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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for FOXA2_FOXJ3

Z-value: 0.18

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Transcription factors associated with FOXA2_FOXJ3

Gene Symbol Gene ID Gene Info
ENSG00000125798.10 forkhead box A2
ENSG00000198815.4 forkhead box J3

Activity profile of FOXA2_FOXJ3 motif

Sorted Z-values of FOXA2_FOXJ3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_70329118 32.32 ENST00000374188.3
interleukin 2 receptor, gamma
chr10_+_70847852 25.04 ENST00000242465.3
serglycin
chr12_-_92539614 22.33 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr4_-_174256276 18.92 ENST00000296503.5
high mobility group box 2
chr5_-_98262240 18.58 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr1_-_207095324 16.85 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr7_-_37026108 16.75 ENST00000396045.3
engulfment and cell motility 1
chr1_+_198608146 15.52 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr1_+_150122034 14.02 ENST00000025469.6
ENST00000369124.4
pleckstrin homology domain containing, family O member 1
chr19_-_9546177 13.93 ENST00000592292.1
ENST00000588221.1
zinc finger protein 266
chr2_+_58655461 13.62 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr22_-_43036607 13.61 ENST00000505920.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr1_+_73771844 13.20 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
chr12_-_76462713 12.70 ENST00000552056.1
nucleosome assembly protein 1-like 1
chr2_+_109223595 12.41 ENST00000410093.1
LIM and senescent cell antigen-like domains 1
chr8_+_11666649 11.50 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr8_-_80993010 11.12 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr13_-_46756351 10.90 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr5_+_159436120 10.89 ENST00000522793.1
ENST00000231238.5
tetratricopeptide repeat domain 1
chr14_+_88471468 10.78 ENST00000267549.3
G protein-coupled receptor 65
chr1_-_207095212 10.73 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr19_-_39826639 10.20 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chrX_-_122756660 10.14 ENST00000441692.1
THO complex 2
chr13_-_99910673 9.96 ENST00000397473.2
ENST00000397470.2
G protein-coupled receptor 18
chr3_-_185641681 9.96 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chr2_+_12857043 9.48 ENST00000381465.2
tribbles pseudokinase 2
chr18_+_21032781 9.15 ENST00000339486.3
RIO kinase 3
chr2_+_68592305 9.05 ENST00000234313.7
pleckstrin
chr10_-_73848086 8.91 ENST00000536168.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_+_26332645 8.48 ENST00000396376.1
sorting nexin 10
chrX_+_9431324 8.45 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr1_+_192544857 8.31 ENST00000367459.3
ENST00000469578.2
regulator of G-protein signaling 1
chr12_-_51718436 8.31 ENST00000544402.1
bridging integrator 2
chr14_-_60632162 8.06 ENST00000557185.1
dehydrogenase/reductase (SDR family) member 7
chr20_-_62582475 8.05 ENST00000369908.5
uridine-cytidine kinase 1-like 1
chr17_-_30228678 7.88 ENST00000261708.4
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr3_-_64009658 7.85 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr9_+_70856397 7.76 ENST00000360171.6
COBW domain containing 3
chr17_-_685493 7.72 ENST00000536578.1
ENST00000301328.5
ENST00000576419.1
glyoxalase domain containing 4
chr16_+_84801852 7.53 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr14_-_60632011 7.46 ENST00000554101.1
ENST00000557137.1
dehydrogenase/reductase (SDR family) member 7
chr10_-_103578182 7.38 ENST00000439817.1
meningioma expressed antigen 5 (hyaluronidase)
chr10_-_103578162 7.29 ENST00000361464.3
ENST00000357797.5
ENST00000370094.3
meningioma expressed antigen 5 (hyaluronidase)
chr5_+_54398463 7.11 ENST00000274306.6
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr6_-_42016385 7.10 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
cyclin D3
chr5_-_131132658 7.09 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr5_+_162932554 7.06 ENST00000321757.6
ENST00000421814.2
ENST00000518095.1
methionine adenosyltransferase II, beta
chr16_-_28857677 7.02 ENST00000313511.3
Tu translation elongation factor, mitochondrial
chr9_-_70490107 6.81 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
COBW domain containing 5
chr5_+_147774275 6.75 ENST00000513826.1
F-box protein 38
chr1_+_117297007 6.66 ENST00000369478.3
ENST00000369477.1
CD2 molecule
chr6_+_37012607 6.61 ENST00000423336.1
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr20_+_36373032 6.59 ENST00000373473.1
catenin, beta like 1
chr11_-_67374177 6.54 ENST00000333139.3
chromosome 11 open reading frame 72
chr10_+_111985713 6.42 ENST00000239007.7
MAX interactor 1, dimerization protein
chr15_-_40600026 6.35 ENST00000456256.2
ENST00000557821.1
phospholipase C, beta 2
chr6_-_122792919 6.22 ENST00000339697.4
serine incorporator 1
chr1_+_95616933 6.14 ENST00000604203.1
TMEM56-RWDD3 readthrough
chr16_+_30064444 6.12 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
aldolase A, fructose-bisphosphate
chr8_-_101321584 6.04 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr4_+_147096837 6.04 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr5_+_176853702 6.01 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
G protein-coupled receptor kinase 6
chr7_+_106809406 5.95 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HMG-box transcription factor 1
chr17_-_29641104 5.94 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr16_+_30064411 5.91 ENST00000338110.5
aldolase A, fructose-bisphosphate
chr11_+_126173647 5.87 ENST00000263579.4
decapping enzyme, scavenger
chr22_-_39268308 5.85 ENST00000407418.3
chromobox homolog 6
chr1_+_174844645 5.82 ENST00000486220.1
RAB GTPase activating protein 1-like
chr14_+_97263641 5.69 ENST00000216639.3
vaccinia related kinase 1
chr12_+_54892550 5.66 ENST00000545638.2
NCK-associated protein 1-like
chr5_+_176853669 5.65 ENST00000355472.5
G protein-coupled receptor kinase 6
chr4_-_140223614 5.63 ENST00000394223.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr12_-_68696652 5.62 ENST00000539972.1
Mdm1 nuclear protein homolog (mouse)
chr2_-_170430277 5.58 ENST00000438035.1
ENST00000453929.2
FAST kinase domains 1
chr11_+_102217936 5.58 ENST00000532832.1
ENST00000530675.1
ENST00000533742.1
ENST00000227758.2
ENST00000532672.1
ENST00000531259.1
ENST00000527465.1
baculoviral IAP repeat containing 2
chr4_-_164534657 5.52 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr5_+_32531893 5.51 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr15_+_42697065 5.39 ENST00000565559.1
calpain 3, (p94)
chr2_+_109204909 5.38 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr1_+_174846570 5.38 ENST00000392064.2
RAB GTPase activating protein 1-like
chr7_-_23571586 5.27 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
transformer 2 alpha homolog (Drosophila)
chr2_-_86422523 5.23 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
inner membrane protein, mitochondrial
chr1_+_84609944 5.22 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_3595181 5.20 ENST00000552050.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr1_+_144811744 5.17 ENST00000338347.4
ENST00000440491.2
ENST00000375552.4
neuroblastoma breakpoint family, member 9
chr16_-_24942411 5.14 ENST00000571843.1
Rho GTPase activating protein 17
chr1_+_144811943 5.11 ENST00000281815.8
neuroblastoma breakpoint family, member 9
chr4_-_170679024 5.02 ENST00000393381.2
chromosome 4 open reading frame 27
chr6_-_32160622 4.95 ENST00000487761.1
ENST00000375040.3
G-protein signaling modulator 3
chr12_+_59989918 4.93 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr16_-_28634874 4.92 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr2_+_102413726 4.90 ENST00000350878.4
mitogen-activated protein kinase kinase kinase kinase 4
chr16_-_2314222 4.87 ENST00000566397.1
RNA binding protein S1, serine-rich domain
chr19_+_18208603 4.77 ENST00000262811.6
microtubule associated serine/threonine kinase 3
chr7_-_144435985 4.75 ENST00000549981.1
thiamin pyrophosphokinase 1
chr1_+_158815588 4.74 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr14_-_58893832 4.74 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr1_-_3566627 4.73 ENST00000419924.2
ENST00000270708.7
WD repeat containing, antisense to TP73
chr2_+_114195268 4.59 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
COBW domain containing 2
chr7_+_112063192 4.59 ENST00000005558.4
interferon-related developmental regulator 1
chr1_-_241803679 4.57 ENST00000331838.5
opsin 3
chr14_-_58894223 4.55 ENST00000555593.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr12_-_49582978 4.55 ENST00000301071.7
tubulin, alpha 1a
chr1_-_241803649 4.54 ENST00000366554.2
opsin 3
chr12_-_58240470 4.39 ENST00000548823.1
ENST00000398073.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr7_-_6098770 4.32 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
eukaryotic translation initiation factor 2-alpha kinase 1
chr14_+_35747825 4.32 ENST00000540871.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr4_-_90756769 4.27 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr1_-_161193349 4.22 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
apolipoprotein A-II
chr14_+_56127989 4.21 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr1_+_203830703 4.19 ENST00000414487.2
small nuclear ribonucleoprotein polypeptide E
chr3_+_69928256 4.16 ENST00000394355.2
microphthalmia-associated transcription factor
chr2_-_170430366 4.16 ENST00000453153.2
ENST00000445210.1
FAST kinase domains 1
chr14_+_102276209 4.16 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
protein phosphatase 2, regulatory subunit B', gamma
chr4_-_90757364 4.13 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr8_+_31497271 4.05 ENST00000520407.1
neuregulin 1
chr1_-_3566590 3.99 ENST00000424367.1
ENST00000378322.3
WD repeat containing, antisense to TP73
chr2_+_65283506 3.97 ENST00000377990.2
centrosomal protein 68kDa
chr3_+_101292939 3.94 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PEST proteolytic signal containing nuclear protein
chr3_+_157828152 3.93 ENST00000476899.1
arginine/serine-rich coiled-coil 1
chr5_-_88119580 3.92 ENST00000539796.1
myocyte enhancer factor 2C
chr4_+_57845024 3.90 ENST00000431623.2
ENST00000441246.2
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr1_+_74701062 3.83 ENST00000326637.3
TNNI3 interacting kinase
chr1_+_207943667 3.81 ENST00000462968.2
CD46 molecule, complement regulatory protein
chr1_-_28559502 3.76 ENST00000263697.4
DnaJ (Hsp40) homolog, subfamily C, member 8
chr17_-_56350797 3.75 ENST00000577220.1
myeloperoxidase
chr2_+_65283529 3.73 ENST00000546106.1
ENST00000537589.1
ENST00000260569.4
centrosomal protein 68kDa
chr1_+_145883868 3.71 ENST00000447947.2
G protein-coupled receptor 89C
chr15_+_64680003 3.67 ENST00000261884.3
thyroid hormone receptor interactor 4
chr19_+_14491948 3.64 ENST00000358600.3
CD97 molecule
chr12_+_21525818 3.64 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chrX_-_106959631 3.59 ENST00000486554.1
ENST00000372390.4
TSC22 domain family, member 3
chr8_-_101962777 3.55 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr4_+_154622652 3.53 ENST00000260010.6
toll-like receptor 2
chr7_-_115670804 3.47 ENST00000320239.7
transcription factor EC
chr12_+_56435637 3.47 ENST00000356464.5
ENST00000552361.1
ribosomal protein S26
chr7_-_115670792 3.47 ENST00000265440.7
ENST00000393485.1
transcription factor EC
chr17_+_41561317 3.46 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr3_-_49066811 3.46 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr13_-_49975632 3.45 ENST00000457041.1
ENST00000355854.4
calcium binding protein 39-like
chr3_+_98451093 3.44 ENST00000483910.1
ENST00000460774.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr6_-_131949305 3.43 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
mediator complex subunit 23
chr12_+_53836339 3.40 ENST00000549135.1
proline rich 13
chr16_+_81812863 3.38 ENST00000359376.3
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr2_+_143635067 3.37 ENST00000264170.4
kynureninase
chr19_-_18433910 3.36 ENST00000594828.3
ENST00000593829.1
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_+_56078695 3.33 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr17_-_26662440 3.29 ENST00000578122.1
intraflagellar transport 20 homolog (Chlamydomonas)
chr16_-_21663919 3.28 ENST00000569602.1
immunoglobulin superfamily, member 6
chr14_-_95624227 3.26 ENST00000526495.1
dicer 1, ribonuclease type III
chr6_+_74171301 3.24 ENST00000415954.2
ENST00000498286.1
ENST00000370305.1
ENST00000370300.4
mitochondrial tRNA translation optimization 1
chr10_+_111967345 3.22 ENST00000332674.5
ENST00000453116.1
MAX interactor 1, dimerization protein
chr7_-_139876812 3.20 ENST00000397560.2
lysine (K)-specific demethylase 7A
chr5_-_150460539 3.12 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNFAIP3 interacting protein 1
chr12_+_32832134 3.07 ENST00000452533.2
dynamin 1-like
chr4_-_153332886 3.04 ENST00000603841.1
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_+_156607829 3.01 ENST00000422843.3
IL2-inducible T-cell kinase
chr14_-_102605983 3.00 ENST00000334701.7
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr7_+_77469439 3.00 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr7_-_76829125 2.99 ENST00000248598.5
fibrinogen-like 2
chrX_+_40440146 2.96 ENST00000535539.1
ENST00000378438.4
ENST00000436783.1
ENST00000544975.1
ENST00000535777.1
ENST00000447485.1
ENST00000423649.1
ATPase, H+ transporting, lysosomal accessory protein 2
chr21_+_34602377 2.96 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
interferon (alpha, beta and omega) receptor 2
chr8_+_26247878 2.95 ENST00000518611.1
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr13_+_41885341 2.95 ENST00000379406.3
ENST00000379367.3
ENST00000403412.3
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr1_-_1342617 2.95 ENST00000482352.1
ENST00000344843.7
mitochondrial ribosomal protein L20
chr16_+_56969284 2.94 ENST00000568358.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_-_42185583 2.93 ENST00000053468.3
mitochondrial ribosomal protein S10
chr5_+_96212185 2.88 ENST00000379904.4
endoplasmic reticulum aminopeptidase 2
chr11_-_9286921 2.88 ENST00000328194.3
DENN/MADD domain containing 5A
chr7_+_80275953 2.84 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr3_-_15382875 2.79 ENST00000408919.3
SH3-domain binding protein 5 (BTK-associated)
chr3_-_150920979 2.77 ENST00000309180.5
ENST00000480322.1
G protein-coupled receptor 171
chr11_+_67374323 2.77 ENST00000322776.6
ENST00000532303.1
ENST00000532244.1
ENST00000528328.1
ENST00000529927.1
ENST00000532343.1
ENST00000415352.2
ENST00000533075.1
ENST00000529867.1
ENST00000530638.1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr20_+_48552908 2.77 ENST00000244061.2
ring finger protein 114
chr2_-_27886460 2.75 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
suppressor of Ty 7 (S. cerevisiae)-like
chr18_+_21033239 2.74 ENST00000581585.1
ENST00000577501.1
RIO kinase 3
chr1_+_161123536 2.73 ENST00000368003.5
ubiquitin-fold modifier conjugating enzyme 1
chrX_+_77154935 2.67 ENST00000481445.1
cytochrome c oxidase subunit VIIb
chr1_+_52082751 2.63 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
oxysterol binding protein-like 9
chr17_-_29641084 2.63 ENST00000544462.1
ecotropic viral integration site 2B
chr1_-_169555779 2.61 ENST00000367797.3
ENST00000367796.3
coagulation factor V (proaccelerin, labile factor)
chr7_+_149570049 2.59 ENST00000421974.2
ENST00000456496.2
ATPase, H+ transporting V0 subunit e2
chr15_+_58430368 2.59 ENST00000558772.1
ENST00000219919.4
aquaporin 9
chr4_+_79567314 2.56 ENST00000503539.1
ENST00000504675.1
long intergenic non-protein coding RNA 1094
chr3_-_105588231 2.53 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr16_+_28858004 2.53 ENST00000322610.8
SH2B adaptor protein 1
chr14_+_102276132 2.51 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
protein phosphatase 2, regulatory subunit B', gamma
chr10_-_99094458 2.50 ENST00000371019.2
frequently rearranged in advanced T-cell lymphomas 2
chr14_+_57046530 2.49 ENST00000536419.1
ENST00000538838.1
transmembrane protein 260
chr19_+_36630454 2.48 ENST00000246533.3
calpain, small subunit 1
chr11_-_47447767 2.47 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr21_-_33975547 2.41 ENST00000431599.1
chromosome 21 open reading frame 59
chr2_+_109204743 2.39 ENST00000332345.6
LIM and senescent cell antigen-like domains 1
chr20_+_36322408 2.38 ENST00000361383.6
ENST00000447935.1
ENST00000405275.2
catenin, beta like 1
chr6_-_131949200 2.37 ENST00000539158.1
ENST00000368058.1
mediator complex subunit 23
chr15_+_58430567 2.36 ENST00000536493.1
aquaporin 9
chr1_+_87797351 2.36 ENST00000370542.1
LIM domain only 4
chr7_+_80275752 2.35 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr15_+_42697018 2.35 ENST00000397204.4
calpain 3, (p94)
chr7_+_80275621 2.35 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA2_FOXJ3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 25.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
4.6 32.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
3.1 15.5 GO:0048539 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
3.0 11.9 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
2.5 10.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
2.3 11.5 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
1.9 9.5 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
1.9 18.9 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.9 5.6 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
1.8 7.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.7 22.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.7 5.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
1.7 8.4 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
1.5 4.6 GO:0097052 tryptophan catabolic process to acetyl-CoA(GO:0019442) L-kynurenine metabolic process(GO:0097052)
1.5 4.6 GO:0007518 myoblast fate determination(GO:0007518)
1.5 9.0 GO:0070560 protein secretion by platelet(GO:0070560)
1.5 10.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.4 13.0 GO:0071724 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
1.4 15.6 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
1.4 4.2 GO:2000909 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
1.4 8.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
1.3 8.0 GO:0044211 CTP salvage(GO:0044211)
1.3 7.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.2 4.8 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
1.2 1.2 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
1.1 10.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.1 3.4 GO:0002316 follicular B cell differentiation(GO:0002316) activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
1.1 6.7 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885) positive regulation of interferon-gamma secretion(GO:1902715)
1.1 3.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
1.1 4.3 GO:0006447 regulation of translational initiation by iron(GO:0006447)
1.1 14.0 GO:0051451 myoblast migration(GO:0051451)
1.0 5.2 GO:0097338 response to clozapine(GO:0097338)
1.0 3.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.0 10.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
1.0 4.9 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
1.0 3.9 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.9 7.4 GO:0090166 Golgi disassembly(GO:0090166)
0.9 3.5 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.9 14.7 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.8 18.6 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.8 5.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.8 2.3 GO:1901355 response to rapamycin(GO:1901355)
0.8 2.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.7 3.0 GO:0043335 protein unfolding(GO:0043335)
0.7 7.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.7 2.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.7 2.1 GO:0051685 maintenance of ER location(GO:0051685)
0.7 2.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.6 11.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.6 4.9 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.6 9.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.6 3.0 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.6 9.5 GO:0051639 actin filament network formation(GO:0051639)
0.6 1.8 GO:1902896 terminal web assembly(GO:1902896)
0.6 4.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.6 3.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.6 2.3 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.5 6.4 GO:0015825 L-serine transport(GO:0015825)
0.5 1.6 GO:0021764 amygdala development(GO:0021764)
0.5 2.6 GO:0032571 response to vitamin K(GO:0032571)
0.5 3.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.5 3.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.5 1.9 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.5 4.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.5 3.8 GO:0001878 response to yeast(GO:0001878)
0.5 16.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.4 3.6 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 8.3 GO:0097320 membrane tubulation(GO:0097320)
0.4 8.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.4 5.2 GO:0042407 cristae formation(GO:0042407)
0.4 5.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.4 7.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.4 20.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 3.6 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.4 20.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.4 2.7 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.4 8.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.4 3.8 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.4 1.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.4 3.0 GO:0048069 positive regulation of transforming growth factor beta1 production(GO:0032914) eye pigmentation(GO:0048069)
0.4 10.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.4 3.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.4 3.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 3.0 GO:0001865 NK T cell differentiation(GO:0001865)
0.3 13.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 1.9 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.3 9.6 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.3 2.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 13.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.3 8.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.3 3.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.3 4.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 2.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 1.7 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 2.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 6.0 GO:0006068 ethanol catabolic process(GO:0006068) sulfation(GO:0051923)
0.2 3.5 GO:0090168 Golgi reassembly(GO:0090168)
0.2 1.6 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.2 2.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 8.3 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.2 4.7 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.2 5.4 GO:0030183 B cell differentiation(GO:0030183)
0.2 2.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 5.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.2 5.7 GO:0097503 sialylation(GO:0097503)
0.2 2.4 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.2 2.9 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.2 7.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 2.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.2 0.6 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 1.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 4.5 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 4.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.2 1.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.2 10.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 7.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 7.9 GO:0019985 translesion synthesis(GO:0019985)
0.2 4.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.1 1.0 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 12.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.9 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 2.5 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 0.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 1.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 2.8 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 8.2 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.1 9.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 3.5 GO:0035456 response to interferon-beta(GO:0035456)
0.1 1.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 14.1 GO:0006334 nucleosome assembly(GO:0006334)
0.1 4.2 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.1 2.6 GO:0007035 vacuolar acidification(GO:0007035)
0.1 2.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 8.9 GO:0045333 cellular respiration(GO:0045333)
0.1 1.3 GO:0006301 postreplication repair(GO:0006301)
0.1 1.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 6.0 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.1 2.9 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 1.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 7.1 GO:0016575 histone deacetylation(GO:0016575)
0.1 5.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 3.3 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.1 1.0 GO:0002021 response to dietary excess(GO:0002021)
0.1 1.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 3.2 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.7 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 8.1 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 6.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 2.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.5 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 2.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.3 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 2.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 4.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.8 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 1.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 2.3 GO:0046324 regulation of glucose import(GO:0046324)
0.0 2.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 3.0 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.2 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.7 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 5.6 GO:0006457 protein folding(GO:0006457)
0.0 0.0 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 3.1 GO:0007018 microtubule-based movement(GO:0007018)
0.0 4.6 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.0 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 1.6 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 1.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 2.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
2.6 10.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
2.4 7.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.6 7.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.6 4.7 GO:1902636 kinociliary basal body(GO:1902636)
1.5 11.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.4 10.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.4 8.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
1.4 16.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.3 3.8 GO:0002079 inner acrosomal membrane(GO:0002079)
1.2 3.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
1.1 19.2 GO:0001891 phagocytic cup(GO:0001891)
1.0 20.9 GO:0042588 zymogen granule(GO:0042588)
0.9 9.4 GO:0005688 U6 snRNP(GO:0005688)
0.8 13.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.7 5.2 GO:0061617 MICOS complex(GO:0061617)
0.6 1.8 GO:0044393 microspike(GO:0044393)
0.6 17.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 2.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.5 4.9 GO:0061574 ASAP complex(GO:0061574)
0.5 4.2 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.5 2.9 GO:1990037 Lewy body core(GO:1990037)
0.4 1.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.4 3.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.4 9.0 GO:0000974 Prp19 complex(GO:0000974)
0.4 3.0 GO:0031415 NatA complex(GO:0031415)
0.4 5.7 GO:0031209 SCAR complex(GO:0031209)
0.4 5.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.4 4.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.4 7.8 GO:0005838 proteasome regulatory particle(GO:0005838)
0.4 1.9 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.4 1.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.4 4.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 1.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.3 2.3 GO:0031931 TORC1 complex(GO:0031931)
0.3 1.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 5.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 4.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 5.2 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 3.3 GO:0070578 RISC-loading complex(GO:0070578)
0.2 12.0 GO:0031430 M band(GO:0031430)
0.2 3.0 GO:0005577 fibrinogen complex(GO:0005577)
0.2 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 3.6 GO:0043025 neuronal cell body(GO:0043025)
0.2 5.0 GO:0032040 small-subunit processome(GO:0032040)
0.2 16.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 2.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 2.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 1.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 10.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 10.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.7 GO:0030914 STAGA complex(GO:0030914)
0.2 5.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 4.1 GO:0030673 axolemma(GO:0030673)
0.2 4.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 10.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.8 GO:0030686 90S preribosome(GO:0030686)
0.1 5.9 GO:0001772 immunological synapse(GO:0001772)
0.1 41.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 2.9 GO:0030904 retromer complex(GO:0030904)
0.1 3.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 2.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 2.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 15.9 GO:0001650 fibrillar center(GO:0001650)
0.1 16.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 4.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 5.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 3.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 9.2 GO:0005814 centriole(GO:0005814)
0.1 5.9 GO:0031519 PcG protein complex(GO:0031519)
0.1 13.3 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 2.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.4 GO:0032982 myosin filament(GO:0032982)
0.1 1.0 GO:0098791 Golgi subcompartment(GO:0098791)
0.1 2.1 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 5.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 9.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 7.0 GO:0031902 late endosome membrane(GO:0031902)
0.1 3.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 11.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 23.7 GO:0000790 nuclear chromatin(GO:0000790)
0.1 2.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 3.5 GO:0015935 small ribosomal subunit(GO:0015935) cytosolic small ribosomal subunit(GO:0022627)
0.1 3.9 GO:0030315 T-tubule(GO:0030315)
0.1 14.2 GO:0005769 early endosome(GO:0005769)
0.1 5.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 8.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 3.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 8.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 6.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 5.2 GO:0005795 Golgi stack(GO:0005795)
0.0 1.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 10.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.7 GO:0030496 midbody(GO:0030496)
0.0 7.6 GO:0005925 focal adhesion(GO:0005925)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 5.3 GO:0016604 nuclear body(GO:0016604)
0.0 0.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:0032991 macromolecular complex(GO:0032991)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 9.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
10.8 32.3 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
4.7 18.9 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
3.9 11.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
2.9 11.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
1.9 5.6 GO:0098770 FBXO family protein binding(GO:0098770)
1.8 14.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
1.7 8.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.6 9.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
1.4 4.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.4 5.7 GO:0031493 nucleosomal histone binding(GO:0031493)
1.3 10.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.2 4.9 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
1.2 4.9 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
1.2 4.6 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.1 8.0 GO:0004849 uridine kinase activity(GO:0004849)
1.1 4.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.0 4.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.0 11.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.0 5.0 GO:0004905 type I interferon receptor activity(GO:0004905)
1.0 11.9 GO:0089720 caspase binding(GO:0089720)
0.9 4.7 GO:0002046 opsin binding(GO:0002046)
0.9 10.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.9 20.3 GO:0055103 ligase regulator activity(GO:0055103)
0.9 4.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.9 3.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.8 3.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.8 2.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.7 5.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.7 4.9 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.7 2.0 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.6 4.9 GO:0004111 creatine kinase activity(GO:0004111)
0.6 4.8 GO:0016778 diphosphotransferase activity(GO:0016778)
0.5 6.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.5 1.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.5 13.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.5 5.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.5 10.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 1.7 GO:0005124 scavenger receptor binding(GO:0005124)
0.4 4.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 2.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.4 1.7 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.4 4.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.4 18.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 4.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.4 3.6 GO:0043426 MRF binding(GO:0043426)
0.4 1.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.4 9.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4 8.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 3.8 GO:0031013 troponin I binding(GO:0031013)
0.3 5.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 3.5 GO:0035325 Toll-like receptor binding(GO:0035325)
0.3 1.2 GO:0009881 photoreceptor activity(GO:0009881)
0.3 3.0 GO:0030911 TPR domain binding(GO:0030911)
0.3 7.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 7.9 GO:0030515 snoRNA binding(GO:0030515)
0.3 1.9 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 7.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 3.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 1.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 10.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 3.9 GO:0003680 AT DNA binding(GO:0003680)
0.2 6.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 2.3 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 1.6 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 3.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 10.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 6.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.3 GO:0000339 RNA cap binding(GO:0000339)
0.2 1.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 3.9 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 1.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 3.6 GO:0051400 BH domain binding(GO:0051400)
0.2 4.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 6.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 1.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 8.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 0.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 2.8 GO:0016502 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 5.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 22.7 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 5.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 2.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 3.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 2.6 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.1 5.5 GO:0042287 MHC protein binding(GO:0042287)
0.1 3.0 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0032052 bile acid binding(GO:0032052)
0.1 1.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 2.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 10.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 7.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 26.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 4.9 GO:0070888 E-box binding(GO:0070888)
0.1 2.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 4.2 GO:0019894 kinesin binding(GO:0019894)
0.1 2.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 13.1 GO:0044325 ion channel binding(GO:0044325)
0.1 8.8 GO:0051082 unfolded protein binding(GO:0051082)
0.1 2.5 GO:0001848 complement binding(GO:0001848)
0.1 9.1 GO:0008565 protein transporter activity(GO:0008565)
0.1 3.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 5.7 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 0.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.7 GO:0009055 electron carrier activity(GO:0009055)
0.1 0.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.8 GO:0043022 ribosome binding(GO:0043022)
0.1 3.8 GO:0004601 peroxidase activity(GO:0004601)
0.1 3.6 GO:0070035 ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.1 3.2 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 3.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 4.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 2.9 GO:0019843 rRNA binding(GO:0019843)
0.1 28.5 GO:0019900 kinase binding(GO:0019900)
0.1 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 6.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 2.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 7.0 GO:0051015 actin filament binding(GO:0051015)
0.0 2.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 2.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.7 GO:0005507 copper ion binding(GO:0005507)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.6 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 4.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.1 GO:0017076 purine nucleotide binding(GO:0017076)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 5.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 7.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 4.3 GO:0003924 GTPase activity(GO:0003924)
0.0 2.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 5.0 GO:0005543 phospholipid binding(GO:0005543)
0.0 4.4 GO:0046982 protein heterodimerization activity(GO:0046982)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 30.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.4 17.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 19.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.3 3.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 23.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 9.7 PID MYC PATHWAY C-MYC pathway
0.2 3.4 PID IL23 PATHWAY IL23-mediated signaling events
0.2 6.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 8.1 PID CD40 PATHWAY CD40/CD40L signaling
0.2 7.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 7.3 PID IL3 PATHWAY IL3-mediated signaling events
0.2 9.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 19.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 8.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 4.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 4.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 5.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 5.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 6.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 9.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.8 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 6.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 3.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID P73PATHWAY p73 transcription factor network
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 32.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
1.0 11.3 REACTOME OPSINS Genes involved in Opsins
0.9 18.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.7 20.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.7 5.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.6 9.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.6 15.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 6.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 17.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.4 10.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 11.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.4 52.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.4 4.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 3.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.3 4.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 4.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 8.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 2.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3 4.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 7.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.3 7.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 16.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 3.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 3.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 8.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 4.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 3.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 5.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 3.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 17.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 4.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 12.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 4.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 3.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 2.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 5.2