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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for GGCAGUG

Z-value: 0.97

Motif logo

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miRNA associated with seed GGCAGUG

NamemiRBASE accession
hsa-miR-34a-5p
MIMAT0000255
hsa-miR-34c-5p
MIMAT0000686
hsa-miR-449a
MIMAT0001541
hsa-miR-449b-5p
MIMAT0003327

Activity profile of GGCAGUG motif

Sorted Z-values of GGCAGUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_10199468 29.59 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chrX_+_64708615 27.91 ENST00000338957.4
ENST00000423889.3
ZC3H12B
zinc finger CCCH-type containing 12B
chr12_+_79258547 25.87 ENST00000457153.2
SYT1
synaptotagmin I
chr10_+_105036909 22.72 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr17_-_8066250 18.46 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
VAMP2
RP11-599B13.6
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr2_+_203499901 17.65 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr9_-_104249319 17.02 ENST00000374847.1
TMEM246
transmembrane protein 246
chr8_+_11141925 16.88 ENST00000221086.3
MTMR9
myotubularin related protein 9
chr16_+_56225248 15.66 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr17_+_43971643 15.42 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
MAPT
microtubule-associated protein tau
chr5_-_11904152 14.77 ENST00000304623.8
ENST00000458100.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr20_+_37434329 14.76 ENST00000299824.1
ENST00000373331.2
PPP1R16B
protein phosphatase 1, regulatory subunit 16B
chr1_+_160085501 14.56 ENST00000361216.3
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr9_-_101471479 13.92 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr19_+_18794470 12.88 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr3_-_18466787 12.00 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr1_-_41131326 11.97 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr17_+_40834580 11.82 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr10_-_62149433 11.24 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr19_-_46296011 11.13 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr6_-_6007200 11.05 ENST00000244766.2
NRN1
neuritin 1
chr14_-_77843390 10.81 ENST00000216468.7
TMED8
transmembrane emp24 protein transport domain containing 8
chr6_+_31795506 10.80 ENST00000375650.3
HSPA1B
heat shock 70kDa protein 1B
chr15_+_43803143 10.60 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chr8_+_42752053 10.01 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr2_-_201936302 9.57 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr1_+_28052456 9.56 ENST00000373954.6
ENST00000419687.2
FAM76A
family with sequence similarity 76, member A
chr9_-_86571628 9.54 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr9_+_126773880 9.35 ENST00000373615.4
LHX2
LIM homeobox 2
chr2_+_239335449 9.08 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr7_+_138916231 9.03 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr4_+_47033345 9.03 ENST00000295454.3
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr11_-_118047376 8.96 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr4_+_113970772 8.91 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr3_-_128879875 8.50 ENST00000418265.1
ENST00000393292.3
ENST00000273541.8
ISY1-RAB43
ISY1
ISY1-RAB43 readthrough
ISY1 splicing factor homolog (S. cerevisiae)
chr8_-_18871159 8.47 ENST00000327040.8
ENST00000440756.2
PSD3
pleckstrin and Sec7 domain containing 3
chr2_+_26915584 8.43 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr11_-_64410787 8.21 ENST00000301894.2
NRXN2
neurexin 2
chr7_+_87563458 8.20 ENST00000398204.4
ADAM22
ADAM metallopeptidase domain 22
chr1_+_84543734 8.07 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_134281812 7.92 ENST00000392580.1
ENST00000312527.4
B3GAT1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr17_-_61777459 7.87 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr7_-_44924939 7.77 ENST00000395699.2
PURB
purine-rich element binding protein B
chr12_+_107168342 7.76 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr11_-_62369291 7.59 ENST00000278823.2
MTA2
metastasis associated 1 family, member 2
chr7_-_103629963 7.53 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr1_+_205012293 7.41 ENST00000331830.4
CNTN2
contactin 2 (axonal)
chr8_-_96281419 7.38 ENST00000286688.5
C8orf37
chromosome 8 open reading frame 37
chr1_-_21978312 7.35 ENST00000359708.4
ENST00000290101.4
RAP1GAP
RAP1 GTPase activating protein
chr1_+_162039558 7.33 ENST00000530878.1
ENST00000361897.5
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr11_-_46722117 7.09 ENST00000311956.4
ARHGAP1
Rho GTPase activating protein 1
chr9_+_34958254 7.09 ENST00000242315.3
KIAA1045
KIAA1045
chr14_+_24583836 7.00 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11
DDB1 and CUL4 associated factor 11
chr9_-_138799070 6.74 ENST00000389532.4
ENST00000409386.3
CAMSAP1
calmodulin regulated spectrin-associated protein 1
chr17_-_71640227 6.68 ENST00000388726.3
ENST00000392650.3
SDK2
sidekick cell adhesion molecule 2
chr17_-_41977964 6.67 ENST00000377184.3
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chrX_+_23352133 6.61 ENST00000379361.4
PTCHD1
patched domain containing 1
chr13_-_27334879 6.61 ENST00000405846.3
GPR12
G protein-coupled receptor 12
chr3_-_114790179 6.60 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr17_-_62207485 6.59 ENST00000433197.3
ERN1
endoplasmic reticulum to nucleus signaling 1
chr3_+_138066539 6.45 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chrX_-_18372792 6.45 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr11_+_92085262 6.38 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr2_+_61404624 6.22 ENST00000394457.3
AHSA2
AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
chr18_-_65184217 6.16 ENST00000310045.7
DSEL
dermatan sulfate epimerase-like
chr2_+_16080659 6.09 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr5_+_172483347 5.99 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr11_+_107461948 5.99 ENST00000265840.7
ENST00000443271.2
ELMOD1
ELMO/CED-12 domain containing 1
chr17_+_29718642 5.97 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr9_-_135996537 5.77 ENST00000372050.3
ENST00000372047.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr9_-_122131696 5.74 ENST00000373964.2
ENST00000265922.3
BRINP1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr17_+_2240775 5.71 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chr7_-_139876812 5.65 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr5_-_132299313 5.58 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr12_+_74931551 5.53 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr17_-_1083078 5.45 ENST00000574266.1
ENST00000302538.5
ABR
active BCR-related
chr12_-_58135903 5.33 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr11_-_22851367 5.32 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chr11_+_64794875 5.28 ENST00000377244.3
ENST00000534637.1
ENST00000524831.1
SNX15
sorting nexin 15
chr1_-_151688528 5.27 ENST00000290585.4
CELF3
CUGBP, Elav-like family member 3
chr3_+_39851094 5.27 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr14_+_29234870 5.27 ENST00000382535.3
FOXG1
forkhead box G1
chr14_-_75389975 5.25 ENST00000555647.1
ENST00000557413.1
RPS6KL1
ribosomal protein S6 kinase-like 1
chr19_-_6279932 5.21 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr19_-_2783363 5.18 ENST00000221566.2
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr16_+_30077055 5.06 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_66878814 4.98 ENST00000394069.3
CA7
carbonic anhydrase VII
chr14_-_75593708 4.97 ENST00000557673.1
ENST00000238616.5
NEK9
NIMA-related kinase 9
chr12_+_27396901 4.97 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr9_-_3525968 4.96 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr5_+_149109825 4.91 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr22_-_38902325 4.91 ENST00000396821.3
ENST00000381633.3
DDX17
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr6_-_110500905 4.85 ENST00000392587.2
WASF1
WAS protein family, member 1
chr14_-_99737565 4.70 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr9_+_102668915 4.66 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr1_-_154474589 4.63 ENST00000304760.2
SHE
Src homology 2 domain containing E
chr9_-_139440314 4.62 ENST00000277541.6
NOTCH1
notch 1
chr11_-_119599794 4.59 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr2_-_157189180 4.58 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr1_+_66797687 4.57 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr22_+_29469012 4.56 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr14_+_23299088 4.56 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr17_-_37382105 4.55 ENST00000333461.5
STAC2
SH3 and cysteine rich domain 2
chr17_-_31620006 4.48 ENST00000225823.2
ASIC2
acid-sensing (proton-gated) ion channel 2
chr3_+_38495333 4.46 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr17_-_1420182 4.43 ENST00000421807.2
INPP5K
inositol polyphosphate-5-phosphatase K
chr9_+_103204553 4.38 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_+_96463840 4.36 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr7_-_71801980 4.33 ENST00000329008.5
CALN1
calneuron 1
chr2_+_48541776 4.29 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr10_+_95517566 4.29 ENST00000542308.1
LGI1
leucine-rich, glioma inactivated 1
chr19_+_54371114 4.29 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM
myeloid-associated differentiation marker
chr3_+_50712672 4.25 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr1_+_160175117 4.17 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr20_+_42875887 4.12 ENST00000342560.5
GDAP1L1
ganglioside induced differentiation associated protein 1-like 1
chr12_-_93323013 4.06 ENST00000322349.8
EEA1
early endosome antigen 1
chr17_+_42836329 4.03 ENST00000200557.6
ADAM11
ADAM metallopeptidase domain 11
chr12_-_49504655 3.95 ENST00000551782.1
ENST00000267102.8
LMBR1L
limb development membrane protein 1-like
chr5_+_175223313 3.90 ENST00000359546.4
CPLX2
complexin 2
chr11_-_2906979 3.89 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr2_+_24272543 3.88 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr8_-_133493200 3.80 ENST00000388996.4
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr19_-_14316980 3.80 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr5_+_176560742 3.71 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr8_-_82024290 3.68 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr3_-_50540854 3.56 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
CACNA2D2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr11_+_66025167 3.54 ENST00000394067.2
ENST00000316924.5
ENST00000421552.1
ENST00000394078.1
KLC2
kinesin light chain 2
chr11_-_9025541 3.46 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr4_+_94750014 3.37 ENST00000306011.3
ATOH1
atonal homolog 1 (Drosophila)
chr17_+_46125707 3.36 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1
nuclear factor, erythroid 2-like 1
chr5_-_175964366 3.34 ENST00000274811.4
RNF44
ring finger protein 44
chr9_-_89562104 3.32 ENST00000298743.7
GAS1
growth arrest-specific 1
chr2_-_166930131 3.28 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr7_+_142985308 3.28 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr17_+_33448593 3.27 ENST00000158009.5
FNDC8
fibronectin type III domain containing 8
chr13_+_42622781 3.24 ENST00000337343.4
ENST00000261491.5
ENST00000379274.2
DGKH
diacylglycerol kinase, eta
chr2_+_45168875 3.23 ENST00000260653.3
SIX3
SIX homeobox 3
chr9_+_103235365 3.19 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr5_+_49961727 3.17 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
PARP8
poly (ADP-ribose) polymerase family, member 8
chr6_+_136172820 3.13 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr3_-_53381539 3.04 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
DCP1A
decapping mRNA 1A
chr17_+_12692774 3.01 ENST00000379672.5
ENST00000340825.3
ARHGAP44
Rho GTPase activating protein 44
chr20_+_49348081 2.99 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr22_-_29784519 2.93 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr11_+_31391381 2.90 ENST00000465995.1
ENST00000536040.1
DNAJC24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr4_+_124320665 2.88 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_+_105471969 2.87 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr5_-_150948414 2.86 ENST00000261800.5
FAT2
FAT atypical cadherin 2
chr3_+_113251143 2.84 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr4_+_144257915 2.79 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr1_+_3607228 2.73 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73
tumor protein p73
chr4_-_109089573 2.72 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr6_-_30585009 2.70 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr15_+_71389281 2.70 ENST00000355327.3
THSD4
thrombospondin, type I, domain containing 4
chr22_+_40297079 2.67 ENST00000344138.4
ENST00000543252.1
GRAP2
GRB2-related adaptor protein 2
chr5_-_149492904 2.63 ENST00000286301.3
ENST00000511344.1
CSF1R
colony stimulating factor 1 receptor
chr7_+_2443202 2.53 ENST00000258711.6
CHST12
carbohydrate (chondroitin 4) sulfotransferase 12
chr4_+_81951957 2.50 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chr17_-_27224621 2.49 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
FLOT2
flotillin 2
chr5_+_54455946 2.49 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr18_+_55018044 2.48 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr9_+_129677039 2.47 ENST00000259351.5
ENST00000424082.2
ENST00000394022.3
ENST00000394011.3
ENST00000319107.4
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr2_+_242577027 2.47 ENST00000402096.1
ENST00000404914.3
ATG4B
autophagy related 4B, cysteine peptidase
chr11_+_46299199 2.46 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr16_+_68298405 2.45 ENST00000219343.6
ENST00000566834.1
ENST00000566454.1
SLC7A6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr7_+_20370746 2.43 ENST00000222573.4
ITGB8
integrin, beta 8
chr10_+_126490354 2.43 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr20_+_39765581 2.41 ENST00000244007.3
PLCG1
phospholipase C, gamma 1
chr10_+_134000404 2.41 ENST00000338492.4
ENST00000368629.1
DPYSL4
dihydropyrimidinase-like 4
chr3_+_11034403 2.41 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr1_+_151171012 2.39 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr15_+_79724858 2.33 ENST00000305428.3
KIAA1024
KIAA1024
chr18_+_55102917 2.32 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr2_-_239197201 2.31 ENST00000254658.3
PER2
period circadian clock 2
chr2_-_70995307 2.24 ENST00000264436.4
ENST00000355733.3
ENST00000447731.2
ENST00000430656.1
ENST00000413157.2
ADD2
adducin 2 (beta)
chr11_+_64126614 2.21 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr16_-_17564738 2.21 ENST00000261381.6
XYLT1
xylosyltransferase I
chr8_+_28174649 2.21 ENST00000301908.3
PNOC
prepronociceptin
chr12_+_112563335 2.19 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr5_-_138210977 2.18 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr11_+_117049445 2.18 ENST00000324225.4
ENST00000532960.1
SIDT2
SID1 transmembrane family, member 2
chr9_+_131549483 2.16 ENST00000372648.5
ENST00000539497.1
TBC1D13
TBC1 domain family, member 13
chr7_-_73133959 2.09 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A
syntaxin 1A (brain)
chrX_+_118108571 2.09 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr18_-_57027194 1.96 ENST00000251047.5
LMAN1
lectin, mannose-binding, 1
chr2_-_74570520 1.94 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
SLC4A5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr21_-_34100244 1.92 ENST00000382491.3
ENST00000357345.3
ENST00000429236.1
SYNJ1
synaptojanin 1
chr7_+_128864848 1.92 ENST00000325006.3
ENST00000446544.2
AHCYL2
adenosylhomocysteinase-like 2
chr7_-_143059845 1.91 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr11_+_35684288 1.87 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr5_+_110559784 1.87 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr9_-_131534160 1.86 ENST00000291900.2
ZER1
zyg-11 related, cell cycle regulator
chr8_-_42698433 1.82 ENST00000345117.2
ENST00000254250.3
THAP1
THAP domain containing, apoptosis associated protein 1
chr12_+_52306113 1.80 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1
activin A receptor type II-like 1
chr12_+_20522179 1.75 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr11_+_65405556 1.75 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
SIPA1
signal-induced proliferation-associated 1
chr17_+_61086917 1.69 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr8_+_9413410 1.69 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr10_-_30348439 1.66 ENST00000375377.1
KIAA1462
KIAA1462
chr8_-_60031762 1.64 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box

Network of associatons between targets according to the STRING database.

First level regulatory network of GGCAGUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
5.8 29.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
4.9 14.8 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
4.3 12.9 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
3.5 10.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
3.4 16.9 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
3.1 15.4 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
3.0 8.9 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
2.8 11.2 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.7 10.8 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.6 18.5 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
2.5 10.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
2.5 7.4 GO:0060168 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
2.4 7.3 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
2.4 7.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
2.3 22.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
2.2 9.0 GO:0046684 response to pyrethroid(GO:0046684)
2.1 8.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
2.0 6.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.9 7.5 GO:0097477 NMDA glutamate receptor clustering(GO:0097114) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.8 7.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.8 5.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
1.7 19.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.7 5.0 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
1.6 8.1 GO:0097338 response to clozapine(GO:0097338)
1.5 4.6 GO:0003241 atrioventricular node development(GO:0003162) cardiac right atrium morphogenesis(GO:0003213) growth involved in heart morphogenesis(GO:0003241) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
1.5 4.6 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.2 4.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
1.2 14.0 GO:0021978 telencephalon regionalization(GO:0021978)
1.1 4.4 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
1.1 6.6 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
1.1 4.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
1.0 8.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.0 4.1 GO:0016240 autophagosome docking(GO:0016240)
1.0 5.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.9 3.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.8 2.5 GO:0051697 protein delipidation(GO:0051697)
0.8 2.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.8 8.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.7 11.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.7 2.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.7 3.4 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.6 4.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.6 4.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.6 2.4 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.6 4.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.6 10.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.6 2.9 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.6 2.9 GO:0072069 thick ascending limb development(GO:0072023) DCT cell differentiation(GO:0072069) metanephric thick ascending limb development(GO:0072233) metanephric DCT cell differentiation(GO:0072240)
0.6 1.7 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.6 3.9 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.5 4.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.5 2.7 GO:0071895 odontoblast differentiation(GO:0071895)
0.5 6.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.5 3.7 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.5 1.9 GO:1904978 regulation of endosome organization(GO:1904978)
0.5 20.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.5 5.0 GO:0033227 dsRNA transport(GO:0033227)
0.4 0.9 GO:1903410 nitric oxide production involved in inflammatory response(GO:0002537) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.4 2.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.4 1.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.4 2.6 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.4 1.7 GO:0042631 cellular response to water deprivation(GO:0042631)
0.4 3.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.4 3.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.4 8.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 6.3 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.4 1.3 GO:0014042 posterior midgut development(GO:0007497) positive regulation of neuron maturation(GO:0014042)
0.4 5.8 GO:0021794 thalamus development(GO:0021794)
0.4 2.5 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.4 1.2 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.4 4.5 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.4 19.9 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.4 1.9 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.4 4.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 6.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.4 4.4 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.4 2.9 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.4 2.9 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.4 5.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.3 8.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 12.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 2.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 2.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.3 1.8 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)
0.3 3.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.3 5.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 8.2 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3 5.3 GO:0030575 nuclear body organization(GO:0030575)
0.3 1.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 1.4 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.3 2.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.3 1.9 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.3 5.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.3 6.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 1.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 14.8 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 2.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 3.8 GO:0060081 membrane hyperpolarization(GO:0060081)
0.2 0.9 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 2.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.2 3.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 1.4 GO:1901727 protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.2 0.8 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.2 0.6 GO:0060061 Spemann organizer formation(GO:0060061)
0.2 1.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.2 6.7 GO:0046710 GDP metabolic process(GO:0046710)
0.2 1.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 2.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.2 1.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 11.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 1.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.2 1.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 4.1 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 9.5 GO:0006400 tRNA modification(GO:0006400)
0.1 3.0 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.1 2.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 4.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.6 GO:0007379 segment specification(GO:0007379) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 3.3 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.1 4.9 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 0.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.7 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 20.3 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.1 1.2 GO:1901652 response to peptide(GO:1901652)
0.1 1.0 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 3.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 3.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.3 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 7.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 2.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 2.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 6.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 2.4 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.1 4.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 5.0 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.1 4.3 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 6.9 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.1 0.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.1 2.5 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 1.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 6.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 2.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 7.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.7 GO:0035640 exploration behavior(GO:0035640)
0.1 1.8 GO:0001935 endothelial cell proliferation(GO:0001935)
0.1 8.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 6.4 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 6.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 3.4 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 4.3 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 2.2 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 4.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.5 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 2.7 GO:0031295 T cell costimulation(GO:0031295)
0.0 3.7 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 2.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 6.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 1.9 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 1.7 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.7 GO:0034504 protein import into nucleus(GO:0006606) protein import(GO:0017038) protein localization to nucleus(GO:0034504) protein targeting to nucleus(GO:0044744) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
0.0 4.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.0 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.0 1.2 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 1.1 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.3 GO:1990748 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.8 GO:0001578 microtubule bundle formation(GO:0001578)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.5 50.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
5.2 25.9 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
4.6 13.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
3.1 15.4 GO:0045298 tubulin complex(GO:0045298)
2.8 8.5 GO:0071020 post-spliceosomal complex(GO:0071020)
2.5 10.0 GO:0070695 FHF complex(GO:0070695)
1.6 6.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.5 22.7 GO:0005883 neurofilament(GO:0005883)
1.5 7.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.2 7.1 GO:0097443 sorting endosome(GO:0097443)
1.2 3.5 GO:0016938 kinesin I complex(GO:0016938)
1.1 10.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.1 18.3 GO:0043194 axon initial segment(GO:0043194)
1.0 11.0 GO:0033010 paranodal junction(GO:0033010)
0.9 4.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.8 4.1 GO:0044308 axonal spine(GO:0044308)
0.8 2.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.8 15.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.7 7.4 GO:0033268 node of Ranvier(GO:0033268)
0.6 9.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.6 3.9 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.5 7.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 1.5 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.5 2.0 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.4 2.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.4 8.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 6.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 4.8 GO:0031209 SCAR complex(GO:0031209)
0.3 5.3 GO:0031045 dense core granule(GO:0031045)
0.3 12.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.3 16.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 7.4 GO:0097546 ciliary base(GO:0097546)
0.3 1.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.3 2.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.3 14.0 GO:0031430 M band(GO:0031430)
0.3 12.0 GO:0048786 presynaptic active zone(GO:0048786)
0.3 8.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 2.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 1.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 2.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 10.8 GO:0016235 aggresome(GO:0016235)
0.2 5.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.7 GO:0030314 junctional membrane complex(GO:0030314)
0.2 6.1 GO:1902710 GABA receptor complex(GO:1902710)
0.2 4.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 4.9 GO:0016592 mediator complex(GO:0016592)
0.1 4.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 6.7 GO:0005874 microtubule(GO:0005874)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 6.4 GO:0031519 PcG protein complex(GO:0031519)
0.1 14.8 GO:0043204 perikaryon(GO:0043204)
0.1 1.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 3.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 6.7 GO:0034704 calcium channel complex(GO:0034704)
0.1 2.5 GO:0002080 acrosomal membrane(GO:0002080)
0.1 12.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.7 GO:0005911 cell-cell junction(GO:0005911)
0.1 5.8 GO:0005903 brush border(GO:0005903)
0.1 4.9 GO:0030118 clathrin coat(GO:0030118)
0.1 13.2 GO:0005875 microtubule associated complex(GO:0005875)
0.1 3.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 33.1 GO:0030425 dendrite(GO:0030425)
0.1 2.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 8.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 5.5 GO:0043005 neuron projection(GO:0043005)
0.1 1.2 GO:0030027 lamellipodium(GO:0030027)
0.1 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 5.7 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 7.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 4.0 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 2.6 GO:0005856 cytoskeleton(GO:0005856)
0.0 5.2 GO:0005840 ribosome(GO:0005840)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 3.9 GO:0005938 cell cortex(GO:0005938)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 11.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 25.9 GO:0030348 syntaxin-3 binding(GO:0030348)
4.6 13.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
3.9 15.4 GO:0099609 microtubule lateral binding(GO:0099609)
2.6 7.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
2.5 7.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
2.1 6.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
2.0 52.0 GO:0017075 syntaxin-1 binding(GO:0017075)
1.8 9.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.7 5.2 GO:1904288 BAT3 complex binding(GO:1904288)
1.4 18.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
1.4 15.7 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.2 3.7 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.0 14.6 GO:1990239 steroid hormone binding(GO:1990239)
1.0 10.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
1.0 2.9 GO:0071837 HMG box domain binding(GO:0071837)
0.9 4.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.9 6.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.9 12.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.8 8.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.8 5.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.8 2.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.8 2.4 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.8 3.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.7 4.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.7 2.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.7 2.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.7 4.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.7 9.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.7 5.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.6 2.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.6 1.8 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.6 29.1 GO:0030507 spectrin binding(GO:0030507)
0.5 4.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.5 8.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.5 8.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 6.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.5 2.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.5 5.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 2.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4 10.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.4 2.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 7.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 8.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 1.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 2.2 GO:0001515 opioid peptide activity(GO:0001515)
0.3 10.6 GO:0001671 ATPase activator activity(GO:0001671)
0.3 1.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 0.9 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.3 5.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 32.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 9.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.3 4.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 6.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.3 7.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.4 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.2 12.7 GO:0043621 protein self-association(GO:0043621)
0.2 3.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 5.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 6.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 7.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 2.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 2.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 2.7 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 0.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 2.5 GO:0070700 BMP receptor binding(GO:0070700)
0.2 6.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 2.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 5.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 3.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 2.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 3.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 22.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.7 GO:0070905 serine binding(GO:0070905)
0.1 2.4 GO:0031005 filamin binding(GO:0031005)
0.1 6.6 GO:0019894 kinesin binding(GO:0019894)
0.1 1.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 4.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 2.1 GO:0005537 mannose binding(GO:0005537)
0.1 41.4 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 4.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 3.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.2 GO:0005112 Notch binding(GO:0005112)
0.1 12.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 14.2 GO:0004519 endonuclease activity(GO:0004519)
0.1 3.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.9 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 3.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 2.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.6 GO:0016015 morphogen activity(GO:0016015)
0.1 22.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 5.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 5.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.4 GO:0004697 protein kinase C activity(GO:0004697)
0.1 2.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.9 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.7 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 3.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 5.7 GO:0044325 ion channel binding(GO:0044325)
0.0 2.5 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 4.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 4.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 4.9 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 18.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.6 11.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.5 25.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.5 18.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 10.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 4.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 5.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 4.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 3.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 11.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 6.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 6.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 8.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 1.4 PID IGF1 PATHWAY IGF1 pathway
0.1 1.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 3.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 3.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 4.8 PID P73PATHWAY p73 transcription factor network
0.1 5.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 3.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 4.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 2.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 4.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 76.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.2 8.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.8 14.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.7 24.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 16.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.5 15.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 17.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 5.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 15.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 2.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 7.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 3.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 5.8 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 6.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 1.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.1 4.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 3.5 REACTOME KINESINS Genes involved in Kinesins
0.1 2.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 6.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 14.9 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 2.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 3.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 6.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 3.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 10.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 8.7 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 2.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 4.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 5.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 2.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 3.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 9.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.9 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 2.8 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.1 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 3.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 3.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 2.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation