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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for GATA1_GATA4

Z-value: 0.50

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Transcription factors associated with GATA1_GATA4

Gene Symbol Gene ID Gene Info
ENSG00000102145.9 GATA binding protein 1
ENSG00000136574.13 GATA binding protein 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA1hg19_v2_chrX_+_48644962_486449830.633.6e-25Click!
GATA4hg19_v2_chr8_+_11534462_11534475,
hg19_v2_chr8_+_11561660_11561751
0.503.8e-15Click!

Activity profile of GATA1_GATA4 motif

Sorted Z-values of GATA1_GATA4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_43513187 47.01 ENST00000540029.1
ENST00000441366.2
erythrocyte membrane protein band 4.2
chr12_-_54689532 38.47 ENST00000540264.2
ENST00000312156.4
nuclear factor, erythroid 2
chr1_+_25598989 36.13 ENST00000454452.2
Rh blood group, D antigen
chr19_-_13213662 33.05 ENST00000264824.4
lymphoblastic leukemia derived sequence 1
chr10_-_99531709 28.36 ENST00000266066.3
secreted frizzled-related protein 5
chr16_+_202686 27.39 ENST00000252951.2
hemoglobin, zeta
chr19_-_12997995 24.79 ENST00000264834.4
Kruppel-like factor 1 (erythroid)
chr11_-_5255861 24.70 ENST00000380299.3
hemoglobin, delta
chr10_+_118305435 23.47 ENST00000369221.2
pancreatic lipase
chr16_+_31539183 22.23 ENST00000302312.4
alpha hemoglobin stabilizing protein
chr11_-_5271122 21.56 ENST00000330597.3
hemoglobin, gamma A
chr6_+_41010293 20.63 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
translocator protein 2
chr1_+_25599018 20.45 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
Rh blood group, D antigen
chr6_-_35765088 20.13 ENST00000259938.2
colipase, pancreatic
chr1_-_25747283 19.55 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
Rh blood group, CcEe antigens
chr11_-_5255696 19.51 ENST00000292901.3
ENST00000417377.1
hemoglobin, delta
chr7_-_100239132 18.70 ENST00000223051.3
ENST00000431692.1
transferrin receptor 2
chr8_-_86290333 18.33 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr1_+_25598872 18.21 ENST00000328664.4
Rh blood group, D antigen
chr11_+_118958689 18.01 ENST00000535253.1
ENST00000392841.1
hydroxymethylbilane synthase
chr19_-_11494975 17.82 ENST00000222139.6
ENST00000592375.2
erythropoietin receptor
chr6_-_52628271 17.33 ENST00000493422.1
glutathione S-transferase alpha 2
chrX_-_55057403 16.76 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
aminolevulinate, delta-, synthase 2
chr4_-_144940477 15.84 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
glycophorin B (MNS blood group)
chr19_-_55669093 15.26 ENST00000344887.5
troponin I type 3 (cardiac)
chr11_-_116708302 15.15 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
apolipoprotein A-I
chr1_+_22303503 14.99 ENST00000337107.6
chymotrypsin-like elastase family, member 3B
chr12_-_114841703 14.99 ENST00000526441.1
T-box 5
chr1_+_22328144 14.95 ENST00000290122.3
ENST00000374663.1
chymotrypsin-like elastase family, member 3A
chr14_+_24584508 14.92 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DDB1 and CUL4 associated factor 11
chr7_+_130020180 14.90 ENST00000481342.1
ENST00000011292.3
ENST00000604896.1
carboxypeptidase A1 (pancreatic)
chr19_+_10397621 14.09 ENST00000380770.3
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr17_-_47841485 14.08 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr1_-_158656488 13.69 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_-_150652924 13.65 ENST00000330883.4
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_+_128563652 13.16 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr14_-_21945057 13.04 ENST00000397762.1
RAB2B, member RAS oncogene family
chr19_+_10397648 12.97 ENST00000340992.4
ENST00000393717.2
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr7_+_80275621 12.42 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr7_-_99332719 12.31 ENST00000336374.2
cytochrome P450, family 3, subfamily A, polypeptide 7
chr1_-_153113927 11.70 ENST00000368752.4
small proline-rich protein 2B
chr1_+_206317450 11.64 ENST00000358184.2
ENST00000361052.3
ENST00000360218.2
cathepsin E
chr16_+_58283814 11.52 ENST00000443128.2
ENST00000219299.4
coiled-coil domain containing 113
chr1_+_43291220 10.65 ENST00000372514.3
erythroblast membrane-associated protein (Scianna blood group)
chr6_-_30128657 10.47 ENST00000449742.2
ENST00000376704.3
tripartite motif containing 10
chr1_+_161136180 10.09 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
protoporphyrinogen oxidase
chr4_+_154387480 10.05 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
chr12_-_120765565 9.81 ENST00000423423.3
ENST00000308366.4
phospholipase A2, group IB (pancreas)
chr4_-_72649763 9.75 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr1_+_205225319 9.68 ENST00000329800.7
transmembrane and coiled-coil domain family 2
chr14_-_24584138 9.48 ENST00000558280.1
ENST00000561028.1
neural retina leucine zipper
chr8_-_41655107 9.29 ENST00000347528.4
ENST00000289734.7
ENST00000379758.2
ENST00000396945.1
ENST00000396942.1
ENST00000352337.4
ankyrin 1, erythrocytic
chr4_+_74275057 9.27 ENST00000511370.1
albumin
chr9_+_33795533 9.18 ENST00000379405.3
protease, serine, 3
chr7_+_80275752 9.12 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr7_-_99381884 8.86 ENST00000336411.2
cytochrome P450, family 3, subfamily A, polypeptide 4
chr6_-_33168391 8.77 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
retinoid X receptor, beta
chr4_-_145061788 8.76 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
glycophorin A (MNS blood group)
glycophorin B (MNS blood group)
chr3_-_119379427 8.69 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
popeye domain containing 2
chr4_+_74269956 8.67 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr18_+_19749386 8.51 ENST00000269216.3
GATA binding protein 6
chr1_+_15783222 8.28 ENST00000359621.4
chymotrypsin-like elastase family, member 2A
chrX_-_65253506 8.05 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr6_-_46889694 7.87 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
G protein-coupled receptor 116
chr16_-_75241050 7.84 ENST00000303037.8
chymotrypsinogen B2
chr11_-_113746212 7.82 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
ubiquitin specific peptidase 28
chr6_-_46048116 7.80 ENST00000185206.6
chloride intracellular channel 5
chr12_-_91573132 7.76 ENST00000550563.1
ENST00000546370.1
decorin
chr2_+_3642545 7.75 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
collectin sub-family member 11
chr4_-_74847800 7.60 ENST00000296029.3
platelet factor 4
chr4_-_144826682 7.58 ENST00000358615.4
ENST00000437468.2
glycophorin E (MNS blood group)
chr11_-_57158109 7.57 ENST00000525955.1
ENST00000533605.1
ENST00000311862.5
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr7_+_142457315 7.47 ENST00000486171.1
ENST00000311737.7
protease, serine, 1 (trypsin 1)
chr2_+_234959376 7.42 ENST00000425558.1
secreted phosphoprotein 2, 24kDa
chr12_-_6233828 7.39 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chrX_+_38211777 7.19 ENST00000039007.4
ornithine carbamoyltransferase
chr14_+_95047744 7.16 ENST00000553511.1
ENST00000554633.1
ENST00000555681.1
ENST00000554276.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr3_-_58196688 7.11 ENST00000486455.1
deoxyribonuclease I-like 3
chr1_-_27240455 6.91 ENST00000254227.3
nuclear receptor subfamily 0, group B, member 2
chr12_-_15103621 6.88 ENST00000536592.1
Rho GDP dissociation inhibitor (GDI) beta
chr17_-_29641084 6.85 ENST00000544462.1
ecotropic viral integration site 2B
chr14_+_102276192 6.83 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr4_-_103266355 6.69 ENST00000424970.2
solute carrier family 39 (zinc transporter), member 8
chr17_+_37824217 6.66 ENST00000394246.1
phenylethanolamine N-methyltransferase
chr1_-_201368707 6.64 ENST00000391967.2
ladinin 1
chr9_+_33240157 6.57 ENST00000379721.3
serine peptidase inhibitor, Kazal type 4
chr17_+_41857793 6.53 ENST00000449302.3
chromosome 17 open reading frame 105
chrX_+_128913906 6.50 ENST00000356892.3
SAM and SH3 domain containing 3
chr10_+_70847852 6.45 ENST00000242465.3
serglycin
chr16_+_333152 6.40 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
protein disulfide isomerase family A, member 2
chr8_-_20040601 6.39 ENST00000265808.7
ENST00000522513.1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr16_+_71560154 6.36 ENST00000539698.3
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr1_-_201368653 6.32 ENST00000367313.3
ladinin 1
chr16_+_71560023 6.28 ENST00000572450.1
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr1_-_24469602 6.17 ENST00000270800.1
interleukin 22 receptor, alpha 1
chr10_+_96443204 6.00 ENST00000339022.5
cytochrome P450, family 2, subfamily C, polypeptide 18
chr1_-_54872059 5.99 ENST00000371320.3
single stranded DNA binding protein 3
chr10_+_118350522 5.97 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
pancreatic lipase-related protein 1
chr2_+_79347577 5.88 ENST00000233735.1
regenerating islet-derived 1 alpha
chr17_-_64225508 5.83 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr3_-_98312548 5.79 ENST00000264193.2
coproporphyrinogen oxidase
chr1_-_175162048 5.79 ENST00000444639.1
KIAA0040
chr5_-_135290705 5.78 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr2_+_220379052 5.75 ENST00000347842.3
ENST00000358078.4
acid-sensing (proton-gated) ion channel family member 4
chr1_+_199996702 5.74 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr12_-_14996355 5.70 ENST00000228936.4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr11_-_1036706 5.62 ENST00000421673.2
mucin 6, oligomeric mucus/gel-forming
chr17_+_4675175 5.62 ENST00000270560.3
transmembrane 4 L six family member 5
chr5_-_141061777 5.61 ENST00000239440.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr17_+_4835580 5.56 ENST00000329125.5
glycoprotein Ib (platelet), alpha polypeptide
chr8_-_20040638 5.55 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr5_-_141061759 5.45 ENST00000508305.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr12_+_9102632 5.43 ENST00000539240.1
killer cell lectin-like receptor subfamily G, member 1
chr10_+_118350468 5.35 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
pancreatic lipase-related protein 1
chr7_-_99277610 5.33 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
cytochrome P450, family 3, subfamily A, polypeptide 5
chr12_-_10151773 5.28 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr19_+_1041212 5.26 ENST00000433129.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr16_+_67840668 5.25 ENST00000415766.3
translin-associated factor X interacting protein 1
chr12_-_91573249 5.15 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr14_-_23877474 5.12 ENST00000405093.3
myosin, heavy chain 6, cardiac muscle, alpha
chr2_-_88427568 5.10 ENST00000393750.3
ENST00000295834.3
fatty acid binding protein 1, liver
chr10_+_74451883 5.08 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr2_+_234959323 5.04 ENST00000373368.1
ENST00000168148.3
secreted phosphoprotein 2, 24kDa
chr11_+_10477733 4.96 ENST00000528723.1
adenosine monophosphate deaminase 3
chr1_+_198608146 4.96 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr19_-_51522955 4.94 ENST00000358789.3
kallikrein-related peptidase 10
chr12_+_32655048 4.87 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr19_+_36132631 4.84 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ets variant 2
chr12_-_9268707 4.83 ENST00000318602.7
alpha-2-macroglobulin
chr6_-_32498046 4.80 ENST00000374975.3
major histocompatibility complex, class II, DR beta 5
chr2_-_89459813 4.71 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr4_-_186697044 4.70 ENST00000437304.2
sorbin and SH3 domain containing 2
chr10_-_104597286 4.68 ENST00000369887.3
cytochrome P450, family 17, subfamily A, polypeptide 1
chr5_+_59783941 4.66 ENST00000506884.1
ENST00000504876.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr2_+_189156638 4.63 ENST00000410051.1
GULP, engulfment adaptor PTB domain containing 1
chr1_+_22351977 4.62 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
long intergenic non-protein coding RNA 339
chr19_-_51568324 4.60 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
kallikrein-related peptidase 13
chr2_+_103035102 4.58 ENST00000264260.2
interleukin 18 receptor accessory protein
chr15_-_58306295 4.57 ENST00000559517.1
aldehyde dehydrogenase 1 family, member A2
chr1_-_155270770 4.55 ENST00000392414.3
pyruvate kinase, liver and RBC
chr12_-_96390063 4.55 ENST00000541929.1
histidine ammonia-lyase
chr5_+_140480083 4.53 ENST00000231130.2
protocadherin beta 3
chr12_+_94071341 4.49 ENST00000542893.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr9_-_124132483 4.48 ENST00000286713.2
ENST00000538954.1
ENST00000347359.2
stomatin
chr22_-_29784519 4.43 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
adaptor-related protein complex 1, beta 1 subunit
chr6_+_7108210 4.39 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr11_-_64684672 4.29 ENST00000377264.3
ENST00000421419.2
autophagy related 2A
chr3_-_187009646 4.27 ENST00000296280.6
ENST00000392470.2
ENST00000169293.6
ENST00000439271.1
ENST00000392472.2
ENST00000392475.2
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr19_-_51487071 4.26 ENST00000391807.1
ENST00000593904.1
kallikrein-related peptidase 7
chr6_-_150039249 4.25 ENST00000543571.1
large tumor suppressor kinase 1
chr6_-_87804815 4.23 ENST00000369582.2
glycoprotein hormones, alpha polypeptide
chr11_-_125550764 4.19 ENST00000527795.1
acrosomal vesicle protein 1
chr2_-_228028829 4.16 ENST00000396625.3
ENST00000329662.7
collagen, type IV, alpha 4
chr11_-_85393886 4.15 ENST00000534224.1
CREB/ATF bZIP transcription factor
chr1_-_120311517 4.14 ENST00000369406.3
ENST00000544913.2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr1_-_153029980 4.14 ENST00000392653.2
small proline-rich protein 2A
chr14_+_22977587 4.13 ENST00000390504.1
T cell receptor alpha joining 33
chr9_-_97356075 4.10 ENST00000375337.3
fructose-1,6-bisphosphatase 2
chr15_-_34610962 4.10 ENST00000290209.5
solute carrier family 12 (potassium/chloride transporter), member 6
chr8_-_72274467 4.09 ENST00000340726.3
eyes absent homolog 1 (Drosophila)
chr19_-_51327034 4.09 ENST00000301420.2
ENST00000448701.2
kallikrein 1
chr11_+_128563948 4.08 ENST00000534087.2
Fli-1 proto-oncogene, ETS transcription factor
chr3_+_48264816 4.08 ENST00000296435.2
ENST00000576243.1
cathelicidin antimicrobial peptide
chr14_-_65409438 4.06 ENST00000557049.1
glutathione peroxidase 2 (gastrointestinal)
chr14_+_60975644 4.06 ENST00000327720.5
SIX homeobox 6
chr6_-_52710893 4.05 ENST00000284562.2
glutathione S-transferase alpha 5
chr1_-_153013588 3.94 ENST00000360379.3
small proline-rich protein 2D
chr3_-_58196939 3.94 ENST00000394549.2
ENST00000461914.3
deoxyribonuclease I-like 3
chr19_-_4066890 3.93 ENST00000322357.4
zinc finger and BTB domain containing 7A
chr2_-_89619904 3.93 ENST00000498574.1
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr8_+_21823726 3.91 ENST00000433566.4
exportin 7
chr7_+_100318423 3.88 ENST00000252723.2
erythropoietin
chr12_-_8218997 3.87 ENST00000307637.4
complement component 3a receptor 1
chr10_-_52645416 3.87 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
APOBEC1 complementation factor
chr2_+_170366203 3.85 ENST00000284669.1
kelch-like family member 41
chr6_-_27840099 3.84 ENST00000328488.2
histone cluster 1, H3i
chr8_+_121137333 3.80 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
collagen, type XIV, alpha 1
chr4_+_78432907 3.78 ENST00000286758.4
chemokine (C-X-C motif) ligand 13
chr17_+_37824411 3.76 ENST00000269582.2
phenylethanolamine N-methyltransferase
chr14_-_21566731 3.76 ENST00000360947.3
zinc finger protein 219
chr19_+_35739897 3.72 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
lipolysis stimulated lipoprotein receptor
chr12_+_53818855 3.69 ENST00000550839.1
anti-Mullerian hormone receptor, type II
chr14_-_90798418 3.67 ENST00000354366.3
NRDE-2, necessary for RNA interference, domain containing
chr5_+_121647764 3.66 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
synuclein, alpha interacting protein
chr2_-_100721923 3.66 ENST00000356421.2
AF4/FMR2 family, member 3
chr11_-_47374246 3.62 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
myosin binding protein C, cardiac
chr11_-_64510409 3.61 ENST00000394429.1
ENST00000394428.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr7_+_39125365 3.61 ENST00000559001.1
ENST00000464276.2
POU class 6 homeobox 2
chr8_-_93107827 3.61 ENST00000520724.1
ENST00000518844.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_+_41136216 3.59 ENST00000562057.1
ENST00000344051.4
serine peptidase inhibitor, Kunitz type 1
chr6_+_7107830 3.58 ENST00000379933.3
ras responsive element binding protein 1
chr21_-_37852359 3.58 ENST00000399137.1
ENST00000399135.1
claudin 14
chr15_-_64126084 3.56 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr10_+_114710425 3.55 ENST00000352065.5
ENST00000369395.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr17_-_42466864 3.55 ENST00000353281.4
ENST00000262407.5
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr1_+_171217622 3.53 ENST00000433267.1
ENST00000367750.3
flavin containing monooxygenase 1
chr15_-_34628951 3.50 ENST00000397707.2
ENST00000560611.1
solute carrier family 12 (potassium/chloride transporter), member 6
chr6_+_31582961 3.50 ENST00000376059.3
ENST00000337917.7
allograft inflammatory factor 1
chr4_-_103266219 3.50 ENST00000394833.2
solute carrier family 39 (zinc transporter), member 8
chr4_-_68749745 3.50 ENST00000283916.6
transmembrane protease, serine 11D

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA1_GATA4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.7 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
7.1 28.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
6.8 74.4 GO:0043249 erythrocyte maturation(GO:0043249)
6.0 17.9 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
5.0 15.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
4.7 65.8 GO:0015671 oxygen transport(GO:0015671)
4.5 13.6 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
4.5 18.2 GO:0009822 alkaloid catabolic process(GO:0009822)
3.8 15.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
3.7 48.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
3.4 77.8 GO:0044241 lipid digestion(GO:0044241)
3.1 18.7 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
3.1 99.1 GO:0015695 organic cation transport(GO:0015695)
3.1 12.3 GO:0002933 lipid hydroxylation(GO:0002933)
2.9 29.1 GO:0001955 blood vessel maturation(GO:0001955)
2.8 8.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
2.6 10.4 GO:0042418 epinephrine biosynthetic process(GO:0042418)
2.6 10.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
2.4 7.2 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
2.4 11.9 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
2.4 7.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
2.4 9.5 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
2.2 6.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
2.1 8.3 GO:0002215 defense response to nematode(GO:0002215)
1.9 15.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
1.9 5.6 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
1.8 8.9 GO:0061113 pancreas morphogenesis(GO:0061113)
1.8 7.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
1.8 5.3 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
1.7 6.9 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.7 6.9 GO:0071461 cellular response to redox state(GO:0071461)
1.6 11.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
1.5 7.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.5 4.4 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.5 4.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
1.5 2.9 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
1.4 7.2 GO:0061107 seminal vesicle development(GO:0061107)
1.4 7.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.4 24.2 GO:0020027 hemoglobin metabolic process(GO:0020027)
1.4 12.6 GO:0006477 protein sulfation(GO:0006477)
1.4 17.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.3 16.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.3 5.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.3 7.9 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.3 3.8 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
1.2 3.6 GO:0048867 stem cell fate determination(GO:0048867)
1.2 30.0 GO:0006337 nucleosome disassembly(GO:0006337)
1.1 6.6 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.1 6.4 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
1.1 5.3 GO:0032971 regulation of muscle filament sliding(GO:0032971)
1.1 1.1 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
1.0 22.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.0 4.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
1.0 10.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.0 3.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
1.0 5.0 GO:0048539 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
1.0 2.9 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
1.0 4.8 GO:0006041 glucosamine metabolic process(GO:0006041)
1.0 4.8 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.9 24.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.9 3.7 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.9 4.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.9 2.7 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.9 2.7 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.9 2.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.9 3.5 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.9 2.6 GO:0001694 histamine biosynthetic process(GO:0001694)
0.9 17.2 GO:0035855 megakaryocyte development(GO:0035855)
0.9 3.4 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.9 6.0 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.8 4.2 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.8 5.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.8 2.5 GO:0061386 closure of optic fissure(GO:0061386)
0.8 7.6 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.8 2.5 GO:0003285 septum secundum development(GO:0003285)
0.8 5.0 GO:0006196 AMP catabolic process(GO:0006196)
0.8 4.8 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.8 7.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.8 2.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.8 3.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.8 2.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.7 3.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.7 3.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.7 2.2 GO:1903487 regulation of lactation(GO:1903487)
0.7 3.5 GO:0015811 L-cystine transport(GO:0015811)
0.7 2.7 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.7 2.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.6 3.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.6 4.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.6 3.2 GO:0072248 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.6 5.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.6 2.5 GO:0007538 primary sex determination(GO:0007538)
0.6 3.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.6 11.6 GO:0016540 protein autoprocessing(GO:0016540)
0.6 4.9 GO:0070995 NADPH oxidation(GO:0070995)
0.6 2.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.6 5.4 GO:0035799 ureter maturation(GO:0035799)
0.6 1.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.6 1.8 GO:0050917 sensory perception of umami taste(GO:0050917)
0.6 2.4 GO:0072166 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.6 2.9 GO:0006526 arginine biosynthetic process(GO:0006526)
0.6 6.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 11.0 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.6 2.3 GO:0007525 somatic muscle development(GO:0007525)
0.6 2.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.6 2.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.5 13.7 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.5 1.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.5 1.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.5 9.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.5 17.3 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.5 5.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.5 4.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.5 3.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.5 15.2 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.5 2.4 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.5 0.9 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.5 22.6 GO:0018149 peptide cross-linking(GO:0018149)
0.5 2.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 1.8 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.5 1.4 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.4 1.3 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 2.2 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.4 1.3 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 9.7 GO:0042359 vitamin D metabolic process(GO:0042359)
0.4 1.8 GO:0036269 swimming behavior(GO:0036269)
0.4 1.3 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.4 6.5 GO:0006702 androgen biosynthetic process(GO:0006702)
0.4 21.4 GO:0015701 bicarbonate transport(GO:0015701)
0.4 1.6 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.4 1.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 1.2 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.4 4.1 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.4 5.7 GO:0006525 arginine metabolic process(GO:0006525)
0.4 6.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.4 10.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.4 8.0 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.4 26.8 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.4 2.0 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.4 5.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 5.5 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.4 3.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.4 3.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.4 3.1 GO:0034378 chylomicron assembly(GO:0034378)
0.4 3.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.4 3.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 1.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.0 GO:0003266 regulation of secondary heart field cardioblast proliferation(GO:0003266)
0.3 1.0 GO:0045113 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.3 4.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.3 3.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.3 2.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 2.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 3.3 GO:0006069 ethanol oxidation(GO:0006069)
0.3 5.3 GO:0030220 platelet formation(GO:0030220)
0.3 2.0 GO:2000807 regulation of presynaptic membrane organization(GO:1901629) regulation of synaptic vesicle clustering(GO:2000807)
0.3 2.3 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 1.3 GO:0002884 type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.3 1.9 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.3 3.9 GO:0006657 CDP-choline pathway(GO:0006657)
0.3 1.6 GO:0015886 heme transport(GO:0015886)
0.3 1.6 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 0.6 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.3 1.6 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 0.9 GO:0008050 female courtship behavior(GO:0008050)
0.3 2.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.3 2.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.3 5.9 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 4.6 GO:0006825 copper ion transport(GO:0006825)
0.3 2.3 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.3 3.6 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.3 2.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.3 1.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.3 3.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 2.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 2.8 GO:0015074 DNA integration(GO:0015074)
0.3 5.3 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.2 2.5 GO:0051607 defense response to virus(GO:0051607)
0.2 1.0 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.6 GO:0045007 depurination(GO:0045007)
0.2 0.7 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.2 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 2.7 GO:0045059 positive thymic T cell selection(GO:0045059)
0.2 2.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 2.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 1.5 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.2 3.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 1.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.2 1.0 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 1.6 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 3.6 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 1.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 3.4 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 2.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 4.3 GO:0044804 nucleophagy(GO:0044804)
0.2 0.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 2.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.2 2.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 3.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 3.6 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.2 1.4 GO:0042060 wound healing(GO:0042060)
0.2 1.6 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.2 2.9 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.2 1.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 8.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 1.7 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2 2.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.5 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 4.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 4.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 3.7 GO:0016246 RNA interference(GO:0016246)
0.2 1.4 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 0.3 GO:0051597 response to methylmercury(GO:0051597)
0.2 11.2 GO:0006968 cellular defense response(GO:0006968)
0.2 1.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 3.4 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 2.4 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 13.3 GO:0046849 bone remodeling(GO:0046849)
0.1 1.2 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.1 1.0 GO:0030856 regulation of epithelial cell differentiation(GO:0030856)
0.1 0.7 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 5.1 GO:0010107 potassium ion import(GO:0010107)
0.1 3.6 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 3.8 GO:0070207 protein homotrimerization(GO:0070207)
0.1 7.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 12.2 GO:0046718 viral entry into host cell(GO:0046718)
0.1 5.5 GO:0007099 centriole replication(GO:0007099)
0.1 1.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 4.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.9 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.8 GO:0002924 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890) negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 1.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 1.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 6.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 1.4 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.1 1.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 6.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 1.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124) regulation of GTP binding(GO:1904424)
0.1 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.1 GO:0006833 water transport(GO:0006833)
0.1 0.4 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 14.7 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 4.8 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.1 1.1 GO:0060438 trachea development(GO:0060438)
0.1 0.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 1.6 GO:0034332 adherens junction organization(GO:0034332)
0.1 2.0 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 2.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 3.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.1 4.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 3.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 2.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.9 GO:0048665 neuron fate specification(GO:0048665)
0.1 2.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 1.0 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.1 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.1 4.3 GO:0016266 O-glycan processing(GO:0016266)
0.1 2.3 GO:0030239 myofibril assembly(GO:0030239)
0.1 15.7 GO:0016567 protein ubiquitination(GO:0016567)
0.1 0.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 2.2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.1 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 2.1 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.6 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 6.1 GO:1990748 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.3 GO:0030155 regulation of cell adhesion(GO:0030155)
0.1 3.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 7.6 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.1 1.4 GO:0001501 skeletal system development(GO:0001501)
0.1 3.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 4.6 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.7 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 3.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 4.3 GO:0034644 cellular response to UV(GO:0034644)
0.1 1.1 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 1.9 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 3.4 GO:0002027 regulation of heart rate(GO:0002027)
0.1 2.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.9 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 1.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 1.9 GO:0019228 neuronal action potential(GO:0019228)
0.1 1.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 4.2 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.1 1.6 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.6 GO:0051028 mRNA transport(GO:0051028)
0.0 1.9 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.6 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 2.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 3.5 GO:0070268 cornification(GO:0070268)
0.0 3.9 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.6 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 2.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 6.7 GO:0007601 visual perception(GO:0007601)
0.0 4.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.6 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 2.4 GO:0031214 biomineral tissue development(GO:0031214)
0.0 0.5 GO:0010039 response to iron ion(GO:0010039)
0.0 0.7 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 1.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 2.9 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 3.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.8 GO:0030324 lung development(GO:0030324)
0.0 1.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0031424 keratinization(GO:0031424)
0.0 0.7 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.9 GO:0006954 inflammatory response(GO:0006954)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.9 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.0 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 1.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.5 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557)
0.0 1.1 GO:0007498 mesoderm development(GO:0007498)
0.0 3.3 GO:0050900 leukocyte migration(GO:0050900)
0.0 0.9 GO:2000278 regulation of DNA biosynthetic process(GO:2000278)
0.0 3.1 GO:0030198 extracellular matrix organization(GO:0030198)
0.0 0.4 GO:0006953 acute-phase response(GO:0006953)
0.0 0.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.7 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.9 GO:0016042 lipid catabolic process(GO:0016042)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 106.3 GO:0005833 hemoglobin complex(GO:0005833)
5.0 15.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
2.8 16.9 GO:1990584 cardiac Troponin complex(GO:1990584)
2.7 13.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
2.5 7.6 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
2.4 7.2 GO:0097183 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
2.0 13.7 GO:0032437 cuticular plate(GO:0032437)
1.8 7.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.4 18.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
1.3 5.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.3 3.9 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.3 5.1 GO:1990246 uniplex complex(GO:1990246)
1.2 7.1 GO:0061689 tricellular tight junction(GO:0061689)
1.1 16.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.1 7.6 GO:0097209 epidermal lamellar body(GO:0097209)
1.1 6.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
1.0 17.4 GO:0031089 platelet dense granule lumen(GO:0031089)
1.0 4.0 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.8 7.5 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.7 22.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.7 12.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.7 2.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.6 5.1 GO:0045179 apical cortex(GO:0045179)
0.6 9.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.6 2.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.5 6.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.5 4.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.5 3.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.5 5.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.5 2.9 GO:0030061 mitochondrial crista(GO:0030061)
0.5 3.8 GO:0005593 FACIT collagen trimer(GO:0005593)
0.5 2.4 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.5 14.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.4 2.7 GO:1990037 Lewy body core(GO:1990037)
0.4 12.3 GO:0034451 centriolar satellite(GO:0034451)
0.4 3.4 GO:0042382 paraspeckles(GO:0042382)
0.4 3.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 2.0 GO:0005899 insulin receptor complex(GO:0005899)
0.4 3.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 10.1 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.4 4.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 6.1 GO:0042588 zymogen granule(GO:0042588)
0.3 41.3 GO:0030863 cortical cytoskeleton(GO:0030863)
0.3 5.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 2.5 GO:0030897 HOPS complex(GO:0030897)
0.3 60.0 GO:0032993 protein-DNA complex(GO:0032993)
0.3 5.8 GO:0032982 myosin filament(GO:0032982)
0.3 2.3 GO:0071439 clathrin complex(GO:0071439)
0.3 1.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 8.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 4.9 GO:0042101 T cell receptor complex(GO:0042101)
0.2 3.9 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 49.3 GO:0072562 blood microparticle(GO:0072562)
0.2 1.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 11.9 GO:0001533 cornified envelope(GO:0001533)
0.2 0.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 4.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.8 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 2.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 1.3 GO:0002177 manchette(GO:0002177)
0.2 1.1 GO:1990393 3M complex(GO:1990393)
0.2 9.5 GO:0034707 chloride channel complex(GO:0034707)
0.2 8.7 GO:0042734 presynaptic membrane(GO:0042734)
0.2 4.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 3.9 GO:0031143 pseudopodium(GO:0031143)
0.2 9.9 GO:0005604 basement membrane(GO:0005604)
0.2 1.1 GO:0097440 apical dendrite(GO:0097440)
0.2 1.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 1.6 GO:0030057 desmosome(GO:0030057)
0.2 8.5 GO:0005796 Golgi lumen(GO:0005796)
0.2 1.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 7.3 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.2 2.2 GO:0043083 synaptic cleft(GO:0043083)
0.2 2.6 GO:0033270 paranode region of axon(GO:0033270)
0.1 7.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 5.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.1 GO:0000322 storage vacuole(GO:0000322)
0.1 8.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.7 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 230.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 7.8 GO:0005581 collagen trimer(GO:0005581)
0.1 6.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 2.2 GO:0005922 connexon complex(GO:0005922)
0.1 1.8 GO:0031526 brush border membrane(GO:0031526)
0.1 1.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.2 GO:0097449 glial cell projection(GO:0097386) astrocyte projection(GO:0097449)
0.1 7.3 GO:0043235 receptor complex(GO:0043235)
0.1 1.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 155.3 GO:0005615 extracellular space(GO:0005615)
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 2.0 GO:0031904 endosome lumen(GO:0031904)
0.1 6.7 GO:0016459 myosin complex(GO:0016459)
0.1 1.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 14.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 7.8 GO:0042383 sarcolemma(GO:0042383)
0.1 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.6 GO:0044294 dendritic growth cone(GO:0044294)
0.1 10.4 GO:0001650 fibrillar center(GO:0001650)
0.1 2.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.7 GO:0016235 aggresome(GO:0016235)
0.1 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 50.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 0.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 5.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 28.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 1.1 GO:0051233 spindle midzone(GO:0051233)
0.1 1.1 GO:0044447 axoneme part(GO:0044447)
0.1 1.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 13.3 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 4.6 GO:0030133 transport vesicle(GO:0030133)
0.0 2.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 4.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 3.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.1 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 5.2 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 93.2 GO:0005344 oxygen transporter activity(GO:0005344)
5.9 47.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
5.6 16.8 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
5.6 22.2 GO:0030492 hemoglobin binding(GO:0030492)
4.7 18.7 GO:0004998 transferrin receptor activity(GO:0004998)
4.0 11.9 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
3.8 15.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
3.7 11.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
3.6 21.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.5 10.4 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
3.4 99.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
2.5 12.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
2.3 18.3 GO:0004064 arylesterase activity(GO:0004064)
2.3 2.3 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
2.3 13.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
2.2 8.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
2.1 6.2 GO:0042015 interleukin-20 binding(GO:0042015)
2.1 12.3 GO:0004882 androgen receptor activity(GO:0004882)
2.0 7.9 GO:0004743 pyruvate kinase activity(GO:0004743)
1.9 5.8 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
1.9 15.3 GO:0030172 troponin C binding(GO:0030172)
1.8 12.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.8 7.1 GO:0016841 ammonia-lyase activity(GO:0016841)
1.8 5.3 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.6 4.8 GO:0019959 interleukin-8 binding(GO:0019959)
1.5 9.2 GO:0005499 vitamin D binding(GO:0005499)
1.5 4.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
1.4 22.6 GO:0070330 aromatase activity(GO:0070330)
1.4 35.8 GO:0004806 triglyceride lipase activity(GO:0004806)
1.3 15.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
1.3 29.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.2 17.9 GO:0015643 toxic substance binding(GO:0015643)
1.2 5.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.1 3.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.1 4.6 GO:0015265 urea channel activity(GO:0015265)
1.1 5.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.0 6.2 GO:0015057 thrombin receptor activity(GO:0015057)
1.0 4.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.0 45.4 GO:0050699 WW domain binding(GO:0050699)
1.0 3.0 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.0 9.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.0 2.9 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.0 10.5 GO:0051525 NFAT protein binding(GO:0051525)
0.9 3.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.9 3.5 GO:0070051 fibrinogen binding(GO:0070051)
0.9 4.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.9 5.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.8 5.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.8 4.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8 2.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.8 7.2 GO:0032190 acrosin binding(GO:0032190)
0.8 9.5 GO:0042301 phosphate ion binding(GO:0042301)
0.8 3.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.8 3.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.8 2.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.8 2.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.7 5.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.7 1.4 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.7 20.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.7 2.8 GO:0004803 transposase activity(GO:0004803)
0.7 2.8 GO:0005497 androgen binding(GO:0005497)
0.7 7.6 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.7 6.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7 12.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.7 2.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.7 33.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.7 2.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.6 3.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.6 1.8 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.6 12.7 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.6 3.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.6 8.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.6 3.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.6 5.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 4.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 10.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 3.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.5 1.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.5 4.0 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.5 2.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.5 23.0 GO:0015485 cholesterol binding(GO:0015485)
0.5 4.8 GO:0031433 telethonin binding(GO:0031433)
0.5 4.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.5 2.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.5 5.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.5 2.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 4.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.4 11.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4 1.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.4 3.8 GO:0004969 histamine receptor activity(GO:0004969)
0.4 2.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.4 37.9 GO:0005518 collagen binding(GO:0005518)
0.4 4.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.4 1.6 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.4 6.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.4 1.6 GO:0004948 calcitonin receptor activity(GO:0004948)
0.4 112.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 1.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 9.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 8.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.4 3.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 14.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 2.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.3 4.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 2.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 1.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 6.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.3 1.7 GO:0031013 troponin I binding(GO:0031013)
0.3 1.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 2.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 2.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3 1.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 12.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.3 5.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 5.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 30.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.3 3.9 GO:0004875 complement receptor activity(GO:0004875)
0.3 0.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 1.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.3 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 4.5 GO:0070513 death domain binding(GO:0070513)
0.3 2.0 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 1.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 3.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 2.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 2.0 GO:0034711 inhibin binding(GO:0034711)
0.2 0.7 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 0.7 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 2.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 3.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 6.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 2.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.7 GO:0000035 acyl binding(GO:0000035)
0.2 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 5.5 GO:0019825 oxygen binding(GO:0019825)
0.2 1.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 2.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 7.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 3.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 9.5 GO:0005272 sodium channel activity(GO:0005272)
0.2 1.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 1.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 1.6 GO:0015232 heme transporter activity(GO:0015232)
0.2 1.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 4.9 GO:0008198 ferrous iron binding(GO:0008198)
0.2 31.4 GO:0005178 integrin binding(GO:0005178)
0.2 3.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 6.1 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 1.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 16.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 3.1 GO:0005112 Notch binding(GO:0005112)
0.2 14.0 GO:0001618 virus receptor activity(GO:0001618)
0.2 8.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 3.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 14.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.7 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 1.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 2.1 GO:0015250 water channel activity(GO:0015250)
0.2 11.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 0.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 5.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 2.2 GO:0005243 gap junction channel activity(GO:0005243)
0.1 3.4 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 2.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.2 GO:0019864 IgG binding(GO:0019864)
0.1 1.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 1.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 4.8 GO:0042605 peptide antigen binding(GO:0042605)
0.1 2.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 1.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 4.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 3.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.6 GO:0098821 BMP receptor activity(GO:0098821)
0.1 13.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 7.5 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 53.8 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 4.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 8.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 0.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 2.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 2.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 7.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 6.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 36.6 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.1 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.9 GO:0048156 tau protein binding(GO:0048156)
0.1 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 3.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 5.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 4.8 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.6 GO:0031489 myosin V binding(GO:0031489)
0.1 1.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 2.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 5.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.7 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 4.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 5.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.5 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 PID ALK2 PATHWAY ALK2 signaling events
0.8 3.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.8 43.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.7 36.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.6 43.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 4.4 PID IL5 PATHWAY IL5-mediated signaling events
0.5 5.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.4 2.8 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.4 4.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 94.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 6.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 8.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.3 11.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 8.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.3 27.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 16.0 PID EPO PATHWAY EPO signaling pathway
0.2 12.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 7.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 13.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 11.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 6.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 6.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 8.1 NABA COLLAGENS Genes encoding collagen proteins
0.2 12.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 15.3 PID CMYB PATHWAY C-MYB transcription factor network
0.2 1.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 10.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.2 2.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 3.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 5.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 5.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 5.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 5.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 10.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 18.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 5.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 30.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 3.2 PID AP1 PATHWAY AP-1 transcription factor network
0.1 8.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.6 PID E2F PATHWAY E2F transcription factor network
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 38.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
1.8 47.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.7 41.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.6 66.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
1.5 21.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.9 16.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 15.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.7 24.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 24.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.7 9.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.6 10.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.6 16.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.6 18.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.6 4.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.6 2.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.6 96.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.6 15.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 7.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 43.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.5 18.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.5 5.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.5 43.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.5 10.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 3.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 6.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 26.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 4.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 4.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 14.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 4.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 7.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 9.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 8.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 4.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 4.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 4.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 5.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 3.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 2.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 1.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 2.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 4.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 6.0 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 4.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 6.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 2.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 11.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 7.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 5.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 11.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 4.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 5.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 6.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 3.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 2.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 3.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 0.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 3.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 5.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.3 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.0 1.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway