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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for FOXO4

Z-value: 1.61

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Transcription factors associated with FOXO4

Gene Symbol Gene ID Gene Info
FOXO4
ENSG00000184481.12 forkhead box O4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXO4hg19_v2_chrX_+_70316005_703160470.699.4e-32Click!

Activity profile of FOXO4 motif

Sorted Z-values of FOXO4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_42812143 27.62 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr5_-_42811986 27.49 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr1_-_182360918 23.86 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr1_-_57045228 22.44 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_+_6845384 21.52 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr16_+_6069586 21.38 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_-_60097297 20.58 ENST00000395090.1
RTN1
reticulon 1
chr1_-_182360498 19.92 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr3_-_112127981 19.83 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr19_-_36523709 19.76 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chr2_-_71454185 19.63 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr11_-_62476965 18.43 ENST00000405837.1
ENST00000531524.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr8_-_134309823 18.10 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr11_-_62477041 17.70 ENST00000433053.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_+_6069072 15.93 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_-_134309335 15.53 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr20_+_44035200 15.40 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr10_-_90751038 15.25 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr17_-_17875688 15.13 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr14_-_103987679 14.53 ENST00000553610.1
CKB
creatine kinase, brain
chr6_+_101846664 13.66 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
GRIK2
glutamate receptor, ionotropic, kainate 2
chr19_-_37019136 13.56 ENST00000592282.1
ZNF260
zinc finger protein 260
chr6_-_152489484 13.00 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_-_64920115 12.88 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr3_-_28390581 12.68 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr2_+_233527443 12.64 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr20_+_44035847 12.62 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_-_37193606 12.44 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr17_+_17876127 12.39 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48
leucine rich repeat containing 48
chr19_+_50380682 11.99 ENST00000221543.5
TBC1D17
TBC1 domain family, member 17
chr11_-_114466477 11.94 ENST00000375478.3
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr19_+_50380917 11.61 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr16_-_4852915 11.30 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr10_-_73848086 10.89 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr14_+_70918874 10.19 ENST00000603540.1
ADAM21
ADAM metallopeptidase domain 21
chr1_+_43855560 10.07 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr12_-_12491608 9.89 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr9_+_27109133 9.33 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr11_-_114466471 9.29 ENST00000424261.2
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr3_-_48956818 9.21 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr5_-_115872142 9.19 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr9_+_108006880 9.05 ENST00000374723.1
ENST00000374720.3
ENST00000374724.1
SLC44A1
solute carrier family 44 (choline transporter), member 1
chr10_+_111985713 9.03 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr18_-_21852143 8.96 ENST00000399443.3
OSBPL1A
oxysterol binding protein-like 1A
chr18_-_53303123 8.72 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr11_+_46639071 8.60 ENST00000580238.1
ENST00000581416.1
ENST00000529655.1
ENST00000533325.1
ENST00000581438.1
ENST00000583249.1
ENST00000530500.1
ENST00000526508.1
ENST00000578626.1
ENST00000577256.1
ENST00000524625.1
ENST00000582547.1
ENST00000359513.4
ENST00000528494.1
ATG13
autophagy related 13
chr1_+_150229554 8.55 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr12_-_10251576 8.35 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr3_+_138068051 8.26 ENST00000474559.1
MRAS
muscle RAS oncogene homolog
chr5_+_64920543 8.23 ENST00000399438.3
ENST00000510585.2
TRAPPC13
CTC-534A2.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr7_-_37026108 8.16 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr19_-_40732594 8.15 ENST00000430325.2
ENST00000433940.1
CNTD2
cyclin N-terminal domain containing 2
chr14_-_75518129 8.09 ENST00000556257.1
ENST00000557648.1
ENST00000553263.1
ENST00000355774.2
ENST00000380968.2
ENST00000238662.7
MLH3
mutL homolog 3
chr14_+_94577074 8.08 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr15_+_43985725 8.04 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr19_-_58662139 8.00 ENST00000598312.1
ZNF329
zinc finger protein 329
chr11_+_12115543 7.95 ENST00000537344.1
ENST00000532179.1
ENST00000526065.1
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr12_-_10251603 7.76 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr4_+_88754069 7.73 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr7_-_143059780 7.72 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr11_+_46638805 7.68 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
ATG13
autophagy related 13
chr6_+_123110465 7.67 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr11_+_57365150 7.61 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr15_+_43985084 7.61 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr21_-_32931290 7.52 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr6_-_46889694 7.43 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116
G protein-coupled receptor 116
chr1_+_162039558 7.39 ENST00000530878.1
ENST00000361897.5
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr2_+_157292859 7.31 ENST00000438166.2
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr4_-_186696425 7.24 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr7_-_143059845 7.20 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr15_+_43885252 7.17 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr2_+_175260451 6.78 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3
secernin 3
chr4_+_88754113 6.72 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr19_+_1205740 6.48 ENST00000326873.7
STK11
serine/threonine kinase 11
chr10_-_52645379 6.39 ENST00000395489.2
A1CF
APOBEC1 complementation factor
chr5_+_156712372 6.38 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_+_148447887 6.38 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr11_-_94226964 6.31 ENST00000538923.1
ENST00000540013.1
ENST00000407439.3
ENST00000393241.4
MRE11A
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
chr4_-_186697044 6.30 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr2_+_32502952 6.25 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr13_+_32838801 6.22 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr11_-_55703876 6.16 ENST00000301532.3
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr5_-_131132658 6.13 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr6_+_72596604 6.00 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_107703556 5.98 ENST00000496714.1
FBXL17
F-box and leucine-rich repeat protein 17
chr10_-_61900762 5.96 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr17_-_8263538 5.90 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr19_+_30863271 5.83 ENST00000355537.3
ZNF536
zinc finger protein 536
chr18_+_77160282 5.78 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_+_27109392 5.74 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr4_-_90757364 5.67 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr3_+_169490606 5.66 ENST00000349841.5
MYNN
myoneurin
chr10_-_62332357 5.63 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr8_-_42698433 5.62 ENST00000345117.2
ENST00000254250.3
THAP1
THAP domain containing, apoptosis associated protein 1
chr5_-_133706695 5.60 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr15_+_34310428 5.56 ENST00000557872.1
CHRM5
cholinergic receptor, muscarinic 5
chr13_-_41240717 5.51 ENST00000379561.5
FOXO1
forkhead box O1
chr4_+_124320665 5.49 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr17_+_72427477 5.44 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_+_134758827 5.39 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr11_+_112832090 5.38 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr1_-_150669604 5.31 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr14_+_102276192 5.31 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr9_-_15472730 5.29 ENST00000481862.1
PSIP1
PC4 and SFRS1 interacting protein 1
chr6_+_32121908 5.28 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr22_+_45809560 5.24 ENST00000342894.3
ENST00000538017.1
RIBC2
RIB43A domain with coiled-coils 2
chr10_-_52645416 5.17 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr2_-_101767715 5.14 ENST00000376840.4
ENST00000409318.1
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr6_+_32121789 5.00 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr2_-_166060552 4.89 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr19_+_15160130 4.82 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr2_-_183731882 4.79 ENST00000295113.4
FRZB
frizzled-related protein
chr12_+_96588279 4.77 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr13_+_98086445 4.72 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr1_-_13673511 4.62 ENST00000344998.3
ENST00000334600.6
PRAMEF14
PRAME family member 14
chr7_+_106505696 4.60 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr8_-_87755878 4.60 ENST00000320005.5
CNGB3
cyclic nucleotide gated channel beta 3
chr3_+_138067666 4.50 ENST00000475711.1
ENST00000464896.1
MRAS
muscle RAS oncogene homolog
chr17_+_3379284 4.46 ENST00000263080.2
ASPA
aspartoacylase
chr17_-_40897043 4.32 ENST00000428826.2
ENST00000592492.1
ENST00000585893.1
ENST00000593214.1
ENST00000590078.1
ENST00000586382.1
ENST00000415827.2
ENST00000592743.1
ENST00000586089.1
ENST00000435174.1
EZH1
enhancer of zeste homolog 1 (Drosophila)
chr6_-_117747015 4.29 ENST00000368508.3
ENST00000368507.3
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr4_-_100242549 4.29 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr5_-_10308125 4.19 ENST00000296658.3
CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
chr2_-_100721923 4.18 ENST00000356421.2
AFF3
AF4/FMR2 family, member 3
chr7_+_106505912 4.17 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr12_-_102591604 4.12 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr1_-_203151933 4.11 ENST00000404436.2
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr4_-_90756769 4.11 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr8_+_19171128 4.07 ENST00000265807.3
SH2D4A
SH2 domain containing 4A
chr7_-_95225768 4.07 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr16_+_1730338 3.97 ENST00000566691.1
ENST00000382710.4
HN1L
hematological and neurological expressed 1-like
chr16_-_4323015 3.94 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr3_-_101232019 3.93 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr4_-_153332886 3.91 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr7_+_47834908 3.87 ENST00000418326.2
C7orf69
chromosome 7 open reading frame 69
chr1_+_154193325 3.86 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L
ubiquitin associated protein 2-like
chr5_-_141338627 3.83 ENST00000231484.3
PCDH12
protocadherin 12
chr2_-_166060571 3.82 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr20_-_44993012 3.77 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
SLC35C2
solute carrier family 35 (GDP-fucose transporter), member C2
chr2_+_65283506 3.74 ENST00000377990.2
CEP68
centrosomal protein 68kDa
chr17_-_67138015 3.74 ENST00000284425.2
ENST00000590645.1
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr3_-_185826855 3.71 ENST00000306376.5
ETV5
ets variant 5
chr13_+_28712614 3.69 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_113012592 3.60 ENST00000272570.5
ENST00000409573.2
ZC3H8
zinc finger CCCH-type containing 8
chr16_+_77233294 3.48 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr18_-_53069419 3.45 ENST00000570177.2
TCF4
transcription factor 4
chr18_+_60382672 3.39 ENST00000400316.4
ENST00000262719.5
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr1_+_151739131 3.38 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr12_-_71031185 3.37 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr9_-_95186739 3.37 ENST00000375550.4
OMD
osteomodulin
chr15_-_31283618 3.36 ENST00000563714.1
MTMR10
myotubularin related protein 10
chr1_-_153514241 3.35 ENST00000368718.1
ENST00000359215.1
S100A5
S100 calcium binding protein A5
chr17_+_72426891 3.32 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr9_+_5510558 3.30 ENST00000397747.3
PDCD1LG2
programmed cell death 1 ligand 2
chr14_-_99737822 3.23 ENST00000345514.2
ENST00000443726.2
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr15_-_58571445 3.22 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr7_+_134551583 3.20 ENST00000435928.1
CALD1
caldesmon 1
chr19_-_40791302 3.13 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr13_-_99630233 3.12 ENST00000376460.1
ENST00000442173.1
DOCK9
dedicator of cytokinesis 9
chr7_+_99425633 3.09 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
CYP3A43
cytochrome P450, family 3, subfamily A, polypeptide 43
chr1_+_160765860 3.09 ENST00000368037.5
LY9
lymphocyte antigen 9
chr2_+_65283529 3.05 ENST00000546106.1
ENST00000537589.1
ENST00000260569.4
CEP68
centrosomal protein 68kDa
chr5_+_176853702 3.04 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr11_-_46638720 2.99 ENST00000326737.3
HARBI1
harbinger transposase derived 1
chr15_-_55657428 2.97 ENST00000568543.1
CCPG1
cell cycle progression 1
chr5_-_59481406 2.97 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_135809835 2.93 ENST00000264158.8
ENST00000539493.1
ENST00000442034.1
ENST00000425393.1
RAB3GAP1
RAB3 GTPase activating protein subunit 1 (catalytic)
chr1_+_22778337 2.93 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr2_+_33661382 2.91 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_-_14028488 2.89 ENST00000405358.4
ETV1
ets variant 1
chr1_+_160765884 2.88 ENST00000392203.4
LY9
lymphocyte antigen 9
chr12_-_71031220 2.86 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr17_+_67410832 2.83 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_+_160765947 2.82 ENST00000263285.6
ENST00000368039.2
LY9
lymphocyte antigen 9
chr8_+_120079478 2.81 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr1_-_53608249 2.80 ENST00000371494.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr17_+_2240916 2.79 ENST00000574563.1
SGSM2
small G protein signaling modulator 2
chr16_+_28858004 2.74 ENST00000322610.8
SH2B1
SH2B adaptor protein 1
chr11_-_123612319 2.73 ENST00000526252.1
ENST00000530393.1
ENST00000533463.1
ENST00000336139.4
ENST00000529691.1
ENST00000528306.1
ZNF202
zinc finger protein 202
chr10_+_99400443 2.72 ENST00000370631.3
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr1_-_53608289 2.70 ENST00000371491.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr13_-_36920420 2.70 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr1_-_227505826 2.70 ENST00000334218.5
ENST00000366766.2
ENST00000366764.2
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chrX_-_131623982 2.68 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr1_+_10490127 2.63 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
APITD1
APITD1-CORT
apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr3_-_18466026 2.61 ENST00000417717.2
SATB1
SATB homeobox 1
chr10_+_123923105 2.59 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr14_-_92572894 2.57 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr2_+_157292933 2.52 ENST00000540309.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr4_-_70626430 2.50 ENST00000310613.3
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr8_-_42623924 2.50 ENST00000276410.2
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr3_+_159570722 2.50 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr7_-_38389573 2.50 ENST00000390344.2
TRGV5
T cell receptor gamma variable 5
chr1_+_13521973 2.44 ENST00000327795.5
PRAMEF21
PRAME family member 21
chr1_+_160765919 2.43 ENST00000341032.4
ENST00000368041.2
ENST00000368040.1
LY9
lymphocyte antigen 9
chr1_+_13742808 2.42 ENST00000602960.1
PRAMEF20
PRAME family member 20
chr12_-_10251539 2.41 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr16_-_86542455 2.40 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr1_+_117297007 2.39 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr3_-_150920979 2.38 ENST00000309180.5
ENST00000480322.1
GPR171
G protein-coupled receptor 171

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.9 43.8 GO:0006542 glutamine biosynthetic process(GO:0006542)
4.0 19.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
3.6 14.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
3.3 36.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
2.9 11.6 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.7 8.0 GO:0019417 sulfur oxidation(GO:0019417)
2.5 15.3 GO:0090131 mesenchyme migration(GO:0090131)
2.1 16.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
2.0 9.8 GO:0006127 glycerophosphate shuttle(GO:0006127)
2.0 9.8 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
1.9 11.6 GO:0016554 cytidine to uridine editing(GO:0016554)
1.8 7.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.8 5.5 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.8 8.8 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
1.7 40.7 GO:0034389 lipid particle organization(GO:0034389)
1.6 6.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
1.6 11.1 GO:0042426 choline catabolic process(GO:0042426)
1.6 15.7 GO:0006600 creatine metabolic process(GO:0006600)
1.5 6.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
1.5 4.5 GO:0006533 aspartate catabolic process(GO:0006533)
1.3 13.0 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.3 10.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
1.3 9.0 GO:0048014 Tie signaling pathway(GO:0048014)
1.3 7.5 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
1.2 13.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.1 5.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.1 5.5 GO:1902617 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) response to fluoride(GO:1902617)
0.9 2.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.9 2.7 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.9 3.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.9 4.3 GO:0010966 regulation of phosphate transport(GO:0010966)
0.8 8.1 GO:0007144 female meiosis I(GO:0007144)
0.8 10.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.8 4.8 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.8 6.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.8 2.4 GO:1903487 regulation of lactation(GO:1903487)
0.8 3.9 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.8 6.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.8 7.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.8 9.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.7 3.7 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.7 4.7 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.7 5.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.7 2.6 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.6 3.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.6 2.6 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.6 3.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.6 37.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.6 11.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.6 2.3 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.5 12.0 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.5 3.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.5 16.2 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.5 10.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 4.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.5 15.7 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.5 1.5 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.5 2.4 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.5 1.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.4 4.3 GO:0006069 ethanol oxidation(GO:0006069)
0.4 5.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 1.2 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.4 6.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.4 3.8 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) protein O-linked fucosylation(GO:0036066)
0.4 3.4 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.4 4.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4 4.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.4 21.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.4 1.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.4 2.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.4 3.2 GO:0035799 ureter maturation(GO:0035799)
0.4 26.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.4 6.0 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3 0.7 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.3 1.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.3 2.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.3 1.0 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.3 1.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 1.9 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.3 2.2 GO:0009597 detection of virus(GO:0009597)
0.3 3.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 9.0 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.3 4.3 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.2 16.4 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.2 0.5 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 8.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 9.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 1.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 3.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 12.9 GO:0046850 regulation of bone remodeling(GO:0046850)
0.2 2.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 1.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 1.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 5.6 GO:0097484 dendrite extension(GO:0097484)
0.2 9.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.2 0.6 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 3.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 8.7 GO:0019228 neuronal action potential(GO:0019228)
0.2 2.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 8.1 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.2 1.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 2.6 GO:0060004 reflex(GO:0060004)
0.2 1.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 4.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 8.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 1.7 GO:0032264 IMP salvage(GO:0032264)
0.2 12.4 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.2 4.0 GO:0032607 interferon-alpha production(GO:0032607)
0.2 3.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.2 8.5 GO:0015701 bicarbonate transport(GO:0015701)
0.1 18.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.8 GO:0006068 ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068)
0.1 11.3 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 2.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 1.9 GO:0055022 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1 0.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.8 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 2.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 2.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 3.4 GO:0015695 organic cation transport(GO:0015695)
0.1 3.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 26.6 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 3.8 GO:0008038 neuron recognition(GO:0008038)
0.1 2.5 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 0.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.1 3.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 2.3 GO:0035456 response to interferon-beta(GO:0035456)
0.1 1.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 4.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 4.1 GO:0007631 feeding behavior(GO:0007631)
0.1 5.9 GO:0021987 cerebral cortex development(GO:0021987)
0.1 1.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 4.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 5.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.9 GO:0007632 visual behavior(GO:0007632)
0.0 1.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 12.2 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 1.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 4.3 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 2.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.8 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.3 GO:0060292 long term synaptic depression(GO:0060292)
0.0 3.9 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.8 GO:0007035 vacuolar acidification(GO:0007035)
0.0 1.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 3.0 GO:0070268 cornification(GO:0070268)
0.0 1.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.4 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 4.6 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 1.6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.6 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
3.8 15.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.9 8.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
2.7 16.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
2.3 43.8 GO:0097386 glial cell projection(GO:0097386)
2.2 6.5 GO:0036398 TCR signalosome(GO:0036398)
2.0 8.1 GO:0005712 chiasma(GO:0005712)
1.7 10.1 GO:1990130 Iml1 complex(GO:1990130)
1.6 9.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.5 7.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.2 3.7 GO:0031251 PAN complex(GO:0031251)
1.1 11.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.0 13.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.8 58.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.7 11.6 GO:0043194 axon initial segment(GO:0043194)
0.7 2.7 GO:0035838 growing cell tip(GO:0035838)
0.6 8.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.6 3.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.5 1.5 GO:0034657 GID complex(GO:0034657)
0.5 2.3 GO:0005899 insulin receptor complex(GO:0005899)
0.4 13.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 9.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 7.5 GO:0044295 axonal growth cone(GO:0044295)
0.3 28.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 12.9 GO:0009925 basal plasma membrane(GO:0009925)
0.3 49.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.3 8.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 2.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 27.4 GO:0055037 recycling endosome(GO:0055037)
0.2 1.9 GO:0036157 outer dynein arm(GO:0036157)
0.2 0.7 GO:0031213 RSF complex(GO:0031213)
0.2 2.1 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 1.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 3.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 3.2 GO:0030478 actin cap(GO:0030478)
0.2 9.0 GO:0005770 late endosome(GO:0005770)
0.2 2.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 4.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.4 GO:0016013 syntrophin complex(GO:0016013)
0.2 0.8 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 6.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 6.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 4.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 2.0 GO:0071141 SMAD protein complex(GO:0071141)
0.1 3.5 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 4.8 GO:0045095 keratin filament(GO:0045095)
0.1 4.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 19.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.8 GO:0005581 collagen trimer(GO:0005581)
0.1 1.7 GO:0097342 ripoptosome(GO:0097342)
0.1 15.6 GO:0030018 Z disc(GO:0030018)
0.1 1.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 12.7 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 2.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 30.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 2.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 6.2 GO:0030427 site of polarized growth(GO:0030427)
0.1 17.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 12.2 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.7 GO:0032433 filopodium tip(GO:0032433)
0.1 10.7 GO:0031968 organelle outer membrane(GO:0031968)
0.1 5.6 GO:0016605 PML body(GO:0016605)
0.1 3.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 4.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 21.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 3.1 GO:0005938 cell cortex(GO:0005938)
0.0 5.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 9.2 GO:0005635 nuclear envelope(GO:0005635)
0.0 3.3 GO:0098794 postsynapse(GO:0098794)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0042383 sarcolemma(GO:0042383)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
10.9 43.8 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
4.9 19.8 GO:0097001 ceramide binding(GO:0097001)
3.8 30.2 GO:0004111 creatine kinase activity(GO:0004111)
2.9 14.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.5 9.8 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
2.3 9.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
2.1 6.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
2.1 6.2 GO:0005549 odorant binding(GO:0005549)
2.0 9.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
2.0 13.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.7 5.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.5 6.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.5 5.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.3 10.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.3 8.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.1 5.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.1 33.6 GO:0043015 gamma-tubulin binding(GO:0043015)
1.0 4.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.0 19.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.9 12.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 8.1 GO:0019237 satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
0.8 7.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.8 21.1 GO:0005521 lamin binding(GO:0005521)
0.7 4.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.7 2.7 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.7 5.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.7 4.6 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.6 5.8 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.6 4.5 GO:0004046 aminoacylase activity(GO:0004046)
0.6 12.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.5 8.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 13.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 5.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.5 3.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.5 1.9 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.4 10.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 3.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.4 12.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.4 4.1 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.4 8.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 2.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 7.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 7.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 2.3 GO:0043559 insulin binding(GO:0043559)
0.3 8.0 GO:0071949 FAD binding(GO:0071949)
0.3 4.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 3.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 6.8 GO:0016805 dipeptidase activity(GO:0016805)
0.3 5.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 2.6 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.3 1.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 1.8 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.3 11.6 GO:0030507 spectrin binding(GO:0030507)
0.2 6.5 GO:0030275 LRR domain binding(GO:0030275)
0.2 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 3.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 6.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 15.1 GO:0030276 clathrin binding(GO:0030276)
0.2 1.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.2 4.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 11.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 0.6 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 1.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 3.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 2.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 1.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 3.1 GO:0070330 aromatase activity(GO:0070330)
0.2 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 2.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 13.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 2.8 GO:0005537 mannose binding(GO:0005537)
0.1 3.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 21.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 5.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 2.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 32.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 3.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 3.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 3.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 2.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 6.3 GO:0019003 GDP binding(GO:0019003)
0.1 3.9 GO:0070888 E-box binding(GO:0070888)
0.1 2.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 8.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 7.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.4 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.3 GO:0005497 androgen binding(GO:0005497)
0.1 5.4 GO:0001618 virus receptor activity(GO:0001618)
0.1 17.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 3.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 2.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 3.4 GO:0005507 copper ion binding(GO:0005507)
0.0 6.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 5.4 GO:0005179 hormone activity(GO:0005179)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 10.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 5.9 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 12.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 4.1 GO:0019902 phosphatase binding(GO:0019902)
0.0 2.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 2.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 7.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.7 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 2.4 GO:0004518 nuclease activity(GO:0004518)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.3 8.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.3 1.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 33.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 7.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 14.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 5.9 PID CONE PATHWAY Visual signal transduction: Cones
0.2 11.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 3.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 6.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 16.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 9.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 28.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 2.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 6.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 5.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 5.4 PID FGF PATHWAY FGF signaling pathway
0.1 5.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.9 PID MYC PATHWAY C-MYC pathway
0.1 2.9 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.9 PID BARD1 PATHWAY BARD1 signaling events
0.1 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.2 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 3.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 3.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 2.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 4.9 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 14.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 8.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 2.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 43.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.7 6.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.7 22.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.6 5.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.6 8.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.5 13.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.5 4.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.5 11.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 9.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 7.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 11.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 9.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 18.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 8.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.3 15.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 6.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.2 4.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 5.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 7.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 3.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 4.7 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 3.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 3.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 8.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 2.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 25.0 REACTOME MEIOSIS Genes involved in Meiosis
0.2 8.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 7.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 5.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 10.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 5.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 9.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 10.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 3.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 10.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 3.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters