Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for GCAGCAU
Z-value: 0.65
Motif logo
miRNA associated with seed GCAGCAU
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_152017181 Show fit | 10.41 |
ENST00000498502.1
ENST00000324196.5 ENST00000545754.1 ENST00000357472.3 |
muscleblind-like splicing regulator 1 |
|
| chr4_+_174089904 Show fit | 10.34 |
ENST00000265000.4
|
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) |
|
| chr12_+_104359576 Show fit | 8.38 |
ENST00000392872.3
ENST00000436021.2 |
thymine-DNA glycosylase |
|
| chr12_-_31479045 Show fit | 8.30 |
ENST00000539409.1
ENST00000395766.1 |
family with sequence similarity 60, member A |
|
| chr5_-_98262240 Show fit | 7.90 |
ENST00000284049.3
|
chromodomain helicase DNA binding protein 1 |
|
| chrX_-_109561294 Show fit | 7.74 |
ENST00000372059.2
ENST00000262844.5 |
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
|
| chr12_-_102513843 Show fit | 7.39 |
ENST00000551744.2
ENST00000552283.1 |
nucleoporin 37kDa |
|
| chr5_+_65440032 Show fit | 7.09 |
ENST00000334121.6
|
splicing regulatory glutamine/lysine-rich protein 1 |
|
| chr1_-_11120057 Show fit | 6.86 |
ENST00000376957.2
|
spermidine synthase |
|
| chrX_-_20284958 Show fit | 6.55 |
ENST00000379565.3
|
ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GCAGCAU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.4 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.2 | 10.2 | GO:0016266 | O-glycan processing(GO:0016266) |
| 2.2 | 8.8 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 2.1 | 8.4 | GO:1902544 | oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.2 | 8.0 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.4 | 7.9 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.2 | 7.2 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.1 | 7.1 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 1.1 | 6.9 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 0.2 | 6.5 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.6 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.2 | 10.6 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.2 | 10.2 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 10.0 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 9.0 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
| 0.8 | 8.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.3 | 8.3 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.5 | 7.4 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 7.3 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 6.6 | GO:0005681 | spliceosomal complex(GO:0005681) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 10.4 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.7 | 10.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.7 | 9.6 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.2 | 9.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 2.8 | 8.4 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.2 | 7.9 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.7 | 7.7 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 7.5 | GO:0002039 | p53 binding(GO:0002039) |
| 0.2 | 7.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 2.3 | 6.9 | GO:0004766 | spermidine synthase activity(GO:0004766) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 14.4 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.1 | 13.6 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 7.6 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 4.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.2 | 4.5 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 4.2 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 4.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 3.5 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 3.5 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 2.9 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 12.0 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.2 | 10.2 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.2 | 10.0 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.5 | 8.4 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 8.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 6.6 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.1 | 5.9 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 5.8 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 5.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 5.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |