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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for GATA1_GATA4
Z-value: 0.50
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Transcription factors associated with GATA1_GATA4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
GATA1
|
ENSG00000102145.9 | GATA binding protein 1 |
|
GATA4
|
ENSG00000136574.13 | GATA binding protein 4 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GATA1 | hg19_v2_chrX_+_48644962_48644983 | 0.63 | 3.6e-25 | Click! |
| GATA4 | hg19_v2_chr8_+_11534462_11534475, hg19_v2_chr8_+_11561660_11561751 | 0.50 | 3.8e-15 | Click! |
Activity profile of GATA1_GATA4 motif
Sorted Z-values of GATA1_GATA4 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_-_43513187 | 47.01 |
ENST00000540029.1
ENST00000441366.2 |
EPB42
|
erythrocyte membrane protein band 4.2 |
| chr12_-_54689532 | 38.47 |
ENST00000540264.2
ENST00000312156.4 |
NFE2
|
nuclear factor, erythroid 2 |
| chr1_+_25598989 | 36.13 |
ENST00000454452.2
|
RHD
|
Rh blood group, D antigen |
| chr19_-_13213662 | 33.05 |
ENST00000264824.4
|
LYL1
|
lymphoblastic leukemia derived sequence 1 |
| chr10_-_99531709 | 28.36 |
ENST00000266066.3
|
SFRP5
|
secreted frizzled-related protein 5 |
| chr16_+_202686 | 27.39 |
ENST00000252951.2
|
HBZ
|
hemoglobin, zeta |
| chr19_-_12997995 | 24.79 |
ENST00000264834.4
|
KLF1
|
Kruppel-like factor 1 (erythroid) |
| chr11_-_5255861 | 24.70 |
ENST00000380299.3
|
HBD
|
hemoglobin, delta |
| chr10_+_118305435 | 23.47 |
ENST00000369221.2
|
PNLIP
|
pancreatic lipase |
| chr16_+_31539183 | 22.23 |
ENST00000302312.4
|
AHSP
|
alpha hemoglobin stabilizing protein |
| chr11_-_5271122 | 21.56 |
ENST00000330597.3
|
HBG1
|
hemoglobin, gamma A |
| chr6_+_41010293 | 20.63 |
ENST00000373161.1
ENST00000373158.2 ENST00000470917.1 |
TSPO2
|
translocator protein 2 |
| chr1_+_25599018 | 20.45 |
ENST00000417538.2
ENST00000357542.4 ENST00000568195.1 ENST00000342055.5 ENST00000423810.2 |
RHD
|
Rh blood group, D antigen |
| chr6_-_35765088 | 20.13 |
ENST00000259938.2
|
CLPS
|
colipase, pancreatic |
| chr1_-_25747283 | 19.55 |
ENST00000346452.4
ENST00000340849.4 ENST00000349438.4 ENST00000294413.7 ENST00000413854.1 ENST00000455194.1 ENST00000243186.6 ENST00000425135.1 |
RHCE
|
Rh blood group, CcEe antigens |
| chr11_-_5255696 | 19.51 |
ENST00000292901.3
ENST00000417377.1 |
HBD
|
hemoglobin, delta |
| chr7_-_100239132 | 18.70 |
ENST00000223051.3
ENST00000431692.1 |
TFR2
|
transferrin receptor 2 |
| chr8_-_86290333 | 18.33 |
ENST00000521846.1
ENST00000523022.1 ENST00000524324.1 ENST00000519991.1 ENST00000520663.1 ENST00000517590.1 ENST00000522579.1 ENST00000522814.1 ENST00000522662.1 ENST00000523858.1 ENST00000519129.1 |
CA1
|
carbonic anhydrase I |
| chr1_+_25598872 | 18.21 |
ENST00000328664.4
|
RHD
|
Rh blood group, D antigen |
| chr11_+_118958689 | 18.01 |
ENST00000535253.1
ENST00000392841.1 |
HMBS
|
hydroxymethylbilane synthase |
| chr19_-_11494975 | 17.82 |
ENST00000222139.6
ENST00000592375.2 |
EPOR
|
erythropoietin receptor |
| chr6_-_52628271 | 17.33 |
ENST00000493422.1
|
GSTA2
|
glutathione S-transferase alpha 2 |
| chrX_-_55057403 | 16.76 |
ENST00000396198.3
ENST00000335854.4 ENST00000455688.1 ENST00000330807.5 |
ALAS2
|
aminolevulinate, delta-, synthase 2 |
| chr4_-_144940477 | 15.84 |
ENST00000513128.1
ENST00000429670.2 ENST00000502664.1 |
GYPB
|
glycophorin B (MNS blood group) |
| chr19_-_55669093 | 15.26 |
ENST00000344887.5
|
TNNI3
|
troponin I type 3 (cardiac) |
| chr11_-_116708302 | 15.15 |
ENST00000375320.1
ENST00000359492.2 ENST00000375329.2 ENST00000375323.1 |
APOA1
|
apolipoprotein A-I |
| chr1_+_22303503 | 14.99 |
ENST00000337107.6
|
CELA3B
|
chymotrypsin-like elastase family, member 3B |
| chr12_-_114841703 | 14.99 |
ENST00000526441.1
|
TBX5
|
T-box 5 |
| chr1_+_22328144 | 14.95 |
ENST00000290122.3
ENST00000374663.1 |
CELA3A
|
chymotrypsin-like elastase family, member 3A |
| chr14_+_24584508 | 14.92 |
ENST00000559354.1
ENST00000560459.1 ENST00000559593.1 ENST00000396941.4 ENST00000396936.1 |
DCAF11
|
DDB1 and CUL4 associated factor 11 |
| chr7_+_130020180 | 14.90 |
ENST00000481342.1
ENST00000011292.3 ENST00000604896.1 |
CPA1
|
carboxypeptidase A1 (pancreatic) |
| chr19_+_10397621 | 14.09 |
ENST00000380770.3
|
ICAM4
|
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| chr17_-_47841485 | 14.08 |
ENST00000506156.1
ENST00000240364.2 |
FAM117A
|
family with sequence similarity 117, member A |
| chr1_-_158656488 | 13.69 |
ENST00000368147.4
|
SPTA1
|
spectrin, alpha, erythrocytic 1 (elliptocytosis 2) |
| chr7_-_150652924 | 13.65 |
ENST00000330883.4
|
KCNH2
|
potassium voltage-gated channel, subfamily H (eag-related), member 2 |
| chr11_+_128563652 | 13.16 |
ENST00000527786.2
|
FLI1
|
Fli-1 proto-oncogene, ETS transcription factor |
| chr14_-_21945057 | 13.04 |
ENST00000397762.1
|
RAB2B
|
RAB2B, member RAS oncogene family |
| chr19_+_10397648 | 12.97 |
ENST00000340992.4
ENST00000393717.2 |
ICAM4
|
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| chr7_+_80275621 | 12.42 |
ENST00000426978.1
ENST00000432207.1 |
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr7_-_99332719 | 12.31 |
ENST00000336374.2
|
CYP3A7
|
cytochrome P450, family 3, subfamily A, polypeptide 7 |
| chr1_-_153113927 | 11.70 |
ENST00000368752.4
|
SPRR2B
|
small proline-rich protein 2B |
| chr1_+_206317450 | 11.64 |
ENST00000358184.2
ENST00000361052.3 ENST00000360218.2 |
CTSE
|
cathepsin E |
| chr16_+_58283814 | 11.52 |
ENST00000443128.2
ENST00000219299.4 |
CCDC113
|
coiled-coil domain containing 113 |
| chr1_+_43291220 | 10.65 |
ENST00000372514.3
|
ERMAP
|
erythroblast membrane-associated protein (Scianna blood group) |
| chr6_-_30128657 | 10.47 |
ENST00000449742.2
ENST00000376704.3 |
TRIM10
|
tripartite motif containing 10 |
| chr1_+_161136180 | 10.09 |
ENST00000352210.5
ENST00000367999.4 ENST00000544598.1 ENST00000535223.1 ENST00000432542.2 |
PPOX
|
protoporphyrinogen oxidase |
| chr4_+_154387480 | 10.05 |
ENST00000409663.3
ENST00000440693.1 ENST00000409959.3 |
KIAA0922
|
KIAA0922 |
| chr12_-_120765565 | 9.81 |
ENST00000423423.3
ENST00000308366.4 |
PLA2G1B
|
phospholipase A2, group IB (pancreas) |
| chr4_-_72649763 | 9.75 |
ENST00000513476.1
|
GC
|
group-specific component (vitamin D binding protein) |
| chr1_+_205225319 | 9.68 |
ENST00000329800.7
|
TMCC2
|
transmembrane and coiled-coil domain family 2 |
| chr14_-_24584138 | 9.48 |
ENST00000558280.1
ENST00000561028.1 |
NRL
|
neural retina leucine zipper |
| chr8_-_41655107 | 9.29 |
ENST00000347528.4
ENST00000289734.7 ENST00000379758.2 ENST00000396945.1 ENST00000396942.1 ENST00000352337.4 |
ANK1
|
ankyrin 1, erythrocytic |
| chr4_+_74275057 | 9.27 |
ENST00000511370.1
|
ALB
|
albumin |
| chr9_+_33795533 | 9.18 |
ENST00000379405.3
|
PRSS3
|
protease, serine, 3 |
| chr7_+_80275752 | 9.12 |
ENST00000419819.2
|
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr7_-_99381884 | 8.86 |
ENST00000336411.2
|
CYP3A4
|
cytochrome P450, family 3, subfamily A, polypeptide 4 |
| chr6_-_33168391 | 8.77 |
ENST00000374685.4
ENST00000413614.2 ENST00000374680.3 |
RXRB
|
retinoid X receptor, beta |
| chr4_-_145061788 | 8.76 |
ENST00000512064.1
ENST00000512789.1 ENST00000504786.1 ENST00000503627.1 ENST00000535709.1 ENST00000324022.10 ENST00000360771.4 ENST00000283126.7 |
GYPA
GYPB
|
glycophorin A (MNS blood group) glycophorin B (MNS blood group) |
| chr3_-_119379427 | 8.69 |
ENST00000264231.3
ENST00000468801.1 ENST00000538678.1 |
POPDC2
|
popeye domain containing 2 |
| chr4_+_74269956 | 8.67 |
ENST00000295897.4
ENST00000415165.2 ENST00000503124.1 ENST00000509063.1 ENST00000401494.3 |
ALB
|
albumin |
| chr18_+_19749386 | 8.51 |
ENST00000269216.3
|
GATA6
|
GATA binding protein 6 |
| chr1_+_15783222 | 8.28 |
ENST00000359621.4
|
CELA2A
|
chymotrypsin-like elastase family, member 2A |
| chrX_-_65253506 | 8.05 |
ENST00000427538.1
|
VSIG4
|
V-set and immunoglobulin domain containing 4 |
| chr6_-_46889694 | 7.87 |
ENST00000283296.7
ENST00000362015.4 ENST00000456426.2 |
GPR116
|
G protein-coupled receptor 116 |
| chr16_-_75241050 | 7.84 |
ENST00000303037.8
|
CTRB2
|
chymotrypsinogen B2 |
| chr11_-_113746212 | 7.82 |
ENST00000537642.1
ENST00000537706.1 ENST00000544750.1 ENST00000260188.5 ENST00000540925.1 |
USP28
|
ubiquitin specific peptidase 28 |
| chr6_-_46048116 | 7.80 |
ENST00000185206.6
|
CLIC5
|
chloride intracellular channel 5 |
| chr12_-_91573132 | 7.76 |
ENST00000550563.1
ENST00000546370.1 |
DCN
|
decorin |
| chr2_+_3642545 | 7.75 |
ENST00000382062.2
ENST00000236693.7 ENST00000349077.4 |
COLEC11
|
collectin sub-family member 11 |
| chr4_-_74847800 | 7.60 |
ENST00000296029.3
|
PF4
|
platelet factor 4 |
| chr4_-_144826682 | 7.58 |
ENST00000358615.4
ENST00000437468.2 |
GYPE
|
glycophorin E (MNS blood group) |
| chr11_-_57158109 | 7.57 |
ENST00000525955.1
ENST00000533605.1 ENST00000311862.5 |
PRG2
|
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| chr7_+_142457315 | 7.47 |
ENST00000486171.1
ENST00000311737.7 |
PRSS1
|
protease, serine, 1 (trypsin 1) |
| chr2_+_234959376 | 7.42 |
ENST00000425558.1
|
SPP2
|
secreted phosphoprotein 2, 24kDa |
| chr12_-_6233828 | 7.39 |
ENST00000572068.1
ENST00000261405.5 |
VWF
|
von Willebrand factor |
| chrX_+_38211777 | 7.19 |
ENST00000039007.4
|
OTC
|
ornithine carbamoyltransferase |
| chr14_+_95047744 | 7.16 |
ENST00000553511.1
ENST00000554633.1 ENST00000555681.1 ENST00000554276.1 |
SERPINA5
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| chr3_-_58196688 | 7.11 |
ENST00000486455.1
|
DNASE1L3
|
deoxyribonuclease I-like 3 |
| chr1_-_27240455 | 6.91 |
ENST00000254227.3
|
NR0B2
|
nuclear receptor subfamily 0, group B, member 2 |
| chr12_-_15103621 | 6.88 |
ENST00000536592.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr17_-_29641084 | 6.85 |
ENST00000544462.1
|
EVI2B
|
ecotropic viral integration site 2B |
| chr14_+_102276192 | 6.83 |
ENST00000557714.1
|
PPP2R5C
|
protein phosphatase 2, regulatory subunit B', gamma |
| chr4_-_103266355 | 6.69 |
ENST00000424970.2
|
SLC39A8
|
solute carrier family 39 (zinc transporter), member 8 |
| chr17_+_37824217 | 6.66 |
ENST00000394246.1
|
PNMT
|
phenylethanolamine N-methyltransferase |
| chr1_-_201368707 | 6.64 |
ENST00000391967.2
|
LAD1
|
ladinin 1 |
| chr9_+_33240157 | 6.57 |
ENST00000379721.3
|
SPINK4
|
serine peptidase inhibitor, Kazal type 4 |
| chr17_+_41857793 | 6.53 |
ENST00000449302.3
|
C17orf105
|
chromosome 17 open reading frame 105 |
| chrX_+_128913906 | 6.50 |
ENST00000356892.3
|
SASH3
|
SAM and SH3 domain containing 3 |
| chr10_+_70847852 | 6.45 |
ENST00000242465.3
|
SRGN
|
serglycin |
| chr16_+_333152 | 6.40 |
ENST00000219406.6
ENST00000404312.1 ENST00000456379.1 |
PDIA2
|
protein disulfide isomerase family A, member 2 |
| chr8_-_20040601 | 6.39 |
ENST00000265808.7
ENST00000522513.1 |
SLC18A1
|
solute carrier family 18 (vesicular monoamine transporter), member 1 |
| chr16_+_71560154 | 6.36 |
ENST00000539698.3
|
CHST4
|
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| chr1_-_201368653 | 6.32 |
ENST00000367313.3
|
LAD1
|
ladinin 1 |
| chr16_+_71560023 | 6.28 |
ENST00000572450.1
|
CHST4
|
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| chr1_-_24469602 | 6.17 |
ENST00000270800.1
|
IL22RA1
|
interleukin 22 receptor, alpha 1 |
| chr10_+_96443204 | 6.00 |
ENST00000339022.5
|
CYP2C18
|
cytochrome P450, family 2, subfamily C, polypeptide 18 |
| chr1_-_54872059 | 5.99 |
ENST00000371320.3
|
SSBP3
|
single stranded DNA binding protein 3 |
| chr10_+_118350522 | 5.97 |
ENST00000530319.1
ENST00000527980.1 ENST00000471549.1 ENST00000534537.1 |
PNLIPRP1
|
pancreatic lipase-related protein 1 |
| chr2_+_79347577 | 5.88 |
ENST00000233735.1
|
REG1A
|
regenerating islet-derived 1 alpha |
| chr17_-_64225508 | 5.83 |
ENST00000205948.6
|
APOH
|
apolipoprotein H (beta-2-glycoprotein I) |
| chr3_-_98312548 | 5.79 |
ENST00000264193.2
|
CPOX
|
coproporphyrinogen oxidase |
| chr1_-_175162048 | 5.79 |
ENST00000444639.1
|
KIAA0040
|
KIAA0040 |
| chr5_-_135290705 | 5.78 |
ENST00000274507.1
|
LECT2
|
leukocyte cell-derived chemotaxin 2 |
| chr2_+_220379052 | 5.75 |
ENST00000347842.3
ENST00000358078.4 |
ASIC4
|
acid-sensing (proton-gated) ion channel family member 4 |
| chr1_+_199996702 | 5.74 |
ENST00000367362.3
|
NR5A2
|
nuclear receptor subfamily 5, group A, member 2 |
| chr12_-_14996355 | 5.70 |
ENST00000228936.4
|
ART4
|
ADP-ribosyltransferase 4 (Dombrock blood group) |
| chr11_-_1036706 | 5.62 |
ENST00000421673.2
|
MUC6
|
mucin 6, oligomeric mucus/gel-forming |
| chr17_+_4675175 | 5.62 |
ENST00000270560.3
|
TM4SF5
|
transmembrane 4 L six family member 5 |
| chr5_-_141061777 | 5.61 |
ENST00000239440.4
|
ARAP3
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| chr17_+_4835580 | 5.56 |
ENST00000329125.5
|
GP1BA
|
glycoprotein Ib (platelet), alpha polypeptide |
| chr8_-_20040638 | 5.55 |
ENST00000519026.1
ENST00000276373.5 ENST00000440926.1 ENST00000437980.1 |
SLC18A1
|
solute carrier family 18 (vesicular monoamine transporter), member 1 |
| chr5_-_141061759 | 5.45 |
ENST00000508305.1
|
ARAP3
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| chr12_+_9102632 | 5.43 |
ENST00000539240.1
|
KLRG1
|
killer cell lectin-like receptor subfamily G, member 1 |
| chr10_+_118350468 | 5.35 |
ENST00000358834.4
ENST00000528052.1 ENST00000442761.1 |
PNLIPRP1
|
pancreatic lipase-related protein 1 |
| chr7_-_99277610 | 5.33 |
ENST00000343703.5
ENST00000222982.4 ENST00000439761.1 ENST00000339843.2 |
CYP3A5
|
cytochrome P450, family 3, subfamily A, polypeptide 5 |
| chr12_-_10151773 | 5.28 |
ENST00000298527.6
ENST00000348658.4 |
CLEC1B
|
C-type lectin domain family 1, member B |
| chr19_+_1041212 | 5.26 |
ENST00000433129.1
|
ABCA7
|
ATP-binding cassette, sub-family A (ABC1), member 7 |
| chr16_+_67840668 | 5.25 |
ENST00000415766.3
|
TSNAXIP1
|
translin-associated factor X interacting protein 1 |
| chr12_-_91573249 | 5.15 |
ENST00000550099.1
ENST00000546391.1 ENST00000551354.1 |
DCN
|
decorin |
| chr14_-_23877474 | 5.12 |
ENST00000405093.3
|
MYH6
|
myosin, heavy chain 6, cardiac muscle, alpha |
| chr2_-_88427568 | 5.10 |
ENST00000393750.3
ENST00000295834.3 |
FABP1
|
fatty acid binding protein 1, liver |
| chr10_+_74451883 | 5.08 |
ENST00000373053.3
ENST00000357157.6 |
MCU
|
mitochondrial calcium uniporter |
| chr2_+_234959323 | 5.04 |
ENST00000373368.1
ENST00000168148.3 |
SPP2
|
secreted phosphoprotein 2, 24kDa |
| chr11_+_10477733 | 4.96 |
ENST00000528723.1
|
AMPD3
|
adenosine monophosphate deaminase 3 |
| chr1_+_198608146 | 4.96 |
ENST00000367376.2
ENST00000352140.3 ENST00000594404.1 ENST00000598951.1 ENST00000530727.1 ENST00000442510.2 ENST00000367367.4 ENST00000348564.6 ENST00000367364.1 ENST00000413409.2 |
PTPRC
|
protein tyrosine phosphatase, receptor type, C |
| chr19_-_51522955 | 4.94 |
ENST00000358789.3
|
KLK10
|
kallikrein-related peptidase 10 |
| chr12_+_32655048 | 4.87 |
ENST00000427716.2
ENST00000266482.3 |
FGD4
|
FYVE, RhoGEF and PH domain containing 4 |
| chr19_+_36132631 | 4.84 |
ENST00000379026.2
ENST00000379023.4 ENST00000402764.2 ENST00000479824.1 |
ETV2
|
ets variant 2 |
| chr12_-_9268707 | 4.83 |
ENST00000318602.7
|
A2M
|
alpha-2-macroglobulin |
| chr6_-_32498046 | 4.80 |
ENST00000374975.3
|
HLA-DRB5
|
major histocompatibility complex, class II, DR beta 5 |
| chr2_-_89459813 | 4.71 |
ENST00000390256.2
|
IGKV6-21
|
immunoglobulin kappa variable 6-21 (non-functional) |
| chr4_-_186697044 | 4.70 |
ENST00000437304.2
|
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr10_-_104597286 | 4.68 |
ENST00000369887.3
|
CYP17A1
|
cytochrome P450, family 17, subfamily A, polypeptide 1 |
| chr5_+_59783941 | 4.66 |
ENST00000506884.1
ENST00000504876.2 |
PART1
|
prostate androgen-regulated transcript 1 (non-protein coding) |
| chr2_+_189156638 | 4.63 |
ENST00000410051.1
|
GULP1
|
GULP, engulfment adaptor PTB domain containing 1 |
| chr1_+_22351977 | 4.62 |
ENST00000420503.1
ENST00000416769.1 ENST00000404210.2 |
LINC00339
|
long intergenic non-protein coding RNA 339 |
| chr19_-_51568324 | 4.60 |
ENST00000595547.1
ENST00000335422.3 ENST00000595793.1 ENST00000596955.1 |
KLK13
|
kallikrein-related peptidase 13 |
| chr2_+_103035102 | 4.58 |
ENST00000264260.2
|
IL18RAP
|
interleukin 18 receptor accessory protein |
| chr15_-_58306295 | 4.57 |
ENST00000559517.1
|
ALDH1A2
|
aldehyde dehydrogenase 1 family, member A2 |
| chr1_-_155270770 | 4.55 |
ENST00000392414.3
|
PKLR
|
pyruvate kinase, liver and RBC |
| chr12_-_96390063 | 4.55 |
ENST00000541929.1
|
HAL
|
histidine ammonia-lyase |
| chr5_+_140480083 | 4.53 |
ENST00000231130.2
|
PCDHB3
|
protocadherin beta 3 |
| chr12_+_94071341 | 4.49 |
ENST00000542893.2
|
CRADD
|
CASP2 and RIPK1 domain containing adaptor with death domain |
| chr9_-_124132483 | 4.48 |
ENST00000286713.2
ENST00000538954.1 ENST00000347359.2 |
STOM
|
stomatin |
| chr22_-_29784519 | 4.43 |
ENST00000357586.2
ENST00000356015.2 ENST00000432560.2 ENST00000317368.7 |
AP1B1
|
adaptor-related protein complex 1, beta 1 subunit |
| chr6_+_7108210 | 4.39 |
ENST00000467782.1
ENST00000334984.6 ENST00000349384.6 |
RREB1
|
ras responsive element binding protein 1 |
| chr11_-_64684672 | 4.29 |
ENST00000377264.3
ENST00000421419.2 |
ATG2A
|
autophagy related 2A |
| chr3_-_187009646 | 4.27 |
ENST00000296280.6
ENST00000392470.2 ENST00000169293.6 ENST00000439271.1 ENST00000392472.2 ENST00000392475.2 |
MASP1
|
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| chr19_-_51487071 | 4.26 |
ENST00000391807.1
ENST00000593904.1 |
KLK7
|
kallikrein-related peptidase 7 |
| chr6_-_150039249 | 4.25 |
ENST00000543571.1
|
LATS1
|
large tumor suppressor kinase 1 |
| chr6_-_87804815 | 4.23 |
ENST00000369582.2
|
CGA
|
glycoprotein hormones, alpha polypeptide |
| chr11_-_125550764 | 4.19 |
ENST00000527795.1
|
ACRV1
|
acrosomal vesicle protein 1 |
| chr2_-_228028829 | 4.16 |
ENST00000396625.3
ENST00000329662.7 |
COL4A4
|
collagen, type IV, alpha 4 |
| chr11_-_85393886 | 4.15 |
ENST00000534224.1
|
CREBZF
|
CREB/ATF bZIP transcription factor |
| chr1_-_120311517 | 4.14 |
ENST00000369406.3
ENST00000544913.2 |
HMGCS2
|
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
| chr1_-_153029980 | 4.14 |
ENST00000392653.2
|
SPRR2A
|
small proline-rich protein 2A |
| chr14_+_22977587 | 4.13 |
ENST00000390504.1
|
TRAJ33
|
T cell receptor alpha joining 33 |
| chr9_-_97356075 | 4.10 |
ENST00000375337.3
|
FBP2
|
fructose-1,6-bisphosphatase 2 |
| chr15_-_34610962 | 4.10 |
ENST00000290209.5
|
SLC12A6
|
solute carrier family 12 (potassium/chloride transporter), member 6 |
| chr8_-_72274467 | 4.09 |
ENST00000340726.3
|
EYA1
|
eyes absent homolog 1 (Drosophila) |
| chr19_-_51327034 | 4.09 |
ENST00000301420.2
ENST00000448701.2 |
KLK1
|
kallikrein 1 |
| chr11_+_128563948 | 4.08 |
ENST00000534087.2
|
FLI1
|
Fli-1 proto-oncogene, ETS transcription factor |
| chr3_+_48264816 | 4.08 |
ENST00000296435.2
ENST00000576243.1 |
CAMP
|
cathelicidin antimicrobial peptide |
| chr14_-_65409438 | 4.06 |
ENST00000557049.1
|
GPX2
|
glutathione peroxidase 2 (gastrointestinal) |
| chr14_+_60975644 | 4.06 |
ENST00000327720.5
|
SIX6
|
SIX homeobox 6 |
| chr6_-_52710893 | 4.05 |
ENST00000284562.2
|
GSTA5
|
glutathione S-transferase alpha 5 |
| chr1_-_153013588 | 3.94 |
ENST00000360379.3
|
SPRR2D
|
small proline-rich protein 2D |
| chr3_-_58196939 | 3.94 |
ENST00000394549.2
ENST00000461914.3 |
DNASE1L3
|
deoxyribonuclease I-like 3 |
| chr19_-_4066890 | 3.93 |
ENST00000322357.4
|
ZBTB7A
|
zinc finger and BTB domain containing 7A |
| chr2_-_89619904 | 3.93 |
ENST00000498574.1
|
IGKV1-39
|
immunoglobulin kappa variable 1-39 (gene/pseudogene) |
| chr8_+_21823726 | 3.91 |
ENST00000433566.4
|
XPO7
|
exportin 7 |
| chr7_+_100318423 | 3.88 |
ENST00000252723.2
|
EPO
|
erythropoietin |
| chr12_-_8218997 | 3.87 |
ENST00000307637.4
|
C3AR1
|
complement component 3a receptor 1 |
| chr10_-_52645416 | 3.87 |
ENST00000374001.2
ENST00000373997.3 ENST00000373995.3 ENST00000282641.2 ENST00000395495.1 ENST00000414883.1 |
A1CF
|
APOBEC1 complementation factor |
| chr2_+_170366203 | 3.85 |
ENST00000284669.1
|
KLHL41
|
kelch-like family member 41 |
| chr6_-_27840099 | 3.84 |
ENST00000328488.2
|
HIST1H3I
|
histone cluster 1, H3i |
| chr8_+_121137333 | 3.80 |
ENST00000309791.4
ENST00000297848.3 ENST00000247781.3 |
COL14A1
|
collagen, type XIV, alpha 1 |
| chr4_+_78432907 | 3.78 |
ENST00000286758.4
|
CXCL13
|
chemokine (C-X-C motif) ligand 13 |
| chr17_+_37824411 | 3.76 |
ENST00000269582.2
|
PNMT
|
phenylethanolamine N-methyltransferase |
| chr14_-_21566731 | 3.76 |
ENST00000360947.3
|
ZNF219
|
zinc finger protein 219 |
| chr19_+_35739897 | 3.72 |
ENST00000605618.1
ENST00000427250.1 ENST00000601623.1 |
LSR
|
lipolysis stimulated lipoprotein receptor |
| chr12_+_53818855 | 3.69 |
ENST00000550839.1
|
AMHR2
|
anti-Mullerian hormone receptor, type II |
| chr14_-_90798418 | 3.67 |
ENST00000354366.3
|
NRDE2
|
NRDE-2, necessary for RNA interference, domain containing |
| chr5_+_121647764 | 3.66 |
ENST00000261368.8
ENST00000379533.2 ENST00000379536.2 ENST00000379538.3 |
SNCAIP
|
synuclein, alpha interacting protein |
| chr2_-_100721923 | 3.66 |
ENST00000356421.2
|
AFF3
|
AF4/FMR2 family, member 3 |
| chr11_-_47374246 | 3.62 |
ENST00000545968.1
ENST00000399249.2 ENST00000256993.4 |
MYBPC3
|
myosin binding protein C, cardiac |
| chr11_-_64510409 | 3.61 |
ENST00000394429.1
ENST00000394428.1 |
RASGRP2
|
RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| chr7_+_39125365 | 3.61 |
ENST00000559001.1
ENST00000464276.2 |
POU6F2
|
POU class 6 homeobox 2 |
| chr8_-_93107827 | 3.61 |
ENST00000520724.1
ENST00000518844.1 |
RUNX1T1
|
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| chr15_+_41136216 | 3.59 |
ENST00000562057.1
ENST00000344051.4 |
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chr6_+_7107830 | 3.58 |
ENST00000379933.3
|
RREB1
|
ras responsive element binding protein 1 |
| chr21_-_37852359 | 3.58 |
ENST00000399137.1
ENST00000399135.1 |
CLDN14
|
claudin 14 |
| chr15_-_64126084 | 3.56 |
ENST00000560316.1
ENST00000443617.2 ENST00000560462.1 ENST00000558532.1 ENST00000561400.1 |
HERC1
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
| chr10_+_114710425 | 3.55 |
ENST00000352065.5
ENST00000369395.1 |
TCF7L2
|
transcription factor 7-like 2 (T-cell specific, HMG-box) |
| chr17_-_42466864 | 3.55 |
ENST00000353281.4
ENST00000262407.5 |
ITGA2B
|
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| chr1_+_171217622 | 3.53 |
ENST00000433267.1
ENST00000367750.3 |
FMO1
|
flavin containing monooxygenase 1 |
| chr15_-_34628951 | 3.50 |
ENST00000397707.2
ENST00000560611.1 |
SLC12A6
|
solute carrier family 12 (potassium/chloride transporter), member 6 |
| chr6_+_31582961 | 3.50 |
ENST00000376059.3
ENST00000337917.7 |
AIF1
|
allograft inflammatory factor 1 |
| chr4_-_103266219 | 3.50 |
ENST00000394833.2
|
SLC39A8
|
solute carrier family 39 (zinc transporter), member 8 |
| chr4_-_68749745 | 3.50 |
ENST00000283916.6
|
TMPRSS11D
|
transmembrane protease, serine 11D |
Network of associatons between targets according to the STRING database.
First level regulatory network of GATA1_GATA4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.2 | 21.7 | GO:0038162 | erythropoietin-mediated signaling pathway(GO:0038162) |
| 7.1 | 28.4 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
| 6.8 | 74.4 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 6.0 | 17.9 | GO:0044179 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 5.0 | 15.0 | GO:0003218 | cardiac left ventricle formation(GO:0003218) |
| 4.7 | 65.8 | GO:0015671 | oxygen transport(GO:0015671) |
| 4.5 | 13.6 | GO:1902303 | regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303) |
| 4.5 | 18.2 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
| 3.8 | 15.1 | GO:0010903 | negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) |
| 3.7 | 48.4 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 3.4 | 77.8 | GO:0044241 | lipid digestion(GO:0044241) |
| 3.1 | 18.7 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 3.1 | 99.1 | GO:0015695 | organic cation transport(GO:0015695) |
| 3.1 | 12.3 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 2.9 | 29.1 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 2.8 | 8.5 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 2.6 | 10.4 | GO:0042418 | epinephrine biosynthetic process(GO:0042418) |
| 2.6 | 10.4 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 2.4 | 7.2 | GO:0070781 | arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781) |
| 2.4 | 11.9 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 2.4 | 7.1 | GO:0043606 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 2.4 | 9.5 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 2.2 | 6.5 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 2.1 | 8.3 | GO:0002215 | defense response to nematode(GO:0002215) |
| 1.9 | 15.1 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 1.9 | 5.6 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 1.8 | 8.9 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 1.8 | 7.1 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 1.8 | 5.3 | GO:1902995 | regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) |
| 1.7 | 6.9 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 1.7 | 6.9 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 1.6 | 11.1 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 1.5 | 7.6 | GO:0042539 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 1.5 | 4.4 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 1.5 | 4.4 | GO:0038043 | interleukin-5-mediated signaling pathway(GO:0038043) |
| 1.5 | 2.9 | GO:0018894 | dibenzo-p-dioxin metabolic process(GO:0018894) |
| 1.4 | 7.2 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 1.4 | 7.1 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 1.4 | 24.2 | GO:0020027 | hemoglobin metabolic process(GO:0020027) |
| 1.4 | 12.6 | GO:0006477 | protein sulfation(GO:0006477) |
| 1.4 | 17.9 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 1.3 | 16.0 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 1.3 | 5.3 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 1.3 | 7.9 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 1.3 | 3.8 | GO:2001027 | negative regulation of endothelial cell chemotaxis(GO:2001027) |
| 1.2 | 3.6 | GO:0048867 | stem cell fate determination(GO:0048867) |
| 1.2 | 30.0 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 1.1 | 6.6 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
| 1.1 | 6.4 | GO:0010909 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 1.1 | 5.3 | GO:0032971 | regulation of muscle filament sliding(GO:0032971) |
| 1.1 | 1.1 | GO:0002784 | regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) |
| 1.0 | 22.0 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 1.0 | 4.1 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 1.0 | 10.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 1.0 | 3.0 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 1.0 | 5.0 | GO:0048539 | immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539) |
| 1.0 | 2.9 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 1.0 | 4.8 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 1.0 | 4.8 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
| 0.9 | 24.7 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.9 | 3.7 | GO:1902613 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 0.9 | 4.6 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.9 | 2.7 | GO:1901624 | negative regulation of lymphocyte chemotaxis(GO:1901624) |
| 0.9 | 2.7 | GO:0086092 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 0.9 | 2.7 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.9 | 3.5 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) |
| 0.9 | 2.6 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
| 0.9 | 17.2 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.9 | 3.4 | GO:0090107 | regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 0.9 | 6.0 | GO:0021999 | neural plate anterior/posterior regionalization(GO:0021999) |
| 0.8 | 4.2 | GO:0001826 | inner cell mass cell differentiation(GO:0001826) |
| 0.8 | 5.1 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.8 | 2.5 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.8 | 7.6 | GO:0055009 | atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009) |
| 0.8 | 2.5 | GO:0003285 | septum secundum development(GO:0003285) |
| 0.8 | 5.0 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.8 | 4.8 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822) |
| 0.8 | 7.8 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
| 0.8 | 2.3 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.8 | 3.1 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 0.8 | 2.3 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 0.7 | 3.7 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 0.7 | 3.0 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.7 | 2.2 | GO:1903487 | regulation of lactation(GO:1903487) |
| 0.7 | 3.5 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.7 | 2.7 | GO:0051935 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
| 0.7 | 2.0 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.6 | 3.9 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.6 | 4.5 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.6 | 3.2 | GO:0072248 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
| 0.6 | 5.1 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.6 | 2.5 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.6 | 3.1 | GO:1900019 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.6 | 11.6 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.6 | 4.9 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.6 | 2.4 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 0.6 | 5.4 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.6 | 1.8 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.6 | 1.8 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 0.6 | 2.4 | GO:0072166 | posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) |
| 0.6 | 2.9 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 0.6 | 6.4 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.6 | 11.0 | GO:0010623 | programmed cell death involved in cell development(GO:0010623) |
| 0.6 | 2.3 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.6 | 2.3 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
| 0.6 | 2.2 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.5 | 13.7 | GO:0033014 | porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014) |
| 0.5 | 1.1 | GO:0060335 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.5 | 1.1 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
| 0.5 | 9.3 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.5 | 17.3 | GO:1901687 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.5 | 5.1 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.5 | 4.0 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.5 | 3.8 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.5 | 15.2 | GO:0010882 | regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882) |
| 0.5 | 2.4 | GO:2001033 | negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033) |
| 0.5 | 0.9 | GO:0070428 | regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) |
| 0.5 | 22.6 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.5 | 2.3 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.5 | 1.8 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
| 0.5 | 1.4 | GO:2000830 | vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830) |
| 0.4 | 1.3 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.4 | 2.2 | GO:0006581 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) |
| 0.4 | 1.3 | GO:0034653 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
| 0.4 | 9.7 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.4 | 1.8 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.4 | 1.3 | GO:0018874 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 0.4 | 6.5 | GO:0006702 | androgen biosynthetic process(GO:0006702) |
| 0.4 | 21.4 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.4 | 1.6 | GO:2000317 | negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
| 0.4 | 1.2 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.4 | 1.2 | GO:0044332 | Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) |
| 0.4 | 4.1 | GO:0051873 | killing by host of symbiont cells(GO:0051873) |
| 0.4 | 5.7 | GO:0006525 | arginine metabolic process(GO:0006525) |
| 0.4 | 6.5 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.4 | 10.5 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.4 | 8.0 | GO:0032703 | negative regulation of interleukin-2 production(GO:0032703) |
| 0.4 | 26.8 | GO:0060135 | maternal process involved in female pregnancy(GO:0060135) |
| 0.4 | 2.0 | GO:0071503 | response to heparin(GO:0071503) cellular response to heparin(GO:0071504) |
| 0.4 | 5.1 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.4 | 5.5 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.4 | 3.1 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.4 | 3.5 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.4 | 3.1 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.4 | 3.1 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 0.4 | 3.1 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.4 | 1.1 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.3 | 1.0 | GO:0003266 | regulation of secondary heart field cardioblast proliferation(GO:0003266) |
| 0.3 | 1.0 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726) |
| 0.3 | 4.1 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.3 | 3.4 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.3 | 2.0 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.3 | 2.0 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.3 | 3.3 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.3 | 5.3 | GO:0030220 | platelet formation(GO:0030220) |
| 0.3 | 2.0 | GO:2000807 | regulation of presynaptic membrane organization(GO:1901629) regulation of synaptic vesicle clustering(GO:2000807) |
| 0.3 | 2.3 | GO:0039663 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
| 0.3 | 1.3 | GO:0002884 | type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884) |
| 0.3 | 1.9 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.3 | 3.9 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.3 | 1.6 | GO:0015886 | heme transport(GO:0015886) |
| 0.3 | 1.6 | GO:0097461 | ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.3 | 0.6 | GO:2000015 | regulation of determination of dorsal identity(GO:2000015) |
| 0.3 | 1.6 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.3 | 0.9 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.3 | 2.5 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.3 | 2.8 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.3 | 5.9 | GO:0044705 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
| 0.3 | 4.6 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.3 | 2.3 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
| 0.3 | 3.6 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.3 | 2.6 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.3 | 1.6 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.3 | 3.9 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.3 | 2.0 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.3 | 2.8 | GO:0015074 | DNA integration(GO:0015074) |
| 0.3 | 5.3 | GO:0090083 | regulation of inclusion body assembly(GO:0090083) |
| 0.2 | 2.5 | GO:0051607 | defense response to virus(GO:0051607) |
| 0.2 | 1.0 | GO:0072660 | positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.2 | 1.6 | GO:0045007 | depurination(GO:0045007) |
| 0.2 | 0.7 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 0.2 | 0.5 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.2 | 2.7 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
| 0.2 | 2.4 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.2 | 2.0 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.2 | 1.5 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
| 0.2 | 3.0 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.2 | 1.2 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.2 | 1.0 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.2 | 1.4 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.2 | 1.6 | GO:0009744 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.2 | 3.6 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.2 | 1.5 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.2 | 1.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.2 | 3.4 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.2 | 2.2 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.2 | 4.3 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.2 | 0.6 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.2 | 2.0 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.2 | 2.0 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.2 | 3.2 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.2 | 3.6 | GO:2000178 | negative regulation of neural precursor cell proliferation(GO:2000178) |
| 0.2 | 1.4 | GO:0042060 | wound healing(GO:0042060) |
| 0.2 | 1.6 | GO:0046856 | phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.2 | 2.9 | GO:0019374 | galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) |
| 0.2 | 1.4 | GO:0001865 | NK T cell differentiation(GO:0001865) |
| 0.2 | 8.4 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.2 | 1.7 | GO:0035655 | interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351) |
| 0.2 | 2.8 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.2 | 0.5 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.2 | 1.5 | GO:0021853 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.2 | 4.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.2 | 4.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.2 | 3.7 | GO:0016246 | RNA interference(GO:0016246) |
| 0.2 | 1.4 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 0.2 | 0.3 | GO:0051597 | response to methylmercury(GO:0051597) |
| 0.2 | 11.2 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.2 | 1.7 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.1 | 3.4 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.1 | 2.4 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.1 | 13.3 | GO:0046849 | bone remodeling(GO:0046849) |
| 0.1 | 1.2 | GO:0071600 | otic vesicle morphogenesis(GO:0071600) |
| 0.1 | 1.0 | GO:0030856 | regulation of epithelial cell differentiation(GO:0030856) |
| 0.1 | 0.7 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
| 0.1 | 5.1 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 3.6 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.1 | 3.8 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.1 | 7.4 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 12.2 | GO:0046718 | viral entry into host cell(GO:0046718) |
| 0.1 | 5.5 | GO:0007099 | centriole replication(GO:0007099) |
| 0.1 | 1.2 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.1 | 4.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 1.9 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.1 | 0.7 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.1 | 0.8 | GO:0002924 | negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890) negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) |
| 0.1 | 1.2 | GO:0042249 | establishment of planar polarity of embryonic epithelium(GO:0042249) |
| 0.1 | 1.2 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.1 | 6.3 | GO:0042982 | amyloid precursor protein metabolic process(GO:0042982) |
| 0.1 | 1.4 | GO:0003084 | positive regulation of systemic arterial blood pressure(GO:0003084) |
| 0.1 | 1.6 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.1 | 6.2 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
| 0.1 | 1.1 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) regulation of GTP binding(GO:1904424) |
| 0.1 | 1.2 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.1 | 2.1 | GO:0006833 | water transport(GO:0006833) |
| 0.1 | 0.4 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 0.1 | 0.1 | GO:0060448 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
| 0.1 | 14.7 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
| 0.1 | 4.8 | GO:0045652 | regulation of megakaryocyte differentiation(GO:0045652) |
| 0.1 | 1.1 | GO:0060438 | trachea development(GO:0060438) |
| 0.1 | 0.5 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.1 | 1.6 | GO:0034332 | adherens junction organization(GO:0034332) |
| 0.1 | 2.0 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.1 | 2.7 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.1 | 3.4 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.1 | 1.8 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 1.2 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 0.6 | GO:0031124 | mRNA 3'-end processing(GO:0031124) |
| 0.1 | 4.5 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.1 | 0.6 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.1 | 3.1 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.7 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.1 | 2.6 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.1 | 1.9 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.1 | 2.0 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.1 | 1.0 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.1 | 1.1 | GO:0090312 | positive regulation of protein deacetylation(GO:0090312) |
| 0.1 | 4.3 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 2.3 | GO:0030239 | myofibril assembly(GO:0030239) |
| 0.1 | 15.7 | GO:0016567 | protein ubiquitination(GO:0016567) |
| 0.1 | 0.7 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.1 | 2.2 | GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947) |
| 0.1 | 1.3 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 2.1 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.1 | 1.6 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.1 | 6.1 | GO:1990748 | cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748) |
| 0.1 | 1.3 | GO:0030155 | regulation of cell adhesion(GO:0030155) |
| 0.1 | 3.5 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.1 | 7.6 | GO:0030449 | regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257) |
| 0.1 | 1.4 | GO:0001501 | skeletal system development(GO:0001501) |
| 0.1 | 3.4 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 0.1 | 4.6 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.1 | 0.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 0.7 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.1 | 0.3 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.1 | 3.2 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.1 | 4.3 | GO:0034644 | cellular response to UV(GO:0034644) |
| 0.1 | 1.1 | GO:0051255 | spindle midzone assembly(GO:0051255) |
| 0.1 | 1.9 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 1.3 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 3.4 | GO:0002027 | regulation of heart rate(GO:0002027) |
| 0.1 | 2.7 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.1 | 0.9 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.1 | 1.2 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.1 | 0.1 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.1 | 1.9 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.1 | 1.2 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.1 | 0.6 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.1 | 0.2 | GO:0046512 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
| 0.1 | 0.4 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.1 | 4.2 | GO:0045814 | negative regulation of gene expression, epigenetic(GO:0045814) |
| 0.1 | 1.6 | GO:0031018 | endocrine pancreas development(GO:0031018) |
| 0.0 | 0.6 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 1.9 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 0.5 | GO:0032354 | response to follicle-stimulating hormone(GO:0032354) |
| 0.0 | 0.6 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
| 0.0 | 2.5 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.0 | 1.8 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 3.5 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 3.9 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
| 0.0 | 0.6 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
| 0.0 | 2.6 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.2 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.0 | 6.7 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 4.8 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 2.6 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
| 0.0 | 0.1 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.0 | 2.4 | GO:0031214 | biomineral tissue development(GO:0031214) |
| 0.0 | 0.5 | GO:0010039 | response to iron ion(GO:0010039) |
| 0.0 | 0.7 | GO:0046427 | positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894) |
| 0.0 | 1.1 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 2.9 | GO:0046546 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.0 | 0.8 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 3.1 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 0.8 | GO:0030324 | lung development(GO:0030324) |
| 0.0 | 1.0 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.4 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.7 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.0 | 0.3 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.0 | 0.9 | GO:0006954 | inflammatory response(GO:0006954) |
| 0.0 | 0.1 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.9 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 1.0 | GO:0031294 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
| 0.0 | 0.3 | GO:0010762 | regulation of fibroblast migration(GO:0010762) |
| 0.0 | 1.8 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.4 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.0 | 1.1 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.5 | GO:0032760 | positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557) |
| 0.0 | 1.1 | GO:0007498 | mesoderm development(GO:0007498) |
| 0.0 | 3.3 | GO:0050900 | leukocyte migration(GO:0050900) |
| 0.0 | 0.9 | GO:2000278 | regulation of DNA biosynthetic process(GO:2000278) |
| 0.0 | 3.1 | GO:0030198 | extracellular matrix organization(GO:0030198) |
| 0.0 | 0.4 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.0 | 0.9 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 0.0 | 0.7 | GO:0006024 | aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.0 | 1.9 | GO:0016042 | lipid catabolic process(GO:0016042) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.6 | 106.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 5.0 | 15.1 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 2.8 | 16.9 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 2.7 | 13.6 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 2.5 | 7.6 | GO:0097679 | symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679) |
| 2.4 | 7.2 | GO:0097183 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 2.0 | 13.7 | GO:0032437 | cuticular plate(GO:0032437) |
| 1.8 | 7.4 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 1.4 | 18.7 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 1.3 | 5.3 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 1.3 | 3.9 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 1.3 | 5.1 | GO:1990246 | uniplex complex(GO:1990246) |
| 1.2 | 7.1 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 1.1 | 16.0 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 1.1 | 7.6 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 1.1 | 6.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 1.0 | 17.4 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 1.0 | 4.0 | GO:0038038 | G-protein coupled receptor homodimeric complex(GO:0038038) |
| 0.8 | 7.5 | GO:0070083 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
| 0.7 | 22.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.7 | 12.8 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.7 | 2.0 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.6 | 5.1 | GO:0045179 | apical cortex(GO:0045179) |
| 0.6 | 9.1 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.6 | 2.2 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.5 | 6.5 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.5 | 4.2 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.5 | 3.1 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.5 | 5.6 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.5 | 2.9 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.5 | 3.8 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 0.5 | 2.4 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.5 | 14.9 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.4 | 2.7 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.4 | 12.3 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.4 | 3.4 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.4 | 3.0 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.4 | 2.0 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.4 | 3.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.4 | 10.1 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.4 | 4.2 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.3 | 6.1 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.3 | 41.3 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
| 0.3 | 5.6 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.3 | 2.5 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.3 | 60.0 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.3 | 5.8 | GO:0032982 | myosin filament(GO:0032982) |
| 0.3 | 2.3 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.3 | 1.0 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.2 | 8.7 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.2 | 4.9 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.2 | 3.9 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 1.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.2 | 49.3 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.2 | 1.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.2 | 11.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.2 | 0.9 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.2 | 4.8 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.2 | 1.8 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.2 | 2.3 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.2 | 1.3 | GO:0002177 | manchette(GO:0002177) |
| 0.2 | 1.1 | GO:1990393 | 3M complex(GO:1990393) |
| 0.2 | 9.5 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.2 | 8.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.2 | 4.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.2 | 3.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.2 | 9.9 | GO:0005604 | basement membrane(GO:0005604) |
| 0.2 | 1.1 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.2 | 1.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 1.6 | GO:0030057 | desmosome(GO:0030057) |
| 0.2 | 8.5 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.2 | 1.3 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.2 | 7.3 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
| 0.2 | 2.2 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.2 | 2.6 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 7.8 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 5.3 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 1.1 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.1 | 8.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 3.4 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 0.7 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 2.7 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.1 | 230.6 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.1 | 7.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 6.0 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 2.2 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 1.8 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.1 | 1.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 1.1 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.1 | 0.2 | GO:0097449 | glial cell projection(GO:0097386) astrocyte projection(GO:0097449) |
| 0.1 | 7.3 | GO:0043235 | receptor complex(GO:0043235) |
| 0.1 | 1.9 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 155.3 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 0.4 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 2.0 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.1 | 6.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 1.6 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.1 | 14.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.1 | 7.8 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.1 | 1.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 1.3 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.1 | 0.6 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 10.4 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 2.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 2.7 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 4.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 50.3 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.1 | 0.9 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 1.7 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 5.4 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.1 | 28.0 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 1.1 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 1.1 | GO:0044447 | axoneme part(GO:0044447) |
| 0.1 | 1.6 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 1.1 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.7 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.0 | 13.3 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 1.3 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.4 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 1.8 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.9 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 4.6 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.0 | 2.3 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 4.7 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.6 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 3.6 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 0.1 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 5.2 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.2 | 93.2 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 5.9 | 47.0 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 5.6 | 16.8 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 5.6 | 22.2 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 4.7 | 18.7 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 4.0 | 11.9 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
| 3.8 | 15.1 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 3.7 | 11.1 | GO:0030343 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 3.6 | 21.5 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 3.5 | 10.4 | GO:0004603 | phenylethanolamine N-methyltransferase activity(GO:0004603) |
| 3.4 | 99.1 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 2.5 | 12.5 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 2.3 | 18.3 | GO:0004064 | arylesterase activity(GO:0004064) |
| 2.3 | 2.3 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 2.3 | 13.6 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 2.2 | 8.8 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 2.1 | 6.2 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 2.1 | 12.3 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 2.0 | 7.9 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 1.9 | 5.8 | GO:0050429 | calcium-dependent phospholipase C activity(GO:0050429) |
| 1.9 | 15.3 | GO:0030172 | troponin C binding(GO:0030172) |
| 1.8 | 12.6 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 1.8 | 7.1 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 1.8 | 5.3 | GO:0090556 | apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 1.6 | 4.8 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 1.5 | 9.2 | GO:0005499 | vitamin D binding(GO:0005499) |
| 1.5 | 4.4 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
| 1.4 | 22.6 | GO:0070330 | aromatase activity(GO:0070330) |
| 1.4 | 35.8 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 1.3 | 15.9 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 1.3 | 29.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 1.2 | 17.9 | GO:0015643 | toxic substance binding(GO:0015643) |
| 1.2 | 5.8 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 1.1 | 3.4 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 1.1 | 4.6 | GO:0015265 | urea channel activity(GO:0015265) |
| 1.1 | 5.7 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 1.0 | 6.2 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 1.0 | 4.1 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 1.0 | 45.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 1.0 | 3.0 | GO:0004796 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 1.0 | 9.8 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 1.0 | 2.9 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 1.0 | 10.5 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.9 | 3.7 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.9 | 3.5 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.9 | 4.4 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.9 | 5.1 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.8 | 5.0 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.8 | 4.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.8 | 2.4 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 0.8 | 7.2 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.8 | 9.5 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.8 | 3.9 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.8 | 3.1 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 0.8 | 2.3 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 0.8 | 2.3 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.7 | 5.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.7 | 1.4 | GO:0004945 | angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945) |
| 0.7 | 20.9 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.7 | 2.8 | GO:0004803 | transposase activity(GO:0004803) |
| 0.7 | 2.8 | GO:0005497 | androgen binding(GO:0005497) |
| 0.7 | 7.6 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.7 | 6.9 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.7 | 12.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.7 | 2.7 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.7 | 33.1 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.7 | 2.0 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.6 | 3.1 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.6 | 1.8 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.6 | 12.7 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.6 | 3.5 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.6 | 8.0 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.6 | 3.4 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.6 | 5.0 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.5 | 4.9 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.5 | 10.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.5 | 3.1 | GO:0030109 | HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) |
| 0.5 | 1.5 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.5 | 4.0 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.5 | 2.5 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.5 | 23.0 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.5 | 4.8 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.5 | 4.8 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.5 | 2.4 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.5 | 5.1 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.5 | 2.7 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.4 | 4.5 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.4 | 11.1 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.4 | 1.3 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 0.4 | 3.8 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.4 | 2.1 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.4 | 37.9 | GO:0005518 | collagen binding(GO:0005518) |
| 0.4 | 4.6 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.4 | 1.6 | GO:0032408 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 0.4 | 6.1 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.4 | 1.6 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.4 | 112.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.4 | 1.6 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.4 | 9.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.4 | 8.1 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
| 0.4 | 3.9 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.4 | 14.9 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.3 | 2.0 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.3 | 4.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.3 | 2.7 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.3 | 1.3 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.3 | 6.4 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.3 | 1.7 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.3 | 1.3 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.3 | 2.2 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.3 | 2.2 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.3 | 1.5 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.3 | 12.6 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.3 | 5.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.3 | 5.7 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.3 | 30.1 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.3 | 3.9 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.3 | 0.8 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.3 | 1.9 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.3 | 0.8 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.3 | 4.5 | GO:0070513 | death domain binding(GO:0070513) |
| 0.3 | 2.0 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.3 | 1.8 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.2 | 3.5 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.2 | 2.0 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.2 | 2.0 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.2 | 0.7 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.2 | 0.7 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.2 | 2.1 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.2 | 3.9 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.2 | 6.2 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 0.2 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.2 | 2.9 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.2 | 0.7 | GO:0000035 | acyl binding(GO:0000035) |
| 0.2 | 1.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.2 | 0.9 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.2 | 5.5 | GO:0019825 | oxygen binding(GO:0019825) |
| 0.2 | 1.1 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.2 | 2.3 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.2 | 7.9 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.2 | 3.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.2 | 9.5 | GO:0005272 | sodium channel activity(GO:0005272) |
| 0.2 | 1.2 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.2 | 1.0 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 0.2 | 1.6 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.2 | 1.6 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.2 | 4.9 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.2 | 31.4 | GO:0005178 | integrin binding(GO:0005178) |
| 0.2 | 3.5 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.2 | 6.1 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.2 | 1.0 | GO:0015252 | hydrogen ion channel activity(GO:0015252) |
| 0.2 | 1.9 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.2 | 16.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 3.1 | GO:0005112 | Notch binding(GO:0005112) |
| 0.2 | 14.0 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.2 | 8.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.2 | 3.5 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 1.0 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.2 | 14.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 1.2 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.2 | 0.7 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.2 | 1.3 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.2 | 2.1 | GO:0015250 | water channel activity(GO:0015250) |
| 0.2 | 11.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 0.9 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.2 | 5.7 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 2.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 3.4 | GO:0015106 | bicarbonate transmembrane transporter activity(GO:0015106) |
| 0.1 | 2.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.1 | 2.2 | GO:0019864 | IgG binding(GO:0019864) |
| 0.1 | 1.3 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.1 | 1.3 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.1 | 4.8 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.1 | 2.5 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.1 | 1.4 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.1 | 4.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 1.4 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 0.9 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.1 | 3.9 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 0.6 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.1 | 13.9 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.1 | 7.5 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
| 0.1 | 53.8 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 0.1 | 4.2 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.1 | 8.3 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
| 0.1 | 0.8 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.1 | 2.2 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.1 | 2.6 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 7.8 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 1.6 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 6.2 | GO:1990782 | protein tyrosine kinase binding(GO:1990782) |
| 0.1 | 36.6 | GO:0000987 | core promoter proximal region sequence-specific DNA binding(GO:0000987) |
| 0.1 | 1.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 0.9 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 0.7 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 3.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 1.9 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 2.1 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.1 | 1.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 5.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 2.3 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 4.8 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.1 | 0.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 1.6 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 1.5 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 1.4 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.1 | 2.6 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.1 | 0.2 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.1 | 0.3 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.0 | 5.6 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.7 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.0 | 0.6 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 1.0 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 4.0 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 5.7 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.4 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.5 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 0.6 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.4 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.2 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.0 | 2.5 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.6 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 1.5 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 3.7 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.8 | 3.2 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.8 | 43.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.7 | 36.0 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.6 | 43.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.5 | 4.4 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.5 | 5.9 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.4 | 2.8 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.4 | 4.1 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.4 | 94.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.3 | 6.9 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.3 | 8.8 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.3 | 11.9 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.3 | 8.8 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.3 | 27.0 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.2 | 16.0 | PID EPO PATHWAY | EPO signaling pathway |
| 0.2 | 12.5 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.2 | 7.1 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.2 | 13.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.2 | 11.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.2 | 6.5 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.2 | 6.0 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.2 | 8.1 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.2 | 12.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.2 | 15.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.2 | 1.9 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.2 | 10.3 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.2 | 2.9 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 3.1 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 2.6 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 5.0 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 2.0 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 5.3 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 5.4 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.1 | 5.5 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.1 | 10.0 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 18.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.7 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 1.6 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.1 | 5.3 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 2.1 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 2.8 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 30.8 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.1 | 0.3 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 1.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 3.2 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.1 | 8.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 2.3 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.1 | 0.6 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 1.3 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 1.3 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 1.2 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 0.9 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.6 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 2.2 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 1.0 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 2.0 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 2.8 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 1.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.9 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 1.6 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.1 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.7 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 1.0 | PID RAC1 PATHWAY | RAC1 signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 38.7 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 1.8 | 47.3 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 1.7 | 41.3 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 1.6 | 66.0 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 1.5 | 21.8 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.9 | 16.2 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.7 | 15.0 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.7 | 24.2 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.7 | 24.4 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.7 | 9.8 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.6 | 10.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.6 | 16.4 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.6 | 18.8 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.6 | 4.6 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.6 | 2.3 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.6 | 96.9 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.6 | 15.4 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.5 | 7.1 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.5 | 43.8 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.5 | 18.0 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.5 | 5.3 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.5 | 43.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.5 | 10.7 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.4 | 3.3 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.4 | 6.5 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.4 | 26.0 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.4 | 4.4 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.3 | 4.8 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.3 | 14.1 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.3 | 4.1 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.3 | 7.9 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.3 | 9.5 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.3 | 8.1 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.2 | 4.3 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.2 | 4.0 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.2 | 4.6 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.2 | 4.4 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.2 | 5.0 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.2 | 3.1 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.2 | 2.0 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.2 | 1.9 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.2 | 2.1 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 4.9 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.1 | 2.6 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.1 | 3.1 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.1 | 6.0 | REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | Genes involved in GRB2 events in ERBB2 signaling |
| 0.1 | 4.8 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 3.4 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 6.5 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.1 | 2.1 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 11.3 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 2.2 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 7.2 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 5.1 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.1 | 11.0 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 4.4 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 5.7 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 6.8 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 2.3 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 4.2 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.1 | 1.3 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 3.6 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 2.7 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.1 | 2.2 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 3.9 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 0.9 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.1 | 2.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 3.0 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.1 | 1.3 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 1.9 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.1 | 1.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.9 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.7 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.0 | 0.3 | REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.0 | 5.3 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.9 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.6 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.8 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 1.0 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 1.4 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 0.2 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 1.3 | REACTOME BIOLOGICAL OXIDATIONS | Genes involved in Biological oxidations |
| 0.0 | 1.3 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 0.8 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.3 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.0 | 0.4 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.7 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 1.5 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.6 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 2.3 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |