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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for HES1
Z-value: 0.20
Motif logo
Transcription factors associated with HES1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HES1
|
ENSG00000114315.3 | hes family bHLH transcription factor 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HES1 | hg19_v2_chr3_+_193853927_193853944 | -0.12 | 7.5e-02 | Click! |
Activity profile of HES1 motif
Sorted Z-values of HES1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_+_7023491 | 13.21 |
ENST00000541477.1
ENST00000229277.1 |
ENO2
|
enolase 2 (gamma, neuronal) |
| chr3_-_138763734 | 9.00 |
ENST00000413199.1
ENST00000502927.2 |
PRR23C
|
proline rich 23C |
| chr19_-_1652575 | 8.86 |
ENST00000587235.1
ENST00000262965.5 |
TCF3
|
transcription factor 3 |
| chr12_+_7023735 | 8.42 |
ENST00000538763.1
ENST00000544774.1 ENST00000545045.2 |
ENO2
|
enolase 2 (gamma, neuronal) |
| chr20_-_43280325 | 7.55 |
ENST00000537820.1
|
ADA
|
adenosine deaminase |
| chr9_+_91926103 | 6.70 |
ENST00000314355.6
|
CKS2
|
CDC28 protein kinase regulatory subunit 2 |
| chr2_-_73511559 | 6.51 |
ENST00000521871.1
|
FBXO41
|
F-box protein 41 |
| chr20_-_3154162 | 6.47 |
ENST00000360342.3
|
LZTS3
|
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA. |
| chr1_-_32801825 | 6.13 |
ENST00000329421.7
|
MARCKSL1
|
MARCKS-like 1 |
| chr5_+_156693091 | 6.11 |
ENST00000318218.6
ENST00000442283.2 ENST00000522463.1 ENST00000521420.1 |
CYFIP2
|
cytoplasmic FMR1 interacting protein 2 |
| chr16_+_2039946 | 5.91 |
ENST00000248121.2
ENST00000568896.1 |
SYNGR3
|
synaptogyrin 3 |
| chr5_+_156693159 | 5.73 |
ENST00000347377.6
|
CYFIP2
|
cytoplasmic FMR1 interacting protein 2 |
| chr3_+_184081137 | 5.63 |
ENST00000443489.1
|
POLR2H
|
polymerase (RNA) II (DNA directed) polypeptide H |
| chr7_-_99698338 | 5.49 |
ENST00000354230.3
ENST00000425308.1 |
MCM7
|
minichromosome maintenance complex component 7 |
| chr7_-_148581251 | 5.36 |
ENST00000478654.1
ENST00000460911.1 ENST00000350995.2 |
EZH2
|
enhancer of zeste homolog 2 (Drosophila) |
| chr3_+_184081175 | 5.27 |
ENST00000452961.1
ENST00000296223.3 |
POLR2H
|
polymerase (RNA) II (DNA directed) polypeptide H |
| chr17_-_3599696 | 5.18 |
ENST00000225328.5
|
P2RX5
|
purinergic receptor P2X, ligand-gated ion channel, 5 |
| chr3_+_184081213 | 5.09 |
ENST00000429568.1
|
POLR2H
|
polymerase (RNA) II (DNA directed) polypeptide H |
| chr4_-_185655278 | 4.93 |
ENST00000281453.5
|
MLF1IP
|
centromere protein U |
| chr3_-_47823298 | 4.70 |
ENST00000254480.5
|
SMARCC1
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 |
| chr17_-_3599327 | 4.69 |
ENST00000551178.1
ENST00000552276.1 ENST00000547178.1 |
P2RX5
|
purinergic receptor P2X, ligand-gated ion channel, 5 |
| chr2_-_96811170 | 4.62 |
ENST00000288943.4
|
DUSP2
|
dual specificity phosphatase 2 |
| chr17_-_3599492 | 4.61 |
ENST00000435558.1
ENST00000345901.3 |
P2RX5
|
purinergic receptor P2X, ligand-gated ion channel, 5 |
| chr1_-_25291475 | 4.42 |
ENST00000338888.3
ENST00000399916.1 |
RUNX3
|
runt-related transcription factor 3 |
| chr1_+_41445413 | 4.38 |
ENST00000541520.1
|
CTPS1
|
CTP synthase 1 |
| chr15_+_89182178 | 4.33 |
ENST00000559876.1
|
ISG20
|
interferon stimulated exonuclease gene 20kDa |
| chr7_-_148581360 | 4.29 |
ENST00000320356.2
ENST00000541220.1 ENST00000483967.1 ENST00000536783.1 |
EZH2
|
enhancer of zeste homolog 2 (Drosophila) |
| chr2_-_10588630 | 4.23 |
ENST00000234111.4
|
ODC1
|
ornithine decarboxylase 1 |
| chr15_+_52311398 | 4.17 |
ENST00000261845.5
|
MAPK6
|
mitogen-activated protein kinase 6 |
| chr19_+_34855874 | 4.13 |
ENST00000588991.2
|
GPI
|
glucose-6-phosphate isomerase |
| chr15_+_89182156 | 4.13 |
ENST00000379224.5
|
ISG20
|
interferon stimulated exonuclease gene 20kDa |
| chr19_-_55919087 | 4.11 |
ENST00000587845.1
ENST00000589978.1 ENST00000264552.9 |
UBE2S
|
ubiquitin-conjugating enzyme E2S |
| chr17_-_57184260 | 4.01 |
ENST00000376149.3
ENST00000393066.3 |
TRIM37
|
tripartite motif containing 37 |
| chr19_+_34855925 | 3.99 |
ENST00000590375.1
ENST00000356487.5 |
GPI
|
glucose-6-phosphate isomerase |
| chr17_-_57184064 | 3.94 |
ENST00000262294.7
|
TRIM37
|
tripartite motif containing 37 |
| chr19_+_10982336 | 3.88 |
ENST00000344150.4
|
CARM1
|
coactivator-associated arginine methyltransferase 1 |
| chr14_+_100437780 | 3.87 |
ENST00000402714.2
|
EVL
|
Enah/Vasp-like |
| chr19_+_34856141 | 3.81 |
ENST00000586425.1
|
GPI
|
glucose-6-phosphate isomerase |
| chr15_+_89181974 | 3.79 |
ENST00000306072.5
|
ISG20
|
interferon stimulated exonuclease gene 20kDa |
| chr21_-_44495919 | 3.69 |
ENST00000398158.1
|
CBS
|
cystathionine-beta-synthase |
| chr7_+_155089486 | 3.69 |
ENST00000340368.4
ENST00000344756.4 ENST00000425172.1 ENST00000342407.5 |
INSIG1
|
insulin induced gene 1 |
| chr12_-_76478686 | 3.67 |
ENST00000261182.8
|
NAP1L1
|
nucleosome assembly protein 1-like 1 |
| chr11_-_113746212 | 3.64 |
ENST00000537642.1
ENST00000537706.1 ENST00000544750.1 ENST00000260188.5 ENST00000540925.1 |
USP28
|
ubiquitin specific peptidase 28 |
| chr19_+_10982189 | 3.53 |
ENST00000327064.4
ENST00000588947.1 |
CARM1
|
coactivator-associated arginine methyltransferase 1 |
| chr2_+_216176540 | 3.51 |
ENST00000236959.9
|
ATIC
|
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| chr3_+_183415558 | 3.50 |
ENST00000305135.5
|
YEATS2
|
YEATS domain containing 2 |
| chr17_-_3867585 | 3.47 |
ENST00000359983.3
ENST00000352011.3 ENST00000397043.3 ENST00000397041.3 ENST00000397035.3 ENST00000397039.1 ENST00000309890.7 |
ATP2A3
|
ATPase, Ca++ transporting, ubiquitous |
| chr12_-_76478417 | 3.47 |
ENST00000552342.1
|
NAP1L1
|
nucleosome assembly protein 1-like 1 |
| chr1_+_91966656 | 3.46 |
ENST00000428239.1
ENST00000426137.1 |
CDC7
|
cell division cycle 7 |
| chr8_+_56014949 | 3.39 |
ENST00000327381.6
|
XKR4
|
XK, Kell blood group complex subunit-related family, member 4 |
| chr19_-_7936344 | 3.36 |
ENST00000599142.1
|
CTD-3193O13.9
|
Protein FLJ22184 |
| chr2_-_136633940 | 3.32 |
ENST00000264156.2
|
MCM6
|
minichromosome maintenance complex component 6 |
| chr1_-_53793725 | 3.26 |
ENST00000371454.2
|
LRP8
|
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor |
| chr11_-_113746277 | 3.21 |
ENST00000003302.4
ENST00000545540.1 |
USP28
|
ubiquitin specific peptidase 28 |
| chr12_-_76478386 | 3.21 |
ENST00000535020.2
|
NAP1L1
|
nucleosome assembly protein 1-like 1 |
| chr9_-_131790464 | 3.18 |
ENST00000417224.1
ENST00000416629.1 ENST00000372559.1 |
SH3GLB2
|
SH3-domain GRB2-like endophilin B2 |
| chr16_+_67596310 | 3.17 |
ENST00000264010.4
ENST00000401394.1 |
CTCF
|
CCCTC-binding factor (zinc finger protein) |
| chr16_+_29817841 | 3.14 |
ENST00000322945.6
ENST00000562337.1 ENST00000566906.2 ENST00000563402.1 ENST00000219782.6 |
MAZ
|
MYC-associated zinc finger protein (purine-binding transcription factor) |
| chr13_+_103249322 | 3.14 |
ENST00000376065.4
ENST00000376052.3 |
TPP2
|
tripeptidyl peptidase II |
| chr12_-_117537240 | 3.13 |
ENST00000392545.4
ENST00000541210.1 ENST00000335209.7 |
TESC
|
tescalcin |
| chr9_-_101471479 | 3.01 |
ENST00000259455.2
|
GABBR2
|
gamma-aminobutyric acid (GABA) B receptor, 2 |
| chr4_+_57302297 | 3.00 |
ENST00000399688.3
ENST00000512576.1 |
PAICS
|
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| chr12_-_49525175 | 2.94 |
ENST00000336023.5
ENST00000550367.1 ENST00000552984.1 ENST00000547476.1 |
TUBA1B
|
tubulin, alpha 1b |
| chr15_-_44069741 | 2.94 |
ENST00000319359.3
|
ELL3
|
elongation factor RNA polymerase II-like 3 |
| chr3_-_148804275 | 2.84 |
ENST00000392912.2
ENST00000465259.1 ENST00000310053.5 ENST00000494055.1 |
HLTF
|
helicase-like transcription factor |
| chr18_-_77793891 | 2.84 |
ENST00000592957.1
ENST00000585474.1 |
TXNL4A
|
thioredoxin-like 4A |
| chr22_-_37213045 | 2.84 |
ENST00000406910.2
ENST00000417718.2 |
PVALB
|
parvalbumin |
| chr2_+_178077477 | 2.84 |
ENST00000411529.2
ENST00000435711.1 |
HNRNPA3
|
heterogeneous nuclear ribonucleoprotein A3 |
| chr5_+_149546334 | 2.82 |
ENST00000231656.8
|
CDX1
|
caudal type homeobox 1 |
| chr20_+_55966444 | 2.80 |
ENST00000356208.5
ENST00000440234.2 |
RBM38
|
RNA binding motif protein 38 |
| chr13_-_31039375 | 2.78 |
ENST00000399494.1
|
HMGB1
|
high mobility group box 1 |
| chr9_+_131451480 | 2.72 |
ENST00000322030.8
|
SET
|
SET nuclear oncogene |
| chr1_+_28844778 | 2.72 |
ENST00000411533.1
|
RCC1
|
regulator of chromosome condensation 1 |
| chr20_+_35201857 | 2.71 |
ENST00000373874.2
|
TGIF2
|
TGFB-induced factor homeobox 2 |
| chr5_+_61602055 | 2.69 |
ENST00000381103.2
|
KIF2A
|
kinesin heavy chain member 2A |
| chr18_+_12947981 | 2.69 |
ENST00000262124.11
|
SEH1L
|
SEH1-like (S. cerevisiae) |
| chr9_-_15510989 | 2.68 |
ENST00000380715.1
ENST00000380716.4 ENST00000380738.4 ENST00000380733.4 |
PSIP1
|
PC4 and SFRS1 interacting protein 1 |
| chr15_+_41056218 | 2.68 |
ENST00000260447.4
|
GCHFR
|
GTP cyclohydrolase I feedback regulator |
| chr12_+_131356582 | 2.65 |
ENST00000448750.3
ENST00000541630.1 ENST00000392369.2 ENST00000254675.3 ENST00000535090.1 ENST00000392367.3 |
RAN
|
RAN, member RAS oncogene family |
| chrX_-_102319092 | 2.64 |
ENST00000372728.3
|
BEX1
|
brain expressed, X-linked 1 |
| chr12_-_125348448 | 2.62 |
ENST00000339570.5
|
SCARB1
|
scavenger receptor class B, member 1 |
| chr1_-_46152174 | 2.59 |
ENST00000290795.3
ENST00000355105.3 |
GPBP1L1
|
GC-rich promoter binding protein 1-like 1 |
| chr12_-_76478446 | 2.57 |
ENST00000393263.3
ENST00000548044.1 ENST00000547704.1 ENST00000431879.3 ENST00000549596.1 ENST00000550934.1 ENST00000551600.1 ENST00000547479.1 ENST00000547773.1 ENST00000544816.1 ENST00000542344.1 ENST00000548273.1 |
NAP1L1
|
nucleosome assembly protein 1-like 1 |
| chr11_-_46867780 | 2.56 |
ENST00000529230.1
ENST00000415402.1 ENST00000312055.5 |
CKAP5
|
cytoskeleton associated protein 5 |
| chr1_+_6845384 | 2.55 |
ENST00000303635.7
|
CAMTA1
|
calmodulin binding transcription activator 1 |
| chr20_+_31407692 | 2.55 |
ENST00000375571.5
|
MAPRE1
|
microtubule-associated protein, RP/EB family, member 1 |
| chrX_-_48776292 | 2.52 |
ENST00000376509.4
|
PIM2
|
pim-2 oncogene |
| chr14_+_105886150 | 2.51 |
ENST00000331320.7
ENST00000406191.1 |
MTA1
|
metastasis associated 1 |
| chr17_-_10101868 | 2.50 |
ENST00000432992.2
ENST00000540214.1 |
GAS7
|
growth arrest-specific 7 |
| chr1_-_101491319 | 2.49 |
ENST00000342173.7
ENST00000488176.1 ENST00000370109.3 |
DPH5
|
diphthamide biosynthesis 5 |
| chr15_+_84115868 | 2.48 |
ENST00000427482.2
|
SH3GL3
|
SH3-domain GRB2-like 3 |
| chr7_+_150065278 | 2.47 |
ENST00000519397.1
ENST00000479668.1 ENST00000540729.1 |
REPIN1
|
replication initiator 1 |
| chr6_-_13711773 | 2.44 |
ENST00000011619.3
|
RANBP9
|
RAN binding protein 9 |
| chr12_-_125348329 | 2.42 |
ENST00000546215.1
ENST00000415380.2 ENST00000261693.6 ENST00000376788.1 ENST00000545493.1 |
SCARB1
|
scavenger receptor class B, member 1 |
| chr1_-_111743285 | 2.38 |
ENST00000357640.4
|
DENND2D
|
DENN/MADD domain containing 2D |
| chr5_+_6714718 | 2.37 |
ENST00000230859.6
ENST00000515721.1 |
PAPD7
|
PAP associated domain containing 7 |
| chr10_+_3109695 | 2.36 |
ENST00000381125.4
|
PFKP
|
phosphofructokinase, platelet |
| chr6_-_43197189 | 2.36 |
ENST00000509253.1
ENST00000393987.2 ENST00000230431.6 |
DNPH1
|
2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| chr19_+_50887585 | 2.36 |
ENST00000440232.2
ENST00000601098.1 ENST00000599857.1 ENST00000593887.1 |
POLD1
|
polymerase (DNA directed), delta 1, catalytic subunit |
| chr3_+_184080790 | 2.33 |
ENST00000430783.1
|
POLR2H
|
polymerase (RNA) II (DNA directed) polypeptide H |
| chr19_+_30302805 | 2.31 |
ENST00000262643.3
ENST00000575243.1 ENST00000357943.5 |
CCNE1
|
cyclin E1 |
| chr1_-_45805667 | 2.29 |
ENST00000488731.2
ENST00000435155.1 |
MUTYH
|
mutY homolog |
| chr16_-_4466565 | 2.28 |
ENST00000572467.1
ENST00000423908.2 ENST00000572044.1 ENST00000571052.1 |
CORO7-PAM16
CORO7
|
CORO7-PAM16 readthrough coronin 7 |
| chr14_+_103243813 | 2.27 |
ENST00000560371.1
ENST00000347662.4 ENST00000392745.2 ENST00000539721.1 ENST00000560463.1 |
TRAF3
|
TNF receptor-associated factor 3 |
| chr3_+_23851928 | 2.26 |
ENST00000467766.1
ENST00000424381.1 |
UBE2E1
|
ubiquitin-conjugating enzyme E2E 1 |
| chr4_+_108911036 | 2.26 |
ENST00000505878.1
|
HADH
|
hydroxyacyl-CoA dehydrogenase |
| chr15_+_84116106 | 2.25 |
ENST00000535412.1
ENST00000324537.5 |
SH3GL3
|
SH3-domain GRB2-like 3 |
| chr1_-_45805607 | 2.22 |
ENST00000372104.1
ENST00000448481.1 ENST00000483127.1 ENST00000528013.2 ENST00000456914.2 |
MUTYH
|
mutY homolog |
| chr19_-_48673552 | 2.21 |
ENST00000536218.1
ENST00000596549.1 |
LIG1
|
ligase I, DNA, ATP-dependent |
| chr17_-_42402138 | 2.19 |
ENST00000592857.1
ENST00000586016.1 ENST00000590194.1 ENST00000377095.5 ENST00000588049.1 ENST00000586633.1 ENST00000537904.2 ENST00000585636.1 ENST00000585523.1 ENST00000225308.8 |
SLC25A39
|
solute carrier family 25, member 39 |
| chr14_-_51562745 | 2.19 |
ENST00000298355.3
|
TRIM9
|
tripartite motif containing 9 |
| chr12_+_123319973 | 2.19 |
ENST00000253083.4
|
HIP1R
|
huntingtin interacting protein 1 related |
| chr14_+_20937538 | 2.18 |
ENST00000361505.5
ENST00000553591.1 |
PNP
|
purine nucleoside phosphorylase |
| chr1_-_41707778 | 2.16 |
ENST00000337495.5
ENST00000372597.1 ENST00000372596.1 |
SCMH1
|
sex comb on midleg homolog 1 (Drosophila) |
| chr1_+_225965518 | 2.14 |
ENST00000304786.7
ENST00000366839.4 ENST00000366838.1 |
SRP9
|
signal recognition particle 9kDa |
| chr17_+_73257945 | 2.12 |
ENST00000579002.1
|
MRPS7
|
mitochondrial ribosomal protein S7 |
| chr17_-_78450398 | 2.10 |
ENST00000306773.4
|
NPTX1
|
neuronal pentraxin I |
| chr2_+_232572361 | 2.10 |
ENST00000409321.1
|
PTMA
|
prothymosin, alpha |
| chr1_+_220267429 | 2.10 |
ENST00000366922.1
ENST00000302637.5 |
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial |
| chr11_+_105948216 | 2.09 |
ENST00000278618.4
|
AASDHPPT
|
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
| chr21_+_45527171 | 2.08 |
ENST00000291576.7
ENST00000456705.1 |
PWP2
|
PWP2 periodic tryptophan protein homolog (yeast) |
| chr4_+_108910870 | 2.07 |
ENST00000403312.1
ENST00000603302.1 ENST00000309522.3 |
HADH
|
hydroxyacyl-CoA dehydrogenase |
| chr4_-_83351294 | 2.07 |
ENST00000502762.1
|
HNRNPDL
|
heterogeneous nuclear ribonucleoprotein D-like |
| chr18_+_77794446 | 2.05 |
ENST00000262197.7
|
RBFA
|
ribosome binding factor A (putative) |
| chr22_+_32340447 | 2.04 |
ENST00000248975.5
|
YWHAH
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| chr9_+_37422663 | 2.03 |
ENST00000318158.6
ENST00000607784.1 |
GRHPR
|
glyoxylate reductase/hydroxypyruvate reductase |
| chr7_+_73703728 | 2.02 |
ENST00000361545.5
ENST00000223398.6 |
CLIP2
|
CAP-GLY domain containing linker protein 2 |
| chr18_+_77794358 | 2.02 |
ENST00000306735.5
|
RBFA
|
ribosome binding factor A (putative) |
| chr16_-_4466622 | 2.01 |
ENST00000570645.1
ENST00000574025.1 ENST00000572898.1 ENST00000537233.2 ENST00000571059.1 ENST00000251166.4 |
CORO7
|
coronin 7 |
| chr9_-_131790550 | 1.97 |
ENST00000372554.4
ENST00000372564.3 |
SH3GLB2
|
SH3-domain GRB2-like endophilin B2 |
| chr4_-_24586140 | 1.97 |
ENST00000336812.4
|
DHX15
|
DEAH (Asp-Glu-Ala-His) box helicase 15 |
| chrX_+_101380642 | 1.97 |
ENST00000372780.1
ENST00000329035.2 |
TCEAL2
|
transcription elongation factor A (SII)-like 2 |
| chr11_+_64863587 | 1.96 |
ENST00000530773.1
ENST00000279281.3 ENST00000529180.1 |
VPS51
|
vacuolar protein sorting 51 homolog (S. cerevisiae) |
| chr4_+_83351715 | 1.95 |
ENST00000273920.3
|
ENOPH1
|
enolase-phosphatase 1 |
| chr20_+_35201993 | 1.94 |
ENST00000373872.4
|
TGIF2
|
TGFB-induced factor homeobox 2 |
| chr11_+_46354455 | 1.94 |
ENST00000343674.6
|
DGKZ
|
diacylglycerol kinase, zeta |
| chr6_-_90529418 | 1.91 |
ENST00000439638.1
ENST00000369393.3 ENST00000428876.1 |
MDN1
|
MDN1, midasin homolog (yeast) |
| chr17_+_73257742 | 1.91 |
ENST00000579761.1
ENST00000245539.6 |
MRPS7
|
mitochondrial ribosomal protein S7 |
| chr4_+_83351791 | 1.90 |
ENST00000509635.1
|
ENOPH1
|
enolase-phosphatase 1 |
| chr8_-_145515055 | 1.89 |
ENST00000526552.1
ENST00000529231.1 ENST00000307404.5 |
BOP1
|
block of proliferation 1 |
| chr15_-_58357932 | 1.89 |
ENST00000347587.3
|
ALDH1A2
|
aldehyde dehydrogenase 1 family, member A2 |
| chr19_+_49622646 | 1.86 |
ENST00000334186.4
|
PPFIA3
|
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| chr6_-_13814663 | 1.86 |
ENST00000359495.2
ENST00000379170.4 |
MCUR1
|
mitochondrial calcium uniporter regulator 1 |
| chr1_+_111682827 | 1.84 |
ENST00000357172.4
|
CEPT1
|
choline/ethanolamine phosphotransferase 1 |
| chr11_+_64004888 | 1.83 |
ENST00000541681.1
|
VEGFB
|
vascular endothelial growth factor B |
| chr9_+_132427883 | 1.83 |
ENST00000372469.4
|
PRRX2
|
paired related homeobox 2 |
| chr3_-_47619623 | 1.82 |
ENST00000456150.1
|
CSPG5
|
chondroitin sulfate proteoglycan 5 (neuroglycan C) |
| chr16_+_85646891 | 1.81 |
ENST00000393243.1
|
GSE1
|
Gse1 coiled-coil protein |
| chr1_-_23670752 | 1.80 |
ENST00000302271.6
ENST00000426846.2 ENST00000427764.2 ENST00000606561.1 ENST00000374616.3 |
HNRNPR
|
heterogeneous nuclear ribonucleoprotein R |
| chr3_-_13009168 | 1.80 |
ENST00000273221.4
|
IQSEC1
|
IQ motif and Sec7 domain 1 |
| chr12_-_93835665 | 1.80 |
ENST00000552442.1
ENST00000550657.1 |
UBE2N
|
ubiquitin-conjugating enzyme E2N |
| chr6_+_157802165 | 1.79 |
ENST00000414563.2
ENST00000359775.5 |
ZDHHC14
|
zinc finger, DHHC-type containing 14 |
| chr1_+_165797024 | 1.79 |
ENST00000372212.4
|
UCK2
|
uridine-cytidine kinase 2 |
| chr21_-_38445443 | 1.76 |
ENST00000360525.4
|
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chr22_+_50247449 | 1.76 |
ENST00000216268.5
|
ZBED4
|
zinc finger, BED-type containing 4 |
| chr21_-_44495964 | 1.76 |
ENST00000398168.1
ENST00000398165.3 |
CBS
|
cystathionine-beta-synthase |
| chr1_-_45805752 | 1.73 |
ENST00000354383.6
ENST00000355498.2 ENST00000372100.5 ENST00000531105.1 |
MUTYH
|
mutY homolog |
| chr11_+_1968508 | 1.73 |
ENST00000397298.3
ENST00000381519.1 ENST00000397297.3 ENST00000381514.3 ENST00000397294.3 |
MRPL23
|
mitochondrial ribosomal protein L23 |
| chr8_+_85097110 | 1.72 |
ENST00000517638.1
ENST00000522647.1 |
RALYL
|
RALY RNA binding protein-like |
| chr4_+_17812525 | 1.72 |
ENST00000251496.2
|
NCAPG
|
non-SMC condensin I complex, subunit G |
| chr3_-_121553830 | 1.71 |
ENST00000498104.1
ENST00000460108.1 ENST00000349820.6 ENST00000462442.1 ENST00000310864.6 |
IQCB1
|
IQ motif containing B1 |
| chr19_+_8509842 | 1.70 |
ENST00000325495.4
ENST00000600092.1 ENST00000594907.1 ENST00000596984.1 ENST00000601645.1 |
HNRNPM
|
heterogeneous nuclear ribonucleoprotein M |
| chr19_-_8386238 | 1.70 |
ENST00000301457.2
|
NDUFA7
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa |
| chr17_+_8191815 | 1.69 |
ENST00000226105.6
ENST00000407006.4 ENST00000580434.1 ENST00000439238.3 |
RANGRF
|
RAN guanine nucleotide release factor |
| chr16_+_85646763 | 1.69 |
ENST00000411612.1
ENST00000253458.7 |
GSE1
|
Gse1 coiled-coil protein |
| chr21_-_10990830 | 1.68 |
ENST00000361285.4
ENST00000342420.5 ENST00000328758.5 |
TPTE
|
transmembrane phosphatase with tensin homology |
| chr7_+_106685079 | 1.67 |
ENST00000265717.4
|
PRKAR2B
|
protein kinase, cAMP-dependent, regulatory, type II, beta |
| chr3_-_10749696 | 1.67 |
ENST00000397077.1
|
ATP2B2
|
ATPase, Ca++ transporting, plasma membrane 2 |
| chr22_+_32340481 | 1.66 |
ENST00000397492.1
|
YWHAH
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| chr3_+_49058444 | 1.66 |
ENST00000326925.6
ENST00000395458.2 |
NDUFAF3
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 |
| chr2_-_136743039 | 1.65 |
ENST00000537273.1
|
DARS
|
aspartyl-tRNA synthetase |
| chr20_+_11871433 | 1.64 |
ENST00000399006.2
ENST00000405977.1 |
BTBD3
|
BTB (POZ) domain containing 3 |
| chr5_-_7869108 | 1.63 |
ENST00000264669.5
ENST00000507572.1 ENST00000504695.1 |
FASTKD3
|
FAST kinase domains 3 |
| chr21_-_10990888 | 1.63 |
ENST00000298232.7
|
TPTE
|
transmembrane phosphatase with tensin homology |
| chr3_-_133380731 | 1.63 |
ENST00000260810.5
|
TOPBP1
|
topoisomerase (DNA) II binding protein 1 |
| chr1_-_23670813 | 1.62 |
ENST00000374612.1
|
HNRNPR
|
heterogeneous nuclear ribonucleoprotein R |
| chr1_-_92949505 | 1.62 |
ENST00000370332.1
|
GFI1
|
growth factor independent 1 transcription repressor |
| chr22_+_29664248 | 1.62 |
ENST00000406548.1
ENST00000437155.2 ENST00000415761.1 ENST00000331029.7 |
EWSR1
|
EWS RNA-binding protein 1 |
| chr9_-_111696224 | 1.62 |
ENST00000537196.1
|
IKBKAP
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| chr20_+_11871371 | 1.59 |
ENST00000254977.3
|
BTBD3
|
BTB (POZ) domain containing 3 |
| chr7_+_99775366 | 1.58 |
ENST00000394018.2
ENST00000416412.1 |
STAG3
|
stromal antigen 3 |
| chr13_-_41635512 | 1.58 |
ENST00000405737.2
|
ELF1
|
E74-like factor 1 (ets domain transcription factor) |
| chr19_+_50353944 | 1.57 |
ENST00000594151.1
ENST00000600603.1 ENST00000601638.1 ENST00000221557.9 |
PTOV1
|
prostate tumor overexpressed 1 |
| chr6_-_125623046 | 1.56 |
ENST00000608295.1
ENST00000398153.2 ENST00000608284.1 ENST00000368377.4 |
HDDC2
|
HD domain containing 2 |
| chr5_-_78809950 | 1.55 |
ENST00000334082.6
|
HOMER1
|
homer homolog 1 (Drosophila) |
| chr7_+_102073966 | 1.55 |
ENST00000495936.1
ENST00000356387.2 ENST00000478730.2 ENST00000468241.1 ENST00000403646.3 |
ORAI2
|
ORAI calcium release-activated calcium modulator 2 |
| chr14_-_105635090 | 1.54 |
ENST00000331782.3
ENST00000347004.2 |
JAG2
|
jagged 2 |
| chr10_-_121302195 | 1.54 |
ENST00000369103.2
|
RGS10
|
regulator of G-protein signaling 10 |
| chr11_-_134093827 | 1.53 |
ENST00000534548.2
|
NCAPD3
|
non-SMC condensin II complex, subunit D3 |
| chr16_+_11038345 | 1.52 |
ENST00000409790.1
|
CLEC16A
|
C-type lectin domain family 16, member A |
| chr7_+_73588665 | 1.52 |
ENST00000353999.6
|
EIF4H
|
eukaryotic translation initiation factor 4H |
| chr22_+_20105259 | 1.52 |
ENST00000416427.1
ENST00000421656.1 ENST00000423859.1 ENST00000418705.2 |
RANBP1
|
RAN binding protein 1 |
| chr11_+_86748863 | 1.51 |
ENST00000340353.7
|
TMEM135
|
transmembrane protein 135 |
| chr15_-_90645679 | 1.50 |
ENST00000539790.1
ENST00000559482.1 ENST00000330062.3 |
IDH2
|
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| chr13_-_39612176 | 1.50 |
ENST00000352251.3
ENST00000350125.3 |
PROSER1
|
proline and serine rich 1 |
| chr2_+_232575128 | 1.50 |
ENST00000412128.1
|
PTMA
|
prothymosin, alpha |
| chr3_+_8775466 | 1.48 |
ENST00000343849.2
ENST00000397368.2 |
CAV3
|
caveolin 3 |
| chr2_-_70529180 | 1.47 |
ENST00000450256.1
ENST00000037869.3 |
FAM136A
|
family with sequence similarity 136, member A |
| chr14_+_50234309 | 1.47 |
ENST00000298307.5
|
KLHDC2
|
kelch domain containing 2 |
| chr1_-_154531095 | 1.46 |
ENST00000292211.4
|
UBE2Q1
|
ubiquitin-conjugating enzyme E2Q family member 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HES1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 12.3 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 4.0 | 11.9 | GO:0019242 | methylglyoxal biosynthetic process(GO:0019242) |
| 3.2 | 9.7 | GO:0046102 | inosine metabolic process(GO:0046102) |
| 3.2 | 9.6 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 2.9 | 2.9 | GO:0070670 | response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353) |
| 2.6 | 7.9 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 1.8 | 5.4 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
| 1.7 | 5.0 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 1.5 | 7.4 | GO:0034971 | regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R17 methylation(GO:0034971) |
| 1.5 | 11.8 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 1.5 | 4.4 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 1.4 | 4.1 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 1.2 | 3.7 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 1.2 | 4.8 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 1.1 | 3.4 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 1.1 | 8.9 | GO:0002326 | B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152) |
| 1.1 | 7.6 | GO:0045007 | depurination(GO:0045007) |
| 1.1 | 4.2 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 1.1 | 3.2 | GO:0070602 | regulation of centromeric sister chromatid cohesion(GO:0070602) |
| 1.0 | 3.1 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.9 | 2.7 | GO:0043105 | regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105) |
| 0.9 | 8.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.9 | 3.5 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.8 | 2.5 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 0.8 | 2.5 | GO:1902499 | positive regulation of protein autoubiquitination(GO:1902499) |
| 0.8 | 4.2 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.7 | 2.2 | GO:0070632 | spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790) |
| 0.7 | 2.1 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
| 0.7 | 2.8 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.7 | 2.1 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.7 | 2.8 | GO:2000426 | plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.7 | 2.1 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 0.7 | 2.0 | GO:0048203 | vesicle targeting, trans-Golgi to endosome(GO:0048203) |
| 0.7 | 5.4 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.6 | 1.8 | GO:0035604 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915) |
| 0.6 | 2.3 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.5 | 2.2 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.5 | 1.6 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 0.5 | 3.2 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.5 | 1.6 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.5 | 24.1 | GO:0006735 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.5 | 1.5 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.5 | 2.9 | GO:0044211 | CTP salvage(GO:0044211) |
| 0.5 | 1.9 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.5 | 1.9 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.5 | 1.4 | GO:0034227 | tRNA thio-modification(GO:0034227) |
| 0.5 | 1.8 | GO:0019086 | late viral transcription(GO:0019086) |
| 0.5 | 14.3 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
| 0.5 | 2.3 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) |
| 0.5 | 2.3 | GO:2000771 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 0.4 | 3.1 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.4 | 2.2 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 0.4 | 4.0 | GO:1900825 | regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825) |
| 0.4 | 2.2 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 0.4 | 3.5 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.4 | 3.9 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.4 | 2.1 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.4 | 1.6 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 0.4 | 18.4 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.4 | 2.8 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.4 | 1.2 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.4 | 3.1 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 0.4 | 1.5 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.4 | 1.5 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 0.4 | 0.4 | GO:0003419 | growth plate cartilage chondrocyte proliferation(GO:0003419) |
| 0.4 | 1.1 | GO:0100009 | regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 0.4 | 3.0 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.4 | 5.6 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.4 | 2.2 | GO:0042780 | tRNA 3'-end processing(GO:0042780) |
| 0.4 | 1.1 | GO:0008355 | olfactory learning(GO:0008355) |
| 0.4 | 1.1 | GO:2000705 | dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705) |
| 0.4 | 1.5 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.4 | 4.2 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.3 | 1.3 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 0.3 | 1.3 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.3 | 1.7 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.3 | 2.3 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.3 | 1.6 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.3 | 3.9 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.3 | 2.2 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126) |
| 0.3 | 2.5 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.3 | 1.2 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.3 | 1.2 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.3 | 2.7 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.3 | 1.2 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.3 | 2.7 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.3 | 7.4 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.3 | 0.9 | GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
| 0.3 | 2.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.3 | 1.1 | GO:0001743 | optic placode formation(GO:0001743) axial mesoderm morphogenesis(GO:0048319) |
| 0.3 | 0.8 | GO:1904530 | negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617) |
| 0.3 | 7.0 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.3 | 1.1 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 0.3 | 1.1 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.3 | 2.1 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 0.3 | 1.6 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.3 | 1.8 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.3 | 2.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.3 | 0.8 | GO:0002071 | glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) |
| 0.2 | 0.7 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.2 | 0.2 | GO:0045976 | negative regulation of mitotic cell cycle, embryonic(GO:0045976) |
| 0.2 | 2.1 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.2 | 5.0 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.2 | 1.6 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.2 | 4.0 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.2 | 0.7 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.2 | 3.7 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.2 | 1.7 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.2 | 6.5 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.2 | 2.1 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.2 | 2.1 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.2 | 0.4 | GO:0072367 | regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) |
| 0.2 | 0.6 | GO:0035623 | regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623) |
| 0.2 | 0.6 | GO:0098502 | DNA dephosphorylation(GO:0098502) |
| 0.2 | 1.8 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.2 | 1.4 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.2 | 1.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.2 | 0.6 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.2 | 4.7 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.2 | 1.9 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.2 | 0.6 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.2 | 1.1 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.2 | 0.9 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.2 | 1.4 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.2 | 0.5 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.2 | 0.7 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.2 | 0.5 | GO:0021586 | pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 0.2 | 0.5 | GO:0033341 | regulation of collagen binding(GO:0033341) |
| 0.2 | 1.3 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.2 | 1.0 | GO:0003418 | growth plate cartilage chondrocyte differentiation(GO:0003418) |
| 0.2 | 4.4 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.2 | 1.8 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 0.2 | 0.3 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 0.2 | 1.5 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.2 | 0.3 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 0.2 | 1.4 | GO:1902415 | regulation of mRNA binding(GO:1902415) |
| 0.2 | 1.6 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.2 | 1.1 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.2 | 1.9 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.2 | 2.8 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.2 | 2.9 | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166) |
| 0.2 | 0.8 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.1 | 1.8 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 4.2 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.1 | 0.7 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.1 | 0.6 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.1 | 1.5 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
| 0.1 | 1.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.1 | 0.4 | GO:1902490 | regulation of sperm capacitation(GO:1902490) |
| 0.1 | 0.7 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 0.1 | 1.1 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.1 | 0.5 | GO:1904628 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.1 | 2.1 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.1 | 1.4 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.1 | 1.5 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.1 | 0.4 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.1 | 0.6 | GO:1901907 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.1 | 1.1 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.1 | 7.0 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.1 | 0.2 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.1 | 4.3 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.1 | 4.9 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.7 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.1 | 0.8 | GO:0036289 | peptidyl-serine autophosphorylation(GO:0036289) |
| 0.1 | 0.7 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.1 | 0.7 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
| 0.1 | 0.6 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.1 | 14.4 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 0.6 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.1 | 0.7 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 0.1 | 0.9 | GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091) |
| 0.1 | 2.4 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.1 | 0.4 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) |
| 0.1 | 1.5 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.1 | 1.4 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 0.1 | 1.3 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 0.1 | 3.5 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 4.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.1 | 0.3 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
| 0.1 | 0.8 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.1 | 1.5 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.1 | 1.8 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 0.7 | GO:0032057 | negative regulation of translational initiation in response to stress(GO:0032057) |
| 0.1 | 0.3 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.1 | 6.0 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.1 | 0.5 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.1 | 0.1 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 0.1 | 1.1 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.1 | 1.8 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.1 | 1.5 | GO:1901663 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.1 | 0.7 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 0.1 | 1.1 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 0.6 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.1 | 1.0 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.1 | 0.7 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
| 0.1 | 0.4 | GO:0009181 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 0.1 | 2.9 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 0.2 | GO:0071287 | phytoalexin metabolic process(GO:0052314) cellular response to manganese ion(GO:0071287) |
| 0.1 | 1.3 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.1 | 1.4 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.1 | 0.7 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.1 | 0.9 | GO:0042090 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.1 | 0.5 | GO:1903748 | negative regulation of establishment of protein localization to mitochondrion(GO:1903748) |
| 0.1 | 0.4 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.1 | 1.6 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.1 | 0.3 | GO:2000410 | regulation of thymocyte migration(GO:2000410) |
| 0.1 | 1.8 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 0.8 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.1 | 1.2 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.1 | 1.6 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.1 | 0.6 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.1 | 1.6 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) |
| 0.1 | 0.1 | GO:1903862 | positive regulation of oxidative phosphorylation(GO:1903862) |
| 0.1 | 1.2 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 0.3 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.1 | 0.2 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.1 | 1.3 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.1 | 0.2 | GO:2000724 | nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724) |
| 0.1 | 2.4 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.1 | 0.8 | GO:0060312 | regulation of blood vessel remodeling(GO:0060312) |
| 0.1 | 1.5 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.1 | 0.4 | GO:0072364 | regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364) |
| 0.1 | 0.2 | GO:2000275 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) regulation of oxidative phosphorylation uncoupler activity(GO:2000275) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) |
| 0.1 | 0.4 | GO:0014050 | negative regulation of glutamate secretion(GO:0014050) negative regulation of serotonin secretion(GO:0014063) |
| 0.1 | 1.7 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.1 | 0.5 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.1 | 0.5 | GO:0009886 | post-embryonic morphogenesis(GO:0009886) |
| 0.1 | 0.6 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.1 | 2.8 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.1 | 0.2 | GO:0090240 | positive regulation of histone H4 acetylation(GO:0090240) |
| 0.1 | 1.6 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.1 | 3.2 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.1 | 4.0 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.1 | 0.6 | GO:0046036 | UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051) |
| 0.1 | 0.9 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.1 | 0.6 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.1 | 0.7 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.1 | 0.6 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.1 | 0.4 | GO:0048105 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) |
| 0.1 | 4.0 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.1 | 0.3 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.1 | 1.4 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.1 | 1.4 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.1 | 0.3 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 2.8 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.4 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 0.0 | 0.7 | GO:0051683 | establishment of Golgi localization(GO:0051683) Golgi reassembly(GO:0090168) |
| 0.0 | 0.6 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.0 | 1.5 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 1.2 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.0 | 0.5 | GO:1904779 | regulation of protein localization to centrosome(GO:1904779) |
| 0.0 | 0.3 | GO:0071502 | cellular response to temperature stimulus(GO:0071502) |
| 0.0 | 0.5 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.0 | 1.3 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
| 0.0 | 0.3 | GO:0033578 | protein glycosylation in Golgi(GO:0033578) |
| 0.0 | 0.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.0 | 0.3 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 1.0 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.8 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.0 | 0.3 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.0 | 0.3 | GO:0015791 | polyol transport(GO:0015791) |
| 0.0 | 0.4 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 0.0 | 2.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 1.4 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 0.1 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 0.0 | 0.8 | GO:0043949 | regulation of cAMP-mediated signaling(GO:0043949) |
| 0.0 | 0.9 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.0 | 0.5 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.0 | 0.6 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.0 | 0.3 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.0 | 0.9 | GO:0060441 | epithelial tube branching involved in lung morphogenesis(GO:0060441) |
| 0.0 | 0.6 | GO:0042749 | regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
| 0.0 | 0.2 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.0 | 0.3 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.0 | 1.2 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 0.0 | 3.3 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 0.0 | 2.1 | GO:0045453 | bone resorption(GO:0045453) |
| 0.0 | 0.2 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.0 | 0.2 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.0 | 10.4 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.0 | 0.5 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.0 | 0.3 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.0 | 0.2 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.0 | 0.2 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.0 | 6.3 | GO:0006364 | rRNA processing(GO:0006364) |
| 0.0 | 0.4 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) regulation of DNA methylation(GO:0044030) |
| 0.0 | 0.7 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.0 | 1.0 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 3.2 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.9 | GO:0006260 | DNA replication(GO:0006260) |
| 0.0 | 0.1 | GO:1902268 | polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.0 | 0.4 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.0 | 0.2 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.0 | 0.9 | GO:0007140 | male meiosis(GO:0007140) |
| 0.0 | 0.1 | GO:1901374 | acetate ester transport(GO:1901374) |
| 0.0 | 1.6 | GO:0070126 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 0.0 | 0.3 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.0 | 0.5 | GO:0043065 | positive regulation of apoptotic process(GO:0043065) |
| 0.0 | 0.1 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.0 | 0.2 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
| 0.0 | 2.0 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.0 | 0.8 | GO:0009409 | response to cold(GO:0009409) |
| 0.0 | 0.1 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.0 | 0.4 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 0.2 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.4 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 1.8 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 0.2 | GO:1900151 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
| 0.0 | 0.7 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.2 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.0 | 0.7 | GO:0033137 | negative regulation of peptidyl-serine phosphorylation(GO:0033137) |
| 0.0 | 1.5 | GO:0007041 | lysosomal transport(GO:0007041) |
| 0.0 | 0.5 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.1 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 0.0 | 0.4 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.0 | 0.1 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.0 | 0.7 | GO:0010830 | regulation of myotube differentiation(GO:0010830) |
| 0.0 | 0.9 | GO:0051289 | protein homotetramerization(GO:0051289) |
| 0.0 | 0.1 | GO:0042355 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.0 | 3.1 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 0.5 | GO:0051480 | regulation of cytosolic calcium ion concentration(GO:0051480) |
| 0.0 | 0.2 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.1 | GO:0051189 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
| 0.0 | 0.1 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.0 | 0.5 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.2 | GO:1902229 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) |
| 0.0 | 0.6 | GO:0002548 | monocyte chemotaxis(GO:0002548) |
| 0.0 | 0.7 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 1.0 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 0.0 | 1.1 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.0 | 0.6 | GO:0035722 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 21.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 1.0 | 18.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 1.0 | 3.0 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.9 | 3.7 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.9 | 22.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.8 | 2.3 | GO:0097134 | cyclin E1-CDK2 complex(GO:0097134) |
| 0.7 | 2.2 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
| 0.6 | 2.6 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.6 | 8.4 | GO:0042555 | MCM complex(GO:0042555) |
| 0.6 | 1.8 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.6 | 2.4 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.6 | 2.9 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.5 | 2.0 | GO:0000811 | GINS complex(GO:0000811) |
| 0.5 | 2.0 | GO:1990745 | EARP complex(GO:1990745) |
| 0.5 | 2.3 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.5 | 1.8 | GO:0038038 | G-protein coupled receptor homodimeric complex(GO:0038038) |
| 0.4 | 0.9 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.4 | 2.5 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.4 | 2.0 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.4 | 2.7 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.4 | 1.5 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 0.3 | 3.8 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.3 | 1.9 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.3 | 4.7 | GO:0001741 | XY body(GO:0001741) |
| 0.3 | 2.1 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.3 | 1.2 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.3 | 1.7 | GO:0000796 | condensin complex(GO:0000796) |
| 0.3 | 8.7 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.3 | 1.4 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.3 | 1.1 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.3 | 1.1 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.3 | 1.6 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 0.2 | 4.9 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.2 | 4.2 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.2 | 12.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.2 | 1.1 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.2 | 1.1 | GO:1902555 | endoribonuclease complex(GO:1902555) |
| 0.2 | 1.7 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.2 | 5.5 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.2 | 0.6 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.2 | 3.5 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.2 | 12.9 | GO:0015030 | Cajal body(GO:0015030) |
| 0.2 | 3.5 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.2 | 1.6 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.2 | 2.6 | GO:0090543 | Flemming body(GO:0090543) |
| 0.2 | 1.8 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.2 | 3.0 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.2 | 1.8 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.2 | 0.3 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.2 | 2.1 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 4.0 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.1 | 3.1 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 2.2 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 1.1 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 3.0 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 0.1 | 4.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 1.6 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.1 | 0.9 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.1 | 3.2 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 2.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 0.5 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.1 | 0.4 | GO:0016342 | catenin complex(GO:0016342) |
| 0.1 | 5.7 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 0.4 | GO:0060187 | cell pole(GO:0060187) |
| 0.1 | 11.5 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.1 | 3.2 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.1 | 1.4 | GO:0098574 | cytoplasmic side of lysosomal membrane(GO:0098574) |
| 0.1 | 2.5 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 2.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 0.3 | GO:1903349 | omegasome membrane(GO:1903349) |
| 0.1 | 2.7 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 0.7 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.1 | 1.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 2.2 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 1.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.1 | 1.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.1 | 0.4 | GO:0000791 | euchromatin(GO:0000791) |
| 0.1 | 0.5 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.1 | 0.7 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.1 | 0.6 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.1 | 3.6 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.1 | 2.1 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 0.7 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.1 | 3.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 6.5 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.1 | 0.2 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.1 | 7.0 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 1.5 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.1 | 1.3 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.1 | 2.3 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 2.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 0.5 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.1 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.1 | 0.4 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.1 | 0.7 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 0.6 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.1 | 8.9 | GO:0043679 | axon terminus(GO:0043679) |
| 0.1 | 3.0 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 4.8 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.1 | 0.7 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 1.4 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 1.7 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 3.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 0.9 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 1.2 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 2.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 0.4 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.1 | 2.8 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 0.1 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.1 | 1.5 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 3.3 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 0.6 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 6.6 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.0 | 1.4 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.7 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 0.1 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.0 | 0.7 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
| 0.0 | 0.4 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 2.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 2.3 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.9 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.3 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 2.6 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.6 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 1.7 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 5.1 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 3.2 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.0 | 1.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 3.4 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 0.2 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 0.5 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.1 | GO:0035061 | Smc5-Smc6 complex(GO:0030915) interchromatin granule(GO:0035061) |
| 0.0 | 0.1 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.0 | 11.7 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 0.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.0 | 8.6 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 1.6 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 1.3 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.3 | GO:0043186 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.0 | 0.4 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 7.2 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 1.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 1.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 2.2 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 2.2 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.7 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 1.2 | GO:0005813 | centrosome(GO:0005813) |
| 0.0 | 0.4 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.6 | GO:0016460 | myosin II complex(GO:0016460) |
| 0.0 | 0.4 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 2.9 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 0.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 1.8 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 8.1 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 1.8 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 0.5 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 0.1 | GO:0000439 | core TFIIH complex(GO:0000439) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 12.3 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 4.0 | 11.9 | GO:0004347 | glucose-6-phosphate isomerase activity(GO:0004347) |
| 3.6 | 21.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 1.9 | 7.6 | GO:0032408 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 1.8 | 5.4 | GO:0004122 | cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
| 1.8 | 8.9 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 1.5 | 4.6 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 1.5 | 4.4 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 1.3 | 14.5 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 1.3 | 5.0 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 1.2 | 8.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 1.1 | 9.6 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 1.0 | 4.2 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 1.0 | 18.3 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 1.0 | 3.0 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.9 | 7.6 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.9 | 2.7 | GO:0044549 | GTP cyclohydrolase binding(GO:0044549) |
| 0.9 | 2.6 | GO:0016418 | S-acetyltransferase activity(GO:0016418) |
| 0.8 | 5.9 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.8 | 8.1 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.7 | 2.2 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 0.7 | 2.1 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 0.7 | 2.1 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.6 | 3.1 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.6 | 3.5 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.5 | 1.6 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.5 | 1.1 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.5 | 3.1 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.5 | 1.6 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.5 | 2.0 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
| 0.5 | 1.5 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.5 | 3.5 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.5 | 1.0 | GO:0008173 | RNA methyltransferase activity(GO:0008173) |
| 0.5 | 2.8 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.5 | 2.8 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.5 | 1.8 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307) |
| 0.4 | 2.9 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.4 | 1.2 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
| 0.4 | 2.4 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.4 | 1.2 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
| 0.4 | 3.5 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.4 | 1.5 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 0.4 | 1.5 | GO:0034057 | RNA strand-exchange activity(GO:0034057) |
| 0.4 | 2.3 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.4 | 1.1 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.4 | 1.1 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.4 | 1.4 | GO:0051733 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.3 | 2.7 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.3 | 2.0 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.3 | 0.9 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.3 | 2.4 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.3 | 1.1 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.3 | 7.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.3 | 3.1 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.3 | 2.3 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 0.3 | 2.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.3 | 3.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.2 | 2.2 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.2 | 0.7 | GO:0003968 | RNA-directed RNA polymerase activity(GO:0003968) |
| 0.2 | 1.8 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.2 | 2.2 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.2 | 10.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.2 | 9.8 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.2 | 1.0 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.2 | 4.3 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.2 | 1.1 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.2 | 0.6 | GO:0033867 | Fas-activated serine/threonine kinase activity(GO:0033867) |
| 0.2 | 1.5 | GO:0071253 | connexin binding(GO:0071253) |
| 0.2 | 0.9 | GO:0017161 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 0.2 | 3.2 | GO:0005522 | profilin binding(GO:0005522) |
| 0.2 | 7.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.2 | 1.8 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.2 | 0.5 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.2 | 0.5 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.2 | 1.2 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.2 | 1.2 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.2 | 3.2 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.2 | 0.5 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.2 | 0.8 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.2 | 4.8 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 2.1 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.2 | 0.6 | GO:0016499 | orexin receptor activity(GO:0016499) |
| 0.2 | 0.8 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.2 | 1.6 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.2 | 1.0 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 3.9 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.2 | 2.9 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.1 | 0.4 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.1 | 1.1 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.1 | 2.9 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.1 | 1.5 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.1 | 1.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 0.5 | GO:0005151 | interleukin-1, Type II receptor binding(GO:0005151) |
| 0.1 | 0.9 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.1 | 0.6 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.1 | 0.6 | GO:0052845 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.1 | 1.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 6.6 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.1 | 5.2 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 1.0 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.1 | 1.4 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.1 | 0.6 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.1 | 0.7 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.1 | 0.9 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.1 | 1.2 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
| 0.1 | 4.4 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 3.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.1 | 1.6 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 1.3 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.1 | 3.2 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 2.5 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 1.1 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 1.3 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.1 | 0.6 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.1 | 1.4 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
| 0.1 | 0.3 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.1 | 1.4 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.1 | 1.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 1.0 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 2.4 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 0.1 | 1.9 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 0.5 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.1 | 1.0 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.1 | 4.7 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.1 | 2.0 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 1.1 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 1.1 | GO:0022851 | benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851) |
| 0.1 | 6.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 2.2 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.1 | 0.8 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.1 | 0.6 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.1 | 0.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 0.4 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.1 | 0.2 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.1 | 2.2 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 1.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.1 | 1.8 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 0.7 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 1.0 | GO:0008603 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 0.7 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 0.2 | GO:0017082 | mineralocorticoid receptor activity(GO:0017082) |
| 0.1 | 0.1 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.1 | 2.4 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 1.4 | GO:0015278 | calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604) |
| 0.1 | 2.7 | GO:0008408 | 3'-5' exonuclease activity(GO:0008408) |
| 0.1 | 0.7 | GO:0031386 | protein tag(GO:0031386) |
| 0.1 | 2.1 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.1 | 1.1 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.2 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 0.1 | 0.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 3.0 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.1 | 1.2 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 1.5 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 1.0 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 2.3 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.1 | 1.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 0.8 | GO:0005283 | sodium:amino acid symporter activity(GO:0005283) |
| 0.1 | 0.7 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 2.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 1.4 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 0.2 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.1 | 6.2 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 1.0 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 0.2 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
| 0.1 | 1.6 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.7 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 0.2 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 0.1 | 0.3 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 0.3 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.2 | GO:0034617 | tetrahydrobiopterin binding(GO:0034617) |
| 0.0 | 0.8 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 1.1 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
| 0.0 | 0.4 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 4.6 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.0 | 0.1 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
| 0.0 | 0.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 0.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.3 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.0 | 1.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 1.6 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.0 | 0.3 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
| 0.0 | 1.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 7.0 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.0 | 0.4 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.4 | GO:0004645 | phosphorylase activity(GO:0004645) |
| 0.0 | 0.1 | GO:0052725 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 0.0 | 1.5 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.2 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.0 | 0.8 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 0.2 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.0 | 0.5 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.1 | GO:0005333 | norepinephrine transmembrane transporter activity(GO:0005333) |
| 0.0 | 0.9 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 2.6 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 2.0 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.0 | 1.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.3 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.0 | 0.4 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.0 | 0.8 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.1 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 1.0 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.3 | GO:0016409 | palmitoyltransferase activity(GO:0016409) |
| 0.0 | 0.4 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 1.6 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 5.0 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.1 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
| 0.0 | 1.5 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 3.0 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.2 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 4.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.1 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.0 | 1.3 | GO:0016740 | transferase activity(GO:0016740) |
| 0.0 | 0.1 | GO:0019828 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.0 | 8.3 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.4 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.0 | 0.7 | GO:0016879 | ligase activity, forming carbon-nitrogen bonds(GO:0016879) |
| 0.0 | 0.1 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.4 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.0 | 0.2 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.5 | GO:0019902 | phosphatase binding(GO:0019902) |
| 0.0 | 1.1 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.0 | 0.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.9 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.6 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.0 | 0.8 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.1 | GO:0030151 | molybdenum ion binding(GO:0030151) |
| 0.0 | 0.0 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.0 | 1.4 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 1.1 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 0.1 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.0 | 0.2 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.0 | 0.1 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.0 | 0.4 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.7 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.2 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.0 | 0.7 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.0 | 1.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.6 | GO:0008146 | sulfotransferase activity(GO:0008146) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.1 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.3 | 13.3 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.2 | 2.6 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.2 | 2.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.2 | 14.3 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 7.8 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 2.7 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 8.4 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 6.5 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 5.0 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 3.6 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 1.1 | PID MYC PATHWAY | C-MYC pathway |
| 0.1 | 6.3 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 3.3 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 11.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 6.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 1.8 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 2.3 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 1.7 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 3.6 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 2.5 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 2.5 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 4.7 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 1.7 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 2.8 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.1 | 1.3 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 2.6 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 2.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 2.3 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.9 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 1.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 1.7 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.8 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 2.9 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.6 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 0.6 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.4 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 0.6 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 0.3 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 1.4 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.9 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 1.2 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.3 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.7 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 0.4 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 18.3 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.7 | 35.4 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.7 | 10.8 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.5 | 12.2 | REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| 0.4 | 6.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.4 | 9.0 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.3 | 2.7 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.3 | 7.5 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.3 | 4.8 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.3 | 3.2 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.3 | 2.9 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.3 | 1.8 | REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
| 0.2 | 2.2 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.2 | 1.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.2 | 5.7 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.2 | 4.8 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.2 | 4.2 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.2 | 3.7 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.2 | 5.0 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.2 | 3.4 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.2 | 4.6 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.2 | 1.4 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.2 | 2.8 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.2 | 14.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 2.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.2 | 7.5 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 2.1 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.1 | 1.5 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.1 | 1.8 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.1 | 0.6 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 1.8 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.1 | 1.9 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 2.3 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.1 | 4.7 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 1.3 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 5.2 | REACTOME TRNA AMINOACYLATION | Genes involved in tRNA Aminoacylation |
| 0.1 | 1.8 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 1.3 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 0.7 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.1 | 2.8 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 21.6 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 3.2 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.1 | 2.3 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.1 | 1.8 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 1.1 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 3.9 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.1 | 2.0 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 0.9 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 0.5 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 6.4 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 2.7 | REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | Genes involved in Glucagon signaling in metabolic regulation |
| 0.1 | 1.0 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.1 | 1.4 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 3.4 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 1.5 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 1.1 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.1 | 3.0 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.1 | 0.5 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 1.4 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.1 | 0.8 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 0.4 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.0 | 1.0 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.7 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 3.7 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.7 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.7 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.0 | 2.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.7 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.4 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 3.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.4 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.7 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 1.1 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 2.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 1.1 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 2.0 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 1.2 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 1.0 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.5 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.2 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.0 | 2.1 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.2 | REACTOME PROLONGED ERK ACTIVATION EVENTS | Genes involved in Prolonged ERK activation events |
| 0.0 | 3.4 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 1.4 | REACTOME GAB1 SIGNALOSOME | Genes involved in GAB1 signalosome |
| 0.0 | 0.6 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 1.0 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.1 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.5 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.1 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 0.4 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 0.9 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.2 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.2 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |