GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
EPAS1 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000116016.9	endothelial PAS domain protein 1
BCL3 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000069399.8	BCL3 transcription coactivator

Gene	Promoter	Pearson corr. coef.	P-value	Plot
EPAS1	hg19_v2_chr2_+_46524537_46524553	0.55	9.6e-19	Click!
BCL3	hg19_v2_chr19_+_45251804_45251840	-0.22	8.7e-04	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_+_35629702 Show fit	124.39	ENST00000351325.4	FXYD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 1
chr15_-_60690932 Show fit	71.07	ENST00000559818.1	ANXA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	annexin A2
chr20_+_10199468 Show fit	57.06	ENST00000254976.2 ENST00000304886.2	SNAP25 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptosomal-associated protein, 25kDa
chr16_-_70719925 Show fit	54.56	ENST00000338779.6	MTSS1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	metastasis suppressor 1-like
chr3_-_58572760 Show fit	51.71	ENST00000447756.2	FAM107A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 107, member A
chr1_+_6845384 Show fit	45.50	ENST00000303635.7	CAMTA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calmodulin binding transcription activator 1
chr6_+_31620191 Show fit	44.56	ENST00000375918.2 ENST00000375920.4	APOM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein M
chr8_+_21915368 Show fit	43.97	ENST00000265800.5 ENST00000517418.1	DMTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dematin actin binding protein
chr19_+_56915668 Show fit	42.39	ENST00000333201.9 ENST00000391778.3	ZNF583 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 583
chr4_-_5894777 Show fit	37.87	ENST00000324989.7	CRMP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collapsin response mediator protein 1
chr8_-_134309335 Show fit	37.07	ENST00000522890.1 ENST00000323851.7 ENST00000518176.1 ENST00000354944.5 ENST00000537882.1 ENST00000522476.1 ENST00000518066.1 ENST00000521544.1 ENST00000518480.1 ENST00000523892.1	NDRG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	N-myc downstream regulated 1
chr2_+_20646824 Show fit	36.93	ENST00000272233.4	RHOB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member B
chr8_-_27462822 Show fit	36.61	ENST00000522098.1	CLU Links Ensembl NCBI GeneCards UniProt NextProt Show fit	clusterin
chr16_+_6069072 Show fit	36.17	ENST00000547605.1 ENST00000550418.1 ENST00000553186.1	RBFOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_+_158141806 Show fit	36.10	ENST00000393815.2	GRIA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, AMPA 2
chr2_+_203499901 Show fit	35.45	ENST00000303116.6 ENST00000392238.2	FAM117B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 117, member B
chr19_+_35630022 Show fit	35.33	ENST00000589209.1	FXYD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 1
chr7_+_154002189 Show fit	32.48	ENST00000332007.3	DPP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dipeptidyl-peptidase 6
chr16_+_22825475 Show fit	32.33	ENST00000261374.3	HS3ST2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr17_+_73750699 Show fit	30.60	ENST00000584939.1	ITGB4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, beta 4
chr11_-_134281812 Show fit	30.16	ENST00000392580.1 ENST00000312527.4	B3GAT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr22_+_41956767 Show fit	30.10	ENST00000306149.7	CSDC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cold shock domain containing C2, RNA binding
chr4_-_174320687 Show fit	30.02	ENST00000296506.3	SCRG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stimulator of chondrogenesis 1
chr19_-_37019562 Show fit	29.69	ENST00000523638.1	ZNF260 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 260
chr3_-_195310802 Show fit	29.57	ENST00000421243.1 ENST00000453131.1	APOD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein D
chr7_+_87257854 Show fit	29.29	ENST00000394654.3	RUNDC3B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RUN domain containing 3B
chr12_-_16761007 Show fit	28.85	ENST00000354662.1 ENST00000441439.2	LMO3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain only 3 (rhombotin-like 2)
chr14_-_21493649 Show fit	28.77	ENST00000553442.1 ENST00000555869.1 ENST00000556457.1 ENST00000397844.2 ENST00000554415.1	NDRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDRG family member 2
chr16_+_6069586 Show fit	28.64	ENST00000547372.1	RBFOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_21978312 Show fit	28.60	ENST00000359708.4 ENST00000290101.4	RAP1GAP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAP1 GTPase activating protein
chr3_-_52479043 Show fit	28.13	ENST00000231721.2 ENST00000475739.1	SEMA3G Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr22_+_39853258 Show fit	27.99	ENST00000341184.6	MGAT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr11_-_125366089 Show fit	27.65	ENST00000366139.3 ENST00000278919.3	FEZ1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fasciculation and elongation protein zeta 1 (zygin I)
chr19_+_45445491 Show fit	27.48	ENST00000592954.1 ENST00000419266.2 ENST00000589057.1	APOC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit APOC4-APOC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein C-IV APOC4-APOC2 readthrough (NMD candidate)
chr1_+_184356188 Show fit	27.18	ENST00000235307.6	C1orf21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 21
chr19_-_38714847 Show fit	26.85	ENST00000420980.2 ENST00000355526.4	DPF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	D4, zinc and double PHD fingers family 1
chr7_+_121513143 Show fit	26.61	ENST00000393386.2	PTPRZ1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr7_+_87257701 Show fit	26.55	ENST00000338056.3 ENST00000493037.1	RUNDC3B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RUN domain containing 3B
chr12_+_121088291 Show fit	26.36	ENST00000351200.2	CABP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium binding protein 1
chr8_+_10530155 Show fit	25.64	ENST00000521818.1	C8orf74 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 8 open reading frame 74
chr1_+_110453608 Show fit	25.41	ENST00000369801.1	CSF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	colony stimulating factor 1 (macrophage)
chr11_+_10472223 Show fit	24.79	ENST00000396554.3 ENST00000524866.1	AMPD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenosine monophosphate deaminase 3
chr17_+_1665345 Show fit	24.71	ENST00000576406.1 ENST00000571149.1	SERPINF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_+_21916710 Show fit	24.67	ENST00000523266.1 ENST00000519907.1	DMTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dematin actin binding protein
chr7_+_95401877 Show fit	24.33	ENST00000524053.1 ENST00000324972.6 ENST00000537881.1 ENST00000437599.1 ENST00000359388.4 ENST00000413338.1	DYNC1I1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, cytoplasmic 1, intermediate chain 1
chr8_+_21916680 Show fit	24.25	ENST00000358242.3 ENST00000415253.1	DMTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dematin actin binding protein
chr15_+_74422585 Show fit	24.23	ENST00000561740.1 ENST00000435464.1 ENST00000453268.2	ISLR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin superfamily containing leucine-rich repeat 2
chr19_+_30863271 Show fit	24.13	ENST00000355537.3	ZNF536 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 536
chr5_-_42825983 Show fit	24.04	ENST00000506577.1	SEPP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	selenoprotein P, plasma, 1
chr1_+_27561104 Show fit	23.94	ENST00000361771.3	WDTC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD and tetratricopeptide repeats 1
chr16_+_5008290 Show fit	23.81	ENST00000251170.7	SEC14L5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEC14-like 5 (S. cerevisiae)
chr7_+_73442422 Show fit	23.79	ENST00000358929.4 ENST00000431562.1 ENST00000320492.7 ENST00000438906.1	ELN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	elastin
chr2_+_25016282 Show fit	23.42	ENST00000260662.1	CENPO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein O
chr12_+_66218212 Show fit	23.31	ENST00000393578.3 ENST00000425208.2 ENST00000536545.1 ENST00000354636.3	HMGA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group AT-hook 2
chr4_+_158141843 Show fit	23.27	ENST00000509417.1 ENST00000296526.7	GRIA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, AMPA 2
chr17_+_17942594 Show fit	23.18	ENST00000268719.4	GID4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GID complex subunit 4
chr7_+_95401851 Show fit	23.08	ENST00000447467.2	DYNC1I1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, cytoplasmic 1, intermediate chain 1
chr3_-_58613323 Show fit	23.00	ENST00000474531.1 ENST00000465970.1	FAM107A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 107, member A
chr2_-_152955213 Show fit	22.55	ENST00000427385.1	CACNB4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium channel, voltage-dependent, beta 4 subunit
chr7_+_29519662 Show fit	22.43	ENST00000424025.2 ENST00000439711.2 ENST00000421775.2	CHN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chimerin 2
chr9_+_103790991 Show fit	22.35	ENST00000374874.3	LPPR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Lipid phosphate phosphatase-related protein type 1
chr6_+_126070726 Show fit	22.14	ENST00000368364.3	HEY2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hes-related family bHLH transcription factor with YRPW motif 2
chr2_+_25015968 Show fit	22.01	ENST00000380834.2 ENST00000473706.1	CENPO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein O
chr3_-_167813672 Show fit	22.00	ENST00000470487.1	GOLIM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	golgi integral membrane protein 4
chr3_-_127541679 Show fit	21.89	ENST00000265052.5	MGLL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	monoglyceride lipase
chrX_+_101906294 Show fit	21.89	ENST00000361600.5 ENST00000415986.1 ENST00000444152.1 ENST00000537097.1	GPRASP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor associated sorting protein 1
chr11_-_89224508 Show fit	21.75	ENST00000525196.1	NOX4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADPH oxidase 4
chr1_+_110453462 Show fit	21.73	ENST00000488198.1	CSF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	colony stimulating factor 1 (macrophage)
chr17_+_8213590 Show fit	21.43	ENST00000361926.3	ARHGEF15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho guanine nucleotide exchange factor (GEF) 15
chr12_-_12491608 Show fit	21.36	ENST00000545735.1	MANSC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MANSC domain containing 1
chr1_+_110453109 Show fit	21.32	ENST00000525659.1	CSF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	colony stimulating factor 1 (macrophage)
chr1_-_21671968 Show fit	21.18	ENST00000415912.2	ECE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	endothelin converting enzyme 1
chr1_+_27561007 Show fit	21.05	ENST00000319394.3	WDTC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD and tetratricopeptide repeats 1
chr8_-_110620284 Show fit	20.92	ENST00000529690.1	SYBU Links Ensembl NCBI GeneCards UniProt NextProt Show fit	syntabulin (syntaxin-interacting)
chr19_+_35630628 Show fit	20.82	ENST00000588715.1 ENST00000588607.1	FXYD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 1
chr20_+_57875658 Show fit	20.66	ENST00000371025.3	EDN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	endothelin 3
chr4_+_158141899 Show fit	20.49	ENST00000264426.9 ENST00000506284.1	GRIA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, AMPA 2
chr11_-_111783595 Show fit	20.47	ENST00000528628.1	CRYAB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin, alpha B
chr19_-_47975417 Show fit	20.32	ENST00000236877.6	SLC8A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 8 (sodium/calcium exchanger), member 2
chr12_+_57157100 Show fit	20.19	ENST00000322165.1	HSD17B6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid (17-beta) dehydrogenase 6
chr9_+_87283430 Show fit	20.14	ENST00000376214.1 ENST00000376213.1	NTRK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neurotrophic tyrosine kinase, receptor, type 2
chr19_-_40562063 Show fit	20.14	ENST00000598845.1 ENST00000593605.1 ENST00000221355.6 ENST00000434248.1	ZNF780B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 780B
chr19_-_16582815 Show fit	20.13	ENST00000455140.2 ENST00000248070.6 ENST00000594975.1	EPS15L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	epidermal growth factor receptor pathway substrate 15-like 1
chr22_+_19705928 Show fit	20.05	ENST00000383045.3 ENST00000438754.2	SEPT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	septin 5
chr16_+_58283814 Show fit	20.01	ENST00000443128.2 ENST00000219299.4	CCDC113 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 113
chr8_+_27348626 Show fit	19.94	ENST00000517536.1	EPHX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	epoxide hydrolase 2, cytoplasmic
chr19_+_57019212 Show fit	19.68	ENST00000308031.5 ENST00000591537.1	ZNF471 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 471
chr11_-_107582775 Show fit	19.62	ENST00000305991.2	SLN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sarcolipin
chr17_+_64961026 Show fit	19.61	ENST00000262138.3	CACNG4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium channel, voltage-dependent, gamma subunit 4
chr14_-_64970494 Show fit	19.60	ENST00000608382.1	ZBTB25 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and BTB domain containing 25
chr14_+_96505659 Show fit	19.48	ENST00000555004.1	C14orf132 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 14 open reading frame 132
chr8_+_144816303 Show fit	19.41	ENST00000533004.1	FAM83H-AS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FAM83H antisense RNA 1 (head to head)
chr10_-_62332357 Show fit	19.21	ENST00000503366.1	ANK3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin 3, node of Ranvier (ankyrin G)
chr16_-_20681177 Show fit	19.04	ENST00000524149.1	ACSM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acyl-CoA synthetase medium-chain family member 1
chr3_-_9291063 Show fit	19.03	ENST00000383836.3	SRGAP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SLIT-ROBO Rho GTPase activating protein 3
chr19_-_56988677 Show fit	19.00	ENST00000504904.3 ENST00000292069.6	ZNF667 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 667
chr17_+_43972010 Show fit	18.98	ENST00000334239.8 ENST00000446361.3	MAPT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule-associated protein tau
chr17_-_10017864 Show fit	18.79	ENST00000323816.4	GAS7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	growth arrest-specific 7
chr3_-_127542051 Show fit	18.78	ENST00000398104.1	MGLL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	monoglyceride lipase
chr20_+_57875758 Show fit	18.43	ENST00000395654.3	EDN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	endothelin 3
chr19_+_45445524 Show fit	18.20	ENST00000591600.1	APOC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein C-IV
chr12_-_6798616 Show fit	18.13	ENST00000355772.4 ENST00000417772.3 ENST00000396801.3 ENST00000396799.2	ZNF384 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 384
chr20_+_17207665 Show fit	18.01	ENST00000536609.1	PCSK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proprotein convertase subtilisin/kexin type 2
chr22_-_19512893 Show fit	18.00	ENST00000403084.1 ENST00000413119.2	CLDN5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	claudin 5
chr16_+_72090053 Show fit	17.90	ENST00000576168.2 ENST00000567185.3 ENST00000567612.2	HP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	haptoglobin
chr13_-_37494365 Show fit	17.88	ENST00000350148.5	SMAD9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SMAD family member 9
chr4_-_186732048 Show fit	17.86	ENST00000448662.2 ENST00000439049.1 ENST00000420158.1 ENST00000431808.1 ENST00000319471.9	SORBS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sorbin and SH3 domain containing 2
chr18_+_6729725 Show fit	17.71	ENST00000400091.2 ENST00000583410.1 ENST00000584387.1	ARHGAP28 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 28
chr19_+_41509851 Show fit	17.70	ENST00000593831.1 ENST00000330446.5	CYP2B6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome P450, family 2, subfamily B, polypeptide 6
chr20_+_17207636 Show fit	17.63	ENST00000262545.2	PCSK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proprotein convertase subtilisin/kexin type 2
chr3_-_127542021 Show fit	17.62	ENST00000434178.2	MGLL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	monoglyceride lipase
chr14_-_21493884 Show fit	17.42	ENST00000556974.1 ENST00000554419.1 ENST00000298687.5 ENST00000397858.1 ENST00000360463.3 ENST00000350792.3 ENST00000397847.2	NDRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDRG family member 2
chr1_-_177133818 Show fit	17.36	ENST00000424564.2 ENST00000361833.2	ASTN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	astrotactin 1
chr19_-_14887568 Show fit	17.29	ENST00000596991.2 ENST00000594294.1 ENST00000594076.1 ENST00000595839.1 ENST00000392965.3 ENST00000601345.1	EMR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	egf-like module containing, mucin-like, hormone receptor-like 2
chr14_+_71108460 Show fit	17.12	ENST00000256367.2	TTC9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tetratricopeptide repeat domain 9
chr6_-_11807277 Show fit	17.08	ENST00000379415.2	ADTRP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	androgen-dependent TFPI-regulating protein
chr11_-_89224638 Show fit	17.06	ENST00000535633.1 ENST00000263317.4	NOX4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADPH oxidase 4
chr21_-_31312230 Show fit	17.05	ENST00000399907.1 ENST00000399909.1	GRIK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, kainate 1
chr2_-_223163465 Show fit	17.00	ENST00000409828.3 ENST00000350526.4 ENST00000258387.5 ENST00000409551.3 ENST00000392069.2 ENST00000344493.4 ENST00000336840.6 ENST00000392070.2	PAX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paired box 3
chr1_+_46668994 Show fit	16.84	ENST00000371980.3	LURAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich adaptor protein 1
chr12_+_50451462 Show fit	16.83	ENST00000447966.2	ASIC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acid-sensing (proton-gated) ion channel 1
chrX_+_135229559 Show fit	16.76	ENST00000394155.2	FHL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	four and a half LIM domains 1
chr1_+_160765947 Show fit	16.73	ENST00000263285.6 ENST00000368039.2	LY9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte antigen 9
chr21_-_31311818 Show fit	16.71	ENST00000535441.1 ENST00000309434.7 ENST00000327783.4 ENST00000389124.2 ENST00000389125.3 ENST00000399913.1	GRIK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, kainate 1
chr19_-_36297348 Show fit	16.45	ENST00000589835.1	PRODH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proline dehydrogenase (oxidase) 2
chr4_-_57547870 Show fit	16.41	ENST00000381260.3 ENST00000420433.1 ENST00000554144.1 ENST00000557328.1	HOPX Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HOP homeobox
chr7_+_29519486 Show fit	16.27	ENST00000409041.4	CHN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chimerin 2
chr17_-_48207157 Show fit	16.24	ENST00000330175.4 ENST00000503131.1	SAMD14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sterile alpha motif domain containing 14
chr20_+_30946106 Show fit	16.23	ENST00000375687.4 ENST00000542461.1	ASXL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	additional sex combs like 1 (Drosophila)
chr17_-_56406117 Show fit	16.23	ENST00000268893.6 ENST00000355701.3	BZRAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	benzodiazepine receptor (peripheral) associated protein 1
chr2_+_238475217 Show fit	16.19	ENST00000165524.1	PRLH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolactin releasing hormone
chr7_+_73442102 Show fit	16.19	ENST00000445912.1 ENST00000252034.7	ELN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	elastin
chr16_+_1578674 Show fit	15.98	ENST00000253934.5	TMEM204 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 204
chr4_+_158142750 Show fit	15.94	ENST00000505888.1 ENST00000449365.1	GRIA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, AMPA 2
chr19_+_54024251 Show fit	15.75	ENST00000253144.9	ZNF331 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 331
chr16_-_21289627 Show fit	15.74	ENST00000396023.2 ENST00000415987.2	CRYM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin, mu
chr6_-_84419101 Show fit	15.60	ENST00000520302.1 ENST00000520213.1 ENST00000439399.2 ENST00000428679.2 ENST00000437520.1	SNAP91 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptosomal-associated protein, 91kDa
chr13_-_37494391 Show fit	15.59	ENST00000379826.4	SMAD9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SMAD family member 9
chr6_+_36210980 Show fit	15.55	ENST00000312917.5 ENST00000388715.3	PNPLA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	patatin-like phospholipase domain containing 1
chr19_-_36980337 Show fit	15.54	ENST00000434377.2 ENST00000424129.2 ENST00000452939.1 ENST00000427002.1	ZNF566 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 566
chr4_+_62067860 Show fit	15.48	ENST00000514591.1	LPHN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	latrophilin 3
chr7_+_73442457 Show fit	15.46	ENST00000438880.1 ENST00000414324.1 ENST00000380562.4	ELN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	elastin
chr12_+_7023491 Show fit	15.26	ENST00000541477.1 ENST00000229277.1	ENO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enolase 2 (gamma, neuronal)
chr19_-_36980455 Show fit	15.24	ENST00000454319.1 ENST00000392170.2	ZNF566 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 566
chr7_+_86273952 Show fit	15.14	ENST00000536043.1	GRM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, metabotropic 3
chr19_+_46171464 Show fit	15.02	ENST00000590918.1 ENST00000263281.3 ENST00000304207.8	GIPR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gastric inhibitory polypeptide receptor
chr7_-_50518022 Show fit	14.85	ENST00000356889.4 ENST00000420829.1 ENST00000448788.1 ENST00000395556.2 ENST00000422854.1 ENST00000435566.1 ENST00000433017.1	FIGNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fidgetin-like 1
chr10_-_30348439 Show fit	14.77	ENST00000375377.1	KIAA1462 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA1462
chr5_-_142000883 Show fit	14.75	ENST00000359370.6	FGF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibroblast growth factor 1 (acidic)
chr5_-_148033726 Show fit	14.64	ENST00000354217.2 ENST00000314512.6 ENST00000362016.2	HTR4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr3_+_186435065 Show fit	14.63	ENST00000287611.2 ENST00000265023.4	KNG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kininogen 1
chr15_+_84116106 Show fit	14.53	ENST00000535412.1 ENST00000324537.5	SH3GL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3-domain GRB2-like 3
chr17_+_1665253 Show fit	14.45	ENST00000254722.4	SERPINF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr7_+_73442487 Show fit	14.36	ENST00000380575.4 ENST00000380584.4 ENST00000458204.1 ENST00000357036.5 ENST00000417091.1 ENST00000429192.1 ENST00000442310.1 ENST00000380553.4 ENST00000380576.5 ENST00000428787.1 ENST00000320399.6	ELN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	elastin
chr4_-_8873531 Show fit	14.35	ENST00000400677.3	HMX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	H6 family homeobox 1
chr6_-_31620403 Show fit	14.25	ENST00000451898.1 ENST00000439687.2 ENST00000362049.6 ENST00000424480.1	BAG6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-associated athanogene 6
chr6_-_31514516 Show fit	14.25	ENST00000303892.5 ENST00000483251.1	ATP6V1G2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr10_-_135150367 Show fit	14.22	ENST00000368555.3 ENST00000252939.4 ENST00000368558.1 ENST00000368556.2	CALY Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcyon neuron-specific vesicular protein
chr1_+_160765884 Show fit	14.21	ENST00000392203.4	LY9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte antigen 9
chr7_-_44365020 Show fit	14.19	ENST00000395747.2 ENST00000347193.4 ENST00000346990.4 ENST00000258682.6 ENST00000353625.4 ENST00000421607.1 ENST00000424197.1 ENST00000502837.2 ENST00000350811.3 ENST00000395749.2	CAMK2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium/calmodulin-dependent protein kinase II beta
chr19_+_35630344 Show fit	14.15	ENST00000455515.2	FXYD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 1
chr12_+_79258444 Show fit	14.09	ENST00000261205.4	SYT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptotagmin I
chr8_+_79428539 Show fit	13.98	ENST00000352966.5	PKIA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr8_-_38239732 Show fit	13.91	ENST00000534155.1 ENST00000433384.2 ENST00000317025.8 ENST00000316985.3	WHSC1L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Wolf-Hirschhorn syndrome candidate 1-like 1
chr18_+_74534479 Show fit	13.83	ENST00000320610.9	ZNF236 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 236
chr11_-_32457176 Show fit	13.68	ENST00000332351.3	WT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Wilms tumor 1
chr1_+_110453514 Show fit	13.67	ENST00000369802.3 ENST00000420111.2	CSF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	colony stimulating factor 1 (macrophage)
chr5_-_11588907 Show fit	13.65	ENST00000513598.1 ENST00000503622.1	CTNND2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	catenin (cadherin-associated protein), delta 2
chrX_+_135229600 Show fit	13.64	ENST00000370690.3	FHL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	four and a half LIM domains 1
chr9_+_129089088 Show fit	13.62	ENST00000361171.3 ENST00000545391.1	MVB12B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	multivesicular body subunit 12B
chr8_-_102803163 Show fit	13.60	ENST00000523645.1 ENST00000520346.1 ENST00000220931.6 ENST00000522448.1 ENST00000522951.1 ENST00000522252.1 ENST00000519098.1	NCALD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neurocalcin delta
chr11_+_6280927 Show fit	13.57	ENST00000334619.2	CCKBR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cholecystokinin B receptor
chr11_-_70507867 Show fit	13.55	ENST00000412252.1 ENST00000409161.1 ENST00000409530.1	SHANK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3 and multiple ankyrin repeat domains 2
chr20_-_50385138 Show fit	13.53	ENST00000338821.5	ATP9A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, class II, type 9A
chr12_+_133758115 Show fit	13.51	ENST00000541009.2 ENST00000592241.1	ZNF268 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 268
chr1_+_50575292 Show fit	13.51	ENST00000371821.1 ENST00000371819.1	ELAVL4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ELAV like neuron-specific RNA binding protein 4
chr16_+_6069664 Show fit	13.51	ENST00000422070.4	RBFOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_115630900 Show fit	13.48	ENST00000537070.1 ENST00000499809.1 ENST00000514294.2 ENST00000535683.1	LINC00900 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 900
chr17_+_17942684 Show fit	13.43	ENST00000376345.3	GID4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GID complex subunit 4
chr12_+_79258547 Show fit	13.37	ENST00000457153.2	SYT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptotagmin I
chr12_+_5541267 Show fit	13.35	ENST00000423158.3	NTF3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neurotrophin 3
chr18_+_77439775 Show fit	13.20	ENST00000299543.7 ENST00000075430.7	CTDP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr11_+_17756279 Show fit	13.17	ENST00000265969.6	KCNC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr7_+_86274145 Show fit	13.16	ENST00000439827.1 ENST00000394720.2 ENST00000421579.1	GRM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, metabotropic 3
chr12_-_6798523 Show fit	13.13	ENST00000319770.3	ZNF384 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 384
chr7_-_38389573 Show fit	13.08	ENST00000390344.2	TRGV5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	T cell receptor gamma variable 5
chr18_+_29171689 Show fit	12.97	ENST00000237014.3	TTR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transthyretin
chr2_-_37193606 Show fit	12.89	ENST00000379213.2 ENST00000263918.4	STRN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	striatin, calmodulin binding protein
chr12_-_6798410 Show fit	12.89	ENST00000361959.3 ENST00000436774.2 ENST00000544482.1	ZNF384 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 384
chr9_-_72287191 Show fit	12.79	ENST00000265381.4	APBA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	amyloid beta (A4) precursor protein-binding, family A, member 1
chr17_-_37309480 Show fit	12.76	ENST00000539608.1	PLXDC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	plexin domain containing 1
chr1_+_77747656 Show fit	12.71	ENST00000354567.2	AK5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenylate kinase 5
chr1_-_149889382 Show fit	12.65	ENST00000369145.1 ENST00000369146.3	SV2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptic vesicle glycoprotein 2A
chr19_-_43709703 Show fit	12.61	ENST00000599391.1 ENST00000244295.9	PSG4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pregnancy specific beta-1-glycoprotein 4
chr14_-_54420133 Show fit	12.58	ENST00000559501.1 ENST00000558984.1	BMP4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	bone morphogenetic protein 4
chr15_+_84115868 Show fit	12.58	ENST00000427482.2	SH3GL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3-domain GRB2-like 3
chr11_-_32457075 Show fit	12.57	ENST00000448076.3	WT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Wilms tumor 1
chr1_+_228353495 Show fit	12.55	ENST00000366711.3	IBA57 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr11_+_66278080 Show fit	12.47	ENST00000318312.7 ENST00000526815.1 ENST00000537537.1 ENST00000525809.1 ENST00000455748.2 ENST00000393994.2	BBS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Bardet-Biedl syndrome 1
chr3_+_185080908 Show fit	12.40	ENST00000265026.3	MAP3K13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase kinase kinase 13

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
32.4	194.7	GO:0010734	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
23.7	71.1	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
18.8	94.1	GO:0060611	positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
15.5	92.9	GO:0070560	protein secretion by platelet(GO:0070560)
14.8	74.1	GO:0034443	negative regulation of lipoprotein oxidation(GO:0034443)
12.6	37.9	GO:1904617	negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
12.1	36.4	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
11.4	57.1	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
10.8	32.3	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
9.9	29.8	GO:1904425	negative regulation of GTP binding(GO:1904425)
9.8	39.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
9.2	27.5	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
9.1	27.3	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
8.3	25.0	GO:1901876	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
8.3	58.3	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
8.1	16.2	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
7.8	39.2	GO:0071279	cellular response to cobalt ion(GO:0071279)
7.8	23.3	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
7.6	30.3	GO:0072299	posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
7.4	22.1	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621)
7.1	35.6	GO:0030070	insulin processing(GO:0030070)
7.0	20.9	GO:1904328	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
6.7	20.2	GO:0061537	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
6.5	45.7	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
6.4	19.3	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
6.2	18.6	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
6.1	36.6	GO:0061518	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
6.0	17.9	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
5.7	17.1	GO:0048691	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
5.4	10.9	GO:0055073	cadmium ion homeostasis(GO:0055073)
5.3	21.3	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
5.3	21.2	GO:0034959	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
5.3	5.3	GO:0099545	trans-synaptic signaling by trans-synaptic complex(GO:0099545)
5.2	36.3	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
5.0	20.2	GO:0006710	androgen catabolic process(GO:0006710)
4.9	29.5	GO:0006196	AMP catabolic process(GO:0006196)
4.8	28.9	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
4.8	19.2	GO:1900827	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
4.7	19.0	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
4.7	14.1	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
4.6	18.5	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
4.6	23.0	GO:0099538	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
4.6	27.7	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
4.5	13.5	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
4.4	13.2	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
4.3	47.4	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
4.2	12.7	GO:0006172	ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
4.1	4.1	GO:0045807	positive regulation of endocytosis(GO:0045807)
4.0	12.0	GO:2000360	negative regulation of binding of sperm to zona pellucida(GO:2000360)
3.9	7.8	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
3.8	11.5	GO:0042938	dipeptide transport(GO:0042938)
3.7	11.1	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
3.6	7.2	GO:0009957	epidermal cell fate specification(GO:0009957)
3.5	17.3	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
3.5	13.8	GO:0001678	cellular glucose homeostasis(GO:0001678)
3.4	37.1	GO:0090232	peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
3.3	16.7	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
3.3	26.6	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
3.2	9.5	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
3.1	6.3	GO:0031133	regulation of axon diameter(GO:0031133)
3.1	49.7	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
3.1	6.2	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
3.0	6.1	GO:0061010	gall bladder development(GO:0061010)
3.0	57.6	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
3.0	8.9	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
3.0	8.9	GO:0044179	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
3.0	11.8	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
2.9	139.2	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
2.9	8.7	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
2.8	11.4	GO:1990936	metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
2.8	8.5	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
2.8	5.7	GO:2000364	regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
2.8	8.4	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
2.8	8.3	GO:0008078	mesoderm migration involved in gastrulation(GO:0007509) mesodermal cell migration(GO:0008078)
2.8	5.5	GO:2000809	positive regulation of synaptic vesicle clustering(GO:2000809)
2.7	16.5	GO:0010133	proline catabolic process to glutamate(GO:0010133)
2.7	27.4	GO:0042940	D-amino acid transport(GO:0042940)
2.7	8.1	GO:0030046	parallel actin filament bundle assembly(GO:0030046) establishment of meiotic spindle localization(GO:0051295)
2.7	21.4	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
2.6	13.2	GO:0021759	globus pallidus development(GO:0021759)
2.6	18.4	GO:0050915	sensory perception of sour taste(GO:0050915)
2.6	36.2	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
2.6	12.8	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
2.5	7.5	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
2.5	50.0	GO:0090128	regulation of synapse maturation(GO:0090128)
2.5	27.4	GO:1902172	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
2.5	7.4	GO:1902722	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) positive regulation of prolactin secretion(GO:1902722)
2.4	7.2	GO:2001301	cellular response to interleukin-13(GO:0035963) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
2.3	2.3	GO:0032276	regulation of gonadotropin secretion(GO:0032276) negative regulation of gonadotropin secretion(GO:0032277) positive regulation of gonadotropin secretion(GO:0032278) interferon-gamma biosynthetic process(GO:0042095) regulation of interferon-gamma biosynthetic process(GO:0045072) negative regulation of interferon-gamma biosynthetic process(GO:0045077) negative regulation of B cell differentiation(GO:0045578) negative regulation of macrophage differentiation(GO:0045650) regulation of follicle-stimulating hormone secretion(GO:0046880) positive regulation of follicle-stimulating hormone secretion(GO:0046881) negative regulation of follicle-stimulating hormone secretion(GO:0046882) follicle-stimulating hormone secretion(GO:0046884)
2.3	7.0	GO:0003099	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
2.3	32.5	GO:0035878	nail development(GO:0035878)
2.3	18.0	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
2.2	6.7	GO:1904300	positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
2.2	20.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
2.2	6.6	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
2.2	28.7	GO:0070327	thyroid hormone transport(GO:0070327)
2.2	13.1	GO:0006540	glutamate decarboxylation to succinate(GO:0006540)
2.2	10.8	GO:0018125	peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385)
2.1	6.4	GO:0032289	central nervous system myelin formation(GO:0032289)
2.1	23.3	GO:0015886	heme transport(GO:0015886)
2.1	6.3	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
2.0	6.1	GO:0046440	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
2.0	6.0	GO:0031049	mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
2.0	7.9	GO:0050712	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
2.0	17.6	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
1.9	5.8	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
1.9	7.6	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
1.9	5.7	GO:0060164	amygdala development(GO:0021764) regulation of timing of neuron differentiation(GO:0060164)
1.9	7.6	GO:1905229	cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
1.9	41.5	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
1.9	5.6	GO:0033341	regulation of collagen binding(GO:0033341)
1.9	18.8	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
1.8	20.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.8	7.3	GO:0021997	response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
1.8	21.6	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
1.8	5.4	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
1.8	5.3	GO:2000171	negative regulation of dendrite development(GO:2000171)
1.7	34.7	GO:0061154	endothelial tube morphogenesis(GO:0061154)
1.7	3.4	GO:0086068	Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
1.7	6.9	GO:0090527	actin filament reorganization(GO:0090527)
1.7	8.4	GO:0080009	mRNA methylation(GO:0080009)
1.7	6.7	GO:0061196	fungiform papilla development(GO:0061196)
1.6	8.1	GO:0036369	transcription factor catabolic process(GO:0036369)
1.6	3.2	GO:0030259	lipid glycosylation(GO:0030259)
1.6	21.9	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
1.6	1.6	GO:0072197	ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
1.6	7.8	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
1.5	10.6	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
1.5	4.5	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.5	7.4	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.5	45.4	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.5	21.9	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.4	18.7	GO:0042738	exogenous drug catabolic process(GO:0042738)
1.4	8.5	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
1.4	5.6	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
1.4	14.9	GO:0071625	vocalization behavior(GO:0071625)
1.3	44.1	GO:0050667	homocysteine metabolic process(GO:0050667)
1.3	3.8	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
1.2	16.2	GO:0002021	response to dietary excess(GO:0002021)
1.2	5.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
1.2	7.4	GO:0048263	determination of dorsal identity(GO:0048263)
1.2	9.8	GO:2000773	negative regulation of cellular senescence(GO:2000773)
1.2	13.5	GO:0000050	urea cycle(GO:0000050)
1.2	7.2	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.2	4.8	GO:0003335	corneocyte development(GO:0003335)
1.2	15.4	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.2	3.5	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.2	5.8	GO:0071286	cellular response to magnesium ion(GO:0071286)
1.2	25.5	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
1.1	20.5	GO:0007021	tubulin complex assembly(GO:0007021)
1.1	17.0	GO:0014029	neural crest formation(GO:0014029)
1.1	2.2	GO:0001575	globoside metabolic process(GO:0001575)
1.1	4.4	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
1.1	18.4	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
1.1	5.4	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.1	4.3	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
1.1	5.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
1.1	7.4	GO:0042428	serotonin metabolic process(GO:0042428)
1.0	5.2	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
1.0	25.9	GO:0032098	regulation of appetite(GO:0032098)
1.0	58.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
1.0	21.5	GO:0050930	induction of positive chemotaxis(GO:0050930)
1.0	10.1	GO:0035641	locomotory exploration behavior(GO:0035641)
1.0	36.1	GO:0030517	negative regulation of axon extension(GO:0030517)
1.0	9.0	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.0	2.0	GO:0043932	ossification involved in bone remodeling(GO:0043932)
1.0	6.0	GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
1.0	7.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
1.0	4.0	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.0	10.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
1.0	2.0	GO:1904954	Spemann organizer formation(GO:0060061) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
1.0	6.8	GO:0001951	intestinal D-glucose absorption(GO:0001951)
1.0	4.9	GO:0042420	dopamine catabolic process(GO:0042420)
1.0	4.8	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.0	56.8	GO:0060997	dendritic spine morphogenesis(GO:0060997)
1.0	27.9	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.0	13.4	GO:0007158	neuron cell-cell adhesion(GO:0007158)
1.0	9.5	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.9	10.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.9	15.9	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.9	3.7	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.9	3.7	GO:0061056	sclerotome development(GO:0061056)
0.9	10.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.9	2.8	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.9	5.6	GO:0098535	de novo centriole assembly(GO:0098535)
0.9	69.2	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.9	6.4	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.9	12.8	GO:0021510	spinal cord development(GO:0021510)
0.9	13.6	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.9	6.3	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.9	24.2	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.9	2.7	GO:0032581	ER-dependent peroxisome organization(GO:0032581)
0.9	10.6	GO:0035372	protein localization to microtubule(GO:0035372)
0.9	9.7	GO:0060004	reflex(GO:0060004)
0.9	26.5	GO:0019433	triglyceride catabolic process(GO:0019433)
0.9	2.6	GO:2001023	regulation of response to drug(GO:2001023)
0.9	4.3	GO:0071233	cellular response to leucine(GO:0071233)
0.9	12.9	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.9	6.9	GO:0035107	appendage morphogenesis(GO:0035107) limb morphogenesis(GO:0035108)
0.9	2.6	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.9	23.9	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.8	4.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.8	11.8	GO:0097264	self proteolysis(GO:0097264)
0.8	16.0	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.8	28.6	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.8	2.5	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.8	7.5	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.8	5.0	GO:0051480	regulation of cytosolic calcium ion concentration(GO:0051480)
0.8	27.4	GO:0050885	neuromuscular process controlling balance(GO:0050885)
0.8	3.3	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.8	5.0	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.8	5.7	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.8	49.8	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.8	8.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.8	6.4	GO:0034587	piRNA metabolic process(GO:0034587)
0.8	7.2	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.8	2.4	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.8	7.1	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.8	15.7	GO:0016601	Rac protein signal transduction(GO:0016601)
0.8	3.9	GO:0021861	forebrain radial glial cell differentiation(GO:0021861) odontoblast differentiation(GO:0071895)
0.8	3.1	GO:0071321	positive regulation of oocyte development(GO:0060282) cellular response to cGMP(GO:0071321)
0.8	7.0	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.8	5.4	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) parathyroid gland development(GO:0060017) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.8	22.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.8	4.5	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.7	16.9	GO:0006067	ethanol metabolic process(GO:0006067)
0.7	2.9	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.7	4.3	GO:0048511	rhythmic process(GO:0048511)
0.7	32.2	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.7	10.3	GO:0007625	grooming behavior(GO:0007625)
0.7	15.8	GO:0007368	determination of left/right symmetry(GO:0007368)
0.7	14.9	GO:0007141	male meiosis I(GO:0007141)
0.7	2.7	GO:1903597	negative regulation of gap junction assembly(GO:1903597)
0.7	11.4	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.7	28.8	GO:0097178	ruffle assembly(GO:0097178)
0.7	4.0	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.7	32.0	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.7	3.9	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.7	4.6	GO:0005980	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.6	13.5	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.6	8.9	GO:0032094	response to food(GO:0032094)
0.6	7.6	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.6	1.8	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.6	16.4	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.6	4.8	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.6	16.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.6	4.8	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.6	3.6	GO:0008544	epidermis development(GO:0008544)
0.6	6.5	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
0.6	2.3	GO:0007341	penetration of zona pellucida(GO:0007341)
0.6	2.9	GO:0001766	membrane raft polarization(GO:0001766) regulation of myeloid dendritic cell activation(GO:0030885) membrane raft distribution(GO:0031580)
0.6	5.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.6	9.1	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.6	7.9	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.6	5.0	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.6	5.0	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.6	6.7	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.6	1.7	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.5	14.2	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.5	4.9	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.5	18.1	GO:0090383	phagosome acidification(GO:0090383)
0.5	7.4	GO:0001522	pseudouridine synthesis(GO:0001522)
0.5	3.7	GO:0016322	neuron remodeling(GO:0016322)
0.5	14.3	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.5	3.2	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.5	15.2	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.5	18.9	GO:0035136	forelimb morphogenesis(GO:0035136)
0.5	14.6	GO:0006783	heme biosynthetic process(GO:0006783)
0.5	5.2	GO:0032962	regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.5	4.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.5	2.1	GO:0006568	tryptophan metabolic process(GO:0006568)
0.5	18.9	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5	31.2	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.5	6.1	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.5	5.0	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.5	7.5	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.5	6.5	GO:0010039	response to iron ion(GO:0010039)
0.5	12.5	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.5	5.5	GO:0048813	dendrite morphogenesis(GO:0048813)
0.5	2.9	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586)
0.5	7.4	GO:0007049	cell cycle(GO:0007049)
0.5	1.0	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.5	3.4	GO:0007379	segment specification(GO:0007379)
0.5	12.0	GO:0010107	potassium ion import(GO:0010107)
0.5	2.9	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.5	23.4	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.5	4.8	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.5	1.9	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.5	1.4	GO:0006726	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.5	18.9	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.5	1.4	GO:0032223	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.5	6.6	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.5	2.3	GO:0009624	response to nematode(GO:0009624)
0.4	10.1	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.4	2.2	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.4	11.1	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.4	3.8	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.4	8.9	GO:0008038	neuron recognition(GO:0008038)
0.4	1.6	GO:0048050	post-embryonic eye morphogenesis(GO:0048050) post-embryonic organ morphogenesis(GO:0048563)
0.4	2.8	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.4	1.6	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.4	2.8	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.4	7.4	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.4	13.6	GO:0050771	negative regulation of axonogenesis(GO:0050771)
0.4	5.5	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.4	7.7	GO:0048745	smooth muscle tissue development(GO:0048745)
0.3	0.7	GO:0033686	regulation of luteinizing hormone secretion(GO:0033684) positive regulation of luteinizing hormone secretion(GO:0033686)
0.3	4.8	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3	4.7	GO:0021681	cerebellar granular layer development(GO:0021681)
0.3	8.2	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.3	7.1	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.3	1.3	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3	1.6	GO:0032264	IMP salvage(GO:0032264)
0.3	8.6	GO:0030488	tRNA methylation(GO:0030488)
0.3	1.6	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3	12.2	GO:0007631	feeding behavior(GO:0007631)
0.3	2.5	GO:1903859	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.3	5.3	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.3	0.9	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.3	13.3	GO:0006942	regulation of striated muscle contraction(GO:0006942)
0.3	5.3	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.3	2.5	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.3	6.4	GO:0030199	collagen fibril organization(GO:0030199)
0.3	4.1	GO:0032196	transposition(GO:0032196)
0.3	2.3	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.3	6.6	GO:0001525	angiogenesis(GO:0001525)
0.3	12.6	GO:0030279	negative regulation of ossification(GO:0030279)
0.3	7.2	GO:0003338	metanephros morphogenesis(GO:0003338)
0.3	2.5	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3	5.8	GO:0032411	positive regulation of transporter activity(GO:0032411)
0.3	1.6	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3	3.8	GO:0051764	actin crosslink formation(GO:0051764)
0.3	6.7	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3	4.3	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.3	7.2	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3	2.6	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.3	8.3	GO:0006954	inflammatory response(GO:0006954)
0.3	13.6	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.3	8.4	GO:0051260	protein homooligomerization(GO:0051260)
0.3	3.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.3	1.8	GO:0044245	polysaccharide digestion(GO:0044245)
0.3	0.5	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2	4.7	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.2	6.0	GO:0050779	RNA destabilization(GO:0050779)
0.2	2.9	GO:0030321	transepithelial chloride transport(GO:0030321)
0.2	5.5	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.2	3.8	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.2	4.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.2	2.5	GO:0051932	synaptic transmission, GABAergic(GO:0051932)
0.2	3.6	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.2	7.2	GO:0018149	peptide cross-linking(GO:0018149)
0.2	4.4	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.2	1.7	GO:0035095	behavioral response to nicotine(GO:0035095)
0.2	15.6	GO:0006024	aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.2	1.7	GO:0038092	nodal signaling pathway(GO:0038092)
0.2	7.7	GO:0042472	inner ear morphogenesis(GO:0042472)
0.2	1.9	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.2	11.5	GO:0016266	O-glycan processing(GO:0016266)
0.2	1.0	GO:0035524	proline transmembrane transport(GO:0035524)
0.2	3.9	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.2	1.5	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.2	6.2	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.2	3.1	GO:0097120	receptor localization to synapse(GO:0097120)
0.2	2.4	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2	0.5	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.2	4.4	GO:0042461	photoreceptor cell development(GO:0042461)
0.2	1.5	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2	9.6	GO:0030282	bone mineralization(GO:0030282)
0.2	6.8	GO:0006839	mitochondrial transport(GO:0006839)
0.2	13.0	GO:0031295	T cell costimulation(GO:0031295)
0.1	4.0	GO:0016579	protein deubiquitination(GO:0016579)
0.1	1.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	1.0	GO:0051259	protein oligomerization(GO:0051259)
0.1	4.8	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	0.4	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	6.0	GO:0001578	microtubule bundle formation(GO:0001578)
0.1	1.1	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.1	6.2	GO:0006735	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1	1.3	GO:0015732	prostaglandin transport(GO:0015732)
0.1	1.2	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	3.3	GO:0008285	negative regulation of cell proliferation(GO:0008285)
0.1	5.2	GO:0061045	negative regulation of wound healing(GO:0061045)
0.1	2.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	3.3	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.1	5.2	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1	5.7	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	0.4	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1	6.6	GO:0055072	iron ion homeostasis(GO:0055072)
0.1	1.7	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	2.2	GO:0031214	biomineral tissue development(GO:0031214)
0.1	2.8	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1	1.2	GO:0043010	camera-type eye development(GO:0043010)
0.1	1.3	GO:0097435	fibril organization(GO:0097435)
0.1	0.1	GO:0010644	cell communication by electrical coupling(GO:0010644)
0.1	2.9	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.1	1.6	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.1	24.9	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.1	12.6	GO:0031032	actomyosin structure organization(GO:0031032)
0.1	9.9	GO:0051262	protein tetramerization(GO:0051262)
0.1	1.3	GO:0001502	cartilage condensation(GO:0001502)
0.1	0.4	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	1.2	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.1	2.3	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.1	2.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.6	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.1	0.5	GO:0061635	regulation of protein complex stability(GO:0061635)
0.1	1.1	GO:0050905	neuromuscular process(GO:0050905)
0.1	1.4	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.1	7.8	GO:2001252	positive regulation of chromosome organization(GO:2001252)
0.1	1.5	GO:0048536	spleen development(GO:0048536)
0.1	2.7	GO:0036297	interstrand cross-link repair(GO:0036297)
0.1	5.0	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1	1.8	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	2.4	GO:0016525	negative regulation of angiogenesis(GO:0016525)
0.1	3.2	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.1	4.0	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	3.7	GO:0009142	nucleoside triphosphate biosynthetic process(GO:0009142)
0.0	3.4	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.0	2.9	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.0	1.1	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.8	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.6	GO:0051017	actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0	0.4	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	1.8	GO:0042255	ribosome assembly(GO:0042255)
0.0	1.4	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.0	0.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	1.1	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.9	GO:0006836	neurotransmitter transport(GO:0006836)
0.0	0.6	GO:0048738	cardiac muscle tissue development(GO:0048738)
0.0	1.0	GO:0008643	carbohydrate transport(GO:0008643)
0.0	0.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
19.2	95.8	GO:0098843	postsynaptic endocytic zone(GO:0098843)
15.7	94.1	GO:1990682	CSF1-CSF1R complex(GO:1990682)
14.9	44.6	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
14.3	57.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
14.2	71.1	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
9.7	194.7	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
8.9	26.6	GO:0072534	perineuronal net(GO:0072534)
8.0	80.2	GO:0071953	elastic fiber(GO:0071953)
5.5	27.5	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
5.3	112.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
5.3	21.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
5.3	21.2	GO:0031302	intrinsic component of endosome membrane(GO:0031302)
4.6	27.3	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
4.5	17.9	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
4.0	36.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
3.8	19.0	GO:0045298	tubulin complex(GO:0045298)
3.3	39.2	GO:0043203	axon hillock(GO:0043203)
3.2	9.7	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
3.0	50.3	GO:0043020	NADPH oxidase complex(GO:0043020)
2.9	8.6	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
2.8	8.4	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
2.7	13.4	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
2.6	10.6	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
2.5	7.4	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
2.3	9.1	GO:0070876	SOSS complex(GO:0070876)
2.3	6.8	GO:0097453	mesaxon(GO:0097453) ensheathing process(GO:1990015)
2.2	8.7	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
2.1	6.4	GO:0071546	pi-body(GO:0071546)
2.1	19.3	GO:1990761	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
2.1	6.4	GO:0005588	collagen type V trimer(GO:0005588)
2.1	10.6	GO:0005602	complement component C1 complex(GO:0005602)
2.1	12.8	GO:1990769	proximal neuron projection(GO:1990769)
2.1	20.9	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
2.0	7.9	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
1.9	13.6	GO:0000813	ESCRT I complex(GO:0000813)
1.9	11.3	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
1.9	5.6	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
1.9	5.6	GO:0098536	deuterosome(GO:0098536)
1.8	27.5	GO:0042627	chylomicron(GO:0042627)
1.8	10.8	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
1.7	20.8	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.7	13.6	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
1.7	5.0	GO:0097059	CNTFR-CLCF1 complex(GO:0097059)
1.6	20.9	GO:0097433	dense body(GO:0097433)
1.6	36.9	GO:0071141	SMAD protein complex(GO:0071141)
1.6	47.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
1.6	10.9	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
1.5	12.2	GO:0072687	meiotic spindle(GO:0072687)
1.5	13.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
1.4	12.5	GO:0034464	BBSome(GO:0034464)
1.4	2.8	GO:0032009	early phagosome(GO:0032009)
1.4	5.4	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
1.4	5.4	GO:0032279	asymmetric synapse(GO:0032279)
1.3	20.5	GO:0097512	cardiac myofibril(GO:0097512)
1.3	70.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
1.2	27.9	GO:0030056	hemidesmosome(GO:0030056)
1.2	30.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
1.1	27.5	GO:0030673	axolemma(GO:0030673)
1.1	26.9	GO:0071565	nBAF complex(GO:0071565)
1.0	15.6	GO:0005905	clathrin-coated pit(GO:0005905)
1.0	18.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
1.0	6.0	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
1.0	12.0	GO:0034362	low-density lipoprotein particle(GO:0034362)
1.0	14.9	GO:0005883	neurofilament(GO:0005883)
1.0	4.9	GO:0016600	flotillin complex(GO:0016600)
0.9	43.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.9	22.1	GO:0016580	Sin3 complex(GO:0016580)
0.9	7.3	GO:0044294	dendritic growth cone(GO:0044294)
0.9	132.4	GO:0043204	perikaryon(GO:0043204)
0.9	12.7	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.9	19.6	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.8	10.5	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.8	57.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.8	20.0	GO:0034451	centriolar satellite(GO:0034451)
0.8	5.5	GO:0060091	kinocilium(GO:0060091)
0.8	11.6	GO:0030478	actin cap(GO:0030478)
0.8	18.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.7	9.5	GO:0005858	axonemal dynein complex(GO:0005858)
0.7	4.3	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.7	46.8	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.7	67.5	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.7	5.5	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.7	86.7	GO:0031901	early endosome membrane(GO:0031901)
0.7	2.0	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.7	7.2	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6	4.5	GO:0097209	epidermal lamellar body(GO:0097209)
0.6	1.9	GO:0060198	clathrin-sculpted vesicle(GO:0060198)
0.6	18.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.6	7.7	GO:0008385	IkappaB kinase complex(GO:0008385)
0.6	2.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.6	5.8	GO:0043198	dendritic shaft(GO:0043198)
0.5	54.3	GO:0044306	neuron projection terminus(GO:0044306)
0.5	5.4	GO:0031209	SCAR complex(GO:0031209)
0.5	136.2	GO:0045211	postsynaptic membrane(GO:0045211)
0.5	4.6	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.5	9.9	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.5	24.7	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.5	3.8	GO:0005610	laminin-5 complex(GO:0005610)
0.5	13.2	GO:0051233	spindle midzone(GO:0051233)
0.4	4.0	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4	11.3	GO:0009986	cell surface(GO:0009986)
0.4	3.9	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.4	5.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.4	3.4	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.4	8.0	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.4	56.5	GO:0030027	lamellipodium(GO:0030027)
0.4	11.5	GO:0098862	cluster of actin-based cell projections(GO:0098862)
0.4	7.8	GO:0009897	external side of plasma membrane(GO:0009897)
0.4	68.2	GO:0005802	trans-Golgi network(GO:0005802)
0.4	2.5	GO:0031616	spindle pole centrosome(GO:0031616)
0.4	39.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.3	4.4	GO:0033268	node of Ranvier(GO:0033268)
0.3	14.8	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3	34.9	GO:0005796	Golgi lumen(GO:0005796)
0.3	3.6	GO:0097524	sperm plasma membrane(GO:0097524)
0.3	52.2	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.3	39.6	GO:0030426	growth cone(GO:0030426)
0.3	47.6	GO:0031225	anchored component of membrane(GO:0031225)
0.3	40.3	GO:0098793	presynapse(GO:0098793)
0.3	65.5	GO:0019898	extrinsic component of membrane(GO:0019898)
0.3	12.9	GO:0016235	aggresome(GO:0016235)
0.3	15.3	GO:0031526	brush border membrane(GO:0031526)
0.3	2.7	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3	7.3	GO:0032421	stereocilium bundle(GO:0032421)
0.3	3.2	GO:0031906	late endosome lumen(GO:0031906)
0.3	5.0	GO:0030658	transport vesicle membrane(GO:0030658)
0.3	58.8	GO:0043025	neuronal cell body(GO:0043025)
0.2	22.4	GO:0030424	axon(GO:0030424)
0.2	7.5	GO:0032587	ruffle membrane(GO:0032587)
0.2	17.7	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.2	6.4	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.2	9.9	GO:0008023	transcription elongation factor complex(GO:0008023)
0.2	2.6	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.2	1.3	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.2	2.3	GO:0001673	male germ cell nucleus(GO:0001673)
0.2	0.5	GO:0030008	TRAPP complex(GO:0030008)
0.2	1.3	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.2	12.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.2	91.6	GO:0000139	Golgi membrane(GO:0000139)
0.1	7.2	GO:0001533	cornified envelope(GO:0001533)
0.1	2.3	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.1	0.9	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	8.2	GO:0070821	tertiary granule membrane(GO:0070821)
0.1	47.6	GO:0016607	nuclear speck(GO:0016607)
0.1	5.8	GO:0044297	cell body(GO:0044297)
0.1	7.5	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1	4.8	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.1	5.5	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	8.7	GO:0030496	midbody(GO:0030496)
0.1	6.6	GO:0005884	actin filament(GO:0005884)
0.1	13.4	GO:0072562	blood microparticle(GO:0072562)
0.1	1.6	GO:0032982	myosin filament(GO:0032982)
0.1	1.5	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	1.3	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	2.7	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	0.5	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	4.9	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	119.9	GO:0031224	intrinsic component of membrane(GO:0031224)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.3	91.8	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
11.8	71.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
10.1	30.2	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
7.9	95.4	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
7.8	39.1	GO:0031708	endothelin B receptor binding(GO:0031708)
7.5	22.5	GO:0015439	heme-transporting ATPase activity(GO:0015439)
6.2	18.6	GO:0004951	cholecystokinin receptor activity(GO:0004951)
6.1	42.7	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
6.1	30.3	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
5.7	28.3	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
5.5	22.1	GO:0035939	microsatellite binding(GO:0035939)
5.5	55.3	GO:0019826	oxygen sensor activity(GO:0019826)
5.5	27.5	GO:0030348	syntaxin-3 binding(GO:0030348)
5.5	27.3	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
5.4	32.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
5.4	32.3	GO:0042577	lipid phosphatase activity(GO:0042577)
5.2	25.9	GO:0001594	trace-amine receptor activity(GO:0001594)
5.0	20.2	GO:0015375	glycine:sodium symporter activity(GO:0015375)
4.7	19.0	GO:0099609	microtubule lateral binding(GO:0099609)
4.6	23.0	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
4.5	13.6	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
4.5	27.0	GO:0005119	smoothened binding(GO:0005119)
4.5	58.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
4.3	17.3	GO:0004047	aminomethyltransferase activity(GO:0004047)
4.1	12.4	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
4.1	16.5	GO:0004657	proline dehydrogenase activity(GO:0004657)
3.9	15.7	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
3.9	15.4	GO:0005151	interleukin-1, Type II receptor binding(GO:0005151)
3.8	11.5	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
3.7	203.2	GO:0017080	sodium channel regulator activity(GO:0017080)
3.7	18.4	GO:0044736	acid-sensing ion channel activity(GO:0044736)
3.6	10.9	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
3.5	31.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
3.4	17.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
3.3	13.4	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
3.3	66.4	GO:0051787	misfolded protein binding(GO:0051787)
3.2	9.7	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
3.2	157.6	GO:0030507	spectrin binding(GO:0030507)
3.1	79.5	GO:0017075	syntaxin-1 binding(GO:0017075)
3.0	24.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
3.0	17.9	GO:0030492	hemoglobin binding(GO:0030492)
3.0	8.9	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
3.0	11.8	GO:0097603	temperature-gated ion channel activity(GO:0097603)
2.9	8.6	GO:0016429	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
2.8	8.5	GO:0050501	hyaluronan synthase activity(GO:0050501)
2.8	19.8	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
2.8	8.4	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
2.8	13.9	GO:0070697	activin receptor binding(GO:0070697)
2.8	8.3	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
2.8	8.3	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
2.6	10.6	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
2.6	13.2	GO:0008420	CTD phosphatase activity(GO:0008420)
2.6	34.0	GO:0038132	neuregulin binding(GO:0038132)
2.6	23.3	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
2.5	42.2	GO:0038191	neuropilin binding(GO:0038191)
2.4	7.2	GO:0047977	hepoxilin-epoxide hydrolase activity(GO:0047977)
2.4	7.1	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
2.3	49.3	GO:0031005	filamin binding(GO:0031005)
2.3	7.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
2.2	8.9	GO:0042954	lipoprotein transporter activity(GO:0042954)
2.2	30.9	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
2.2	8.7	GO:0032145	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
2.2	13.0	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
2.1	14.9	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
2.1	23.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
2.1	14.6	GO:0031681	G-protein beta-subunit binding(GO:0031681)
2.0	8.1	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
2.0	6.0	GO:0035501	MH1 domain binding(GO:0035501)
2.0	6.0	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
1.9	11.3	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
1.9	13.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
1.8	9.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
1.8	17.6	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
1.7	15.4	GO:0048495	Roundabout binding(GO:0048495)
1.7	6.9	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.7	16.9	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
1.7	5.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
1.7	6.6	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
1.6	11.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
1.6	13.0	GO:0070324	thyroid hormone binding(GO:0070324)
1.6	4.9	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
1.6	6.4	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
1.6	20.9	GO:0008517	folic acid transporter activity(GO:0008517)
1.6	7.9	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
1.6	7.9	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
1.6	20.2	GO:0036122	BMP binding(GO:0036122)
1.5	4.6	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
1.5	6.2	GO:0004948	calcitonin receptor activity(GO:0004948)
1.5	16.8	GO:0051430	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.5	30.4	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
1.5	4.5	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
1.5	7.4	GO:0004994	somatostatin receptor activity(GO:0004994)
1.5	32.5	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
1.5	5.8	GO:0048763	calcium-induced calcium release activity(GO:0048763)
1.4	18.3	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
1.4	5.5	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
1.4	16.4	GO:0004017	adenylate kinase activity(GO:0004017)
1.3	6.7	GO:0004992	platelet activating factor receptor activity(GO:0004992)
1.3	1.3	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.3	40.5	GO:0043015	gamma-tubulin binding(GO:0043015)
1.3	3.8	GO:0004961	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.3	13.8	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
1.3	23.8	GO:0044548	S100 protein binding(GO:0044548)
1.2	21.8	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
1.2	30.3	GO:0004383	guanylate cyclase activity(GO:0004383)
1.2	26.5	GO:0004806	triglyceride lipase activity(GO:0004806)
1.2	19.3	GO:0048156	tau protein binding(GO:0048156)
1.2	23.5	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
1.2	7.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
1.2	10.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
1.2	5.8	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
1.1	10.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
1.1	11.2	GO:0015643	toxic substance binding(GO:0015643)
1.1	7.6	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
1.1	5.4	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
1.1	6.5	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.1	5.4	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
1.1	7.4	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.0	3.1	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.0	16.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
1.0	5.0	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
1.0	26.9	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.0	16.9	GO:0071855	neuropeptide receptor binding(GO:0071855)
1.0	2.0	GO:0016015	morphogen activity(GO:0016015)
1.0	12.6	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
1.0	43.8	GO:0003785	actin monomer binding(GO:0003785)
0.9	17.7	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.9	3.7	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.9	7.3	GO:0004111	creatine kinase activity(GO:0004111)
0.9	2.7	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.9	10.8	GO:0031489	myosin V binding(GO:0031489)
0.9	5.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.9	5.2	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.9	121.5	GO:0005319	lipid transporter activity(GO:0005319)
0.9	15.6	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.9	10.3	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.8	16.8	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.8	5.8	GO:0004046	aminoacylase activity(GO:0004046)
0.8	5.8	GO:0017022	myosin binding(GO:0017022)
0.8	4.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.8	19.2	GO:0071837	HMG box domain binding(GO:0071837)
0.8	12.0	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.8	5.5	GO:0045159	myosin II binding(GO:0045159)
0.8	12.5	GO:0097109	neuroligin family protein binding(GO:0097109)
0.8	5.4	GO:0043559	insulin binding(GO:0043559)
0.8	8.4	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.8	7.6	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.8	7.5	GO:0019215	intermediate filament binding(GO:0019215)
0.7	6.6	GO:0032051	clathrin light chain binding(GO:0032051)
0.7	5.7	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.7	13.6	GO:0043014	alpha-tubulin binding(GO:0043014)
0.7	77.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.7	66.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.7	26.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.7	2.1	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.7	26.3	GO:0017046	peptide hormone binding(GO:0017046)
0.7	6.7	GO:0030882	lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.6	1.9	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.6	9.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.6	7.4	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.6	1.8	GO:0047783	steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.6	1.8	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.6	3.0	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.6	23.6	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.6	18.1	GO:0005212	structural constituent of eye lens(GO:0005212)
0.6	18.1	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.6	2.9	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.6	8.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6	6.9	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6	9.5	GO:0045505	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) dynein intermediate chain binding(GO:0045505)
0.5	6.6	GO:0070412	R-SMAD binding(GO:0070412)
0.5	4.9	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.5	10.3	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.5	2.7	GO:0070573	metallodipeptidase activity(GO:0070573)
0.5	3.8	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.5	5.3	GO:0048185	activin binding(GO:0048185)
0.5	4.8	GO:0005542	folic acid binding(GO:0005542)
0.5	11.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.5	9.9	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5	5.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.5	5.7	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.5	2.5	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.5	4.4	GO:0017081	chloride channel regulator activity(GO:0017081)
0.5	7.8	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.5	59.0	GO:0042826	histone deacetylase binding(GO:0042826)
0.5	26.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.5	156.3	GO:0005096	GTPase activator activity(GO:0005096)
0.5	2.3	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.5	10.5	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.5	24.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5	3.2	GO:0071253	connexin binding(GO:0071253)
0.4	11.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4	6.2	GO:0033691	sialic acid binding(GO:0033691)
0.4	6.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.4	2.2	GO:0097016	L27 domain binding(GO:0097016)
0.4	15.1	GO:0005109	frizzled binding(GO:0005109)
0.4	18.8	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.4	7.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.4	2.9	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.4	3.5	GO:0004969	histamine receptor activity(GO:0004969)
0.4	2.3	GO:0034711	inhibin binding(GO:0034711)
0.4	38.4	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.4	5.4	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4	8.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.4	7.8	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.4	5.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.4	16.2	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.3	4.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.3	2.8	GO:0035325	Toll-like receptor binding(GO:0035325)
0.3	1.0	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.3	7.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.3	7.6	GO:0002162	dystroglycan binding(GO:0002162)
0.3	4.5	GO:0004065	arylsulfatase activity(GO:0004065)
0.3	11.5	GO:0015459	potassium channel regulator activity(GO:0015459)
0.3	4.4	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.3	1.6	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056)
0.3	4.7	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.3	4.7	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.3	37.2	GO:0044325	ion channel binding(GO:0044325)
0.3	28.2	GO:0051117	ATPase binding(GO:0051117)
0.3	3.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.3	10.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3	2.4	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.3	14.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.3	4.9	GO:0043295	glutathione binding(GO:0043295)
0.3	4.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.3	13.7	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.3	10.1	GO:0005044	scavenger receptor activity(GO:0005044)
0.3	3.6	GO:0004622	lysophospholipase activity(GO:0004622)
0.2	1.0	GO:0005499	vitamin D binding(GO:0005499)
0.2	58.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	4.3	GO:0005246	calcium channel regulator activity(GO:0005246)
0.2	15.0	GO:0019003	GDP binding(GO:0019003)
0.2	1.3	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.2	15.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2	11.4	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.2	4.8	GO:0003774	motor activity(GO:0003774)
0.2	8.6	GO:0005158	insulin receptor binding(GO:0005158)
0.2	4.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.2	1.2	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.2	13.4	GO:0008013	beta-catenin binding(GO:0008013)
0.2	1.3	GO:0004126	cytidine deaminase activity(GO:0004126)
0.2	4.0	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	1.6	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2	2.6	GO:0004177	aminopeptidase activity(GO:0004177)
0.2	1.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.2	2.4	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.2	34.8	GO:0008022	protein C-terminus binding(GO:0008022)
0.2	9.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2	0.3	GO:0050692	DBD domain binding(GO:0050692)
0.1	3.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1	2.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	3.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	2.3	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.1	7.1	GO:0051219	phosphoprotein binding(GO:0051219)
0.1	2.5	GO:0050811	GABA receptor binding(GO:0050811)
0.1	1.7	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1	0.5	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	1.6	GO:0043495	protein anchor(GO:0043495)
0.1	1.6	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	3.8	GO:0008146	sulfotransferase activity(GO:0008146)
0.1	2.1	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.1	0.9	GO:0019863	IgE binding(GO:0019863)
0.1	0.4	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	4.2	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	0.7	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	10.6	GO:0030246	carbohydrate binding(GO:0030246)
0.1	5.6	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.1	3.3	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1	0.4	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1	2.6	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	1.8	GO:0046961	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.9	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.1	3.5	GO:0043130	ubiquitin binding(GO:0043130)
0.1	0.6	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	4.8	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.1	3.7	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	0.4	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	3.3	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	1.1	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:1903763	gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0	1.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	1.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	1.7	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0	0.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.9	GO:0005507	copper ion binding(GO:0005507)
0.0	2.8	GO:0022857	transmembrane transporter activity(GO:0022857)
0.0	0.6	GO:0003777	microtubule motor activity(GO:0003777)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	96.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.9	110.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
1.5	10.8	PID EPHB FWD PATHWAY	EPHB forward signaling
1.4	26.6	PID ALK2 PATHWAY	ALK2 signaling events
1.1	19.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
1.0	25.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
1.0	17.9	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
1.0	140.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.9	163.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.8	76.6	PID SHP2 PATHWAY	SHP2 signaling
0.8	53.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.8	60.0	PID ENDOTHELIN PATHWAY	Endothelins
0.8	18.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.7	29.9	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.7	35.2	PID BMP PATHWAY	BMP receptor signaling
0.6	18.4	PID RAS PATHWAY	Regulation of Ras family activation
0.6	21.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.6	28.0	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.6	14.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.5	12.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5	24.8	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.5	30.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.4	9.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.4	5.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.3	86.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3	5.8	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.3	10.1	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3	12.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.3	9.0	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.3	7.8	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.3	19.9	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.3	8.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.3	1.8	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.3	12.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.3	9.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2	9.5	PID FGF PATHWAY	FGF signaling pathway
0.2	4.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.2	1.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	4.8	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.2	3.8	ST GA13 PATHWAY	G alpha 13 Pathway
0.2	7.8	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	4.7	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.2	4.1	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.2	4.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.2	4.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	1.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	8.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	6.4	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	3.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	2.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	6.6	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	4.9	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	5.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.1	1.4	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	28.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	4.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	1.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	4.3	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	1.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	2.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	2.0	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	3.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	0.3	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	9.7	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	1.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.7	84.5	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
4.5	107.8	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.9	5.7	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
2.7	34.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
2.6	15.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.5	45.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
2.3	56.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
1.8	23.8	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
1.8	19.7	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.8	3.5	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
1.8	49.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
1.5	43.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.5	21.8	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
1.4	36.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
1.3	25.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
1.3	30.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.3	25.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.2	29.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
1.2	31.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.2	11.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
1.1	9.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.0	17.7	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.9	28.0	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.9	40.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.8	29.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.8	26.0	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.8	29.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.8	15.0	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.8	24.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.8	6.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.8	25.0	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.7	16.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.7	8.0	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.7	31.0	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.7	5.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.7	4.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.7	35.7	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.7	21.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.7	9.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.7	27.2	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.6	24.6	REACTOME AMYLOIDS	Genes involved in Amyloids
0.6	14.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.6	35.2	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.6	20.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.6	17.6	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.6	6.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.6	10.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.6	43.3	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.6	18.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.6	29.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.5	3.8	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.5	97.2	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.5	7.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.5	20.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.5	23.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.5	5.8	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.5	11.4	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.5	18.0	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.5	2.8	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.5	19.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.5	10.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.4	4.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.4	43.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.4	12.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.4	7.0	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.4	8.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.4	10.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.4	10.5	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.4	22.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4	6.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.4	17.5	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.3	11.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	5.8	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.3	12.2	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.3	4.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.3	10.0	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.3	39.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.3	11.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.2	5.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	11.4	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.2	8.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	24.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.2	4.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	2.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.2	13.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2	2.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	5.4	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.2	4.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.2	5.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.2	1.8	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.2	8.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.2	1.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.2	3.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	6.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.2	11.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.2	12.5	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	4.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	5.3	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.1	2.1	REACTOME SIGNALING BY NOTCH1	Genes involved in Signaling by NOTCH1
0.1	1.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	6.8	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1	1.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	0.9	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	1.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.4	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression