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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for HES1

Z-value: 0.20

Motif logo

Transcription factors associated with HES1

Gene Symbol Gene ID Gene Info
ENSG00000114315.3 hes family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES1hg19_v2_chr3_+_193853927_193853944-0.127.5e-02Click!

Activity profile of HES1 motif

Sorted Z-values of HES1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_7023491 13.21 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr3_-_138763734 9.00 ENST00000413199.1
ENST00000502927.2
proline rich 23C
chr19_-_1652575 8.86 ENST00000587235.1
ENST00000262965.5
transcription factor 3
chr12_+_7023735 8.42 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr20_-_43280325 7.55 ENST00000537820.1
adenosine deaminase
chr9_+_91926103 6.70 ENST00000314355.6
CDC28 protein kinase regulatory subunit 2
chr2_-_73511559 6.51 ENST00000521871.1
F-box protein 41
chr20_-_3154162 6.47 ENST00000360342.3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr1_-_32801825 6.13 ENST00000329421.7
MARCKS-like 1
chr5_+_156693091 6.11 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
cytoplasmic FMR1 interacting protein 2
chr16_+_2039946 5.91 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr5_+_156693159 5.73 ENST00000347377.6
cytoplasmic FMR1 interacting protein 2
chr3_+_184081137 5.63 ENST00000443489.1
polymerase (RNA) II (DNA directed) polypeptide H
chr7_-_99698338 5.49 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr7_-_148581251 5.36 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
enhancer of zeste homolog 2 (Drosophila)
chr3_+_184081175 5.27 ENST00000452961.1
ENST00000296223.3
polymerase (RNA) II (DNA directed) polypeptide H
chr17_-_3599696 5.18 ENST00000225328.5
purinergic receptor P2X, ligand-gated ion channel, 5
chr3_+_184081213 5.09 ENST00000429568.1
polymerase (RNA) II (DNA directed) polypeptide H
chr4_-_185655278 4.93 ENST00000281453.5
centromere protein U
chr3_-_47823298 4.70 ENST00000254480.5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr17_-_3599327 4.69 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr2_-_96811170 4.62 ENST00000288943.4
dual specificity phosphatase 2
chr17_-_3599492 4.61 ENST00000435558.1
ENST00000345901.3
purinergic receptor P2X, ligand-gated ion channel, 5
chr1_-_25291475 4.42 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr1_+_41445413 4.38 ENST00000541520.1
CTP synthase 1
chr15_+_89182178 4.33 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr7_-_148581360 4.29 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
enhancer of zeste homolog 2 (Drosophila)
chr2_-_10588630 4.23 ENST00000234111.4
ornithine decarboxylase 1
chr15_+_52311398 4.17 ENST00000261845.5
mitogen-activated protein kinase 6
chr19_+_34855874 4.13 ENST00000588991.2
glucose-6-phosphate isomerase
chr15_+_89182156 4.13 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr19_-_55919087 4.11 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
ubiquitin-conjugating enzyme E2S
chr17_-_57184260 4.01 ENST00000376149.3
ENST00000393066.3
tripartite motif containing 37
chr19_+_34855925 3.99 ENST00000590375.1
ENST00000356487.5
glucose-6-phosphate isomerase
chr17_-_57184064 3.94 ENST00000262294.7
tripartite motif containing 37
chr19_+_10982336 3.88 ENST00000344150.4
coactivator-associated arginine methyltransferase 1
chr14_+_100437780 3.87 ENST00000402714.2
Enah/Vasp-like
chr19_+_34856141 3.81 ENST00000586425.1
glucose-6-phosphate isomerase
chr15_+_89181974 3.79 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr21_-_44495919 3.69 ENST00000398158.1
cystathionine-beta-synthase
chr7_+_155089486 3.69 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
insulin induced gene 1
chr12_-_76478686 3.67 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr11_-_113746212 3.64 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
ubiquitin specific peptidase 28
chr19_+_10982189 3.53 ENST00000327064.4
ENST00000588947.1
coactivator-associated arginine methyltransferase 1
chr2_+_216176540 3.51 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr3_+_183415558 3.50 ENST00000305135.5
YEATS domain containing 2
chr17_-_3867585 3.47 ENST00000359983.3
ENST00000352011.3
ENST00000397043.3
ENST00000397041.3
ENST00000397035.3
ENST00000397039.1
ENST00000309890.7
ATPase, Ca++ transporting, ubiquitous
chr12_-_76478417 3.47 ENST00000552342.1
nucleosome assembly protein 1-like 1
chr1_+_91966656 3.46 ENST00000428239.1
ENST00000426137.1
cell division cycle 7
chr8_+_56014949 3.39 ENST00000327381.6
XK, Kell blood group complex subunit-related family, member 4
chr19_-_7936344 3.36 ENST00000599142.1
Protein FLJ22184
chr2_-_136633940 3.32 ENST00000264156.2
minichromosome maintenance complex component 6
chr1_-_53793725 3.26 ENST00000371454.2
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr11_-_113746277 3.21 ENST00000003302.4
ENST00000545540.1
ubiquitin specific peptidase 28
chr12_-_76478386 3.21 ENST00000535020.2
nucleosome assembly protein 1-like 1
chr9_-_131790464 3.18 ENST00000417224.1
ENST00000416629.1
ENST00000372559.1
SH3-domain GRB2-like endophilin B2
chr16_+_67596310 3.17 ENST00000264010.4
ENST00000401394.1
CCCTC-binding factor (zinc finger protein)
chr16_+_29817841 3.14 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr13_+_103249322 3.14 ENST00000376065.4
ENST00000376052.3
tripeptidyl peptidase II
chr12_-_117537240 3.13 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
tescalcin
chr9_-_101471479 3.01 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr4_+_57302297 3.00 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr12_-_49525175 2.94 ENST00000336023.5
ENST00000550367.1
ENST00000552984.1
ENST00000547476.1
tubulin, alpha 1b
chr15_-_44069741 2.94 ENST00000319359.3
elongation factor RNA polymerase II-like 3
chr3_-_148804275 2.84 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr18_-_77793891 2.84 ENST00000592957.1
ENST00000585474.1
thioredoxin-like 4A
chr22_-_37213045 2.84 ENST00000406910.2
ENST00000417718.2
parvalbumin
chr2_+_178077477 2.84 ENST00000411529.2
ENST00000435711.1
heterogeneous nuclear ribonucleoprotein A3
chr5_+_149546334 2.82 ENST00000231656.8
caudal type homeobox 1
chr20_+_55966444 2.80 ENST00000356208.5
ENST00000440234.2
RNA binding motif protein 38
chr13_-_31039375 2.78 ENST00000399494.1
high mobility group box 1
chr9_+_131451480 2.72 ENST00000322030.8
SET nuclear oncogene
chr1_+_28844778 2.72 ENST00000411533.1
regulator of chromosome condensation 1
chr20_+_35201857 2.71 ENST00000373874.2
TGFB-induced factor homeobox 2
chr5_+_61602055 2.69 ENST00000381103.2
kinesin heavy chain member 2A
chr18_+_12947981 2.69 ENST00000262124.11
SEH1-like (S. cerevisiae)
chr9_-_15510989 2.68 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PC4 and SFRS1 interacting protein 1
chr15_+_41056218 2.68 ENST00000260447.4
GTP cyclohydrolase I feedback regulator
chr12_+_131356582 2.65 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN, member RAS oncogene family
chrX_-_102319092 2.64 ENST00000372728.3
brain expressed, X-linked 1
chr12_-_125348448 2.62 ENST00000339570.5
scavenger receptor class B, member 1
chr1_-_46152174 2.59 ENST00000290795.3
ENST00000355105.3
GC-rich promoter binding protein 1-like 1
chr12_-_76478446 2.57 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
nucleosome assembly protein 1-like 1
chr11_-_46867780 2.56 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
cytoskeleton associated protein 5
chr1_+_6845384 2.55 ENST00000303635.7
calmodulin binding transcription activator 1
chr20_+_31407692 2.55 ENST00000375571.5
microtubule-associated protein, RP/EB family, member 1
chrX_-_48776292 2.52 ENST00000376509.4
pim-2 oncogene
chr14_+_105886150 2.51 ENST00000331320.7
ENST00000406191.1
metastasis associated 1
chr17_-_10101868 2.50 ENST00000432992.2
ENST00000540214.1
growth arrest-specific 7
chr1_-_101491319 2.49 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
diphthamide biosynthesis 5
chr15_+_84115868 2.48 ENST00000427482.2
SH3-domain GRB2-like 3
chr7_+_150065278 2.47 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr6_-_13711773 2.44 ENST00000011619.3
RAN binding protein 9
chr12_-_125348329 2.42 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
scavenger receptor class B, member 1
chr1_-_111743285 2.38 ENST00000357640.4
DENN/MADD domain containing 2D
chr5_+_6714718 2.37 ENST00000230859.6
ENST00000515721.1
PAP associated domain containing 7
chr10_+_3109695 2.36 ENST00000381125.4
phosphofructokinase, platelet
chr6_-_43197189 2.36 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr19_+_50887585 2.36 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
polymerase (DNA directed), delta 1, catalytic subunit
chr3_+_184080790 2.33 ENST00000430783.1
polymerase (RNA) II (DNA directed) polypeptide H
chr19_+_30302805 2.31 ENST00000262643.3
ENST00000575243.1
ENST00000357943.5
cyclin E1
chr1_-_45805667 2.29 ENST00000488731.2
ENST00000435155.1
mutY homolog
chr16_-_4466565 2.28 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16 readthrough
coronin 7
chr14_+_103243813 2.27 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TNF receptor-associated factor 3
chr3_+_23851928 2.26 ENST00000467766.1
ENST00000424381.1
ubiquitin-conjugating enzyme E2E 1
chr4_+_108911036 2.26 ENST00000505878.1
hydroxyacyl-CoA dehydrogenase
chr15_+_84116106 2.25 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr1_-_45805607 2.22 ENST00000372104.1
ENST00000448481.1
ENST00000483127.1
ENST00000528013.2
ENST00000456914.2
mutY homolog
chr19_-_48673552 2.21 ENST00000536218.1
ENST00000596549.1
ligase I, DNA, ATP-dependent
chr17_-_42402138 2.19 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
solute carrier family 25, member 39
chr14_-_51562745 2.19 ENST00000298355.3
tripartite motif containing 9
chr12_+_123319973 2.19 ENST00000253083.4
huntingtin interacting protein 1 related
chr14_+_20937538 2.18 ENST00000361505.5
ENST00000553591.1
purine nucleoside phosphorylase
chr1_-_41707778 2.16 ENST00000337495.5
ENST00000372597.1
ENST00000372596.1
sex comb on midleg homolog 1 (Drosophila)
chr1_+_225965518 2.14 ENST00000304786.7
ENST00000366839.4
ENST00000366838.1
signal recognition particle 9kDa
chr17_+_73257945 2.12 ENST00000579002.1
mitochondrial ribosomal protein S7
chr17_-_78450398 2.10 ENST00000306773.4
neuronal pentraxin I
chr2_+_232572361 2.10 ENST00000409321.1
prothymosin, alpha
chr1_+_220267429 2.10 ENST00000366922.1
ENST00000302637.5
isoleucyl-tRNA synthetase 2, mitochondrial
chr11_+_105948216 2.09 ENST00000278618.4
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr21_+_45527171 2.08 ENST00000291576.7
ENST00000456705.1
PWP2 periodic tryptophan protein homolog (yeast)
chr4_+_108910870 2.07 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
hydroxyacyl-CoA dehydrogenase
chr4_-_83351294 2.07 ENST00000502762.1
heterogeneous nuclear ribonucleoprotein D-like
chr18_+_77794446 2.05 ENST00000262197.7
ribosome binding factor A (putative)
chr22_+_32340447 2.04 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr9_+_37422663 2.03 ENST00000318158.6
ENST00000607784.1
glyoxylate reductase/hydroxypyruvate reductase
chr7_+_73703728 2.02 ENST00000361545.5
ENST00000223398.6
CAP-GLY domain containing linker protein 2
chr18_+_77794358 2.02 ENST00000306735.5
ribosome binding factor A (putative)
chr16_-_4466622 2.01 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
coronin 7
chr9_-_131790550 1.97 ENST00000372554.4
ENST00000372564.3
SH3-domain GRB2-like endophilin B2
chr4_-_24586140 1.97 ENST00000336812.4
DEAH (Asp-Glu-Ala-His) box helicase 15
chrX_+_101380642 1.97 ENST00000372780.1
ENST00000329035.2
transcription elongation factor A (SII)-like 2
chr11_+_64863587 1.96 ENST00000530773.1
ENST00000279281.3
ENST00000529180.1
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr4_+_83351715 1.95 ENST00000273920.3
enolase-phosphatase 1
chr20_+_35201993 1.94 ENST00000373872.4
TGFB-induced factor homeobox 2
chr11_+_46354455 1.94 ENST00000343674.6
diacylglycerol kinase, zeta
chr6_-_90529418 1.91 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1, midasin homolog (yeast)
chr17_+_73257742 1.91 ENST00000579761.1
ENST00000245539.6
mitochondrial ribosomal protein S7
chr4_+_83351791 1.90 ENST00000509635.1
enolase-phosphatase 1
chr8_-_145515055 1.89 ENST00000526552.1
ENST00000529231.1
ENST00000307404.5
block of proliferation 1
chr15_-_58357932 1.89 ENST00000347587.3
aldehyde dehydrogenase 1 family, member A2
chr19_+_49622646 1.86 ENST00000334186.4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr6_-_13814663 1.86 ENST00000359495.2
ENST00000379170.4
mitochondrial calcium uniporter regulator 1
chr1_+_111682827 1.84 ENST00000357172.4
choline/ethanolamine phosphotransferase 1
chr11_+_64004888 1.83 ENST00000541681.1
vascular endothelial growth factor B
chr9_+_132427883 1.83 ENST00000372469.4
paired related homeobox 2
chr3_-_47619623 1.82 ENST00000456150.1
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr16_+_85646891 1.81 ENST00000393243.1
Gse1 coiled-coil protein
chr1_-_23670752 1.80 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
heterogeneous nuclear ribonucleoprotein R
chr3_-_13009168 1.80 ENST00000273221.4
IQ motif and Sec7 domain 1
chr12_-_93835665 1.80 ENST00000552442.1
ENST00000550657.1
ubiquitin-conjugating enzyme E2N
chr6_+_157802165 1.79 ENST00000414563.2
ENST00000359775.5
zinc finger, DHHC-type containing 14
chr1_+_165797024 1.79 ENST00000372212.4
uridine-cytidine kinase 2
chr21_-_38445443 1.76 ENST00000360525.4
phosphatidylinositol glycan anchor biosynthesis, class P
chr22_+_50247449 1.76 ENST00000216268.5
zinc finger, BED-type containing 4
chr21_-_44495964 1.76 ENST00000398168.1
ENST00000398165.3
cystathionine-beta-synthase
chr1_-_45805752 1.73 ENST00000354383.6
ENST00000355498.2
ENST00000372100.5
ENST00000531105.1
mutY homolog
chr11_+_1968508 1.73 ENST00000397298.3
ENST00000381519.1
ENST00000397297.3
ENST00000381514.3
ENST00000397294.3
mitochondrial ribosomal protein L23
chr8_+_85097110 1.72 ENST00000517638.1
ENST00000522647.1
RALY RNA binding protein-like
chr4_+_17812525 1.72 ENST00000251496.2
non-SMC condensin I complex, subunit G
chr3_-_121553830 1.71 ENST00000498104.1
ENST00000460108.1
ENST00000349820.6
ENST00000462442.1
ENST00000310864.6
IQ motif containing B1
chr19_+_8509842 1.70 ENST00000325495.4
ENST00000600092.1
ENST00000594907.1
ENST00000596984.1
ENST00000601645.1
heterogeneous nuclear ribonucleoprotein M
chr19_-_8386238 1.70 ENST00000301457.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr17_+_8191815 1.69 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr16_+_85646763 1.69 ENST00000411612.1
ENST00000253458.7
Gse1 coiled-coil protein
chr21_-_10990830 1.68 ENST00000361285.4
ENST00000342420.5
ENST00000328758.5
transmembrane phosphatase with tensin homology
chr7_+_106685079 1.67 ENST00000265717.4
protein kinase, cAMP-dependent, regulatory, type II, beta
chr3_-_10749696 1.67 ENST00000397077.1
ATPase, Ca++ transporting, plasma membrane 2
chr22_+_32340481 1.66 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr3_+_49058444 1.66 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr2_-_136743039 1.65 ENST00000537273.1
aspartyl-tRNA synthetase
chr20_+_11871433 1.64 ENST00000399006.2
ENST00000405977.1
BTB (POZ) domain containing 3
chr5_-_7869108 1.63 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FAST kinase domains 3
chr21_-_10990888 1.63 ENST00000298232.7
transmembrane phosphatase with tensin homology
chr3_-_133380731 1.63 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr1_-_23670813 1.62 ENST00000374612.1
heterogeneous nuclear ribonucleoprotein R
chr1_-_92949505 1.62 ENST00000370332.1
growth factor independent 1 transcription repressor
chr22_+_29664248 1.62 ENST00000406548.1
ENST00000437155.2
ENST00000415761.1
ENST00000331029.7
EWS RNA-binding protein 1
chr9_-_111696224 1.62 ENST00000537196.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr20_+_11871371 1.59 ENST00000254977.3
BTB (POZ) domain containing 3
chr7_+_99775366 1.58 ENST00000394018.2
ENST00000416412.1
stromal antigen 3
chr13_-_41635512 1.58 ENST00000405737.2
E74-like factor 1 (ets domain transcription factor)
chr19_+_50353944 1.57 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
prostate tumor overexpressed 1
chr6_-_125623046 1.56 ENST00000608295.1
ENST00000398153.2
ENST00000608284.1
ENST00000368377.4
HD domain containing 2
chr5_-_78809950 1.55 ENST00000334082.6
homer homolog 1 (Drosophila)
chr7_+_102073966 1.55 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
ORAI calcium release-activated calcium modulator 2
chr14_-_105635090 1.54 ENST00000331782.3
ENST00000347004.2
jagged 2
chr10_-_121302195 1.54 ENST00000369103.2
regulator of G-protein signaling 10
chr11_-_134093827 1.53 ENST00000534548.2
non-SMC condensin II complex, subunit D3
chr16_+_11038345 1.52 ENST00000409790.1
C-type lectin domain family 16, member A
chr7_+_73588665 1.52 ENST00000353999.6
eukaryotic translation initiation factor 4H
chr22_+_20105259 1.52 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr11_+_86748863 1.51 ENST00000340353.7
transmembrane protein 135
chr15_-_90645679 1.50 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr13_-_39612176 1.50 ENST00000352251.3
ENST00000350125.3
proline and serine rich 1
chr2_+_232575128 1.50 ENST00000412128.1
prothymosin, alpha
chr3_+_8775466 1.48 ENST00000343849.2
ENST00000397368.2
caveolin 3
chr2_-_70529180 1.47 ENST00000450256.1
ENST00000037869.3
family with sequence similarity 136, member A
chr14_+_50234309 1.47 ENST00000298307.5
kelch domain containing 2
chr1_-_154531095 1.46 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HES1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
4.0 11.9 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
3.2 9.7 GO:0046102 inosine metabolic process(GO:0046102)
3.2 9.6 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
2.9 2.9 GO:0070670 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
2.6 7.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
1.8 5.4 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
1.7 5.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
1.5 7.4 GO:0034971 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R17 methylation(GO:0034971)
1.5 11.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.5 4.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
1.4 4.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
1.2 3.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.2 4.8 GO:0046452 dihydrofolate metabolic process(GO:0046452)
1.1 3.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.1 8.9 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
1.1 7.6 GO:0045007 depurination(GO:0045007)
1.1 4.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
1.1 3.2 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
1.0 3.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.9 2.7 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.9 8.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.9 3.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.8 2.5 GO:0061198 fungiform papilla formation(GO:0061198)
0.8 2.5 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.8 4.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.7 2.2 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.7 2.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.7 2.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.7 2.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.7 2.8 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.7 2.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.7 2.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.7 5.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.6 1.8 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.6 2.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.5 2.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.5 1.6 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.5 3.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.5 1.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.5 24.1 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.5 1.5 GO:0006097 glyoxylate cycle(GO:0006097)
0.5 2.9 GO:0044211 CTP salvage(GO:0044211)
0.5 1.9 GO:0002572 pro-T cell differentiation(GO:0002572)
0.5 1.9 GO:0032053 ciliary basal body organization(GO:0032053)
0.5 1.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.5 1.8 GO:0019086 late viral transcription(GO:0019086)
0.5 14.3 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.5 2.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.5 2.3 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.4 3.1 GO:0035799 ureter maturation(GO:0035799)
0.4 2.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.4 4.0 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.4 2.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.4 3.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 3.9 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4 2.1 GO:0072553 terminal button organization(GO:0072553)
0.4 1.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.4 18.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.4 2.8 GO:1902570 protein localization to nucleolus(GO:1902570)
0.4 1.2 GO:0046098 guanine metabolic process(GO:0046098)
0.4 3.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.4 1.5 GO:0018094 protein polyglycylation(GO:0018094)
0.4 1.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.4 0.4 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.4 1.1 GO:0100009 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.4 3.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.4 5.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.4 2.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.4 1.1 GO:0008355 olfactory learning(GO:0008355)
0.4 1.1 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.4 1.5 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.4 4.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.3 1.3 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.3 1.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 1.7 GO:0097338 response to clozapine(GO:0097338)
0.3 2.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.3 1.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 3.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 2.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.3 2.5 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3 1.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.3 1.2 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 2.7 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.3 1.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.3 2.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 7.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 0.9 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 2.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 1.1 GO:0001743 optic placode formation(GO:0001743) axial mesoderm morphogenesis(GO:0048319)
0.3 0.8 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.3 7.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 1.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.3 1.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 2.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.3 1.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 1.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 2.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 0.8 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.2 0.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 0.2 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2 2.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 5.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 4.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 0.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 3.7 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 1.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 6.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 2.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 2.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.4 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.2 0.6 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.2 0.6 GO:0098502 DNA dephosphorylation(GO:0098502)
0.2 1.8 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.2 1.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 1.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 0.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 4.7 GO:0061157 mRNA destabilization(GO:0061157)
0.2 1.9 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 0.6 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 1.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 0.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 1.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 0.5 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 0.7 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.2 0.5 GO:0021586 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 0.5 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 1.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.2 1.0 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 4.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 1.8 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.2 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 1.5 GO:0070459 prolactin secretion(GO:0070459)
0.2 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 1.4 GO:1902415 regulation of mRNA binding(GO:1902415)
0.2 1.6 GO:0015889 cobalamin transport(GO:0015889)
0.2 1.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 1.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 2.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 2.9 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.2 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.8 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 4.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.6 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 1.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 1.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.1 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.5 GO:1904628 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 2.1 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 1.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.6 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 1.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 7.0 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 4.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 4.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.8 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.1 0.7 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.7 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 14.4 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.9 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 2.4 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.4 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 1.5 GO:0014029 neural crest formation(GO:0014029)
0.1 1.4 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 1.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 3.5 GO:0006270 DNA replication initiation(GO:0006270)
0.1 4.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.8 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 1.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 1.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 6.0 GO:0021762 substantia nigra development(GO:0021762)
0.1 0.5 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 1.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.5 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.7 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.6 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.0 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.7 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.1 0.4 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 2.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.2 GO:0071287 phytoalexin metabolic process(GO:0052314) cellular response to manganese ion(GO:0071287)
0.1 1.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 1.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.9 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1 0.4 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 1.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.3 GO:2000410 regulation of thymocyte migration(GO:2000410)
0.1 1.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.8 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 1.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.6 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.6 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.1 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 1.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:2000724 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 2.4 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.8 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.1 1.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.1 0.4 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.1 0.2 GO:2000275 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) regulation of oxidative phosphorylation uncoupler activity(GO:2000275) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.4 GO:0014050 negative regulation of glutamate secretion(GO:0014050) negative regulation of serotonin secretion(GO:0014063)
0.1 1.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.5 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.1 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.1 2.8 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.2 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 1.6 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 3.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 4.0 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.6 GO:0046036 UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.1 0.9 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.4 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 4.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.4 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.3 GO:0051013 microtubule severing(GO:0051013)
0.1 2.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.7 GO:0051683 establishment of Golgi localization(GO:0051683) Golgi reassembly(GO:0090168)
0.0 0.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.2 GO:0035640 exploration behavior(GO:0035640)
0.0 0.5 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.0 0.3 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.5 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 1.3 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.3 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 1.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0015791 polyol transport(GO:0015791)
0.0 0.4 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.8 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.9 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.6 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 3.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 2.1 GO:0045453 bone resorption(GO:0045453)
0.0 0.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 10.4 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 6.3 GO:0006364 rRNA processing(GO:0006364)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) regulation of DNA methylation(GO:0044030)
0.0 0.7 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 3.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.9 GO:0006260 DNA replication(GO:0006260)
0.0 0.1 GO:1902268 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.9 GO:0007140 male meiosis(GO:0007140)
0.0 0.1 GO:1901374 acetate ester transport(GO:1901374)
0.0 1.6 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.5 GO:0043065 positive regulation of apoptotic process(GO:0043065)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 2.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.8 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.7 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 1.5 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.9 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.1 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 3.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.5 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229)
0.0 0.6 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 1.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.6 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 21.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.0 18.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.0 3.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.9 3.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.9 22.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.8 2.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.7 2.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.6 2.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.6 8.4 GO:0042555 MCM complex(GO:0042555)
0.6 1.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.6 2.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.6 2.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.5 2.0 GO:0000811 GINS complex(GO:0000811)
0.5 2.0 GO:1990745 EARP complex(GO:1990745)
0.5 2.3 GO:0001940 male pronucleus(GO:0001940)
0.5 1.8 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.4 0.9 GO:0033186 CAF-1 complex(GO:0033186)
0.4 2.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 2.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 2.7 GO:0061700 GATOR2 complex(GO:0061700)
0.4 1.5 GO:0000799 nuclear condensin complex(GO:0000799)
0.3 3.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 1.9 GO:0070545 PeBoW complex(GO:0070545)
0.3 4.7 GO:0001741 XY body(GO:0001741)
0.3 2.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.3 1.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 1.7 GO:0000796 condensin complex(GO:0000796)
0.3 8.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 1.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.1 GO:0030314 junctional membrane complex(GO:0030314)
0.3 1.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.3 1.6 GO:0030893 meiotic cohesin complex(GO:0030893)
0.2 4.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 4.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.2 12.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 1.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 1.1 GO:1902555 endoribonuclease complex(GO:1902555)
0.2 1.7 GO:0042382 paraspeckles(GO:0042382)
0.2 5.5 GO:0035371 microtubule plus-end(GO:0035371)
0.2 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 3.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 12.9 GO:0015030 Cajal body(GO:0015030)
0.2 3.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 2.6 GO:0090543 Flemming body(GO:0090543)
0.2 1.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 3.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 1.8 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.2 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 2.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 4.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.2 GO:0010369 chromocenter(GO:0010369)
0.1 1.1 GO:0005642 annulate lamellae(GO:0005642)
0.1 3.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 4.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.9 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 3.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.4 GO:0016342 catenin complex(GO:0016342)
0.1 5.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 11.5 GO:0060170 ciliary membrane(GO:0060170)
0.1 3.2 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 2.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.3 GO:1903349 omegasome membrane(GO:1903349)
0.1 2.7 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 1.1 GO:0005869 dynactin complex(GO:0005869)
0.1 2.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.4 GO:0000791 euchromatin(GO:0000791)
0.1 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:0044326 dendritic spine neck(GO:0044326)
0.1 3.6 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 2.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 3.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 6.5 GO:0014704 intercalated disc(GO:0014704)
0.1 0.2 GO:0045298 tubulin complex(GO:0045298)
0.1 7.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.5 GO:0036020 endolysosome membrane(GO:0036020)
0.1 1.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.1 2.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.4 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.7 GO:0031045 dense core granule(GO:0031045)
0.1 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 8.9 GO:0043679 axon terminus(GO:0043679)
0.1 3.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 4.8 GO:0000793 condensed chromosome(GO:0000793)
0.1 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 3.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.9 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.2 GO:0002102 podosome(GO:0002102)
0.1 2.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.4 GO:0000125 PCAF complex(GO:0000125)
0.1 2.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 6.6 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.7 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.7 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 5.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 3.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 3.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0035061 Smc5-Smc6 complex(GO:0030915) interchromatin granule(GO:0035061)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 11.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 8.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.3 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 7.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.2 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 1.2 GO:0005813 centrosome(GO:0005813)
0.0 0.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)
0.0 2.9 GO:0030424 axon(GO:0030424)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 8.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:0098793 presynapse(GO:0098793)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0008859 exoribonuclease II activity(GO:0008859)
4.0 11.9 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
3.6 21.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.9 7.6 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
1.8 5.4 GO:0004122 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
1.8 8.9 GO:0070644 vitamin D response element binding(GO:0070644)
1.5 4.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.5 4.4 GO:0003883 CTP synthase activity(GO:0003883)
1.3 14.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.3 5.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.2 8.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.1 9.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.0 4.2 GO:0038025 reelin receptor activity(GO:0038025)
1.0 18.3 GO:0001054 RNA polymerase I activity(GO:0001054)
1.0 3.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.9 7.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.9 2.7 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.9 2.6 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.8 5.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.8 8.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.7 2.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.7 2.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.7 2.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.6 3.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.6 3.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.5 1.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.5 1.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.5 3.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.5 1.6 GO:0015235 cobalamin transporter activity(GO:0015235)
0.5 2.0 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.5 1.5 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.5 3.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 1.0 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.5 2.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.5 2.8 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.5 1.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.4 2.9 GO:0004849 uridine kinase activity(GO:0004849)
0.4 1.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.4 2.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 1.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.4 3.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.4 1.5 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.4 1.5 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.4 2.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.4 1.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.4 1.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.4 1.4 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.3 2.7 GO:0097100 supercoiled DNA binding(GO:0097100)
0.3 2.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 2.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.3 1.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.3 7.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 3.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 2.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.3 2.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 3.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 2.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 0.7 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.2 1.8 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 2.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.2 10.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 9.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 1.0 GO:0070097 delta-catenin binding(GO:0070097)
0.2 4.3 GO:0004707 MAP kinase activity(GO:0004707)
0.2 1.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 0.6 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 1.5 GO:0071253 connexin binding(GO:0071253)
0.2 0.9 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 3.2 GO:0005522 profilin binding(GO:0005522)
0.2 7.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 1.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 0.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 1.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 3.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 0.5 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 4.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 2.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.6 GO:0016499 orexin receptor activity(GO:0016499)
0.2 0.8 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 1.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 3.9 GO:0000287 magnesium ion binding(GO:0000287)
0.2 2.9 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.9 GO:0030515 snoRNA binding(GO:0030515)
0.1 1.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.5 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.1 0.9 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.6 GO:0052845 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 6.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 5.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.0 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.6 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.9 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 1.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 4.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 3.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 3.2 GO:0030332 cyclin binding(GO:0030332)
0.1 2.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 1.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 1.9 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.0 GO:0034056 estrogen response element binding(GO:0034056)
0.1 4.7 GO:0019843 rRNA binding(GO:0019843)
0.1 2.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.1 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 6.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.2 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 2.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.0 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 2.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.4 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 2.7 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 0.7 GO:0031386 protein tag(GO:0031386)
0.1 2.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.8 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 6.2 GO:0004386 helicase activity(GO:0004386)
0.1 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.1 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.7 GO:0070628 proteasome binding(GO:0070628)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.8 GO:0031005 filamin binding(GO:0031005)
0.0 1.1 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 4.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 1.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 7.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0052725 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.0 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.0 GO:0035326 enhancer binding(GO:0035326)
0.0 1.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 5.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 1.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 3.0 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 4.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 1.3 GO:0016740 transferase activity(GO:0016740)
0.0 0.1 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 8.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 0.7 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.4 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0019902 phosphatase binding(GO:0019902)
0.0 1.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.1 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0008146 sulfotransferase activity(GO:0008146)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 PID IL3 PATHWAY IL3-mediated signaling events
0.3 13.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 2.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 2.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 14.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 7.8 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 8.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 6.5 PID ATR PATHWAY ATR signaling pathway
0.1 5.0 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.6 PID AURORA A PATHWAY Aurora A signaling
0.1 1.1 PID MYC PATHWAY C-MYC pathway
0.1 6.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 3.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 11.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.8 PID ATM PATHWAY ATM pathway
0.1 2.3 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 3.6 PID E2F PATHWAY E2F transcription factor network
0.1 2.5 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.7 PID BARD1 PATHWAY BARD1 signaling events
0.1 2.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 1.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 18.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.7 35.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 10.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.5 12.2 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.4 6.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 9.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 2.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 7.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 4.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 3.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.3 2.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 1.8 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.2 2.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 1.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 5.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 4.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 4.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 3.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 5.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 3.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 4.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 1.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 2.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 14.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 2.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 7.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.8 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.8 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 4.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 5.2 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 1.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 0.7 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 2.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 21.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 3.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 1.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 3.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 6.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 2.7 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 3.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 3.0 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.1 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 3.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 2.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 3.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 2.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 3.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.4 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA