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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for GTF2I
Z-value: 0.08
Motif logo
Transcription factors associated with GTF2I
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
GTF2I
|
ENSG00000077809.8 | general transcription factor IIi |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GTF2I | hg19_v2_chr7_+_74072011_74072119 | 0.44 | 1.4e-11 | Click! |
Activity profile of GTF2I motif
Sorted Z-values of GTF2I motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_+_23775971 | 14.92 |
ENST00000250405.5
|
BCL2L2
|
BCL2-like 2 |
| chr1_+_169075554 | 13.63 |
ENST00000367815.4
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide |
| chr1_+_169077172 | 13.28 |
ENST00000499679.3
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide |
| chr15_-_37392703 | 12.90 |
ENST00000382766.2
ENST00000444725.1 |
MEIS2
|
Meis homeobox 2 |
| chrX_+_102631844 | 10.65 |
ENST00000372634.1
ENST00000299872.7 |
NGFRAP1
|
nerve growth factor receptor (TNFRSF16) associated protein 1 |
| chr22_-_36236265 | 10.16 |
ENST00000414461.2
ENST00000416721.2 ENST00000449924.2 ENST00000262829.7 ENST00000397305.3 |
RBFOX2
|
RNA binding protein, fox-1 homolog (C. elegans) 2 |
| chr1_-_20812690 | 10.06 |
ENST00000375078.3
|
CAMK2N1
|
calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| chr4_-_16900242 | 9.76 |
ENST00000502640.1
ENST00000506732.1 |
LDB2
|
LIM domain binding 2 |
| chr12_-_16759711 | 9.62 |
ENST00000447609.1
|
LMO3
|
LIM domain only 3 (rhombotin-like 2) |
| chr12_-_45270151 | 8.98 |
ENST00000429094.2
|
NELL2
|
NEL-like 2 (chicken) |
| chr5_+_92919043 | 8.64 |
ENST00000327111.3
|
NR2F1
|
nuclear receptor subfamily 2, group F, member 1 |
| chr12_-_45270077 | 8.60 |
ENST00000551601.1
ENST00000549027.1 ENST00000452445.2 |
NELL2
|
NEL-like 2 (chicken) |
| chr4_-_16900410 | 8.59 |
ENST00000304523.5
|
LDB2
|
LIM domain binding 2 |
| chr6_-_29600832 | 8.09 |
ENST00000377016.4
ENST00000376977.3 ENST00000377034.4 |
GABBR1
|
gamma-aminobutyric acid (GABA) B receptor, 1 |
| chr4_-_16900217 | 8.05 |
ENST00000441778.2
|
LDB2
|
LIM domain binding 2 |
| chr15_-_37392086 | 7.85 |
ENST00000561208.1
|
MEIS2
|
Meis homeobox 2 |
| chr1_+_164528866 | 7.69 |
ENST00000420696.2
|
PBX1
|
pre-B-cell leukemia homeobox 1 |
| chr8_+_26371763 | 7.69 |
ENST00000521913.1
|
DPYSL2
|
dihydropyrimidinase-like 2 |
| chr2_+_159313452 | 7.61 |
ENST00000389757.3
ENST00000389759.3 |
PKP4
|
plakophilin 4 |
| chr8_-_30670053 | 7.56 |
ENST00000518564.1
|
PPP2CB
|
protein phosphatase 2, catalytic subunit, beta isozyme |
| chr17_+_2496971 | 7.21 |
ENST00000397195.5
|
PAFAH1B1
|
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| chr4_-_16900184 | 6.98 |
ENST00000515064.1
|
LDB2
|
LIM domain binding 2 |
| chr15_-_73925651 | 6.90 |
ENST00000545878.1
ENST00000287226.8 ENST00000345330.4 |
NPTN
|
neuroplastin |
| chr7_+_69064300 | 6.88 |
ENST00000342771.4
|
AUTS2
|
autism susceptibility candidate 2 |
| chr1_-_68698222 | 6.69 |
ENST00000370976.3
ENST00000354777.2 ENST00000262348.4 ENST00000540432.1 |
WLS
|
wntless Wnt ligand secretion mediator |
| chrX_-_134156502 | 6.55 |
ENST00000391440.1
|
FAM127C
|
family with sequence similarity 127, member C |
| chr5_+_138629389 | 6.54 |
ENST00000504045.1
ENST00000504311.1 ENST00000502499.1 |
MATR3
|
matrin 3 |
| chr6_+_30852130 | 6.39 |
ENST00000428153.2
ENST00000376568.3 ENST00000452441.1 ENST00000515219.1 |
DDR1
|
discoidin domain receptor tyrosine kinase 1 |
| chr2_+_54683419 | 6.26 |
ENST00000356805.4
|
SPTBN1
|
spectrin, beta, non-erythrocytic 1 |
| chr4_-_176923483 | 6.11 |
ENST00000280187.7
ENST00000512509.1 |
GPM6A
|
glycoprotein M6A |
| chr19_+_35629702 | 6.07 |
ENST00000351325.4
|
FXYD1
|
FXYD domain containing ion transport regulator 1 |
| chr1_-_95391315 | 5.88 |
ENST00000545882.1
ENST00000415017.1 |
CNN3
|
calponin 3, acidic |
| chr13_-_36705425 | 5.82 |
ENST00000255448.4
ENST00000360631.3 ENST00000379892.4 |
DCLK1
|
doublecortin-like kinase 1 |
| chr12_+_110718921 | 5.81 |
ENST00000308664.6
|
ATP2A2
|
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| chr6_+_114178512 | 5.80 |
ENST00000368635.4
|
MARCKS
|
myristoylated alanine-rich protein kinase C substrate |
| chr1_+_27022839 | 5.79 |
ENST00000457599.2
|
ARID1A
|
AT rich interactive domain 1A (SWI-like) |
| chrX_+_118370288 | 5.78 |
ENST00000535419.1
|
PGRMC1
|
progesterone receptor membrane component 1 |
| chr11_-_72385437 | 5.70 |
ENST00000418754.2
ENST00000542969.2 ENST00000334456.5 |
PDE2A
|
phosphodiesterase 2A, cGMP-stimulated |
| chr13_-_45150392 | 5.63 |
ENST00000501704.2
|
TSC22D1
|
TSC22 domain family, member 1 |
| chr7_+_100770328 | 5.50 |
ENST00000223095.4
ENST00000445463.2 |
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| chr2_+_62933001 | 5.49 |
ENST00000263991.5
ENST00000354487.3 |
EHBP1
|
EH domain binding protein 1 |
| chr19_+_35630022 | 5.47 |
ENST00000589209.1
|
FXYD1
|
FXYD domain containing ion transport regulator 1 |
| chr11_-_125366089 | 5.21 |
ENST00000366139.3
ENST00000278919.3 |
FEZ1
|
fasciculation and elongation protein zeta 1 (zygin I) |
| chr14_-_60337684 | 5.13 |
ENST00000267484.5
|
RTN1
|
reticulon 1 |
| chr2_-_56150910 | 5.09 |
ENST00000424836.2
ENST00000438672.1 ENST00000440439.1 ENST00000429909.1 ENST00000424207.1 ENST00000452337.1 ENST00000355426.3 ENST00000439193.1 ENST00000421664.1 |
EFEMP1
|
EGF containing fibulin-like extracellular matrix protein 1 |
| chr5_+_138629417 | 5.02 |
ENST00000510056.1
ENST00000511249.1 ENST00000503811.1 ENST00000511378.1 |
MATR3
|
matrin 3 |
| chr6_+_43739697 | 5.00 |
ENST00000230480.6
|
VEGFA
|
vascular endothelial growth factor A |
| chr14_-_23822061 | 4.82 |
ENST00000397260.3
|
SLC22A17
|
solute carrier family 22, member 17 |
| chr1_+_160175117 | 4.79 |
ENST00000360472.4
|
PEA15
|
phosphoprotein enriched in astrocytes 15 |
| chrX_+_118370211 | 4.78 |
ENST00000217971.7
|
PGRMC1
|
progesterone receptor membrane component 1 |
| chr14_-_23822080 | 4.71 |
ENST00000397267.1
ENST00000354772.3 |
SLC22A17
|
solute carrier family 22, member 17 |
| chr8_+_97506033 | 4.70 |
ENST00000518385.1
|
SDC2
|
syndecan 2 |
| chr1_+_160175201 | 4.69 |
ENST00000368076.1
|
PEA15
|
phosphoprotein enriched in astrocytes 15 |
| chr7_+_121513143 | 4.69 |
ENST00000393386.2
|
PTPRZ1
|
protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
| chr1_+_87797351 | 4.68 |
ENST00000370542.1
|
LMO4
|
LIM domain only 4 |
| chr16_-_65155979 | 4.67 |
ENST00000562325.1
ENST00000268603.4 |
CDH11
|
cadherin 11, type 2, OB-cadherin (osteoblast) |
| chr15_-_37393406 | 4.58 |
ENST00000338564.5
ENST00000558313.1 ENST00000340545.5 |
MEIS2
|
Meis homeobox 2 |
| chr12_-_45269430 | 4.46 |
ENST00000395487.2
|
NELL2
|
NEL-like 2 (chicken) |
| chr17_-_15165854 | 4.44 |
ENST00000395936.1
ENST00000395938.2 |
PMP22
|
peripheral myelin protein 22 |
| chr2_-_227664474 | 4.44 |
ENST00000305123.5
|
IRS1
|
insulin receptor substrate 1 |
| chr20_-_49547910 | 4.42 |
ENST00000396032.3
|
ADNP
|
activity-dependent neuroprotector homeobox |
| chr1_+_64059332 | 4.35 |
ENST00000540265.1
|
PGM1
|
phosphoglucomutase 1 |
| chr5_+_138089100 | 4.35 |
ENST00000520339.1
ENST00000355078.5 ENST00000302763.7 ENST00000518910.1 |
CTNNA1
|
catenin (cadherin-associated protein), alpha 1, 102kDa |
| chr14_-_103987679 | 4.33 |
ENST00000553610.1
|
CKB
|
creatine kinase, brain |
| chr2_+_182756615 | 4.31 |
ENST00000431877.2
ENST00000320370.7 |
SSFA2
|
sperm specific antigen 2 |
| chr9_+_87284622 | 4.30 |
ENST00000395882.1
|
NTRK2
|
neurotrophic tyrosine kinase, receptor, type 2 |
| chr1_-_244013384 | 4.30 |
ENST00000366539.1
|
AKT3
|
v-akt murine thymoma viral oncogene homolog 3 |
| chr1_+_86046433 | 4.27 |
ENST00000451137.2
|
CYR61
|
cysteine-rich, angiogenic inducer, 61 |
| chr4_-_157892498 | 4.26 |
ENST00000502773.1
|
PDGFC
|
platelet derived growth factor C |
| chr1_-_68299130 | 4.25 |
ENST00000370982.3
|
GNG12
|
guanine nucleotide binding protein (G protein), gamma 12 |
| chr8_+_104152922 | 4.22 |
ENST00000309982.5
ENST00000438105.2 ENST00000297574.6 |
BAALC
|
brain and acute leukemia, cytoplasmic |
| chr4_+_41361616 | 4.22 |
ENST00000513024.1
|
LIMCH1
|
LIM and calponin homology domains 1 |
| chr5_+_138629337 | 4.20 |
ENST00000394805.3
ENST00000512876.1 ENST00000513678.1 |
MATR3
|
matrin 3 |
| chr14_-_21491305 | 4.16 |
ENST00000554531.1
|
NDRG2
|
NDRG family member 2 |
| chr12_+_12870055 | 4.14 |
ENST00000228872.4
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| chr5_-_111092930 | 4.06 |
ENST00000257435.7
|
NREP
|
neuronal regeneration related protein |
| chr17_-_36891830 | 4.04 |
ENST00000578487.1
|
PCGF2
|
polycomb group ring finger 2 |
| chr20_-_49547731 | 4.03 |
ENST00000396029.3
|
ADNP
|
activity-dependent neuroprotector homeobox |
| chr1_+_166808692 | 4.03 |
ENST00000367876.4
|
POGK
|
pogo transposable element with KRAB domain |
| chr15_+_22892663 | 4.01 |
ENST00000313077.7
ENST00000561274.1 ENST00000560848.1 |
CYFIP1
|
cytoplasmic FMR1 interacting protein 1 |
| chr3_+_105085734 | 3.99 |
ENST00000306107.5
|
ALCAM
|
activated leukocyte cell adhesion molecule |
| chr2_-_39664405 | 3.99 |
ENST00000341681.5
ENST00000263881.3 |
MAP4K3
|
mitogen-activated protein kinase kinase kinase kinase 3 |
| chr12_+_107168342 | 3.98 |
ENST00000392837.4
|
RIC8B
|
RIC8 guanine nucleotide exchange factor B |
| chr14_+_32546485 | 3.91 |
ENST00000345122.3
ENST00000432921.1 ENST00000433497.1 |
ARHGAP5
|
Rho GTPase activating protein 5 |
| chr3_+_115342159 | 3.90 |
ENST00000305124.6
|
GAP43
|
growth associated protein 43 |
| chr1_-_68698197 | 3.86 |
ENST00000370973.2
ENST00000370971.1 |
WLS
|
wntless Wnt ligand secretion mediator |
| chr20_+_10199468 | 3.85 |
ENST00000254976.2
ENST00000304886.2 |
SNAP25
|
synaptosomal-associated protein, 25kDa |
| chr3_+_105086056 | 3.83 |
ENST00000472644.2
|
ALCAM
|
activated leukocyte cell adhesion molecule |
| chr2_-_55277436 | 3.82 |
ENST00000354474.6
|
RTN4
|
reticulon 4 |
| chr9_+_133320301 | 3.82 |
ENST00000352480.5
|
ASS1
|
argininosuccinate synthase 1 |
| chr3_+_115342349 | 3.80 |
ENST00000393780.3
|
GAP43
|
growth associated protein 43 |
| chr5_+_140772381 | 3.79 |
ENST00000398604.2
|
PCDHGA8
|
protocadherin gamma subfamily A, 8 |
| chr6_+_19837592 | 3.78 |
ENST00000378700.3
|
ID4
|
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| chr5_-_73936451 | 3.78 |
ENST00000537006.1
|
ENC1
|
ectodermal-neural cortex 1 (with BTB domain) |
| chr1_+_10271674 | 3.76 |
ENST00000377086.1
|
KIF1B
|
kinesin family member 1B |
| chr7_+_6414128 | 3.73 |
ENST00000348035.4
ENST00000356142.4 |
RAC1
|
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
| chr9_+_137967366 | 3.64 |
ENST00000252854.4
|
OLFM1
|
olfactomedin 1 |
| chr6_-_6007200 | 3.63 |
ENST00000244766.2
|
NRN1
|
neuritin 1 |
| chr6_-_52860171 | 3.60 |
ENST00000370963.4
|
GSTA4
|
glutathione S-transferase alpha 4 |
| chr2_+_36582857 | 3.56 |
ENST00000280527.2
|
CRIM1
|
cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| chr5_+_71403061 | 3.53 |
ENST00000512974.1
ENST00000296755.7 |
MAP1B
|
microtubule-associated protein 1B |
| chr10_-_15413035 | 3.53 |
ENST00000378116.4
ENST00000455654.1 |
FAM171A1
|
family with sequence similarity 171, member A1 |
| chr19_-_49149553 | 3.48 |
ENST00000084798.4
|
CA11
|
carbonic anhydrase XI |
| chr6_-_52859968 | 3.47 |
ENST00000370959.1
|
GSTA4
|
glutathione S-transferase alpha 4 |
| chr9_+_126773880 | 3.45 |
ENST00000373615.4
|
LHX2
|
LIM homeobox 2 |
| chr16_+_15528332 | 3.43 |
ENST00000566490.1
|
C16orf45
|
chromosome 16 open reading frame 45 |
| chr19_+_40854559 | 3.42 |
ENST00000598962.1
ENST00000409419.1 ENST00000409587.1 ENST00000602131.1 ENST00000409735.4 ENST00000600948.1 ENST00000356508.5 ENST00000596682.1 ENST00000594908.1 |
PLD3
|
phospholipase D family, member 3 |
| chr1_-_87380002 | 3.41 |
ENST00000331835.5
|
SEP15
|
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA. |
| chr17_+_45727204 | 3.40 |
ENST00000290158.4
|
KPNB1
|
karyopherin (importin) beta 1 |
| chr5_-_111093167 | 3.40 |
ENST00000446294.2
ENST00000419114.2 |
NREP
|
neuronal regeneration related protein |
| chr9_-_139940608 | 3.38 |
ENST00000371601.4
|
NPDC1
|
neural proliferation, differentiation and control, 1 |
| chr11_+_63742050 | 3.38 |
ENST00000314133.3
ENST00000535431.1 |
COX8A
AP000721.4
|
cytochrome c oxidase subunit VIIIA (ubiquitous) Uncharacterized protein |
| chr18_+_46065393 | 3.35 |
ENST00000256413.3
|
CTIF
|
CBP80/20-dependent translation initiation factor |
| chr1_+_64058939 | 3.31 |
ENST00000371084.3
|
PGM1
|
phosphoglucomutase 1 |
| chr19_-_2015699 | 3.31 |
ENST00000255608.4
|
BTBD2
|
BTB (POZ) domain containing 2 |
| chr14_+_32546274 | 3.28 |
ENST00000396582.2
|
ARHGAP5
|
Rho GTPase activating protein 5 |
| chr2_-_200322723 | 3.27 |
ENST00000417098.1
|
SATB2
|
SATB homeobox 2 |
| chr17_-_1303462 | 3.23 |
ENST00000573026.1
ENST00000575977.1 ENST00000571732.1 ENST00000264335.8 |
YWHAE
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| chr15_+_49170083 | 3.21 |
ENST00000530028.2
|
EID1
|
EP300 interacting inhibitor of differentiation 1 |
| chr2_-_55277692 | 3.21 |
ENST00000394611.2
|
RTN4
|
reticulon 4 |
| chr12_+_56473628 | 3.20 |
ENST00000549282.1
ENST00000549061.1 ENST00000267101.3 |
ERBB3
|
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 |
| chr17_+_35851570 | 3.19 |
ENST00000394386.1
|
DUSP14
|
dual specificity phosphatase 14 |
| chr9_-_14314066 | 3.18 |
ENST00000397575.3
|
NFIB
|
nuclear factor I/B |
| chr6_-_16761678 | 3.18 |
ENST00000244769.4
ENST00000436367.1 |
ATXN1
|
ataxin 1 |
| chr6_+_30850697 | 3.15 |
ENST00000509639.1
ENST00000412274.2 ENST00000507901.1 ENST00000507046.1 ENST00000437124.2 ENST00000454612.2 ENST00000396342.2 |
DDR1
|
discoidin domain receptor tyrosine kinase 1 |
| chr2_-_55277654 | 3.15 |
ENST00000337526.6
ENST00000317610.7 ENST00000357732.4 |
RTN4
|
reticulon 4 |
| chr20_+_34742650 | 3.14 |
ENST00000373945.1
ENST00000338074.2 |
EPB41L1
|
erythrocyte membrane protein band 4.1-like 1 |
| chr12_+_120933859 | 3.14 |
ENST00000242577.6
ENST00000548214.1 ENST00000392508.2 |
DYNLL1
|
dynein, light chain, LC8-type 1 |
| chr5_-_146833485 | 3.13 |
ENST00000398514.3
|
DPYSL3
|
dihydropyrimidinase-like 3 |
| chr11_+_2405833 | 3.13 |
ENST00000527343.1
ENST00000464784.2 |
CD81
|
CD81 molecule |
| chr16_+_56225248 | 3.12 |
ENST00000262493.6
|
GNAO1
|
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| chr4_+_41540160 | 3.12 |
ENST00000503057.1
ENST00000511496.1 |
LIMCH1
|
LIM and calponin homology domains 1 |
| chrX_+_54834791 | 3.11 |
ENST00000218439.4
ENST00000375058.1 ENST00000375060.1 |
MAGED2
|
melanoma antigen family D, 2 |
| chr14_-_51562745 | 3.10 |
ENST00000298355.3
|
TRIM9
|
tripartite motif containing 9 |
| chr12_+_120933904 | 3.09 |
ENST00000550178.1
ENST00000550845.1 ENST00000549989.1 ENST00000552870.1 |
DYNLL1
|
dynein, light chain, LC8-type 1 |
| chr15_+_41523335 | 3.08 |
ENST00000334660.5
|
CHP1
|
calcineurin-like EF-hand protein 1 |
| chr12_-_6484715 | 3.08 |
ENST00000228916.2
|
SCNN1A
|
sodium channel, non-voltage-gated 1 alpha subunit |
| chrX_-_1511617 | 3.06 |
ENST00000381401.5
|
SLC25A6
|
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
| chr7_+_98923505 | 3.06 |
ENST00000432884.2
ENST00000262942.5 |
ARPC1A
|
actin related protein 2/3 complex, subunit 1A, 41kDa |
| chr4_-_102268484 | 3.05 |
ENST00000394853.4
|
PPP3CA
|
protein phosphatase 3, catalytic subunit, alpha isozyme |
| chr10_+_74033672 | 3.04 |
ENST00000307365.3
|
DDIT4
|
DNA-damage-inducible transcript 4 |
| chr2_-_74601758 | 3.02 |
ENST00000407639.2
ENST00000409438.1 |
DCTN1
|
dynactin 1 |
| chr2_-_55277512 | 3.00 |
ENST00000402434.2
|
RTN4
|
reticulon 4 |
| chr6_-_33385854 | 2.99 |
ENST00000488478.1
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr11_+_75273246 | 2.98 |
ENST00000526397.1
ENST00000529643.1 ENST00000525492.1 ENST00000530284.1 ENST00000532356.1 ENST00000524558.1 |
SERPINH1
|
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| chr9_-_14314566 | 2.98 |
ENST00000397579.2
|
NFIB
|
nuclear factor I/B |
| chr12_+_6833237 | 2.98 |
ENST00000229251.3
ENST00000539735.1 ENST00000538410.1 |
COPS7A
|
COP9 signalosome subunit 7A |
| chr3_+_11034403 | 2.96 |
ENST00000287766.4
ENST00000425938.1 |
SLC6A1
|
solute carrier family 6 (neurotransmitter transporter), member 1 |
| chr2_+_198365095 | 2.94 |
ENST00000409468.1
|
HSPE1
|
heat shock 10kDa protein 1 |
| chr6_-_47277634 | 2.92 |
ENST00000296861.2
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21 |
| chr10_+_114709999 | 2.91 |
ENST00000355995.4
ENST00000545257.1 ENST00000543371.1 ENST00000536810.1 ENST00000355717.4 ENST00000538897.1 ENST00000534894.1 |
TCF7L2
|
transcription factor 7-like 2 (T-cell specific, HMG-box) |
| chrX_+_56590002 | 2.89 |
ENST00000338222.5
|
UBQLN2
|
ubiquilin 2 |
| chr12_-_115121962 | 2.87 |
ENST00000349155.2
|
TBX3
|
T-box 3 |
| chr16_-_65155833 | 2.87 |
ENST00000566827.1
ENST00000394156.3 ENST00000562998.1 |
CDH11
|
cadherin 11, type 2, OB-cadherin (osteoblast) |
| chr1_+_223889285 | 2.87 |
ENST00000433674.2
|
CAPN2
|
calpain 2, (m/II) large subunit |
| chr19_-_39330818 | 2.87 |
ENST00000594769.1
ENST00000602021.1 |
AC104534.3
|
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial |
| chr1_+_205473720 | 2.85 |
ENST00000429964.2
ENST00000506784.1 ENST00000360066.2 |
CDK18
|
cyclin-dependent kinase 18 |
| chr19_+_56152262 | 2.84 |
ENST00000325333.5
ENST00000590190.1 |
ZNF580
|
zinc finger protein 580 |
| chr1_+_77747656 | 2.84 |
ENST00000354567.2
|
AK5
|
adenylate kinase 5 |
| chr2_-_50574856 | 2.84 |
ENST00000342183.5
|
NRXN1
|
neurexin 1 |
| chr9_-_14314518 | 2.83 |
ENST00000397581.2
|
NFIB
|
nuclear factor I/B |
| chr16_+_8768422 | 2.83 |
ENST00000268251.8
ENST00000564714.1 |
ABAT
|
4-aminobutyrate aminotransferase |
| chr9_+_71789081 | 2.82 |
ENST00000377245.4
|
TJP2
|
tight junction protein 2 |
| chr14_-_21492113 | 2.80 |
ENST00000554094.1
|
NDRG2
|
NDRG family member 2 |
| chr1_-_113247543 | 2.79 |
ENST00000414971.1
ENST00000534717.1 |
RHOC
|
ras homolog family member C |
| chr4_-_102268628 | 2.79 |
ENST00000323055.6
ENST00000512215.1 ENST00000394854.3 |
PPP3CA
|
protein phosphatase 3, catalytic subunit, alpha isozyme |
| chr16_-_29910853 | 2.78 |
ENST00000308713.5
|
SEZ6L2
|
seizure related 6 homolog (mouse)-like 2 |
| chr13_-_67804445 | 2.78 |
ENST00000456367.1
ENST00000377861.3 ENST00000544246.1 |
PCDH9
|
protocadherin 9 |
| chr17_+_37026284 | 2.77 |
ENST00000433206.2
ENST00000435347.3 |
LASP1
|
LIM and SH3 protein 1 |
| chr11_-_64410787 | 2.75 |
ENST00000301894.2
|
NRXN2
|
neurexin 2 |
| chr4_-_74124502 | 2.75 |
ENST00000358602.4
ENST00000330838.6 ENST00000561029.1 |
ANKRD17
|
ankyrin repeat domain 17 |
| chr7_-_23510086 | 2.75 |
ENST00000258729.3
|
IGF2BP3
|
insulin-like growth factor 2 mRNA binding protein 3 |
| chr11_+_75273101 | 2.75 |
ENST00000533603.1
ENST00000358171.3 ENST00000526242.1 |
SERPINH1
|
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| chr5_+_125758813 | 2.75 |
ENST00000285689.3
ENST00000515200.1 |
GRAMD3
|
GRAM domain containing 3 |
| chr12_+_110719032 | 2.74 |
ENST00000395494.2
|
ATP2A2
|
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| chr5_+_173472607 | 2.74 |
ENST00000303177.3
ENST00000519867.1 |
NSG2
|
Neuron-specific protein family member 2 |
| chr3_-_168864427 | 2.73 |
ENST00000468789.1
|
MECOM
|
MDS1 and EVI1 complex locus |
| chr6_-_56819385 | 2.73 |
ENST00000370754.5
ENST00000449297.2 |
DST
|
dystonin |
| chr6_-_33385870 | 2.72 |
ENST00000488034.1
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr12_-_53893399 | 2.72 |
ENST00000267079.2
|
MAP3K12
|
mitogen-activated protein kinase kinase kinase 12 |
| chr9_+_71789133 | 2.69 |
ENST00000348208.4
ENST00000265384.7 |
TJP2
|
tight junction protein 2 |
| chr2_+_8822113 | 2.69 |
ENST00000396290.1
ENST00000331129.3 |
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| chr20_+_44035847 | 2.68 |
ENST00000372712.2
|
DBNDD2
|
dysbindin (dystrobrevin binding protein 1) domain containing 2 |
| chr2_-_47403642 | 2.68 |
ENST00000456319.1
ENST00000409563.1 ENST00000272298.7 |
CALM2
|
calmodulin 2 (phosphorylase kinase, delta) |
| chr2_-_152684977 | 2.65 |
ENST00000428992.2
ENST00000295087.8 |
ARL5A
|
ADP-ribosylation factor-like 5A |
| chr7_+_134551583 | 2.65 |
ENST00000435928.1
|
CALD1
|
caldesmon 1 |
| chr8_+_104513086 | 2.65 |
ENST00000406091.3
|
RIMS2
|
regulating synaptic membrane exocytosis 2 |
| chr6_-_33385655 | 2.65 |
ENST00000440279.3
ENST00000607266.1 |
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr20_+_57427765 | 2.63 |
ENST00000371100.4
|
GNAS
|
GNAS complex locus |
| chr3_-_134093275 | 2.63 |
ENST00000513145.1
ENST00000422605.2 |
AMOTL2
|
angiomotin like 2 |
| chr10_-_62493223 | 2.63 |
ENST00000373827.2
|
ANK3
|
ankyrin 3, node of Ranvier (ankyrin G) |
| chr5_+_125758865 | 2.62 |
ENST00000542322.1
ENST00000544396.1 |
GRAMD3
|
GRAM domain containing 3 |
| chr22_-_39639021 | 2.62 |
ENST00000455790.1
|
PDGFB
|
platelet-derived growth factor beta polypeptide |
| chr7_+_30951461 | 2.62 |
ENST00000311813.4
|
AQP1
|
aquaporin 1 (Colton blood group) |
| chr3_+_183894566 | 2.62 |
ENST00000439647.1
|
AP2M1
|
adaptor-related protein complex 2, mu 1 subunit |
| chr7_+_65552756 | 2.60 |
ENST00000450043.1
|
AC068533.7
|
AC068533.7 |
| chr12_-_16761007 | 2.58 |
ENST00000354662.1
ENST00000441439.2 |
LMO3
|
LIM domain only 3 (rhombotin-like 2) |
| chr19_-_6502590 | 2.57 |
ENST00000264071.2
|
TUBB4A
|
tubulin, beta 4A class IVa |
| chr1_+_160085501 | 2.56 |
ENST00000361216.3
|
ATP1A2
|
ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| chr11_+_62475130 | 2.54 |
ENST00000294117.5
|
GNG3
|
guanine nucleotide binding protein (G protein), gamma 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GTF2I
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.7 | 26.9 | GO:1903288 | protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288) |
| 3.5 | 10.5 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 2.9 | 8.6 | GO:1903233 | regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) |
| 2.8 | 13.8 | GO:1903275 | regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278) |
| 2.7 | 8.0 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 2.1 | 10.7 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 2.0 | 12.2 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 1.9 | 5.8 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 1.9 | 9.5 | GO:0015688 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 1.9 | 5.7 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) |
| 1.8 | 5.5 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 1.8 | 12.7 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 1.7 | 15.6 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 1.7 | 6.9 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 1.7 | 5.0 | GO:1903570 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 1.6 | 9.5 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 1.6 | 9.5 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
| 1.6 | 22.0 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 1.6 | 6.3 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 1.6 | 6.3 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 1.5 | 9.1 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 1.5 | 10.6 | GO:0021540 | corpus callosum morphogenesis(GO:0021540) |
| 1.5 | 2.9 | GO:0097252 | oligodendrocyte apoptotic process(GO:0097252) |
| 1.4 | 4.1 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 1.4 | 4.1 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 1.3 | 4.0 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 1.3 | 9.0 | GO:0021740 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 1.3 | 6.3 | GO:0003408 | optic cup formation involved in camera-type eye development(GO:0003408) |
| 1.3 | 3.8 | GO:1904647 | response to rotenone(GO:1904647) |
| 1.2 | 3.7 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 1.2 | 8.5 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 1.2 | 9.6 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 1.2 | 3.6 | GO:0052031 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) |
| 1.2 | 4.6 | GO:0010159 | specification of organ position(GO:0010159) |
| 1.2 | 1.2 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 1.2 | 4.6 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 1.1 | 29.4 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 1.1 | 3.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 1.1 | 3.2 | GO:1904529 | regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617) |
| 1.0 | 4.2 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 1.0 | 4.1 | GO:0048749 | compound eye development(GO:0048749) |
| 1.0 | 5.0 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
| 1.0 | 3.9 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
| 0.9 | 2.8 | GO:0009183 | ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) |
| 0.9 | 9.3 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.9 | 0.9 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.9 | 0.9 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.9 | 2.6 | GO:0072019 | carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) |
| 0.9 | 5.2 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.8 | 2.5 | GO:0021778 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.8 | 2.5 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.8 | 3.3 | GO:0014053 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450) |
| 0.8 | 4.1 | GO:0099551 | synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) |
| 0.8 | 0.8 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
| 0.8 | 3.1 | GO:0043126 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.8 | 3.8 | GO:0061107 | prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107) |
| 0.7 | 3.0 | GO:0014054 | positive regulation of gamma-aminobutyric acid secretion(GO:0014054) |
| 0.7 | 2.9 | GO:0003095 | pressure natriuresis(GO:0003095) |
| 0.7 | 2.9 | GO:1900186 | negative regulation of clathrin-mediated endocytosis(GO:1900186) |
| 0.7 | 7.2 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.7 | 6.4 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.7 | 4.3 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
| 0.7 | 5.6 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.7 | 2.8 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.7 | 0.7 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
| 0.7 | 2.0 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.7 | 3.4 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.7 | 4.7 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.7 | 4.7 | GO:0070445 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
| 0.7 | 2.0 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 0.7 | 2.6 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
| 0.7 | 2.0 | GO:0035989 | tendon development(GO:0035989) |
| 0.7 | 2.6 | GO:0072660 | positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.6 | 1.9 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.6 | 2.6 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
| 0.6 | 5.1 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.6 | 5.6 | GO:0021978 | telencephalon regionalization(GO:0021978) |
| 0.6 | 3.7 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.6 | 0.6 | GO:1902954 | regulation of early endosome to recycling endosome transport(GO:1902954) |
| 0.6 | 6.6 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.6 | 7.7 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.6 | 1.7 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
| 0.6 | 4.6 | GO:0003190 | atrioventricular valve formation(GO:0003190) |
| 0.6 | 1.7 | GO:0048627 | myoblast development(GO:0048627) |
| 0.6 | 6.3 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
| 0.6 | 6.2 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.6 | 0.6 | GO:1901535 | regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) |
| 0.6 | 1.7 | GO:2000612 | thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612) |
| 0.6 | 3.4 | GO:0010909 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.5 | 7.1 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 0.5 | 1.1 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.5 | 8.2 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.5 | 1.6 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.5 | 5.3 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 0.5 | 2.1 | GO:1904046 | negative regulation of vascular endothelial growth factor production(GO:1904046) |
| 0.5 | 2.6 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.5 | 2.1 | GO:0090677 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.5 | 1.0 | GO:0097327 | response to antineoplastic agent(GO:0097327) |
| 0.5 | 3.1 | GO:0045955 | negative regulation of calcium ion-dependent exocytosis(GO:0045955) |
| 0.5 | 1.5 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.5 | 3.0 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.5 | 10.6 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.5 | 0.5 | GO:0003241 | growth involved in heart morphogenesis(GO:0003241) |
| 0.5 | 0.5 | GO:0043524 | negative regulation of neuron apoptotic process(GO:0043524) |
| 0.5 | 3.8 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 0.5 | 2.8 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 0.5 | 2.8 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.5 | 1.4 | GO:0070295 | renal water absorption(GO:0070295) |
| 0.4 | 2.2 | GO:0033489 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 0.4 | 0.4 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 0.4 | 3.1 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.4 | 7.0 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.4 | 1.3 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.4 | 1.7 | GO:0010900 | negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
| 0.4 | 3.5 | GO:0070885 | positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) |
| 0.4 | 27.7 | GO:0008542 | visual learning(GO:0008542) |
| 0.4 | 1.3 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 0.4 | 1.3 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.4 | 1.3 | GO:0045586 | regulation of gamma-delta T cell differentiation(GO:0045586) |
| 0.4 | 3.4 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
| 0.4 | 3.8 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.4 | 3.4 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.4 | 2.1 | GO:1990910 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910) |
| 0.4 | 1.2 | GO:0006404 | RNA import into nucleus(GO:0006404) |
| 0.4 | 2.0 | GO:0021649 | vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.4 | 3.1 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.4 | 0.8 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.4 | 1.5 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 0.4 | 7.2 | GO:2001046 | positive regulation of integrin-mediated signaling pathway(GO:2001046) |
| 0.4 | 5.9 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.4 | 1.8 | GO:0019255 | glucose 1-phosphate metabolic process(GO:0019255) |
| 0.4 | 1.8 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.4 | 7.3 | GO:0048846 | axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284) |
| 0.4 | 1.4 | GO:0043335 | protein unfolding(GO:0043335) |
| 0.4 | 1.8 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.3 | 3.1 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.3 | 2.4 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 0.3 | 2.1 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 0.3 | 1.7 | GO:0030070 | insulin processing(GO:0030070) |
| 0.3 | 2.7 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.3 | 0.7 | GO:1900238 | positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591) |
| 0.3 | 2.0 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.3 | 6.1 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.3 | 1.0 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 0.3 | 0.7 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.3 | 3.0 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.3 | 1.0 | GO:0060022 | hard palate development(GO:0060022) |
| 0.3 | 1.9 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.3 | 2.3 | GO:0071670 | smooth muscle cell chemotaxis(GO:0071670) |
| 0.3 | 6.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.3 | 1.9 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.3 | 3.1 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.3 | 3.4 | GO:1901673 | regulation of mitotic spindle assembly(GO:1901673) |
| 0.3 | 1.5 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.3 | 1.8 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.3 | 3.5 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.3 | 6.8 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.3 | 0.9 | GO:0061188 | negative regulation of chromatin silencing at rDNA(GO:0061188) |
| 0.3 | 0.3 | GO:0021769 | orbitofrontal cortex development(GO:0021769) |
| 0.3 | 1.2 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 0.3 | 2.9 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 0.3 | 2.9 | GO:0043578 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.3 | 1.1 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.3 | 0.6 | GO:0072104 | glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) |
| 0.3 | 4.5 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.3 | 0.8 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
| 0.3 | 2.0 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.3 | 4.4 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.3 | 2.8 | GO:0009886 | post-embryonic morphogenesis(GO:0009886) |
| 0.3 | 2.5 | GO:0032471 | negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) |
| 0.3 | 1.6 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.3 | 1.3 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.3 | 2.4 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.3 | 2.7 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.3 | 1.3 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.3 | 2.1 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.3 | 2.1 | GO:0006983 | ER overload response(GO:0006983) |
| 0.3 | 4.4 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.3 | 0.8 | GO:0001554 | luteolysis(GO:0001554) |
| 0.3 | 0.8 | GO:0021612 | rhombomere 5 development(GO:0021571) facial nerve structural organization(GO:0021612) |
| 0.3 | 0.8 | GO:0035900 | response to isolation stress(GO:0035900) |
| 0.3 | 0.5 | GO:1900155 | regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155) |
| 0.3 | 1.8 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.2 | 1.9 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.2 | 2.2 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.2 | 1.0 | GO:0043489 | RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255) |
| 0.2 | 0.7 | GO:0061743 | motor learning(GO:0061743) |
| 0.2 | 1.6 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.2 | 0.5 | GO:0043254 | regulation of protein complex assembly(GO:0043254) |
| 0.2 | 0.9 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.2 | 0.9 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 0.2 | 0.2 | GO:1904037 | positive regulation of epithelial cell apoptotic process(GO:1904037) |
| 0.2 | 2.0 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.2 | 0.5 | GO:1901490 | regulation of lymphangiogenesis(GO:1901490) |
| 0.2 | 0.7 | GO:2000969 | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.2 | 0.9 | GO:1904398 | positive regulation of neuromuscular junction development(GO:1904398) |
| 0.2 | 1.8 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.2 | 7.1 | GO:1901687 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.2 | 1.1 | GO:0098903 | regulation of membrane repolarization during action potential(GO:0098903) |
| 0.2 | 7.4 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.2 | 6.4 | GO:0008104 | protein localization(GO:0008104) |
| 0.2 | 1.3 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.2 | 2.5 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 0.2 | 1.1 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.2 | 1.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.2 | 5.0 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.2 | 3.7 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.2 | 1.4 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.2 | 1.0 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.2 | 0.8 | GO:0075509 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.2 | 3.4 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.2 | 0.6 | GO:0090650 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.2 | 1.2 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.2 | 1.6 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.2 | 1.0 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.2 | 0.6 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.2 | 1.3 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.2 | 2.1 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.2 | 1.7 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
| 0.2 | 7.2 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.2 | 0.9 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.2 | 4.1 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.2 | 0.9 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.2 | 1.1 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.2 | 0.5 | GO:1903412 | response to bile acid(GO:1903412) |
| 0.2 | 1.4 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) |
| 0.2 | 0.7 | GO:0035711 | plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.2 | 0.8 | GO:0060356 | leucine import(GO:0060356) |
| 0.2 | 1.0 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.2 | 9.4 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.2 | 1.0 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.2 | 5.3 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.2 | 0.3 | GO:1904849 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.2 | 2.9 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.2 | 7.7 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.2 | 1.1 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
| 0.2 | 0.5 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.2 | 0.5 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.2 | 3.4 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.2 | 2.6 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.2 | 0.3 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.2 | 0.3 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.2 | 0.8 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.2 | 0.9 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.2 | 0.5 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.2 | 2.8 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.2 | 1.1 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.1 | 1.3 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 1.5 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.1 | 1.2 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 0.7 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.1 | 0.6 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.1 | 0.7 | GO:0010511 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) |
| 0.1 | 0.7 | GO:0061051 | positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) |
| 0.1 | 4.9 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.1 | 4.0 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.1 | 1.2 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.1 | 1.8 | GO:0007184 | SMAD protein import into nucleus(GO:0007184) |
| 0.1 | 4.6 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.1 | 3.2 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.1 | 5.2 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.1 | 2.7 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.8 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.1 | 0.4 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.1 | 3.9 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.1 | 3.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.6 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
| 0.1 | 1.7 | GO:0031103 | axon regeneration(GO:0031103) |
| 0.1 | 2.0 | GO:0015800 | acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813) |
| 0.1 | 1.1 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.1 | 0.6 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.1 | 2.3 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.1 | 0.7 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.1 | 1.1 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 0.6 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.1 | 0.7 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 0.7 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.1 | 0.8 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.1 | 1.1 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.1 | 1.6 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.1 | 0.3 | GO:0046440 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 0.1 | 0.4 | GO:0042231 | interleukin-13 biosynthetic process(GO:0042231) |
| 0.1 | 0.3 | GO:0032909 | transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909) |
| 0.1 | 2.2 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.1 | 0.4 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.1 | 1.0 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.1 | 4.3 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.1 | 0.6 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.1 | 0.3 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
| 0.1 | 0.6 | GO:0019050 | suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526) cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.1 | 1.5 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
| 0.1 | 0.4 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.1 | 1.1 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 0.7 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.1 | 0.8 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.1 | 2.3 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.1 | 1.6 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 0.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.1 | 0.3 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.1 | 1.3 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.1 | 3.2 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.1 | 1.1 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 0.9 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 0.9 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
| 0.1 | 2.8 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
| 0.1 | 0.8 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860) |
| 0.1 | 0.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.1 | 0.4 | GO:1902065 | response to L-glutamate(GO:1902065) |
| 0.1 | 5.1 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 0.5 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.1 | 1.1 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.1 | 0.7 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) regulation of glycogen (starch) synthase activity(GO:2000465) positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 2.0 | GO:0010832 | negative regulation of myotube differentiation(GO:0010832) |
| 0.1 | 1.6 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.1 | 2.1 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.1 | 0.4 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.1 | 0.9 | GO:1904261 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.1 | 0.4 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.1 | 1.0 | GO:0019915 | lipid storage(GO:0019915) |
| 0.1 | 0.3 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 1.6 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.1 | 0.5 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.1 | 0.9 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 0.1 | 2.5 | GO:0046949 | fatty-acyl-CoA biosynthetic process(GO:0046949) |
| 0.1 | 1.6 | GO:0034755 | iron ion transmembrane transport(GO:0034755) |
| 0.1 | 2.8 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.1 | 0.4 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.1 | 0.9 | GO:0003091 | renal water homeostasis(GO:0003091) |
| 0.1 | 1.6 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.1 | 0.8 | GO:0006662 | glycerol ether metabolic process(GO:0006662) |
| 0.1 | 2.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.3 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.1 | 0.3 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
| 0.1 | 0.7 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 0.7 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.1 | 0.8 | GO:1901741 | regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741) |
| 0.1 | 1.7 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 0.7 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.1 | 0.5 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.1 | 0.1 | GO:0032242 | regulation of nucleoside transport(GO:0032242) |
| 0.1 | 0.9 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.1 | 2.0 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.1 | 0.5 | GO:0032228 | regulation of synaptic transmission, GABAergic(GO:0032228) |
| 0.1 | 1.5 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
| 0.1 | 3.8 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.1 | 2.1 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.1 | 1.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 1.6 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
| 0.1 | 0.8 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.1 | 0.1 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
| 0.1 | 1.5 | GO:0002369 | T cell cytokine production(GO:0002369) |
| 0.1 | 0.6 | GO:0019724 | immunoglobulin mediated immune response(GO:0016064) B cell mediated immunity(GO:0019724) |
| 0.1 | 0.1 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) retinal blood vessel morphogenesis(GO:0061304) |
| 0.1 | 0.8 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.1 | 2.6 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 0.1 | 1.5 | GO:0060291 | long-term synaptic potentiation(GO:0060291) |
| 0.0 | 0.5 | GO:1903817 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.0 | 0.3 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.0 | 1.8 | GO:0055078 | sodium ion homeostasis(GO:0055078) |
| 0.0 | 0.4 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.0 | 0.2 | GO:0034442 | regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) |
| 0.0 | 0.4 | GO:0042993 | positive regulation of transcription factor import into nucleus(GO:0042993) |
| 0.0 | 1.2 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.8 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 0.3 | GO:0050915 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) sensory perception of sour taste(GO:0050915) |
| 0.0 | 0.6 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
| 0.0 | 0.6 | GO:0007567 | parturition(GO:0007567) |
| 0.0 | 0.3 | GO:0035924 | cellular response to vascular endothelial growth factor stimulus(GO:0035924) |
| 0.0 | 0.5 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.6 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.0 | 0.2 | GO:1903242 | regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242) |
| 0.0 | 2.0 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.0 | 1.0 | GO:0030516 | regulation of axon extension(GO:0030516) |
| 0.0 | 0.2 | GO:2000254 | regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255) |
| 0.0 | 0.2 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.0 | 2.0 | GO:2001234 | negative regulation of apoptotic signaling pathway(GO:2001234) |
| 0.0 | 0.2 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) |
| 0.0 | 1.4 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.0 | 0.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 0.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 1.0 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.0 | 1.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.2 | GO:0010994 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 0.0 | 0.3 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.0 | 2.0 | GO:0035305 | negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308) |
| 0.0 | 5.2 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 0.0 | 0.4 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.0 | 0.5 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.0 | 0.1 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) |
| 0.0 | 0.1 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.0 | 3.2 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 0.0 | 0.7 | GO:0050427 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.0 | 1.6 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 0.4 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.0 | 0.4 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.0 | 0.9 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.4 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.0 | 0.2 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.0 | 0.1 | GO:0071233 | cellular response to leucine(GO:0071233) |
| 0.0 | 1.2 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 0.0 | 0.5 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.2 | GO:0098868 | endochondral bone growth(GO:0003416) bone growth(GO:0098868) |
| 0.0 | 0.1 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.0 | 0.3 | GO:0019321 | pentose metabolic process(GO:0019321) |
| 0.0 | 0.3 | GO:0051683 | establishment of Golgi localization(GO:0051683) Golgi reassembly(GO:0090168) |
| 0.0 | 0.5 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
| 0.0 | 0.4 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.3 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.0 | 0.9 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.0 | 0.1 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
| 0.0 | 0.5 | GO:0042551 | neuron maturation(GO:0042551) |
| 0.0 | 0.2 | GO:0006633 | fatty acid biosynthetic process(GO:0006633) |
| 0.0 | 0.4 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.0 | 0.4 | GO:0002190 | cap-independent translational initiation(GO:0002190) IRES-dependent translational initiation(GO:0002192) |
| 0.0 | 0.1 | GO:0097384 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129) cellular lipid biosynthetic process(GO:0097384) |
| 0.0 | 1.1 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
| 0.0 | 0.8 | GO:0090305 | nucleic acid phosphodiester bond hydrolysis(GO:0090305) |
| 0.0 | 0.5 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.0 | 0.2 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.0 | 0.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 0.9 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.3 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.0 | 2.7 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.0 | 0.0 | GO:0048548 | regulation of pinocytosis(GO:0048548) positive regulation of pinocytosis(GO:0048549) dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) negative regulation of dendritic cell apoptotic process(GO:2000669) |
| 0.0 | 0.6 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101) |
| 0.0 | 0.6 | GO:0050710 | negative regulation of cytokine secretion(GO:0050710) |
| 0.0 | 0.0 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 0.0 | 0.4 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.3 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.0 | 0.7 | GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway(GO:2001237) |
| 0.0 | 0.8 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
| 0.0 | 0.4 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.5 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 0.7 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.0 | 0.1 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.0 | 0.0 | GO:0035646 | endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
| 0.0 | 0.2 | GO:0042953 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.0 | 0.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 1.1 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.0 | 0.6 | GO:0042035 | regulation of cytokine biosynthetic process(GO:0042035) |
| 0.0 | 0.6 | GO:0065002 | intracellular protein transmembrane transport(GO:0065002) |
| 0.0 | 0.1 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.0 | 0.2 | GO:0009411 | response to UV(GO:0009411) |
| 0.0 | 0.6 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 8.6 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 2.2 | 44.3 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 1.9 | 5.6 | GO:1990015 | mesaxon(GO:0097453) ensheathing process(GO:1990015) |
| 1.8 | 10.7 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 1.6 | 4.7 | GO:0072534 | perineuronal net(GO:0072534) |
| 1.1 | 7.7 | GO:0032584 | growth cone membrane(GO:0032584) |
| 1.0 | 20.6 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 1.0 | 13.3 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 1.0 | 3.0 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
| 1.0 | 4.9 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 1.0 | 3.8 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.9 | 7.2 | GO:0005818 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.9 | 6.3 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.9 | 4.4 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.9 | 2.6 | GO:0020003 | symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) |
| 0.8 | 8.3 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.8 | 3.3 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.7 | 9.7 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.7 | 6.2 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.7 | 2.7 | GO:0031673 | H zone(GO:0031673) |
| 0.7 | 13.3 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.7 | 6.0 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.7 | 2.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.6 | 3.2 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.6 | 0.6 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.6 | 3.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) |
| 0.5 | 6.1 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.5 | 1.0 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.5 | 0.5 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.5 | 5.6 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.4 | 3.1 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.4 | 2.6 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.4 | 4.6 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.4 | 1.5 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.4 | 5.8 | GO:0043073 | germ cell nucleus(GO:0043073) |
| 0.4 | 4.3 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.4 | 1.8 | GO:0070110 | ciliary neurotrophic factor receptor complex(GO:0070110) |
| 0.4 | 1.4 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 0.3 | 2.8 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.3 | 1.0 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.3 | 11.3 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.3 | 3.3 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.3 | 8.6 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.3 | 15.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.3 | 9.0 | GO:0030057 | desmosome(GO:0030057) |
| 0.3 | 3.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.3 | 1.8 | GO:0072487 | MSL complex(GO:0072487) |
| 0.3 | 0.8 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.3 | 2.8 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.3 | 3.1 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.3 | 1.8 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.3 | 1.0 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.2 | 1.7 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.2 | 6.3 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.2 | 3.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.2 | 1.9 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.2 | 15.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.2 | 1.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.2 | 2.9 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.2 | 4.2 | GO:0042627 | chylomicron(GO:0042627) |
| 0.2 | 4.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.2 | 2.5 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.2 | 11.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 3.0 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.2 | 0.6 | GO:0000798 | nuclear cohesin complex(GO:0000798) |
| 0.2 | 2.2 | GO:0032797 | SMN complex(GO:0032797) |
| 0.2 | 10.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.2 | 3.3 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.2 | 1.9 | GO:0043218 | compact myelin(GO:0043218) |
| 0.2 | 1.7 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.2 | 0.4 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.2 | 3.2 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.2 | 30.1 | GO:0030426 | growth cone(GO:0030426) |
| 0.2 | 0.2 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.2 | 0.7 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.2 | 2.7 | GO:0030478 | actin cap(GO:0030478) |
| 0.2 | 3.9 | GO:0034706 | sodium channel complex(GO:0034706) |
| 0.2 | 8.1 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.2 | 3.0 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.2 | 1.7 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.2 | 1.9 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.2 | 0.6 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.2 | 2.6 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.2 | 1.8 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.2 | 1.2 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.2 | 0.5 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.2 | 40.5 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.1 | 1.2 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.1 | 1.8 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.1 | 4.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.1 | 4.7 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.1 | 17.2 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 2.0 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.1 | 4.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 2.8 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 1.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 3.4 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.1 | 0.9 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 2.1 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 2.1 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 0.8 | GO:0000835 | ER ubiquitin ligase complex(GO:0000835) |
| 0.1 | 1.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 2.6 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 0.7 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.1 | 1.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 0.7 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 1.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 1.4 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.1 | 1.5 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.1 | 0.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 0.6 | GO:0098827 | endoplasmic reticulum subcompartment(GO:0098827) |
| 0.1 | 2.0 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 0.4 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.1 | 0.5 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.1 | 0.7 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.1 | 3.1 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 1.9 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 0.5 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 9.2 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.1 | 6.2 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 1.0 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 4.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 1.5 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 0.4 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.1 | 0.5 | GO:1990393 | 3M complex(GO:1990393) |
| 0.1 | 1.4 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.1 | 1.4 | GO:0000786 | nucleosome(GO:0000786) DNA packaging complex(GO:0044815) |
| 0.1 | 27.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 1.0 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.1 | 0.4 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.1 | 3.4 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 1.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 0.6 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 31.6 | GO:0031252 | cell leading edge(GO:0031252) |
| 0.1 | 0.9 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 2.1 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 1.1 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.1 | 32.7 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.1 | 5.1 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 0.4 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.1 | 0.8 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.1 | 0.4 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.1 | 22.9 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.1 | 0.7 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.1 | 1.4 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.1 | 0.8 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.1 | 0.8 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.1 | 4.8 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 0.2 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 0.7 | GO:0044754 | autolysosome(GO:0044754) |
| 0.1 | 0.7 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
| 0.1 | 1.4 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.1 | 0.9 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 13.3 | GO:0031301 | integral component of organelle membrane(GO:0031301) |
| 0.1 | 0.2 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.1 | 1.4 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 0.4 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.1 | 0.8 | GO:1990752 | microtubule end(GO:1990752) |
| 0.1 | 0.6 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.1 | 0.7 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 1.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.4 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 0.3 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.3 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.0 | 0.1 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.0 | 1.9 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 3.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.4 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.5 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 2.7 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 5.1 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 0.2 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.0 | 0.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.8 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 1.2 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.0 | 2.2 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 3.3 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.0 | 3.5 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 12.1 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 0.4 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.0 | 2.8 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 1.0 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 2.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.5 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
| 0.0 | 16.4 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 2.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.7 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.2 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
| 0.0 | 0.1 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.0 | 0.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 1.0 | GO:1990904 | intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904) |
| 0.0 | 2.0 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.2 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.0 | 1.7 | GO:0005840 | ribosome(GO:0005840) |
| 0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 5.3 | GO:0019866 | organelle inner membrane(GO:0019866) |
| 0.0 | 5.2 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.3 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.6 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.3 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.0 | 0.3 | GO:0019867 | mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968) |
| 0.0 | 1.0 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 0.1 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.6 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.1 | GO:0031527 | filopodium membrane(GO:0031527) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 8.6 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 2.6 | 7.7 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 2.5 | 27.3 | GO:0030274 | LIM domain binding(GO:0030274) |
| 2.0 | 10.1 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 1.8 | 29.0 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 1.8 | 7.2 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 1.8 | 10.7 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 1.5 | 4.6 | GO:0003881 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881) |
| 1.4 | 5.6 | GO:0005471 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 1.3 | 7.7 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 1.2 | 15.4 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 1.0 | 5.0 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 1.0 | 3.9 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
| 0.9 | 5.6 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.9 | 5.6 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.9 | 0.9 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.9 | 2.6 | GO:0035379 | carbon dioxide transmembrane transporter activity(GO:0035379) |
| 0.9 | 3.4 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.8 | 3.3 | GO:0003867 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.8 | 5.0 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.8 | 6.6 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.8 | 2.5 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.8 | 4.1 | GO:0060175 | brain-derived neurotrophic factor-activated receptor activity(GO:0060175) |
| 0.8 | 4.9 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.8 | 4.9 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.8 | 3.2 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
| 0.8 | 7.7 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.8 | 10.6 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.7 | 5.9 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.7 | 2.9 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
| 0.7 | 13.1 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.7 | 5.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.7 | 2.1 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.7 | 13.3 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.6 | 3.2 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.6 | 1.8 | GO:0051748 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 0.6 | 3.7 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.6 | 1.7 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 0.6 | 3.9 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.6 | 3.4 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.6 | 2.8 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 0.5 | 1.6 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.5 | 1.6 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.5 | 3.1 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.5 | 2.0 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.5 | 4.0 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.5 | 3.0 | GO:0015185 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 0.5 | 1.9 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.4 | 2.2 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 0.4 | 4.7 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.4 | 2.0 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.4 | 2.0 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.4 | 2.8 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.4 | 5.3 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.4 | 5.7 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.4 | 1.5 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 0.4 | 7.8 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.4 | 1.8 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.4 | 4.8 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.4 | 3.6 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.4 | 1.8 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.3 | 1.0 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
| 0.3 | 4.1 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.3 | 1.0 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.3 | 1.0 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.3 | 3.9 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.3 | 1.9 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.3 | 3.9 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.3 | 1.3 | GO:0035473 | lipase binding(GO:0035473) |
| 0.3 | 3.2 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.3 | 8.7 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.3 | 1.5 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.3 | 2.7 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.3 | 1.8 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.3 | 4.1 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.3 | 7.0 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.3 | 1.2 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 0.3 | 22.4 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.3 | 0.8 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
| 0.3 | 13.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.3 | 3.6 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.3 | 14.6 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.3 | 3.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.3 | 5.3 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.3 | 6.6 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.3 | 1.6 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.3 | 0.8 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.3 | 0.8 | GO:0048030 | disaccharide binding(GO:0048030) |
| 0.3 | 0.8 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.3 | 1.3 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.2 | 2.5 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.2 | 1.7 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.2 | 1.0 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.2 | 3.9 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.2 | 4.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.2 | 1.7 | GO:0004996 | thyroid-stimulating hormone receptor activity(GO:0004996) |
| 0.2 | 1.2 | GO:0005534 | galactose binding(GO:0005534) |
| 0.2 | 1.6 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.2 | 0.7 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.2 | 1.1 | GO:0038051 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.2 | 0.7 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.2 | 5.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.2 | 7.6 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.2 | 2.6 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.2 | 1.3 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.2 | 3.2 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.2 | 3.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.2 | 1.4 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.2 | 0.8 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.2 | 2.2 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.2 | 0.6 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.2 | 1.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.2 | 4.3 | GO:0043236 | laminin binding(GO:0043236) |
| 0.2 | 0.8 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.2 | 1.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 1.9 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.2 | 1.0 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.2 | 2.4 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.2 | 1.1 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.2 | 1.9 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.2 | 4.0 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 1.0 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 3.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.2 | 1.2 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.2 | 1.5 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.2 | 3.5 | GO:0005072 | transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) |
| 0.2 | 2.1 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.2 | 7.4 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.2 | 4.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 0.2 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.2 | 0.9 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.2 | 2.0 | GO:0031005 | filamin binding(GO:0031005) |
| 0.2 | 0.9 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.2 | 1.1 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.2 | 0.9 | GO:0043532 | angiostatin binding(GO:0043532) |
| 0.2 | 1.2 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.2 | 2.0 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 7.5 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.1 | 0.7 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.1 | 1.0 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 1.0 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.1 | 3.8 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 0.8 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.1 | 3.0 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 0.7 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 3.4 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 0.4 | GO:0086078 | gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079) |
| 0.1 | 0.5 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.1 | 1.1 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.1 | 1.3 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 8.7 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.1 | 2.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 1.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 2.1 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 0.5 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.1 | 2.5 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.4 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 0.1 | 0.9 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 1.5 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 2.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.1 | 4.1 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 3.4 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.6 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.7 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.1 | 1.4 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.1 | 0.4 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.1 | 34.5 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 0.7 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.6 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.1 | 0.9 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.1 | 4.0 | GO:1990939 | ATP-dependent microtubule motor activity(GO:1990939) |
| 0.1 | 3.5 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 1.0 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.1 | 0.8 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.1 | 2.3 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 3.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.1 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.1 | 1.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 1.5 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 0.4 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.1 | 2.7 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.1 | 0.4 | GO:0016900 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.1 | 0.7 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 10.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 4.3 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 0.4 | GO:0016823 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.1 | 2.5 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.1 | 5.1 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 0.4 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.1 | 1.5 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.1 | 2.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.1 | 2.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 0.8 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.1 | 3.7 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 1.3 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.1 | 1.2 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.1 | 1.1 | GO:0031386 | protein tag(GO:0031386) |
| 0.1 | 0.9 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 0.4 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.1 | 0.9 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 1.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 1.0 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 0.4 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 0.1 | 4.4 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.1 | 0.4 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.1 | 1.6 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 3.6 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 2.2 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 29.4 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 0.3 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.1 | 2.2 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 0.1 | 0.7 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 1.6 | GO:0042171 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.1 | 0.4 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.1 | 2.0 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 0.8 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 0.5 | GO:0001071 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.1 | 0.3 | GO:0045118 | azole transporter activity(GO:0045118) |
| 0.1 | 1.0 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 1.1 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 1.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 0.9 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.1 | 0.1 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.1 | 1.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.5 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 0.9 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 1.7 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 0.5 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.1 | 0.3 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.1 | 0.5 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.1 | 0.2 | GO:0004958 | prostaglandin F receptor activity(GO:0004958) |
| 0.0 | 0.4 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 3.7 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 5.3 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.1 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.0 | 2.6 | GO:0016879 | ligase activity, forming carbon-nitrogen bonds(GO:0016879) |
| 0.0 | 0.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 1.6 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.8 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
| 0.0 | 0.4 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.0 | 0.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.1 | GO:0001224 | RNA polymerase II transcription cofactor binding(GO:0001224) |
| 0.0 | 0.9 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.5 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.0 | 4.9 | GO:0020037 | heme binding(GO:0020037) |
| 0.0 | 3.0 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.2 | GO:0015172 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.0 | 0.7 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.0 | 0.8 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.0 | 0.2 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.0 | 0.5 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 0.7 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.6 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 20.8 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 0.4 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 1.5 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.2 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 0.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 1.0 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.4 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.0 | 0.6 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 1.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 8.3 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.2 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 0.0 | 3.2 | GO:0008514 | organic anion transmembrane transporter activity(GO:0008514) |
| 0.0 | 0.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 1.6 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 12.0 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 4.6 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.1 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 0.0 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.0 | 0.3 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.1 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.0 | 0.4 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 0.1 | GO:0043199 | sulfate binding(GO:0043199) |
| 0.0 | 0.2 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 1.1 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.4 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.1 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.2 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 0.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.8 | GO:0005319 | lipid transporter activity(GO:0005319) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 25.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.4 | 7.4 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.4 | 39.2 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.4 | 0.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.3 | 4.4 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.3 | 10.0 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.3 | 6.1 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.2 | 9.1 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.2 | 1.6 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 13.6 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.2 | 16.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.2 | 1.7 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.2 | 7.9 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.2 | 5.8 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.2 | 34.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.2 | 2.3 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.2 | 6.5 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 6.9 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 3.2 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 0.7 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 5.5 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 5.6 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 1.0 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 3.1 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 1.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 2.2 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.5 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 4.2 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.1 | 3.2 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 4.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 1.0 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.1 | 1.4 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 3.9 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 5.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 3.4 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.1 | 1.5 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 2.9 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 0.7 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.1 | 1.3 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.1 | 4.5 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 8.1 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 1.6 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.1 | 3.4 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.1 | 0.4 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 2.9 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 1.1 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.1 | 4.5 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.6 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 1.0 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.0 | 4.3 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 3.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 1.2 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 0.5 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 1.4 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 2.0 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.4 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 0.6 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.7 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.6 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.6 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 0.3 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.5 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 0.3 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 0.3 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.2 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 0.2 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 37.3 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.7 | 9.7 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.6 | 17.7 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.6 | 10.1 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.6 | 6.9 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.6 | 3.7 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.5 | 17.2 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.5 | 13.3 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.4 | 8.2 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.4 | 11.2 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.4 | 9.4 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.4 | 12.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.4 | 10.8 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.3 | 6.2 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.3 | 5.6 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.3 | 4.7 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.3 | 6.2 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.3 | 9.3 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.3 | 11.8 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.3 | 5.0 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.3 | 3.2 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.3 | 7.2 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.2 | 3.7 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.2 | 8.1 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.2 | 3.3 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 23.9 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.2 | 7.7 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.2 | 7.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 4.2 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.2 | 2.0 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.2 | 1.8 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.2 | 2.6 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.2 | 2.2 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.2 | 3.4 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.2 | 7.0 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 10.1 | REACTOME REGULATION OF INSULIN SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.2 | 5.2 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.2 | 6.2 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.2 | 1.2 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.1 | 5.9 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 0.1 | 2.6 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 10.7 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 2.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 10.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 1.0 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.1 | 7.1 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 5.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 1.8 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 4.3 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 2.3 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 3.2 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 1.9 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 2.1 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 1.3 | REACTOME CTLA4 INHIBITORY SIGNALING | Genes involved in CTLA4 inhibitory signaling |
| 0.1 | 1.2 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.1 | 3.4 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 1.8 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 1.4 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 1.6 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.1 | 8.3 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.1 | 0.3 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 2.6 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 1.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 10.3 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 2.1 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 6.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 7.2 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.1 | 1.3 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 0.9 | REACTOME AQUAPORIN MEDIATED TRANSPORT | Genes involved in Aquaporin-mediated transport |
| 0.1 | 7.0 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 1.1 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 3.6 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 2.2 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 0.9 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.8 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.7 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.7 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 1.1 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.1 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 2.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 1.0 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 0.7 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.0 | 0.5 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 1.2 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.7 | REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM | Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism |
| 0.0 | 0.6 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 7.4 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 1.0 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.6 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 0.7 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.4 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 0.0 | 0.7 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.7 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.6 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 1.5 | REACTOME S PHASE | Genes involved in S Phase |
| 0.0 | 0.6 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 0.5 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.3 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.2 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |