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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for EP300

Z-value: 0.04

Motif logo

Transcription factors associated with EP300

Gene Symbol Gene ID Gene Info
ENSG00000100393.9 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EP300hg19_v2_chr22_+_41487711_41487798-0.389.1e-09Click!

Activity profile of EP300 motif

Sorted Z-values of EP300 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_6308881 18.70 ENST00000382518.1
ENST00000536586.1
CD9 molecule
chrX_-_140271249 17.14 ENST00000370526.2
leucine zipper, down-regulated in cancer 1
chr8_+_30300119 17.03 ENST00000520191.1
RNA binding protein with multiple splicing
chr14_-_69445968 16.35 ENST00000438964.2
actinin, alpha 1
chr1_+_10003486 16.21 ENST00000403197.1
ENST00000377205.1
nicotinamide nucleotide adenylyltransferase 1
chr2_-_110371720 15.11 ENST00000356688.4
septin 10
chr12_+_6309517 14.77 ENST00000382519.4
ENST00000009180.4
CD9 molecule
chr14_-_69445793 14.56 ENST00000538545.2
ENST00000394419.4
actinin, alpha 1
chr14_-_69446034 14.48 ENST00000193403.6
actinin, alpha 1
chr11_-_46722117 13.37 ENST00000311956.4
Rho GTPase activating protein 1
chr16_+_66400533 12.75 ENST00000341529.3
cadherin 5, type 2 (vascular endothelium)
chr14_+_105939276 12.66 ENST00000483017.3
cysteine-rich protein 2
chr2_-_110371777 12.19 ENST00000397712.2
septin 10
chrX_+_134166333 11.63 ENST00000257013.7
family with sequence similarity 127, member A
chr2_+_46524537 11.58 ENST00000263734.3
endothelial PAS domain protein 1
chr2_+_36582857 11.14 ENST00000280527.2
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr2_+_201171242 11.06 ENST00000360760.5
spermatogenesis associated, serine-rich 2-like
chr10_-_126849588 10.67 ENST00000411419.2
C-terminal binding protein 2
chr2_+_201171372 10.12 ENST00000409140.3
spermatogenesis associated, serine-rich 2-like
chr2_-_110371412 9.99 ENST00000415095.1
ENST00000334001.6
ENST00000437928.1
ENST00000493445.1
ENST00000397714.2
ENST00000461295.1
septin 10
chr3_-_149093499 9.97 ENST00000472441.1
transmembrane 4 L six family member 1
chrX_+_23685653 9.64 ENST00000379331.3
peroxiredoxin 4
chr17_+_72427477 9.34 ENST00000342648.5
ENST00000481232.1
G protein-coupled receptor, family C, group 5, member C
chr2_+_201171064 9.22 ENST00000451764.2
spermatogenesis associated, serine-rich 2-like
chrX_+_23685563 9.11 ENST00000379341.4
peroxiredoxin 4
chr8_-_134309335 8.87 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
N-myc downstream regulated 1
chr1_-_95007193 8.28 ENST00000370207.4
ENST00000334047.7
coagulation factor III (thromboplastin, tissue factor)
chr13_-_40177261 8.25 ENST00000379589.3
lipoma HMGIC fusion partner
chr7_+_128470431 8.15 ENST00000325888.8
ENST00000346177.6
filamin C, gamma
chr19_+_16187085 8.07 ENST00000300933.4
tropomyosin 4
chr21_-_46293644 8.02 ENST00000330938.3
pituitary tumor-transforming 1 interacting protein
chr8_-_134309823 7.99 ENST00000414097.2
N-myc downstream regulated 1
chr14_+_23340822 7.92 ENST00000359591.4
low density lipoprotein receptor-related protein 10
chr16_+_69373323 7.71 ENST00000254940.5
NIP7, nucleolar pre-rRNA processing protein
chr5_-_39425290 7.67 ENST00000545653.1
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_+_110371905 7.67 ENST00000356454.3
sosondowah ankyrin repeat domain family member C
chr5_-_39425222 7.59 ENST00000320816.6
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr21_-_46293586 7.55 ENST00000445724.2
ENST00000397887.3
pituitary tumor-transforming 1 interacting protein
chr3_+_171758344 7.52 ENST00000336824.4
ENST00000423424.1
fibronectin type III domain containing 3B
chr8_+_15397732 7.51 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
tumor suppressor candidate 3
chrX_+_135229600 7.03 ENST00000370690.3
four and a half LIM domains 1
chr17_+_72426891 7.02 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr10_-_81205373 6.87 ENST00000372336.3
zinc finger, CCHC domain containing 24
chr6_+_3000057 6.81 ENST00000397717.2
NAD(P)H dehydrogenase, quinone 2
chr2_-_99224915 6.76 ENST00000328709.3
ENST00000409997.1
cytochrome c oxidase assembly factor 5
chr4_-_186456766 6.75 ENST00000284771.6
PDZ and LIM domain 3
chr4_-_186456652 6.65 ENST00000284767.5
ENST00000284770.5
PDZ and LIM domain 3
chr17_+_37844331 6.53 ENST00000578199.1
ENST00000406381.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr1_-_22263790 6.42 ENST00000374695.3
heparan sulfate proteoglycan 2
chr9_+_19049372 6.38 ENST00000380527.1
Ras-related GTP binding A
chr11_+_46402583 6.34 ENST00000359803.3
midkine (neurite growth-promoting factor 2)
chr6_+_2988847 6.28 ENST00000380472.3
ENST00000605901.1
ENST00000454015.1
NAD(P)H dehydrogenase, quinone 2
long intergenic non-protein coding RNA 1011
chr3_+_105086056 6.08 ENST00000472644.2
activated leukocyte cell adhesion molecule
chr11_+_46403194 6.03 ENST00000395569.4
ENST00000395566.4
midkine (neurite growth-promoting factor 2)
chr15_-_73925651 6.02 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
neuroplastin
chr16_+_66968343 5.99 ENST00000417689.1
ENST00000561697.1
ENST00000317091.4
ENST00000566182.1
carboxylesterase 2
chr3_+_105085734 5.97 ENST00000306107.5
activated leukocyte cell adhesion molecule
chrX_+_135229559 5.92 ENST00000394155.2
four and a half LIM domains 1
chr18_+_9334755 5.89 ENST00000262120.5
twisted gastrulation BMP signaling modulator 1
chr11_+_46403303 5.74 ENST00000407067.1
ENST00000395565.1
midkine (neurite growth-promoting factor 2)
chr12_-_105629852 5.73 ENST00000551662.1
ENST00000553097.1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr13_-_114567034 5.56 ENST00000327773.6
ENST00000357389.3
growth arrest-specific 6
chr6_+_43738444 5.55 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
vascular endothelial growth factor A
chr8_+_144816303 5.53 ENST00000533004.1
FAM83H antisense RNA 1 (head to head)
chr2_+_25015968 5.52 ENST00000380834.2
ENST00000473706.1
centromere protein O
chr17_-_79269067 5.51 ENST00000288439.5
ENST00000374759.3
solute carrier family 38, member 10
chr2_+_25016282 5.34 ENST00000260662.1
centromere protein O
chr6_-_10415218 5.32 ENST00000466073.1
ENST00000498450.1
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr2_+_192109911 5.30 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
myosin IB
chr22_-_43042968 5.29 ENST00000407623.3
ENST00000396303.3
ENST00000438270.1
cytochrome b5 reductase 3
chr2_+_192110199 5.17 ENST00000304164.4
myosin IB
chr1_-_20812690 5.16 ENST00000375078.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr11_+_46402482 5.14 ENST00000441869.1
midkine (neurite growth-promoting factor 2)
chr1_-_94079648 5.06 ENST00000370247.3
breast cancer anti-estrogen resistance 3
chr10_-_69835099 5.04 ENST00000373700.4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr11_+_46402744 5.01 ENST00000533952.1
midkine (neurite growth-promoting factor 2)
chr8_-_103668114 4.98 ENST00000285407.6
Kruppel-like factor 10
chr11_+_46722368 4.83 ENST00000311764.2
zinc finger protein 408
chr2_-_110371664 4.83 ENST00000545389.1
ENST00000423520.1
septin 10
chr11_-_86666427 4.76 ENST00000531380.1
frizzled family receptor 4
chr10_-_95360983 4.69 ENST00000371464.3
retinol binding protein 4, plasma
chr11_+_62623621 4.64 ENST00000535296.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr3_+_71803201 4.64 ENST00000304411.2
G protein-coupled receptor 27
chr14_-_38064198 4.58 ENST00000250448.2
forkhead box A1
chr1_+_18958008 4.54 ENST00000420770.2
ENST00000400661.3
paired box 7
chr15_+_22892663 4.50 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
cytoplasmic FMR1 interacting protein 1
chr11_+_62623544 4.41 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr5_-_39425068 4.36 ENST00000515700.1
ENST00000339788.6
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr12_-_8815404 4.31 ENST00000359478.2
ENST00000396549.2
microfibrillar associated protein 5
chr1_-_157108266 4.30 ENST00000326786.4
ets variant 3
chr1_+_156030937 4.30 ENST00000361084.5
RAB25, member RAS oncogene family
chr20_+_43104508 4.29 ENST00000262605.4
ENST00000372904.3
tocopherol (alpha) transfer protein-like
chr18_-_21977748 4.23 ENST00000399441.4
ENST00000319481.3
oxysterol binding protein-like 1A
chr11_+_62623512 4.20 ENST00000377892.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_-_108742957 4.18 ENST00000565488.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr17_+_7487146 4.10 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr11_-_64527425 3.97 ENST00000377432.3
phosphorylase, glycogen, muscle
chr2_-_85895295 3.94 ENST00000428225.1
ENST00000519937.2
surfactant protein B
chrX_-_153599578 3.93 ENST00000360319.4
ENST00000344736.4
filamin A, alpha
chr19_-_1174226 3.91 ENST00000587024.1
ENST00000361757.3
strawberry notch homolog 2 (Drosophila)
chr17_+_39969183 3.90 ENST00000321562.4
FK506 binding protein 10, 65 kDa
chr7_+_150756657 3.90 ENST00000413384.2
solute carrier family 4 (anion exchanger), member 2
chr5_-_137090028 3.89 ENST00000314940.4
heterogeneous nuclear ribonucleoprotein A0
chr1_+_236558694 3.88 ENST00000359362.5
EDAR-associated death domain
chr1_-_11865982 3.88 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chrX_-_17879356 3.88 ENST00000331511.1
ENST00000415486.3
ENST00000545871.1
ENST00000451717.1
retinoic acid induced 2
chr3_-_79816965 3.87 ENST00000464233.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_-_43833628 3.77 ENST00000413844.2
ENST00000372458.3
ELOVL fatty acid elongase 1
chr1_-_11866034 3.74 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_-_8939265 3.74 ENST00000489867.1
enolase 1, (alpha)
chr20_-_30311703 3.73 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2-like 1
chr17_-_71308119 3.72 ENST00000439510.2
ENST00000581014.1
ENST00000579611.1
CDC42 effector protein (Rho GTPase binding) 4
chr5_+_179125368 3.64 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
calnexin
chr19_-_1605424 3.63 ENST00000589880.1
ENST00000585671.1
ENST00000591899.3
ubiquinol-cytochrome c reductase, complex III subunit XI
chr6_-_28367510 3.61 ENST00000361028.1
zinc finger and SCAN domain containing 12
chr9_+_133454943 3.56 ENST00000319725.9
far upstream element (FUSE) binding protein 3
chr11_+_2421718 3.52 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
tumor suppressing subtransferable candidate 4
chr5_-_180237445 3.47 ENST00000393340.3
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr10_-_99161033 3.44 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr4_+_56814968 3.41 ENST00000422247.2
centrosomal protein 135kDa
chr16_-_31085514 3.33 ENST00000300849.4
zinc finger protein 668
chr8_+_17434689 3.32 ENST00000398074.3
platelet-derived growth factor receptor-like
chr3_-_185826855 3.29 ENST00000306376.5
ets variant 5
chr10_-_69834973 3.29 ENST00000395187.2
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr20_-_56286479 3.28 ENST00000265626.4
prostate transmembrane protein, androgen induced 1
chr17_-_37844267 3.27 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
post-GPI attachment to proteins 3
chr1_-_155532484 3.26 ENST00000368346.3
ENST00000548830.1
ash1 (absent, small, or homeotic)-like (Drosophila)
chr9_-_72287191 3.22 ENST00000265381.4
amyloid beta (A4) precursor protein-binding, family A, member 1
chr10_-_69835001 3.21 ENST00000513996.1
ENST00000412272.2
ENST00000395198.3
ENST00000492996.2
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr22_+_29138013 3.18 ENST00000216027.3
ENST00000398941.2
HscB mitochondrial iron-sulfur cluster co-chaperone
chr19_-_55668093 3.13 ENST00000588882.1
ENST00000586858.1
troponin I type 3 (cardiac)
chr3_-_158450475 3.11 ENST00000237696.5
retinoic acid receptor responder (tazarotene induced) 1
chr5_-_35230434 3.10 ENST00000504500.1
prolactin receptor
chr6_+_3000195 3.05 ENST00000338130.2
NAD(P)H dehydrogenase, quinone 2
chr16_+_69373661 3.05 ENST00000254941.6
NIP7, nucleolar pre-rRNA processing protein
chr6_+_3000218 3.04 ENST00000380441.1
ENST00000380455.4
ENST00000380454.4
NAD(P)H dehydrogenase, quinone 2
chr5_-_443239 3.00 ENST00000408966.2
chromosome 5 open reading frame 55
chr5_+_68530668 2.97 ENST00000506563.1
cyclin-dependent kinase 7
chr1_+_18957500 2.97 ENST00000375375.3
paired box 7
chr11_-_104035088 2.97 ENST00000302251.5
platelet derived growth factor D
chr19_+_11546153 2.97 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
protein kinase C substrate 80K-H
chr15_+_51200871 2.96 ENST00000560508.1
adaptor-related protein complex 4, epsilon 1 subunit
chr14_-_36990354 2.89 ENST00000518149.1
NK2 homeobox 1
chr6_+_126240442 2.87 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
nuclear receptor coactivator 7
chr19_-_11039261 2.86 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
Yip1 domain family, member 2
chr19_+_11546093 2.85 ENST00000591462.1
protein kinase C substrate 80K-H
chr2_-_120980939 2.82 ENST00000426077.2
transmembrane protein 185B
chr10_+_114710211 2.79 ENST00000349937.2
ENST00000369397.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr6_+_31865552 2.74 ENST00000469372.1
ENST00000497706.1
complement component 2
chr17_+_4843679 2.73 ENST00000576229.1
ring finger protein 167
chr3_+_130745688 2.72 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NIMA-related kinase 11
chr5_+_96079240 2.71 ENST00000515663.1
calpastatin
chr6_-_28226984 2.71 ENST00000423974.2
zinc finger with KRAB and SCAN domains 4
chr2_+_204193129 2.68 ENST00000417864.1
abl-interactor 2
chr8_+_106330920 2.68 ENST00000407775.2
zinc finger protein, FOG family member 2
chr17_-_7518145 2.68 ENST00000250113.7
ENST00000571597.1
fragile X mental retardation, autosomal homolog 2
chr18_+_3262415 2.67 ENST00000581193.1
ENST00000400175.5
myosin, light chain 12B, regulatory
chr8_-_99306564 2.65 ENST00000430223.2
NIPA-like domain containing 2
chr1_-_244013384 2.64 ENST00000366539.1
v-akt murine thymoma viral oncogene homolog 3
chr5_-_180236811 2.63 ENST00000446023.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr22_+_20104947 2.62 ENST00000402752.1
RAN binding protein 1
chr19_-_4670345 2.61 ENST00000599630.1
ENST00000262947.3
chromosome 19 open reading frame 10
chr20_+_44035200 2.58 ENST00000372717.1
ENST00000360981.4
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_+_131781290 2.58 ENST00000425719.2
ENST00000374784.1
neurotrimin
chr2_+_204193149 2.57 ENST00000422511.2
abl-interactor 2
chr19_-_6110474 2.57 ENST00000587181.1
ENST00000587321.1
ENST00000586806.1
ENST00000589742.1
ENST00000592546.1
ENST00000303657.5
regulatory factor X, 2 (influences HLA class II expression)
chr17_+_7482785 2.55 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68 molecule
chr8_-_99306611 2.51 ENST00000341166.3
NIPA-like domain containing 2
chr4_+_75480629 2.51 ENST00000380846.3
amphiregulin B
chr22_-_29075853 2.51 ENST00000397906.2
tetratricopeptide repeat domain 28
chr3_+_130745769 2.47 ENST00000412440.2
NIMA-related kinase 11
chr19_-_55658281 2.46 ENST00000585321.2
ENST00000587465.2
troponin T type 1 (skeletal, slow)
chr22_-_20104700 2.44 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr9_-_139094988 2.44 ENST00000371746.3
LIM homeobox 3
chr16_+_4784458 2.44 ENST00000590191.1
chromosome 16 open reading frame 71
chr15_+_74466012 2.40 ENST00000249842.3
immunoglobulin superfamily containing leucine-rich repeat
chr11_-_107582775 2.39 ENST00000305991.2
sarcolipin
chr1_-_43855444 2.39 ENST00000372455.4
mediator complex subunit 8
chr5_-_137878887 2.39 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
eukaryotic translation termination factor 1
chr1_-_43855479 2.38 ENST00000290663.6
ENST00000372457.4
mediator complex subunit 8
chr4_+_56262115 2.38 ENST00000506198.1
ENST00000381334.5
ENST00000542052.1
transmembrane protein 165
chr4_+_75311019 2.37 ENST00000502307.1
amphiregulin
chr5_+_68530697 2.36 ENST00000256443.3
ENST00000514676.1
cyclin-dependent kinase 7
chr16_-_66968265 2.36 ENST00000567511.1
ENST00000422424.2
family with sequence similarity 96, member B
chr4_-_121993673 2.34 ENST00000379692.4
neuron-derived neurotrophic factor
chr5_+_174151536 2.34 ENST00000239243.6
ENST00000507785.1
msh homeobox 2
chr6_+_26087646 2.32 ENST00000309234.6
hemochromatosis
chr3_+_19988885 2.32 ENST00000422242.1
RAB5A, member RAS oncogene family
chr12_-_123215306 2.28 ENST00000356987.2
ENST00000436083.2
hydroxycarboxylic acid receptor 1
chr6_+_26087509 2.28 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
hemochromatosis
chr10_+_114709999 2.27 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr5_+_179125907 2.27 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
calnexin
chr15_+_51200859 2.25 ENST00000261842.5
adaptor-related protein complex 4, epsilon 1 subunit
chr1_-_36235559 2.24 ENST00000251195.5
claspin
chrX_+_37208521 2.23 ENST00000378628.4
proline rich Gla (G-carboxyglutamic acid) 1
chr12_+_52463751 2.21 ENST00000336854.4
ENST00000550604.1
ENST00000553049.1
ENST00000548915.1
chromosome 12 open reading frame 44
chr1_-_161102421 2.20 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
death effector domain containing
chr19_+_11546440 2.20 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
protein kinase C substrate 80K-H
chr2_+_113816685 2.19 ENST00000393200.2
interleukin 36 receptor antagonist
chr7_-_35734730 2.19 ENST00000396081.1
ENST00000311350.3
HERPUD family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of EP300

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 19.6 GO:0035026 leading edge cell differentiation(GO:0035026)
4.7 28.3 GO:0030421 defecation(GO:0030421)
4.5 13.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
3.7 18.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
3.0 33.5 GO:0009414 response to water deprivation(GO:0009414)
2.8 45.4 GO:0051639 actin filament network formation(GO:0051639)
2.8 8.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.6 13.2 GO:0060356 leucine import(GO:0060356)
2.5 7.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
2.1 17.1 GO:0043129 surfactant homeostasis(GO:0043129)
2.1 6.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.9 5.6 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159) renal albumin absorption(GO:0097018) oligodendrocyte apoptotic process(GO:0097252) regulation of renal albumin absorption(GO:2000532)
1.8 16.2 GO:0006531 aspartate metabolic process(GO:0006531)
1.7 13.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.6 6.6 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.6 12.7 GO:0015693 magnesium ion transport(GO:0015693)
1.5 4.6 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
1.5 16.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
1.5 7.6 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
1.5 6.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
1.3 5.3 GO:0003409 optic cup structural organization(GO:0003409)
1.3 17.1 GO:0060137 maternal process involved in parturition(GO:0060137)
1.3 6.5 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.3 3.9 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
1.3 3.9 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
1.2 4.8 GO:0061304 extracellular matrix-cell signaling(GO:0035426) retinal blood vessel morphogenesis(GO:0061304)
1.2 10.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.2 2.3 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.1 4.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
1.1 4.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
1.1 3.3 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.1 18.6 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
1.0 3.0 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
1.0 5.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.9 4.7 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.9 4.6 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.9 3.7 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.9 2.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.8 5.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.8 3.3 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.8 2.4 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.7 1.4 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.7 2.0 GO:0090076 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) relaxation of skeletal muscle(GO:0090076)
0.7 4.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.7 3.9 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.7 3.9 GO:0071105 response to interleukin-11(GO:0071105)
0.6 3.8 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6 4.4 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.6 19.2 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.6 15.6 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.6 1.7 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.6 2.9 GO:0021759 globus pallidus development(GO:0021759)
0.5 3.7 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.5 3.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.5 4.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.5 4.2 GO:0015866 ADP transport(GO:0015866)
0.5 6.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.5 2.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.5 3.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.5 1.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.5 4.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.5 8.0 GO:0031268 pseudopodium organization(GO:0031268)
0.5 12.1 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.5 5.8 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.5 3.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.5 3.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.5 0.9 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.4 1.3 GO:0006550 isoleucine catabolic process(GO:0006550)
0.4 2.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 1.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.4 1.3 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.4 2.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 6.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 3.4 GO:0030578 PML body organization(GO:0030578)
0.4 3.9 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.4 5.9 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.4 1.1 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.4 2.2 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.4 9.3 GO:0006491 N-glycan processing(GO:0006491)
0.4 1.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 2.8 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.4 5.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.4 1.4 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.4 10.9 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3 3.1 GO:0015747 urate transport(GO:0015747)
0.3 1.0 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.3 1.7 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.3 1.4 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
0.3 2.4 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.3 4.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 1.0 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.3 1.5 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.3 1.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.3 0.9 GO:0070940 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052) dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 2.6 GO:0001675 acrosome assembly(GO:0001675)
0.3 4.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.3 1.7 GO:0071907 determination of pancreatic left/right asymmetry(GO:0035469) determination of digestive tract left/right asymmetry(GO:0071907)
0.3 3.3 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 0.8 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.3 2.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.3 3.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3 0.8 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 1.0 GO:0019086 late viral transcription(GO:0019086)
0.2 4.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 0.7 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2 3.3 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.2 5.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 0.7 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.2 2.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 0.5 GO:0051031 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 1.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.2 2.3 GO:0061042 vascular wound healing(GO:0061042)
0.2 1.4 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.2 1.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.6 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2 10.6 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2 1.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 2.0 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2 1.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 0.8 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.2 0.6 GO:0051182 coenzyme transport(GO:0051182)
0.2 1.6 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 2.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 1.8 GO:0071313 cellular response to caffeine(GO:0071313)
0.2 11.7 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.2 6.0 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.2 3.1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 8.0 GO:0048747 muscle fiber development(GO:0048747)
0.2 0.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 3.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 2.4 GO:0006449 regulation of translational termination(GO:0006449)
0.2 2.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 5.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 7.0 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 0.9 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 2.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.7 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.6 GO:0090069 regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232)
0.1 0.7 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 5.0 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 0.8 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.3 GO:1900138 oxidative stress-induced premature senescence(GO:0090403) negative regulation of phospholipase A2 activity(GO:1900138)
0.1 0.5 GO:0021553 olfactory nerve development(GO:0021553) axonogenesis involved in innervation(GO:0060385) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 1.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 7.7 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 5.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.1 0.2 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.1 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.1 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.7 GO:0006701 progesterone biosynthetic process(GO:0006701) Sertoli cell proliferation(GO:0060011)
0.1 0.4 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.5 GO:0099590 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) neurotransmitter receptor internalization(GO:0099590)
0.1 6.7 GO:0042255 ribosome assembly(GO:0042255)
0.1 3.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 4.3 GO:0097435 fibril organization(GO:0097435)
0.1 7.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 9.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 4.4 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 0.3 GO:2000314 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.6 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 3.2 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.1 1.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 2.6 GO:0008038 neuron recognition(GO:0008038)
0.1 3.2 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.1 3.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 3.9 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.9 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 2.1 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 0.3 GO:0060013 righting reflex(GO:0060013)
0.1 0.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.5 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269)
0.1 2.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 1.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.1 7.9 GO:0048839 inner ear development(GO:0048839)
0.1 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 1.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.9 GO:0001696 gastric acid secretion(GO:0001696)
0.0 8.5 GO:0006814 sodium ion transport(GO:0006814)
0.0 1.5 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 1.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 2.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.6 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.4 GO:2000757 negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 1.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 2.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.1 GO:0007566 embryo implantation(GO:0007566)
0.0 1.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 8.6 GO:0007507 heart development(GO:0007507)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.3 GO:0050890 cognition(GO:0050890)
0.0 2.6 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.2 GO:0015825 L-serine transport(GO:0015825)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.0 GO:0070459 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) prolactin secretion(GO:0070459)
0.0 0.3 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 45.4 GO:0005916 fascia adherens(GO:0005916)
2.2 19.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.3 5.3 GO:0070985 TFIIK complex(GO:0070985)
1.3 3.9 GO:0031523 Myb complex(GO:0031523)
1.3 5.1 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
1.2 13.4 GO:0097443 sorting endosome(GO:0097443)
1.2 7.1 GO:1990130 Iml1 complex(GO:1990130)
1.1 33.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.0 5.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.8 10.7 GO:0097470 ribbon synapse(GO:0097470)
0.8 4.6 GO:1990357 terminal web(GO:1990357)
0.7 4.1 GO:0071817 MMXD complex(GO:0071817)
0.6 7.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.6 8.3 GO:0031209 SCAR complex(GO:0031209)
0.6 25.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.6 3.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.5 17.0 GO:0005685 U1 snRNP(GO:0005685)
0.5 6.0 GO:0060077 inhibitory synapse(GO:0060077)
0.5 3.9 GO:0097208 alveolar lamellar body(GO:0097208)
0.5 2.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.4 1.8 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.4 8.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.4 2.8 GO:0032584 growth cone membrane(GO:0032584)
0.4 12.4 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.4 5.3 GO:0005833 hemoglobin complex(GO:0005833)
0.4 12.1 GO:0042101 T cell receptor complex(GO:0042101)
0.4 8.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.3 4.4 GO:0036038 MKS complex(GO:0036038)
0.3 35.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.3 3.0 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.3 3.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 1.0 GO:0035838 growing cell tip(GO:0035838)
0.3 2.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.3 1.5 GO:0032444 activin responsive factor complex(GO:0032444)
0.3 4.6 GO:0005861 troponin complex(GO:0005861)
0.2 7.6 GO:0045202 synapse(GO:0045202)
0.2 1.7 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.2 1.6 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 6.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 4.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 2.5 GO:0097433 dense body(GO:0097433)
0.2 4.3 GO:0031143 pseudopodium(GO:0031143)
0.2 1.2 GO:0043204 perikaryon(GO:0043204)
0.2 8.3 GO:0031904 endosome lumen(GO:0031904)
0.2 6.9 GO:0043034 costamere(GO:0043034)
0.1 13.7 GO:0016459 myosin complex(GO:0016459)
0.1 1.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 4.8 GO:0016592 mediator complex(GO:0016592)
0.1 0.8 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 1.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 13.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 9.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 13.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 7.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 10.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 11.3 GO:0030018 Z disc(GO:0030018)
0.1 0.6 GO:0000145 exocyst(GO:0000145)
0.1 2.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 4.5 GO:0005902 microvillus(GO:0005902)
0.1 0.3 GO:0016600 flotillin complex(GO:0016600)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.4 GO:0014704 intercalated disc(GO:0014704)
0.1 1.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 14.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 20.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 14.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.0 GO:0071564 npBAF complex(GO:0071564) nBAF complex(GO:0071565)
0.0 3.0 GO:0008021 synaptic vesicle(GO:0008021)
0.0 16.7 GO:0005856 cytoskeleton(GO:0005856)
0.0 8.2 GO:0005925 focal adhesion(GO:0005925)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 3.8 GO:0030133 transport vesicle(GO:0030133)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 2.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 2.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.2 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
4.8 19.2 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
2.4 17.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
2.3 18.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.8 45.4 GO:0017166 vinculin binding(GO:0017166)
1.5 7.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
1.5 10.7 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.5 6.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.5 6.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.3 13.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.2 6.0 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
1.1 3.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.0 4.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
1.0 3.9 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.0 5.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.9 5.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.9 19.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.9 5.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.8 7.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7 4.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 3.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.6 3.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.6 6.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.6 0.6 GO:0051185 coenzyme transporter activity(GO:0051185)
0.5 7.7 GO:0031014 troponin T binding(GO:0031014)
0.5 4.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.5 4.2 GO:0015217 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.5 3.6 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 4.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.5 10.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.4 5.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.4 13.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 2.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.4 4.6 GO:0039706 co-receptor binding(GO:0039706)
0.4 2.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.4 5.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.4 2.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 10.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 2.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.4 1.8 GO:0070568 guanylyltransferase activity(GO:0070568)
0.4 3.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 7.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.3 6.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 1.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.3 5.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.3 1.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.3 3.7 GO:0051434 BH3 domain binding(GO:0051434)
0.3 2.0 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.3 2.0 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.3 4.7 GO:0016918 retinal binding(GO:0016918)
0.3 3.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 11.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 6.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.3 11.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 1.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 4.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 1.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.3 3.3 GO:0030957 Tat protein binding(GO:0030957)
0.3 1.5 GO:0035258 steroid hormone receptor binding(GO:0035258)
0.2 3.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 5.9 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 18.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 2.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 6.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 1.6 GO:0097643 amylin receptor activity(GO:0097643)
0.2 3.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 3.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 37.2 GO:0044325 ion channel binding(GO:0044325)
0.2 1.3 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 33.6 GO:0005178 integrin binding(GO:0005178)
0.2 4.2 GO:0005537 mannose binding(GO:0005537)
0.2 1.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 3.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 2.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 1.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 2.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 7.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.2 4.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 28.9 GO:0008201 heparin binding(GO:0008201)
0.2 0.7 GO:0008940 nitrate reductase activity(GO:0008940)
0.2 4.3 GO:0031489 myosin V binding(GO:0031489)
0.2 4.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.6 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 18.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.9 GO:0045569 TRAIL binding(GO:0045569)
0.2 1.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.2 1.5 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.2 11.1 GO:0002039 p53 binding(GO:0002039)
0.2 0.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 2.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 4.2 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.7 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 3.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.6 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 3.9 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 4.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 3.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 3.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.8 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 3.1 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.1 1.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 2.0 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 7.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 2.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 1.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 3.4 GO:0046332 SMAD binding(GO:0046332)
0.1 1.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 23.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 26.7 GO:0005525 GTP binding(GO:0005525)
0.1 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 5.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 6.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 17.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.2 GO:0005272 sodium channel activity(GO:0005272)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 2.7 GO:0016788 hydrolase activity, acting on ester bonds(GO:0016788)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 3.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 73.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.5 42.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.4 8.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.4 13.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 18.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.3 25.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.3 4.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 20.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 11.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 6.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 6.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 4.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 10.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 3.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 8.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 13.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 23.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 6.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 6.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 4.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 3.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 3.1 PID CDC42 PATHWAY CDC42 signaling events
0.1 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 6.6 PID E2F PATHWAY E2F transcription factor network
0.1 5.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 4.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.9 PID ATR PATHWAY ATR signaling pathway
0.0 1.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 56.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
1.1 19.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.9 15.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.5 15.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 29.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 9.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4 17.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.3 6.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 29.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 8.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 15.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 8.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 5.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 3.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 14.9 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.2 10.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 3.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 5.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 4.8 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 3.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 2.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 3.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 8.5