Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for GUAACAG
Z-value: 0.73
Motif logo
miRNA associated with seed GUAACAG
| Name | miRBASE accession |
|---|---|
|
hsa-miR-194-5p
|
MIMAT0000460 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_62658186 Show fit | 8.13 |
ENST00000262435.9
|
SMAD specific E3 ubiquitin protein ligase 2 |
|
| chr20_-_43977055 Show fit | 6.24 |
ENST00000372733.3
ENST00000537976.1 |
syndecan 4 |
|
| chrX_+_119737806 Show fit | 5.89 |
ENST00000371317.5
|
malignant T cell amplified sequence 1 |
|
| chr1_-_225840747 Show fit | 5.70 |
ENST00000366843.2
ENST00000366844.3 |
enabled homolog (Drosophila) |
|
| chr7_-_94285511 Show fit | 5.42 |
ENST00000265735.7
|
sarcoglycan, epsilon |
|
| chr9_+_131445928 Show fit | 5.37 |
ENST00000372692.4
|
SET nuclear oncogene |
|
| chr3_+_180630090 Show fit | 5.32 |
ENST00000357559.4
ENST00000305586.7 |
fragile X mental retardation, autosomal homolog 1 |
|
| chr3_-_149688896 Show fit | 5.24 |
ENST00000239940.7
|
profilin 2 |
|
| chr11_+_74660278 Show fit | 5.12 |
ENST00000263672.6
ENST00000530257.1 ENST00000526361.1 ENST00000532972.1 |
signal peptidase complex subunit 2 homolog (S. cerevisiae) |
|
| chr17_-_57784755 Show fit | 4.80 |
ENST00000537860.1
ENST00000393038.2 ENST00000409433.2 |
peptidyl-tRNA hydrolase 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GUAACAG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.3 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 2.0 | 8.1 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 2.0 | 8.0 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 1.2 | 6.2 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 2.0 | 5.9 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.0 | 5.6 | GO:0006457 | protein folding(GO:0006457) |
| 0.2 | 5.4 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.2 | 5.3 | GO:0060148 | positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637) |
| 0.1 | 5.3 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.4 | 5.2 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 11.1 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 7.8 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.1 | 5.9 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.7 | 5.4 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.1 | 5.4 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 5.3 | GO:0030175 | filopodium(GO:0030175) |
| 0.7 | 5.1 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.3 | 4.3 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.0 | 4.1 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.2 | 4.0 | GO:0031588 | cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.1 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.6 | 6.2 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 0.1 | 5.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 5.9 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 5.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 5.4 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.5 | 5.3 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) RNA strand annealing activity(GO:0033592) |
| 0.2 | 5.2 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 5.2 | GO:0003785 | actin monomer binding(GO:0003785) |
| 1.6 | 4.8 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.9 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 7.8 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 7.0 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 6.7 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 6.5 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 5.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 4.4 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 4.1 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 4.0 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 3.3 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 11.7 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.2 | 7.0 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 6.3 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 6.2 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 5.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.3 | 5.1 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.2 | 4.3 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.2 | 4.3 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 4.0 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.2 | 3.8 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |