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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for GGCAAGA
Z-value: 0.48
Motif logo
miRNA associated with seed GGCAAGA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-31-5p
|
MIMAT0000089 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_1532106 Show fit | 2.40 |
ENST00000301335.5
ENST00000382147.4 |
solute carrier family 43 (amino acid system L transporter), member 2 |
|
| chr12_-_42538657 Show fit | 2.35 |
ENST00000398675.3
|
glucoside xylosyltransferase 1 |
|
| chr16_+_58283814 Show fit | 2.22 |
ENST00000443128.2
ENST00000219299.4 |
coiled-coil domain containing 113 |
|
| chr17_-_27278304 Show fit | 2.03 |
ENST00000577226.1
|
PHD finger protein 12 |
|
| chr15_+_31619013 Show fit | 1.86 |
ENST00000307145.3
|
Kruppel-like factor 13 |
|
| chr16_+_30710462 Show fit | 1.83 |
ENST00000262518.4
ENST00000395059.2 ENST00000344771.4 |
Snf2-related CREBBP activator protein |
|
| chr2_-_218808771 Show fit | 1.81 |
ENST00000449814.1
ENST00000171887.4 |
tensin 1 |
|
| chr3_-_114790179 Show fit | 1.75 |
ENST00000462705.1
|
zinc finger and BTB domain containing 20 |
|
| chr12_-_49110613 Show fit | 1.71 |
ENST00000261900.3
|
cyclin T1 |
|
| chr2_-_9143786 Show fit | 1.65 |
ENST00000462696.1
ENST00000305997.3 |
membrane bound O-acyltransferase domain containing 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GGCAAGA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 2.8 | GO:1902475 | L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.2 | 1.9 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.0 | 1.9 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.4 | 1.8 | GO:0048319 | axial mesoderm morphogenesis(GO:0048319) |
| 0.0 | 1.8 | GO:0010761 | fibroblast migration(GO:0010761) |
| 0.1 | 1.7 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.0 | 1.5 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 1.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.1 | 1.4 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.2 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 1.9 | GO:0043204 | perikaryon(GO:0043204) |
| 0.2 | 1.7 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.1 | 1.5 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 1.5 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 1.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 1.4 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 1.3 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 1.3 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 1.2 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.4 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.5 | 2.3 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.1 | 2.0 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 1.8 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 1.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.2 | 1.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 1.7 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.0 | 1.7 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 1.7 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 1.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.2 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 1.7 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 1.7 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 1.6 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 1.2 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 1.2 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 1.0 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.9 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.8 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.0 | 0.8 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.4 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 2.1 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.1 | 1.7 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.0 | 1.7 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 1.6 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 1.6 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 1.5 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 1.4 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 1.4 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 1.3 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |