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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for HES1

Z-value: 0.20

Motif logo

Transcription factors associated with HES1

Gene Symbol Gene ID Gene Info
ENSG00000114315.3 hes family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES1hg19_v2_chr3_+_193853927_193853944-0.127.5e-02Click!

Activity profile of HES1 motif

Sorted Z-values of HES1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_7023491 13.21 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr3_-_138763734 9.00 ENST00000413199.1
ENST00000502927.2
proline rich 23C
chr19_-_1652575 8.86 ENST00000587235.1
ENST00000262965.5
transcription factor 3
chr12_+_7023735 8.42 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr20_-_43280325 7.55 ENST00000537820.1
adenosine deaminase
chr9_+_91926103 6.70 ENST00000314355.6
CDC28 protein kinase regulatory subunit 2
chr2_-_73511559 6.51 ENST00000521871.1
F-box protein 41
chr20_-_3154162 6.47 ENST00000360342.3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr1_-_32801825 6.13 ENST00000329421.7
MARCKS-like 1
chr5_+_156693091 6.11 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
cytoplasmic FMR1 interacting protein 2
chr16_+_2039946 5.91 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr5_+_156693159 5.73 ENST00000347377.6
cytoplasmic FMR1 interacting protein 2
chr3_+_184081137 5.63 ENST00000443489.1
polymerase (RNA) II (DNA directed) polypeptide H
chr7_-_99698338 5.49 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr7_-_148581251 5.36 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
enhancer of zeste homolog 2 (Drosophila)
chr3_+_184081175 5.27 ENST00000452961.1
ENST00000296223.3
polymerase (RNA) II (DNA directed) polypeptide H
chr17_-_3599696 5.18 ENST00000225328.5
purinergic receptor P2X, ligand-gated ion channel, 5
chr3_+_184081213 5.09 ENST00000429568.1
polymerase (RNA) II (DNA directed) polypeptide H
chr4_-_185655278 4.93 ENST00000281453.5
centromere protein U
chr3_-_47823298 4.70 ENST00000254480.5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr17_-_3599327 4.69 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr2_-_96811170 4.62 ENST00000288943.4
dual specificity phosphatase 2
chr17_-_3599492 4.61 ENST00000435558.1
ENST00000345901.3
purinergic receptor P2X, ligand-gated ion channel, 5
chr1_-_25291475 4.42 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr1_+_41445413 4.38 ENST00000541520.1
CTP synthase 1
chr15_+_89182178 4.33 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr7_-_148581360 4.29 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
enhancer of zeste homolog 2 (Drosophila)
chr2_-_10588630 4.23 ENST00000234111.4
ornithine decarboxylase 1
chr15_+_52311398 4.17 ENST00000261845.5
mitogen-activated protein kinase 6
chr19_+_34855874 4.13 ENST00000588991.2
glucose-6-phosphate isomerase
chr15_+_89182156 4.13 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr19_-_55919087 4.11 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
ubiquitin-conjugating enzyme E2S
chr17_-_57184260 4.01 ENST00000376149.3
ENST00000393066.3
tripartite motif containing 37
chr19_+_34855925 3.99 ENST00000590375.1
ENST00000356487.5
glucose-6-phosphate isomerase
chr17_-_57184064 3.94 ENST00000262294.7
tripartite motif containing 37
chr19_+_10982336 3.88 ENST00000344150.4
coactivator-associated arginine methyltransferase 1
chr14_+_100437780 3.87 ENST00000402714.2
Enah/Vasp-like
chr19_+_34856141 3.81 ENST00000586425.1
glucose-6-phosphate isomerase
chr15_+_89181974 3.79 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr21_-_44495919 3.69 ENST00000398158.1
cystathionine-beta-synthase
chr7_+_155089486 3.69 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
insulin induced gene 1
chr12_-_76478686 3.67 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr11_-_113746212 3.64 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
ubiquitin specific peptidase 28
chr19_+_10982189 3.53 ENST00000327064.4
ENST00000588947.1
coactivator-associated arginine methyltransferase 1
chr2_+_216176540 3.51 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr3_+_183415558 3.50 ENST00000305135.5
YEATS domain containing 2
chr17_-_3867585 3.47 ENST00000359983.3
ENST00000352011.3
ENST00000397043.3
ENST00000397041.3
ENST00000397035.3
ENST00000397039.1
ENST00000309890.7
ATPase, Ca++ transporting, ubiquitous
chr12_-_76478417 3.47 ENST00000552342.1
nucleosome assembly protein 1-like 1
chr1_+_91966656 3.46 ENST00000428239.1
ENST00000426137.1
cell division cycle 7
chr8_+_56014949 3.39 ENST00000327381.6
XK, Kell blood group complex subunit-related family, member 4
chr19_-_7936344 3.36 ENST00000599142.1
Protein FLJ22184
chr2_-_136633940 3.32 ENST00000264156.2
minichromosome maintenance complex component 6
chr1_-_53793725 3.26 ENST00000371454.2
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr11_-_113746277 3.21 ENST00000003302.4
ENST00000545540.1
ubiquitin specific peptidase 28
chr12_-_76478386 3.21 ENST00000535020.2
nucleosome assembly protein 1-like 1
chr9_-_131790464 3.18 ENST00000417224.1
ENST00000416629.1
ENST00000372559.1
SH3-domain GRB2-like endophilin B2
chr16_+_67596310 3.17 ENST00000264010.4
ENST00000401394.1
CCCTC-binding factor (zinc finger protein)
chr16_+_29817841 3.14 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr13_+_103249322 3.14 ENST00000376065.4
ENST00000376052.3
tripeptidyl peptidase II
chr12_-_117537240 3.13 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
tescalcin
chr9_-_101471479 3.01 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr4_+_57302297 3.00 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr12_-_49525175 2.94 ENST00000336023.5
ENST00000550367.1
ENST00000552984.1
ENST00000547476.1
tubulin, alpha 1b
chr15_-_44069741 2.94 ENST00000319359.3
elongation factor RNA polymerase II-like 3
chr3_-_148804275 2.84 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr18_-_77793891 2.84 ENST00000592957.1
ENST00000585474.1
thioredoxin-like 4A
chr22_-_37213045 2.84 ENST00000406910.2
ENST00000417718.2
parvalbumin
chr2_+_178077477 2.84 ENST00000411529.2
ENST00000435711.1
heterogeneous nuclear ribonucleoprotein A3
chr5_+_149546334 2.82 ENST00000231656.8
caudal type homeobox 1
chr20_+_55966444 2.80 ENST00000356208.5
ENST00000440234.2
RNA binding motif protein 38
chr13_-_31039375 2.78 ENST00000399494.1
high mobility group box 1
chr9_+_131451480 2.72 ENST00000322030.8
SET nuclear oncogene
chr1_+_28844778 2.72 ENST00000411533.1
regulator of chromosome condensation 1
chr20_+_35201857 2.71 ENST00000373874.2
TGFB-induced factor homeobox 2
chr5_+_61602055 2.69 ENST00000381103.2
kinesin heavy chain member 2A
chr18_+_12947981 2.69 ENST00000262124.11
SEH1-like (S. cerevisiae)
chr9_-_15510989 2.68 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PC4 and SFRS1 interacting protein 1
chr15_+_41056218 2.68 ENST00000260447.4
GTP cyclohydrolase I feedback regulator
chr12_+_131356582 2.65 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN, member RAS oncogene family
chrX_-_102319092 2.64 ENST00000372728.3
brain expressed, X-linked 1
chr12_-_125348448 2.62 ENST00000339570.5
scavenger receptor class B, member 1
chr1_-_46152174 2.59 ENST00000290795.3
ENST00000355105.3
GC-rich promoter binding protein 1-like 1
chr12_-_76478446 2.57 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
nucleosome assembly protein 1-like 1
chr11_-_46867780 2.56 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
cytoskeleton associated protein 5
chr1_+_6845384 2.55 ENST00000303635.7
calmodulin binding transcription activator 1
chr20_+_31407692 2.55 ENST00000375571.5
microtubule-associated protein, RP/EB family, member 1
chrX_-_48776292 2.52 ENST00000376509.4
pim-2 oncogene
chr14_+_105886150 2.51 ENST00000331320.7
ENST00000406191.1
metastasis associated 1
chr17_-_10101868 2.50 ENST00000432992.2
ENST00000540214.1
growth arrest-specific 7
chr1_-_101491319 2.49 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
diphthamide biosynthesis 5
chr15_+_84115868 2.48 ENST00000427482.2
SH3-domain GRB2-like 3
chr7_+_150065278 2.47 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr6_-_13711773 2.44 ENST00000011619.3
RAN binding protein 9
chr12_-_125348329 2.42 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
scavenger receptor class B, member 1
chr1_-_111743285 2.38 ENST00000357640.4
DENN/MADD domain containing 2D
chr5_+_6714718 2.37 ENST00000230859.6
ENST00000515721.1
PAP associated domain containing 7
chr10_+_3109695 2.36 ENST00000381125.4
phosphofructokinase, platelet
chr6_-_43197189 2.36 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr19_+_50887585 2.36 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
polymerase (DNA directed), delta 1, catalytic subunit
chr3_+_184080790 2.33 ENST00000430783.1
polymerase (RNA) II (DNA directed) polypeptide H
chr19_+_30302805 2.31 ENST00000262643.3
ENST00000575243.1
ENST00000357943.5
cyclin E1
chr1_-_45805667 2.29 ENST00000488731.2
ENST00000435155.1
mutY homolog
chr16_-_4466565 2.28 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16 readthrough
coronin 7
chr14_+_103243813 2.27 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TNF receptor-associated factor 3
chr3_+_23851928 2.26 ENST00000467766.1
ENST00000424381.1
ubiquitin-conjugating enzyme E2E 1
chr4_+_108911036 2.26 ENST00000505878.1
hydroxyacyl-CoA dehydrogenase
chr15_+_84116106 2.25 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr1_-_45805607 2.22 ENST00000372104.1
ENST00000448481.1
ENST00000483127.1
ENST00000528013.2
ENST00000456914.2
mutY homolog
chr19_-_48673552 2.21 ENST00000536218.1
ENST00000596549.1
ligase I, DNA, ATP-dependent
chr17_-_42402138 2.19 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
solute carrier family 25, member 39
chr14_-_51562745 2.19 ENST00000298355.3
tripartite motif containing 9
chr12_+_123319973 2.19 ENST00000253083.4
huntingtin interacting protein 1 related
chr14_+_20937538 2.18 ENST00000361505.5
ENST00000553591.1
purine nucleoside phosphorylase
chr1_-_41707778 2.16 ENST00000337495.5
ENST00000372597.1
ENST00000372596.1
sex comb on midleg homolog 1 (Drosophila)
chr1_+_225965518 2.14 ENST00000304786.7
ENST00000366839.4
ENST00000366838.1
signal recognition particle 9kDa
chr17_+_73257945 2.12 ENST00000579002.1
mitochondrial ribosomal protein S7
chr17_-_78450398 2.10 ENST00000306773.4
neuronal pentraxin I
chr2_+_232572361 2.10 ENST00000409321.1
prothymosin, alpha
chr1_+_220267429 2.10 ENST00000366922.1
ENST00000302637.5
isoleucyl-tRNA synthetase 2, mitochondrial
chr11_+_105948216 2.09 ENST00000278618.4
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr21_+_45527171 2.08 ENST00000291576.7
ENST00000456705.1
PWP2 periodic tryptophan protein homolog (yeast)
chr4_+_108910870 2.07 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
hydroxyacyl-CoA dehydrogenase
chr4_-_83351294 2.07 ENST00000502762.1
heterogeneous nuclear ribonucleoprotein D-like
chr18_+_77794446 2.05 ENST00000262197.7
ribosome binding factor A (putative)
chr22_+_32340447 2.04 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr9_+_37422663 2.03 ENST00000318158.6
ENST00000607784.1
glyoxylate reductase/hydroxypyruvate reductase
chr7_+_73703728 2.02 ENST00000361545.5
ENST00000223398.6
CAP-GLY domain containing linker protein 2
chr18_+_77794358 2.02 ENST00000306735.5
ribosome binding factor A (putative)
chr16_-_4466622 2.01 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
coronin 7
chr9_-_131790550 1.97 ENST00000372554.4
ENST00000372564.3
SH3-domain GRB2-like endophilin B2
chr4_-_24586140 1.97 ENST00000336812.4
DEAH (Asp-Glu-Ala-His) box helicase 15
chrX_+_101380642 1.97 ENST00000372780.1
ENST00000329035.2
transcription elongation factor A (SII)-like 2
chr11_+_64863587 1.96 ENST00000530773.1
ENST00000279281.3
ENST00000529180.1
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr4_+_83351715 1.95 ENST00000273920.3
enolase-phosphatase 1
chr20_+_35201993 1.94 ENST00000373872.4
TGFB-induced factor homeobox 2
chr11_+_46354455 1.94 ENST00000343674.6
diacylglycerol kinase, zeta
chr6_-_90529418 1.91 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1, midasin homolog (yeast)
chr17_+_73257742 1.91 ENST00000579761.1
ENST00000245539.6
mitochondrial ribosomal protein S7
chr4_+_83351791 1.90 ENST00000509635.1
enolase-phosphatase 1
chr8_-_145515055 1.89 ENST00000526552.1
ENST00000529231.1
ENST00000307404.5
block of proliferation 1
chr15_-_58357932 1.89 ENST00000347587.3
aldehyde dehydrogenase 1 family, member A2
chr19_+_49622646 1.86 ENST00000334186.4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr6_-_13814663 1.86 ENST00000359495.2
ENST00000379170.4
mitochondrial calcium uniporter regulator 1
chr1_+_111682827 1.84 ENST00000357172.4
choline/ethanolamine phosphotransferase 1
chr11_+_64004888 1.83 ENST00000541681.1
vascular endothelial growth factor B
chr9_+_132427883 1.83 ENST00000372469.4
paired related homeobox 2
chr3_-_47619623 1.82 ENST00000456150.1
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr16_+_85646891 1.81 ENST00000393243.1
Gse1 coiled-coil protein
chr1_-_23670752 1.80 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
heterogeneous nuclear ribonucleoprotein R
chr3_-_13009168 1.80 ENST00000273221.4
IQ motif and Sec7 domain 1
chr12_-_93835665 1.80 ENST00000552442.1
ENST00000550657.1
ubiquitin-conjugating enzyme E2N
chr6_+_157802165 1.79 ENST00000414563.2
ENST00000359775.5
zinc finger, DHHC-type containing 14
chr1_+_165797024 1.79 ENST00000372212.4
uridine-cytidine kinase 2
chr21_-_38445443 1.76 ENST00000360525.4
phosphatidylinositol glycan anchor biosynthesis, class P
chr22_+_50247449 1.76 ENST00000216268.5
zinc finger, BED-type containing 4
chr21_-_44495964 1.76 ENST00000398168.1
ENST00000398165.3
cystathionine-beta-synthase
chr1_-_45805752 1.73 ENST00000354383.6
ENST00000355498.2
ENST00000372100.5
ENST00000531105.1
mutY homolog
chr11_+_1968508 1.73 ENST00000397298.3
ENST00000381519.1
ENST00000397297.3
ENST00000381514.3
ENST00000397294.3
mitochondrial ribosomal protein L23
chr8_+_85097110 1.72 ENST00000517638.1
ENST00000522647.1
RALY RNA binding protein-like
chr4_+_17812525 1.72 ENST00000251496.2
non-SMC condensin I complex, subunit G
chr3_-_121553830 1.71 ENST00000498104.1
ENST00000460108.1
ENST00000349820.6
ENST00000462442.1
ENST00000310864.6
IQ motif containing B1
chr19_+_8509842 1.70 ENST00000325495.4
ENST00000600092.1
ENST00000594907.1
ENST00000596984.1
ENST00000601645.1
heterogeneous nuclear ribonucleoprotein M
chr19_-_8386238 1.70 ENST00000301457.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr17_+_8191815 1.69 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr16_+_85646763 1.69 ENST00000411612.1
ENST00000253458.7
Gse1 coiled-coil protein
chr21_-_10990830 1.68 ENST00000361285.4
ENST00000342420.5
ENST00000328758.5
transmembrane phosphatase with tensin homology
chr7_+_106685079 1.67 ENST00000265717.4
protein kinase, cAMP-dependent, regulatory, type II, beta
chr3_-_10749696 1.67 ENST00000397077.1
ATPase, Ca++ transporting, plasma membrane 2
chr22_+_32340481 1.66 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr3_+_49058444 1.66 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr2_-_136743039 1.65 ENST00000537273.1
aspartyl-tRNA synthetase
chr20_+_11871433 1.64 ENST00000399006.2
ENST00000405977.1
BTB (POZ) domain containing 3
chr5_-_7869108 1.63 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FAST kinase domains 3
chr21_-_10990888 1.63 ENST00000298232.7
transmembrane phosphatase with tensin homology
chr3_-_133380731 1.63 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr1_-_23670813 1.62 ENST00000374612.1
heterogeneous nuclear ribonucleoprotein R
chr1_-_92949505 1.62 ENST00000370332.1
growth factor independent 1 transcription repressor
chr22_+_29664248 1.62 ENST00000406548.1
ENST00000437155.2
ENST00000415761.1
ENST00000331029.7
EWS RNA-binding protein 1
chr9_-_111696224 1.62 ENST00000537196.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr20_+_11871371 1.59 ENST00000254977.3
BTB (POZ) domain containing 3
chr7_+_99775366 1.58 ENST00000394018.2
ENST00000416412.1
stromal antigen 3
chr13_-_41635512 1.58 ENST00000405737.2
E74-like factor 1 (ets domain transcription factor)
chr19_+_50353944 1.57 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
prostate tumor overexpressed 1
chr6_-_125623046 1.56 ENST00000608295.1
ENST00000398153.2
ENST00000608284.1
ENST00000368377.4
HD domain containing 2
chr5_-_78809950 1.55 ENST00000334082.6
homer homolog 1 (Drosophila)
chr7_+_102073966 1.55 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
ORAI calcium release-activated calcium modulator 2
chr14_-_105635090 1.54 ENST00000331782.3
ENST00000347004.2
jagged 2
chr10_-_121302195 1.54 ENST00000369103.2
regulator of G-protein signaling 10
chr11_-_134093827 1.53 ENST00000534548.2
non-SMC condensin II complex, subunit D3
chr16_+_11038345 1.52 ENST00000409790.1
C-type lectin domain family 16, member A
chr7_+_73588665 1.52 ENST00000353999.6
eukaryotic translation initiation factor 4H
chr22_+_20105259 1.52 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr11_+_86748863 1.51 ENST00000340353.7
transmembrane protein 135
chr15_-_90645679 1.50 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr13_-_39612176 1.50 ENST00000352251.3
ENST00000350125.3
proline and serine rich 1
chr2_+_232575128 1.50 ENST00000412128.1
prothymosin, alpha
chr3_+_8775466 1.48 ENST00000343849.2
ENST00000397368.2
caveolin 3
chr2_-_70529180 1.47 ENST00000450256.1
ENST00000037869.3
family with sequence similarity 136, member A
chr14_+_50234309 1.47 ENST00000298307.5
kelch domain containing 2
chr1_-_154531095 1.46 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HES1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
4.0 11.9 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
3.2 9.7 GO:0046102 inosine metabolic process(GO:0046102)
3.2 9.6 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
2.9 2.9 GO:0070670 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
2.6 7.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
1.8 5.4 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
1.7 5.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
1.5 7.4 GO:0034971 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R17 methylation(GO:0034971)
1.5 11.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.5 4.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
1.4 4.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
1.2 3.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.2 4.8 GO:0046452 dihydrofolate metabolic process(GO:0046452)
1.1 3.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.1 8.9 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
1.1 7.6 GO:0045007 depurination(GO:0045007)
1.1 4.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
1.1 3.2 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
1.0 3.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.9 2.7 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.9 8.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.9 3.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.8 2.5 GO:0061198 fungiform papilla formation(GO:0061198)
0.8 2.5 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.8 4.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.7 2.2 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.7 2.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.7 2.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.7 2.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.7 2.8 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.7 2.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.7 2.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.7 5.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.6 1.8 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.6 2.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.5 2.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.5 1.6 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.5 3.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.5 1.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.5 24.1 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.5 1.5 GO:0006097 glyoxylate cycle(GO:0006097)
0.5 2.9 GO:0044211 CTP salvage(GO:0044211)
0.5 1.9 GO:0002572 pro-T cell differentiation(GO:0002572)
0.5 1.9 GO:0032053 ciliary basal body organization(GO:0032053)
0.5 1.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.5 1.8 GO:0019086 late viral transcription(GO:0019086)
0.5 14.3 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.5 2.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.5 2.3 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.4 3.1 GO:0035799 ureter maturation(GO:0035799)
0.4 2.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.4 4.0 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.4 2.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.4 3.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 3.9 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4 2.1 GO:0072553 terminal button organization(GO:0072553)
0.4 1.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.4 18.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.4 2.8 GO:1902570 protein localization to nucleolus(GO:1902570)
0.4 1.2 GO:0046098 guanine metabolic process(GO:0046098)
0.4 3.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.4 1.5 GO:0018094 protein polyglycylation(GO:0018094)
0.4 1.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.4 0.4 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.4 1.1 GO:0100009 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.4 3.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.4 5.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.4 2.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.4 1.1 GO:0008355 olfactory learning(GO:0008355)
0.4 1.1 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.4 1.5 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.4 4.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.3 1.3 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.3 1.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 1.7 GO:0097338 response to clozapine(GO:0097338)
0.3 2.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.3 1.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 3.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 2.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.3 2.5 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3 1.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.3 1.2 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 2.7 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.3 1.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.3 2.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 7.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 0.9 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 2.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 1.1 GO:0001743 optic placode formation(GO:0001743) axial mesoderm morphogenesis(GO:0048319)
0.3 0.8 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.3 7.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 1.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.3 1.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 2.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.3 1.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 1.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 2.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 0.8 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.2 0.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 0.2 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2 2.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 5.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 4.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 0.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 3.7 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 1.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 6.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 2.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 2.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.4 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.2 0.6 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.2 0.6 GO:0098502 DNA dephosphorylation(GO:0098502)
0.2 1.8 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.2 1.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 1.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 0.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 4.7 GO:0061157 mRNA destabilization(GO:0061157)
0.2 1.9 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 0.6 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 1.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 0.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 1.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 0.5 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 0.7 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.2 0.5 GO:0021586 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 0.5 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 1.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.2 1.0 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 4.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 1.8 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.2 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 1.5 GO:0070459 prolactin secretion(GO:0070459)
0.2 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 1.4 GO:1902415 regulation of mRNA binding(GO:1902415)
0.2 1.6 GO:0015889 cobalamin transport(GO:0015889)
0.2 1.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 1.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 2.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 2.9 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.2 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.8 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 4.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.6 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 1.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 1.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.1 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.5 GO:1904628 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 2.1 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 1.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.6 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 1.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 7.0 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 4.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 4.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.8 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.1 0.7 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.7 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 14.4 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.9 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 2.4 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.4 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 1.5 GO:0014029 neural crest formation(GO:0014029)
0.1 1.4 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 1.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 3.5 GO:0006270 DNA replication initiation(GO:0006270)
0.1 4.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.8 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 1.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 1.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 6.0 GO:0021762 substantia nigra development(GO:0021762)
0.1 0.5 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 1.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.5 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.7 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.6 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.0 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.7 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.1 0.4 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 2.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.2 GO:0071287 phytoalexin metabolic process(GO:0052314) cellular response to manganese ion(GO:0071287)
0.1 1.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 1.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.9 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1 0.4 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 1.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.3 GO:2000410 regulation of thymocyte migration(GO:2000410)
0.1 1.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.8 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 1.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.6 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.6 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.1 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 1.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:2000724 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 2.4 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.8 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.1 1.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.1 0.4 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.1 0.2 GO:2000275 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) regulation of oxidative phosphorylation uncoupler activity(GO:2000275) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.4 GO:0014050 negative regulation of glutamate secretion(GO:0014050) negative regulation of serotonin secretion(GO:0014063)
0.1 1.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.5 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.1 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.1 2.8 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.2 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 1.6 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 3.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 4.0 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.6 GO:0046036 UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.1 0.9 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.4 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 4.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.4 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.3 GO:0051013 microtubule severing(GO:0051013)
0.1 2.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.7 GO:0051683 establishment of Golgi localization(GO:0051683) Golgi reassembly(GO:0090168)
0.0 0.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.2 GO:0035640 exploration behavior(GO:0035640)
0.0 0.5 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.0 0.3 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.5 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 1.3 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.3 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 1.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0015791 polyol transport(GO:0015791)
0.0 0.4 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.8 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.9 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.6 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 3.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 2.1 GO:0045453 bone resorption(GO:0045453)
0.0 0.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 10.4 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 6.3 GO:0006364 rRNA processing(GO:0006364)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) regulation of DNA methylation(GO:0044030)
0.0 0.7 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 3.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.9 GO:0006260 DNA replication(GO:0006260)
0.0 0.1 GO:1902268 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.9 GO:0007140 male meiosis(GO:0007140)
0.0 0.1 GO:1901374 acetate ester transport(GO:1901374)
0.0 1.6 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.5 GO:0043065 positive regulation of apoptotic process(GO:0043065)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 2.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.8 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.7 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 1.5 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.9 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.1 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 3.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.5 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229)
0.0 0.6 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 1.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.6 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 21.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.0 18.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.0 3.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.9 3.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.9 22.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.8 2.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.7 2.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.6 2.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.6 8.4 GO:0042555 MCM complex(GO:0042555)
0.6 1.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.6 2.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.6 2.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.5 2.0 GO:0000811 GINS complex(GO:0000811)
0.5 2.0 GO:1990745 EARP complex(GO:1990745)
0.5 2.3 GO:0001940 male pronucleus(GO:0001940)
0.5 1.8 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.4 0.9 GO:0033186 CAF-1 complex(GO:0033186)
0.4 2.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 2.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 2.7 GO:0061700 GATOR2 complex(GO:0061700)
0.4 1.5 GO:0000799 nuclear condensin complex(GO:0000799)
0.3 3.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 1.9 GO:0070545 PeBoW complex(GO:0070545)
0.3 4.7 GO:0001741 XY body(GO:0001741)
0.3 2.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.3 1.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 1.7 GO:0000796 condensin complex(GO:0000796)
0.3 8.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 1.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.1 GO:0030314 junctional membrane complex(GO:0030314)
0.3 1.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.3 1.6 GO:0030893 meiotic cohesin complex(GO:0030893)
0.2 4.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 4.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.2 12.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 1.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 1.1 GO:1902555 endoribonuclease complex(GO:1902555)
0.2 1.7 GO:0042382 paraspeckles(GO:0042382)
0.2 5.5 GO:0035371 microtubule plus-end(GO:0035371)
0.2 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 3.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 12.9 GO:0015030 Cajal body(GO:0015030)
0.2 3.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 2.6 GO:0090543 Flemming body(GO:0090543)
0.2 1.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 3.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 1.8 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.2 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 2.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 4.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.2 GO:0010369 chromocenter(GO:0010369)
0.1 1.1 GO:0005642 annulate lamellae(GO:0005642)
0.1 3.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 4.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.6