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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for GUGCAAA

Z-value: 0.09

Motif logo

miRNA associated with seed GUGCAAA

NamemiRBASE accession
MIMAT0000073
MIMAT0000074

Activity profile of GUGCAAA motif

Sorted Z-values of GUGCAAA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_136834982 24.98 ENST00000510689.1
ENST00000394945.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr14_-_60097297 21.06 ENST00000395090.1
reticulon 1
chr1_+_51701924 20.51 ENST00000242719.3
ring finger protein 11
chr15_-_73925651 20.19 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
neuroplastin
chr6_+_121756809 18.52 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chr12_+_79258547 18.46 ENST00000457153.2
synaptotagmin I
chrX_+_135067576 16.81 ENST00000370701.1
ENST00000370698.3
ENST00000370695.4
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
chr7_-_95064264 16.75 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
paraoxonase 2
chr14_+_90863327 15.71 ENST00000356978.4
calmodulin 1 (phosphorylase kinase, delta)
chr1_+_84543734 15.52 ENST00000370689.2
protein kinase, cAMP-dependent, catalytic, beta
chr10_-_118764862 14.97 ENST00000260777.10
KIAA1598
chr5_-_73937244 12.79 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr20_+_19867150 12.78 ENST00000255006.6
Ras and Rab interactor 2
chr16_-_66785699 12.41 ENST00000258198.2
dynein, cytoplasmic 1, light intermediate chain 2
chr1_+_10271674 12.23 ENST00000377086.1
kinesin family member 1B
chr20_-_36156125 12.20 ENST00000397135.1
ENST00000397137.1
bladder cancer associated protein
chr15_-_34394119 12.08 ENST00000256545.4
ER membrane protein complex subunit 7
chr8_+_132916318 12.05 ENST00000254624.5
ENST00000522709.1
EFR3 homolog A (S. cerevisiae)
chr15_-_52861394 11.91 ENST00000563277.1
ENST00000566423.1
cAMP-regulated phosphoprotein, 19kDa
chr22_-_36236265 11.88 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_+_35840542 11.66 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
septin 7
chr1_+_236558694 11.52 ENST00000359362.5
EDAR-associated death domain
chr11_-_12030629 11.38 ENST00000396505.2
dickkopf WNT signaling pathway inhibitor 3
chr5_+_71403061 11.13 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr6_-_134639180 10.06 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr9_-_93405352 9.95 ENST00000375765.3
DIRAS family, GTP-binding RAS-like 2
chr6_-_16761678 9.80 ENST00000244769.4
ENST00000436367.1
ataxin 1
chr8_-_110660999 9.74 ENST00000424158.2
ENST00000533895.1
ENST00000446070.2
ENST00000528331.1
ENST00000526302.1
ENST00000433638.1
ENST00000408908.2
ENST00000524720.1
syntabulin (syntaxin-interacting)
chr17_-_1083078 9.51 ENST00000574266.1
ENST00000302538.5
active BCR-related
chr1_-_93426998 9.41 ENST00000370310.4
family with sequence similarity 69, member A
chr1_+_244214577 9.14 ENST00000358704.4
zinc finger and BTB domain containing 18
chr2_-_2334888 9.04 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr10_-_75173785 8.83 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
annexin A7
chr17_+_57784826 8.66 ENST00000262291.4
vacuole membrane protein 1
chr4_+_41362796 8.63 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIM and calponin homology domains 1
chr12_+_56367697 8.58 ENST00000553116.1
ENST00000360299.5
ENST00000548068.1
ENST00000549915.1
ENST00000551459.1
ENST00000448789.2
RAB5B, member RAS oncogene family
chr2_-_86094764 8.57 ENST00000393808.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_+_20646824 8.52 ENST00000272233.4
ras homolog family member B
chr17_-_62658186 8.36 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr5_+_86564739 8.25 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RAS p21 protein activator (GTPase activating protein) 1
chr1_-_1624083 8.14 ENST00000378662.1
ENST00000234800.6
solute carrier family 35, member E2B
chr2_-_169104651 8.11 ENST00000355999.4
serine threonine kinase 39
chr13_-_30424821 7.94 ENST00000380680.4
ubiquitin-like 3
chr18_+_8717369 7.92 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA family member 2
chr5_+_140227048 7.75 ENST00000532602.1
protocadherin alpha 9
chr11_-_117186946 7.68 ENST00000313005.6
ENST00000528053.1
beta-site APP-cleaving enzyme 1
chr5_+_140220769 7.63 ENST00000531613.1
ENST00000378123.3
protocadherin alpha 8
chr15_-_49338748 7.57 ENST00000559471.1
SECIS binding protein 2-like
chr1_+_155829286 7.57 ENST00000368324.4
synaptotagmin XI
chr20_-_48330377 7.56 ENST00000371711.4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr15_+_52311398 7.52 ENST00000261845.5
mitogen-activated protein kinase 6
chr11_+_121322832 7.48 ENST00000260197.7
sortilin-related receptor, L(DLR class) A repeats containing
chr8_-_103876965 7.42 ENST00000337198.5
antizyme inhibitor 1
chr14_-_64010046 7.38 ENST00000337537.3
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr2_-_225811747 7.31 ENST00000409592.3
dedicator of cytokinesis 10
chr3_-_66551351 7.25 ENST00000273261.3
leucine-rich repeats and immunoglobulin-like domains 1
chr15_-_51914996 7.08 ENST00000251076.5
Dmx-like 2
chr6_-_53213780 6.96 ENST00000304434.6
ENST00000370918.4
ELOVL fatty acid elongase 5
chr18_-_61089665 6.91 ENST00000238497.5
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr5_+_140248518 6.86 ENST00000398640.2
protocadherin alpha 11
chr3_+_130569429 6.71 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr1_+_160175117 6.67 ENST00000360472.4
phosphoprotein enriched in astrocytes 15
chr1_-_244615425 6.66 ENST00000366535.3
adenylosuccinate synthase
chr2_-_85555385 6.44 ENST00000377386.3
trans-golgi network protein 2
chr9_+_115913222 6.36 ENST00000259392.3
solute carrier family 31 (copper transporter), member 2
chr10_+_63661053 6.32 ENST00000279873.7
AT rich interactive domain 5B (MRF1-like)
chr5_+_95997918 6.30 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
calpastatin
chr1_-_51984908 6.27 ENST00000371730.2
epidermal growth factor receptor pathway substrate 15
chr2_+_9346892 6.24 ENST00000281419.3
ENST00000315273.4
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr2_+_231577532 6.23 ENST00000258418.5
calcium binding protein 39
chr1_-_70671216 6.19 ENST00000370952.3
leucine rich repeat containing 40
chrX_+_77359671 6.19 ENST00000373316.4
phosphoglycerate kinase 1
chr5_+_140306478 6.16 ENST00000253807.2
protocadherin alpha subfamily C, 1
chr16_-_47007545 6.14 ENST00000317089.5
DnaJ (Hsp40) homolog, subfamily A, member 2
chr15_+_59279851 6.09 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
ring finger protein 111
chr12_+_72148614 6.05 ENST00000261263.3
RAB21, member RAS oncogene family
chr10_-_73611046 6.03 ENST00000394934.1
ENST00000394936.3
prosaposin
chr16_-_46723066 5.99 ENST00000299138.7
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr7_-_111846435 5.97 ENST00000437633.1
ENST00000428084.1
dedicator of cytokinesis 4
chr1_-_149889382 5.97 ENST00000369145.1
ENST00000369146.3
synaptic vesicle glycoprotein 2A
chr4_-_76598296 5.94 ENST00000395719.3
GTPase activating protein (SH3 domain) binding protein 2
chr4_-_71705590 5.85 ENST00000254799.6
G-rich RNA sequence binding factor 1
chr17_-_73851285 5.82 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WW domain binding protein 2
chrX_+_118708493 5.75 ENST00000371558.2
ubiquitin-conjugating enzyme E2A
chr11_-_45687128 5.56 ENST00000308064.2
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr1_-_226924980 5.50 ENST00000272117.3
inositol-trisphosphate 3-kinase B
chr5_+_140345820 5.48 ENST00000289269.5
protocadherin alpha subfamily C, 2
chr3_-_9291063 5.48 ENST00000383836.3
SLIT-ROBO Rho GTPase activating protein 3
chr17_-_80606304 5.45 ENST00000392325.4
WD repeat domain 45B
chr17_+_57697216 5.38 ENST00000393043.1
ENST00000269122.3
clathrin, heavy chain (Hc)
chr4_-_5894777 5.34 ENST00000324989.7
collapsin response mediator protein 1
chr20_+_1246908 5.34 ENST00000381873.3
ENST00000381867.1
syntaphilin
chrX_+_146993449 5.33 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
fragile X mental retardation 1
chrX_-_34675391 5.20 ENST00000275954.3
transmembrane protein 47
chr1_-_243418344 5.13 ENST00000366542.1
centrosomal protein 170kDa
chr19_+_41768401 5.02 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr5_+_140254884 5.02 ENST00000398631.2
protocadherin alpha 12
chr15_+_40532058 4.96 ENST00000260404.4
p21 protein (Cdc42/Rac)-activated kinase 6
chr10_+_180987 4.89 ENST00000381591.1
zinc finger, MYND-type containing 11
chr1_-_212004090 4.86 ENST00000366997.4
lysophosphatidylglycerol acyltransferase 1
chr1_-_185286461 4.81 ENST00000367498.3
influenza virus NS1A binding protein
chr22_-_39268308 4.76 ENST00000407418.3
chromobox homolog 6
chr1_+_29063271 4.76 ENST00000373812.3
YTH domain family, member 2
chr12_-_57082060 4.58 ENST00000448157.2
ENST00000414274.3
ENST00000262033.6
ENST00000456859.2
prostaglandin E synthase 3 (cytosolic)
chr1_+_7831323 4.55 ENST00000054666.6
vesicle-associated membrane protein 3
chr4_+_166248775 4.54 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
methylsterol monooxygenase 1
chr5_+_140213815 4.53 ENST00000525929.1
ENST00000378125.3
protocadherin alpha 7
chr2_+_134877740 4.51 ENST00000409645.1
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr18_+_9913977 4.51 ENST00000400000.2
ENST00000340541.4
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr5_+_138940742 4.49 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
ubiquitin-conjugating enzyme E2D 2
chr6_+_96463840 4.43 ENST00000302103.5
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr3_+_50712672 4.38 ENST00000266037.9
dedicator of cytokinesis 3
chr4_-_69215699 4.33 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTH domain containing 1
chr13_+_97874574 4.31 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
muscleblind-like splicing regulator 2
chr2_-_183903133 4.31 ENST00000361354.4
NCK-associated protein 1
chr7_+_12250886 4.30 ENST00000444443.1
ENST00000396667.3
transmembrane protein 106B
chr12_+_56473628 4.28 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr10_+_111767720 4.24 ENST00000356080.4
ENST00000277900.8
adducin 3 (gamma)
chr9_-_14314066 4.23 ENST00000397575.3
nuclear factor I/B
chr3_+_49591881 4.22 ENST00000296452.4
bassoon presynaptic cytomatrix protein
chr1_+_160085501 4.21 ENST00000361216.3
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr6_-_132272504 4.20 ENST00000367976.3
connective tissue growth factor
chr20_+_47662805 4.18 ENST00000262982.2
ENST00000542325.1
CSE1 chromosome segregation 1-like (yeast)
chr22_-_21213029 4.17 ENST00000572273.1
ENST00000255882.6
phosphatidylinositol 4-kinase, catalytic, alpha
chr5_-_176889381 4.16 ENST00000393563.4
ENST00000512501.1
drebrin 1
chr17_+_57642886 4.12 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr4_+_38869410 4.08 ENST00000358869.2
family with sequence similarity 114, member A1
chr10_-_98346801 4.05 ENST00000371142.4
transmembrane 9 superfamily member 3
chr3_+_186501336 4.03 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
eukaryotic translation initiation factor 4A2
chr9_-_36400213 4.02 ENST00000259605.6
ENST00000353739.4
ring finger protein 38
chr5_+_140165876 4.01 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
protocadherin alpha 1
chr10_+_95256356 3.99 ENST00000371485.3
centrosomal protein 55kDa
chr3_-_12705600 3.92 ENST00000542177.1
ENST00000442415.2
ENST00000251849.4
v-raf-1 murine leukemia viral oncogene homolog 1
chr16_+_3070313 3.84 ENST00000326577.4
tumor necrosis factor receptor superfamily, member 12A
chr7_-_79082867 3.83 ENST00000419488.1
ENST00000354212.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_202316260 3.82 ENST00000332624.3
trafficking protein, kinesin binding 2
chr7_-_45960850 3.81 ENST00000381083.4
ENST00000381086.5
ENST00000275521.6
insulin-like growth factor binding protein 3
chr10_-_79686284 3.81 ENST00000372391.2
ENST00000372388.2
discs, large homolog 5 (Drosophila)
chr3_+_171758344 3.80 ENST00000336824.4
ENST00000423424.1
fibronectin type III domain containing 3B
chr12_-_57824739 3.78 ENST00000347140.3
ENST00000402412.1
R3H domain containing 2
chr8_+_59323823 3.76 ENST00000399598.2
UBX domain protein 2B
chr20_-_43150601 3.73 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr8_+_6565854 3.69 ENST00000285518.6
1-acylglycerol-3-phosphate O-acyltransferase 5
chr1_-_78225482 3.67 ENST00000524778.1
ENST00000370794.3
ENST00000370793.1
ENST00000370792.3
ubiquitin specific peptidase 33
chr11_+_123396528 3.61 ENST00000322282.7
ENST00000529750.1
GRAM domain containing 1B
chr8_+_104311059 3.60 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
frizzled family receptor 6
chr5_-_132073210 3.55 ENST00000378735.1
ENST00000378746.4
kinesin family member 3A
chrX_-_10645773 3.54 ENST00000453318.2
midline 1 (Opitz/BBB syndrome)
chr1_+_112162381 3.53 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A, member of RAS oncogene family
chr5_-_171433819 3.48 ENST00000296933.6
F-box and WD repeat domain containing 11
chr13_-_107187462 3.46 ENST00000245323.4
ephrin-B2
chrX_-_108976521 3.42 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
acyl-CoA synthetase long-chain family member 4
chr9_-_79520989 3.41 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
prune homolog 2 (Drosophila)
chrX_-_1511617 3.37 ENST00000381401.5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr9_+_2015335 3.31 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr20_+_19193269 3.30 ENST00000328041.6
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr16_-_46655538 3.28 ENST00000303383.3
SHC SH2-domain binding protein 1
chr8_-_67525473 3.27 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr13_-_36920420 3.25 ENST00000438666.2
spastic paraplegia 20 (Troyer syndrome)
chr5_-_133968529 3.24 ENST00000402673.2
SAR1 homolog B (S. cerevisiae)
chr2_-_161350305 3.21 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr2_-_65357225 3.19 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A, member RAS oncogene family
chr6_+_44238203 3.16 ENST00000451188.2
transmembrane protein 151B
chr17_+_68165657 3.14 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr1_+_93913713 3.09 ENST00000604705.1
ENST00000370253.2
formin binding protein 1-like
chr8_+_104831472 3.09 ENST00000262231.10
ENST00000507740.1
regulating synaptic membrane exocytosis 2
chr9_+_125703282 3.07 ENST00000373647.4
ENST00000402311.1
RAB GTPase activating protein 1
chr12_+_69004619 3.06 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B, member of RAS oncogene family
chr12_+_1800179 3.04 ENST00000357103.4
adiponectin receptor 2
chr2_+_62932779 3.01 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EH domain binding protein 1
chr10_+_96162242 3.00 ENST00000225235.4
TBC1 domain family, member 12
chr1_-_201438282 2.99 ENST00000367311.3
ENST00000367309.1
pleckstrin homology-like domain, family A, member 3
chr8_+_20054878 2.97 ENST00000276390.2
ENST00000519667.1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr1_+_178995021 2.84 ENST00000263733.4
family with sequence similarity 20, member B
chr15_+_62853562 2.84 ENST00000561311.1
talin 2
chr2_-_97535708 2.83 ENST00000305476.5
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr1_+_28099683 2.81 ENST00000373943.4
syntaxin 12
chr6_+_64281906 2.77 ENST00000370651.3
protein tyrosine phosphatase type IVA, member 1
chr17_+_16593539 2.75 ENST00000340621.5
ENST00000399273.1
ENST00000443444.2
ENST00000360524.8
ENST00000456009.1
coiled-coil domain containing 144A
chr2_-_39664405 2.73 ENST00000341681.5
ENST00000263881.3
mitogen-activated protein kinase kinase kinase kinase 3
chr12_-_53893399 2.72 ENST00000267079.2
mitogen-activated protein kinase kinase kinase 12
chr1_+_114472222 2.72 ENST00000369558.1
ENST00000369561.4
homeodomain interacting protein kinase 1
chr4_-_36246060 2.68 ENST00000303965.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_+_28966271 2.67 ENST00000375533.3
BMP and activin membrane-bound inhibitor
chr9_+_131873591 2.66 ENST00000393370.2
ENST00000337738.1
ENST00000348141.5
protein phosphatase 2A activator, regulatory subunit 4
chr1_-_222885770 2.64 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr2_+_189156389 2.63 ENST00000409843.1
GULP, engulfment adaptor PTB domain containing 1
chr9_+_103790991 2.60 ENST00000374874.3
Lipid phosphate phosphatase-related protein type 1
chr17_+_28705921 2.59 ENST00000225719.4
carboxypeptidase D
chr16_+_67063036 2.58 ENST00000290858.6
ENST00000564034.1
core-binding factor, beta subunit
chr3_-_138553594 2.58 ENST00000477593.1
ENST00000483968.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr2_-_86564776 2.57 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr4_-_170924888 2.56 ENST00000502832.1
ENST00000393704.3
microfibrillar-associated protein 3-like
chr11_+_34073195 2.56 ENST00000341394.4
cell cycle associated protein 1
chr9_-_74980113 2.53 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
zinc finger, AN1-type domain 5
chr2_-_69614373 2.52 ENST00000361060.5
ENST00000357308.4
glutamine--fructose-6-phosphate transaminase 1
chr22_-_18507279 2.52 ENST00000441493.2
ENST00000444520.1
ENST00000207726.7
ENST00000429452.1
microtubule associated monooxygenase, calponin and LIM domain containing 3
chrX_-_47479246 2.52 ENST00000295987.7
ENST00000340666.4
synapsin I
chr8_-_22550815 2.51 ENST00000317216.2
early growth response 3
chr12_+_12764773 2.50 ENST00000228865.2
cAMP responsive element binding protein-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of GUGCAAA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.6 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
6.2 18.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
4.8 14.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
4.6 18.5 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
4.1 12.2 GO:1904647 response to rotenone(GO:1904647)
3.2 9.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
3.1 15.5 GO:0097338 response to clozapine(GO:0097338)
2.8 11.4 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
2.5 7.6 GO:1905154 negative regulation of membrane invagination(GO:1905154)
2.5 7.5 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
2.5 7.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
2.4 7.3 GO:0032474 otolith morphogenesis(GO:0032474)
2.3 11.7 GO:0016476 regulation of embryonic cell shape(GO:0016476)
2.3 6.9 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
2.2 6.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
2.1 8.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.1 4.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
2.0 11.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.9 19.1 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
1.9 7.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
1.8 5.3 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
1.8 8.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.5 4.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
1.4 10.1 GO:0070294 renal sodium ion absorption(GO:0070294)
1.4 12.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.4 4.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.3 3.8 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
1.3 1.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
1.2 7.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.2 8.1 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
1.1 3.4 GO:0046732 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
1.1 6.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
1.1 4.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
1.0 11.9 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
1.0 7.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.0 4.8 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
1.0 3.8 GO:0071896 protein localization to adherens junction(GO:0071896)
1.0 1.0 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.9 3.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.9 6.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.9 6.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.9 1.7 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.9 6.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.8 2.5 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.8 0.8 GO:0090427 activation of meiosis(GO:0090427)
0.8 5.8 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.8 3.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.8 7.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.8 3.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.8 3.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.8 3.8 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402) positive regulation of synaptic vesicle clustering(GO:2000809)
0.7 2.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.7 16.8 GO:0019372 lipoxygenase pathway(GO:0019372)
0.7 11.1 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.7 7.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.7 2.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.7 4.8 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.7 0.7 GO:0035973 aggrephagy(GO:0035973)
0.7 6.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.7 8.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.7 4.6 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.6 1.9 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.6 6.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.6 1.9 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.6 1.9 GO:0060920 atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.6 4.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6 7.1 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.6 3.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.6 1.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.5 1.6 GO:0046098 hypoxanthine salvage(GO:0043103) guanine metabolic process(GO:0046098)
0.5 3.7 GO:0009597 detection of virus(GO:0009597)
0.5 2.0 GO:0042256 mature ribosome assembly(GO:0042256)
0.5 2.5 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.5 2.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.5 4.2 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
0.5 31.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.5 6.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.5 2.7 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.4 0.4 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.4 1.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.4 2.2 GO:0061136 regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032434) regulation of proteasomal protein catabolic process(GO:0061136) regulation of proteolysis involved in cellular protein catabolic process(GO:1903050)
0.4 4.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.4 2.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.4 3.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.4 2.0 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.4 1.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.4 1.2 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.4 8.5 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.4 2.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.4 3.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.4 6.0 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.4 5.6 GO:0034063 stress granule assembly(GO:0034063)
0.4 4.4 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.4 7.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.4 5.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.4 12.4 GO:0051642 centrosome localization(GO:0051642)
0.3 3.5 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.3 3.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.3 1.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.3 1.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.3 1.7 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 1.0 GO:0016240 autophagosome docking(GO:0016240)
0.3 13.1 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.3 1.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.3 2.5 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.3 4.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 4.9 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.3 3.9 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.3 1.5 GO:0090270 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.3 2.4 GO:0032808 lacrimal gland development(GO:0032808)
0.3 4.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.3 1.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 7.9 GO:0006884 cell volume homeostasis(GO:0006884)
0.3 0.8 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.3 4.2 GO:0044803 multi-organism membrane organization(GO:0044803)
0.3 12.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.3 3.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 0.8 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3 6.2 GO:0031639 plasminogen activation(GO:0031639)
0.3 3.1 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.3 3.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.2 0.7 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.2 7.2 GO:0042026 protein refolding(GO:0042026)
0.2 1.7 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2 21.6 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.2 1.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 2.4 GO:0033327 Leydig cell differentiation(GO:0033327) response to UV-A(GO:0070141)
0.2 2.7 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.2 2.6 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.2 12.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.2 1.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 6.3 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 0.5 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.2 0.7 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 1.5 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.2 1.2 GO:0021766 hippocampus development(GO:0021766)
0.2 1.8 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.2 2.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 0.4 GO:0048627 myoblast development(GO:0048627)
0.2 2.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 0.9 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 2.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 0.4 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 1.1 GO:0071233 cellular response to leucine(GO:0071233)
0.2 7.7 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.2 2.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.2 4.8 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.2 3.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 3.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 1.0 GO:1904720 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of IRE1-mediated unfolded protein response(GO:1903895) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 1.4 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 1.5 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 1.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.5 GO:0035878 nail development(GO:0035878)
0.1 1.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 3.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 3.8 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 6.9 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 3.0 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 3.3 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 17.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.8 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 5.8 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 4.2 GO:0035418 protein localization to synapse(GO:0035418)
0.1 1.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 3.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 2.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 7.3 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 2.8 GO:0050919 negative chemotaxis(GO:0050919)
0.1 1.0 GO:0006183 GTP biosynthetic process(GO:0006183)
0.1 1.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 10.9 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.1 3.1 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 2.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 1.4 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 4.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.7 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 1.9 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 3.7 GO:0051298 centrosome duplication(GO:0051298)
0.1 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.4 GO:0070966 regulation of cytoplasmic mRNA processing body assembly(GO:0010603) positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 2.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 2.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 2.3 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1 0.3 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1 1.8 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 1.1 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.1 2.9 GO:0000045 autophagosome assembly(GO:0000045)
0.0 2.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.6 GO:0060004 reflex(GO:0060004)
0.0 1.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 4.4 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 3.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 2.2 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.1 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 2.1 GO:0006284 base-excision repair(GO:0006284)
0.0 2.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 2.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.0 GO:0016577 histone demethylation(GO:0016577)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 6.6 GO:0051168 nuclear export(GO:0051168)
0.0 6.0 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.6 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 3.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 1.6 GO:0021510 spinal cord development(GO:0021510)
0.0 2.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.6 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 2.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.2 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.5 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.8 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.4 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273) positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.7 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.0 11.9 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.6 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.8 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 2.7 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.8 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.3 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.3 GO:0019932 second-messenger-mediated signaling(GO:0019932)
0.0 1.0 GO:0021987 cerebral cortex development(GO:0021987)
0.0 1.5 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.1 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 1.3 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 18.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
3.2 9.5 GO:0019034 viral replication complex(GO:0019034)
2.7 13.6 GO:0044308 axonal spine(GO:0044308)
2.4 7.1 GO:0043291 RAVE complex(GO:0043291)
2.3 7.0 GO:0097447 dendritic tree(GO:0097447)
2.3 27.8 GO:0060077 inhibitory synapse(GO:0060077)
2.0 6.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
2.0 9.8 GO:0042272 nuclear RNA export factor complex(GO:0042272)
1.9 1.9 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
1.3 12.1 GO:0072546 ER membrane protein complex(GO:0072546)
1.3 8.8 GO:0042584 chromaffin granule membrane(GO:0042584)
1.2 18.5 GO:0005916 fascia adherens(GO:0005916)
1.2 5.8 GO:0033503 HULC complex(GO:0033503)
0.9 3.6 GO:0016939 kinesin II complex(GO:0016939)
0.8 23.8 GO:0033268 node of Ranvier(GO:0033268)
0.8 19.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.8 6.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.7 9.7 GO:0097433 dense body(GO:0097433)
0.7 15.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 3.7 GO:0030891 VCB complex(GO:0030891)
0.7 10.9 GO:0090543 Flemming body(GO:0090543)
0.7 0.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.6 5.4 GO:0071439 clathrin complex(GO:0071439)
0.6 4.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.5 2.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.5 1.0 GO:1903349 omegasome membrane(GO:1903349)
0.5 7.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 18.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.5 1.5 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.5 3.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.5 8.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.5 3.8 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 1.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 6.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 4.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 2.4 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.4 11.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 1.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 2.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 6.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 3.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 12.2 GO:1904115 axon cytoplasm(GO:1904115)
0.3 1.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 1.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 0.7 GO:0000806 Y chromosome(GO:0000806)
0.2 21.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 3.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 6.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.2 5.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 1.0 GO:0001739 sex chromatin(GO:0001739)
0.2 4.9 GO:0031143 pseudopodium(GO:0031143)
0.2 1.4 GO:0097443 sorting endosome(GO:0097443)
0.2 4.0 GO:0036126 sperm flagellum(GO:0036126)
0.2 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 13.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 4.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 7.7 GO:0005771 multivesicular body(GO:0005771)
0.2 6.0 GO:0032420 stereocilium(GO:0032420)
0.2 5.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.2 3.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 23.2 GO:0005875 microtubule associated complex(GO:0005875)
0.2 6.8 GO:0045171 intercellular bridge(GO:0045171)
0.2 2.1 GO:0005577 fibrinogen complex(GO:0005577)
0.2 22.5 GO:0055037 recycling endosome(GO:0055037)
0.2 5.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 8.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 3.5 GO:0071564 npBAF complex(GO:0071564)
0.1 4.2 GO:0005921 gap junction(GO:0005921)
0.1 2.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 1.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 15.4 GO:0000922 spindle pole(GO:0000922)
0.1 3.8 GO:0070161 anchoring junction(GO:0070161)
0.1 4.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 8.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.1 GO:0048786 presynaptic active zone(GO:0048786)
0.1 2.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 15.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.9 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 13.7 GO:0030496 midbody(GO:0030496)
0.1 3.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 3.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 5.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 11.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 4.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.7 GO:0016589 NURF complex(GO:0016589)
0.1 2.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 8.4 GO:0005819 spindle(GO:0005819)
0.1 3.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.6 GO:0016592 mediator complex(GO:0016592)
0.1 3.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 3.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.1 2.4 GO:0042629 mast cell granule(GO:0042629)
0.1 4.3 GO:0031902 late endosome membrane(GO:0031902)
0.1 4.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 2.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.7 GO:0000792 heterochromatin(GO:0000792)
0.0 2.3 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 7.5 GO:0001726 ruffle(GO:0001726)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 5.5 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.5 GO:0031514 motile cilium(GO:0031514)
0.0 0.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 1.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 6.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 8.4 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 11.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 6.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.6 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 4.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 16.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.8 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
5.0 20.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
3.7 18.5 GO:0030348 syntaxin-3 binding(GO:0030348)
3.1 18.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
3.0 15.1 GO:0034046 poly(G) binding(GO:0034046)
2.6 7.7 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
2.1 6.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
2.0 6.1 GO:0032184 SUMO polymer binding(GO:0032184)
1.9 3.7 GO:0032451 demethylase activity(GO:0032451) histone demethylase activity(GO:0032452)
1.7 5.1 GO:0070699 type II activin receptor binding(GO:0070699)
1.6 15.8 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
1.5 4.5 GO:0033149 FFAT motif binding(GO:0033149)
1.3 7.6 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
1.2 1.2 GO:0043422 protein kinase B binding(GO:0043422)
1.2 7.0 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.1 4.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
1.1 7.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.1 6.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.0 25.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.9 5.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.8 3.4 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.8 5.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.8 6.0 GO:0004565 beta-galactosidase activity(GO:0004565)
0.7 8.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.7 10.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.7 9.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.7 2.1 GO:0070052 collagen V binding(GO:0070052)
0.7 4.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.7 2.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.7 3.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.7 8.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.7 10.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.6 6.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.6 1.9 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.6 16.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.6 4.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.6 1.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.6 2.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.6 5.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.6 6.7 GO:0042301 phosphate ion binding(GO:0042301)
0.6 4.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.6 1.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 10.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 2.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 10.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.4 1.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 5.5 GO:0038132 neuregulin binding(GO:0038132)
0.4 15.8 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.4 2.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.4 30.4 GO:0019003 GDP binding(GO:0019003)
0.4 18.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.4 8.5 GO:0004707 MAP kinase activity(GO:0004707)
0.4 3.8 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.4 4.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 6.0 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.4 8.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 4.2 GO:1990239 steroid hormone binding(GO:1990239)
0.3 5.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 1.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 3.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 2.9 GO:0033592 RNA strand annealing activity(GO:0033592)
0.3 3.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 3.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 0.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.3 0.8 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.3 9.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.3 3.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 2.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.3 11.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 5.3 GO:0031005 filamin binding(GO:0031005)
0.2 6.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.7 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 4.2 GO:0005522 profilin binding(GO:0005522)
0.2 3.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 11.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 4.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 15.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 1.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 7.6 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 0.7 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 6.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.9 GO:0000182 rDNA binding(GO:0000182)
0.2 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 8.5 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.2 3.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 2.8 GO:0038191 neuropilin binding(GO:0038191)
0.2 3.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 6.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 2.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 1.0 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 2.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 2.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 6.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 2.5 GO:0008483 transaminase activity(GO:0008483)
0.1 2.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 14.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.0 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 8.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 3.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 35.3 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 3.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 2.4 GO:0030552 cAMP binding(GO:0030552)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 8.8 GO:0044325 ion channel binding(GO:0044325)
0.1 1.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 3.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 4.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 18.7 GO:0005525 GTP binding(GO:0005525)
0.1 1.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 1.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.8 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.0 2.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 4.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 2.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 19.9 GO:0003779 actin binding(GO:0003779)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 2.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 7.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 8.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 18.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 2.3 GO:0020037 heme binding(GO:0020037)
0.0 1.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 4.1 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 2.7 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.8 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0047485 protein N-terminus binding(GO:0047485)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 25.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 15.2 PID IL3 PATHWAY IL3-mediated signaling events
0.4 19.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 17.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.4 14.7 PID REELIN PATHWAY Reelin signaling pathway
0.4 7.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.4 17.8 PID INSULIN PATHWAY Insulin Pathway
0.3 26.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.3 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.3 11.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 18.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 13.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 3.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 14.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 6.7 PID ARF6 PATHWAY Arf6 signaling events
0.2 13.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 2.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 3.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 2.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 9.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 8.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.5 PID FOXO PATHWAY FoxO family signaling
0.1 8.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 4.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 6.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 6.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 10.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 2.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.0 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.2 PID AURORA A PATHWAY Aurora A signaling
0.1 3.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 5.3 PID P73PATHWAY p73 transcription factor network
0.0 2.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 23.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
1.2 21.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.7 15.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.6 20.4 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.6 1.3 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.6 6.7 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.5 14.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.5 12.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.5 10.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 7.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 0.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 4.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 7.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 6.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 5.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 5.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 2.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 1.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 5.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 6.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 4.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 9.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 3.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 5.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 4.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 7.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 8.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 6.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 8.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 3.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 1.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 7.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 6.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 15.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 6.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 4.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 9.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 4.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.7 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 1.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 4.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 4.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 6.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 13.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 7.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 10.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 9.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.7 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 1.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 5.8 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 1.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.2 REACTOME S PHASE Genes involved in S Phase
0.0 0.3 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes