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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for GFI1

Z-value: 0.74

Motif logo

Transcription factors associated with GFI1

Gene Symbol Gene ID Gene Info
ENSG00000162676.7 growth factor independent 1 transcriptional repressor

Activity-expression correlation:

Activity profile of GFI1 motif

Sorted Z-values of GFI1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_26694979 11.66 ENST00000438614.1
vitronectin
chr17_+_1665345 11.48 ENST00000576406.1
ENST00000571149.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_-_26695013 10.84 ENST00000555059.2
Homeobox protein SEBOX
chr6_+_31982539 9.61 ENST00000435363.2
ENST00000425700.2
complement component 4B (Chido blood group)
chr6_+_31949801 9.60 ENST00000428956.2
ENST00000498271.1
complement component 4A (Rodgers blood group)
chr11_-_117748138 9.42 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr6_+_31795506 7.51 ENST00000375650.3
heat shock 70kDa protein 1B
chr17_+_1665253 7.43 ENST00000254722.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_-_22005062 7.21 ENST00000317492.5
spalt-like transcription factor 2
chr14_-_22005343 7.20 ENST00000327430.3
spalt-like transcription factor 2
chr2_-_89157161 6.35 ENST00000390237.2
immunoglobulin kappa constant
chr4_-_155533787 5.49 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr5_+_66254698 5.48 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
microtubule associated serine/threonine kinase family member 4
chr2_+_17721920 5.38 ENST00000295156.4
visinin-like 1
chr6_-_52859046 5.02 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr5_-_35230434 4.87 ENST00000504500.1
prolactin receptor
chr1_-_173793458 4.75 ENST00000356198.2
centromere protein L
chr15_+_84115868 4.67 ENST00000427482.2
SH3-domain GRB2-like 3
chr10_+_124221036 4.63 ENST00000368984.3
HtrA serine peptidase 1
chr8_-_27115931 4.60 ENST00000523048.1
stathmin-like 4
chr15_+_84116106 4.60 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr2_+_17721230 4.60 ENST00000457525.1
visinin-like 1
chr6_+_45296391 4.60 ENST00000371436.6
ENST00000576263.1
runt-related transcription factor 2
chr7_+_100136811 4.57 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr17_-_66951474 4.53 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr11_+_71791849 4.47 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
leucine rich transmembrane and O-methyltransferase domain containing
chr7_+_98246588 4.40 ENST00000265634.3
neuronal pentraxin II
chr1_-_153348067 4.34 ENST00000368737.3
S100 calcium binding protein A12
chr6_+_45296048 4.30 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
runt-related transcription factor 2
chr19_+_50353944 4.29 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
prostate tumor overexpressed 1
chr14_-_93214915 4.27 ENST00000553918.1
ENST00000555699.1
ENST00000553802.1
ENST00000554397.1
ENST00000554919.1
ENST00000554080.1
ENST00000553371.1
legumain
chr11_+_117049445 4.19 ENST00000324225.4
ENST00000532960.1
SID1 transmembrane family, member 2
chr19_+_47813110 4.18 ENST00000355085.3
complement component 5a receptor 1
chr19_-_49140609 4.15 ENST00000601104.1
D site of albumin promoter (albumin D-box) binding protein
chr19_+_55477711 4.06 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
NLR family, pyrin domain containing 2
chrX_+_133507327 4.04 ENST00000332070.3
ENST00000394292.1
ENST00000370799.1
ENST00000416404.2
PHD finger protein 6
chr14_-_93214988 4.02 ENST00000557434.1
ENST00000393218.2
ENST00000334869.4
legumain
chr6_-_46293378 4.01 ENST00000330430.6
regulator of calcineurin 2
chrX_+_37639302 4.01 ENST00000545017.1
ENST00000536160.1
cytochrome b-245, beta polypeptide
chr8_-_27115903 3.95 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr11_+_117049854 3.95 ENST00000278951.7
SID1 transmembrane family, member 2
chr11_+_71900703 3.90 ENST00000393681.2
folate receptor 1 (adult)
chr17_-_56606705 3.86 ENST00000317268.3
septin 4
chr5_+_36608422 3.77 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_+_71791693 3.77 ENST00000289488.2
ENST00000447974.1
leucine rich transmembrane and O-methyltransferase domain containing
chr17_-_56606664 3.76 ENST00000580844.1
septin 4
chr19_-_19302931 3.75 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr5_-_88179302 3.75 ENST00000504921.2
myocyte enhancer factor 2C
chr3_-_187388173 3.71 ENST00000287641.3
somatostatin
chr4_-_89744314 3.67 ENST00000508369.1
family with sequence similarity 13, member A
chr3_-_114343039 3.66 ENST00000481632.1
zinc finger and BTB domain containing 20
chr11_+_71900572 3.65 ENST00000312293.4
folate receptor 1 (adult)
chr17_-_56606639 3.64 ENST00000579371.1
septin 4
chr4_-_681114 3.61 ENST00000503156.1
major facilitator superfamily domain containing 7
chr1_-_173793246 3.61 ENST00000345664.6
ENST00000367710.3
centromere protein L
chr2_+_148602058 3.60 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
activin A receptor, type IIA
chr17_+_3539998 3.55 ENST00000452111.1
ENST00000574776.1
ENST00000441220.2
ENST00000414524.2
cystinosin, lysosomal cystine transporter
chr19_-_44123734 3.51 ENST00000598676.1
zinc finger protein 428
chr17_-_7017968 3.50 ENST00000355035.5
asialoglycoprotein receptor 2
chr13_-_67802549 3.42 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr19_+_41103063 3.39 ENST00000308370.7
latent transforming growth factor beta binding protein 4
chr17_-_7018128 3.38 ENST00000380952.2
ENST00000254850.7
asialoglycoprotein receptor 2
chr11_-_82746587 3.38 ENST00000528379.1
ENST00000534103.1
RAB30, member RAS oncogene family
chr2_-_152830479 3.36 ENST00000360283.6
calcium channel, voltage-dependent, beta 4 subunit
chr12_+_8276495 3.35 ENST00000546339.1
C-type lectin domain family 4, member A
chr4_-_89744365 3.33 ENST00000513837.1
ENST00000503556.1
family with sequence similarity 13, member A
chr6_+_31553978 3.31 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr19_-_49140692 3.31 ENST00000222122.5
D site of albumin promoter (albumin D-box) binding protein
chr8_-_119964434 3.30 ENST00000297350.4
tumor necrosis factor receptor superfamily, member 11b
chr6_+_41040678 3.28 ENST00000341376.6
ENST00000353205.5
nuclear transcription factor Y, alpha
chr19_+_55476620 3.27 ENST00000543010.1
ENST00000391721.4
ENST00000339757.7
NLR family, pyrin domain containing 2
chr14_-_23285069 3.27 ENST00000554758.1
ENST00000397528.4
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_-_152830441 3.26 ENST00000534999.1
ENST00000397327.2
calcium channel, voltage-dependent, beta 4 subunit
chr6_+_31554636 3.26 ENST00000433492.1
leukocyte specific transcript 1
chr22_-_32334403 3.24 ENST00000543051.1
chromosome 22 open reading frame 24
chr3_+_40518599 3.23 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
zinc finger protein 619
chr1_+_163039143 3.19 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
regulator of G-protein signaling 4
chr15_-_23932437 3.18 ENST00000331837.4
necdin, melanoma antigen (MAGE) family member
chr14_-_70263979 3.17 ENST00000216540.4
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr8_+_58890917 3.14 ENST00000522992.1
RP11-1112C15.1
chr1_-_67142710 3.12 ENST00000502413.2
Uncharacterized protein
chr1_-_120311517 3.11 ENST00000369406.3
ENST00000544913.2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr3_-_66024213 3.10 ENST00000483466.1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr2_+_66662690 3.08 ENST00000488550.1
Meis homeobox 1
chr1_-_230513367 3.08 ENST00000321327.2
ENST00000525115.1
piggyBac transposable element derived 5
chr2_+_189839046 3.07 ENST00000304636.3
ENST00000317840.5
collagen, type III, alpha 1
chr19_-_17488143 3.04 ENST00000599426.1
ENST00000252590.4
plasmalemma vesicle associated protein
chrX_-_14047996 3.02 ENST00000380523.4
ENST00000398355.3
gem (nuclear organelle) associated protein 8
chr9_+_71939488 3.01 ENST00000455972.1
family with sequence similarity 189, member A2
chr19_-_44124019 3.00 ENST00000300811.3
zinc finger protein 428
chr2_+_183943464 2.96 ENST00000354221.4
dual specificity phosphatase 19
chr14_-_23285011 2.91 ENST00000397532.3
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_+_31553901 2.89 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
leukocyte specific transcript 1
chr17_+_19281034 2.88 ENST00000308406.5
ENST00000299612.7
mitogen-activated protein kinase 7
chr2_+_79412357 2.87 ENST00000466387.1
catenin (cadherin-associated protein), alpha 2
chr17_+_68071458 2.87 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr18_-_53257027 2.84 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
transcription factor 4
chr8_+_133931648 2.83 ENST00000519178.1
ENST00000542445.1
thyroglobulin
chr17_+_4675175 2.81 ENST00000270560.3
transmembrane 4 L six family member 5
chr6_-_135271260 2.81 ENST00000265605.2
aldehyde dehydrogenase 8 family, member A1
chr2_+_66662510 2.81 ENST00000272369.9
ENST00000407092.2
Meis homeobox 1
chr12_+_81110684 2.79 ENST00000228644.3
myogenic factor 5
chrX_-_102319092 2.78 ENST00000372728.3
brain expressed, X-linked 1
chr11_-_65548265 2.76 ENST00000532090.2
adaptor-related protein complex 5, beta 1 subunit
chr1_+_164528866 2.74 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr1_+_173793777 2.73 ENST00000239457.5
aspartyl-tRNA synthetase 2, mitochondrial
chr17_+_76311791 2.73 ENST00000586321.1
AC061992.2
chr3_+_46412345 2.72 ENST00000292303.4
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr2_+_157292859 2.71 ENST00000438166.2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr6_-_135271219 2.71 ENST00000367847.2
ENST00000367845.2
aldehyde dehydrogenase 8 family, member A1
chrX_-_55020511 2.65 ENST00000375006.3
ENST00000374992.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr11_-_71791518 2.65 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
nuclear mitotic apparatus protein 1
chr12_+_113659234 2.64 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
two pore segment channel 1
chr3_+_186435137 2.64 ENST00000447445.1
kininogen 1
chr5_+_178368186 2.63 ENST00000320129.3
ENST00000519564.1
zinc finger protein 454
chr10_-_100995540 2.62 ENST00000370546.1
ENST00000404542.1
heparanase 2
chr10_-_100995603 2.60 ENST00000370552.3
ENST00000370549.1
heparanase 2
chr11_+_2323349 2.60 ENST00000381121.3
tetraspanin 32
chrX_+_48681768 2.60 ENST00000430858.1
histone deacetylase 6
chr1_+_196621002 2.58 ENST00000367429.4
ENST00000439155.2
complement factor H
chr10_-_82049424 2.57 ENST00000372213.3
methionine adenosyltransferase I, alpha
chr4_+_56814968 2.56 ENST00000422247.2
centrosomal protein 135kDa
chr2_+_1418154 2.55 ENST00000423320.1
ENST00000382198.1
thyroid peroxidase
chr4_+_84377115 2.54 ENST00000295491.4
ENST00000507019.1
mitochondrial ribosomal protein S18C
chr11_-_104034827 2.49 ENST00000393158.2
platelet derived growth factor D
chr2_+_26915584 2.49 ENST00000302909.3
potassium channel, subfamily K, member 3
chr9_-_79520989 2.46 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
prune homolog 2 (Drosophila)
chr21_-_36421535 2.46 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
runt-related transcription factor 1
chrX_+_84499081 2.42 ENST00000276123.3
zinc finger protein 711
chr7_-_140482926 2.38 ENST00000496384.2
v-raf murine sarcoma viral oncogene homolog B
chr17_-_56595196 2.38 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
myotubularin related protein 4
chr5_+_140588269 2.37 ENST00000541609.1
ENST00000239450.2
protocadherin beta 12
chr19_-_18391708 2.37 ENST00000600972.1
jun D proto-oncogene
chr17_-_62340581 2.36 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
testis expressed 2
chr4_-_89744457 2.36 ENST00000395002.2
family with sequence similarity 13, member A
chr15_+_92397051 2.36 ENST00000424469.2
solute carrier organic anion transporter family, member 3A1
chrX_+_138612889 2.35 ENST00000218099.2
ENST00000394090.2
coagulation factor IX
chr11_-_72432950 2.34 ENST00000426523.1
ENST00000429686.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr5_+_140729649 2.34 ENST00000523390.1
protocadherin gamma subfamily B, 1
chr13_+_31191920 2.33 ENST00000255304.4
ubiquitin specific peptidase like 1
chr17_+_68071389 2.33 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_-_114477962 2.32 ENST00000471418.1
zinc finger and BTB domain containing 20
chr2_-_9143786 2.32 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr11_-_4629388 2.31 ENST00000526337.1
ENST00000300747.5
tripartite motif containing 68
chr6_+_31554612 2.31 ENST00000211921.7
leukocyte specific transcript 1
chrX_+_84499038 2.30 ENST00000373165.3
zinc finger protein 711
chr14_-_106069247 2.30 ENST00000479229.1
RP11-731F5.1
chrY_+_16168097 2.29 ENST00000250823.4
variable charge, Y-linked 1B
chr20_-_23066953 2.28 ENST00000246006.4
CD93 molecule
chr3_+_186435065 2.28 ENST00000287611.2
ENST00000265023.4
kininogen 1
chr19_-_15529790 2.26 ENST00000596195.1
ENST00000595067.1
ENST00000595465.2
ENST00000397410.5
ENST00000600247.1
A kinase (PRKA) anchor protein 8-like
chr7_+_86273218 2.26 ENST00000361669.2
glutamate receptor, metabotropic 3
chrX_+_100353153 2.25 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
centromere protein I
chr6_+_6588316 2.24 ENST00000379953.2
lymphocyte antigen 86
chr6_+_31554456 2.24 ENST00000339530.4
leukocyte specific transcript 1
chr11_-_71791726 2.23 ENST00000393695.3
nuclear mitotic apparatus protein 1
chr20_-_3065362 2.22 ENST00000380293.3
arginine vasopressin
chr18_-_59854203 2.21 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
phosphatidylinositol glycan anchor biosynthesis, class N
chr1_+_176432298 2.21 ENST00000367661.3
ENST00000367662.3
pappalysin 2
chr7_-_27187393 2.20 ENST00000222728.3
homeobox A6
chr3_-_38835501 2.19 ENST00000449082.2
sodium channel, voltage-gated, type X, alpha subunit
chr1_+_156338993 2.19 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
Rh family, B glycoprotein (gene/pseudogene)
chr2_+_85360499 2.19 ENST00000282111.3
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr17_+_3539744 2.19 ENST00000046640.3
ENST00000381870.3
cystinosin, lysosomal cystine transporter
chr5_-_142000883 2.18 ENST00000359370.6
fibroblast growth factor 1 (acidic)
chr5_+_140261703 2.17 ENST00000409494.1
ENST00000289272.2
protocadherin alpha 13
chr3_-_114477787 2.17 ENST00000464560.1
zinc finger and BTB domain containing 20
chr12_+_56732658 2.15 ENST00000228534.4
interleukin 23, alpha subunit p19
chr11_+_61717279 2.14 ENST00000378043.4
bestrophin 1
chr18_-_53177984 2.14 ENST00000543082.1
transcription factor 4
chr4_-_144940477 2.12 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
glycophorin B (MNS blood group)
chr11_+_61717336 2.11 ENST00000378042.3
bestrophin 1
chr4_-_145061788 2.10 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
glycophorin A (MNS blood group)
glycophorin B (MNS blood group)
chrX_+_84498989 2.09 ENST00000395402.1
zinc finger protein 711
chr7_-_87104963 2.06 ENST00000359206.3
ENST00000358400.3
ENST00000265723.4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr17_-_8093471 2.05 ENST00000389017.4
chromosome 17 open reading frame 59
chr18_-_78005231 2.05 ENST00000470488.2
ENST00000353265.3
par-6 family cell polarity regulator gamma
chr9_+_42717234 2.04 ENST00000377590.1
forkhead box D4-like 2
chr2_+_233390863 2.04 ENST00000449596.1
ENST00000543200.1
cholinergic receptor, nicotinic, delta (muscle)
chr12_+_81101277 2.02 ENST00000228641.3
myogenic factor 6 (herculin)
chr16_+_31366455 2.02 ENST00000268296.4
integrin, alpha X (complement component 3 receptor 4 subunit)
chrX_+_12885183 2.00 ENST00000380659.3
toll-like receptor 7
chr5_+_147763539 1.99 ENST00000296701.6
ENST00000394370.3
F-box protein 38
chr14_+_103995546 1.99 ENST00000299202.4
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr5_+_147763498 1.98 ENST00000340253.5
F-box protein 38
chr16_+_67360712 1.95 ENST00000569499.2
ENST00000329956.6
ENST00000561948.1
leucine rich repeat containing 36
chr4_+_106631966 1.95 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr16_+_82090028 1.94 ENST00000568090.1
hydroxysteroid (17-beta) dehydrogenase 2
chr21_-_36421401 1.94 ENST00000486278.2
runt-related transcription factor 1
chr16_-_90038866 1.93 ENST00000314994.3
CENPB DNA-binding domains containing 1
chr9_-_35115836 1.91 ENST00000378566.1
ENST00000378554.2
ENST00000322813.5
family with sequence similarity 214, member B
chr11_+_6280927 1.91 ENST00000334619.2
cholecystokinin B receptor
chr7_-_115670792 1.91 ENST00000265440.7
ENST00000393485.1
transcription factor EC
chrX_-_48056199 1.90 ENST00000311798.1
ENST00000347757.1
synovial sarcoma, X breakpoint 5
chr19_+_55417530 1.89 ENST00000350790.5
ENST00000338835.5
ENST00000357397.5
natural cytotoxicity triggering receptor 1
chr7_-_120498357 1.88 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr19_-_16045619 1.88 ENST00000402119.4
cytochrome P450, family 4, subfamily F, polypeptide 11
chr12_+_110011571 1.86 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
mevalonate kinase
chr12_+_8276224 1.85 ENST00000229332.5
C-type lectin domain family 4, member A
chr19_-_15311713 1.84 ENST00000601011.1
ENST00000263388.2
notch 3

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 18.9 GO:0071279 cellular response to cobalt ion(GO:0071279)
2.8 8.3 GO:0006624 vacuolar protein processing(GO:0006624)
2.5 7.5 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
2.3 11.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
1.9 7.5 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
1.6 4.9 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
1.5 4.5 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.5 19.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.4 4.2 GO:0038178 complement component C5a signaling pathway(GO:0038178)
1.4 4.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
1.3 11.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.3 1.3 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
1.3 7.6 GO:0038161 prolactin signaling pathway(GO:0038161)
1.2 3.5 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
1.1 6.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
1.1 8.9 GO:0002051 osteoblast fate commitment(GO:0002051)
1.1 4.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
1.1 4.2 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
1.0 3.0 GO:0097254 renal tubular secretion(GO:0097254)
1.0 5.7 GO:0015811 L-cystine transport(GO:0015811)
0.9 3.7 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.9 4.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.9 3.7 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.9 3.6 GO:0042713 sperm ejaculation(GO:0042713)
0.9 4.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.9 9.6 GO:0033227 dsRNA transport(GO:0033227)
0.9 2.6 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.8 2.5 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.8 4.0 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.8 3.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.7 2.2 GO:0002125 maternal aggressive behavior(GO:0002125)
0.7 2.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.7 3.5 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.7 2.1 GO:0097327 response to antineoplastic agent(GO:0097327) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.7 2.0 GO:1902866 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.7 2.0 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.6 2.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 1.3 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.6 1.9 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.6 3.1 GO:0070997 neuron death(GO:0070997)
0.6 1.8 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.6 2.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.6 1.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.5 1.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 3.8 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5 1.6 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.5 1.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.5 5.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.5 2.9 GO:0033121 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.5 5.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.5 1.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.5 8.2 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.5 4.5 GO:0042908 xenobiotic transport(GO:0042908)
0.5 2.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.4 1.3 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.4 2.7 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.4 4.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.4 2.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.4 2.2 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.4 1.2 GO:0043132 NAD transport(GO:0043132)
0.4 2.0 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.4 0.8 GO:0061010 gall bladder development(GO:0061010)
0.4 2.7 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4 3.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 12.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.4 3.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.4 1.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 6.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.4 1.1 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.4 1.4 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.3 1.0 GO:1990502 dense core granule maturation(GO:1990502)
0.3 5.0 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.3 5.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.3 2.8 GO:0015705 iodide transport(GO:0015705)
0.3 0.9 GO:0034201 response to oleic acid(GO:0034201)
0.3 1.8 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.3 0.9 GO:0035963 cellular response to interleukin-13(GO:0035963)
0.3 2.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.3 2.3 GO:0016926 protein desumoylation(GO:0016926)
0.3 1.5 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.3 2.9 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.3 0.9 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.3 1.7 GO:0001714 endodermal cell fate specification(GO:0001714)
0.3 1.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.3 1.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.3 1.8 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.3 3.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.3 2.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.3 9.5 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.2 2.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.2 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.2 1.7 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684) cornea development in camera-type eye(GO:0061303)
0.2 0.7 GO:0002384 hepatic immune response(GO:0002384)
0.2 0.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2 4.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 8.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 1.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 6.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 2.9 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 0.4 GO:0009749 response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.2 6.5 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.2 5.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 0.6 GO:0048867 stem cell fate determination(GO:0048867)
0.2 2.1 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)
0.2 3.1 GO:0021670 lateral ventricle development(GO:0021670)
0.2 3.0 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.2 0.9 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 0.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 1.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 4.9 GO:0010107 potassium ion import(GO:0010107)
0.2 7.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 1.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 2.6 GO:0015732 prostaglandin transport(GO:0015732)
0.2 5.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 2.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 5.1 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.2 1.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.2 0.8 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 1.7 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.2 2.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.6 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 3.6 GO:0030252 growth hormone secretion(GO:0030252)
0.1 5.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 7.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 1.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 6.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 1.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.5 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 3.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.6 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 4.3 GO:0050832 defense response to fungus(GO:0050832)
0.1 2.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 6.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.7 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 2.5 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 2.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 3.2 GO:0003016 respiratory system process(GO:0003016)
0.1 8.9 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 2.3 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 6.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.8 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 2.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 13.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.7 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.7 GO:1901898 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 3.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.5 GO:0021764 amygdala development(GO:0021764)
0.1 5.1 GO:0006968 cellular defense response(GO:0006968)
0.1 1.7 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 0.8 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 5.9 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 2.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 0.5 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.1 1.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.1 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 3.5 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 1.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.4 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 1.6 GO:0006869 lipid transport(GO:0006869) lipid localization(GO:0010876)
0.1 1.1 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.1 2.9 GO:0097484 dendrite extension(GO:0097484)
0.1 1.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 1.3 GO:0072337 modified amino acid transport(GO:0072337)
0.1 0.6 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 1.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 2.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 1.2 GO:0050900 leukocyte migration(GO:0050900)
0.1 0.2 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 2.2 GO:0060349 bone morphogenesis(GO:0060349)
0.1 0.9 GO:0061053 somite development(GO:0061053)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.9 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.2 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 1.0 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 1.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 2.3 GO:0042116 macrophage activation(GO:0042116)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 1.0 GO:0030728 ovulation(GO:0030728)
0.0 3.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0072278 thyroid-stimulating hormone secretion(GO:0070460) metanephric comma-shaped body morphogenesis(GO:0072278) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.8 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 1.1 GO:0072431 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 2.5 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 1.5 GO:0070206 protein trimerization(GO:0070206)
0.0 1.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 2.2 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.6 GO:0006833 water transport(GO:0006833)
0.0 0.7 GO:0033622 integrin activation(GO:0033622)
0.0 0.5 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 2.2 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.9 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 1.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.7 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.0 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 2.4 GO:0051591 response to cAMP(GO:0051591)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 4.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 2.1 GO:0046718 viral entry into host cell(GO:0046718)
0.0 2.6 GO:0007417 central nervous system development(GO:0007417)
0.0 0.6 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 2.2 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 1.7 GO:0006665 sphingolipid metabolic process(GO:0006665)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.7 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.6 4.9 GO:0061673 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
1.6 18.9 GO:0043203 axon hillock(GO:0043203)
1.2 8.3 GO:0036021 endolysosome lumen(GO:0036021)
1.0 3.1 GO:0005879 axonemal microtubule(GO:0005879)
0.9 3.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.8 11.3 GO:0097227 sperm annulus(GO:0097227)
0.7 3.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.7 2.0 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.6 3.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5 7.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 5.5 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.7 GO:1990246 uniplex complex(GO:1990246)
0.4 1.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.4 3.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.4 1.8 GO:0000801 central element(GO:0000801)
0.4 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.3 10.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 5.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.3 1.2 GO:0097224 sperm connecting piece(GO:0097224)
0.3 3.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 1.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 2.4 GO:0035976 AP1 complex(GO:0035976)
0.3 2.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 0.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 3.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 4.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 2.0 GO:0032009 early phagosome(GO:0032009)
0.2 11.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.2 9.7 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 7.8 GO:0031904 endosome lumen(GO:0031904)
0.1 1.1 GO:0005610 laminin-5 complex(GO:0005610)
0.1 3.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 2.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 6.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 6.8 GO:0016235 aggresome(GO:0016235)
0.1 2.1 GO:0005922 connexon complex(GO:0005922)
0.1 0.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 2.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.0 GO:0005901 caveola(GO:0005901)
0.1 28.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 4.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 2.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 3.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 1.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 13.1 GO:0030426 growth cone(GO:0030426)
0.1 9.9 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.1 GO:0000145 exocyst(GO:0000145)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 26.4 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.2 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 4.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 5.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 4.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 3.2 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 16.4 GO:0030424 axon(GO:0030424)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 2.7 GO:0005811 lipid particle(GO:0005811)
0.0 2.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 13.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.7 GO:0005795 Golgi stack(GO:0005795)
0.0 3.8 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 2.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 3.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 5.9 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 39.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 12.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.2 GO:0044297 cell body(GO:0044297)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.2 GO:0042383 sarcolemma(GO:0042383)
0.0 0.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.5 GO:0098794 postsynapse(GO:0098794)
0.0 4.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.6 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 1.5 GO:0098793 presynapse(GO:0098793)
0.0 0.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0032090 Pyrin domain binding(GO:0032090)
1.9 7.5 GO:0061714 folic acid receptor activity(GO:0061714)
1.6 9.6 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.5 7.6 GO:0004925 prolactin receptor activity(GO:0004925)
1.5 11.9 GO:0001849 complement component C1q binding(GO:0001849)
1.4 4.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
1.3 5.2 GO:0030305 heparanase activity(GO:0030305)
1.2 3.5 GO:0004951 cholecystokinin receptor activity(GO:0004951)
1.2 8.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
1.2 3.5 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
1.0 5.7 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.9 4.5 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.9 3.5 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.9 2.6 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.9 5.3 GO:0098821 BMP receptor activity(GO:0098821)
0.9 6.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.8 6.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.8 11.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.8 2.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.7 2.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.7 7.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.7 4.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7 2.0 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.6 2.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.6 3.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.6 6.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.5 1.6 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.5 3.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 2.7 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.5 1.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.5 1.9 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.5 5.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.5 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 2.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.4 2.2 GO:0031893 vasopressin receptor binding(GO:0031893)
0.4 1.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) azole transmembrane transporter activity(GO:1901474)
0.4 2.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.4 7.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 5.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.4 5.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 1.5 GO:0015265 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.4 4.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.4 9.6 GO:0001848 complement binding(GO:0001848)
0.4 1.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 1.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.3 1.0 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.3 1.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.3 3.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 2.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.3 2.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.3 5.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 3.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 5.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 0.7 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.2 1.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241)
0.2 0.7 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.2 2.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.2 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 3.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 3.7 GO:0003680 AT DNA binding(GO:0003680)
0.2 4.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.9 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 2.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 2.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 4.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 0.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 0.6 GO:0017129 triglyceride binding(GO:0017129)
0.2 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.2 2.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 2.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 3.2 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.2 6.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 18.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 7.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.0 GO:0035197 siRNA binding(GO:0035197)
0.2 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.2 3.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.2 7.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 2.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 3.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 1.4 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 0.6 GO:0035473 lipase binding(GO:0035473)
0.1 4.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 2.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 2.9 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.4 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 1.2 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 2.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 6.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.7 GO:0070888 E-box binding(GO:0070888)
0.1 2.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 2.2 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 1.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 3.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 1.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 3.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 3.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.9 GO:0005112 Notch binding(GO:0005112)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.3 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.1 1.0 GO:0005372 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.1 0.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.8 GO:0031013 troponin I binding(GO:0031013)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.2 GO:0016866 intramolecular transferase activity(GO:0016866)
0.1 2.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 3.1 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 35.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 1.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 2.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.6 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.3 GO:0019894 kinesin binding(GO:0019894)
0.0 3.3 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 8.4 GO:0015631 tubulin binding(GO:0015631)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 7.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 13.4 GO:0005509 calcium ion binding(GO:0005509)
0.0 5.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 4.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.7 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 13.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 8.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 9.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 9.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 31.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.2 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.2 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 5.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.1 3.4 PID FGF PATHWAY FGF signaling pathway
0.1 1.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.2 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 3.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 4.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.5 2.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.5 9.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.4 5.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 7.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.4 2.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 7.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.3 3.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 9.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 2.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 13.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 4.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 3.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 8.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 4.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 5.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 2.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 1.8