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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for GGCUCAG

Z-value: 1.36

Motif logo

logo of

miRNA associated with seed GGCUCAG

NamemiRBASE accession
hsa-miR-24-3p
MIMAT0000080

Activity profile of GGCUCAG motif

Sorted Z-values of GGCUCAG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_24772455 15.75 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chrX_+_56259316 12.82 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr5_-_149535421 11.85 ENST00000261799.4
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chrX_-_18372792 11.53 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr17_-_8055747 10.87 ENST00000317276.4
ENST00000581703.1
PER1
period circadian clock 1
chr9_-_98079965 10.54 ENST00000289081.3
FANCC
Fanconi anemia, complementation group C
chr14_+_24583836 9.64 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11
DDB1 and CUL4 associated factor 11
chr17_-_7197881 8.87 ENST00000007699.5
YBX2
Y box binding protein 2
chr15_+_75287861 8.32 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
SCAMP5
secretory carrier membrane protein 5
chr9_+_37753795 8.03 ENST00000377753.2
ENST00000537911.1
ENST00000377754.2
ENST00000297994.3
TRMT10B
tRNA methyltransferase 10 homolog B (S. cerevisiae)
chr16_+_67927147 7.97 ENST00000291041.5
PSKH1
protein serine kinase H1
chr16_+_58497567 7.88 ENST00000258187.5
NDRG4
NDRG family member 4
chr11_-_22851367 7.87 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chr12_-_49504655 7.87 ENST00000551782.1
ENST00000267102.8
LMBR1L
limb development membrane protein 1-like
chr17_-_61777459 7.80 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr17_+_19281034 7.70 ENST00000308406.5
ENST00000299612.7
MAPK7
mitogen-activated protein kinase 7
chr1_+_156124162 7.63 ENST00000368282.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr14_-_77843390 7.55 ENST00000216468.7
TMED8
transmembrane emp24 protein transport domain containing 8
chr11_-_59383617 7.35 ENST00000263847.1
OSBP
oxysterol binding protein
chr7_-_44365020 7.27 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr16_+_66914264 7.21 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr16_+_11762270 7.18 ENST00000329565.5
SNN
stannin
chr11_-_1593150 7.10 ENST00000397374.3
DUSP8
dual specificity phosphatase 8
chr19_-_18632861 6.93 ENST00000262809.4
ELL
elongation factor RNA polymerase II
chr5_-_131826457 6.79 ENST00000437654.1
ENST00000245414.4
IRF1
interferon regulatory factor 1
chr1_-_200992827 6.74 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr17_+_20059302 6.70 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr7_+_138916231 6.67 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr9_-_130829588 6.62 ENST00000373078.4
NAIF1
nuclear apoptosis inducing factor 1
chrX_-_57937067 6.50 ENST00000358697.4
ZXDA
zinc finger, X-linked, duplicated A
chr1_-_207224307 6.44 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr6_-_44281043 6.40 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr2_-_175351744 6.39 ENST00000295500.4
ENST00000392552.2
ENST00000392551.2
GPR155
G protein-coupled receptor 155
chr1_+_27561007 6.38 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr5_+_65018017 5.70 ENST00000380985.5
ENST00000502464.1
NLN
neurolysin (metallopeptidase M3 family)
chr3_+_52444651 5.63 ENST00000327906.3
PHF7
PHD finger protein 7
chr3_+_49591881 5.62 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr1_+_210001309 5.61 ENST00000491415.2
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr8_+_22102626 5.58 ENST00000519237.1
ENST00000397802.4
POLR3D
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr14_+_61788429 5.52 ENST00000332981.5
PRKCH
protein kinase C, eta
chr17_-_2206801 5.49 ENST00000544865.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chrX_+_57618269 5.24 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chr19_+_41284121 5.19 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B
RAB4B, member RAS oncogene family
chr17_+_72744791 5.16 ENST00000583369.1
ENST00000262613.5
SLC9A3R1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
chr19_+_39616410 5.09 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr17_-_78450398 5.05 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr10_-_95360983 5.03 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr14_+_102027688 5.02 ENST00000510508.4
ENST00000359323.3
DIO3
deiodinase, iodothyronine, type III
chr1_+_101702417 5.02 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr10_+_102222798 4.98 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr15_+_65134088 4.87 ENST00000323544.4
ENST00000437723.1
PLEKHO2
AC069368.3
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr9_-_127269661 4.86 ENST00000373588.4
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr3_+_47324424 4.80 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18
kelch-like family member 18
chr9_-_72287191 4.61 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr1_-_203155868 4.54 ENST00000255409.3
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr22_+_42196666 4.54 ENST00000402061.3
ENST00000255784.5
CCDC134
coiled-coil domain containing 134
chr1_-_115212696 4.52 ENST00000393276.3
ENST00000393277.1
DENND2C
DENN/MADD domain containing 2C
chr2_-_217560248 4.51 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr5_-_140998616 4.51 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chr17_+_34431212 4.51 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr6_+_37137939 4.50 ENST00000373509.5
PIM1
pim-1 oncogene
chr5_+_137774706 4.50 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2
receptor accessory protein 2
chr11_-_119252359 4.44 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr19_+_18794470 4.37 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr11_-_61684962 4.34 ENST00000394836.2
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr1_-_236228403 4.29 ENST00000366595.3
NID1
nidogen 1
chr2_-_239197201 4.27 ENST00000254658.3
PER2
period circadian clock 2
chr14_-_100070363 4.25 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr6_+_157802165 4.24 ENST00000414563.2
ENST00000359775.5
ZDHHC14
zinc finger, DHHC-type containing 14
chr8_-_10588010 4.23 ENST00000304501.1
SOX7
SRY (sex determining region Y)-box 7
chr9_-_127533519 4.18 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr3_+_38537763 4.10 ENST00000287675.5
ENST00000358249.2
ENST00000422077.2
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr9_-_101471479 4.05 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr22_-_51066521 4.05 ENST00000395621.3
ENST00000395619.3
ENST00000356098.5
ENST00000216124.5
ENST00000453344.2
ENST00000547307.1
ENST00000547805.1
ARSA
arylsulfatase A
chr7_+_102004322 4.04 ENST00000496391.1
PRKRIP1
PRKR interacting protein 1 (IL11 inducible)
chr15_+_41851211 3.93 ENST00000263798.3
TYRO3
TYRO3 protein tyrosine kinase
chr17_-_39890893 3.91 ENST00000393939.2
ENST00000347901.4
ENST00000341193.5
ENST00000310778.5
HAP1
huntingtin-associated protein 1
chr13_-_28545276 3.91 ENST00000381020.7
CDX2
caudal type homeobox 2
chr8_-_134584152 3.86 ENST00000521180.1
ENST00000517668.1
ENST00000319914.5
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr4_-_17812309 3.78 ENST00000382247.1
ENST00000536863.1
DCAF16
DDB1 and CUL4 associated factor 16
chr11_-_2906979 3.78 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr2_+_29204161 3.73 ENST00000379558.4
ENST00000403861.2
FAM179A
family with sequence similarity 179, member A
chr5_-_149492904 3.65 ENST00000286301.3
ENST00000511344.1
CSF1R
colony stimulating factor 1 receptor
chr7_+_77325738 3.64 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr8_-_67579418 3.57 ENST00000310421.4
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr20_-_33680588 3.55 ENST00000451813.2
ENST00000432634.2
TRPC4AP
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr22_+_31742875 3.47 ENST00000504184.2
AC005003.1
CDNA FLJ20464 fis, clone KAT06158; HCG1777549; Uncharacterized protein
chr16_-_67840442 3.47 ENST00000536251.1
ENST00000448631.2
ENST00000602677.1
ENST00000411657.2
ENST00000425512.2
ENST00000317506.3
RANBP10
RAN binding protein 10
chr11_-_6677018 3.43 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr10_-_74114714 3.39 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DNAJB12
DnaJ (Hsp40) homolog, subfamily B, member 12
chr2_+_113931513 3.36 ENST00000245796.6
ENST00000441564.3
PSD4
pleckstrin and Sec7 domain containing 4
chr10_-_50323543 3.36 ENST00000332853.4
ENST00000298454.3
VSTM4
V-set and transmembrane domain containing 4
chr2_-_69870835 3.32 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr17_-_9929581 3.30 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr11_+_43380459 3.29 ENST00000299240.6
ENST00000039989.4
TTC17
tetratricopeptide repeat domain 17
chr8_+_26240414 3.21 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr11_-_117186946 3.20 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1
chr10_-_81205373 3.20 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr15_+_42066632 3.18 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr15_-_34628951 3.15 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chrX_-_65858865 3.15 ENST00000374719.3
ENST00000450752.1
ENST00000451436.2
EDA2R
ectodysplasin A2 receptor
chr5_+_139493665 3.10 ENST00000331327.3
PURA
purine-rich element binding protein A
chr17_-_72889697 3.05 ENST00000310226.6
FADS6
fatty acid desaturase 6
chr10_-_105615164 3.04 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr1_+_27114418 3.03 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr9_-_131534160 2.97 ENST00000291900.2
ZER1
zyg-11 related, cell cycle regulator
chr13_-_21476900 2.95 ENST00000400602.2
ENST00000255305.6
XPO4
exportin 4
chr19_-_16682987 2.94 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
SLC35E1
solute carrier family 35, member E1
chr20_-_48099182 2.94 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chrX_+_21857717 2.93 ENST00000379484.5
MBTPS2
membrane-bound transcription factor peptidase, site 2
chr5_-_115910630 2.92 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_-_49393092 2.85 ENST00000421952.2
DDN
dendrin
chr18_+_43914159 2.84 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165
ring finger protein 165
chr17_-_27916621 2.83 ENST00000225394.3
GIT1
G protein-coupled receptor kinase interacting ArfGAP 1
chr1_-_2145620 2.77 ENST00000545087.1
AL590822.1
Uncharacterized protein
chr2_-_109605663 2.76 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr10_-_128077024 2.75 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
ADAM12
ADAM metallopeptidase domain 12
chrX_+_107334895 2.74 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr17_-_79885576 2.73 ENST00000574686.1
ENST00000357736.4
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr2_-_37193606 2.72 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr9_+_91933407 2.70 ENST00000375807.3
ENST00000339901.4
SECISBP2
SECIS binding protein 2
chr6_+_37225540 2.69 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr22_-_19279201 2.65 ENST00000353891.5
ENST00000263200.10
ENST00000427926.1
ENST00000449918.1
CLTCL1
clathrin, heavy chain-like 1
chr3_-_50396978 2.63 ENST00000266025.3
TMEM115
transmembrane protein 115
chr3_-_126194707 2.61 ENST00000336332.5
ENST00000389709.3
ZXDC
ZXD family zinc finger C
chr12_+_74931551 2.60 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr5_-_112630598 2.52 ENST00000302475.4
MCC
mutated in colorectal cancers
chr14_+_102829300 2.49 ENST00000359520.7
TECPR2
tectonin beta-propeller repeat containing 2
chr11_-_62599505 2.48 ENST00000377897.4
ENST00000394690.1
ENST00000541317.1
ENST00000294179.3
STX5
syntaxin 5
chr12_-_48152428 2.47 ENST00000449771.2
ENST00000395358.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr2_-_113542063 2.46 ENST00000263339.3
IL1A
interleukin 1, alpha
chr9_+_102668915 2.45 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr3_-_120068143 2.45 ENST00000295628.3
LRRC58
leucine rich repeat containing 58
chr17_+_1958388 2.42 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr15_+_91411810 2.42 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr3_-_178790057 2.42 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr7_+_31092076 2.40 ENST00000304166.4
ADCYAP1R1
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
chr22_-_37545972 2.35 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr17_+_60704762 2.34 ENST00000303375.5
MRC2
mannose receptor, C type 2
chr7_-_44924939 2.29 ENST00000395699.2
PURB
purine-rich element binding protein B
chr1_+_55464600 2.28 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr5_-_131347306 2.26 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
ACSL6
acyl-CoA synthetase long-chain family member 6
chr8_+_23104130 2.26 ENST00000313219.7
ENST00000519984.1
CHMP7
charged multivesicular body protein 7
chr10_+_102295616 2.19 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr2_+_111878483 2.18 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr12_-_53625958 2.17 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr19_+_34745442 2.13 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355
KIAA0355
chr17_-_5372271 2.11 ENST00000225296.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr16_-_4292071 2.09 ENST00000399609.3
SRL
sarcalumenin
chr17_+_33307503 2.08 ENST00000378526.4
ENST00000585941.1
ENST00000262327.5
ENST00000592690.1
ENST00000585740.1
LIG3
ligase III, DNA, ATP-dependent
chr11_+_45868957 2.03 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr2_-_70995307 2.01 ENST00000264436.4
ENST00000355733.3
ENST00000447731.2
ENST00000430656.1
ENST00000413157.2
ADD2
adducin 2 (beta)
chr13_+_98086445 2.00 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr1_-_46598284 2.00 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr2_+_102759199 1.98 ENST00000409288.1
ENST00000410023.1
IL1R1
interleukin 1 receptor, type I
chr10_-_99161033 1.97 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr2_+_206547215 1.94 ENST00000360409.3
ENST00000540178.1
ENST00000540841.1
ENST00000355117.4
ENST00000450507.1
ENST00000417189.1
NRP2
neuropilin 2
chr22_+_38004473 1.89 ENST00000414350.3
ENST00000343632.4
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr3_-_114790179 1.89 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_105630016 1.88 ENST00000258530.3
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr7_-_17980091 1.84 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13
sorting nexin 13
chr5_+_40679584 1.84 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr17_-_42345487 1.84 ENST00000262418.6
SLC4A1
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr1_-_161102421 1.83 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
DEDD
death effector domain containing
chr16_-_279405 1.82 ENST00000430864.1
ENST00000293872.8
ENST00000337351.4
ENST00000397783.1
LUC7L
LUC7-like (S. cerevisiae)
chr20_+_34700333 1.82 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr20_+_1875110 1.80 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr22_-_42466782 1.79 ENST00000396398.3
ENST00000403363.1
ENST00000402937.1
NAGA
N-acetylgalactosaminidase, alpha-
chr1_+_118148556 1.77 ENST00000369448.3
FAM46C
family with sequence similarity 46, member C
chr6_+_106546808 1.77 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr12_+_124196865 1.75 ENST00000330342.3
ATP6V0A2
ATPase, H+ transporting, lysosomal V0 subunit a2
chr18_+_63418068 1.67 ENST00000397968.2
CDH7
cadherin 7, type 2
chr11_-_10590238 1.67 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr1_-_151119087 1.65 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr6_-_109762344 1.64 ENST00000521072.2
ENST00000424445.2
ENST00000440797.2
PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr5_+_135468516 1.63 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr11_-_6624801 1.63 ENST00000534343.1
ENST00000254605.6
RRP8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr16_-_31147020 1.62 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr2_-_86564776 1.62 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr10_+_76586348 1.61 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr13_+_58206655 1.60 ENST00000377918.3
PCDH17
protocadherin 17
chr3_+_88188254 1.60 ENST00000309495.5
ZNF654
zinc finger protein 654
chr3_-_56502375 1.59 ENST00000288221.6
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr17_+_12692774 1.51 ENST00000379672.5
ENST00000340825.3
ARHGAP44
Rho GTPase activating protein 44
chr6_-_90529418 1.50 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1
MDN1, midasin homolog (yeast)
chr2_-_182545603 1.49 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr16_-_4166186 1.47 ENST00000294016.3
ADCY9
adenylate cyclase 9
chr12_+_53774423 1.46 ENST00000426431.2
SP1
Sp1 transcription factor
chr4_+_1795012 1.45 ENST00000481110.2
ENST00000340107.4
ENST00000440486.2
ENST00000412135.2
FGFR3
fibroblast growth factor receptor 3
chrX_-_100548045 1.44 ENST00000372907.3
ENST00000372905.2
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr14_-_77279153 1.44 ENST00000251089.2
ANGEL1
angel homolog 1 (Drosophila)
chr1_-_153919128 1.41 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr11_-_108093329 1.40 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr19_+_45754505 1.37 ENST00000262891.4
ENST00000300843.4
MARK4
MAP/microtubule affinity-regulating kinase 4
chr17_+_68165657 1.36 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr12_-_123450986 1.36 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr11_+_66025167 1.34 ENST00000394067.2
ENST00000316924.5
ENST00000421552.1
ENST00000394078.1
KLC2
kinesin light chain 2
chr9_-_117692697 1.34 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr4_+_55095264 1.33 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr21_+_45285050 1.31 ENST00000291572.8
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of GGCUCAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.7 GO:0033693 neurofilament bundle assembly(GO:0033693)
4.4 13.2 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.6 7.9 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
2.2 8.9 GO:0009386 translational attenuation(GO:0009386)
2.2 12.9 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
2.1 6.4 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
2.1 6.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
2.0 8.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.9 5.7 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.7 6.8 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
1.7 10.2 GO:0030820 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121)
1.7 5.0 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
1.6 6.3 GO:0032899 regulation of neurotrophin production(GO:0032899)
1.5 4.5 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.5 4.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
1.5 4.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.3 3.9 GO:0014807 regulation of somitogenesis(GO:0014807)
1.3 5.2 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
1.2 4.9 GO:0007538 primary sex determination(GO:0007538)
1.1 3.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
1.1 2.2 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
1.1 2.2 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
1.0 5.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.9 2.7 GO:0051697 protein delipidation(GO:0051697)
0.9 4.3 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.8 3.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.8 3.0 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.8 4.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.7 4.4 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.7 2.9 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.7 5.0 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.7 3.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.7 2.1 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.7 5.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.7 0.7 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.6 1.9 GO:0097491 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.6 3.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.6 1.8 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.6 5.5 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.6 7.9 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.5 2.2 GO:0070384 Harderian gland development(GO:0070384)
0.5 3.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.5 0.5 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.5 10.9 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.5 2.5 GO:0016240 autophagosome docking(GO:0016240)
0.5 2.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.5 7.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.5 4.5 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.4 5.0 GO:0048263 determination of dorsal identity(GO:0048263)
0.4 1.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.4 4.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4 3.7 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145) cell-cell junction maintenance(GO:0045217)
0.4 7.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.4 1.6 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.4 0.8 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.4 1.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.4 1.5 GO:0035881 amacrine cell differentiation(GO:0035881) intestinal epithelial structure maintenance(GO:0060729)
0.4 2.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 1.8 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.3 4.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 8.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.3 1.4 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 4.6 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.3 3.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 7.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.3 2.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 8.0 GO:0030488 tRNA methylation(GO:0030488)
0.3 4.4 GO:0045475 locomotor rhythm(GO:0045475)
0.3 1.2 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.3 2.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.3 2.9 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 3.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 1.6 GO:0001880 Mullerian duct regression(GO:0001880)
0.3 6.2 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.3 4.2 GO:0018345 protein palmitoylation(GO:0018345)
0.3 1.0 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 5.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 1.5 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.2 2.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 3.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 1.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 1.6 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.2 1.4 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.2 3.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 2.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 2.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.2 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 7.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 2.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.2 0.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 0.7 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 1.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 3.9 GO:0060384 innervation(GO:0060384)
0.2 0.3 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2 3.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 3.9 GO:0097503 sialylation(GO:0097503)
0.1 7.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 4.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.6 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 5.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 3.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 3.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 3.8 GO:0060065 uterus development(GO:0060065)
0.1 0.4 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 1.2 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 2.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 1.2 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 2.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 2.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 2.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 6.6 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.1 0.9 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 2.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 1.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 5.6 GO:0035418 protein localization to synapse(GO:0035418)
0.1 4.2 GO:0001706 endoderm formation(GO:0001706)
0.1 0.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 2.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 2.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.8 GO:0051597 response to methylmercury(GO:0051597)
0.1 8.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 3.2 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 2.0 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 1.5 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.2 GO:0045109 intermediate filament organization(GO:0045109)
0.1 5.1 GO:0060996 dendritic spine development(GO:0060996)
0.1 0.8 GO:0033572 transferrin transport(GO:0033572)
0.1 1.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.6 GO:0045176 apical protein localization(GO:0045176)
0.1 4.8 GO:0030641 regulation of cellular pH(GO:0030641)
0.1 0.2 GO:0003360 brainstem development(GO:0003360)
0.1 2.4 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 4.1 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.1 1.1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 5.6 GO:0021987 cerebral cortex development(GO:0021987)
0.1 3.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 1.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.6 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 6.7 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.7 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 2.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 1.9 GO:1901998 toxin transport(GO:1901998)
0.0 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 6.0 GO:0044782 cilium organization(GO:0044782)
0.0 0.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.6 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 2.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 1.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 4.0 GO:0003014 renal system process(GO:0003014)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.0 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 1.8 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 1.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.5 GO:0014002 astrocyte development(GO:0014002)
0.0 0.4 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 3.1 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 2.4 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 11.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
1.4 5.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
1.4 4.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
1.1 10.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.0 15.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.6 5.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.6 1.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.6 3.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.6 3.0 GO:0031501 mannosyltransferase complex(GO:0031501)
0.5 4.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 1.3 GO:0016938 kinesin I complex(GO:0016938)
0.4 3.0 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.4 12.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.4 5.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 1.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 2.7 GO:0071439 clathrin complex(GO:0071439)
0.3 2.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 8.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 5.2 GO:0097225 sperm midpiece(GO:0097225)
0.2 12.8 GO:0016235 aggresome(GO:0016235)
0.2 5.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 3.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 1.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 2.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 2.6 GO:0017119 Golgi transport complex(GO:0017119)
0.2 9.1 GO:0048786 presynaptic active zone(GO:0048786)
0.2 5.6 GO:0032040 small-subunit processome(GO:0032040)
0.2 1.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 2.3 GO:0000815 ESCRT III complex(GO:0000815)
0.2 1.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 2.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 6.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.9 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 5.3 GO:0005871 kinesin complex(GO:0005871)
0.1 7.5 GO:0031519 PcG protein complex(GO:0031519)
0.1 7.0 GO:0031201 SNARE complex(GO:0031201)
0.1 3.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.8 GO:0043196 varicosity(GO:0043196)
0.1 1.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 5.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.8 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.0 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 4.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 6.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 8.9 GO:0016605 PML body(GO:0016605)
0.1 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 1.6 GO:0071141 SMAD protein complex(GO:0071141)
0.1 5.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 10.0 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.0 GO:0043194 axon initial segment(GO:0043194)
0.1 3.5 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.1 1.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 11.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 7.9 GO:0005795 Golgi stack(GO:0005795)
0.1 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 3.1 GO:0043195 terminal bouton(GO:0043195)
0.0 5.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 8.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 4.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 6.5 GO:0030133 transport vesicle(GO:0030133)
0.0 2.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 10.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 10.4 GO:0016607 nuclear speck(GO:0016607)
0.0 6.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 7.1 GO:0000785 chromatin(GO:0000785)
0.0 19.3 GO:0005730 nucleolus(GO:0005730)
0.0 1.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 4.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.7 GO:0016604 nuclear body(GO:0016604)
0.0 1.5 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 3.7 GO:0005813 centrosome(GO:0005813)
0.0 0.7 GO:1902554 serine/threonine protein kinase complex(GO:1902554)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
2.1 6.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
2.1 6.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
1.4 4.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.2 7.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.1 5.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.1 3.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.1 7.4 GO:0008142 oxysterol binding(GO:0008142)
1.0 3.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.9 5.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.8 5.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.8 3.0 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.7 4.3 GO:0043237 laminin-1 binding(GO:0043237)
0.7 8.0 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.6 4.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.6 2.4 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.6 3.9 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.5 2.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.5 2.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.5 7.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 7.9 GO:0038191 neuropilin binding(GO:0038191)
0.4 2.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.4 5.2 GO:0045159 myosin II binding(GO:0045159)
0.4 5.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036) sphingolipid binding(GO:0046625)
0.4 4.5 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.4 4.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 1.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.3 4.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.3 1.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.3 5.0 GO:0016918 retinal binding(GO:0016918)
0.3 4.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 2.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 3.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 3.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 2.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 4.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 3.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 9.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 4.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 3.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.3 6.1 GO:0004707 MAP kinase activity(GO:0004707)
0.3 2.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 1.8 GO:0050733 RS domain binding(GO:0050733)
0.2 1.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 5.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 2.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 3.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 2.1 GO:0000182 rDNA binding(GO:0000182)
0.2 1.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 4.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.2 3.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.7 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.2 1.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 2.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.2 12.4 GO:0070888 E-box binding(GO:0070888)
0.2 5.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 0.6 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.2 10.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 5.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.2 0.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 2.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 2.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.8 GO:0015925 galactosidase activity(GO:0015925)
0.2 3.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 7.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 2.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 2.0 GO:0009881 photoreceptor activity(GO:0009881)
0.1 1.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 7.9 GO:0043621 protein self-association(GO:0043621)
0.1 0.4 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 2.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 11.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.6 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.6 GO:0052841 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 1.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 19.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.1 GO:0043495 protein anchor(GO:0043495)
0.1 0.7 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 8.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 11.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 6.7 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 2.0 GO:0030507 spectrin binding(GO:0030507)
0.1 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.2 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.5 GO:0005109 frizzled binding(GO:0005109)
0.1 3.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 1.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 15.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 10.3 GO:0019902 phosphatase binding(GO:0019902)
0.1 1.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.7 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.1 1.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.5 GO:0030552 cAMP binding(GO:0030552)
0.1 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 3.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 4.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 6.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 3.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 1.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 2.2 GO:0002039 p53 binding(GO:0002039)
0.0 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 4.9 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.0 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 11.3 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 17.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.5 16.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.4 3.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3 16.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 12.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 5.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 4.5 PID IL5 PATHWAY IL5-mediated signaling events
0.2 4.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 4.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 6.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 11.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 2.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 5.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 6.5 PID FGF PATHWAY FGF signaling pathway
0.1 5.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.6 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 2.5 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 10.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 5.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 8.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.1 SIG CHEMOTAXIS Genes related to chemotaxis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.5 10.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 7.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 11.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.4 4.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 7.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.3 17.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 6.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 5.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 4.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 5.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 6.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 5.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 3.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 6.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 2.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 6.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 4.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.9 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.2 3.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 1.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 6.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 11.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 2.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 2.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 5.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.7 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.1 4.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 3.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 7.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 1.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 6.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.3 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 5.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 5.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 3.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction