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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for FOXA3_FOXC2
Z-value: 0.25
Motif logo
Transcription factors associated with FOXA3_FOXC2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
FOXA3
|
ENSG00000170608.2 | forkhead box A3 |
|
FOXC2
|
ENSG00000176692.4 | forkhead box C2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXC2 | hg19_v2_chr16_+_86600857_86600921 | -0.14 | 3.4e-02 | Click! |
Activity profile of FOXA3_FOXC2 motif
Sorted Z-values of FOXA3_FOXC2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_26695013 | 11.45 |
ENST00000555059.2
|
CTB-96E2.2
|
Homeobox protein SEBOX |
| chr17_-_26694979 | 11.37 |
ENST00000438614.1
|
VTN
|
vitronectin |
| chr11_-_116708302 | 10.42 |
ENST00000375320.1
ENST00000359492.2 ENST00000375329.2 ENST00000375323.1 |
APOA1
|
apolipoprotein A-I |
| chr11_+_62186498 | 8.86 |
ENST00000278282.2
|
SCGB1A1
|
secretoglobin, family 1A, member 1 (uteroglobin) |
| chr12_-_92539614 | 8.83 |
ENST00000256015.3
|
BTG1
|
B-cell translocation gene 1, anti-proliferative |
| chr17_-_39684550 | 8.01 |
ENST00000455635.1
ENST00000361566.3 |
KRT19
|
keratin 19 |
| chr10_+_71561649 | 6.61 |
ENST00000398978.3
ENST00000354547.3 ENST00000357811.3 |
COL13A1
|
collagen, type XIII, alpha 1 |
| chr4_-_174256276 | 6.20 |
ENST00000296503.5
|
HMGB2
|
high mobility group box 2 |
| chr14_-_36988882 | 5.94 |
ENST00000498187.2
|
NKX2-1
|
NK2 homeobox 1 |
| chr17_+_72426891 | 5.76 |
ENST00000392627.1
|
GPRC5C
|
G protein-coupled receptor, family C, group 5, member C |
| chr10_+_71561704 | 5.70 |
ENST00000520267.1
|
COL13A1
|
collagen, type XIII, alpha 1 |
| chr7_+_129906660 | 5.51 |
ENST00000222481.4
|
CPA2
|
carboxypeptidase A2 (pancreatic) |
| chr8_+_97597148 | 5.50 |
ENST00000521590.1
|
SDC2
|
syndecan 2 |
| chr6_-_41715128 | 5.27 |
ENST00000356667.4
ENST00000373025.3 ENST00000425343.2 |
PGC
|
progastricsin (pepsinogen C) |
| chr11_-_108464465 | 5.05 |
ENST00000525344.1
|
EXPH5
|
exophilin 5 |
| chr10_+_71561630 | 5.03 |
ENST00000398974.3
ENST00000398971.3 ENST00000398968.3 ENST00000398966.3 ENST00000398964.3 ENST00000398969.3 ENST00000356340.3 ENST00000398972.3 ENST00000398973.3 |
COL13A1
|
collagen, type XIII, alpha 1 |
| chr4_+_74269956 | 4.96 |
ENST00000295897.4
ENST00000415165.2 ENST00000503124.1 ENST00000509063.1 ENST00000401494.3 |
ALB
|
albumin |
| chr7_+_112063192 | 4.37 |
ENST00000005558.4
|
IFRD1
|
interferon-related developmental regulator 1 |
| chr2_+_74120094 | 4.36 |
ENST00000409731.3
ENST00000345517.3 ENST00000409918.1 ENST00000442912.1 ENST00000409624.1 |
ACTG2
|
actin, gamma 2, smooth muscle, enteric |
| chr17_-_19290483 | 4.26 |
ENST00000395592.2
ENST00000299610.4 |
MFAP4
|
microfibrillar-associated protein 4 |
| chr15_+_96869165 | 4.23 |
ENST00000421109.2
|
NR2F2
|
nuclear receptor subfamily 2, group F, member 2 |
| chr1_-_57431679 | 4.14 |
ENST00000371237.4
ENST00000535057.1 ENST00000543257.1 |
C8B
|
complement component 8, beta polypeptide |
| chr7_-_107643674 | 3.83 |
ENST00000222399.6
|
LAMB1
|
laminin, beta 1 |
| chr12_+_96588143 | 3.80 |
ENST00000228741.3
ENST00000547249.1 |
ELK3
|
ELK3, ETS-domain protein (SRF accessory protein 2) |
| chr20_+_31823792 | 3.62 |
ENST00000375413.4
ENST00000354297.4 ENST00000375422.2 |
BPIFA1
|
BPI fold containing family A, member 1 |
| chr12_-_15038779 | 3.53 |
ENST00000228938.5
ENST00000539261.1 |
MGP
|
matrix Gla protein |
| chr7_+_134464414 | 3.52 |
ENST00000361901.2
|
CALD1
|
caldesmon 1 |
| chr5_-_137674000 | 3.45 |
ENST00000510119.1
ENST00000513970.1 |
CDC25C
|
cell division cycle 25C |
| chr10_-_118032697 | 3.42 |
ENST00000439649.3
|
GFRA1
|
GDNF family receptor alpha 1 |
| chr7_+_134576317 | 3.36 |
ENST00000424922.1
ENST00000495522.1 |
CALD1
|
caldesmon 1 |
| chr11_-_108464321 | 3.26 |
ENST00000265843.4
|
EXPH5
|
exophilin 5 |
| chr4_-_72649763 | 3.16 |
ENST00000513476.1
|
GC
|
group-specific component (vitamin D binding protein) |
| chr10_-_118032979 | 3.08 |
ENST00000355422.6
|
GFRA1
|
GDNF family receptor alpha 1 |
| chr2_-_21266935 | 3.00 |
ENST00000233242.1
|
APOB
|
apolipoprotein B |
| chr17_-_26697304 | 2.97 |
ENST00000536498.1
|
VTN
|
vitronectin |
| chr7_+_134464376 | 2.81 |
ENST00000454108.1
ENST00000361675.2 |
CALD1
|
caldesmon 1 |
| chr2_-_192711968 | 2.78 |
ENST00000304141.4
|
SDPR
|
serum deprivation response |
| chr2_-_106054952 | 2.75 |
ENST00000336660.5
ENST00000393352.3 ENST00000607522.1 |
FHL2
|
four and a half LIM domains 2 |
| chr4_-_186456652 | 2.71 |
ENST00000284767.5
ENST00000284770.5 |
PDLIM3
|
PDZ and LIM domain 3 |
| chr4_-_186456766 | 2.69 |
ENST00000284771.6
|
PDLIM3
|
PDZ and LIM domain 3 |
| chr5_+_95998746 | 2.60 |
ENST00000508608.1
|
CAST
|
calpastatin |
| chr11_-_107582775 | 2.59 |
ENST00000305991.2
|
SLN
|
sarcolipin |
| chr3_+_142315225 | 2.58 |
ENST00000457734.2
ENST00000483373.1 ENST00000475296.1 ENST00000495744.1 ENST00000476044.1 ENST00000461644.1 |
PLS1
|
plastin 1 |
| chr22_+_21128167 | 2.53 |
ENST00000215727.5
|
SERPIND1
|
serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| chr5_-_41213607 | 2.51 |
ENST00000337836.5
ENST00000433294.1 |
C6
|
complement component 6 |
| chr14_-_38064198 | 2.47 |
ENST00000250448.2
|
FOXA1
|
forkhead box A1 |
| chr3_+_137717571 | 2.45 |
ENST00000343735.4
|
CLDN18
|
claudin 18 |
| chr14_+_21156915 | 2.42 |
ENST00000397990.4
ENST00000555597.1 |
ANG
RNASE4
|
angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4 |
| chr3_-_168864427 | 2.39 |
ENST00000468789.1
|
MECOM
|
MDS1 and EVI1 complex locus |
| chr10_+_124320156 | 2.27 |
ENST00000338354.3
ENST00000344338.3 ENST00000330163.4 ENST00000368909.3 ENST00000368955.3 ENST00000368956.2 |
DMBT1
|
deleted in malignant brain tumors 1 |
| chr2_-_165424973 | 2.27 |
ENST00000543549.1
|
GRB14
|
growth factor receptor-bound protein 14 |
| chr10_+_71562180 | 2.27 |
ENST00000517713.1
ENST00000522165.1 ENST00000520133.1 |
COL13A1
|
collagen, type XIII, alpha 1 |
| chr7_+_73242490 | 2.26 |
ENST00000431918.1
|
CLDN4
|
claudin 4 |
| chr4_+_147096837 | 2.26 |
ENST00000296581.5
ENST00000502781.1 |
LSM6
|
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| chr10_+_124320195 | 2.24 |
ENST00000359586.6
|
DMBT1
|
deleted in malignant brain tumors 1 |
| chrX_+_9431324 | 2.22 |
ENST00000407597.2
ENST00000424279.1 ENST00000536365.1 ENST00000441088.1 ENST00000380961.1 ENST00000415293.1 |
TBL1X
|
transducin (beta)-like 1X-linked |
| chr2_+_58655461 | 2.21 |
ENST00000429095.1
ENST00000429664.1 ENST00000452840.1 |
AC007092.1
|
long intergenic non-protein coding RNA 1122 |
| chr17_+_72427477 | 2.20 |
ENST00000342648.5
ENST00000481232.1 |
GPRC5C
|
G protein-coupled receptor, family C, group 5, member C |
| chr15_+_80364901 | 2.14 |
ENST00000560228.1
ENST00000559835.1 ENST00000559775.1 ENST00000558688.1 ENST00000560392.1 ENST00000560976.1 ENST00000558272.1 ENST00000558390.1 |
ZFAND6
|
zinc finger, AN1-type domain 6 |
| chr20_+_44519948 | 2.13 |
ENST00000354880.5
ENST00000191018.5 |
CTSA
|
cathepsin A |
| chr11_-_72070206 | 2.13 |
ENST00000544382.1
|
CLPB
|
ClpB caseinolytic peptidase B homolog (E. coli) |
| chr1_+_207277590 | 2.12 |
ENST00000367070.3
|
C4BPA
|
complement component 4 binding protein, alpha |
| chr20_+_9049682 | 2.06 |
ENST00000334005.3
ENST00000378473.3 |
PLCB4
|
phospholipase C, beta 4 |
| chr20_+_44520009 | 2.05 |
ENST00000607482.1
ENST00000372459.2 |
CTSA
|
cathepsin A |
| chr17_-_46688334 | 2.04 |
ENST00000239165.7
|
HOXB7
|
homeobox B7 |
| chr12_-_120765565 | 2.03 |
ENST00000423423.3
ENST00000308366.4 |
PLA2G1B
|
phospholipase A2, group IB (pancreas) |
| chr18_+_47088401 | 2.00 |
ENST00000261292.4
ENST00000427224.2 ENST00000580036.1 |
LIPG
|
lipase, endothelial |
| chr3_+_69985734 | 2.00 |
ENST00000314557.6
ENST00000394351.3 |
MITF
|
microphthalmia-associated transcription factor |
| chr13_+_73629107 | 1.94 |
ENST00000539231.1
|
KLF5
|
Kruppel-like factor 5 (intestinal) |
| chr2_+_128175997 | 1.88 |
ENST00000234071.3
ENST00000429925.1 ENST00000442644.1 ENST00000453608.2 |
PROC
|
protein C (inactivator of coagulation factors Va and VIIIa) |
| chr3_+_148545586 | 1.88 |
ENST00000282957.4
ENST00000468341.1 |
CPB1
|
carboxypeptidase B1 (tissue) |
| chr8_-_23261589 | 1.86 |
ENST00000524168.1
ENST00000523833.2 ENST00000519243.1 ENST00000389131.3 |
LOXL2
|
lysyl oxidase-like 2 |
| chr14_-_36990354 | 1.81 |
ENST00000518149.1
|
NKX2-1
|
NK2 homeobox 1 |
| chr3_-_107941230 | 1.81 |
ENST00000264538.3
|
IFT57
|
intraflagellar transport 57 homolog (Chlamydomonas) |
| chr3_+_137728842 | 1.73 |
ENST00000183605.5
|
CLDN18
|
claudin 18 |
| chr11_-_102401469 | 1.71 |
ENST00000260227.4
|
MMP7
|
matrix metallopeptidase 7 (matrilysin, uterine) |
| chr6_+_161123270 | 1.69 |
ENST00000366924.2
ENST00000308192.9 ENST00000418964.1 |
PLG
|
plasminogen |
| chr3_-_99833333 | 1.66 |
ENST00000354552.3
ENST00000331335.5 ENST00000398326.2 |
FILIP1L
|
filamin A interacting protein 1-like |
| chr7_+_134430212 | 1.62 |
ENST00000436461.2
|
CALD1
|
caldesmon 1 |
| chr9_-_110251836 | 1.61 |
ENST00000374672.4
|
KLF4
|
Kruppel-like factor 4 (gut) |
| chr17_+_7487146 | 1.61 |
ENST00000396501.4
ENST00000584378.1 ENST00000423172.2 ENST00000579445.1 ENST00000585217.1 ENST00000581380.1 |
MPDU1
|
mannose-P-dolichol utilization defect 1 |
| chr7_+_134576151 | 1.60 |
ENST00000393118.2
|
CALD1
|
caldesmon 1 |
| chr1_+_74701062 | 1.60 |
ENST00000326637.3
|
TNNI3K
|
TNNI3 interacting kinase |
| chr6_+_125524785 | 1.59 |
ENST00000392482.2
|
TPD52L1
|
tumor protein D52-like 1 |
| chr10_-_126849068 | 1.59 |
ENST00000494626.2
ENST00000337195.5 |
CTBP2
|
C-terminal binding protein 2 |
| chr1_+_104293028 | 1.59 |
ENST00000370079.3
|
AMY1C
|
amylase, alpha 1C (salivary) |
| chr3_+_141106643 | 1.51 |
ENST00000514251.1
|
ZBTB38
|
zinc finger and BTB domain containing 38 |
| chr14_-_94789663 | 1.49 |
ENST00000557225.1
ENST00000341584.3 |
SERPINA6
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
| chrX_-_20236970 | 1.49 |
ENST00000379548.4
|
RPS6KA3
|
ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| chr4_+_169013666 | 1.49 |
ENST00000359299.3
|
ANXA10
|
annexin A10 |
| chr18_-_25616519 | 1.48 |
ENST00000399380.3
|
CDH2
|
cadherin 2, type 1, N-cadherin (neuronal) |
| chr4_-_140223614 | 1.46 |
ENST00000394223.1
|
NDUFC1
|
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa |
| chr14_-_24664540 | 1.45 |
ENST00000530563.1
ENST00000528895.1 ENST00000528669.1 ENST00000532632.1 |
TM9SF1
|
transmembrane 9 superfamily member 1 |
| chr4_+_146403912 | 1.42 |
ENST00000507367.1
ENST00000394092.2 ENST00000515385.1 |
SMAD1
|
SMAD family member 1 |
| chr7_+_77469439 | 1.42 |
ENST00000450574.1
ENST00000416283.2 ENST00000248550.7 |
PHTF2
|
putative homeodomain transcription factor 2 |
| chr11_-_66112555 | 1.40 |
ENST00000425825.2
ENST00000359957.3 |
BRMS1
|
breast cancer metastasis suppressor 1 |
| chr3_+_155588375 | 1.37 |
ENST00000295920.7
|
GMPS
|
guanine monphosphate synthase |
| chr2_-_188312971 | 1.37 |
ENST00000410068.1
ENST00000447403.1 ENST00000410102.1 |
CALCRL
|
calcitonin receptor-like |
| chr7_+_28452130 | 1.35 |
ENST00000357727.2
|
CREB5
|
cAMP responsive element binding protein 5 |
| chr9_-_70490107 | 1.34 |
ENST00000377395.4
ENST00000429800.2 ENST00000430059.2 ENST00000377384.1 ENST00000382405.3 |
CBWD5
|
COBW domain containing 5 |
| chr10_-_81708854 | 1.33 |
ENST00000372292.3
|
SFTPD
|
surfactant protein D |
| chr7_+_106809406 | 1.32 |
ENST00000468410.1
ENST00000478930.1 ENST00000464009.1 ENST00000222574.4 |
HBP1
|
HMG-box transcription factor 1 |
| chr8_+_21777159 | 1.31 |
ENST00000434536.1
ENST00000252512.9 |
XPO7
|
exportin 7 |
| chr2_+_88047606 | 1.31 |
ENST00000359481.4
|
PLGLB2
|
plasminogen-like B2 |
| chr12_-_102872317 | 1.31 |
ENST00000424202.2
|
IGF1
|
insulin-like growth factor 1 (somatomedin C) |
| chr4_-_103266626 | 1.30 |
ENST00000356736.4
|
SLC39A8
|
solute carrier family 39 (zinc transporter), member 8 |
| chr4_-_70080449 | 1.29 |
ENST00000446444.1
|
UGT2B11
|
UDP glucuronosyltransferase 2 family, polypeptide B11 |
| chr4_-_140223670 | 1.24 |
ENST00000394228.1
ENST00000539387.1 |
NDUFC1
|
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa |
| chr3_-_133969673 | 1.23 |
ENST00000427044.2
|
RYK
|
receptor-like tyrosine kinase |
| chr4_-_186696425 | 1.22 |
ENST00000430503.1
ENST00000319454.6 ENST00000450341.1 |
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr3_-_113897899 | 1.20 |
ENST00000383673.2
ENST00000295881.7 |
DRD3
|
dopamine receptor D3 |
| chr16_+_67381289 | 1.20 |
ENST00000435835.3
|
LRRC36
|
leucine rich repeat containing 36 |
| chr16_+_67381263 | 1.18 |
ENST00000541146.1
ENST00000563189.1 ENST00000290940.7 |
LRRC36
|
leucine rich repeat containing 36 |
| chr17_+_7476136 | 1.18 |
ENST00000582169.1
ENST00000578754.1 ENST00000578495.1 ENST00000293831.8 ENST00000380512.5 ENST00000585024.1 ENST00000583802.1 ENST00000577269.1 ENST00000584784.1 ENST00000582746.1 |
EIF4A1
|
eukaryotic translation initiation factor 4A1 |
| chr10_+_123923105 | 1.17 |
ENST00000368999.1
|
TACC2
|
transforming, acidic coiled-coil containing protein 2 |
| chr6_-_87804815 | 1.16 |
ENST00000369582.2
|
CGA
|
glycoprotein hormones, alpha polypeptide |
| chr15_-_59041768 | 1.16 |
ENST00000402627.1
ENST00000396140.2 ENST00000559053.1 ENST00000561288.1 |
ADAM10
|
ADAM metallopeptidase domain 10 |
| chr1_-_150669500 | 1.15 |
ENST00000271732.3
|
GOLPH3L
|
golgi phosphoprotein 3-like |
| chr1_+_104159999 | 1.13 |
ENST00000414303.2
ENST00000423678.1 |
AMY2A
|
amylase, alpha 2A (pancreatic) |
| chr6_-_49755019 | 1.12 |
ENST00000304801.3
|
PGK2
|
phosphoglycerate kinase 2 |
| chr14_+_51706886 | 1.11 |
ENST00000457354.2
|
TMX1
|
thioredoxin-related transmembrane protein 1 |
| chr4_-_70826725 | 1.10 |
ENST00000353151.3
|
CSN2
|
casein beta |
| chr19_+_41257084 | 1.10 |
ENST00000601393.1
|
SNRPA
|
small nuclear ribonucleoprotein polypeptide A |
| chr3_+_135741576 | 1.09 |
ENST00000334546.2
|
PPP2R3A
|
protein phosphatase 2, regulatory subunit B'', alpha |
| chr1_+_151739131 | 1.08 |
ENST00000400999.1
|
OAZ3
|
ornithine decarboxylase antizyme 3 |
| chr17_-_202579 | 1.07 |
ENST00000577079.1
ENST00000331302.7 ENST00000536489.2 |
RPH3AL
|
rabphilin 3A-like (without C2 domains) |
| chr1_-_43855444 | 1.06 |
ENST00000372455.4
|
MED8
|
mediator complex subunit 8 |
| chr10_-_126849588 | 1.05 |
ENST00000411419.2
|
CTBP2
|
C-terminal binding protein 2 |
| chr17_-_39041479 | 1.04 |
ENST00000167588.3
|
KRT20
|
keratin 20 |
| chr8_-_6420930 | 1.04 |
ENST00000325203.5
|
ANGPT2
|
angiopoietin 2 |
| chr21_-_43786634 | 1.00 |
ENST00000291527.2
|
TFF1
|
trefoil factor 1 |
| chr20_+_45338126 | 0.99 |
ENST00000359271.2
|
SLC2A10
|
solute carrier family 2 (facilitated glucose transporter), member 10 |
| chr7_-_25268104 | 0.98 |
ENST00000222674.2
|
NPVF
|
neuropeptide VF precursor |
| chr3_-_114343039 | 0.98 |
ENST00000481632.1
|
ZBTB20
|
zinc finger and BTB domain containing 20 |
| chr8_-_95449155 | 0.97 |
ENST00000481490.2
|
FSBP
|
fibrinogen silencer binding protein |
| chr17_+_8924837 | 0.97 |
ENST00000173229.2
|
NTN1
|
netrin 1 |
| chr5_+_179921344 | 0.96 |
ENST00000261951.4
|
CNOT6
|
CCR4-NOT transcription complex, subunit 6 |
| chr2_+_109223595 | 0.95 |
ENST00000410093.1
|
LIMS1
|
LIM and senescent cell antigen-like domains 1 |
| chr8_+_19171128 | 0.94 |
ENST00000265807.3
|
SH2D4A
|
SH2 domain containing 4A |
| chr5_+_179921430 | 0.94 |
ENST00000393356.1
|
CNOT6
|
CCR4-NOT transcription complex, subunit 6 |
| chr9_-_75567962 | 0.90 |
ENST00000297785.3
ENST00000376939.1 |
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1 |
| chr12_-_21927736 | 0.89 |
ENST00000240662.2
|
KCNJ8
|
potassium inwardly-rectifying channel, subfamily J, member 8 |
| chr1_+_172389821 | 0.87 |
ENST00000367727.4
|
C1orf105
|
chromosome 1 open reading frame 105 |
| chr7_+_106505696 | 0.86 |
ENST00000440650.2
ENST00000496166.1 ENST00000473541.1 |
PIK3CG
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
| chr1_+_18958008 | 0.82 |
ENST00000420770.2
ENST00000400661.3 |
PAX7
|
paired box 7 |
| chr15_-_40600111 | 0.82 |
ENST00000543785.2
ENST00000260402.3 |
PLCB2
|
phospholipase C, beta 2 |
| chr12_+_58087901 | 0.80 |
ENST00000315970.7
ENST00000547079.1 ENST00000439210.2 ENST00000389146.6 ENST00000413095.2 ENST00000551035.1 ENST00000257966.8 ENST00000435406.2 ENST00000550372.1 ENST00000389142.5 |
OS9
|
osteosarcoma amplified 9, endoplasmic reticulum lectin |
| chr6_-_112575912 | 0.80 |
ENST00000522006.1
ENST00000230538.7 ENST00000519932.1 |
LAMA4
|
laminin, alpha 4 |
| chr21_-_38445011 | 0.79 |
ENST00000464265.1
ENST00000399102.1 |
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chr1_-_54405773 | 0.79 |
ENST00000371376.1
|
HSPB11
|
heat shock protein family B (small), member 11 |
| chr12_+_21525818 | 0.78 |
ENST00000240652.3
ENST00000542023.1 ENST00000537593.1 |
IAPP
|
islet amyloid polypeptide |
| chr3_-_196910721 | 0.77 |
ENST00000443183.1
|
DLG1
|
discs, large homolog 1 (Drosophila) |
| chr7_+_134832808 | 0.77 |
ENST00000275767.3
|
TMEM140
|
transmembrane protein 140 |
| chr12_-_48099754 | 0.77 |
ENST00000380650.4
|
RPAP3
|
RNA polymerase II associated protein 3 |
| chr5_+_101569696 | 0.77 |
ENST00000597120.1
|
AC008948.1
|
AC008948.1 |
| chr10_+_105314881 | 0.76 |
ENST00000437579.1
|
NEURL
|
neuralized E3 ubiquitin protein ligase 1 |
| chr7_+_106505912 | 0.76 |
ENST00000359195.3
|
PIK3CG
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
| chr12_-_48099773 | 0.75 |
ENST00000432584.3
ENST00000005386.3 |
RPAP3
|
RNA polymerase II associated protein 3 |
| chr14_-_25479811 | 0.75 |
ENST00000550887.1
|
STXBP6
|
syntaxin binding protein 6 (amisyn) |
| chr4_-_123377880 | 0.72 |
ENST00000226730.4
|
IL2
|
interleukin 2 |
| chr2_-_182545603 | 0.72 |
ENST00000295108.3
|
NEUROD1
|
neuronal differentiation 1 |
| chr19_-_15443318 | 0.71 |
ENST00000360016.5
|
BRD4
|
bromodomain containing 4 |
| chr12_+_59989918 | 0.70 |
ENST00000547379.1
ENST00000549465.1 |
SLC16A7
|
solute carrier family 16 (monocarboxylate transporter), member 7 |
| chr14_+_58711539 | 0.70 |
ENST00000216455.4
ENST00000412908.2 ENST00000557508.1 |
PSMA3
|
proteasome (prosome, macropain) subunit, alpha type, 3 |
| chr1_-_246357029 | 0.69 |
ENST00000391836.2
|
SMYD3
|
SET and MYND domain containing 3 |
| chr1_-_246729544 | 0.69 |
ENST00000544618.1
ENST00000366514.4 |
TFB2M
|
transcription factor B2, mitochondrial |
| chr1_+_154540246 | 0.69 |
ENST00000368476.3
|
CHRNB2
|
cholinergic receptor, nicotinic, beta 2 (neuronal) |
| chr6_-_161085291 | 0.68 |
ENST00000316300.5
|
LPA
|
lipoprotein, Lp(a) |
| chr9_-_14722715 | 0.68 |
ENST00000380911.3
|
CER1
|
cerberus 1, DAN family BMP antagonist |
| chr1_-_169555779 | 0.67 |
ENST00000367797.3
ENST00000367796.3 |
F5
|
coagulation factor V (proaccelerin, labile factor) |
| chr18_-_3874271 | 0.67 |
ENST00000400149.3
ENST00000400155.1 ENST00000400150.3 |
DLGAP1
|
discs, large (Drosophila) homolog-associated protein 1 |
| chr14_+_74034310 | 0.67 |
ENST00000538782.1
|
ACOT2
|
acyl-CoA thioesterase 2 |
| chr19_+_47421933 | 0.65 |
ENST00000404338.3
|
ARHGAP35
|
Rho GTPase activating protein 35 |
| chr12_-_18243075 | 0.64 |
ENST00000536890.1
|
RERGL
|
RERG/RAS-like |
| chr1_-_146696901 | 0.64 |
ENST00000369272.3
ENST00000441068.2 |
FMO5
|
flavin containing monooxygenase 5 |
| chr12_-_102591604 | 0.64 |
ENST00000329406.4
|
PMCH
|
pro-melanin-concentrating hormone |
| chr18_-_52626622 | 0.62 |
ENST00000591504.1
|
CCDC68
|
coiled-coil domain containing 68 |
| chrX_+_99839799 | 0.61 |
ENST00000373031.4
|
TNMD
|
tenomodulin |
| chr7_-_81399438 | 0.61 |
ENST00000222390.5
|
HGF
|
hepatocyte growth factor (hepapoietin A; scatter factor) |
| chr6_-_26056695 | 0.61 |
ENST00000343677.2
|
HIST1H1C
|
histone cluster 1, H1c |
| chr4_+_118955500 | 0.60 |
ENST00000296499.5
|
NDST3
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 |
| chr18_-_3874247 | 0.58 |
ENST00000581699.1
|
DLGAP1
|
discs, large (Drosophila) homolog-associated protein 1 |
| chr1_+_152486950 | 0.57 |
ENST00000368790.3
|
CRCT1
|
cysteine-rich C-terminal 1 |
| chr10_+_35484053 | 0.57 |
ENST00000487763.1
ENST00000473940.1 ENST00000488328.1 ENST00000356917.5 |
CREM
|
cAMP responsive element modulator |
| chr1_-_28384598 | 0.56 |
ENST00000373864.1
|
EYA3
|
eyes absent homolog 3 (Drosophila) |
| chr1_+_86934526 | 0.55 |
ENST00000394711.1
|
CLCA1
|
chloride channel accessory 1 |
| chr5_-_98262240 | 0.55 |
ENST00000284049.3
|
CHD1
|
chromodomain helicase DNA binding protein 1 |
| chr3_+_148447887 | 0.55 |
ENST00000475347.1
ENST00000474935.1 ENST00000461609.1 |
AGTR1
|
angiotensin II receptor, type 1 |
| chr20_-_7921090 | 0.54 |
ENST00000378789.3
|
HAO1
|
hydroxyacid oxidase (glycolate oxidase) 1 |
| chrX_+_24167746 | 0.54 |
ENST00000428571.1
ENST00000539115.1 |
ZFX
|
zinc finger protein, X-linked |
| chr15_-_59665062 | 0.53 |
ENST00000288235.4
|
MYO1E
|
myosin IE |
| chr1_+_18957500 | 0.53 |
ENST00000375375.3
|
PAX7
|
paired box 7 |
| chr9_+_70856397 | 0.52 |
ENST00000360171.6
|
CBWD3
|
COBW domain containing 3 |
| chr6_-_25830785 | 0.52 |
ENST00000468082.1
|
SLC17A1
|
solute carrier family 17 (organic anion transporter), member 1 |
| chr2_+_28974668 | 0.52 |
ENST00000296122.6
ENST00000395366.2 |
PPP1CB
|
protein phosphatase 1, catalytic subunit, beta isozyme |
| chr3_+_136649311 | 0.51 |
ENST00000469404.1
ENST00000467911.1 |
NCK1
|
NCK adaptor protein 1 |
| chr18_-_3874752 | 0.51 |
ENST00000534970.1
|
DLGAP1
|
discs, large (Drosophila) homolog-associated protein 1 |
| chr11_+_7110165 | 0.50 |
ENST00000306904.5
|
RBMXL2
|
RNA binding motif protein, X-linked-like 2 |
| chr7_-_81399355 | 0.50 |
ENST00000457544.2
|
HGF
|
hepatocyte growth factor (hepapoietin A; scatter factor) |
| chr15_-_66797172 | 0.50 |
ENST00000569438.1
ENST00000569696.1 ENST00000307961.6 |
RPL4
|
ribosomal protein L4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXA3_FOXC2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 10.4 | GO:0010903 | negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) |
| 1.7 | 5.0 | GO:0044179 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 1.6 | 14.3 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 1.6 | 7.8 | GO:0021759 | globus pallidus development(GO:0021759) |
| 1.5 | 8.9 | GO:0010193 | response to ozone(GO:0010193) |
| 1.5 | 4.4 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 1.1 | 8.0 | GO:0008218 | bioluminescence(GO:0008218) |
| 1.1 | 4.2 | GO:0009956 | radial pattern formation(GO:0009956) |
| 1.0 | 2.0 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
| 1.0 | 3.8 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.9 | 3.6 | GO:0042710 | biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) |
| 0.9 | 5.3 | GO:0002803 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
| 0.9 | 2.6 | GO:1901877 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 0.7 | 4.4 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.7 | 8.8 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.6 | 4.5 | GO:0032431 | activation of phospholipase A2 activity(GO:0032431) |
| 0.6 | 2.5 | GO:0001970 | positive regulation of activation of membrane attack complex(GO:0001970) |
| 0.6 | 1.9 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
| 0.6 | 6.2 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.6 | 2.5 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.6 | 0.6 | GO:0035992 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.6 | 6.5 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.6 | 5.8 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.6 | 1.7 | GO:2000048 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.6 | 2.8 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.5 | 1.6 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 0.5 | 1.6 | GO:0071409 | negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409) |
| 0.5 | 0.5 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 0.5 | 2.6 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.5 | 4.2 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 0.5 | 8.3 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.4 | 3.0 | GO:0006642 | triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269) |
| 0.4 | 4.2 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 0.4 | 1.2 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.4 | 1.5 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.4 | 19.6 | GO:0001958 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.4 | 1.1 | GO:1903487 | regulation of lactation(GO:1903487) |
| 0.4 | 4.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.3 | 1.3 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.3 | 1.9 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.3 | 1.2 | GO:0061643 | chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643) |
| 0.3 | 0.9 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.3 | 1.2 | GO:0050883 | negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.3 | 1.5 | GO:2000809 | positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.3 | 2.6 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.3 | 5.5 | GO:0007039 | protein catabolic process in the vacuole(GO:0007039) |
| 0.3 | 1.3 | GO:1904073 | trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 0.3 | 1.0 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 0.2 | 3.3 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.2 | 2.1 | GO:0045959 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027) |
| 0.2 | 1.4 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.2 | 4.1 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.2 | 1.9 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.2 | 1.1 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.2 | 8.0 | GO:0060706 | cell differentiation involved in embryonic placenta development(GO:0060706) |
| 0.2 | 1.0 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.2 | 0.5 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) |
| 0.2 | 0.7 | GO:2000317 | regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
| 0.2 | 0.5 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 0.2 | 0.7 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.2 | 0.7 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) synaptic transmission involved in micturition(GO:0060084) |
| 0.2 | 0.5 | GO:1903676 | regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676) |
| 0.2 | 0.7 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.2 | 1.1 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.2 | 0.5 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.1 | 3.5 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.1 | 1.4 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.1 | 1.1 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.1 | 0.7 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.1 | 1.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.1 | 1.4 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.1 | 0.5 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.1 | 2.6 | GO:0060972 | left/right pattern formation(GO:0060972) |
| 0.1 | 3.2 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.1 | 0.4 | GO:0034146 | toll-like receptor 5 signaling pathway(GO:0034146) |
| 0.1 | 4.2 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
| 0.1 | 0.8 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.1 | 1.0 | GO:0030202 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.1 | 0.6 | GO:0015722 | canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823) |
| 0.1 | 0.9 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
| 0.1 | 0.8 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) |
| 0.1 | 0.6 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.1 | 1.6 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.1 | 0.3 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.1 | 0.7 | GO:1901475 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.1 | 0.4 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.1 | 0.8 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.1 | 2.1 | GO:0072663 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.1 | 2.0 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.1 | 0.8 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.1 | 0.8 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.1 | 1.9 | GO:0032332 | positive regulation of chondrocyte differentiation(GO:0032332) |
| 0.1 | 2.4 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.1 | 1.5 | GO:0006914 | autophagy(GO:0006914) |
| 0.1 | 0.6 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.1 | 1.7 | GO:0044849 | estrous cycle(GO:0044849) |
| 0.1 | 1.6 | GO:0086069 | bundle of His cell to Purkinje myocyte communication(GO:0086069) |
| 0.1 | 1.5 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.1 | 2.3 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.1 | 0.9 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 0.9 | GO:0098915 | membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) |
| 0.1 | 1.5 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
| 0.1 | 1.5 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 1.0 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.1 | 0.1 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.1 | 0.2 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 0.5 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.1 | 2.3 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.1 | 0.3 | GO:1903301 | fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.0 | 0.7 | GO:0034374 | low-density lipoprotein particle remodeling(GO:0034374) |
| 0.0 | 1.1 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 0.0 | 0.2 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.0 | 1.2 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.7 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.0 | 2.2 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 2.7 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.3 | GO:0032277 | negative regulation of gonadotropin secretion(GO:0032277) |
| 0.0 | 0.8 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.0 | 0.4 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546) |
| 0.0 | 0.2 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.0 | 0.8 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.0 | 0.6 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.1 | GO:0002215 | defense response to nematode(GO:0002215) |
| 0.0 | 0.1 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.0 | 1.0 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.1 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 0.0 | 0.9 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 0.0 | 0.3 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.0 | 0.6 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 1.3 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.0 | 0.3 | GO:0002689 | negative regulation of leukocyte chemotaxis(GO:0002689) gamma-delta T cell differentiation(GO:0042492) |
| 0.0 | 0.6 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.0 | 0.7 | GO:0014904 | myotube cell development(GO:0014904) |
| 0.0 | 0.6 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.0 | 1.2 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.0 | 0.2 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
| 0.0 | 1.0 | GO:0035902 | response to immobilization stress(GO:0035902) |
| 0.0 | 11.7 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.0 | 0.7 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.0 | 1.2 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.7 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 2.2 | GO:0016575 | histone deacetylation(GO:0016575) |
| 0.0 | 1.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 0.1 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
| 0.0 | 1.1 | GO:0030317 | sperm motility(GO:0030317) |
| 0.0 | 0.1 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 0.0 | 0.4 | GO:0045577 | regulation of B cell differentiation(GO:0045577) |
| 0.0 | 1.3 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.0 | 0.3 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.0 | 0.4 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.0 | 0.6 | GO:0046850 | regulation of bone remodeling(GO:0046850) |
| 0.0 | 1.2 | GO:0017158 | regulation of calcium ion-dependent exocytosis(GO:0017158) |
| 0.0 | 1.1 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 0.1 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.0 | 0.6 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 0.3 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.9 | 19.6 | GO:0005600 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 3.6 | 14.3 | GO:0071062 | rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 3.5 | 10.4 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 1.8 | 10.6 | GO:1990357 | terminal web(GO:1990357) |
| 1.3 | 3.8 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 0.9 | 12.9 | GO:0030478 | actin cap(GO:0030478) |
| 0.7 | 6.6 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.6 | 4.2 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.5 | 1.6 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 0.5 | 3.0 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.4 | 4.3 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.4 | 2.4 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.3 | 5.1 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.3 | 0.9 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
| 0.3 | 0.9 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.3 | 2.6 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.3 | 1.7 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.3 | 1.3 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.2 | 2.3 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.2 | 4.4 | GO:0032982 | myosin filament(GO:0032982) |
| 0.2 | 0.8 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.2 | 1.5 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.2 | 1.8 | GO:0044292 | dendrite terminus(GO:0044292) |
| 0.1 | 1.5 | GO:0016342 | catenin complex(GO:0016342) |
| 0.1 | 1.2 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 1.9 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 1.1 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 9.4 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 0.9 | GO:0042587 | glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 0.8 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 6.3 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 1.3 | GO:0042599 | lamellar body(GO:0042599) |
| 0.1 | 1.5 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 8.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 2.1 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 0.8 | GO:0097025 | lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.1 | 2.8 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 2.2 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 12.8 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 2.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 0.7 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.1 | 1.5 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 1.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 1.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 6.6 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 1.5 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.5 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 6.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 2.7 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 2.8 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.4 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.0 | 4.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 1.1 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 2.5 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.8 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 1.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.7 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.8 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 1.2 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 6.4 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.0 | 0.1 | GO:0001652 | granular component(GO:0001652) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.3 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 0.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 23.2 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 1.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 1.0 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 0.1 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 1.3 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.7 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.5 | GO:0000786 | nucleosome(GO:0000786) DNA packaging complex(GO:0044815) |
| 0.0 | 4.9 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.3 | GO:0061695 | transferase complex, transferring phosphorus-containing groups(GO:0061695) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 10.4 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 1.6 | 6.2 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 1.5 | 8.9 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 1.3 | 4.0 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.9 | 6.5 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.7 | 3.0 | GO:0035473 | lipase binding(GO:0035473) |
| 0.6 | 10.0 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.6 | 8.4 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.5 | 3.2 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.5 | 4.2 | GO:0016997 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
| 0.5 | 12.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.4 | 2.6 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.4 | 2.4 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.4 | 2.6 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.4 | 1.1 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 0.3 | 1.4 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.3 | 1.6 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.3 | 1.6 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.3 | 5.0 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.3 | 0.9 | GO:0017098 | sulfonylurea receptor binding(GO:0017098) |
| 0.3 | 1.1 | GO:0016160 | amylase activity(GO:0016160) |
| 0.3 | 2.0 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.2 | 7.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.2 | 5.3 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.2 | 0.7 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 0.2 | 1.6 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.2 | 1.1 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.2 | 1.7 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.2 | 1.2 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.2 | 0.6 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 0.2 | 2.0 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.2 | 0.5 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 0.2 | 0.9 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.2 | 0.5 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
| 0.2 | 0.7 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.2 | 1.2 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.2 | 1.0 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.2 | 1.9 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.2 | 4.5 | GO:0038187 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.2 | 1.1 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.1 | 0.7 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.1 | 0.9 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.1 | 0.6 | GO:0015265 | glycerol channel activity(GO:0015254) urea channel activity(GO:0015265) |
| 0.1 | 13.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 0.7 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.1 | 0.6 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.1 | 0.5 | GO:0047708 | biotinidase activity(GO:0047708) |
| 0.1 | 23.8 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 1.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 1.5 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 4.2 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 0.8 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 0.1 | 1.5 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 0.3 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.1 | 1.1 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 1.9 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 0.5 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 3.0 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 1.4 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.1 | 0.7 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.1 | 8.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.3 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 0.1 | 0.4 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.1 | 0.3 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 0.8 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 3.5 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 1.0 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.1 | 0.6 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 0.8 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 1.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 1.3 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.1 | 0.5 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.1 | 1.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 0.7 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 0.3 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 1.2 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.1 | 1.1 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.1 | 2.1 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.1 | 1.4 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.1 | 2.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 2.4 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 0.7 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.3 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.0 | 0.3 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.0 | 0.8 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.8 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 2.8 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 1.3 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 1.3 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.6 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.0 | 2.6 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 1.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 3.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.7 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 2.7 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 4.5 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.7 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 2.4 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 3.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.1 | GO:0089720 | caspase binding(GO:0089720) |
| 0.0 | 0.9 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 0.1 | GO:1990404 | protein ADP-ribosylase activity(GO:1990404) |
| 0.0 | 1.2 | GO:0035257 | nuclear hormone receptor binding(GO:0035257) |
| 0.0 | 0.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.2 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.0 | 11.6 | GO:0003712 | transcription cofactor activity(GO:0003712) |
| 0.0 | 1.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 5.9 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 0.3 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 2.2 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.5 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.0 | 0.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 1.1 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.0 | 0.8 | GO:0001540 | beta-amyloid binding(GO:0001540) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 15.2 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.4 | 19.6 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.3 | 25.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.3 | 18.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.2 | 11.7 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.2 | 6.3 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 9.3 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 5.5 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 3.2 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 1.1 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 1.1 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 4.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 6.1 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 2.8 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 1.6 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.1 | 0.5 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 0.6 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.1 | 4.3 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 3.5 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 2.8 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.1 | 2.6 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 1.3 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.0 | 0.9 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 10.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 1.3 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.7 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.8 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 5.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.4 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 0.7 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 1.9 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.2 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.3 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.9 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.1 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 0.8 | PID CDC42 PATHWAY | CDC42 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 15.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.3 | 6.8 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.3 | 19.6 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.3 | 3.7 | REACTOME LIPOPROTEIN METABOLISM | Genes involved in Lipoprotein metabolism |
| 0.3 | 16.2 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 2.7 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.2 | 5.5 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.2 | 3.5 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.2 | 8.8 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.2 | 2.6 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.2 | 19.5 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.2 | 5.7 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.2 | 6.5 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.2 | 2.3 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.1 | 2.0 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 3.3 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 4.3 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 0.9 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 1.2 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.1 | 10.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 4.2 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 3.1 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 3.3 | REACTOME EXTRACELLULAR MATRIX ORGANIZATION | Genes involved in Extracellular matrix organization |
| 0.1 | 1.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 1.4 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 2.3 | REACTOME G PROTEIN BETA GAMMA SIGNALLING | Genes involved in G-protein beta:gamma signalling |
| 0.1 | 1.5 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 1.5 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 2.2 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 1.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 1.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.7 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 1.5 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.0 | 0.7 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.6 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.9 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.7 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.5 | REACTOME REGULATION OF APOPTOSIS | Genes involved in Regulation of Apoptosis |
| 0.0 | 2.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 0.9 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.0 | 1.0 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.5 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 1.2 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.9 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.5 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 1.8 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 2.7 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 0.2 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.6 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 1.2 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 1.1 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 0.8 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 2.9 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.0 | 0.9 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.7 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.2 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |