Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for FOXJ2
Z-value: 0.97
Motif logo
Transcription factors associated with FOXJ2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXJ2 | hg19_v2_chr12_+_8185288_8185339 | -0.16 | 1.9e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXJ2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 36.6 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.2 | 34.6 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 7.0 | 28.0 | GO:0009224 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 4.2 | 25.0 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 1.9 | 22.4 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 5.2 | 21.0 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 2.5 | 20.1 | GO:1900625 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.0 | 18.2 | GO:0042493 | response to drug(GO:0042493) |
| 1.2 | 17.4 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 1.7 | 16.9 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.6 | 34.6 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.9 | 29.3 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 3.6 | 25.0 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 3.2 | 22.4 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.1 | 21.7 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.1 | 21.0 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.2 | 20.9 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 2.9 | 20.1 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 1.2 | 17.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 2.9 | 17.4 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 43.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 4.0 | 28.0 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.9 | 24.7 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.1 | 22.0 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.7 | 20.1 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 18.0 | GO:0016887 | ATPase activity(GO:0016887) |
| 3.5 | 17.4 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 1.7 | 16.9 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.2 | 16.2 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 14.6 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 28.9 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.2 | 20.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.6 | 20.1 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.2 | 14.4 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.2 | 10.5 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 9.8 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.2 | 9.4 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 9.1 | PID P73PATHWAY | p73 transcription factor network |
| 0.2 | 8.9 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.2 | 7.3 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 36.6 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 0.3 | 34.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.8 | 28.0 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.5 | 24.7 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 1.1 | 20.1 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.6 | 16.9 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 14.5 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.8 | 13.5 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.2 | 12.3 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.6 | 11.0 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |