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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for EN1_ESX1_GBX1

Z-value: 0.79

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Transcription factors associated with EN1_ESX1_GBX1

Gene Symbol Gene ID Gene Info
ENSG00000163064.6 engrailed homeobox 1
ENSG00000123576.5 ESX homeobox 1
ENSG00000164900.4 gastrulation brain homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GBX1hg19_v2_chr7_-_150864635_150864785-0.194.5e-03Click!
EN1hg19_v2_chr2_-_119605253_1196052640.186.3e-03Click!

Activity profile of EN1_ESX1_GBX1 motif

Sorted Z-values of EN1_ESX1_GBX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_111794446 32.90 ENST00000527950.1
crystallin, alpha B
chrX_-_13835147 28.51 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr3_+_111718036 27.74 ENST00000455401.2
transgelin 3
chr3_+_111718173 25.42 ENST00000494932.1
transgelin 3
chr3_+_111717600 25.31 ENST00000273368.4
transgelin 3
chr3_+_111717511 24.32 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr3_+_115342349 22.62 ENST00000393780.3
growth associated protein 43
chr11_-_117747434 21.52 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr11_-_117747607 21.49 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr12_-_6233828 21.46 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr11_-_117748138 21.40 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr7_+_100136811 18.86 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr16_+_58283814 17.84 ENST00000443128.2
ENST00000219299.4
coiled-coil domain containing 113
chr12_-_16759711 17.29 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr19_-_7968427 17.14 ENST00000539278.1
Uncharacterized protein
chr5_+_66300446 15.28 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr10_-_93392811 14.56 ENST00000238994.5
protein phosphatase 1, regulatory subunit 3C
chr1_-_118472216 13.82 ENST00000369443.5
ganglioside induced differentiation associated protein 2
chr12_+_81110684 13.59 ENST00000228644.3
myogenic factor 5
chr1_+_160160283 13.48 ENST00000368079.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr2_-_224467093 12.76 ENST00000305409.2
secretogranin II
chr12_+_7014064 12.44 ENST00000443597.2
leucine rich repeat containing 23
chr13_-_67802549 12.13 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr4_-_134070250 12.06 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
chr6_+_153552455 11.92 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr1_-_151762943 11.76 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
tudor and KH domain containing
chr8_+_105235572 11.72 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr1_+_160160346 11.53 ENST00000368078.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr12_+_7013897 11.52 ENST00000007969.8
ENST00000323702.5
leucine rich repeat containing 23
chr12_+_26348246 11.34 ENST00000422622.2
sarcospan
chr14_+_104182061 10.33 ENST00000216602.6
zinc finger, FYVE domain containing 21
chr14_+_104182105 10.27 ENST00000311141.2
zinc finger, FYVE domain containing 21
chr11_+_94706973 10.04 ENST00000536741.1
lysine (K)-specific demethylase 4D
chr16_-_29910853 9.96 ENST00000308713.5
seizure related 6 homolog (mouse)-like 2
chr4_-_8873531 9.74 ENST00000400677.3
H6 family homeobox 1
chr14_-_104181771 9.71 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
X-ray repair complementing defective repair in Chinese hamster cells 3
chr11_-_128894053 9.66 ENST00000392657.3
Rho GTPase activating protein 32
chr1_+_44115814 9.43 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr3_-_112127981 9.42 ENST00000486726.2
RP11-231E6.1
chr12_-_91546926 9.40 ENST00000550758.1
decorin
chr7_-_137028534 9.13 ENST00000348225.2
pleiotrophin
chr12_+_53773944 9.07 ENST00000551969.1
ENST00000327443.4
Sp1 transcription factor
chr11_-_129062093 9.05 ENST00000310343.9
Rho GTPase activating protein 32
chr10_-_50970322 9.02 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr12_-_114841703 9.01 ENST00000526441.1
T-box 5
chr14_+_29236269 8.87 ENST00000313071.4
forkhead box G1
chr1_+_28261533 8.84 ENST00000411604.1
ENST00000373888.4
sphingomyelin phosphodiesterase, acid-like 3B
chr3_+_156544057 8.65 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
leucine, glutamate and lysine rich 1
chr8_+_9413410 8.61 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr13_-_88323218 8.53 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr4_-_46911248 8.45 ENST00000355591.3
ENST00000505102.1
cytochrome c oxidase subunit VIIb2
chr19_+_4007644 8.42 ENST00000262971.2
protein inhibitor of activated STAT, 4
chr4_-_46911223 8.39 ENST00000396533.1
cytochrome c oxidase subunit VIIb2
chr16_-_31085514 8.10 ENST00000300849.4
zinc finger protein 668
chr7_-_137028498 7.88 ENST00000393083.2
pleiotrophin
chr1_+_202317815 7.81 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr8_-_87755878 7.78 ENST00000320005.5
cyclic nucleotide gated channel beta 3
chr4_-_57547870 7.54 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr12_+_7014126 7.52 ENST00000415834.1
ENST00000436789.1
leucine rich repeat containing 23
chr7_-_73038822 7.36 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLX interacting protein-like
chr20_-_18447667 7.27 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
double zinc ribbon and ankyrin repeat domains 1
chr5_-_42811986 7.17 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr5_-_42812143 7.11 ENST00000514985.1
selenoprotein P, plasma, 1
chr2_+_171034646 6.98 ENST00000409044.3
ENST00000408978.4
myosin IIIB
chr14_-_74551096 6.98 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr10_-_50970382 6.96 ENST00000419399.1
ENST00000432695.1
oxoglutarate dehydrogenase-like
chrX_+_13671225 6.76 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
transcription elongation factor A (SII) N-terminal and central domain containing
chr8_-_18744528 6.64 ENST00000523619.1
pleckstrin and Sec7 domain containing 3
chr16_-_55866997 6.63 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chrX_+_77166172 6.58 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr4_-_57547454 6.57 ENST00000556376.2
HOP homeobox
chr6_+_72926145 6.54 ENST00000425662.2
ENST00000453976.2
regulating synaptic membrane exocytosis 1
chr4_+_71587669 6.51 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr7_-_73038867 6.40 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLX interacting protein-like
chr8_+_94241867 6.40 ENST00000598428.1
Uncharacterized protein
chr15_+_58702742 6.37 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr17_-_41466555 6.34 ENST00000586231.1
long intergenic non-protein coding RNA 910
chr9_-_5304432 6.26 ENST00000416837.1
ENST00000308420.3
relaxin 2
chr13_-_28545276 6.16 ENST00000381020.7
caudal type homeobox 2
chr4_-_89205879 6.16 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr17_-_9929581 6.12 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chr19_-_51522955 6.01 ENST00000358789.3
kallikrein-related peptidase 10
chr14_-_74551172 5.99 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr3_+_152552685 5.97 ENST00000305097.3
purinergic receptor P2Y, G-protein coupled, 1
chr3_-_160823158 5.89 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_-_43045439 5.88 ENST00000253407.3
complement component 1, q subcomponent-like 1
chr6_-_49681235 5.83 ENST00000339139.4
cysteine-rich secretory protein 2
chr5_-_24645078 5.83 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chr14_-_82000140 5.76 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
sel-1 suppressor of lin-12-like (C. elegans)
chr1_-_152386732 5.69 ENST00000271835.3
cornulin
chr8_+_50824233 5.65 ENST00000522124.1
syntrophin, gamma 1
chr6_-_100912785 5.56 ENST00000369208.3
single-minded family bHLH transcription factor 1
chr6_-_167040731 5.49 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr13_-_36788718 5.45 ENST00000317764.6
ENST00000379881.3
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr19_-_58951496 5.36 ENST00000254166.3
zinc finger protein 132
chr6_-_62996066 5.34 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr6_+_72922505 5.33 ENST00000401910.3
regulating synaptic membrane exocytosis 1
chr11_+_24518723 5.24 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
leucine zipper protein 2
chr16_-_2264779 5.24 ENST00000333503.7
phosphoglycolate phosphatase
chr1_-_8877692 5.20 ENST00000400908.2
arginine-glutamic acid dipeptide (RE) repeats
chr3_-_160823040 5.20 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr6_+_72922590 5.12 ENST00000523963.1
regulating synaptic membrane exocytosis 1
chr9_-_5339873 5.11 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr6_+_39760129 5.08 ENST00000274867.4
dishevelled associated activator of morphogenesis 2
chr17_+_42264556 5.04 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
transmembrane and ubiquitin-like domain containing 2
chr5_-_160279207 5.02 ENST00000327245.5
ATPase, class V, type 10B
chr7_-_14029515 5.00 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ets variant 1
chr2_+_196313239 4.96 ENST00000413290.1
AC064834.1
chr4_+_106631966 4.93 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr6_+_28317685 4.93 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr11_-_108093329 4.93 ENST00000278612.8
nuclear protein, ataxia-telangiectasia locus
chr7_+_99425633 4.92 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
cytochrome P450, family 3, subfamily A, polypeptide 43
chr12_+_106751436 4.86 ENST00000228347.4
polymerase (RNA) III (DNA directed) polypeptide B
chr14_+_24583836 4.83 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr22_+_29138013 4.80 ENST00000216027.3
ENST00000398941.2
HscB mitochondrial iron-sulfur cluster co-chaperone
chr14_+_32798547 4.75 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr6_+_31783291 4.71 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr4_+_3388057 4.71 ENST00000538395.1
regulator of G-protein signaling 12
chr12_+_26348429 4.70 ENST00000242729.2
sarcospan
chr19_-_39421377 4.63 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
seryl-tRNA synthetase 2, mitochondrial
chr6_-_32095968 4.62 ENST00000375203.3
ENST00000375201.4
activating transcription factor 6 beta
chr14_+_74815116 4.62 ENST00000256362.4
vertebrae development associated
chr22_+_41777927 4.60 ENST00000266304.4
thyrotrophic embryonic factor
chr5_+_31193847 4.60 ENST00000514738.1
ENST00000265071.2
cadherin 6, type 2, K-cadherin (fetal kidney)
chr8_-_22089845 4.56 ENST00000454243.2
phytanoyl-CoA 2-hydroxylase interacting protein
chr8_-_86290333 4.52 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr12_-_52828147 4.48 ENST00000252245.5
keratin 75
chr2_+_166152283 4.44 ENST00000375427.2
sodium channel, voltage-gated, type II, alpha subunit
chrX_-_130423200 4.40 ENST00000361420.3
immunoglobulin superfamily, member 1
chr10_+_5005598 4.37 ENST00000442997.1
aldo-keto reductase family 1, member C1
chr1_+_196788887 4.36 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr7_+_74072288 4.36 ENST00000443166.1
general transcription factor IIi
chr12_-_16761007 4.33 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr8_-_22089533 4.29 ENST00000321613.3
phytanoyl-CoA 2-hydroxylase interacting protein
chr19_+_50016610 4.26 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_101000445 4.25 ENST00000534013.1
progesterone receptor
chr10_+_74451883 4.24 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr22_-_18923655 4.21 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
proline dehydrogenase (oxidase) 1
chr10_+_96522361 4.18 ENST00000371321.3
cytochrome P450, family 2, subfamily C, polypeptide 19
chr8_-_145159083 4.17 ENST00000398712.2
SHANK-associated RH domain interactor
chr3_+_167453493 4.13 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr19_-_19302931 4.12 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr17_-_64225508 4.11 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr3_+_155860751 4.07 ENST00000471742.1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr12_-_11548496 4.06 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr22_-_32766972 4.01 ENST00000382084.4
ENST00000382086.2
RFPL3 antisense
chr10_-_99447024 3.92 ENST00000370626.3
arginine vasopressin-induced 1
chr14_-_24584138 3.88 ENST00000558280.1
ENST00000561028.1
neural retina leucine zipper
chr7_+_49813255 3.86 ENST00000340652.4
von Willebrand factor C domain containing 2
chr10_-_49813090 3.84 ENST00000249601.4
Rho GTPase activating protein 22
chr19_-_41870026 3.84 ENST00000243578.3
B9 protein domain 2
chr17_-_1532106 3.83 ENST00000301335.5
ENST00000382147.4
solute carrier family 43 (amino acid system L transporter), member 2
chr12_+_52056548 3.77 ENST00000545061.1
ENST00000355133.3
sodium channel, voltage gated, type VIII, alpha subunit
chr2_-_208989225 3.74 ENST00000264376.4
crystallin, gamma D
chr1_+_196912902 3.69 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr17_-_73663168 3.66 ENST00000578201.1
ENST00000423245.2
RecQ protein-like 5
chr6_-_22297730 3.64 ENST00000306482.1
prolactin
chr6_-_91296602 3.64 ENST00000369325.3
ENST00000369327.3
mitogen-activated protein kinase kinase kinase 7
chr11_+_94706804 3.60 ENST00000335080.5
lysine (K)-specific demethylase 4D
chrX_-_139587225 3.58 ENST00000370536.2
SRY (sex determining region Y)-box 3
chr6_+_160542870 3.54 ENST00000324965.4
ENST00000457470.2
solute carrier family 22 (organic cation transporter), member 1
chr9_-_95166841 3.52 ENST00000262551.4
osteoglycin
chr1_+_209878182 3.52 ENST00000367027.3
hydroxysteroid (11-beta) dehydrogenase 1
chr11_+_92085262 3.47 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr19_+_34287751 3.46 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
potassium channel tetramerization domain containing 15
chr15_+_62853562 3.45 ENST00000561311.1
talin 2
chr2_+_68962014 3.45 ENST00000467265.1
Rho GTPase activating protein 25
chr10_-_71169031 3.44 ENST00000373307.1
tachykinin receptor 2
chr2_-_208031943 3.43 ENST00000421199.1
ENST00000457962.1
Kruppel-like factor 7 (ubiquitous)
chr12_+_122688090 3.43 ENST00000324189.4
ENST00000546192.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr17_-_18430160 3.42 ENST00000392176.3
family with sequence similarity 106, member A
chr9_-_116840728 3.40 ENST00000265132.3
alpha-1-microglobulin/bikunin precursor
chr17_+_40610862 3.40 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr8_-_42698433 3.38 ENST00000345117.2
ENST00000254250.3
THAP domain containing, apoptosis associated protein 1
chrX_-_71458802 3.37 ENST00000373657.1
ENST00000334463.3
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr8_+_119294456 3.36 ENST00000366457.2
Uncharacterized protein
chr4_-_74486347 3.34 ENST00000342081.3
Ras association (RalGDS/AF-6) domain family member 6
chr7_+_100183927 3.34 ENST00000241071.6
ENST00000360609.2
F-box protein 24
chr19_+_18942761 3.30 ENST00000599848.1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr19_-_48018203 3.29 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr22_-_32767017 3.28 ENST00000400234.1
RFPL3 antisense
chr2_+_10183651 3.27 ENST00000305883.1
Kruppel-like factor 11
chr4_-_87028478 3.27 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr5_-_20575959 3.25 ENST00000507958.1
cadherin 18, type 2
chr17_-_73663245 3.25 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RecQ protein-like 5
chr4_+_88754113 3.25 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr14_+_32798462 3.24 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr3_-_123339343 3.21 ENST00000578202.1
myosin light chain kinase
chr7_-_100183742 3.21 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr3_-_178984759 3.12 ENST00000349697.2
ENST00000497599.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr12_-_23737534 3.11 ENST00000396007.2
SRY (sex determining region Y)-box 5
chr9_-_95166884 3.10 ENST00000375561.5
osteoglycin
chr1_-_190446759 3.06 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr1_-_10532531 3.03 ENST00000377036.2
ENST00000377038.3
DNA fragmentation factor, 45kDa, alpha polypeptide
chr18_+_46065393 3.00 ENST00000256413.3
CBP80/20-dependent translation initiation factor
chr11_+_119076745 3.00 ENST00000264033.4
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr19_+_50016411 2.99 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr14_-_36789783 2.98 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MAP3K12 binding inhibitory protein 1
chr7_-_2883928 2.94 ENST00000275364.3
guanine nucleotide binding protein (G protein) alpha 12
chrX_-_18690210 2.94 ENST00000379984.3
retinoschisin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.0 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
3.6 21.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
3.2 13.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
3.2 9.7 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
3.0 9.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
2.9 23.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
2.9 8.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
2.9 28.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.5 25.0 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.3 6.9 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
2.3 22.6 GO:0016198 axon choice point recognition(GO:0016198)
2.2 6.6 GO:0071284 cellular response to lead ion(GO:0071284)
2.0 8.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.0 13.8 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
1.7 5.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
1.7 8.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
1.6 28.7 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.5 4.6 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
1.5 6.2 GO:0014807 regulation of somitogenesis(GO:0014807)
1.5 9.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.5 11.8 GO:0034587 piRNA metabolic process(GO:0034587)
1.5 26.3 GO:0007021 tubulin complex assembly(GO:0007021)
1.4 1.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.4 13.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.3 5.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
1.3 5.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.3 3.8 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
1.2 6.0 GO:0060406 positive regulation of penile erection(GO:0060406)
1.2 4.7 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
1.1 3.4 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
1.1 3.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.1 25.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.1 11.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.1 4.3 GO:0061743 motor learning(GO:0061743)
1.1 4.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
1.1 2.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.1 4.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
1.0 7.3 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.0 3.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
1.0 3.0 GO:0007231 osmosensory signaling pathway(GO:0007231)
1.0 3.9 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
1.0 2.9 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.9 6.6 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.9 6.4 GO:1901374 acetate ester transport(GO:1901374)
0.9 4.5 GO:0061032 visceral serous pericardium development(GO:0061032)
0.9 2.7 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.9 1.8 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.9 4.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.9 0.9 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.9 5.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.9 6.9 GO:0097039 CD40 signaling pathway(GO:0023035) protein linear polyubiquitination(GO:0097039)
0.9 12.8 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.8 0.8 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.8 17.0 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.8 2.4 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.8 4.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.8 60.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.8 3.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.8 9.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.8 3.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.7 2.2 GO:0051697 protein delipidation(GO:0051697)
0.7 2.2 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.7 0.7 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.7 5.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.7 4.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.7 3.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.7 6.6 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.7 2.6 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.7 2.0 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.7 3.3 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.6 1.9 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.6 1.9 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.6 2.6 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.6 0.6 GO:0048520 positive regulation of behavior(GO:0048520)
0.6 2.4 GO:0006710 androgen catabolic process(GO:0006710)
0.6 3.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.6 4.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.6 1.2 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.6 1.7 GO:0021798 neuroblast differentiation(GO:0014016) forebrain dorsal/ventral pattern formation(GO:0021798) regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.6 12.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 8.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.6 2.8 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.5 4.9 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.5 1.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.5 1.6 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.5 2.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.5 3.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.5 2.6 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) negative regulation of sperm motility(GO:1901318) positive regulation of serine-type peptidase activity(GO:1902573)
0.5 2.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.5 1.5 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.5 1.5 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.5 6.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.5 1.4 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.4 3.0 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.4 6.4 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.4 1.7 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.4 3.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 2.0 GO:0035063 nuclear speck organization(GO:0035063)
0.4 9.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 4.3 GO:0000050 urea cycle(GO:0000050)
0.4 4.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.4 1.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 7.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 4.1 GO:0060539 diaphragm development(GO:0060539)
0.4 1.5 GO:0003335 corneocyte development(GO:0003335)
0.4 5.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 19.2 GO:0006458 'de novo' protein folding(GO:0006458)
0.4 1.1 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.4 7.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.3 6.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.3 2.1 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 4.4 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.3 2.7 GO:0070475 rRNA base methylation(GO:0070475)
0.3 4.6 GO:0032196 transposition(GO:0032196)
0.3 1.6 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3 2.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 0.9 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 3.4 GO:0009642 response to light intensity(GO:0009642)
0.3 1.5 GO:0050955 thermoception(GO:0050955)
0.3 1.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3 3.4 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 8.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.3 2.5 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.3 2.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 1.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.3 1.3 GO:0030070 insulin processing(GO:0030070)
0.3 1.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 2.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.3 1.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.3 0.8 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 2.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 3.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 0.2 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.2 6.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 1.8 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.2 2.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.9 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 1.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 1.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 5.7 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 1.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 1.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 0.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 1.4 GO:0015813 L-glutamate transport(GO:0015813)
0.2 31.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 0.6 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 12.1 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 2.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 2.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 3.6 GO:0007530 sex determination(GO:0007530)
0.2 3.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 0.5 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.2 6.9 GO:0019228 neuronal action potential(GO:0019228)
0.2 5.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 3.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 3.7 GO:0007565 female pregnancy(GO:0007565)
0.2 0.7 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 4.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 2.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 0.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 1.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.2 2.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 0.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 3.4 GO:0001935 endothelial cell proliferation(GO:0001935)
0.1 2.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 2.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 1.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 2.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.8 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 1.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 15.8 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 3.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 0.6 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.5 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.1 1.8 GO:0006706 steroid catabolic process(GO:0006706)
0.1 2.3 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.2 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 2.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 6.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.3 GO:0032641 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 2.4 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.3 GO:2001188 regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 3.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 2.8 GO:0050821 protein stabilization(GO:0050821)
0.1 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.1 2.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 1.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.7 GO:0070995 NADPH oxidation(GO:0070995)
0.1 6.8 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 4.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 16.2 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 2.9 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.1 1.6 GO:0022604 regulation of cell morphogenesis(GO:0022604)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 1.9 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 5.5 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 4.1 GO:0007422 peripheral nervous system development(GO:0007422)
0.1 2.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.7 GO:0008347 glial cell migration(GO:0008347)
0.1 2.3 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.4 GO:2001023 regulation of response to drug(GO:2001023)
0.1 7.7 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 2.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 6.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 1.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 2.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 20.5 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 1.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.8 GO:0010107 potassium ion import(GO:0010107)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 2.4 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.1 4.1 GO:0070268 cornification(GO:0070268)
0.1 1.0 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 2.9 GO:0072164 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.1 3.9 GO:0031214 biomineral tissue development(GO:0031214)
0.1 0.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 3.3 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 1.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 2.1 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 11.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 8.4 GO:0007601 visual perception(GO:0007601)
0.0 2.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 9.2 GO:0006936 muscle contraction(GO:0006936)
0.0 0.7 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:1900133 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.0 1.4 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 33.2 GO:0007417 central nervous system development(GO:0007417)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 2.2 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 3.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 1.2 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.8 GO:0046461 neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 4.8 GO:0007411 axon guidance(GO:0007411)
0.0 1.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 2.5 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.6 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 2.4 GO:0060348 bone development(GO:0060348)
0.0 1.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.5 GO:0019915 lipid storage(GO:0019915)
0.0 0.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0030728 ovulation(GO:0030728)
0.0 6.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 3.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 2.5 GO:0007548 sex differentiation(GO:0007548)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0042148 meiotic DNA recombinase assembly(GO:0000707) strand invasion(GO:0042148)
0.0 1.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0043010 camera-type eye development(GO:0043010)
0.0 1.0 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.6 GO:0042593 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 0.2 GO:0071514 genetic imprinting(GO:0071514)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 22.6 GO:0032584 growth cone membrane(GO:0032584)
3.1 25.0 GO:0014802 terminal cisterna(GO:0014802)
2.4 11.8 GO:0071546 pi-body(GO:0071546)
2.3 16.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
2.1 32.9 GO:0097512 cardiac myofibril(GO:0097512)
1.7 5.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.6 9.8 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.4 6.9 GO:0071797 LUBAC complex(GO:0071797)
1.3 8.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.1 5.7 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
1.1 4.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.1 15.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.1 4.2 GO:1990246 uniplex complex(GO:1990246)
1.0 5.2 GO:0044530 supraspliceosomal complex(GO:0044530)
1.0 16.8 GO:0045277 respiratory chain complex IV(GO:0045277)
1.0 2.9 GO:0071020 post-spliceosomal complex(GO:0071020)
0.9 3.6 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.9 23.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.8 3.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.8 7.0 GO:0016013 syntrophin complex(GO:0016013)
0.7 17.8 GO:0034451 centriolar satellite(GO:0034451)
0.7 12.8 GO:0031045 dense core granule(GO:0031045)
0.6 16.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.6 2.4 GO:1990357 terminal web(GO:1990357)
0.6 1.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.6 28.7 GO:0048786 presynaptic active zone(GO:0048786)
0.6 1.8 GO:0001940 male pronucleus(GO:0001940)
0.6 4.1 GO:1990635 proximal dendrite(GO:1990635)
0.5 6.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 8.6 GO:0000242 pericentriolar material(GO:0000242)
0.5 8.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 2.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.5 2.7 GO:1990037 Lewy body core(GO:1990037)
0.4 5.9 GO:0043083 synaptic cleft(GO:0043083)
0.4 3.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.4 1.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.4 3.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4 5.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.4 95.7 GO:0043209 myelin sheath(GO:0043209)
0.4 3.9 GO:0005614 interstitial matrix(GO:0005614)
0.3 1.4 GO:0097224 sperm connecting piece(GO:0097224)
0.3 1.4 GO:0033186 CAF-1 complex(GO:0033186)
0.3 3.0 GO:0016600 flotillin complex(GO:0016600)
0.3 7.7 GO:0071437 invadopodium(GO:0071437)
0.3 3.8 GO:0036038 MKS complex(GO:0036038)
0.3 2.4 GO:0005593 FACIT collagen trimer(GO:0005593)
0.3 2.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 2.0 GO:0097452 GAIT complex(GO:0097452)
0.3 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 1.7 GO:1990130 Iml1 complex(GO:1990130)
0.2 3.1 GO:0005869 dynactin complex(GO:0005869)
0.2 10.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 7.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 22.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 15.2 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 3.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 4.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 3.3 GO:0097342 ripoptosome(GO:0097342)
0.2 0.4 GO:0034657 GID complex(GO:0034657)
0.2 2.4 GO:0030914 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.2 6.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.2 2.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 4.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 7.6 GO:0031672 A band(GO:0031672)
0.1 1.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 4.2 GO:0030057 desmosome(GO:0030057)
0.1 2.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 5.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 5.8 GO:0016235 aggresome(GO:0016235)
0.1 31.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 0.9 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 8.1 GO:0043025 neuronal cell body(GO:0043025)
0.1 10.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.1 6.3 GO:0016459 myosin complex(GO:0016459)
0.1 5.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 4.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.2 GO:0001533 cornified envelope(GO:0001533)
0.1 10.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 3.6 GO:0031904 endosome lumen(GO:0031904)
0.1 1.5 GO:0005884 actin filament(GO:0005884)
0.1 3.0 GO:0005811 lipid particle(GO:0005811)
0.1 5.9 GO:0043204 perikaryon(GO:0043204)
0.1 2.8 GO:1990391 DNA repair complex(GO:1990391)
0.1 11.4 GO:1902495 transmembrane transporter complex(GO:1902495)
0.1 2.2 GO:0000786 nucleosome(GO:0000786)
0.1 9.0 GO:0072562 blood microparticle(GO:0072562)
0.0 2.1 GO:0005902 microvillus(GO:0005902)
0.0 2.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 9.7 GO:0045121 membrane raft(GO:0045121)
0.0 1.7 GO:0043235 receptor complex(GO:0043235)
0.0 4.9 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 4.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.7 GO:0043195 terminal bouton(GO:0043195)
0.0 1.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.3 GO:0035579 specific granule membrane(GO:0035579)
0.0 6.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0097060 synaptic membrane(GO:0097060)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 1.8 GO:0030426 growth cone(GO:0030426)
0.0 2.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 17.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
3.7 11.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
3.4 20.6 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
3.2 16.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.3 22.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
2.2 6.6 GO:0032767 copper-dependent protein binding(GO:0032767)
1.8 7.3 GO:0019770 IgG receptor activity(GO:0019770)
1.7 5.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.7 5.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
1.7 8.4 GO:0061665 SUMO ligase activity(GO:0061665)
1.6 6.4 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.5 4.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.5 6.0 GO:0031685 adenosine receptor binding(GO:0031685)
1.3 6.6 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
1.2 37.7 GO:0005212 structural constituent of eye lens(GO:0005212)
1.2 9.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.2 23.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
1.2 3.6 GO:0005148 prolactin receptor binding(GO:0005148)
1.2 3.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
1.2 6.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.2 3.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2 4.6 GO:0004803 transposase activity(GO:0004803)
1.2 3.5 GO:0005174 CD40 receptor binding(GO:0005174)
1.2 5.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.2 6.9 GO:0009378 four-way junction helicase activity(GO:0009378)
1.1 3.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.1 7.8 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
1.1 61.0 GO:0017080 sodium channel regulator activity(GO:0017080)
1.1 6.6 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
1.1 11.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.1 4.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
1.0 3.0 GO:0030366 molybdopterin synthase activity(GO:0030366)
1.0 2.9 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.9 2.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.9 2.7 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.9 24.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.8 4.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.8 3.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.7 2.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.7 3.4 GO:0004995 tachykinin receptor activity(GO:0004995)
0.7 3.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.7 2.0 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.6 1.9 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.6 1.8 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.6 1.8 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.6 16.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 4.5 GO:0004064 arylesterase activity(GO:0004064)
0.6 13.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.6 4.4 GO:0034711 inhibin binding(GO:0034711)
0.5 3.8 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.5 3.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.5 1.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 1.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.5 8.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.5 1.5 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.5 2.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5 2.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.4 4.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 2.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4 8.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 1.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 3.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.4 6.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.4 1.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.4 89.7 GO:0051015 actin filament binding(GO:0051015)
0.4 1.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 3.8 GO:0039706 co-receptor binding(GO:0039706)
0.3 4.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.3 2.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 9.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 7.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 3.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 7.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 11.5 GO:0042056 chemoattractant activity(GO:0042056)
0.3 4.9 GO:0070330 aromatase activity(GO:0070330)
0.3 2.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.3 2.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 4.6 GO:0035497 cAMP response element binding(GO:0035497)
0.2 21.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 0.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 7.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 14.0 GO:0070888 E-box binding(GO:0070888)
0.2 1.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 4.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.2 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 1.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 5.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 2.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 4.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 1.0 GO:0000146 microfilament motor activity(GO:0000146)
0.2 1.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 1.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 1.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 0.4 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.2 1.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 4.1 GO:0070402 NADPH binding(GO:0070402)
0.2 48.0 GO:0005096 GTPase activator activity(GO:0005096)
0.2 4.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 3.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 2.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 3.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 23.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.1 GO:0048185 activin binding(GO:0048185)
0.1 20.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.4 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 3.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 3.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 12.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.6 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 2.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 2.9 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 3.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 3.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 12.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 6.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.7 GO:0042301 phosphate ion binding(GO:0042301)
0.1 3.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 4.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 2.2 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1 2.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 3.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.7