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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ETV7

Z-value: 0.38

Motif logo

Transcription factors associated with ETV7

Gene Symbol Gene ID Gene Info
ENSG00000010030.9 ETS variant transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETV7hg19_v2_chr6_-_36355513_36355578-0.282.6e-05Click!

Activity profile of ETV7 motif

Sorted Z-values of ETV7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_33385854 9.80 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr6_-_33385655 8.79 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr16_+_30078811 8.29 ENST00000564688.1
aldolase A, fructose-bisphosphate
chr6_-_33385870 8.27 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr3_-_131221790 7.91 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr6_-_33385902 7.81 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr15_-_75230368 7.57 ENST00000564811.1
ENST00000562233.1
ENST00000567270.1
ENST00000568783.1
cytochrome c oxidase subunit Va
chr20_-_33872548 7.41 ENST00000374443.3
eukaryotic translation initiation factor 6
chr2_+_201754050 7.35 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr6_-_33385823 7.29 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr15_-_75230478 7.19 ENST00000322347.6
cytochrome c oxidase subunit Va
chr1_+_169079823 7.07 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_+_201754135 6.92 ENST00000409357.1
ENST00000409129.2
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr11_-_65655906 6.76 ENST00000533045.1
ENST00000338369.2
ENST00000357519.4
fibroblast growth factor (acidic) intracellular binding protein
chr20_-_33872518 6.45 ENST00000374436.3
eukaryotic translation initiation factor 6
chr11_-_64084959 6.34 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr1_-_153538292 6.19 ENST00000497140.1
ENST00000368708.3
S100 calcium binding protein A2
chr22_-_36924944 5.98 ENST00000405442.1
ENST00000402116.1
eukaryotic translation initiation factor 3, subunit D
chr19_+_50180317 5.77 ENST00000534465.1
protein arginine methyltransferase 1
chr19_+_19627026 5.76 ENST00000608404.1
ENST00000555938.1
ENST00000503283.1
ENST00000512771.3
ENST00000428459.2
YjeF N-terminal domain containing 3
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr1_-_153538011 5.73 ENST00000368707.4
S100 calcium binding protein A2
chr11_-_64085533 5.58 ENST00000544844.1
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr5_+_271752 5.52 ENST00000505221.1
ENST00000509581.1
ENST00000507528.1
programmed cell death 6
chr5_-_892648 5.50 ENST00000483173.1
ENST00000435709.2
bromodomain containing 9
chr5_+_892745 5.24 ENST00000166345.3
thyroid hormone receptor interactor 13
chr19_-_12792020 5.12 ENST00000594424.1
ENST00000597152.1
ENST00000596162.1
deoxyhypusine synthase
chr8_+_145133493 5.08 ENST00000316052.5
ENST00000525936.1
exosome component 4
chr9_+_131447342 5.07 ENST00000409104.3
SET nuclear oncogene
chr22_-_36925186 4.87 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
eukaryotic translation initiation factor 3, subunit D
chr17_+_49243639 4.86 ENST00000512737.1
ENST00000503064.1
NME1-NME2 readthrough
chr19_+_50180409 4.82 ENST00000391851.4
protein arginine methyltransferase 1
chr8_-_121457332 4.80 ENST00000518918.1
mitochondrial ribosomal protein L13
chr16_-_4401258 4.74 ENST00000577031.1
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr11_-_6502534 4.72 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ADP-ribosylation factor interacting protein 2
chr19_-_12792704 4.66 ENST00000210060.7
deoxyhypusine synthase
chr3_-_195808952 4.60 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
transferrin receptor
chr2_-_234763147 4.57 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
Holliday junction recognition protein
chr16_-_58768177 4.57 ENST00000434819.2
ENST00000245206.5
glutamic-oxaloacetic transaminase 2, mitochondrial
chr17_+_49243792 4.53 ENST00000393183.3
ENST00000393190.1
NME1-NME2 readthrough
chr19_+_19626531 4.49 ENST00000507754.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr11_+_64008443 4.42 ENST00000309366.4
FK506 binding protein 2, 13kDa
chr19_-_12792585 4.40 ENST00000351660.5
deoxyhypusine synthase
chr20_+_55926583 4.40 ENST00000395840.2
ribonucleic acid export 1
chr3_-_195808980 4.36 ENST00000360110.4
transferrin receptor
chr21_-_33985127 4.34 ENST00000290155.3
chromosome 21 open reading frame 59
chr3_+_184033135 4.19 ENST00000424196.1
eukaryotic translation initiation factor 4 gamma, 1
chr12_+_52626898 4.19 ENST00000331817.5
keratin 7
chr16_-_66968055 4.18 ENST00000568572.1
family with sequence similarity 96, member B
chr19_-_3061397 4.11 ENST00000586839.1
amino-terminal enhancer of split
chr6_+_111195973 4.09 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
adenosylmethionine decarboxylase 1
chr16_-_4401284 4.08 ENST00000318059.3
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr5_+_271733 4.06 ENST00000264933.4
programmed cell death 6
chr16_-_66968265 4.05 ENST00000567511.1
ENST00000422424.2
family with sequence similarity 96, member B
chr20_+_55926274 4.01 ENST00000371242.2
ENST00000527947.1
ribonucleic acid export 1
chr12_-_6960407 4.01 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
cell division cycle associated 3
chr20_+_1099233 3.91 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr12_+_16035307 3.90 ENST00000538352.1
ENST00000025399.6
ENST00000419869.2
serine/threonine kinase receptor associated protein
chr19_-_10230540 3.90 ENST00000589454.1
eukaryotic translation initiation factor 3, subunit G
chr22_-_42086477 3.88 ENST00000402458.1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr5_-_150466692 3.84 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNFAIP3 interacting protein 1
chr2_+_234621551 3.83 ENST00000608381.1
ENST00000373414.3
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr1_-_169337176 3.82 ENST00000472647.1
ENST00000367811.3
NME/NM23 family member 7
chr11_-_6502580 3.78 ENST00000423813.2
ENST00000396777.3
ADP-ribosylation factor interacting protein 2
chr12_+_20968608 3.77 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr2_+_234637754 3.76 ENST00000482026.1
ENST00000609767.1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr14_-_67878917 3.75 ENST00000216446.4
pleckstrin 2
chr22_-_36877371 3.71 ENST00000403313.1
thioredoxin 2
chr4_-_106629796 3.70 ENST00000416543.1
ENST00000515819.1
ENST00000420368.2
ENST00000503746.1
ENST00000340139.5
ENST00000433009.1
integrator complex subunit 12
chr7_-_100895414 3.70 ENST00000435848.1
ENST00000474120.1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr12_-_112856623 3.67 ENST00000551291.2
ribosomal protein L6
chr19_-_50370799 3.64 ENST00000600910.1
ENST00000322344.3
ENST00000600573.1
polynucleotide kinase 3'-phosphatase
chr10_+_94352956 3.64 ENST00000260731.3
kinesin family member 11
chr19_+_36236514 3.62 ENST00000222266.2
presenilin enhancer gamma secretase subunit
chr14_-_23504337 3.62 ENST00000361611.6
proteasome (prosome, macropain) subunit, beta type, 5
chr11_+_64008525 3.62 ENST00000449942.2
FK506 binding protein 2, 13kDa
chr19_+_35739897 3.57 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
lipolysis stimulated lipoprotein receptor
chr7_+_856246 3.57 ENST00000389574.3
ENST00000457378.2
ENST00000452783.2
ENST00000435699.1
ENST00000440380.1
ENST00000439679.1
ENST00000424128.1
Sad1 and UNC84 domain containing 1
chr19_-_10230562 3.56 ENST00000587146.1
ENST00000588709.1
ENST00000253108.4
eukaryotic translation initiation factor 3, subunit G
chr7_-_7680601 3.55 ENST00000396682.2
replication protein A3, 14kDa
chr14_-_23504432 3.51 ENST00000425762.2
proteasome (prosome, macropain) subunit, beta type, 5
chr8_-_121457608 3.51 ENST00000306185.3
mitochondrial ribosomal protein L13
chr2_-_73964447 3.47 ENST00000272424.5
ENST00000409716.2
ENST00000318190.7
TP53RK binding protein
chr19_+_35739782 3.44 ENST00000347609.4
lipolysis stimulated lipoprotein receptor
chr15_-_101835110 3.43 ENST00000560496.1
small nuclear ribonucleoprotein polypeptide A'
chr4_+_17812525 3.39 ENST00000251496.2
non-SMC condensin I complex, subunit G
chr19_+_36236491 3.39 ENST00000591949.1
presenilin enhancer gamma secretase subunit
chr12_+_32832134 3.37 ENST00000452533.2
dynamin 1-like
chr13_-_113862948 3.35 ENST00000375457.2
ENST00000375477.1
ENST00000246505.5
ENST00000337344.4
ENST00000375479.2
PCI domain containing 2
chr3_-_11610255 3.34 ENST00000424529.2
vestigial like 4 (Drosophila)
chr12_+_32832203 3.32 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
dynamin 1-like
chr20_-_2644832 3.31 ENST00000380851.5
ENST00000380843.4
isocitrate dehydrogenase 3 (NAD+) beta
chr16_-_69373396 3.30 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
component of oligomeric golgi complex 8
chr1_-_27216729 3.27 ENST00000431781.2
ENST00000374135.4
GPN-loop GTPase 2
chr2_-_106013400 3.26 ENST00000409807.1
four and a half LIM domains 2
chr2_-_170681324 3.25 ENST00000409340.1
methyltransferase like 5
chr17_-_7218631 3.23 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
G protein pathway suppressor 2
chr20_-_2451395 3.21 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
small nuclear ribonucleoprotein polypeptides B and B1
chr7_+_2281843 3.20 ENST00000356714.1
ENST00000397049.1
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr11_+_110300607 3.19 ENST00000260270.2
ferredoxin 1
chr5_+_10353780 3.19 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chrX_+_21958674 3.19 ENST00000404933.2
spermine synthase
chr14_-_23504087 3.19 ENST00000493471.2
ENST00000460922.2
proteasome (prosome, macropain) subunit, beta type, 5
chr1_+_27648648 3.18 ENST00000374076.4
transmembrane protein 222
chr10_+_75504105 3.14 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24 family member C
chr1_+_27648709 3.10 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
transmembrane protein 222
chr1_-_45988542 3.08 ENST00000424390.1
peroxiredoxin 1
chr18_+_72167096 3.07 ENST00000324301.8
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr11_-_9336234 3.04 ENST00000528080.1
transmembrane protein 41B
chr1_+_64058939 3.04 ENST00000371084.3
phosphoglucomutase 1
chr6_+_149721495 3.03 ENST00000326669.4
small ubiquitin-like modifier 4
chr1_-_33283754 3.03 ENST00000373477.4
tyrosyl-tRNA synthetase
chr15_-_101835414 3.01 ENST00000254193.6
small nuclear ribonucleoprotein polypeptide A'
chr7_-_100888337 3.01 ENST00000223136.4
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr3_+_149191723 3.00 ENST00000305354.4
transmembrane 4 L six family member 4
chr16_-_67493110 2.98 ENST00000602876.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr13_+_48611665 2.97 ENST00000258662.2
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr17_-_80231557 2.97 ENST00000392334.2
ENST00000314028.6
casein kinase 1, delta
chr7_-_100888313 2.93 ENST00000442303.1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr11_+_121447469 2.92 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr8_+_86089460 2.91 ENST00000418930.2
E2F transcription factor 5, p130-binding
chr19_+_41256764 2.86 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
small nuclear ribonucleoprotein polypeptide A
chr19_-_291365 2.85 ENST00000591572.1
ENST00000269812.3
ENST00000434325.2
phosphatidic acid phosphatase type 2C
chr12_+_123464607 2.85 ENST00000543566.1
ENST00000315580.5
ENST00000542099.1
ENST00000392435.2
ENST00000413381.2
ENST00000426960.2
ENST00000453766.2
ADP-ribosylation-like factor 6 interacting protein 4
chr19_+_17862274 2.84 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCH domain only 1
chr11_+_118889456 2.82 ENST00000528230.1
ENST00000525303.1
ENST00000434101.2
ENST00000359005.4
ENST00000533058.1
trafficking protein particle complex 4
chr2_+_39005336 2.82 ENST00000409566.1
gem (nuclear organelle) associated protein 6
chr11_-_122930121 2.82 ENST00000524552.1
heat shock 70kDa protein 8
chrX_+_21958814 2.81 ENST00000379404.1
ENST00000415881.2
spermine synthase
chr22_+_32340481 2.81 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr14_-_58894223 2.81 ENST00000555593.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr1_+_8021713 2.77 ENST00000338639.5
ENST00000493678.1
ENST00000377493.5
parkinson protein 7
chr17_-_27916555 2.77 ENST00000394869.3
G protein-coupled receptor kinase interacting ArfGAP 1
chr2_+_39005325 2.76 ENST00000281950.3
gem (nuclear organelle) associated protein 6
chr1_+_32687971 2.76 ENST00000373586.1
eukaryotic translation initiation factor 3, subunit I
chr19_-_40971643 2.75 ENST00000595483.1
biliverdin reductase B (flavin reductase (NADPH))
chr6_-_170862322 2.74 ENST00000262193.6
proteasome (prosome, macropain) subunit, beta type, 1
chr11_+_118889142 2.71 ENST00000533632.1
trafficking protein particle complex 4
chr16_+_69373323 2.70 ENST00000254940.5
NIP7, nucleolar pre-rRNA processing protein
chr7_+_100860949 2.70 ENST00000305105.2
zinc finger, HIT-type containing 1
chr5_-_140027357 2.70 ENST00000252102.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr1_-_38061522 2.62 ENST00000373062.3
guanine nucleotide binding protein-like 2 (nucleolar)
chr14_-_23904861 2.60 ENST00000355349.3
myosin, heavy chain 7, cardiac muscle, beta
chr1_-_235292250 2.60 ENST00000366607.4
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr16_-_28222797 2.59 ENST00000569951.1
ENST00000565698.1
exportin 6
chr6_+_47445467 2.55 ENST00000359314.5
CD2-associated protein
chr11_-_71823796 2.55 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
anaphase promoting complex subunit 15
chr21_-_33984865 2.54 ENST00000458138.1
chromosome 21 open reading frame 59
chr12_+_69080734 2.54 ENST00000378905.2
nucleoporin 107kDa
chr11_+_65337901 2.53 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
Sjogren syndrome/scleroderma autoantigen 1
chr10_+_105036909 2.53 ENST00000369849.4
internexin neuronal intermediate filament protein, alpha
chr13_+_34392185 2.50 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr4_-_183838372 2.49 ENST00000503820.1
ENST00000503988.1
dCMP deaminase
chr19_-_40971667 2.49 ENST00000263368.4
biliverdin reductase B (flavin reductase (NADPH))
chr3_-_130465604 2.46 ENST00000356763.3
phosphoinositide-3-kinase, regulatory subunit 4
chr14_-_58893832 2.44 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr2_-_122407097 2.43 ENST00000409078.3
cytoplasmic linker associated protein 1
chr17_+_7155819 2.42 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr5_-_140070897 2.42 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
histidyl-tRNA synthetase
chr9_+_131084815 2.42 ENST00000300452.3
ENST00000609948.1
coenzyme Q4
chr10_-_104192405 2.40 ENST00000369937.4
CUE domain containing 2
chr20_+_47835884 2.39 ENST00000371764.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr7_+_5085452 2.36 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr11_-_134093827 2.35 ENST00000534548.2
non-SMC condensin II complex, subunit D3
chr6_-_160210604 2.35 ENST00000420894.2
ENST00000539756.1
ENST00000544255.1
t-complex 1
chr16_-_30204987 2.34 ENST00000569282.1
ENST00000567436.1
bolA family member 2B
chr3_+_160117087 2.34 ENST00000357388.3
structural maintenance of chromosomes 4
chr11_-_57298187 2.34 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr9_-_113018746 2.32 ENST00000374515.5
thioredoxin
chr5_+_96079240 2.32 ENST00000515663.1
calpastatin
chr20_-_36661826 2.31 ENST00000373448.2
ENST00000373447.3
TELO2 interacting protein 1
chrX_+_11129388 2.30 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr12_+_109535923 2.30 ENST00000336865.2
uracil-DNA glycosylase
chr17_+_7155556 2.29 ENST00000570500.1
ENST00000574993.1
ENST00000396628.2
ENST00000573657.1
elongator acetyltransferase complex subunit 5
chr11_+_46369077 2.28 ENST00000456247.2
ENST00000421244.2
ENST00000318201.8
diacylglycerol kinase, zeta
chrX_-_80457385 2.27 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
high mobility group nucleosome binding domain 5
chr6_-_31620403 2.26 ENST00000451898.1
ENST00000439687.2
ENST00000362049.6
ENST00000424480.1
BCL2-associated athanogene 6
chr11_-_59578202 2.25 ENST00000300151.4
mitochondrial ribosomal protein L16
chr11_-_71823715 2.24 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr6_+_150070831 2.23 ENST00000367380.5
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr11_+_46368975 2.20 ENST00000527911.1
diacylglycerol kinase, zeta
chr9_-_127952032 2.18 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
protein phosphatase 6, catalytic subunit
chr11_+_46368956 2.17 ENST00000543978.1
diacylglycerol kinase, zeta
chr11_-_62476965 2.15 ENST00000405837.1
ENST00000531524.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_+_69373661 2.13 ENST00000254941.6
NIP7, nucleolar pre-rRNA processing protein
chr2_-_74607390 2.13 ENST00000413111.1
ENST00000409567.3
ENST00000454119.1
ENST00000361874.3
ENST00000394003.3
dynactin 1
chr1_+_8021954 2.12 ENST00000377491.1
ENST00000377488.1
parkinson protein 7
chr2_+_10442993 2.12 ENST00000423674.1
ENST00000307845.3
hippocalcin-like 1
chr3_-_197282821 2.09 ENST00000445160.2
ENST00000446746.1
ENST00000432819.1
ENST00000392379.1
ENST00000441275.1
ENST00000392378.2
3-hydroxybutyrate dehydrogenase, type 1
chr13_+_113633620 2.03 ENST00000421756.1
ENST00000375601.3
MCF.2 cell line derived transforming sequence-like
chr17_+_80009741 2.02 ENST00000578552.1
ENST00000320548.4
ENST00000581578.1
ENST00000583885.1
ENST00000583641.1
ENST00000581418.1
ENST00000355130.2
ENST00000306823.6
ENST00000392358.2
G protein pathway suppressor 1
chr4_-_860950 2.00 ENST00000511980.1
ENST00000510799.1
cyclin G associated kinase
chr11_+_75110530 2.00 ENST00000531188.1
ENST00000530164.1
ENST00000422465.2
ENST00000278572.6
ENST00000534440.1
ENST00000527446.1
ENST00000526608.1
ENST00000527273.1
ENST00000524851.1
ribosomal protein S3
chr16_-_12009833 1.99 ENST00000420576.2
G1 to S phase transition 1
chr17_-_5322786 1.95 ENST00000225696.4
nucleoporin 88kDa
chr6_-_34855773 1.94 ENST00000420584.2
ENST00000361288.4
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
chr3_+_142720366 1.92 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2 snRNP-associated SURP domain containing
chr11_+_66824276 1.92 ENST00000308831.2
ras homolog family member D
chr19_+_1440838 1.91 ENST00000594262.1
Uncharacterized protein
chr20_-_34542548 1.91 ENST00000305978.2
SCAN domain containing 1
chr3_+_179322573 1.90 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 15.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
3.6 10.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
3.4 10.1 GO:0006597 spermine biosynthetic process(GO:0006597)
3.3 16.3 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
3.0 11.9 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
2.8 14.2 GO:0046203 spermidine catabolic process(GO:0046203)
2.1 19.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.8 7.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
1.8 10.6 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.7 5.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
1.6 4.9 GO:0018307 peptidyl-cysteine oxidation(GO:0018171) enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
1.5 6.2 GO:0006203 dGTP catabolic process(GO:0006203)
1.5 4.6 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) L-kynurenine metabolic process(GO:0097052)
1.5 7.6 GO:0070980 biphenyl catabolic process(GO:0070980)
1.5 7.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
1.5 14.9 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
1.4 7.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.4 9.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
1.3 3.8 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.1 3.3 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
1.0 4.1 GO:1904379 maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
1.0 1.0 GO:0090149 mitochondrial membrane fission(GO:0090149)
1.0 3.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
1.0 3.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.0 2.9 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.0 4.9 GO:0098502 DNA dephosphorylation(GO:0098502)
0.9 3.5 GO:0034398 telomere tethering at nuclear periphery(GO:0034398)
0.8 2.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.8 9.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.8 3.1 GO:0016074 snoRNA metabolic process(GO:0016074)
0.8 11.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.7 5.2 GO:0007144 female meiosis I(GO:0007144)
0.7 4.5 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.7 14.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.7 2.0 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.7 3.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.7 2.6 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.6 1.8 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.6 2.5 GO:0030242 pexophagy(GO:0030242)
0.6 4.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.6 4.1 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.6 2.8 GO:0072318 clathrin coat disassembly(GO:0072318)
0.5 5.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.5 5.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.5 4.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.5 2.5 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 2.0 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.5 3.5 GO:0006116 NADH oxidation(GO:0006116)
0.5 3.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.5 3.4 GO:0030091 protein repair(GO:0030091)
0.5 2.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.5 10.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.5 3.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.5 9.0 GO:0097286 iron ion import(GO:0097286)
0.5 4.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.5 8.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5 1.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 0.4 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.4 1.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.4 1.3 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.4 4.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.4 2.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.4 1.3 GO:0033341 regulation of collagen binding(GO:0033341)
0.4 0.8 GO:0018344 protein prenylation(GO:0018342) protein geranylgeranylation(GO:0018344) prenylation(GO:0097354)
0.4 1.2 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.4 1.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 1.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 0.7 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.4 1.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.4 3.3 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.3 3.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.3 3.8 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.3 3.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 5.4 GO:0007220 Notch receptor processing(GO:0007220) membrane protein intracellular domain proteolysis(GO:0031293)
0.3 4.8 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.3 1.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 3.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.3 2.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.3 5.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.3 12.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 2.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 18.5 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 4.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 5.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 3.8 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 5.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 3.0 GO:0019388 galactose catabolic process(GO:0019388)
0.2 1.4 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.1 GO:0021553 olfactory nerve development(GO:0021553)
0.2 0.9 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 0.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 0.6 GO:0016095 polyprenol catabolic process(GO:0016095)
0.2 1.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2 1.7 GO:0046618 drug export(GO:0046618)
0.2 4.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.2 1.8 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.2 1.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 0.6 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.2 5.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 1.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 0.6 GO:0008050 female courtship behavior(GO:0008050)
0.2 1.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.2 1.7 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.2 3.5 GO:0051014 actin filament severing(GO:0051014)
0.2 4.6 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 3.2 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 1.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.2 8.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 18.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.2 0.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.2 1.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 3.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.2 2.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2 0.7 GO:0050684 regulation of mRNA processing(GO:0050684)
0.2 3.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 12.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 7.7 GO:0043486 histone exchange(GO:0043486)
0.2 0.5 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.2 0.8 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 2.8 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 2.5 GO:0016180 snRNA processing(GO:0016180)
0.1 1.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.6 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) negative regulation of natural killer cell activation(GO:0032815) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.1 1.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.9 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.8 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 2.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 2.9 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 1.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 7.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.9 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 2.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 3.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 3.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.7 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 1.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.3 GO:0010041 response to iron(III) ion(GO:0010041) dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.1 8.1 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 3.5 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 3.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 2.2 GO:0042255 ribosome assembly(GO:0042255)
0.1 2.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.5 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 2.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 0.3 GO:0030047 actin modification(GO:0030047)
0.1 0.8 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.2 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.4 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.5 GO:0051036 regulation of endosome size(GO:0051036)
0.1 0.6 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.2 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 2.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 3.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 4.4 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 1.0 GO:0031297 replication fork processing(GO:0031297)
0.1 0.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.7 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.1 25.8 GO:0010038 response to metal ion(GO:0010038)
0.1 3.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 1.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 2.0 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.1 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 4.6 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 1.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.6 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 1.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.7 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 1.1 GO:0060065 uterus development(GO:0060065)
0.0 1.6 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.3 GO:0072319 vesicle uncoating(GO:0072319)
0.0 0.8 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 2.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.6 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 1.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.1 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 2.3 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 3.7 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.7 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.0 1.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.9 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.3 GO:0006414 translational elongation(GO:0006414)
0.0 1.4 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 1.1 GO:0021766 hippocampus development(GO:0021766)
0.0 4.3 GO:0030030 cell projection organization(GO:0030030)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.9 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.0 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.4 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.0 0.5 GO:0022900 electron transport chain(GO:0022900)
0.0 3.6 GO:0006413 translational initiation(GO:0006413)
0.0 0.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.1 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 1.5 GO:0015918 sterol transport(GO:0015918)
0.0 1.4 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.1 GO:0010629 negative regulation of gene expression(GO:0010629)
0.0 2.5 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 1.2 GO:0050871 positive regulation of B cell activation(GO:0050871)
0.0 0.2 GO:0043065 positive regulation of apoptotic process(GO:0043065)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.7 15.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.6 6.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
1.4 8.2 GO:0071817 MMXD complex(GO:0071817)
1.2 7.0 GO:0061689 tricellular tight junction(GO:0061689)
1.1 14.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.0 4.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.0 13.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
1.0 3.0 GO:0018444 translation release factor complex(GO:0018444)
0.9 9.5 GO:0032797 SMN complex(GO:0032797)
0.8 2.5 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.8 13.1 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.8 8.1 GO:0000796 condensin complex(GO:0000796)
0.8 13.8 GO:0034709 methylosome(GO:0034709)
0.7 4.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.7 2.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.6 8.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.6 7.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.6 14.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.6 3.0 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.6 18.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.6 1.7 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.6 2.8 GO:0071986 Ragulator complex(GO:0071986)
0.5 3.2 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.5 4.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.5 7.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.5 3.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.5 2.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.5 7.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.5 5.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.4 5.4 GO:0030008 TRAPP complex(GO:0030008)
0.4 6.6 GO:0005686 U2 snRNP(GO:0005686)
0.4 1.3 GO:1902636 kinociliary basal body(GO:1902636)
0.4 12.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 17.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 2.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.4 2.8 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.4 7.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 1.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.4 3.5 GO:0032039 integrator complex(GO:0032039)
0.4 2.9 GO:0031931 TORC1 complex(GO:0031931)
0.4 7.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 22.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 1.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 4.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 0.9 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.3 5.1 GO:0005839 proteasome core complex(GO:0005839)
0.3 1.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 0.8 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 1.4 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.3 3.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 3.8 GO:0017119 Golgi transport complex(GO:0017119)
0.3 1.6 GO:1902560 GMP reductase complex(GO:1902560)
0.2 12.9 GO:0031430 M band(GO:0031430)
0.2 3.1 GO:0042555 MCM complex(GO:0042555)
0.2 3.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 3.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 3.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 0.8 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 3.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 4.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.5 GO:0005883 neurofilament(GO:0005883)
0.2 2.9 GO:0005685 U1 snRNP(GO:0005685)
0.2 3.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 2.6 GO:0032982 myosin filament(GO:0032982)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 2.1 GO:0005869 dynactin complex(GO:0005869)
0.1 4.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.7 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 3.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.7 GO:0071010 prespliceosome(GO:0071010)
0.1 2.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 6.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.3 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.1 0.4 GO:0032044 DSIF complex(GO:0032044)
0.1 1.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 8.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 2.0 GO:0098576 lumenal side of membrane(GO:0098576)
0.1 7.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 3.8 GO:0045095 keratin filament(GO:0045095)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 3.6 GO:0030027 lamellipodium(GO:0030027)
0.1 8.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.5 GO:0031105 septin complex(GO:0031105)
0.1 5.0 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 0.8 GO:0031906 late endosome lumen(GO:0031906)
0.1 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.4 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 4.5 GO:0005811 lipid particle(GO:0005811)
0.1 3.5 GO:0043195 terminal bouton(GO:0043195)
0.1 2.5 GO:0031941 filamentous actin(GO:0031941)
0.1 0.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 2.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.2 GO:0015030 Cajal body(GO:0015030)
0.0 7.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.1 GO:0014704 intercalated disc(GO:0014704)
0.0 2.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 3.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 1.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.2 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.5 GO:0031904 endosome lumen(GO:0031904)
0.0 1.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 2.7 GO:0005819 spindle(GO:0005819)
0.0 1.4 GO:0005903 brush border(GO:0005903)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.2 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
3.0 12.2 GO:0004998 transferrin receptor activity(GO:0004998)
2.8 13.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
2.1 6.2 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
1.8 10.6 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
1.5 4.6 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.3 5.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.3 5.2 GO:0004074 biliverdin reductase activity(GO:0004074)
1.2 4.9 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
1.2 4.9 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
1.2 3.5 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.1 3.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.0 3.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
1.0 4.1 GO:0043515 kinetochore binding(GO:0043515)
1.0 4.1 GO:0004132 dCMP deaminase activity(GO:0004132)
1.0 9.7 GO:0030620 U2 snRNA binding(GO:0030620)
0.8 3.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.8 8.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.7 2.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.7 13.1 GO:0043495 protein anchor(GO:0043495)
0.6 3.0 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.6 42.6 GO:0005507 copper ion binding(GO:0005507)
0.5 3.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.5 3.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.5 3.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.5 1.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.5 3.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.5 10.8 GO:0000339 RNA cap binding(GO:0000339)
0.5 3.8 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.5 14.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 7.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.4 7.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 1.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.4 3.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.4 1.3 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.4 8.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.4 4.8 GO:0031386 protein tag(GO:0031386)
0.4 2.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4 1.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.4 3.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 10.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 6.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 2.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 17.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 1.7 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.3 2.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3 4.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 1.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 1.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 8.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 0.8 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.3 1.3 GO:0002046 opsin binding(GO:0002046)
0.3 1.6 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3 2.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 0.7 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 0.5 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2 3.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 5.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 3.9 GO:0070628 proteasome binding(GO:0070628)
0.2 6.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 12.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 4.3 GO:0051400 BH domain binding(GO:0051400)
0.2 3.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 7.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 3.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 3.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 2.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 1.5 GO:0004064 arylesterase activity(GO:0004064)
0.2 3.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 0.9 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 3.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 2.0 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 0.6 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.2 0.6 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 1.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 0.8 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.2 GO:0019863 IgE binding(GO:0019863)
0.1 0.9 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 4.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 1.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.6 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 5.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 3.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 2.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 11.1 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 2.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 11.0 GO:0051087 chaperone binding(GO:0051087)
0.1 3.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 6.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 22.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 3.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 3.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.8 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 4.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 4.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.5 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 1.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 5.0 GO:0031491 nucleosome binding(GO:0031491)
0.1 6.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 3.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.4 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 1.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.6 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 2.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.8 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 1.4 GO:0046961 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 4.1 GO:0043130 ubiquitin binding(GO:0043130)
0.1 2.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 2.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 1.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 1.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.7 GO:0050699 WW domain binding(GO:0050699)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 3.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 3.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 1.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 9.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 4.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 2.0 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 1.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 7.0 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.8 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.5 PID ARF 3PATHWAY Arf1 pathway
0.2 4.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 3.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 10.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 12.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 11.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 5.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.6 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 4.8 PID AURORA B PATHWAY Aurora B signaling
0.1 4.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.0 PID ATR PATHWAY ATR signaling pathway
0.1 1.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 8.2 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 0.8 PID MYC PATHWAY C-MYC pathway
0.1 3.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 0.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 4.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 5.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 2.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.5 12.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.5 7.0 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.4 4.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.4 13.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.4 10.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.4 13.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 31.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.4 6.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.4 21.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.4 13.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.3 0.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.3 8.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.3 10.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 25.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.3 16.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 19.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 3.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 3.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 7.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 7.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 5.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 4.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 3.6 REACTOME KINESINS Genes involved in Kinesins
0.1 3.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 3.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 12.0 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1 3.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 3.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 8.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 8.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 4.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.7 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.0 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 4.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 1.7 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.9 REACTOME TRANSLATION Genes involved in Translation
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 1.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases