon and ankyrin repeat domains 1
chr5_-_42811986 7.17 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr5_-_42812143 7.11 ENST00000514985.1
selenoprotein P, plasma, 1
chr2_+_171034646 6.98 ENST00000409044.3
ENST00000408978.4
myosin IIIB
chr14_-_74551096 6.98 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr10_-_50970382 6.96 ENST00000419399.1
ENST00000432695.1
oxoglutarate dehydrogenase-like
chrX_+_13671225 6.76 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
transcription elongation factor A (SII) N-terminal and central domain containing
chr8_-_18744528 6.64 ENST00000523619.1
pleckstrin and Sec7 domain containing 3
chr16_-_55866997 6.63 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chrX_+_77166172 6.58 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr4_-_57547454 6.57 ENST00000556376.2
HOP homeobox
chr6_+_72926145 6.54 ENST00000425662.2
ENST00000453976.2
regulating synaptic membrane exocytosis 1
chr4_+_71587669 6.51 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr7_-_73038867 6.40 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLX interacting protein-like
chr8_+_94241867 6.40 ENST00000598428.1
Uncharacterized protein
chr15_+_58702742 6.37 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr17_-_41466555 6.34 ENST00000586231.1
long intergenic non-protein coding RNA 910
chr9_-_5304432 6.26 ENST00000416837.1
ENST00000308420.3
relaxin 2
chr13_-_28545276 6.16 ENST00000381020.7
caudal type homeobox 2
chr4_-_89205879 6.16 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr17_-_9929581 6.12 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chr19_-_51522955 6.01 ENST00000358789.3
kallikrein-related peptidase 10
chr14_-_74551172 5.99 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr3_+_152552685 5.97 ENST00000305097.3
purinergic receptor P2Y, G-protein coupled, 1
chr3_-_160823158 5.89 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_-_43045439 5.88 ENST00000253407.3
complement component 1, q subcomponent-like 1
chr6_-_49681235 5.83 ENST00000339139.4
cysteine-rich secretory protein 2
chr5_-_24645078 5.83 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chr14_-_82000140 5.76 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
sel-1 suppressor of lin-12-like (C. elegans)
chr1_-_152386732 5.69 ENST00000271835.3
cornulin
chr8_+_50824233 5.65 ENST00000522124.1
syntrophin, gamma 1
chr6_-_100912785 5.56 ENST00000369208.3
single-minded family bHLH transcription factor 1
chr6_-_167040731 5.49 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr13_-_36788718 5.45 ENST00000317764.6
ENST00000379881.3
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr19_-_58951496 5.36 ENST00000254166.3
zinc finger protein 132
chr6_-_62996066 5.34 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr6_+_72922505 5.33 ENST00000401910.3
regulating synaptic membrane exocytosis 1
chr11_+_24518723 5.24 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
leucine zipper protein 2
chr16_-_2264779 5.24 ENST00000333503.7
phosphoglycolate phosphatase
chr1_-_8877692 5.20 ENST00000400908.2
arginine-glutamic acid dipeptide (RE) repeats
chr3_-_160823040 5.20 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr6_+_72922590 5.12 ENST00000523963.1
regulating synaptic membrane exocytosis 1
chr9_-_5339873 5.11 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr6_+_39760129 5.08 ENST00000274867.4
dishevelled associated activator of morphogenesis 2
chr17_+_42264556 5.04 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
transmembrane and ubiquitin-like domain containing 2
chr5_-_160279207 5.02 ENST00000327245.5
ATPase, class V, type 10B
chr7_-_14029515 5.00 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ets variant 1
chr2_+_196313239 4.96 ENST00000413290.1
AC064834.1
chr4_+_106631966 4.93 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr6_+_28317685 4.93 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr11_-_108093329 4.93 ENST00000278612.8
nuclear protein, ataxia-telangiectasia locus
chr7_+_99425633 4.92 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
cytochrome P450, family 3, subfamily A, polypeptide 43
chr12_+_106751436 4.86 ENST00000228347.4
polymerase (RNA) III (DNA directed) polypeptide B
chr14_+_24583836 4.83 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr22_+_29138013 4.80 ENST00000216027.3
ENST00000398941.2
HscB mitochondrial iron-sulfur cluster co-chaperone
chr14_+_32798547 4.75 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr6_+_31783291 4.71 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr4_+_3388057 4.71 ENST00000538395.1
regulator of G-protein signaling 12
chr12_+_26348429 4.70 ENST00000242729.2
sarcospan
chr19_-_39421377 4.63 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
seryl-tRNA synthetase 2, mitochondrial
chr6_-_32095968 4.62 ENST00000375203.3
ENST00000375201.4
activating transcription factor 6 beta
chr14_+_74815116 4.62 ENST00000256362.4
vertebrae development associated
chr22_+_41777927 4.60 ENST00000266304.4
thyrotrophic embryonic factor
chr5_+_31193847 4.60 ENST00000514738.1
ENST00000265071.2
cadherin 6, type 2, K-cadherin (fetal kidney)
chr8_-_22089845 4.56 ENST00000454243.2
phytanoyl-CoA 2-hydroxylase interacting protein
chr8_-_86290333 4.52 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr12_-_52828147 4.48 ENST00000252245.5
keratin 75
chr2_+_166152283 4.44 ENST00000375427.2
sodium channel, voltage-gated, type II, alpha subunit
chrX_-_130423200 4.40 ENST00000361420.3
immunoglobulin superfamily, member 1
chr10_+_5005598 4.37 ENST00000442997.1
aldo-keto reductase family 1, member C1
chr1_+_196788887 4.36 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr7_+_74072288 4.36 ENST00000443166.1
general transcription factor IIi
chr12_-_16761007 4.33 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr8_-_22089533 4.29 ENST00000321613.3
phytanoyl-CoA 2-hydroxylase interacting protein
chr19_+_50016610 4.26 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_101000445 4.25 ENST00000534013.1
progesterone receptor
chr10_+_74451883 4.24 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr22_-_18923655 4.21 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
proline dehydrogenase (oxidase) 1
chr10_+_96522361 4.18 ENST00000371321.3
cytochrome P450, family 2, subfamily C, polypeptide 19
chr8_-_145159083 4.17 ENST00000398712.2
SHANK-associated RH domain interactor
chr3_+_167453493 4.13 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr19_-_19302931 4.12 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr17_-_64225508 4.11 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr3_+_155860751 4.07 ENST00000471742.1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr12_-_11548496 4.06 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr22_-_32766972 4.01 ENST00000382084.4
ENST00000382086.2
RFPL3 antisense
chr10_-_99447024 3.92 ENST00000370626.3
arginine vasopressin-induced 1
chr14_-_24584138 3.88 ENST00000558280.1
ENST00000561028.1
neural retina leucine zipper
chr7_+_49813255 3.86 ENST00000340652.4
von Willebrand factor C domain containing 2
chr10_-_49813090 3.84 ENST00000249601.4
Rho GTPase activating protein 22
chr19_-_41870026 3.84 ENST00000243578.3
B9 protein domain 2
chr17_-_1532106 3.83 ENST00000301335.5
ENST00000382147.4
solute carrier family 43 (amino acid system L transporter), member 2
chr12_+_52056548 3.77 ENST00000545061.1
ENST00000355133.3
sodium channel, voltage gated, type VIII, alpha subunit
chr2_-_208989225 3.74 ENST00000264376.4
crystallin, gamma D
chr1_+_196912902 3.69 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr17_-_73663168 3.66 ENST00000578201.1
ENST00000423245.2
RecQ protein-like 5
chr6_-_22297730 3.64 ENST00000306482.1
prolactin
chr6_-_91296602 3.64 ENST00000369325.3
ENST00000369327.3
mitogen-activated protein kinase kinase kinase 7
chr11_+_94706804 3.60 ENST00000335080.5
lysine (K)-specific demethylase 4D
chrX_-_139587225 3.58 ENST00000370536.2
SRY (sex determining region Y)-box 3
chr6_+_160542870 3.54 ENST00000324965.4
ENST00000457470.2
solute carrier family 22 (organic cation transporter), member 1
chr9_-_95166841 3.52 ENST00000262551.4
osteoglycin
chr1_+_209878182 3.52 ENST00000367027.3
hydroxysteroid (11-beta) dehydrogenase 1
chr11_+_92085262 3.47 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr19_+_34287751 3.46 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
potassium channel tetramerization domain containing 15
chr15_+_62853562 3.45 ENST00000561311.1
talin 2
chr2_+_68962014 3.45 ENST00000467265.1
Rho GTPase activating protein 25
chr10_-_71169031 3.44 ENST00000373307.1
tachykinin receptor 2
chr2_-_208031943 3.43 ENST00000421199.1
ENST00000457962.1
Kruppel-like factor 7 (ubiquitous)
chr12_+_122688090 3.43 ENST00000324189.4
ENST00000546192.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr17_-_18430160 3.42 ENST00000392176.3
family with sequence similarity 106, member A
chr9_-_116840728 3.40 ENST00000265132.3
alpha-1-microglobulin/bikunin precursor
chr17_+_40610862 3.40 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr8_-_42698433 3.38 ENST00000345117.2
ENST00000254250.3
THAP domain containing, apoptosis associated protein 1
chrX_-_71458802 3.37 ENST00000373657.1
ENST00000334463.3
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr8_+_119294456 3.36 ENST00000366457.2
Uncharacterized protein
chr4_-_74486347 3.34 ENST00000342081.3
Ras association (RalGDS/AF-6) domain family member 6
chr7_+_100183927 3.34 ENST00000241071.6
ENST00000360609.2
F-box protein 24
chr19_+_18942761 3.30 ENST00000599848.1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr19_-_48018203 3.29 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr22_-_32767017 3.28 ENST00000400234.1
RFPL3 antisense
chr2_+_10183651 3.27 ENST00000305883.1
Kruppel-like factor 11
chr4_-_87028478 3.27 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr5_-_20575959 3.25 ENST00000507958.1
cadherin 18, type 2
chr17_-_73663245 3.25 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RecQ protein-like 5
chr4_+_88754113 3.25 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr14_+_32798462 3.24 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr3_-_123339343 3.21 ENST00000578202.1
myosin light chain kinase
chr7_-_100183742 3.21 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr3_-_178984759 3.12 ENST00000349697.2
ENST00000497599.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr12_-_23737534 3.11 ENST00000396007.2
SRY (sex determining region Y)-box 5
chr9_-_95166884 3.10 ENST00000375561.5
osteoglycin
chr1_-_190446759 3.06 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr1_-_10532531 3.03 ENST00000377036.2
ENST00000377038.3
DNA fragmentation factor, 45kDa, alpha polypeptide
chr18_+_46065393 3.00 ENST00000256413.3
CBP80/20-dependent translation initiation factor
chr11_+_119076745 3.00 ENST00000264033.4
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr19_+_50016411 2.99 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr14_-_36789783 2.98 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MAP3K12 binding inhibitory protein 1
chr7_-_2883928 2.94 ENST00000275364.3
guanine nucleotide binding protein (G protein) alpha 12
chrX_-_18690210 2.94 ENST00000379984.3
retinoschisin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.0 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
3.6 21.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
3.2 13.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
3.2 9.7 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
3.0 9.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
2.9 23.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
2.9 8.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
2.9 28.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.5 25.0 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.3 6.9 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
2.3 22.6 GO:0016198 axon choice point recognition(GO:0016198)
2.2 6.6 GO:0071284 cellular response to lead ion(GO:0071284)
2.0 8.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.0 13.8 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
1.7 5.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
1.7 8.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
1.6 28.7 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.5 4.6 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
1.5 6.2 GO:0014807 regulation of somitogenesis(GO:0014807)
1.5 9.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.5 11.8 GO:0034587 piRNA metabolic process(GO:0034587)
1.5 26.3 GO:0007021 tubulin complex assembly(GO:0007021)
1.4 1.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.4 13.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.3 5.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
1.3 5.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.3 3.8 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
1.2 6.0 GO:0060406 positive regulation of penile erection(GO:0060406)
1.2 4.7 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
1.1 3.4 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
1.1 3.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.1 25.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.1 11.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.1 4.3 GO:0061743 motor learning(GO:0061743)
1.1 4.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
1.1 2.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.1 4.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
1.0 7.3 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.0 3.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
1.0 3.0 GO:0007231 osmosensory signaling pathway(GO:0007231)
1.0 3.9 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
1.0 2.9 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.9 6.6 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.9 6.4 GO:1901374 acetate ester transport(GO:1901374)
0.9 4.5 GO:0061032 visceral serous pericardium development(GO:0061032)
0.9 2.7 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.9 1.8 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.9 4.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.9 0.9 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.9 5.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.9 6.9 GO:0097039 CD40 signaling pathway(GO:0023035) protein linear polyubiquitination(GO:0097039)
0.9 12.8 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.8 0.8 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.8 17.0 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.8 2.4 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.8 4.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.8 60.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.8 3.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.8 9.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.8 3.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.7 2.2 GO:0051697 protein delipidation(GO:0051697)
0.7 2.2 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.7 0.7 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.7 5.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.7 4.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.7 3.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.7 6.6 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.7 2.6 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.7 2.0 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.7 3.3 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.6 1.9 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.6 1.9 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.6 2.6 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.6 0.6 GO:0048520 positive regulation of behavior(GO:0048520)
0.6 2.4 GO:0006710 androgen catabolic process(GO:0006710)
0.6 3.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.6 4.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.6 1.2 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.6 1.7 GO:0021798 neuroblast differentiation(GO:0014016) forebrain dorsal/ventral pattern formation(GO:0021798) regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.6 12.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 8.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.6 2.8 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.5 4.9 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.5 1.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.5 1.6 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.5 2.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.5 3.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.5 2.6 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) negative regulation of sperm motility(GO:1901318) positive regulation of serine-type peptidase activity(GO:1902573)
0.5 2.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.5 1.5 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.5 1.5 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.5 6.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.5 1.4 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.4 3.0 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.4 6.4 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.4 1.7 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.4 3.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 2.0 GO:0035063 nuclear speck organization(GO:0035063)
0.4 9.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 4.3 GO:0000050 urea cycle(GO:0000050)
0.4 4.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.4 1.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 7.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 4.1 GO:0060539 diaphragm development(GO:0060539)
0.4 1.5 GO:0003335 corneocyte development(GO:0003335)
0.4 5.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 19.2 GO:0006458 'de novo' protein folding(GO:0006458)
0.4 1.1 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.4 7.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.3 6.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.3 2.1 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 4.4 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.3 2.7 GO:0070475 rRNA base methylation(GO:0070475)
0.3 4.6 GO:0032196 transposition(GO:0032196)
0.3 1.6 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3 2.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 0.9 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 3.4 GO:0009642 response to light intensity(GO:0009642)
0.3 1.5 GO:0050955 thermoception(GO:0050955)
0.3 1.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3 3.4 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 8.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.3 2.5 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.3 2.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 1.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.3 1.3 GO:0030070 insulin processing(GO:0030070)
0.3 1.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 2.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.3 1.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.3 0.8 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 2.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 3.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 0.2 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.2 6.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 1.8 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.2 2.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.9 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 1.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 1.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 5.7 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 1.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 1.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 0.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 1.4 GO:0015813 L-glutamate transport(GO:0015813)
0.2 31.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 0.6 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 12.1 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 2.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 2.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 3.6 GO:0007530 sex determination(GO:0007530)
0.2 3.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 0.5 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.2 6.9 GO:0019228 neuronal action potential(GO:0019228)
0.2 5.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 3.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 3.7 GO:0007565 female pregnancy(GO:0007565)
0.2 0.7 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 4.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 2.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 0.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 1.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.2 2.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 0.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 3.4 GO:0001935 endothelial cell proliferation(GO:0001935)
0.1 2.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 2.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 1.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 2.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.8 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 1.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 15.8 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 3.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 0.6 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.5 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.1 1.8 GO:0006706 steroid catabolic process(GO:0006706)
0.1 2.3 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.2 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 2.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 6.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.3 GO:0032641 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 2.4 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.3 GO:2001188 regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 3.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 2.8 GO:0050821 protein stabilization(GO:0050821)
0.1 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.1 2.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 1.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.7 GO:0070995 NADPH oxidation(GO:0070995)
0.1 6.8 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 4.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 16.2 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 2.9 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.1 1.6 GO:0022604 regulation of cell morphogenesis(GO:0022604)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 1.9 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 5.5 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 4.1 GO:0007422 peripheral nervous system development(GO:0007422)
0.1 2.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.7 GO:0008347 glial cell migration(GO:0008347)
0.1 2.3 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.4 GO:2001023 regulation of response to drug(GO:2001023)
0.1 7.7 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 2.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 6.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 1.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 2.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 20.5 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 1.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.8 GO:0010107 potassium ion import(GO:0010107)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 2.4 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.1 4.1 GO:0070268 cornification(GO:0070268)
0.1 1.0 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 2.9 GO:0072164 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.1 3.9 GO:0031214 biomineral tissue development(GO:0031214)
0.1 0.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 3.3 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 1.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 2.1 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 11.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 8.4 GO:0007601 visual perception(GO:0007601)
0.0 2.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 9.2 GO:0006936 muscle contraction(GO:0006936)
0.0 0.7 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:1900133 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.0 1.4 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 33.2 GO:0007417 central nervous system development(GO:0007417)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 2.2 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 3.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 1.2 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.8 GO:0046461 neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 4.8 GO:0007411 axon guidance(GO:0007411)
0.0 1.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 2.5 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.6 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 2.4 GO:0060348 bone development(GO:0060348)
0.0 1.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.5 GO:0019915 lipid storage(GO:0019915)
0.0 0.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0030728 ovulation(GO:0030728)
0.0 6.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 3.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 2.5 GO:0007548 sex differentiation(GO:0007548)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0042148 meiotic DNA recombinase assembly(GO:0000707) strand invasion(GO:0042148)
0.0 1.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0043010 camera-type eye development(GO:0043010)
0.0 1.0 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.6 GO:0042593 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 0.2 GO:0071514 genetic imprinting(GO:0071514)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 22.6 GO:0032584 growth cone membrane(GO:0032584)
3.1 25.0 GO:0014802 terminal cisterna(GO:0014802)
2.4 11.8 GO:0071546 pi-body(GO:0071546)
2.3 16.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
2.1 32.9 GO:0097512 cardiac myofibril(GO:0097512)
1.7 5.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.6 9.8 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.4 6.9 GO:0071797 LUBAC complex(GO:0071797)
1.3 8.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.1 5.7 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
1.1 4.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.1 15.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.1 4.2 GO:1990246 uniplex complex(GO:1990246)
1.0 5.2 GO:0044530 supraspliceosomal complex(GO:0044530)
1.0 16.8 GO:0045277 respiratory chain complex IV(GO:0045277)
1.0 2.9 GO:0071020 post-spliceosomal complex(GO:0071020)
0.9 3.6 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.9 23.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.8 3.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.8 7.0 GO:0016013 syntrophin complex(GO:0016013)
0.7 17.8 GO:0034451 centriolar satellite(GO:0034451)
0.7 12.8 GO:0031045 dense core granule(GO:0031045)
0.6 16.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.6 2.4 GO:1990357 terminal web(GO:1990357)
0.6 1.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.6 28.7 GO:0048786 presynaptic active zone(GO:0048786)
0.6 1.8 GO:0001940 male pronucleus(GO:0001940)
0.6 4.1 GO:1990635 proximal dendrite(GO:1990635)
0.5 6.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 8.6 GO:0000242 pericentriolar material(GO:0000242)
0.5 8.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 2.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.5 2.7 GO:1990037 Lewy body core(GO:1990037)
0.4 5.9 GO:0043083 synaptic cleft(GO:0043083)
0.4 3.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.4 1.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.4 3.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4 5.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.4 95.7 GO:0043209 myelin sheath(GO:0043209)
0.4 3.9 GO:0005614 interstitial matrix(GO:0005614)
0.3 1.4 GO:0097224 sperm connecting piece(GO:0097224)
0.3 1.4 GO:0033186 CAF-1 complex(GO:0033186)
0.3 3.0 GO:0016600 flotillin complex(GO:0016600)
0.3 7.7 GO:0071437 invadopodium(GO:0071437)
0.3 3.8 GO:0036038 MKS complex(GO:0036038)
0.3 2.4 GO:0005593 FACIT collagen trimer(GO:0005593)
0.3 2.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 2.0 GO:0097452 GAIT complex(GO:0097452)
0.3 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 1.7 GO:1990130 Iml1 complex(GO:1990130)
0.2 3.1 GO:0005869 dynactin complex(GO:0005869)
0.2 10.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 7.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 22.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 15.2 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 3.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 4.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 3.3 GO:0097342 ripoptosome(GO:0097342)
0.2 0.4 GO:0034657 GID complex(GO:0034657)
0.2 2.4 GO:0030914 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.2 6.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.2 2.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 4.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 7.6 GO:0031672 A band(GO:0031672)
0.1 1.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 4.2 GO:0030057 desmosome(GO:0030057)
0.1 2.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 5.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 5.8 GO:0016235 aggresome(GO:0016235)
0.1 31.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 0.9 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 8.1 GO:0043025 neuronal cell body(GO:0043025)
0.1 10.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.1 6.3 GO:0016459 myosin complex(GO:0016459)
0.1 5.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 4.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.2 GO:0001533 cornified envelope(GO:0001533)
0.1 10.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 3.6 GO:0031904 endosome lumen(GO:0031904)
0.1 1.5 GO:0005884 actin filament(GO:0005884)
0.1 3.0 GO:0005811 lipid particle(GO:0005811)
0.1 5.9 GO:0043204 perikaryon(GO:0043204)
0.1 2.8 GO:1990391 DNA repair complex(GO:1990391)
0.1 11.4 GO:1902495 transmembrane transporter complex(GO:1902495)
0.1 2.2 GO:0000786 nucleosome(GO:0000786)
0.1 9.0 GO:0072562 blood microparticle(GO:0072562)
0.0 2.1 GO:0005902 microvillus(GO:0005902)
0.0 2.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 9.7 GO:0045121 membrane raft(GO:0045121)
0.0 1.7 GO:0043235 receptor complex(GO:0043235)
0.0 4.9 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 4.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.7 GO:0043195 terminal bouton(GO:0043195)
0.0 1.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.3 GO:0035579 specific granule membrane(GO:0035579)
0.0 6.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0097060 synaptic membrane(GO:0097060)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 1.8 GO:0030426 growth cone(GO:0030426)
0.0 2.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 17.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
3.7 11.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
3.4 20.6 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
3.2 16.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.3 22.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
2.2 6.6 GO:0032767 copper-dependent protein binding(GO:0032767)
1.8 7.3 GO:0019770 IgG receptor activity(GO:0019770)
1.7 5.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.7 5.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
1.7 8.4 GO:0061665 SUMO ligase activity(GO:0061665)
1.6 6.4 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.5 4.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.5 6.0 GO:0031685 adenosine receptor binding(GO:0031685)
1.3 6.6 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
1.2 37.7 GO:0005212 structural constituent of eye lens(GO:0005212)
1.2 9.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.2 23.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
1.2 3.6 GO:0005148 prolactin receptor binding(GO:0005148)
1.2 3.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
1.2 6.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.2 3.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2 4.6 GO:0004803 transposase activity(GO:0004803)
1.2 3.5 GO:0005174 CD40 receptor binding(GO:0005174)
1.2 5.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.2 6.9 GO:0009378 four-way junction helicase activity(GO:0009378)
1.1 3.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.1 7.8 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
1.1 61.0 GO:0017080 sodium channel regulator activity(GO:0017080)
1.1 6.6 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
1.1 11.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.1 4.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
1.0 3.0 GO:0030366 molybdopterin synthase activity(GO:0030366)
1.0 2.9 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.9 2.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.9 2.7 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.9 24.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.8 4.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.8 3.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.7 2.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.7 3.4 GO:0004995 tachykinin receptor activity(GO:0004995)
0.7 3.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.7 2.0 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.6 1.9 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.6 1.8 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.6 1.8 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.6 16.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 4.5 GO:0004064 arylesterase activity(GO:0004064)
0.6 13.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.6 4.4 GO:0034711 inhibin binding(GO:0034711)
0.5 3.8 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.5 3.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.5 1.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 1.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.5 8.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.5 1.5 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.5 2.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5 2.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.4 4.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 2.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4 8.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 1.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 3.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.4 6.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.4 1.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.4 89.7 GO:0051015 actin filament binding(GO:0051015)
0.4 1.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 3.8 GO:0039706 co-receptor binding(GO:0039706)
0.3 4.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.3 2.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 9.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 7.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 3.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 7.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 11.5 GO:0042056 chemoattractant activity(GO:0042056)
0.3 4.9 GO:0070330 aromatase activity(GO:0070330)
0.3 2.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.3 2.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 4.6 GO:0035497 cAMP response element binding(GO:0035497)
0.2 21.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 0.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 7.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 14.0 GO:0070888 E-box binding(GO:0070888)
0.2 1.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 4.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.2 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 1.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 5.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 2.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 4.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 1.0 GO:0000146 microfilament motor activity(GO:0000146)
0.2 1.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 1.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 1.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 0.4 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.2 1.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 4.1 GO:0070402 NADPH binding(GO:0070402)
0.2 48.0 GO:0005096 GTPase activator activity(GO:0005096)
0.2 4.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 3.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 2.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 3.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 23.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.1 GO:0048185 activin binding(GO:0048185)
0.1 20.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.4 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 3.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 3.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 12.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.6 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 2.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 2.9 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 3.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 3.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 12.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 6.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.7 GO:0042301 phosphate ion binding(GO:0042301)
0.1 3.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 4.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 2.2 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1 2.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 3.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0023023 MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)
0.1 10.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.8 GO:0048018 receptor agonist activity(GO:0048018)
0.1 3.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 1.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 1.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) ErbB-3 class receptor binding(GO:0043125)
0.1 2.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 2.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.9 GO:0008168 methyltransferase activity(GO:0008168)
0.1 0.4 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 2.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 2.1 GO:0005109 frizzled binding(GO:0005109)
0.1 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.8 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 5.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 45.6 GO:0005509 calcium ion binding(GO:0005509)
0.1 2.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.5 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.4 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 5.3 GO:0005179 hormone activity(GO:0005179)
0.1 1.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 3.9 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 3.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 18.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 3.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 2.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.8 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.7 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 2.5 GO:0008083 growth factor activity(GO:0008083)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0003707 steroid hormone receptor activity(GO:0003707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.5 16.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.4 22.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 21.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 8.0 PID CONE PATHWAY Visual signal transduction: Cones
0.3 6.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 6.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 2.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 6.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 4.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 11.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 11.4 PID IFNG PATHWAY IFN-gamma pathway
0.2 6.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 7.3 PID CD40 PATHWAY CD40/CD40L signaling
0.2 8.5 NABA COLLAGENS Genes encoding collagen proteins
0.1 8.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 5.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 20.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 18.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.4 PID MYC PATHWAY C-MYC pathway
0.1 2.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 17.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.6 PID INSULIN PATHWAY Insulin Pathway
0.0 2.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 3.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 21.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.9 17.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.7 6.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.5 5.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.5 13.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.4 13.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 9.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 17.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.4 6.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 6.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.3 6.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.3 4.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 5.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 8.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 9.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 4.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 2.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.4 REACTOME OPSINS Genes involved in Opsins
0.2 3.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 4.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 6.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 5.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 3.4 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.2 1.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 3.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 11.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 4.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 1.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 3.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 3.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 5.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 4.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 3.8 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 1.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 3.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 4.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 3.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 13.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.6 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 1.2 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.1 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 5.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 2.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 6.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 3.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.5 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation