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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for FIGLA

Z-value: 0.78

Motif logo

Transcription factors associated with FIGLA

Gene Symbol Gene ID Gene Info
ENSG00000183733.6 folliculogenesis specific bHLH transcription factor

Activity profile of FIGLA motif

Sorted Z-values of FIGLA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_12727250 26.17 ENST00000404894.1
ADP-ribosylation factor-like 4A
chr17_-_79805146 22.62 ENST00000415593.1
prolyl 4-hydroxylase, beta polypeptide
chr1_+_22328144 20.77 ENST00000290122.3
ENST00000374663.1
chymotrypsin-like elastase family, member 3A
chr3_-_49066811 20.74 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr1_-_150669500 20.16 ENST00000271732.3
golgi phosphoprotein 3-like
chr20_+_44441304 18.68 ENST00000352551.5
ubiquitin-conjugating enzyme E2C
chr20_+_44441215 18.56 ENST00000356455.4
ENST00000405520.1
ubiquitin-conjugating enzyme E2C
chr17_+_76164639 18.02 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
synaptogyrin 2
chr13_+_28194873 17.93 ENST00000302979.3
polymerase (RNA) I polypeptide D, 16kDa
chr7_-_99698338 17.25 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr11_+_118958689 17.14 ENST00000535253.1
ENST00000392841.1
hydroxymethylbilane synthase
chr17_+_76165213 15.78 ENST00000590201.1
synaptogyrin 2
chr16_-_12009833 15.45 ENST00000420576.2
G1 to S phase transition 1
chr6_+_34204642 15.37 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr6_+_22569784 14.59 ENST00000510882.2
hepatoma derived growth factor-like 1
chr19_+_16186903 14.50 ENST00000588507.1
tropomyosin 4
chr4_-_103749179 14.16 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr6_-_31697255 14.08 ENST00000436437.1
dimethylarginine dimethylaminohydrolase 2
chr5_-_150466692 13.87 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNFAIP3 interacting protein 1
chr7_+_130020180 13.23 ENST00000481342.1
ENST00000011292.3
ENST00000604896.1
carboxypeptidase A1 (pancreatic)
chr4_-_103749205 13.05 ENST00000508249.1
ubiquitin-conjugating enzyme E2D 3
chr7_-_150675372 12.56 ENST00000262186.5
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr12_+_48357340 12.40 ENST00000256686.6
ENST00000549288.1
ENST00000552561.1
ENST00000546749.1
ENST00000552546.1
ENST00000550552.1
transmembrane protein 106C
chr11_-_88070920 12.20 ENST00000524463.1
ENST00000227266.5
cathepsin C
chr12_+_48357401 11.54 ENST00000429772.2
ENST00000449758.2
transmembrane protein 106C
chr3_+_49059038 11.51 ENST00000451378.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr8_-_103668114 11.37 ENST00000285407.6
Kruppel-like factor 10
chr4_-_140223670 11.34 ENST00000394228.1
ENST00000539387.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr3_+_148545586 11.28 ENST00000282957.4
ENST00000468341.1
carboxypeptidase B1 (tissue)
chr6_-_42016385 11.28 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
cyclin D3
chr1_-_167905225 11.19 ENST00000367846.4
mitochondrial pyruvate carrier 2
chr4_-_140223614 10.96 ENST00000394223.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr12_-_49333446 10.65 ENST00000537495.1
Uncharacterized protein
chr17_+_39240459 10.49 ENST00000391417.4
keratin associated protein 4-7
chr6_-_31697563 10.32 ENST00000375789.2
ENST00000416410.1
dimethylarginine dimethylaminohydrolase 2
chr3_+_172468472 10.29 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr11_+_86511569 9.64 ENST00000441050.1
protease, serine, 23
chr15_+_89182178 9.53 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chrX_-_16887963 9.47 ENST00000380084.4
retinoblastoma binding protein 7
chr19_+_50180317 9.35 ENST00000534465.1
protein arginine methyltransferase 1
chr1_+_22303503 9.25 ENST00000337107.6
chymotrypsin-like elastase family, member 3B
chr19_-_10230540 9.23 ENST00000589454.1
eukaryotic translation initiation factor 3, subunit G
chr5_+_34656569 9.05 ENST00000428746.2
retinoic acid induced 14
chr5_+_52856456 8.99 ENST00000296684.5
ENST00000506765.1
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr14_+_35452104 8.88 ENST00000216774.6
ENST00000546080.1
signal recognition particle 54kDa
chr2_-_163008903 8.88 ENST00000418842.2
ENST00000375497.3
glucagon
chr8_-_49834299 8.78 ENST00000396822.1
snail family zinc finger 2
chr7_-_148725733 8.76 ENST00000286091.4
protein disulfide isomerase family A, member 4
chr8_-_117768023 8.74 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
eukaryotic translation initiation factor 3, subunit H
chr19_+_35739631 8.71 ENST00000602003.1
ENST00000360798.3
ENST00000354900.3
lipolysis stimulated lipoprotein receptor
chr15_+_89181974 8.57 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr17_+_45286387 8.54 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
myosin, light chain 4, alkali; atrial, embryonic
chr5_+_122110691 8.52 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chr14_-_55369525 8.50 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GTP cyclohydrolase 1
chr17_+_48133459 8.46 ENST00000320031.8
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr19_+_16187085 8.42 ENST00000300933.4
tropomyosin 4
chrX_-_153775426 8.20 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr7_-_140179276 8.18 ENST00000443720.2
ENST00000255977.2
makorin ring finger protein 1
chr8_-_102216925 8.18 ENST00000517844.1
zinc finger protein 706
chr16_-_103572 8.06 ENST00000293860.5
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr6_-_35888824 8.01 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr19_+_35739597 8.00 ENST00000361790.3
lipolysis stimulated lipoprotein receptor
chrX_-_134049262 7.98 ENST00000370783.3
motile sperm domain containing 1
chr19_-_10230562 7.93 ENST00000587146.1
ENST00000588709.1
ENST00000253108.4
eukaryotic translation initiation factor 3, subunit G
chr14_+_35452169 7.89 ENST00000555557.1
signal recognition particle 54kDa
chr19_+_35739280 7.84 ENST00000602122.1
lipolysis stimulated lipoprotein receptor
chr1_-_11120057 7.73 ENST00000376957.2
spermidine synthase
chr6_-_31550192 7.54 ENST00000429299.2
ENST00000446745.2
lymphotoxin beta (TNF superfamily, member 3)
chr1_+_45478568 7.53 ENST00000428106.1
uroporphyrinogen decarboxylase
chr9_+_133710453 7.35 ENST00000318560.5
c-abl oncogene 1, non-receptor tyrosine kinase
chr17_+_73521763 7.33 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
lethal giant larvae homolog 2 (Drosophila)
chr8_-_49833978 7.23 ENST00000020945.1
snail family zinc finger 2
chr13_-_41635512 7.07 ENST00000405737.2
E74-like factor 1 (ets domain transcription factor)
chr2_-_220436248 6.92 ENST00000265318.4
obscurin-like 1
chr6_+_7107999 6.71 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr17_-_7165662 6.71 ENST00000571881.2
ENST00000360325.7
claudin 7
chr11_-_118972575 6.65 ENST00000432443.2
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr6_-_35888905 6.64 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr9_+_33795533 6.63 ENST00000379405.3
protease, serine, 3
chr13_+_26828275 6.44 ENST00000381527.3
cyclin-dependent kinase 8
chr19_+_35739782 6.37 ENST00000347609.4
lipolysis stimulated lipoprotein receptor
chr17_+_39411636 6.36 ENST00000394008.1
keratin associated protein 9-9
chr1_-_201391149 6.35 ENST00000555948.1
ENST00000556362.1
troponin I type 1 (skeletal, slow)
chr13_-_113862948 6.32 ENST00000375457.2
ENST00000375477.1
ENST00000246505.5
ENST00000337344.4
ENST00000375479.2
PCI domain containing 2
chr16_-_2314222 6.22 ENST00000566397.1
RNA binding protein S1, serine-rich domain
chr3_-_46904946 6.19 ENST00000292327.4
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_+_22307592 6.09 ENST00000400277.2
chymotrypsin-like elastase family, member 3B
chr6_+_33172407 6.03 ENST00000374662.3
hydroxysteroid (17-beta) dehydrogenase 8
chr9_+_135937365 6.03 ENST00000372080.4
ENST00000351304.7
carboxyl ester lipase
chr2_-_152590946 5.99 ENST00000172853.10
nebulin
chr7_+_130794846 5.97 ENST00000421797.2
muskelin 1, intracellular mediator containing kelch motifs
chr3_-_46904918 5.95 ENST00000395869.1
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr6_-_10419871 5.87 ENST00000319516.4
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr16_-_12009735 5.80 ENST00000439887.2
ENST00000434724.2
G1 to S phase transition 1
chr11_-_2182388 5.79 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
insulin
INS-IGF2 readthrough
chr1_-_160990886 5.73 ENST00000537746.1
F11 receptor
chr2_+_170590321 5.72 ENST00000392647.2
kelch-like family member 23
chr8_+_145438870 5.65 ENST00000527931.1
family with sequence similarity 203, member B
chr14_-_106586656 5.48 ENST00000390602.2
immunoglobulin heavy variable 3-13
chr12_-_13248732 5.47 ENST00000396302.3
germ cell associated 1
chr11_+_69455855 5.43 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr1_+_104293028 5.42 ENST00000370079.3
amylase, alpha 1C (salivary)
chr3_+_52454971 5.40 ENST00000465863.1
PHD finger protein 7
chr16_-_11375179 5.36 ENST00000312511.3
protamine 1
chr11_+_60223312 5.35 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
membrane-spanning 4-domains, subfamily A, member 1
chr11_+_71249071 5.32 ENST00000398534.3
keratin associated protein 5-8
chr19_+_50936142 5.31 ENST00000357701.5
myosin binding protein C, fast type
chr4_-_186456652 5.31 ENST00000284767.5
ENST00000284770.5
PDZ and LIM domain 3
chr11_+_60223225 5.28 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chr3_-_167191814 5.22 ENST00000466903.1
ENST00000264677.4
serpin peptidase inhibitor, clade I (pancpin), member 2
chr1_-_40367668 5.11 ENST00000397332.2
ENST00000429311.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr18_+_48405419 5.09 ENST00000321341.5
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr12_-_13248705 5.06 ENST00000396310.2
germ cell associated 1
chr4_-_186456766 5.04 ENST00000284771.6
PDZ and LIM domain 3
chr4_-_103748880 4.96 ENST00000453744.2
ENST00000349311.8
ubiquitin-conjugating enzyme E2D 3
chr18_+_48405463 4.92 ENST00000382927.3
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr6_-_114292449 4.85 ENST00000519065.1
histone deacetylase 2
chr2_-_179672142 4.84 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
titin
chr20_+_44044717 4.78 ENST00000279036.6
ENST00000279035.9
ENST00000372689.5
ENST00000545755.1
ENST00000341555.5
ENST00000535404.1
ENST00000543458.2
ENST00000432270.1
phosphatidylinositol glycan anchor biosynthesis, class T
chr17_-_39191107 4.76 ENST00000344363.5
keratin associated protein 1-3
chr4_-_151936865 4.74 ENST00000535741.1
LPS-responsive vesicle trafficking, beach and anchor containing
chrX_-_153714994 4.73 ENST00000369660.4
ubiquitin-like 4A
chr8_-_80993010 4.69 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr16_+_32077386 4.65 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr8_-_103424986 4.62 ENST00000521922.1
ubiquitin protein ligase E3 component n-recognin 5
chr12_-_13248562 4.59 ENST00000457134.2
ENST00000537302.1
germ cell associated 1
chr4_-_76598544 4.53 ENST00000515457.1
ENST00000357854.3
GTPase activating protein (SH3 domain) binding protein 2
chr2_+_37571717 4.51 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chr4_-_103749105 4.49 ENST00000394801.4
ENST00000394804.2
ubiquitin-conjugating enzyme E2D 3
chr8_-_103424916 4.46 ENST00000220959.4
ubiquitin protein ligase E3 component n-recognin 5
chr4_-_103749313 4.46 ENST00000394803.5
ubiquitin-conjugating enzyme E2D 3
chr7_+_128470431 4.30 ENST00000325888.8
ENST00000346177.6
filamin C, gamma
chr5_-_140053152 4.29 ENST00000542735.1
DND microRNA-mediated repression inhibitor 1
chr5_-_54281407 4.22 ENST00000381403.4
endothelial cell-specific molecule 1
chr5_-_54281491 4.18 ENST00000381405.4
endothelial cell-specific molecule 1
chrX_-_118827333 4.18 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
septin 6
chr16_+_30383613 4.12 ENST00000568749.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr22_+_38245414 4.12 ENST00000381683.6
ENST00000414316.1
ENST00000406934.1
ENST00000451427.1
eukaryotic translation initiation factor 3, subunit L
chr5_+_68788594 4.10 ENST00000396442.2
ENST00000380766.2
occludin
chr8_-_145018905 4.05 ENST00000398774.2
plectin
chr2_+_37571845 4.05 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chr3_-_50360192 4.04 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
hyaluronoglucosaminidase 2
chr16_-_30006922 3.98 ENST00000564026.1
HIRA interacting protein 3
chr1_-_42384343 3.97 ENST00000372584.1
human immunodeficiency virus type I enhancer binding protein 3
chrX_-_11445856 3.97 ENST00000380736.1
Rho GTPase activating protein 6
chr16_+_67233412 3.96 ENST00000477898.1
engulfment and cell motility 3
chr3_-_49722523 3.89 ENST00000448220.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr10_-_30638090 3.89 ENST00000421701.1
ENST00000263063.4
mitochondrial poly(A) polymerase
chr22_+_22988816 3.82 ENST00000480559.1
ENST00000448514.1
gamma-glutamyltransferase light chain 2
chr1_-_39339777 3.80 ENST00000397572.2
MYC binding protein
chr14_-_90085458 3.79 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
forkhead box N3
chr6_-_31938700 3.69 ENST00000495340.1
decapping exoribonuclease
chr22_-_37882395 3.60 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_-_175113088 3.56 ENST00000409546.1
ENST00000428402.2
Obg-like ATPase 1
chr15_+_89182156 3.51 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr1_+_26737253 3.49 ENST00000326279.6
lin-28 homolog A (C. elegans)
chr5_+_34656331 3.36 ENST00000265109.3
retinoic acid induced 14
chr17_+_40985407 3.36 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr8_-_99837856 3.35 ENST00000518165.1
ENST00000419617.2
serine/threonine kinase 3
chr2_+_220436917 3.34 ENST00000243786.2
inhibin, alpha
chr1_-_27216729 3.33 ENST00000431781.2
ENST00000374135.4
GPN-loop GTPase 2
chr11_-_122931881 3.24 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chr11_+_128634589 3.22 ENST00000281428.8
Fli-1 proto-oncogene, ETS transcription factor
chr12_-_53994805 3.12 ENST00000328463.7
activating transcription factor 7
chr13_+_115000339 3.08 ENST00000360383.3
ENST00000375312.3
cell division cycle 16
chr14_-_50999307 3.01 ENST00000013125.4
mitogen-activated protein kinase kinase kinase kinase 5
chr1_+_168250194 3.00 ENST00000367821.3
T-box 19
chr7_+_93535817 2.99 ENST00000248572.5
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr1_-_154842741 2.93 ENST00000271915.4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr12_+_19282643 2.92 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
pleckstrin homology domain containing, family A member 5
chr17_-_46035187 2.91 ENST00000300557.2
proline rich 15-like
chr2_-_152590982 2.89 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
nebulin
chr11_-_19223523 2.89 ENST00000265968.3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr14_-_37051798 2.88 ENST00000258829.5
NK2 homeobox 8
chr20_-_22566089 2.85 ENST00000377115.4
forkhead box A2
chr11_+_7618413 2.82 ENST00000528883.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr13_+_112721913 2.81 ENST00000330949.1
SRY (sex determining region Y)-box 1
chr14_+_67707826 2.79 ENST00000261681.4
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr1_-_46152174 2.77 ENST00000290795.3
ENST00000355105.3
GC-rich promoter binding protein 1-like 1
chr1_+_150954493 2.76 ENST00000368947.4
annexin A9
chr3_+_182511266 2.73 ENST00000323116.5
ENST00000493826.1
ATPase, class VI, type 11B
chr1_-_171621815 2.73 ENST00000037502.6
myocilin, trabecular meshwork inducible glucocorticoid response
chr8_-_81083731 2.64 ENST00000379096.5
tumor protein D52
chr7_-_11871815 2.61 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr4_+_169418195 2.58 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr6_+_46761118 2.55 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr14_-_107131560 2.50 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr10_-_33625154 2.46 ENST00000265371.4
neuropilin 1
chr17_-_39538550 2.45 ENST00000394001.1
keratin 34
chr7_+_77428066 2.44 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
putative homeodomain transcription factor 2
chr4_-_139163491 2.37 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_-_111991850 2.35 ENST00000411751.2
WD repeat domain 77
chr19_-_42916499 2.30 ENST00000601189.1
ENST00000599211.1
lipase, hormone-sensitive
chr11_-_117698787 2.30 ENST00000260287.2
FXYD domain containing ion transport regulator 2
chr1_-_156675535 2.29 ENST00000368221.1
cellular retinoic acid binding protein 2
chr19_-_39881777 2.15 ENST00000595564.1
ENST00000221265.3
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr16_+_103816 2.14 ENST00000383018.3
ENST00000417493.1
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr17_-_56429500 2.03 ENST00000225504.3
suppressor of Ty 4 homolog 1 (S. cerevisiae)
chr8_-_103425047 2.03 ENST00000520539.1
ubiquitin protein ligase E3 component n-recognin 5
chr3_-_49851313 1.98 ENST00000333486.3
ubiquitin-like modifier activating enzyme 7

Network of associatons between targets according to the STRING database.

First level regulatory network of FIGLA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
7.1 21.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
6.2 30.9 GO:1904274 tricellular tight junction assembly(GO:1904274)
5.6 16.8 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
5.3 16.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
4.7 37.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536)
4.6 13.9 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
4.2 12.6 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
3.8 15.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
3.5 20.7 GO:0006177 GMP biosynthetic process(GO:0006177)
3.0 8.9 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
2.9 8.6 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
2.8 8.5 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
2.8 22.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
2.8 11.2 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.7 8.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
2.7 21.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
2.4 7.3 GO:0001922 B-1 B cell homeostasis(GO:0001922)
2.2 8.9 GO:0007525 somatic muscle development(GO:0007525)
1.9 7.7 GO:0035995 detection of muscle stretch(GO:0035995)
1.9 5.8 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
1.9 17.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.9 24.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
1.6 11.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
1.6 9.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.5 24.4 GO:0006527 arginine catabolic process(GO:0006527)
1.5 6.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
1.5 5.9 GO:0003409 optic cup structural organization(GO:0003409)
1.5 14.6 GO:0035092 sperm chromatin condensation(GO:0035092)
1.4 10.0 GO:1902031 regulation of NADP metabolic process(GO:1902031)
1.3 6.7 GO:0019348 dolichol metabolic process(GO:0019348)
1.3 6.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.2 8.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
1.2 7.0 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
1.1 45.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
1.1 3.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
1.1 7.7 GO:0008295 spermidine biosynthetic process(GO:0008295)
1.0 5.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.0 12.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.0 4.0 GO:0019087 transformation of host cell by virus(GO:0019087)
1.0 4.8 GO:0006344 maintenance of chromatin silencing(GO:0006344) fungiform papilla formation(GO:0061198)
0.9 2.8 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.9 7.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.9 2.7 GO:0097254 renal tubular secretion(GO:0097254)
0.8 3.3 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.8 8.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.8 4.7 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.7 3.5 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.7 3.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.7 10.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.7 4.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.7 2.7 GO:0015917 aminophospholipid transport(GO:0015917)
0.7 2.7 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.7 20.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.6 3.2 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.6 26.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.6 8.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.5 6.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.5 1.5 GO:0072312 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.5 2.5 GO:1905040 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.5 2.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.5 34.7 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.5 6.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.4 4.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.4 2.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.4 6.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 2.8 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 4.3 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.4 1.2 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.4 23.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.4 2.1 GO:0016584 nucleosome positioning(GO:0016584)
0.4 19.3 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3 8.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.3 1.0 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3 5.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.3 9.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3 3.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 1.8 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.3 4.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.3 11.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.3 12.2 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.3 10.3 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.3 3.9 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.3 4.1 GO:0070673 response to interleukin-18(GO:0070673)
0.3 3.8 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 6.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3 3.7 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.3 6.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 2.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 2.0 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.2 0.7 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 6.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 5.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.7 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2 3.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 0.7 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.2 1.3 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.2 2.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 0.9 GO:0060023 soft palate development(GO:0060023)
0.2 1.5 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.2 27.7 GO:0031424 keratinization(GO:0031424)
0.2 1.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.2 6.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.2 1.8 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.2 4.0 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.2 29.7 GO:0008203 cholesterol metabolic process(GO:0008203)
0.2 3.2 GO:0035855 megakaryocyte development(GO:0035855)
0.2 2.0 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 5.4 GO:0030261 chromosome condensation(GO:0030261)
0.2 5.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 0.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 2.7 GO:0003334 keratinocyte development(GO:0003334)
0.2 2.0 GO:0051775 response to redox state(GO:0051775)
0.1 2.8 GO:0008105 asymmetric protein localization(GO:0008105)
0.1 0.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 1.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 3.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 10.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 8.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 10.6 GO:0042100 B cell proliferation(GO:0042100)
0.1 4.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.7 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.5 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.1 1.2 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.9 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.1 3.0 GO:0048747 muscle fiber development(GO:0048747)
0.1 3.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.4 GO:0032423 regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
0.1 1.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 3.0 GO:0021983 pituitary gland development(GO:0021983)
0.1 1.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 8.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 1.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 2.4 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 6.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.7 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1 6.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.9 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 3.8 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.9 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 1.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 6.9 GO:0002576 platelet degranulation(GO:0002576)
0.0 3.6 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.7 GO:0048536 spleen development(GO:0048536)
0.0 4.0 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 2.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.6 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.6 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 1.9 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 2.6 GO:0007586 digestion(GO:0007586)
0.0 7.8 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 3.4 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 2.5 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 1.6 GO:0042742 defense response to bacterium(GO:0042742)
0.0 2.9 GO:0061458 reproductive system development(GO:0061458)
0.0 3.1 GO:0043687 post-translational protein modification(GO:0043687)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
7.1 21.3 GO:0018444 translation release factor complex(GO:0018444)
5.2 30.9 GO:0061689 tricellular tight junction(GO:0061689)
2.8 8.5 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
2.5 12.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
2.3 6.9 GO:1990393 3M complex(GO:1990393)
2.1 16.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
2.1 10.3 GO:0097149 centralspindlin complex(GO:0097149)
1.6 4.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
1.4 8.5 GO:0030905 retromer, tubulation complex(GO:0030905)
1.4 42.0 GO:0005680 anaphase-promoting complex(GO:0005680)
1.4 15.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.3 17.2 GO:0042555 MCM complex(GO:0042555)
1.2 22.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.2 30.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
1.2 4.7 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.1 3.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
1.0 26.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.8 26.4 GO:0005859 muscle myosin complex(GO:0005859)
0.7 5.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.7 12.9 GO:0034709 methylosome(GO:0034709)
0.7 6.2 GO:0061574 ASAP complex(GO:0061574)
0.6 27.2 GO:0045095 keratin filament(GO:0045095)
0.6 3.4 GO:0008537 proteasome activator complex(GO:0008537)
0.6 14.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 1.5 GO:0005607 laminin-2 complex(GO:0005607)
0.5 1.5 GO:0005608 laminin-3 complex(GO:0005608)
0.5 2.0 GO:0032044 DSIF complex(GO:0032044)
0.5 2.8 GO:0043219 lateral loop(GO:0043219)
0.5 3.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.4 11.2 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.4 2.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.4 1.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.4 10.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 4.2 GO:0097227 sperm annulus(GO:0097227)
0.3 27.0 GO:0031594 neuromuscular junction(GO:0031594)
0.3 6.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 16.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 6.3 GO:0005861 troponin complex(GO:0005861)
0.3 21.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3 16.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 4.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 2.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 16.0 GO:0015030 Cajal body(GO:0015030)
0.2 2.5 GO:0002116 semaphorin receptor complex(GO:0002116) sorting endosome(GO:0097443)
0.2 18.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 4.1 GO:0030056 hemidesmosome(GO:0030056)
0.2 2.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 15.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 8.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 2.7 GO:0033268 node of Ranvier(GO:0033268)
0.2 0.5 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 2.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 3.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 5.4 GO:0000786 nucleosome(GO:0000786)
0.1 3.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 1.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 8.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 13.3 GO:0001650 fibrillar center(GO:0001650)
0.1 12.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.1 GO:0097440 apical dendrite(GO:0097440)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.1 0.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 3.1 GO:0034399 nuclear periphery(GO:0034399)
0.1 37.5 GO:0010008 endosome membrane(GO:0010008)
0.1 8.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 5.0 GO:0005901 caveola(GO:0005901)
0.1 7.5 GO:0005884 actin filament(GO:0005884)
0.1 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.1 3.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 79.2 GO:0005615 extracellular space(GO:0005615)
0.1 2.3 GO:0031672 A band(GO:0031672)
0.1 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 30.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 13.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.9 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 12.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.8 GO:0030018 Z disc(GO:0030018)
0.0 13.8 GO:0005815 microtubule organizing center(GO:0005815)
0.0 3.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.4 GO:0001726 ruffle(GO:0001726)
0.0 2.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.5 GO:0016607 nuclear speck(GO:0016607)
0.0 11.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.6 GO:0008859 exoribonuclease II activity(GO:0008859)
5.2 20.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
5.2 20.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
4.9 24.4 GO:0016403 dimethylargininase activity(GO:0016403)
4.5 22.6 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
3.5 21.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
3.4 16.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
2.9 8.6 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
2.8 8.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
2.7 8.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
2.6 7.7 GO:0004766 spermidine synthase activity(GO:0004766)
2.5 7.5 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
2.4 7.3 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
2.2 6.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
2.1 12.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.7 8.5 GO:1990460 leptin receptor binding(GO:1990460)
1.7 78.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.7 10.0 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
1.6 4.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
1.6 9.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
1.4 8.5 GO:0019238 cyclohydrolase activity(GO:0019238)
1.4 11.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.3 3.9 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
1.2 3.7 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
1.2 6.0 GO:0070404 NADH binding(GO:0070404)
1.2 6.0 GO:0004771 sterol esterase activity(GO:0004771)
1.1 26.0 GO:0001056 RNA polymerase III activity(GO:0001056)
1.0 4.0 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.9 15.4 GO:0003906 AT DNA binding(GO:0003680) DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.9 3.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 19.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.8 24.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.8 2.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.7 11.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.7 10.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.6 2.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.6 49.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 3.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.5 13.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.5 8.6 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.5 2.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.5 12.2 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.4 11.2 GO:0001968 fibronectin binding(GO:0001968)
0.4 23.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.4 7.8 GO:0035198 miRNA binding(GO:0035198)
0.4 3.3 GO:0034711 inhibin binding(GO:0034711)
0.4 30.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.4 7.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.4 16.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.4 22.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.4 3.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.3 14.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 2.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 20.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 1.8 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.3 1.5 GO:0050436 microfibril binding(GO:0050436)
0.3 1.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.3 1.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 2.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 3.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 2.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 3.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 9.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.2 1.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 63.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 4.3 GO:0030506 ankyrin binding(GO:0030506)
0.2 6.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 17.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.2 0.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 8.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 3.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 5.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 7.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 5.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 24.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.2 GO:0016918 retinal binding(GO:0016918)
0.1 1.5 GO:0030955 potassium ion binding(GO:0030955)
0.1 3.0 GO:0003924 GTPase activity(GO:0003924)
0.1 1.2 GO:0070888 E-box binding(GO:0070888)
0.1 2.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 11.1 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.6 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.7 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 11.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 6.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 6.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 19.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 5.8 GO:0005179 hormone activity(GO:0005179)
0.0 21.1 GO:0005525 GTP binding(GO:0005525)
0.0 1.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 4.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.9 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0033612 receptor serine/threonine kinase binding(GO:0033612) transmembrane receptor protein serine/threonine kinase binding(GO:0070696) BMP receptor binding(GO:0070700)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0015485 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.0 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 41.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.3 18.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 5.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 69.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 10.6 PID IL23 PATHWAY IL23-mediated signaling events
0.2 15.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 17.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 14.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 2.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 10.3 PID PLK1 PATHWAY PLK1 signaling events
0.2 7.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 8.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 5.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 3.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 3.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 3.0 PID TNF PATHWAY TNF receptor signaling pathway
0.1 5.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 4.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 3.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 3.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 2.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 4.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 15.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.5 42.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
1.2 20.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.1 26.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
1.1 17.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.1 38.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.0 22.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.9 24.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.9 60.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.9 14.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.5 5.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 15.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 8.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 25.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 7.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 23.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 17.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 10.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 5.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 6.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 21.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 3.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 19.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 10.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 4.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 4.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 4.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 6.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 4.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 4.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 9.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 7.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 6.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 4.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 16.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 3.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 2.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 4.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 12.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 3.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 10.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 8.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport