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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for ETV2
Z-value: 0.55
Motif logo
Transcription factors associated with ETV2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ETV2
|
ENSG00000105672.10 | ETS variant transcription factor 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETV2 | hg19_v2_chr19_+_36132631_36132695 | -0.06 | 3.4e-01 | Click! |
Activity profile of ETV2 motif
Sorted Z-values of ETV2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ETV2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.9 | 23.7 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 5.2 | 20.9 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
| 5.0 | 19.9 | GO:0090579 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 4.5 | 13.6 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 3.9 | 11.8 | GO:2000097 | chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 3.7 | 14.9 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 3.3 | 16.4 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 3.2 | 9.7 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 3.1 | 12.5 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 2.9 | 8.8 | GO:1900195 | spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195) |
| 2.7 | 8.1 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 2.7 | 13.4 | GO:0002084 | protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 2.7 | 8.0 | GO:0046440 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 2.5 | 7.6 | GO:0051086 | chaperone mediated protein folding independent of cofactor(GO:0051086) |
| 2.2 | 11.1 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 2.2 | 6.5 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
| 1.9 | 15.6 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 1.9 | 7.7 | GO:0001189 | RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189) |
| 1.9 | 7.5 | GO:0006203 | dGTP catabolic process(GO:0006203) |
| 1.9 | 5.6 | GO:1902299 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 1.8 | 7.3 | GO:2000434 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 1.8 | 7.3 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 1.7 | 7.0 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 1.7 | 16.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 1.7 | 1.7 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) |
| 1.6 | 9.7 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 1.6 | 12.7 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 1.5 | 4.6 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 1.5 | 6.0 | GO:1904046 | negative regulation of vascular endothelial growth factor production(GO:1904046) |
| 1.5 | 4.5 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 1.5 | 5.9 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 1.4 | 4.1 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 1.4 | 4.1 | GO:2000276 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) |
| 1.3 | 5.0 | GO:2000645 | negative regulation of receptor catabolic process(GO:2000645) |
| 1.2 | 4.9 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 1.2 | 8.5 | GO:1902915 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 1.2 | 16.8 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 1.2 | 4.8 | GO:0006408 | snRNA export from nucleus(GO:0006408) |
| 1.2 | 4.7 | GO:0090296 | regulation of mitochondrial DNA replication(GO:0090296) |
| 1.2 | 5.8 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 1.2 | 10.4 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 1.2 | 5.8 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 1.1 | 3.4 | GO:1904933 | cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933) |
| 1.1 | 9.0 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 1.1 | 3.3 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 1.1 | 3.3 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 1.1 | 5.5 | GO:0010520 | meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520) |
| 1.1 | 8.8 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 1.1 | 9.5 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 1.0 | 3.1 | GO:0086055 | pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029) |
| 1.0 | 3.1 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 1.0 | 6.2 | GO:0051013 | microtubule severing(GO:0051013) |
| 1.0 | 3.1 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) regulation of viral budding via host ESCRT complex(GO:1903772) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 1.0 | 3.1 | GO:1903722 | regulation of centriole elongation(GO:1903722) |
| 1.0 | 5.0 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 1.0 | 2.9 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 1.0 | 2.9 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 1.0 | 7.7 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 0.9 | 10.1 | GO:0006228 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 0.9 | 27.2 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.9 | 9.8 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.9 | 6.1 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.9 | 66.9 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.8 | 10.2 | GO:0015074 | DNA integration(GO:0015074) |
| 0.8 | 5.9 | GO:1903677 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.8 | 2.5 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
| 0.8 | 2.5 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.8 | 9.1 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.8 | 6.6 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 0.8 | 4.1 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.8 | 2.4 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.8 | 2.4 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 0.8 | 7.9 | GO:0000479 | endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.8 | 2.3 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 0.8 | 5.4 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 0.8 | 6.1 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.8 | 2.3 | GO:0007135 | meiosis II(GO:0007135) |
| 0.7 | 2.2 | GO:1901355 | response to rapamycin(GO:1901355) |
| 0.7 | 7.9 | GO:0006983 | ER overload response(GO:0006983) |
| 0.7 | 2.1 | GO:0006425 | glutaminyl-tRNA aminoacylation(GO:0006425) |
| 0.7 | 6.3 | GO:0071670 | smooth muscle cell chemotaxis(GO:0071670) |
| 0.7 | 5.6 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.7 | 3.5 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 0.7 | 12.4 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.7 | 2.0 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.7 | 29.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.7 | 2.0 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.6 | 9.7 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.6 | 3.8 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.6 | 6.9 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.6 | 3.1 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.6 | 45.0 | GO:0070126 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 0.6 | 2.5 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.6 | 1.2 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 0.6 | 4.9 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.6 | 3.6 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.6 | 3.0 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.6 | 14.9 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
| 0.6 | 5.8 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.6 | 5.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.6 | 8.6 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.6 | 6.2 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.6 | 5.6 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 0.6 | 2.2 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 0.5 | 1.6 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 0.5 | 7.1 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.5 | 7.9 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.5 | 1.0 | GO:0019255 | glucose 1-phosphate metabolic process(GO:0019255) |
| 0.5 | 7.2 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 0.5 | 12.3 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.5 | 20.5 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.5 | 6.1 | GO:0002183 | cytoplasmic translational initiation(GO:0002183) |
| 0.5 | 1.5 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.5 | 5.6 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.5 | 9.0 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.5 | 10.3 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.5 | 1.4 | GO:0010513 | positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.4 | 6.1 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.4 | 1.3 | GO:0009146 | purine nucleoside triphosphate catabolic process(GO:0009146) |
| 0.4 | 2.1 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.4 | 21.7 | GO:0043486 | histone exchange(GO:0043486) |
| 0.4 | 1.3 | GO:0052331 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 0.4 | 3.8 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.4 | 1.2 | GO:0048611 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 0.4 | 4.5 | GO:0002934 | desmosome organization(GO:0002934) |
| 0.4 | 35.7 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.4 | 21.8 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.4 | 1.6 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 0.4 | 4.0 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.4 | 2.0 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.4 | 3.2 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.4 | 1.5 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.4 | 4.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.4 | 1.1 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
| 0.4 | 12.8 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.4 | 2.3 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.4 | 0.7 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.4 | 5.5 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.4 | 4.3 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.4 | 1.1 | GO:0051031 | tRNA transport(GO:0051031) |
| 0.3 | 2.4 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.3 | 2.1 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.3 | 28.1 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.3 | 1.4 | GO:2000317 | negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
| 0.3 | 2.0 | GO:0060701 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of endoribonuclease activity(GO:0060699) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.3 | 1.3 | GO:0090309 | maintenance of DNA methylation(GO:0010216) positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.3 | 3.7 | GO:0035721 | intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.3 | 1.0 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.3 | 32.6 | GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) |
| 0.3 | 2.6 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) |
| 0.3 | 1.3 | GO:0042483 | negative regulation of odontogenesis(GO:0042483) |
| 0.3 | 1.3 | GO:0021539 | subthalamus development(GO:0021539) |
| 0.3 | 38.0 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.3 | 1.9 | GO:0021764 | amygdala development(GO:0021764) |
| 0.3 | 2.6 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.3 | 1.9 | GO:0033504 | floor plate development(GO:0033504) |
| 0.3 | 6.6 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.3 | 2.2 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.3 | 10.4 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.3 | 0.3 | GO:0060086 | circadian temperature homeostasis(GO:0060086) |
| 0.3 | 1.2 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.3 | 6.7 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.3 | 3.9 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 0.3 | 2.7 | GO:0002863 | positive regulation of inflammatory response to antigenic stimulus(GO:0002863) |
| 0.3 | 8.7 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
| 0.3 | 2.7 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.3 | 10.1 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.3 | 1.2 | GO:0061743 | motor learning(GO:0061743) |
| 0.3 | 1.8 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.3 | 1.8 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.3 | 22.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.3 | 4.0 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 0.3 | 1.1 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.3 | 2.5 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.3 | 2.5 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.3 | 0.5 | GO:0090174 | organelle membrane fusion(GO:0090174) |
| 0.3 | 0.5 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 0.3 | 0.5 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.3 | 0.8 | GO:0060406 | regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) |
| 0.2 | 2.0 | GO:0017182 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.2 | 2.9 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.2 | 5.6 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.2 | 1.0 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.2 | 1.4 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.2 | 3.5 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.2 | 2.3 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.2 | 3.9 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.2 | 8.2 | GO:0006482 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) |
| 0.2 | 1.5 | GO:0033523 | histone H2B ubiquitination(GO:0033523) |
| 0.2 | 0.6 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.2 | 8.3 | GO:0042407 | cristae formation(GO:0042407) |
| 0.2 | 1.2 | GO:1902714 | negative regulation of interferon-gamma secretion(GO:1902714) |
| 0.2 | 3.0 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.2 | 5.0 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.2 | 1.0 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.2 | 0.6 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.2 | 5.4 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.2 | 1.3 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.2 | 1.3 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.2 | 1.3 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
| 0.2 | 0.5 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.2 | 2.9 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.2 | 4.1 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.2 | 2.4 | GO:0006289 | nucleotide-excision repair(GO:0006289) |
| 0.2 | 6.9 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.2 | 2.5 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
| 0.2 | 3.8 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.2 | 0.7 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
| 0.2 | 2.8 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.2 | 0.8 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.2 | 1.7 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.2 | 0.9 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.2 | 1.7 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 0.2 | 1.2 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.2 | 2.6 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.2 | 2.2 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.2 | 0.5 | GO:0009452 | 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 0.2 | 2.2 | GO:0002031 | G-protein coupled receptor internalization(GO:0002031) |
| 0.2 | 1.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.2 | 2.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.2 | 2.1 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.1 | 1.3 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.1 | 1.8 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.1 | 1.0 | GO:0001660 | fever generation(GO:0001660) |
| 0.1 | 0.9 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.1 | 1.2 | GO:0023035 | CD40 signaling pathway(GO:0023035) |
| 0.1 | 14.9 | GO:0006413 | translational initiation(GO:0006413) |
| 0.1 | 5.1 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 2.3 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 2.3 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.1 | 1.7 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.1 | 6.5 | GO:1990090 | cellular response to nerve growth factor stimulus(GO:1990090) |
| 0.1 | 0.5 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.1 | 0.7 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) mRNA pseudouridine synthesis(GO:1990481) |
| 0.1 | 2.3 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.1 | 3.5 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.1 | 4.6 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.1 | 2.1 | GO:0010155 | regulation of proton transport(GO:0010155) |
| 0.1 | 0.9 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 0.5 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.1 | 2.6 | GO:0032607 | interferon-alpha production(GO:0032607) |
| 0.1 | 0.6 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.1 | 2.3 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.1 | 1.3 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.1 | 1.4 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.1 | 0.8 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 2.4 | GO:0033962 | cytoplasmic mRNA processing body assembly(GO:0033962) |
| 0.1 | 1.0 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.1 | 0.3 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.1 | 1.8 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.1 | 2.5 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.1 | 4.6 | GO:0050766 | positive regulation of phagocytosis(GO:0050766) |
| 0.1 | 12.8 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.1 | 2.8 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 7.4 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.1 | 0.4 | GO:2000860 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.1 | 1.4 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 1.5 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.1 | 1.2 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 0.1 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
| 0.1 | 2.0 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.1 | 1.5 | GO:0051444 | negative regulation of ubiquitin-protein transferase activity(GO:0051444) |
| 0.1 | 5.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 2.4 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 0.1 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 0.1 | 4.0 | GO:0031529 | ruffle organization(GO:0031529) |
| 0.1 | 0.8 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.1 | 2.1 | GO:0090314 | positive regulation of protein targeting to membrane(GO:0090314) |
| 0.1 | 0.2 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.1 | 0.4 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.1 | 0.2 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 0.1 | 5.5 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.1 | 1.5 | GO:0006378 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 0.1 | 0.4 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.1 | 0.9 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.1 | 0.2 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.1 | 0.2 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
| 0.1 | 0.1 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.1 | 0.2 | GO:0070141 | response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492) |
| 0.1 | 1.7 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.0 | 1.1 | GO:0035825 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
| 0.0 | 1.5 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 0.0 | 8.2 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 0.2 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.0 | 3.2 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.2 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 0.0 | 0.5 | GO:0019934 | cGMP-mediated signaling(GO:0019934) |
| 0.0 | 0.5 | GO:0002467 | germinal center formation(GO:0002467) |
| 0.0 | 3.2 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 2.9 | GO:0008584 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.0 | 0.5 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.2 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.0 | 0.7 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 1.5 | GO:0010596 | negative regulation of endothelial cell migration(GO:0010596) |
| 0.0 | 0.5 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.0 | 0.4 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.0 | 0.7 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.0 | 0.1 | GO:0045054 | constitutive secretory pathway(GO:0045054) |
| 0.0 | 0.8 | GO:0001824 | blastocyst development(GO:0001824) |
| 0.0 | 1.7 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
| 0.0 | 1.2 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 2.8 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 0.8 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 1.7 | GO:0043473 | pigmentation(GO:0043473) |
| 0.0 | 0.3 | GO:0030239 | myofibril assembly(GO:0030239) |
| 0.0 | 0.1 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.0 | 0.1 | GO:0060283 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
| 0.0 | 0.4 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.2 | GO:0051656 | establishment of organelle localization(GO:0051656) |
| 0.0 | 0.1 | GO:0042593 | carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593) |
| 0.0 | 1.6 | GO:0016050 | vesicle organization(GO:0016050) |
| 0.0 | 4.6 | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.0 | 1.0 | GO:0038061 | NIK/NF-kappaB signaling(GO:0038061) |
| 0.0 | 0.3 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 0.6 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
| 0.0 | 0.1 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.9 | 23.7 | GO:0018444 | translation release factor complex(GO:0018444) |
| 5.5 | 16.4 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 3.3 | 26.5 | GO:0005683 | U7 snRNP(GO:0005683) |
| 3.0 | 14.9 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 2.8 | 25.4 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 2.4 | 7.3 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 2.3 | 7.0 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 2.2 | 22.3 | GO:0097255 | R2TP complex(GO:0097255) |
| 2.1 | 19.0 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 2.0 | 8.0 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 1.9 | 23.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 1.9 | 15.3 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 1.9 | 17.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 1.9 | 26.2 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 1.9 | 5.6 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 1.8 | 5.5 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 1.8 | 12.5 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 1.7 | 15.7 | GO:0071439 | clathrin complex(GO:0071439) |
| 1.6 | 1.6 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 1.6 | 19.2 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 1.4 | 15.6 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 1.4 | 4.2 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 1.4 | 5.6 | GO:0045281 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 1.4 | 14.9 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 1.3 | 40.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 1.3 | 7.8 | GO:0071817 | MMXD complex(GO:0071817) |
| 1.2 | 4.8 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 1.2 | 22.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 1.2 | 13.0 | GO:0005688 | U6 snRNP(GO:0005688) |
| 1.2 | 3.5 | GO:0097441 | basilar dendrite(GO:0097441) |
| 1.2 | 7.0 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 1.1 | 8.0 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 1.1 | 6.7 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 1.1 | 5.6 | GO:0032021 | NELF complex(GO:0032021) |
| 1.1 | 10.0 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 1.1 | 3.3 | GO:0034455 | t-UTP complex(GO:0034455) |
| 1.1 | 12.1 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 1.1 | 1.1 | GO:0005687 | U4 snRNP(GO:0005687) |
| 1.0 | 7.2 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 1.0 | 28.8 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 1.0 | 8.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 1.0 | 5.8 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 1.0 | 3.8 | GO:0000811 | GINS complex(GO:0000811) DNA replication preinitiation complex(GO:0031261) |
| 0.9 | 2.8 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.9 | 3.6 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 0.9 | 5.2 | GO:0000796 | condensin complex(GO:0000796) |
| 0.8 | 3.3 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.8 | 5.6 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.8 | 8.7 | GO:0034709 | methylosome(GO:0034709) |