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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for FIGLA
Z-value: 0.78
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Transcription factors associated with FIGLA
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
FIGLA
|
ENSG00000183733.6 | folliculogenesis specific bHLH transcription factor |
Activity profile of FIGLA motif
Sorted Z-values of FIGLA motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_12727250 | 26.17 |
ENST00000404894.1
|
ARL4A
|
ADP-ribosylation factor-like 4A |
| chr17_-_79805146 | 22.62 |
ENST00000415593.1
|
P4HB
|
prolyl 4-hydroxylase, beta polypeptide |
| chr1_+_22328144 | 20.77 |
ENST00000290122.3
ENST00000374663.1 |
CELA3A
|
chymotrypsin-like elastase family, member 3A |
| chr3_-_49066811 | 20.74 |
ENST00000442157.1
ENST00000326739.4 |
IMPDH2
|
IMP (inosine 5'-monophosphate) dehydrogenase 2 |
| chr1_-_150669500 | 20.16 |
ENST00000271732.3
|
GOLPH3L
|
golgi phosphoprotein 3-like |
| chr20_+_44441304 | 18.68 |
ENST00000352551.5
|
UBE2C
|
ubiquitin-conjugating enzyme E2C |
| chr20_+_44441215 | 18.56 |
ENST00000356455.4
ENST00000405520.1 |
UBE2C
|
ubiquitin-conjugating enzyme E2C |
| chr17_+_76164639 | 18.02 |
ENST00000225777.3
ENST00000585591.1 ENST00000589711.1 ENST00000588282.1 ENST00000589168.1 |
SYNGR2
|
synaptogyrin 2 |
| chr13_+_28194873 | 17.93 |
ENST00000302979.3
|
POLR1D
|
polymerase (RNA) I polypeptide D, 16kDa |
| chr7_-_99698338 | 17.25 |
ENST00000354230.3
ENST00000425308.1 |
MCM7
|
minichromosome maintenance complex component 7 |
| chr11_+_118958689 | 17.14 |
ENST00000535253.1
ENST00000392841.1 |
HMBS
|
hydroxymethylbilane synthase |
| chr17_+_76165213 | 15.78 |
ENST00000590201.1
|
SYNGR2
|
synaptogyrin 2 |
| chr16_-_12009833 | 15.45 |
ENST00000420576.2
|
GSPT1
|
G1 to S phase transition 1 |
| chr6_+_34204642 | 15.37 |
ENST00000347617.6
ENST00000401473.3 ENST00000311487.5 ENST00000447654.1 ENST00000395004.3 |
HMGA1
|
high mobility group AT-hook 1 |
| chr6_+_22569784 | 14.59 |
ENST00000510882.2
|
HDGFL1
|
hepatoma derived growth factor-like 1 |
| chr19_+_16186903 | 14.50 |
ENST00000588507.1
|
TPM4
|
tropomyosin 4 |
| chr4_-_103749179 | 14.16 |
ENST00000502690.1
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr6_-_31697255 | 14.08 |
ENST00000436437.1
|
DDAH2
|
dimethylarginine dimethylaminohydrolase 2 |
| chr5_-_150466692 | 13.87 |
ENST00000315050.7
ENST00000523338.1 ENST00000522100.1 |
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr7_+_130020180 | 13.23 |
ENST00000481342.1
ENST00000011292.3 ENST00000604896.1 |
CPA1
|
carboxypeptidase A1 (pancreatic) |
| chr4_-_103749205 | 13.05 |
ENST00000508249.1
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr7_-_150675372 | 12.56 |
ENST00000262186.5
|
KCNH2
|
potassium voltage-gated channel, subfamily H (eag-related), member 2 |
| chr12_+_48357340 | 12.40 |
ENST00000256686.6
ENST00000549288.1 ENST00000552561.1 ENST00000546749.1 ENST00000552546.1 ENST00000550552.1 |
TMEM106C
|
transmembrane protein 106C |
| chr11_-_88070920 | 12.20 |
ENST00000524463.1
ENST00000227266.5 |
CTSC
|
cathepsin C |
| chr12_+_48357401 | 11.54 |
ENST00000429772.2
ENST00000449758.2 |
TMEM106C
|
transmembrane protein 106C |
| chr3_+_49059038 | 11.51 |
ENST00000451378.2
|
NDUFAF3
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 |
| chr8_-_103668114 | 11.37 |
ENST00000285407.6
|
KLF10
|
Kruppel-like factor 10 |
| chr4_-_140223670 | 11.34 |
ENST00000394228.1
ENST00000539387.1 |
NDUFC1
|
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa |
| chr3_+_148545586 | 11.28 |
ENST00000282957.4
ENST00000468341.1 |
CPB1
|
carboxypeptidase B1 (tissue) |
| chr6_-_42016385 | 11.28 |
ENST00000502771.1
ENST00000508143.1 ENST00000514588.1 ENST00000510503.1 ENST00000415497.2 ENST00000372988.4 |
CCND3
|
cyclin D3 |
| chr1_-_167905225 | 11.19 |
ENST00000367846.4
|
MPC2
|
mitochondrial pyruvate carrier 2 |
| chr4_-_140223614 | 10.96 |
ENST00000394223.1
|
NDUFC1
|
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa |
| chr12_-_49333446 | 10.65 |
ENST00000537495.1
|
AC073610.5
|
Uncharacterized protein |
| chr17_+_39240459 | 10.49 |
ENST00000391417.4
|
KRTAP4-7
|
keratin associated protein 4-7 |
| chr6_-_31697563 | 10.32 |
ENST00000375789.2
ENST00000416410.1 |
DDAH2
|
dimethylarginine dimethylaminohydrolase 2 |
| chr3_+_172468472 | 10.29 |
ENST00000232458.5
ENST00000392692.3 |
ECT2
|
epithelial cell transforming sequence 2 oncogene |
| chr11_+_86511569 | 9.64 |
ENST00000441050.1
|
PRSS23
|
protease, serine, 23 |
| chr15_+_89182178 | 9.53 |
ENST00000559876.1
|
ISG20
|
interferon stimulated exonuclease gene 20kDa |
| chrX_-_16887963 | 9.47 |
ENST00000380084.4
|
RBBP7
|
retinoblastoma binding protein 7 |
| chr19_+_50180317 | 9.35 |
ENST00000534465.1
|
PRMT1
|
protein arginine methyltransferase 1 |
| chr1_+_22303503 | 9.25 |
ENST00000337107.6
|
CELA3B
|
chymotrypsin-like elastase family, member 3B |
| chr19_-_10230540 | 9.23 |
ENST00000589454.1
|
EIF3G
|
eukaryotic translation initiation factor 3, subunit G |
| chr5_+_34656569 | 9.05 |
ENST00000428746.2
|
RAI14
|
retinoic acid induced 14 |
| chr5_+_52856456 | 8.99 |
ENST00000296684.5
ENST00000506765.1 |
NDUFS4
|
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) |
| chr14_+_35452104 | 8.88 |
ENST00000216774.6
ENST00000546080.1 |
SRP54
|
signal recognition particle 54kDa |
| chr2_-_163008903 | 8.88 |
ENST00000418842.2
ENST00000375497.3 |
GCG
|
glucagon |
| chr8_-_49834299 | 8.78 |
ENST00000396822.1
|
SNAI2
|
snail family zinc finger 2 |
| chr7_-_148725733 | 8.76 |
ENST00000286091.4
|
PDIA4
|
protein disulfide isomerase family A, member 4 |
| chr8_-_117768023 | 8.74 |
ENST00000518949.1
ENST00000522453.1 ENST00000521861.1 ENST00000518995.1 |
EIF3H
|
eukaryotic translation initiation factor 3, subunit H |
| chr19_+_35739631 | 8.71 |
ENST00000602003.1
ENST00000360798.3 ENST00000354900.3 |
LSR
|
lipolysis stimulated lipoprotein receptor |
| chr15_+_89181974 | 8.57 |
ENST00000306072.5
|
ISG20
|
interferon stimulated exonuclease gene 20kDa |
| chr17_+_45286387 | 8.54 |
ENST00000572316.1
ENST00000354968.1 ENST00000576874.1 ENST00000536623.2 |
MYL4
|
myosin, light chain 4, alkali; atrial, embryonic |
| chr5_+_122110691 | 8.52 |
ENST00000379516.2
ENST00000505934.1 ENST00000514949.1 |
SNX2
|
sorting nexin 2 |
| chr14_-_55369525 | 8.50 |
ENST00000543643.2
ENST00000536224.2 ENST00000395514.1 ENST00000491895.2 |
GCH1
|
GTP cyclohydrolase 1 |
| chr17_+_48133459 | 8.46 |
ENST00000320031.8
|
ITGA3
|
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| chr19_+_16187085 | 8.42 |
ENST00000300933.4
|
TPM4
|
tropomyosin 4 |
| chrX_-_153775426 | 8.20 |
ENST00000393562.2
|
G6PD
|
glucose-6-phosphate dehydrogenase |
| chr7_-_140179276 | 8.18 |
ENST00000443720.2
ENST00000255977.2 |
MKRN1
|
makorin ring finger protein 1 |
| chr8_-_102216925 | 8.18 |
ENST00000517844.1
|
ZNF706
|
zinc finger protein 706 |
| chr16_-_103572 | 8.06 |
ENST00000293860.5
|
POLR3K
|
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| chr6_-_35888824 | 8.01 |
ENST00000361690.3
ENST00000512445.1 |
SRPK1
|
SRSF protein kinase 1 |
| chr19_+_35739597 | 8.00 |
ENST00000361790.3
|
LSR
|
lipolysis stimulated lipoprotein receptor |
| chrX_-_134049262 | 7.98 |
ENST00000370783.3
|
MOSPD1
|
motile sperm domain containing 1 |
| chr19_-_10230562 | 7.93 |
ENST00000587146.1
ENST00000588709.1 ENST00000253108.4 |
EIF3G
|
eukaryotic translation initiation factor 3, subunit G |
| chr14_+_35452169 | 7.89 |
ENST00000555557.1
|
SRP54
|
signal recognition particle 54kDa |
| chr19_+_35739280 | 7.84 |
ENST00000602122.1
|
LSR
|
lipolysis stimulated lipoprotein receptor |
| chr1_-_11120057 | 7.73 |
ENST00000376957.2
|
SRM
|
spermidine synthase |
| chr6_-_31550192 | 7.54 |
ENST00000429299.2
ENST00000446745.2 |
LTB
|
lymphotoxin beta (TNF superfamily, member 3) |
| chr1_+_45478568 | 7.53 |
ENST00000428106.1
|
UROD
|
uroporphyrinogen decarboxylase |
| chr9_+_133710453 | 7.35 |
ENST00000318560.5
|
ABL1
|
c-abl oncogene 1, non-receptor tyrosine kinase |
| chr17_+_73521763 | 7.33 |
ENST00000167462.5
ENST00000375227.4 ENST00000392550.3 ENST00000578363.1 ENST00000579392.1 |
LLGL2
|
lethal giant larvae homolog 2 (Drosophila) |
| chr8_-_49833978 | 7.23 |
ENST00000020945.1
|
SNAI2
|
snail family zinc finger 2 |
| chr13_-_41635512 | 7.07 |
ENST00000405737.2
|
ELF1
|
E74-like factor 1 (ets domain transcription factor) |
| chr2_-_220436248 | 6.92 |
ENST00000265318.4
|
OBSL1
|
obscurin-like 1 |
| chr6_+_7107999 | 6.71 |
ENST00000491191.1
ENST00000379938.2 ENST00000471433.1 |
RREB1
|
ras responsive element binding protein 1 |
| chr17_-_7165662 | 6.71 |
ENST00000571881.2
ENST00000360325.7 |
CLDN7
|
claudin 7 |
| chr11_-_118972575 | 6.65 |
ENST00000432443.2
|
DPAGT1
|
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) |
| chr6_-_35888905 | 6.64 |
ENST00000510290.1
ENST00000423325.2 ENST00000373822.1 |
SRPK1
|
SRSF protein kinase 1 |
| chr9_+_33795533 | 6.63 |
ENST00000379405.3
|
PRSS3
|
protease, serine, 3 |
| chr13_+_26828275 | 6.44 |
ENST00000381527.3
|
CDK8
|
cyclin-dependent kinase 8 |
| chr19_+_35739782 | 6.37 |
ENST00000347609.4
|
LSR
|
lipolysis stimulated lipoprotein receptor |
| chr17_+_39411636 | 6.36 |
ENST00000394008.1
|
KRTAP9-9
|
keratin associated protein 9-9 |
| chr1_-_201391149 | 6.35 |
ENST00000555948.1
ENST00000556362.1 |
TNNI1
|
troponin I type 1 (skeletal, slow) |
| chr13_-_113862948 | 6.32 |
ENST00000375457.2
ENST00000375477.1 ENST00000246505.5 ENST00000337344.4 ENST00000375479.2 |
PCID2
|
PCI domain containing 2 |
| chr16_-_2314222 | 6.22 |
ENST00000566397.1
|
RNPS1
|
RNA binding protein S1, serine-rich domain |
| chr3_-_46904946 | 6.19 |
ENST00000292327.4
|
MYL3
|
myosin, light chain 3, alkali; ventricular, skeletal, slow |
| chr1_+_22307592 | 6.09 |
ENST00000400277.2
|
CELA3B
|
chymotrypsin-like elastase family, member 3B |
| chr6_+_33172407 | 6.03 |
ENST00000374662.3
|
HSD17B8
|
hydroxysteroid (17-beta) dehydrogenase 8 |
| chr9_+_135937365 | 6.03 |
ENST00000372080.4
ENST00000351304.7 |
CEL
|
carboxyl ester lipase |
| chr2_-_152590946 | 5.99 |
ENST00000172853.10
|
NEB
|
nebulin |
| chr7_+_130794846 | 5.97 |
ENST00000421797.2
|
MKLN1
|
muskelin 1, intracellular mediator containing kelch motifs |
| chr3_-_46904918 | 5.95 |
ENST00000395869.1
|
MYL3
|
myosin, light chain 3, alkali; ventricular, skeletal, slow |
| chr6_-_10419871 | 5.87 |
ENST00000319516.4
|
TFAP2A
|
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| chr16_-_12009735 | 5.80 |
ENST00000439887.2
ENST00000434724.2 |
GSPT1
|
G1 to S phase transition 1 |
| chr11_-_2182388 | 5.79 |
ENST00000421783.1
ENST00000397262.1 ENST00000250971.3 ENST00000381330.4 ENST00000397270.1 |
INS
INS-IGF2
|
insulin INS-IGF2 readthrough |
| chr1_-_160990886 | 5.73 |
ENST00000537746.1
|
F11R
|
F11 receptor |
| chr2_+_170590321 | 5.72 |
ENST00000392647.2
|
KLHL23
|
kelch-like family member 23 |
| chr8_+_145438870 | 5.65 |
ENST00000527931.1
|
FAM203B
|
family with sequence similarity 203, member B |
| chr14_-_106586656 | 5.48 |
ENST00000390602.2
|
IGHV3-13
|
immunoglobulin heavy variable 3-13 |
| chr12_-_13248732 | 5.47 |
ENST00000396302.3
|
GSG1
|
germ cell associated 1 |
| chr11_+_69455855 | 5.43 |
ENST00000227507.2
ENST00000536559.1 |
CCND1
|
cyclin D1 |
| chr1_+_104293028 | 5.42 |
ENST00000370079.3
|
AMY1C
|
amylase, alpha 1C (salivary) |
| chr3_+_52454971 | 5.40 |
ENST00000465863.1
|
PHF7
|
PHD finger protein 7 |
| chr16_-_11375179 | 5.36 |
ENST00000312511.3
|
PRM1
|
protamine 1 |
| chr11_+_60223312 | 5.35 |
ENST00000532491.1
ENST00000532073.1 ENST00000534668.1 ENST00000528313.1 ENST00000533306.1 |
MS4A1
|
membrane-spanning 4-domains, subfamily A, member 1 |
| chr11_+_71249071 | 5.32 |
ENST00000398534.3
|
KRTAP5-8
|
keratin associated protein 5-8 |
| chr19_+_50936142 | 5.31 |
ENST00000357701.5
|
MYBPC2
|
myosin binding protein C, fast type |
| chr4_-_186456652 | 5.31 |
ENST00000284767.5
ENST00000284770.5 |
PDLIM3
|
PDZ and LIM domain 3 |
| chr11_+_60223225 | 5.28 |
ENST00000524807.1
ENST00000345732.4 |
MS4A1
|
membrane-spanning 4-domains, subfamily A, member 1 |
| chr3_-_167191814 | 5.22 |
ENST00000466903.1
ENST00000264677.4 |
SERPINI2
|
serpin peptidase inhibitor, clade I (pancpin), member 2 |
| chr1_-_40367668 | 5.11 |
ENST00000397332.2
ENST00000429311.1 |
MYCL
|
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| chr18_+_48405419 | 5.09 |
ENST00000321341.5
|
ME2
|
malic enzyme 2, NAD(+)-dependent, mitochondrial |
| chr12_-_13248705 | 5.06 |
ENST00000396310.2
|
GSG1
|
germ cell associated 1 |
| chr4_-_186456766 | 5.04 |
ENST00000284771.6
|
PDLIM3
|
PDZ and LIM domain 3 |
| chr4_-_103748880 | 4.96 |
ENST00000453744.2
ENST00000349311.8 |
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr18_+_48405463 | 4.92 |
ENST00000382927.3
|
ME2
|
malic enzyme 2, NAD(+)-dependent, mitochondrial |
| chr6_-_114292449 | 4.85 |
ENST00000519065.1
|
HDAC2
|
histone deacetylase 2 |
| chr2_-_179672142 | 4.84 |
ENST00000342992.6
ENST00000360870.5 ENST00000460472.2 ENST00000589042.1 ENST00000591111.1 ENST00000342175.6 ENST00000359218.5 |
TTN
|
titin |
| chr20_+_44044717 | 4.78 |
ENST00000279036.6
ENST00000279035.9 ENST00000372689.5 ENST00000545755.1 ENST00000341555.5 ENST00000535404.1 ENST00000543458.2 ENST00000432270.1 |
PIGT
|
phosphatidylinositol glycan anchor biosynthesis, class T |
| chr17_-_39191107 | 4.76 |
ENST00000344363.5
|
KRTAP1-3
|
keratin associated protein 1-3 |
| chr4_-_151936865 | 4.74 |
ENST00000535741.1
|
LRBA
|
LPS-responsive vesicle trafficking, beach and anchor containing |
| chrX_-_153714994 | 4.73 |
ENST00000369660.4
|
UBL4A
|
ubiquitin-like 4A |
| chr8_-_80993010 | 4.69 |
ENST00000537855.1
ENST00000520527.1 ENST00000517427.1 ENST00000448733.2 ENST00000379097.3 |
TPD52
|
tumor protein D52 |
| chr16_+_32077386 | 4.65 |
ENST00000354689.6
|
IGHV3OR16-9
|
immunoglobulin heavy variable 3/OR16-9 (non-functional) |
| chr8_-_103424986 | 4.62 |
ENST00000521922.1
|
UBR5
|
ubiquitin protein ligase E3 component n-recognin 5 |
| chr12_-_13248562 | 4.59 |
ENST00000457134.2
ENST00000537302.1 |
GSG1
|
germ cell associated 1 |
| chr4_-_76598544 | 4.53 |
ENST00000515457.1
ENST00000357854.3 |
G3BP2
|
GTPase activating protein (SH3 domain) binding protein 2 |
| chr2_+_37571717 | 4.51 |
ENST00000338415.3
ENST00000404976.1 |
QPCT
|
glutaminyl-peptide cyclotransferase |
| chr4_-_103749105 | 4.49 |
ENST00000394801.4
ENST00000394804.2 |
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr8_-_103424916 | 4.46 |
ENST00000220959.4
|
UBR5
|
ubiquitin protein ligase E3 component n-recognin 5 |
| chr4_-_103749313 | 4.46 |
ENST00000394803.5
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr7_+_128470431 | 4.30 |
ENST00000325888.8
ENST00000346177.6 |
FLNC
|
filamin C, gamma |
| chr5_-_140053152 | 4.29 |
ENST00000542735.1
|
DND1
|
DND microRNA-mediated repression inhibitor 1 |
| chr5_-_54281407 | 4.22 |
ENST00000381403.4
|
ESM1
|
endothelial cell-specific molecule 1 |
| chr5_-_54281491 | 4.18 |
ENST00000381405.4
|
ESM1
|
endothelial cell-specific molecule 1 |
| chrX_-_118827333 | 4.18 |
ENST00000360156.7
ENST00000354228.4 ENST00000489216.1 ENST00000354416.3 ENST00000394610.1 ENST00000343984.5 |
SEPT6
|
septin 6 |
| chr16_+_30383613 | 4.12 |
ENST00000568749.1
|
MYLPF
|
myosin light chain, phosphorylatable, fast skeletal muscle |
| chr22_+_38245414 | 4.12 |
ENST00000381683.6
ENST00000414316.1 ENST00000406934.1 ENST00000451427.1 |
EIF3L
|
eukaryotic translation initiation factor 3, subunit L |
| chr5_+_68788594 | 4.10 |
ENST00000396442.2
ENST00000380766.2 |
OCLN
|
occludin |
| chr8_-_145018905 | 4.05 |
ENST00000398774.2
|
PLEC
|
plectin |
| chr2_+_37571845 | 4.05 |
ENST00000537448.1
|
QPCT
|
glutaminyl-peptide cyclotransferase |
| chr3_-_50360192 | 4.04 |
ENST00000442581.1
ENST00000447092.1 ENST00000357750.4 |
HYAL2
|
hyaluronoglucosaminidase 2 |
| chr16_-_30006922 | 3.98 |
ENST00000564026.1
|
HIRIP3
|
HIRA interacting protein 3 |
| chr1_-_42384343 | 3.97 |
ENST00000372584.1
|
HIVEP3
|
human immunodeficiency virus type I enhancer binding protein 3 |
| chrX_-_11445856 | 3.97 |
ENST00000380736.1
|
ARHGAP6
|
Rho GTPase activating protein 6 |
| chr16_+_67233412 | 3.96 |
ENST00000477898.1
|
ELMO3
|
engulfment and cell motility 3 |
| chr3_-_49722523 | 3.89 |
ENST00000448220.1
|
MST1
|
macrophage stimulating 1 (hepatocyte growth factor-like) |
| chr10_-_30638090 | 3.89 |
ENST00000421701.1
ENST00000263063.4 |
MTPAP
|
mitochondrial poly(A) polymerase |
| chr22_+_22988816 | 3.82 |
ENST00000480559.1
ENST00000448514.1 |
GGTLC2
|
gamma-glutamyltransferase light chain 2 |
| chr1_-_39339777 | 3.80 |
ENST00000397572.2
|
MYCBP
|
MYC binding protein |
| chr14_-_90085458 | 3.79 |
ENST00000345097.4
ENST00000555855.1 ENST00000555353.1 |
FOXN3
|
forkhead box N3 |
| chr6_-_31938700 | 3.69 |
ENST00000495340.1
|
DXO
|
decapping exoribonuclease |
| chr22_-_37882395 | 3.60 |
ENST00000416983.3
ENST00000424765.2 ENST00000356998.3 |
MFNG
|
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| chr2_-_175113088 | 3.56 |
ENST00000409546.1
ENST00000428402.2 |
OLA1
|
Obg-like ATPase 1 |
| chr15_+_89182156 | 3.51 |
ENST00000379224.5
|
ISG20
|
interferon stimulated exonuclease gene 20kDa |
| chr1_+_26737253 | 3.49 |
ENST00000326279.6
|
LIN28A
|
lin-28 homolog A (C. elegans) |
| chr5_+_34656331 | 3.36 |
ENST00000265109.3
|
RAI14
|
retinoic acid induced 14 |
| chr17_+_40985407 | 3.36 |
ENST00000586114.1
ENST00000590720.1 ENST00000585805.1 ENST00000541124.1 ENST00000441946.2 ENST00000591152.1 ENST00000589469.1 ENST00000293362.3 ENST00000592169.1 |
PSME3
|
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) |
| chr8_-_99837856 | 3.35 |
ENST00000518165.1
ENST00000419617.2 |
STK3
|
serine/threonine kinase 3 |
| chr2_+_220436917 | 3.34 |
ENST00000243786.2
|
INHA
|
inhibin, alpha |
| chr1_-_27216729 | 3.33 |
ENST00000431781.2
ENST00000374135.4 |
GPN2
|
GPN-loop GTPase 2 |
| chr11_-_122931881 | 3.24 |
ENST00000526110.1
ENST00000227378.3 |
HSPA8
|
heat shock 70kDa protein 8 |
| chr11_+_128634589 | 3.22 |
ENST00000281428.8
|
FLI1
|
Fli-1 proto-oncogene, ETS transcription factor |
| chr12_-_53994805 | 3.12 |
ENST00000328463.7
|
ATF7
|
activating transcription factor 7 |
| chr13_+_115000339 | 3.08 |
ENST00000360383.3
ENST00000375312.3 |
CDC16
|
cell division cycle 16 |
| chr14_-_50999307 | 3.01 |
ENST00000013125.4
|
MAP4K5
|
mitogen-activated protein kinase kinase kinase kinase 5 |
| chr1_+_168250194 | 3.00 |
ENST00000367821.3
|
TBX19
|
T-box 19 |
| chr7_+_93535817 | 2.99 |
ENST00000248572.5
|
GNGT1
|
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
| chr1_-_154842741 | 2.93 |
ENST00000271915.4
|
KCNN3
|
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 |
| chr12_+_19282643 | 2.92 |
ENST00000317589.4
ENST00000355397.3 ENST00000359180.3 ENST00000309364.4 ENST00000540972.1 ENST00000429027.2 |
PLEKHA5
|
pleckstrin homology domain containing, family A member 5 |
| chr17_-_46035187 | 2.91 |
ENST00000300557.2
|
PRR15L
|
proline rich 15-like |
| chr2_-_152590982 | 2.89 |
ENST00000409198.1
ENST00000397345.3 ENST00000427231.2 |
NEB
|
nebulin |
| chr11_-_19223523 | 2.89 |
ENST00000265968.3
|
CSRP3
|
cysteine and glycine-rich protein 3 (cardiac LIM protein) |
| chr14_-_37051798 | 2.88 |
ENST00000258829.5
|
NKX2-8
|
NK2 homeobox 8 |
| chr20_-_22566089 | 2.85 |
ENST00000377115.4
|
FOXA2
|
forkhead box A2 |
| chr11_+_7618413 | 2.82 |
ENST00000528883.1
|
PPFIBP2
|
PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| chr13_+_112721913 | 2.81 |
ENST00000330949.1
|
SOX1
|
SRY (sex determining region Y)-box 1 |
| chr14_+_67707826 | 2.79 |
ENST00000261681.4
|
MPP5
|
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| chr1_-_46152174 | 2.77 |
ENST00000290795.3
ENST00000355105.3 |
GPBP1L1
|
GC-rich promoter binding protein 1-like 1 |
| chr1_+_150954493 | 2.76 |
ENST00000368947.4
|
ANXA9
|
annexin A9 |
| chr3_+_182511266 | 2.73 |
ENST00000323116.5
ENST00000493826.1 |
ATP11B
|
ATPase, class VI, type 11B |
| chr1_-_171621815 | 2.73 |
ENST00000037502.6
|
MYOC
|
myocilin, trabecular meshwork inducible glucocorticoid response |
| chr8_-_81083731 | 2.64 |
ENST00000379096.5
|
TPD52
|
tumor protein D52 |
| chr7_-_11871815 | 2.61 |
ENST00000423059.4
|
THSD7A
|
thrombospondin, type I, domain containing 7A |
| chr4_+_169418195 | 2.58 |
ENST00000261509.6
ENST00000335742.7 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr6_+_46761118 | 2.55 |
ENST00000230588.4
|
MEP1A
|
meprin A, alpha (PABA peptide hydrolase) |
| chr14_-_107131560 | 2.50 |
ENST00000390632.2
|
IGHV3-66
|
immunoglobulin heavy variable 3-66 |
| chr10_-_33625154 | 2.46 |
ENST00000265371.4
|
NRP1
|
neuropilin 1 |
| chr17_-_39538550 | 2.45 |
ENST00000394001.1
|
KRT34
|
keratin 34 |
| chr7_+_77428066 | 2.44 |
ENST00000422959.2
ENST00000307305.8 ENST00000424760.1 |
PHTF2
|
putative homeodomain transcription factor 2 |
| chr4_-_139163491 | 2.37 |
ENST00000280612.5
|
SLC7A11
|
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| chr1_-_111991850 | 2.35 |
ENST00000411751.2
|
WDR77
|
WD repeat domain 77 |
| chr19_-_42916499 | 2.30 |
ENST00000601189.1
ENST00000599211.1 |
LIPE
|
lipase, hormone-sensitive |
| chr11_-_117698787 | 2.30 |
ENST00000260287.2
|
FXYD2
|
FXYD domain containing ion transport regulator 2 |
| chr1_-_156675535 | 2.29 |
ENST00000368221.1
|
CRABP2
|
cellular retinoic acid binding protein 2 |
| chr19_-_39881777 | 2.15 |
ENST00000595564.1
ENST00000221265.3 |
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
| chr16_+_103816 | 2.14 |
ENST00000383018.3
ENST00000417493.1 |
SNRNP25
|
small nuclear ribonucleoprotein 25kDa (U11/U12) |
| chr17_-_56429500 | 2.03 |
ENST00000225504.3
|
SUPT4H1
|
suppressor of Ty 4 homolog 1 (S. cerevisiae) |
| chr8_-_103425047 | 2.03 |
ENST00000520539.1
|
UBR5
|
ubiquitin protein ligase E3 component n-recognin 5 |
| chr3_-_49851313 | 1.98 |
ENST00000333486.3
|
UBA7
|
ubiquitin-like modifier activating enzyme 7 |
Network of associatons between targets according to the STRING database.
First level regulatory network of FIGLA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.2 | 21.6 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 7.1 | 21.3 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 6.2 | 30.9 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 5.6 | 16.8 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 5.3 | 16.0 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 4.7 | 37.2 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536) |
| 4.6 | 13.9 | GO:0052027 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 4.2 | 12.6 | GO:1902303 | regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303) |
| 3.8 | 15.4 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 3.5 | 20.7 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 3.0 | 8.9 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 2.9 | 8.6 | GO:0017186 | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) |
| 2.8 | 8.5 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
| 2.8 | 22.6 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 2.8 | 11.2 | GO:0006850 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 2.7 | 8.2 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 2.7 | 21.3 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 2.4 | 7.3 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) |
| 2.2 | 8.9 | GO:0007525 | somatic muscle development(GO:0007525) |
| 1.9 | 7.7 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 1.9 | 5.8 | GO:0033861 | negative regulation of NAD(P)H oxidase activity(GO:0033861) |
| 1.9 | 17.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 1.9 | 24.7 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 1.6 | 11.1 | GO:1901315 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 1.6 | 9.3 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 1.5 | 24.4 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 1.5 | 6.0 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 1.5 | 5.9 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 1.5 | 14.6 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 1.4 | 10.0 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 1.3 | 6.7 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 1.3 | 6.3 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 1.2 | 8.4 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 1.2 | 7.0 | GO:2000980 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 1.1 | 45.9 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 1.1 | 3.3 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 1.1 | 7.7 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 1.0 | 5.1 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 1.0 | 12.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 1.0 | 4.0 | GO:0019087 | transformation of host cell by virus(GO:0019087) |
| 1.0 | 4.8 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) fungiform papilla formation(GO:0061198) |
| 0.9 | 2.8 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 0.9 | 7.5 | GO:0045084 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) |
| 0.9 | 2.7 | GO:0097254 | renal tubular secretion(GO:0097254) |
| 0.8 | 3.3 | GO:0046882 | negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882) |
| 0.8 | 8.2 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.8 | 4.7 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.7 | 3.5 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
| 0.7 | 3.5 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.7 | 10.3 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.7 | 4.8 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.7 | 2.7 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.7 | 2.7 | GO:0014734 | skeletal muscle hypertrophy(GO:0014734) |
| 0.7 | 20.7 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
| 0.6 | 3.2 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 0.6 | 26.2 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.6 | 8.5 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.5 | 6.0 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.5 | 1.5 | GO:0072312 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
| 0.5 | 2.5 | GO:1905040 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.5 | 2.3 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.5 | 34.7 | GO:0010257 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.5 | 6.3 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
| 0.4 | 4.7 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.4 | 2.1 | GO:0002913 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) |
| 0.4 | 6.0 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.4 | 2.8 | GO:0060573 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.4 | 4.3 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
| 0.4 | 1.2 | GO:0002232 | leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 0.4 | 23.5 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.4 | 2.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.4 | 19.3 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.3 | 8.5 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.3 | 1.0 | GO:0060448 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
| 0.3 | 5.7 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.3 | 9.5 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.3 | 3.9 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.3 | 1.8 | GO:2000568 | memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568) |
| 0.3 | 4.5 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.3 | 11.3 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.3 | 12.2 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 0.3 | 10.3 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 0.3 | 3.9 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.3 | 4.1 | GO:0070673 | response to interleukin-18(GO:0070673) |
| 0.3 | 3.8 | GO:1901748 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.3 | 6.8 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.3 | 3.7 | GO:0071027 | nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
| 0.3 | 6.6 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.2 | 2.0 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.2 | 2.0 | GO:0045656 | negative regulation of monocyte differentiation(GO:0045656) |
| 0.2 | 0.7 | GO:0031630 | regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630) |
| 0.2 | 6.7 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.2 | 5.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.2 | 0.7 | GO:0032900 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.2 | 3.8 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.2 | 0.7 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.2 | 1.3 | GO:1904706 | negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
| 0.2 | 2.2 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.2 | 0.9 | GO:0060023 | soft palate development(GO:0060023) |
| 0.2 | 1.5 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
| 0.2 | 27.7 | GO:0031424 | keratinization(GO:0031424) |
| 0.2 | 1.2 | GO:0046886 | positive regulation of hormone biosynthetic process(GO:0046886) |
| 0.2 | 6.2 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.2 | 1.8 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 0.2 | 4.0 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) |
| 0.2 | 29.7 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
| 0.2 | 3.2 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.2 | 2.0 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.2 | 5.4 | GO:0030261 | chromosome condensation(GO:0030261) |
| 0.2 | 5.1 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.2 | 0.8 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.2 | 2.7 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.2 | 2.0 | GO:0051775 | response to redox state(GO:0051775) |
| 0.1 | 2.8 | GO:0008105 | asymmetric protein localization(GO:0008105) |
| 0.1 | 0.7 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.1 | 1.2 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.1 | 1.8 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.1 | 3.0 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 10.3 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.1 | 1.4 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.1 | 8.7 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.1 | 10.6 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.1 | 4.0 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.1 | 1.9 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.1 | 0.7 | GO:0038129 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129) |
| 0.1 | 0.5 | GO:0048852 | hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852) |
| 0.1 | 1.2 | GO:0042789 | mRNA transcription from RNA polymerase II promoter(GO:0042789) |
| 0.1 | 0.9 | GO:2000121 | regulation of removal of superoxide radicals(GO:2000121) |
| 0.1 | 3.0 | GO:0048747 | muscle fiber development(GO:0048747) |
| 0.1 | 3.6 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.1 | 0.4 | GO:0032423 | regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425) |
| 0.1 | 1.4 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.1 | 3.0 | GO:0021983 | pituitary gland development(GO:0021983) |
| 0.1 | 1.4 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.1 | 8.7 | GO:0006446 | regulation of translational initiation(GO:0006446) |
| 0.1 | 0.3 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.1 | 1.9 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.1 | 2.4 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
| 0.1 | 6.9 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.1 | 0.7 | GO:0015865 | purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868) |
| 0.1 | 6.4 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
| 0.1 | 1.0 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.1 | 0.5 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
| 0.1 | 0.9 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.1 | 3.8 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 1.9 | GO:0031102 | neuron projection regeneration(GO:0031102) |
| 0.0 | 1.9 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 6.9 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 3.6 | GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) |
| 0.0 | 0.3 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.0 | 0.7 | GO:0048536 | spleen development(GO:0048536) |
| 0.0 | 4.0 | GO:0006333 | chromatin assembly or disassembly(GO:0006333) |
| 0.0 | 2.0 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 1.2 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.1 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.0 | 0.6 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.6 | GO:0010644 | cell communication by electrical coupling(GO:0010644) |
| 0.0 | 1.9 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 0.4 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 2.6 | GO:0007586 | digestion(GO:0007586) |
| 0.0 | 7.8 | GO:0048232 | spermatogenesis(GO:0007283) male gamete generation(GO:0048232) |
| 0.0 | 3.4 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.0 | 2.5 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.0 | 1.6 | GO:0042742 | defense response to bacterium(GO:0042742) |
| 0.0 | 2.9 | GO:0061458 | reproductive system development(GO:0061458) |
| 0.0 | 3.1 | GO:0043687 | post-translational protein modification(GO:0043687) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.5 | 22.6 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 7.1 | 21.3 | GO:0018444 | translation release factor complex(GO:0018444) |
| 5.2 | 30.9 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 2.8 | 8.5 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
| 2.5 | 12.6 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 2.3 | 6.9 | GO:1990393 | 3M complex(GO:1990393) |
| 2.1 | 16.8 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 2.1 | 10.3 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 1.6 | 4.8 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 1.4 | 8.5 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 1.4 | 42.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 1.4 | 15.4 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 1.3 | 17.2 | GO:0042555 | MCM complex(GO:0042555) |
| 1.2 | 22.9 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 1.2 | 30.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 1.2 | 4.7 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 1.1 | 3.3 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 1.0 | 26.0 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.8 | 26.4 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.7 | 5.7 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.7 | 12.9 | GO:0034709 | methylosome(GO:0034709) |
| 0.7 | 6.2 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.6 | 27.2 | GO:0045095 | keratin filament(GO:0045095) |
| 0.6 | 3.4 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.6 | 14.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.5 | 1.5 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 0.5 | 1.5 | GO:0005608 | laminin-3 complex(GO:0005608) |
| 0.5 | 2.0 | GO:0032044 | DSIF complex(GO:0032044) |
| 0.5 | 2.8 | GO:0043219 | lateral loop(GO:0043219) |
| 0.5 | 3.2 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.4 | 11.2 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.4 | 2.4 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.4 | 1.1 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.4 | 10.8 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.3 | 4.2 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.3 | 27.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.3 | 6.3 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.3 | 16.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.3 | 6.3 | GO:0005861 | troponin complex(GO:0005861) |
| 0.3 | 21.2 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.3 | 16.9 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.3 | 4.0 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.2 | 2.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.2 | 16.0 | GO:0015030 | Cajal body(GO:0015030) |
| 0.2 | 2.5 | GO:0002116 | semaphorin receptor complex(GO:0002116) sorting endosome(GO:0097443) |
| 0.2 | 18.2 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.2 | 4.1 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.2 | 2.1 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.2 | 15.2 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.2 | 8.7 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.2 | 2.7 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.2 | 0.5 | GO:0016935 | glycine-gated chloride channel complex(GO:0016935) |
| 0.1 | 2.1 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.1 | 3.0 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.1 | 5.4 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 3.6 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 0.9 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 1.8 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.1 | 1.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 8.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 13.3 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 12.5 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 1.1 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 1.3 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.9 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 3.1 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.1 | 37.5 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.1 | 8.8 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 5.0 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 7.5 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 0.5 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 3.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 79.2 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 2.3 | GO:0031672 | A band(GO:0031672) |
| 0.1 | 0.3 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.1 | 30.9 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 13.9 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 1.9 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.0 | 0.6 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 12.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 1.8 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 13.8 | GO:0005815 | microtubule organizing center(GO:0005815) |
| 0.0 | 3.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 2.4 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 2.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 4.5 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 11.2 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.2 | 21.6 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 5.2 | 20.7 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 5.2 | 20.7 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 4.9 | 24.4 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 4.5 | 22.6 | GO:0019798 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 3.5 | 21.3 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 3.4 | 16.8 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 2.9 | 8.6 | GO:0016603 | glutaminyl-peptide cyclotransferase activity(GO:0016603) |
| 2.8 | 8.4 | GO:0005171 | hepatocyte growth factor receptor binding(GO:0005171) |
| 2.7 | 8.2 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 2.6 | 7.7 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 2.5 | 7.5 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 2.4 | 7.3 | GO:0004515 | nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 2.2 | 6.7 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 2.1 | 12.6 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 1.7 | 8.5 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 1.7 | 78.4 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 1.7 | 10.0 | GO:0004473 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948) |
| 1.6 | 4.8 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 1.6 | 9.3 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 1.4 | 8.5 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 1.4 | 11.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 1.3 | 3.9 | GO:0001884 | pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 1.2 | 3.7 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 1.2 | 6.0 | GO:0070404 | NADH binding(GO:0070404) |
| 1.2 | 6.0 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 1.1 | 26.0 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 1.0 | 4.0 | GO:0033906 | protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906) |
| 0.9 | 15.4 | GO:0003906 | AT DNA binding(GO:0003680) DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.9 | 3.6 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.9 | 19.9 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.8 | 24.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.8 | 2.3 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.7 | 11.1 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.7 | 10.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.6 | 2.9 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.6 | 49.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.5 | 3.4 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.5 | 13.9 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.5 | 8.6 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.5 | 2.4 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 0.5 | 12.2 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
| 0.4 | 11.2 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.4 | 23.2 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.4 | 7.8 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.4 | 3.3 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.4 | 30.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.4 | 7.6 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.4 | 16.9 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.4 | 22.2 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.4 | 3.5 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.3 | 14.9 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.3 | 2.0 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.3 | 20.1 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.3 | 1.8 | GO:0023030 | MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030) |
| 0.3 | 1.5 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.3 | 1.2 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.3 | 1.1 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.3 | 2.5 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.3 | 3.8 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.3 | 2.7 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.3 | 3.5 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.2 | 9.5 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.2 | 1.2 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.2 | 63.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.2 | 4.3 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.2 | 6.7 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.2 | 17.1 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.2 | 0.8 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.2 | 8.7 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.2 | 3.0 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.2 | 5.8 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.2 | 7.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.2 | 5.1 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 1.8 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.1 | 24.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 2.2 | GO:0016918 | retinal binding(GO:0016918) |
| 0.1 | 1.5 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.1 | 3.0 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 1.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 2.7 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 11.1 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 1.9 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.6 | GO:1903763 | gap junction channel activity involved in cell communication by electrical coupling(GO:1903763) |
| 0.1 | 0.7 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
| 0.1 | 0.5 | GO:0016933 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
| 0.1 | 0.4 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 0.1 | 0.7 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 11.4 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.1 | 1.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 1.8 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 6.2 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.1 | 1.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 6.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.5 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 1.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 19.5 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.1 | 2.0 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 0.2 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.1 | 5.8 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 21.1 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 1.2 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.9 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 4.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 2.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.4 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.0 | 0.9 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 0.4 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 1.6 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.3 | GO:0033612 | receptor serine/threonine kinase binding(GO:0033612) transmembrane receptor protein serine/threonine kinase binding(GO:0070696) BMP receptor binding(GO:0070700) |
| 0.0 | 0.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.5 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
| 0.0 | 1.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.4 | GO:0015485 | cholesterol binding(GO:0015485) sterol binding(GO:0032934) |
| 0.0 | 0.3 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 1.0 | GO:0030674 | protein binding, bridging(GO:0030674) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 41.1 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.3 | 18.3 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.3 | 5.4 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.3 | 69.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 10.6 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.2 | 15.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.2 | 17.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.2 | 14.2 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.2 | 2.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.2 | 10.3 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 7.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.2 | 8.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 5.7 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 5.8 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 3.1 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 3.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.0 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.1 | 3.0 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.1 | 3.1 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 3.9 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.1 | 3.0 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.1 | 5.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 4.1 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 4.5 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 1.1 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 1.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 1.6 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 3.2 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.8 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 3.4 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 2.2 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 1.4 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 1.2 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.0 | 0.9 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 1.0 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.5 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.6 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 4.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 15.4 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 1.5 | 42.0 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 1.2 | 20.7 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 1.1 | 26.0 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 1.1 | 17.2 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 1.1 | 38.6 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 1.0 | 22.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.9 | 24.7 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.9 | 60.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.9 | 14.7 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.5 | 5.4 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.4 | 15.2 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.4 | 8.5 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.3 | 25.9 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.3 | 7.7 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.3 | 23.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.3 | 17.4 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.3 | 10.8 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.3 | 5.1 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.3 | 6.7 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.2 | 21.6 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.2 | 3.3 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.2 | 19.1 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.2 | 10.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 4.1 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.2 | 4.0 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.2 | 4.3 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.2 | 6.4 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.2 | 4.3 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.2 | 2.1 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.2 | 4.8 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.2 | 9.5 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 1.2 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 7.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 6.2 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.1 | 4.1 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 16.8 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.1 | 3.0 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.1 | 2.7 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 2.5 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 4.5 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 12.2 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 2.3 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 3.5 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 2.0 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 1.3 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 2.7 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 2.0 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 10.1 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 3.5 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.1 | 1.9 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.7 | REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | Genes involved in Activation of Kainate Receptors upon glutamate binding |
| 0.0 | 8.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 1.1 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.7 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 1.3 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.4 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.4 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 0.5 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |