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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 0.94

Motif logo

Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Gene Symbol Gene ID Gene Info
ENSG00000251493.2 forkhead box D1
ENSG00000150907.6 forkhead box O1
ENSG00000204060.4 forkhead box O6
ENSG00000176165.7 forkhead box G1
ENSG00000114861.14 forkhead box P1

Activity-expression correlation:

Activity profile of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Sorted Z-values of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_145438469 55.45 ENST00000369317.4
thioredoxin interacting protein
chr11_+_117049854 54.35 ENST00000278951.7
SID1 transmembrane family, member 2
chr12_-_92539614 53.24 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr11_+_117049445 41.16 ENST00000324225.4
ENST00000532960.1
SID1 transmembrane family, member 2
chr13_-_46716969 39.76 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_106960285 39.37 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr11_+_117049910 35.73 ENST00000431081.2
ENST00000524842.1
SID1 transmembrane family, member 2
chr6_+_89791507 34.56 ENST00000354922.3
proline-rich nuclear receptor coactivator 1
chr19_+_12902289 33.77 ENST00000302754.4
jun B proto-oncogene
chr6_-_31550192 28.14 ENST00000429299.2
ENST00000446745.2
lymphotoxin beta (TNF superfamily, member 3)
chr5_-_42812143 26.93 ENST00000514985.1
selenoprotein P, plasma, 1
chr5_-_42811986 25.76 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr7_+_106809406 24.91 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HMG-box transcription factor 1
chr19_-_58609570 24.47 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
zinc finger and SCAN domain containing 18
chr13_-_41240717 22.63 ENST00000379561.5
forkhead box O1
chr7_-_37026108 22.41 ENST00000396045.3
engulfment and cell motility 1
chr17_-_42580738 21.81 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
G patch domain containing 8
chr22_-_31688431 21.49 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
phosphoinositide-3-kinase interacting protein 1
chr18_-_53257027 21.43 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
transcription factor 4
chr19_-_39826639 20.89 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chr14_-_23288930 20.82 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_-_42016385 19.63 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
cyclin D3
chr17_-_40897043 19.30 ENST00000428826.2
ENST00000592492.1
ENST00000585893.1
ENST00000593214.1
ENST00000590078.1
ENST00000586382.1
ENST00000415827.2
ENST00000592743.1
ENST00000586089.1
ENST00000435174.1
enhancer of zeste homolog 1 (Drosophila)
chr10_+_104535994 18.98 ENST00000369889.4
WW domain binding protein 1-like
chr1_+_84630645 18.86 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_29641104 18.58 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr3_-_18466026 18.21 ENST00000417717.2
SATB homeobox 1
chr5_-_169725231 18.08 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_72504637 18.05 ENST00000536377.1
ENST00000359373.5
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_+_16435625 16.70 ENST00000248071.5
ENST00000592003.1
Kruppel-like factor 2
chr17_-_29641084 16.64 ENST00000544462.1
ecotropic viral integration site 2B
chr5_+_176853702 15.83 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
G protein-coupled receptor kinase 6
chr2_-_160472952 15.55 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
bromodomain adjacent to zinc finger domain, 2B
chr18_-_53070913 15.02 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr10_+_111985713 14.81 ENST00000239007.7
MAX interactor 1, dimerization protein
chr19_+_50380917 14.77 ENST00000535102.2
TBC1 domain family, member 17
chr15_-_60884706 14.74 ENST00000449337.2
RAR-related orphan receptor A
chr22_-_31688381 14.42 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr15_+_81589254 14.27 ENST00000394652.2
interleukin 16
chr19_+_50380682 14.11 ENST00000221543.5
TBC1 domain family, member 17
chr14_+_24583836 13.97 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr6_+_139094657 13.92 ENST00000332797.6
coiled-coil domain containing 28A
chr5_+_176853669 13.84 ENST00000355472.5
G protein-coupled receptor kinase 6
chr10_+_99079008 13.76 ENST00000371021.3
frequently rearranged in advanced T-cell lymphomas
chr11_+_13299186 13.62 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
aryl hydrocarbon receptor nuclear translocator-like
chr14_+_24584508 13.47 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DDB1 and CUL4 associated factor 11
chr5_-_131132658 12.49 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr19_+_1205740 12.42 ENST00000326873.7
serine/threonine kinase 11
chr2_+_12857043 12.36 ENST00000381465.2
tribbles pseudokinase 2
chr3_-_114477787 12.31 ENST00000464560.1
zinc finger and BTB domain containing 20
chr2_+_97481974 12.26 ENST00000377060.3
ENST00000305510.3
cyclin M3
chrX_-_48937503 12.10 ENST00000322995.8
WD repeat domain 45
chr6_+_6588902 12.03 ENST00000230568.4
lymphocyte antigen 86
chr3_-_3221358 11.93 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr2_+_12857015 11.70 ENST00000155926.4
tribbles pseudokinase 2
chr1_-_207095324 11.66 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr13_-_46756351 11.47 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr18_-_53303123 11.23 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
transcription factor 4
chr19_-_18391708 11.22 ENST00000600972.1
jun D proto-oncogene
chr17_-_26662440 11.20 ENST00000578122.1
intraflagellar transport 20 homolog (Chlamydomonas)
chr1_-_65432171 10.96 ENST00000342505.4
Janus kinase 1
chr10_-_99094458 10.95 ENST00000371019.2
frequently rearranged in advanced T-cell lymphomas 2
chr17_-_26662464 10.74 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
intraflagellar transport 20 homolog (Chlamydomonas)
chr1_+_227127981 10.67 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
aarF domain containing kinase 3
chrX_-_48937531 10.50 ENST00000473974.1
ENST00000475880.1
ENST00000396681.4
ENST00000553851.1
ENST00000471338.1
ENST00000476728.1
ENST00000376368.2
ENST00000485908.1
ENST00000376372.3
ENST00000376358.3
WD repeat domain 45
WD repeat domain phosphoinositide-interacting protein 4
chr8_+_95908041 10.32 ENST00000396113.1
ENST00000519136.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr6_-_87804815 9.90 ENST00000369582.2
glycoprotein hormones, alpha polypeptide
chr12_+_12764773 9.62 ENST00000228865.2
cAMP responsive element binding protein-like 2
chr14_-_74551096 9.52 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr12_+_50135327 9.49 ENST00000549966.1
ENST00000547832.1
ENST00000547187.1
ENST00000548894.1
ENST00000546914.1
ENST00000552699.1
ENST00000267115.5
transmembrane BAX inhibitor motif containing 6
chr5_-_142782862 9.39 ENST00000415690.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr11_+_10476851 9.24 ENST00000396553.2
adenosine monophosphate deaminase 3
chr14_-_21493649 9.22 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr9_-_135819987 9.05 ENST00000298552.3
ENST00000403810.1
tuberous sclerosis 1
chr7_+_134832808 9.01 ENST00000275767.3
transmembrane protein 140
chr2_-_71454185 9.00 ENST00000244221.8
poly(A) binding protein interacting protein 2B
chr9_-_84303269 8.82 ENST00000418319.1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr12_+_50135351 8.68 ENST00000549445.1
ENST00000550951.1
ENST00000549385.1
ENST00000548713.1
ENST00000548201.1
transmembrane BAX inhibitor motif containing 6
chr14_-_21493884 8.54 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG family member 2
chr12_-_9268707 8.53 ENST00000318602.7
alpha-2-macroglobulin
chr20_-_43150601 8.48 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr12_+_50135588 8.34 ENST00000423828.1
ENST00000550445.1
transmembrane BAX inhibitor motif containing 6
chr1_-_207095212 8.29 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr2_+_74120094 8.17 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
actin, gamma 2, smooth muscle, enteric
chr15_-_40600026 8.10 ENST00000456256.2
ENST00000557821.1
phospholipase C, beta 2
chr12_-_91574142 8.05 ENST00000547937.1
decorin
chr10_-_90751038 7.99 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr5_+_169064245 7.98 ENST00000256935.8
dedicator of cytokinesis 2
chr14_-_21493123 7.92 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr13_-_67802549 7.79 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr3_-_114477962 7.70 ENST00000471418.1
zinc finger and BTB domain containing 20
chr18_+_9475585 7.64 ENST00000585015.1
ralA binding protein 1
chr10_-_45474237 7.61 ENST00000448778.1
ENST00000298295.3
chromosome 10 open reading frame 10
chr9_+_2159850 7.59 ENST00000416751.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr16_+_69958887 7.52 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr22_-_38902300 7.48 ENST00000403230.1
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr1_+_87797351 7.48 ENST00000370542.1
LIM domain only 4
chr15_+_81475047 7.41 ENST00000559388.1
interleukin 16
chr4_-_186456652 7.29 ENST00000284767.5
ENST00000284770.5
PDZ and LIM domain 3
chr14_-_91526922 7.27 ENST00000418736.2
ENST00000261991.3
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr1_-_12677714 7.24 ENST00000376223.2
dehydrogenase/reductase (SDR family) member 3
chr2_-_158345462 7.21 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr1_+_90460661 7.20 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
zinc finger protein 326
chr7_+_91570165 7.00 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
A kinase (PRKA) anchor protein 9
chr10_-_73848086 6.92 ENST00000536168.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr4_-_69215699 6.84 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTH domain containing 1
chr18_-_53177984 6.70 ENST00000543082.1
transcription factor 4
chr9_-_136933134 6.61 ENST00000303407.7
bromodomain containing 3
chr4_-_69215467 6.57 ENST00000579690.1
YTH domain containing 1
chrX_+_135251783 6.55 ENST00000394153.2
four and a half LIM domains 1
chr16_-_84150492 6.48 ENST00000343411.3
membrane-bound transcription factor peptidase, site 1
chr13_-_36920420 6.32 ENST00000438666.2
spastic paraplegia 20 (Troyer syndrome)
chr16_+_4896659 6.24 ENST00000592120.1
ubinuclein 1
chr22_-_38902325 6.16 ENST00000396821.3
ENST00000381633.3
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr1_+_111682058 6.09 ENST00000545121.1
choline/ethanolamine phosphotransferase 1
chr1_+_84630053 5.97 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chrX_+_9431324 5.96 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr12_-_123201337 5.96 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr7_+_80231466 5.91 ENST00000309881.7
ENST00000534394.1
CD36 molecule (thrombospondin receptor)
chr14_-_24584138 5.89 ENST00000558280.1
ENST00000561028.1
neural retina leucine zipper
chr20_+_62887081 5.89 ENST00000369758.4
ENST00000299468.7
ENST00000609372.1
ENST00000610196.1
ENST00000308824.6
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr17_-_26694979 5.78 ENST00000438614.1
vitronectin
chr5_-_64920115 5.76 ENST00000381018.3
ENST00000274327.7
tripartite motif containing 23
chr8_+_126442563 5.67 ENST00000311922.3
tribbles pseudokinase 1
chr12_-_6665200 5.62 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
intermediate filament family orphan 1
chr12_-_772901 5.58 ENST00000305108.4
ninjurin 2
chr8_+_70404996 5.48 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr3_+_9691117 5.40 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
myotubularin related protein 14
chr17_+_65374075 5.39 ENST00000581322.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_+_27435179 5.39 ENST00000606999.1
ENST00000405489.3
all-trans retinoic acid-induced differentiation factor
chr6_+_108977520 5.38 ENST00000540898.1
forkhead box O3
chr6_-_33168391 5.35 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
retinoid X receptor, beta
chr14_+_56585048 5.34 ENST00000267460.4
pellino E3 ubiquitin protein ligase family member 2
chr1_+_192544857 5.33 ENST00000367459.3
ENST00000469578.2
regulator of G-protein signaling 1
chr4_-_186456766 5.33 ENST00000284771.6
PDZ and LIM domain 3
chr14_+_50234827 5.33 ENST00000554589.1
ENST00000557247.1
kelch domain containing 2
chr1_+_207277590 5.32 ENST00000367070.3
complement component 4 binding protein, alpha
chr17_-_26695013 5.30 ENST00000555059.2
Homeobox protein SEBOX
chr2_-_176032843 5.28 ENST00000392544.1
ENST00000409499.1
ENST00000426833.3
ENST00000392543.2
ENST00000538946.1
ENST00000487334.2
ENST00000409833.1
ENST00000409635.1
ENST00000264110.2
ENST00000345739.5
activating transcription factor 2
chr7_-_115608304 5.16 ENST00000457268.1
transcription factor EC
chr14_-_65569186 5.10 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
MYC associated factor X
chr11_-_66336060 5.10 ENST00000310325.5
cathepsin F
chr17_+_65373531 5.04 ENST00000580974.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_-_111781454 5.01 ENST00000533280.1
crystallin, alpha B
chr5_-_150460539 4.97 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNFAIP3 interacting protein 1
chr2_+_27434860 4.93 ENST00000380171.3
all-trans retinoic acid-induced differentiation factor
chr5_+_133451254 4.79 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
transcription factor 7 (T-cell specific, HMG-box)
chr6_+_114178512 4.77 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr5_-_115872142 4.75 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr8_-_134309823 4.74 ENST00000414097.2
N-myc downstream regulated 1
chr9_+_118916082 4.72 ENST00000328252.3
pregnancy-associated plasma protein A, pappalysin 1
chr7_+_5229904 4.69 ENST00000382384.2
WD repeat domain, phosphoinositide interacting 2
chr7_-_115670804 4.68 ENST00000320239.7
transcription factor EC
chr3_-_114866084 4.67 ENST00000357258.3
zinc finger and BTB domain containing 20
chr2_-_88927092 4.65 ENST00000303236.3
eukaryotic translation initiation factor 2-alpha kinase 3
chr15_-_34630234 4.64 ENST00000558667.1
ENST00000561120.1
ENST00000559236.1
ENST00000397702.2
solute carrier family 12 (potassium/chloride transporter), member 6
chr1_-_45956822 4.58 ENST00000372086.3
ENST00000341771.6
testis-specific kinase 2
chr1_+_198126093 4.54 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NIMA-related kinase 7
chr7_-_36764004 4.49 ENST00000431169.1
acyloxyacyl hydrolase (neutrophil)
chr7_-_37024665 4.49 ENST00000396040.2
engulfment and cell motility 1
chr10_+_97515409 4.42 ENST00000371207.3
ENST00000543964.1
ectonucleoside triphosphate diphosphohydrolase 1
chr12_-_123187890 4.42 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr15_-_34629922 4.36 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
solute carrier family 12 (potassium/chloride transporter), member 6
chr16_+_50776021 4.33 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
cylindromatosis (turban tumor syndrome)
chr7_-_36764142 4.33 ENST00000258749.5
ENST00000535891.1
acyloxyacyl hydrolase (neutrophil)
chr14_-_74551172 4.31 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr10_+_99400443 4.27 ENST00000370631.3
phosphatidylinositol 4-kinase type 2 alpha
chr19_-_5978144 4.24 ENST00000340578.6
ENST00000541471.1
ENST00000591736.1
ENST00000587479.1
RAN binding protein 3
chr22_-_39151995 4.22 ENST00000405018.1
ENST00000438058.1
Sad1 and UNC84 domain containing 2
chrX_+_135252050 4.17 ENST00000449474.1
ENST00000345434.3
four and a half LIM domains 1
chr11_-_111781610 4.16 ENST00000525823.1
crystallin, alpha B
chr17_-_65241281 4.15 ENST00000358691.5
ENST00000580168.1
helicase with zinc finger
chr17_+_4618734 4.04 ENST00000571206.1
arrestin, beta 2
chr1_+_179851823 3.99 ENST00000435319.4
torsin A interacting protein 1
chrX_+_135251835 3.94 ENST00000456445.1
four and a half LIM domains 1
chr6_-_152639479 3.94 ENST00000356820.4
spectrin repeat containing, nuclear envelope 1
chr8_-_28243934 3.92 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
zinc finger protein 395
chr11_-_64510409 3.88 ENST00000394429.1
ENST00000394428.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_+_11206925 3.88 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CUGBP, Elav-like family member 2
chr10_-_101380121 3.86 ENST00000370495.4
solute carrier family 25 (mitochondrial iron transporter), member 28
chrX_+_146993534 3.84 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
fragile X mental retardation 1
chr8_-_134309335 3.82 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
N-myc downstream regulated 1
chr17_+_57642886 3.76 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr5_-_146435694 3.76 ENST00000356826.3
protein phosphatase 2, regulatory subunit B, beta
chr20_+_44519948 3.74 ENST00000354880.5
ENST00000191018.5
cathepsin A
chrX_-_54070607 3.71 ENST00000338154.6
ENST00000338946.6
PHD finger protein 8
chr9_-_37465396 3.70 ENST00000307750.4
zinc finger and BTB domain containing 5
chr11_-_111781554 3.69 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr19_-_5978090 3.65 ENST00000592621.1
ENST00000034275.8
ENST00000591092.1
ENST00000591333.1
ENST00000590623.1
ENST00000439268.2
ENST00000587159.1
RAN binding protein 3
chr1_-_202927490 3.57 ENST00000340990.5
adiponectin receptor 1
chr4_-_165305086 3.51 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr14_-_24911971 3.49 ENST00000555365.1
ENST00000399395.3
short chain dehydrogenase/reductase family 39U, member 1
chr5_-_142783175 3.46 ENST00000231509.3
ENST00000394464.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_-_76447494 3.45 ENST00000238682.3
transforming growth factor, beta 3
chr18_+_29171689 3.45 ENST00000237014.3
transthyretin
chr1_+_209878182 3.44 ENST00000367027.3
hydroxysteroid (11-beta) dehydrogenase 1
chr5_-_146435572 3.39 ENST00000394414.1
protein phosphatase 2, regulatory subunit B, beta
chr5_-_150460914 3.38 ENST00000389378.2
TNFAIP3 interacting protein 1
chr6_+_108882069 3.37 ENST00000406360.1
forkhead box O3
chrX_+_37639264 3.36 ENST00000378588.4
cytochrome b-245, beta polypeptide

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
12.0 35.9 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
11.9 131.2 GO:0033227 dsRNA transport(GO:0033227)
5.6 33.8 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
5.6 16.7 GO:0071409 cellular response to cycloheximide(GO:0071409)
5.4 42.9 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
5.3 26.5 GO:0097338 response to clozapine(GO:0097338)
5.1 30.3 GO:0070417 cellular response to cold(GO:0070417)
4.8 24.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
4.5 18.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
4.4 26.5 GO:0051025 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
4.3 56.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
4.3 34.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
3.7 21.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
3.5 28.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
3.5 13.8 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
3.4 13.6 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
3.4 10.1 GO:1990108 protein linear deubiquitination(GO:1990108)
3.2 51.2 GO:0051639 actin filament network formation(GO:0051639)
3.0 20.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
2.9 8.7 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
2.8 8.4 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
2.7 16.2 GO:0090131 mesenchyme migration(GO:0090131)
2.7 10.7 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
2.4 48.7 GO:0002347 response to tumor cell(GO:0002347)
2.3 7.0 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
2.2 21.9 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
2.0 6.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
2.0 30.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
2.0 6.0 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.9 1.9 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
1.9 5.7 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.8 9.1 GO:0051029 rRNA transport(GO:0051029)
1.8 14.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.7 13.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
1.6 12.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.6 25.7 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.6 4.8 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
1.6 6.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
1.6 11.0 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.5 9.2 GO:0006196 AMP catabolic process(GO:0006196)
1.5 6.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.5 20.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.5 5.9 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
1.5 7.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
1.4 4.3 GO:0002276 basophil activation involved in immune response(GO:0002276)
1.4 7.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.3 5.3 GO:0008063 Toll signaling pathway(GO:0008063)
1.3 6.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.3 3.9 GO:0048250 mitochondrial iron ion transport(GO:0048250)
1.2 8.5 GO:0009597 detection of virus(GO:0009597)
1.2 7.0 GO:0051661 maintenance of centrosome location(GO:0051661)
1.2 3.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
1.1 7.9 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.1 11.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
1.1 2.2 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
1.1 5.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.0 4.2 GO:0060613 fat pad development(GO:0060613)
1.0 11.9 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
1.0 21.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
1.0 14.7 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
1.0 4.8 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.9 17.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.9 24.7 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.9 3.5 GO:1905073 ossification involved in bone remodeling(GO:0043932) frontal suture morphogenesis(GO:0060364) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.9 7.7 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.9 15.3 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.9 7.7 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.8 5.9 GO:2000332 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.8 15.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.8 0.8 GO:0007521 muscle cell fate determination(GO:0007521)
0.8 8.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.8 8.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.8 4.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.8 8.6 GO:0090232 peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.8 2.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.7 18.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.7 2.9 GO:1990535 neuron projection maintenance(GO:1990535)
0.7 8.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.7 1.4 GO:0003417 growth plate cartilage development(GO:0003417) cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.7 3.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.7 5.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.7 2.8 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.7 4.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.7 2.8 GO:0021590 cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.7 4.1 GO:0044211 CTP salvage(GO:0044211)
0.7 26.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.7 7.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 10.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.6 5.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.6 1.9 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.6 7.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.6 6.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.6 4.3 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.6 1.7 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.6 5.6 GO:0014831 gastro-intestinal system smooth muscle contraction(GO:0014831)
0.5 3.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.5 6.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.5 2.7 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.5 5.3 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.5 19.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.5 14.8 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.5 0.5 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.5 1.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.5 1.9 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.5 4.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.5 5.1 GO:0071476 cellular hypotonic response(GO:0071476)
0.5 0.9 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.5 17.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.4 1.3 GO:0060920 cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.4 3.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.4 2.2 GO:0021759 globus pallidus development(GO:0021759)
0.4 2.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.4 1.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 18.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.4 4.0 GO:0051764 actin crosslink formation(GO:0051764)
0.4 2.0 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.4 32.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.4 9.0 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.4 1.5 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.4 1.9 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.4 1.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.4 1.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.4 3.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.3 2.8 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3 0.7 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.3 21.8 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.3 1.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.3 3.0 GO:0032329 L-serine transport(GO:0015825) serine transport(GO:0032329)
0.3 5.9 GO:0006479 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.3 1.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 1.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 2.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.3 2.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.3 3.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.3 4.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 1.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.4 GO:1904693 midbrain morphogenesis(GO:1904693)
0.3 4.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.3 8.3 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.3 2.5 GO:0006552 leucine catabolic process(GO:0006552)
0.3 1.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.3 3.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 4.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 5.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.3 4.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 1.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.7 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.2 0.5 GO:0002517 T cell tolerance induction(GO:0002517)
0.2 5.6 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.2 0.9 GO:0010958 regulation of amino acid import(GO:0010958)
0.2 1.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.2 17.4 GO:0045576 mast cell activation(GO:0045576)
0.2 1.7 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2 0.6 GO:0061055 myotome development(GO:0061055)
0.2 0.6 GO:0008355 olfactory learning(GO:0008355)
0.2 5.3 GO:0002076 osteoblast development(GO:0002076)
0.2 3.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 2.5 GO:0008228 opsonization(GO:0008228)
0.2 9.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 0.4 GO:0071883 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2 6.9 GO:0010107 potassium ion import(GO:0010107)
0.2 5.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 2.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 1.5 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.2 0.9 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.2 0.9 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 4.7 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.2 1.1 GO:0060612 adipose tissue development(GO:0060612)
0.2 1.4 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.2 2.8 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.2 0.7 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.2 1.4 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.2 7.4 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.2 1.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 44.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 3.0 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.2 2.0 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 3.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.2 0.2 GO:0060620 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of cholesterol transporter activity(GO:0060694) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.2 9.9 GO:0015914 phospholipid transport(GO:0015914)
0.2 0.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.9 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 22.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.7 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) interferon-beta biosynthetic process(GO:0045350) type I interferon biosynthetic process(GO:0045351) regulation of interferon-alpha biosynthetic process(GO:0045354) regulation of interferon-beta biosynthetic process(GO:0045357)
0.1 0.3 GO:0021764 amygdala development(GO:0021764)
0.1 9.2 GO:0048678 response to axon injury(GO:0048678)
0.1 6.2 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.1 2.4 GO:0001502 cartilage condensation(GO:0001502)
0.1 6.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 2.5 GO:0030155 regulation of cell adhesion(GO:0030155)
0.1 2.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0048867 stem cell fate determination(GO:0048867)
0.1 0.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 6.0 GO:0051646 mitochondrion localization(GO:0051646)
0.1 0.4 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.5 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1 1.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.5 GO:0021997 response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.1 1.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 2.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.4 GO:0042048 olfactory behavior(GO:0042048)
0.1 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 3.5 GO:0090383 phagosome acidification(GO:0090383)
0.1 1.6 GO:0060348 bone development(GO:0060348)
0.1 1.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.5 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 1.3 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 2.6 GO:0016577 histone demethylation(GO:0016577)
0.1 0.4 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 2.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.4 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 6.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.5 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 2.1 GO:0035456 response to interferon-beta(GO:0035456)
0.1 0.7 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.5 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.1 0.6 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.8 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.6 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.5 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.8 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 8.1 GO:0007286 spermatid development(GO:0007286)
0.1 0.5 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.1 6.0 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.9 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.4 GO:0010193 response to ozone(GO:0010193)
0.1 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.8 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.1 GO:0090335 regulation of brown fat cell differentiation(GO:0090335)
0.1 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.9 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.4 GO:0090166 vesicle fusion with Golgi apparatus(GO:0048280) Golgi disassembly(GO:0090166)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.5 GO:0006941 striated muscle contraction(GO:0006941)
0.1 1.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.1 0.3 GO:0006768 biotin metabolic process(GO:0006768)
0.1 1.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.5 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.3 GO:0043316 cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.2 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 2.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.9 GO:0014002 astrocyte development(GO:0014002)
0.0 0.2 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0 0.1 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 1.1 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.6 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.6 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 1.2 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.2 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 1.0 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:1901374 acetate ester transport(GO:1901374)
0.0 1.3 GO:0006968 cellular defense response(GO:0006968)
0.0 1.5 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0086097 positive regulation of phospholipase A2 activity(GO:0032430) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 3.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 1.6 GO:0009267 cellular response to starvation(GO:0009267)
0.0 1.0 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
0.0 0.1 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 5.6 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 21.9 GO:1902636 kinociliary basal body(GO:1902636)
6.1 30.5 GO:0036398 TCR signalosome(GO:0036398)
5.6 45.0 GO:0035976 AP1 complex(GO:0035976)
2.6 18.1 GO:0046581 intercellular canaliculus(GO:0046581)
2.6 51.2 GO:0001891 phagocytic cup(GO:0001891)
2.4 7.2 GO:0044609 DBIRD complex(GO:0044609)
2.3 9.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
2.0 8.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.0 23.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.6 17.1 GO:0033391 chromatoid body(GO:0033391)
1.4 5.8 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.4 30.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
1.4 27.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.2 4.8 GO:0005797 Golgi medial cisterna(GO:0005797)
1.2 38.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
1.1 4.3 GO:0035838 growing cell tip(GO:0035838)
1.0 7.0 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.9 1.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.9 2.7 GO:0019034 viral replication complex(GO:0019034)
0.8 12.9 GO:0097512 cardiac myofibril(GO:0097512)
0.7 18.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.6 8.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6 4.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.6 2.9 GO:0005899 insulin receptor complex(GO:0005899)
0.6 5.8 GO:0097427 microtubule bundle(GO:0097427)
0.6 3.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.6 8.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 1.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.5 19.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.5 1.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.5 4.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.5 7.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.4 7.1 GO:0043073 germ cell nucleus(GO:0043073)
0.4 9.8 GO:0071564 npBAF complex(GO:0071564)
0.4 30.6 GO:0005776 autophagosome(GO:0005776)
0.4 148.4 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.3 1.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 5.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 8.2 GO:0032982 myosin filament(GO:0032982)
0.3 1.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.3 3.5 GO:0005577 fibrinogen complex(GO:0005577)
0.3 9.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 23.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 3.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 9.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 3.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 13.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 5.3 GO:0035861 site of double-strand break(GO:0035861)
0.2 6.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 2.6 GO:0071141 SMAD protein complex(GO:0071141)
0.2 1.9 GO:0016600 flotillin complex(GO:0016600)
0.2 1.9 GO:0071953 elastic fiber(GO:0071953)
0.2 1.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 25.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 5.5 GO:0030018 Z disc(GO:0030018)
0.2 34.2 GO:0030426 growth cone(GO:0030426)
0.2 7.9 GO:0097542 ciliary tip(GO:0097542)
0.2 1.2 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.5 GO:0072686 mitotic spindle(GO:0072686)
0.2 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 7.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 52.6 GO:0000790 nuclear chromatin(GO:0000790)
0.1 1.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 8.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 58.8 GO:0016607 nuclear speck(GO:0016607)
0.1 4.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 8.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 13.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 5.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 9.9 GO:0016605 PML body(GO:0016605)
0.1 19.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 11.2 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.9 GO:0097470 ribbon synapse(GO:0097470)
0.1 4.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 5.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.7 GO:0043203 axon hillock(GO:0043203)
0.1 1.9 GO:0042629 mast cell granule(GO:0042629)
0.1 1.1 GO:0097228 sperm principal piece(GO:0097228)
0.1 8.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 5.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 27.3 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 1.9 GO:0005903 brush border(GO:0005903)
0.1 0.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 4.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 11.6 GO:0005769 early endosome(GO:0005769)
0.0 2.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 10.5 GO:0005886 plasma membrane(GO:0005886)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0005795 Golgi stack(GO:0005795)
0.0 6.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0071817 holo TFIIH complex(GO:0005675) MMXD complex(GO:0071817)
0.0 3.4 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.9 GO:0005770 late endosome(GO:0005770)
0.0 2.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.6 GO:0005874 microtubule(GO:0005874)
0.0 0.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.8 GO:0035579 specific granule membrane(GO:0035579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
21.9 131.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
9.9 29.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
4.5 57.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
4.4 26.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
4.4 21.9 GO:0002046 opsin binding(GO:0002046)
4.4 39.4 GO:0043426 MRF binding(GO:0043426)
2.9 8.8 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
2.8 8.5 GO:0019959 interleukin-8 binding(GO:0019959)
2.7 10.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
2.6 20.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
2.6 12.8 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
2.1 14.6 GO:0008142 oxysterol binding(GO:0008142)
2.0 6.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
2.0 5.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.9 20.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.9 5.6 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.8 30.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
1.7 26.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
1.6 4.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.5 6.1 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
1.4 5.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.4 11.0 GO:0005131 growth hormone receptor binding(GO:0005131)
1.3 4.0 GO:0031859 platelet activating factor receptor binding(GO:0031859)
1.3 13.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
1.2 5.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.2 18.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.2 3.5 GO:0034584 piRNA binding(GO:0034584)
1.2 32.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
1.2 3.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.1 3.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.1 8.0 GO:0042608 T cell receptor binding(GO:0042608)
1.1 4.3 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
1.1 4.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
1.0 11.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.0 10.4 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
1.0 7.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.0 13.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
1.0 9.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.0 5.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.0 26.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
1.0 5.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
1.0 21.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.9 2.8 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.9 7.0 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.8 22.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.8 11.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.8 2.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.8 36.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.7 17.8 GO:0030275 LRR domain binding(GO:0030275)
0.7 2.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.6 1.9 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.6 3.8 GO:0035500 MH2 domain binding(GO:0035500)
0.6 2.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.6 4.1 GO:0004849 uridine kinase activity(GO:0004849)
0.6 6.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.6 16.4 GO:0005521 lamin binding(GO:0005521)
0.6 1.7 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.6 2.8 GO:0004905 type I interferon receptor activity(GO:0004905)
0.6 13.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.6 2.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5 2.7 GO:0034046 poly(G) binding(GO:0034046)
0.5 1.6 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.5 4.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.5 9.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.5 1.5 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.5 1.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.5 0.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.4 8.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 9.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 1.7 GO:0016160 amylase activity(GO:0016160)
0.4 5.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.4 12.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 5.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 8.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.4 1.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.4 2.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.4 1.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 5.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 5.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4 1.4 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.4 6.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.4 5.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.4 1.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.3 20.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 13.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.3 4.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.3 6.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 2.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 10.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.3 5.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 8.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 2.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.3 6.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 5.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 7.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 2.2 GO:0005534 galactose binding(GO:0005534)
0.3 1.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 6.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 18.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.3 2.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 2.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 3.9 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 2.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 9.0 GO:0070412 R-SMAD binding(GO:0070412)
0.2 6.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 3.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 1.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 3.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 31.9 GO:0017124 SH3 domain binding(GO:0017124)
0.2 54.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 49.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 5.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 5.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 40.9 GO:0051015 actin filament binding(GO:0051015)
0.2 0.7 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 0.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 0.7 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 2.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 4.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 10.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 0.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 9.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 3.7 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 6.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 48.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 23.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.4 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.5 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 3.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 7.3 GO:0019003 GDP binding(GO:0019003)
0.1 13.8 GO:0044325 ion channel binding(GO:0044325)
0.1 17.3 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 3.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 2.5 GO:0051087 chaperone binding(GO:0051087)
0.1 13.5 GO:0042393 histone binding(GO:0042393)
0.1 6.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.4 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 3.9 GO:0030145 manganese ion binding(GO:0030145)
0.1 2.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 1.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 6.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 3.1 GO:0008233 peptidase activity(GO:0008233)
0.1 2.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 4.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 7.3 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 3.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 4.5 GO:0019900 kinase binding(GO:0019900)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0031711 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.0 0.9 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.9 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.4 GO:0032934 sterol binding(GO:0032934)
0.0 0.3 GO:0015149 hexose transmembrane transporter activity(GO:0015149)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 11.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.9 47.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.9 21.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.8 27.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.8 53.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.6 67.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.5 22.0 PID MYC PATHWAY C-MYC pathway
0.5 11.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.5 12.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5 12.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 19.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.4 19.3 PID IL3 PATHWAY IL3-mediated signaling events
0.4 13.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.4 2.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.3 7.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 12.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 36.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 9.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.3 18.1 PID LKB1 PATHWAY LKB1 signaling events
0.3 22.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 16.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 13.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 5.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 3.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 5.2 PID CD40 PATHWAY CD40/CD40L signaling
0.2 25.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 5.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 25.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 3.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 16.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 5.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.2 18.1 PID CMYB PATHWAY C-MYB transcription factor network
0.2 0.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 8.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 2.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 7.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 3.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 3.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 4.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 5.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 0.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 39.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 4.5 PID P53 REGULATION PATHWAY p53 pathway
0.1 4.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 10.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 55.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.4 38.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
1.2 13.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.0 24.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.0 53.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.9 28.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.8 11.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.7 29.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.7 34.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.7 19.4 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.7 12.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.6 16.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.5 21.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 5.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.5 11.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.4 19.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 8.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.4 7.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.4 10.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.4 6.5 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.4 9.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 6.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.4 5.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 6.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.3 8.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 3.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 6.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 8.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 4.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 3.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 2.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 1.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 2.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 2.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 4.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 7.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 10.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 15.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 5.2 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.2 4.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 4.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.2 7.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 7.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 1.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.9 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.1 2.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.4 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 0.8 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 0.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 2.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 4.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 5.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 19.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 6.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 5.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 5.4 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 3.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 10.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.6 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.0 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 2.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0 0.5 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins